Page last updated: 2024-08-21

pyrimidine and thiamine

pyrimidine has been researched along with thiamine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199023 (57.50)18.7374
1990's2 (5.00)18.2507
2000's7 (17.50)29.6817
2010's6 (15.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Kumaoka, H; Tazuya, K; Yamada, K2
David, S; Estramareix, B3
Downs, DM; Zilles, JL1
Kumaoka, H; Tanaka, K; Tazuya, K; Yamada, K1
Allen, S; Downs, DM; Zilles, JL1
CHARETON, J; CHARONNAT, R; CHIGHIZOLA, R; EDEL, V; LECHAT, P; MOURIQUAND, G2
BALIAKINA, MV; PREOBRAZHENSKII, NA; RUBTSOV, Ia; ZAITSEVA, EV1
HARRIS, DL1
GUTHRIE, R; HILLMAN, MJ; LOEBECK, ME1
BROWN, GM; CAMIENER, GW1
COSCARELLI, W; PRAMER, D1
HIRAI, K; TAKAMIZAWA, A1
FUJII, T; HASHITANI, Y; KAWAI, F; MITSUDA, H1
HAMASHIMA, Y; HIRAI, K; SATO, H; TAKAMIZAWA, A1
BROWN, GM; GOLDSTEIN, GA1
MOYED, HS1
ABDERHALDEN, R1
GUTHRIE, R; PINE, MJ1
FUJITA, T; IWASHIMA, A; KAWASAKI, T; NOSE, Y; UEDA, K1
Dougherty, MJ; Downs, DM1
Akaji, K; Kawasaki, Y; Konno, H; Nosaka, K; Onozuka, M1
Amrhein, N; Arigoni, D; Bürkle, L; Fernie, AR; Fitzpatrick, TB; Müller, N; Nunes-Nesi, A; Raschke, M1
Begley, TP; Booker, SJ; Chatterjee, A; Ealick, SE; Grove, TL; Krebs, C; Lee, M; Li, Y; Zhang, Y1
Begley, TP; Ealick, SE; Jurgenson, CT1
ALEXANDER, B; LANDWEHR, G; MITCHELL, F1
MICKELSEN, O1
CASTER, WO; KEYS, A; MICKELSEN, O1
Cheng, X; Fan, H; Huang, Z; Ling, HQ; Wu, H; Zhao, W1
Abdelwahed, SH; Begley, TP; Ealick, SE; Fenwick, MK; Mehta, AP; Zhang, Y1
Hayashi, M; Kijima, Y; Tazuya-Murayama, K; Yamada, K1
Heidari, Y; Howe, GW; Kluger, R1
Amthor, JS; Bruner, SD; Ding, Y; Gregory, JF; Hanson, AD; Niehaus, TD; Sun, J1
Angert, ER; Edwards, KA; Kraft, CE; Sannino, DR1
Dong, N; Dong, T; Hao, W; Li, Y; Qin, T; Sun, J; Sun, R; Wang, Q; Wang, W; Wang, Y; Wei, C; Wu, B; Yang, Q; Yang, S; Zhang, Y1
Downs, DM; Paxhia, MD; Swanson, MS1
Alspach, JD; Ingraham, LL1

Reviews

2 review(s) available for pyrimidine and thiamine

ArticleYear
Isotopically labeled precursors and mass spectrometry in elucidating biosynthesis of pyrimidine moiety of thiamin in Saccharomyces cerevisiae.
    Methods in enzymology, 1997, Volume: 279

    Topics: Mass Spectrometry; Pyrimidines; Radioisotopes; Saccharomyces cerevisiae; Thiamine

1997
The structural and biochemical foundations of thiamin biosynthesis.
    Annual review of biochemistry, 2009, Volume: 78

    Topics: Animals; Eukaryotic Cells; Fungi; Humans; Plants; Prokaryotic Cells; Pyrimidines; Thiamine; Thiazoles

2009

Other Studies

38 other study(ies) available for pyrimidine and thiamine

ArticleYear
Incorporation of histidine into the pyrimidine moiety of thiamin in Saccharomyces cerevisiae.
    Biochimica et biophysica acta, 1989, Jan-27, Volume: 990, Issue:1

    Topics: Aspartic Acid; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Histidine; Mass Spectrometry; Nitrogen Radioisotopes; Pyrimidines; Saccharomyces cerevisiae; Thiamine

1989
Biosynthesis of thiamine: origin of the methyl carbon atom of the pyrimidine moiety in Salmonella typhimurium.
    Biochemical and biophysical research communications, 1986, Feb-13, Volume: 134, Issue:3

    Topics: Binding Sites; Chemical Phenomena; Chemistry; Methylation; Pyrimidines; Ribonucleotides; Ribose; Salmonella typhimurium; Thiamine

1986
A novel involvement of the PurG and PurI proteins in thiamine synthesis via the alternative pyrimidine biosynthetic (APB) pathway in Salmonella typhimurium.
    Genetics, 1996, Volume: 144, Issue:3

    Topics: Alleles; Mutagenesis; Purines; Pyrimidines; Salmonella typhimurium; Thiamine

1996
Biosynthesis of thiamin under anaerobic conditions in Saccharomyces cerevisiae.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:1

    Topics: Aerobiosis; Anaerobiosis; Carbon Radioisotopes; Formates; Glycine; Mass Spectrometry; Nitrogen Isotopes; Oxygen; Pyridoxine; Pyrimidines; Saccharomyces cerevisiae; Thiamine; Thiazoles

2000
Metabolic flux in both the purine mononucleotide and histidine biosynthetic pathways can influence synthesis of the hydroxymethyl pyrimidine moiety of thiamine in Salmonella enterica.
    Journal of bacteriology, 2002, Volume: 184, Issue:22

    Topics: Aminoimidazole Carboxamide; Bacterial Proteins; Gene Expression Regulation, Bacterial; Histidine; Point Mutation; Purines; Pyrimidines; Ribonucleotides; Salmonella enterica; Suppression, Genetic; Thiamine; Thiamine Pyrophosphate

2002
[Thiamine and its pyrimidine and thiazole constituents in relation to the vestibular index].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1953, Apr-08, Volume: 236, Issue:14

    Topics: Pyrimidines; Thiamine; Thiazoles; Vestibule, Labyrinth

1953
[Modification of the vestibular chronologic index of thiamine and of its pyrimidine and thiazole moieties under the influence of air].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1953, Oct-05, Volume: 237, Issue:14

    Topics: Humans; Pyrimidines; Thiamine; Thiazoles; Vestibular Nerve; Vestibule, Labyrinth

1953
[Investigations on pyrimidine component of vitamin B1].
    Trudy. Moscow (Russia). Vsesoiuznyi nauchno-issledovatel'skii vitaminnyi institut, 1953, Volume: 4

    Topics: Humans; Pyrimidines; Thiamine

1953
Interaction of thiamine and pyridoxine in Neurospora. II. Competition between pyridoxine and the pyrimidine precursor of thiamine.
    Archives of biochemistry and biophysics, 1956, Volume: 60, Issue:1

    Topics: Biochemical Phenomena; Humans; Neurospora; Pyridoxine; Pyrimidines; Thiamine; Vitamin B 6

1956
Sensitivity to analogs of thiamine pyrimidine associated with resistance to amethopterin or purine antagonists.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 94, Issue:4

    Topics: Antineoplastic Agents; Folic Acid Antagonists; Humans; Leukemia; Methotrexate; Purines; Pyrimidines; Thiamine

1957
[Incorporation of [C-14]-formate into the pyrimidine of thiamine by Saccharomyces cerevisiae].
    Biochimica et biophysica acta, 1960, Aug-26, Volume: 42

    Topics: Biochemical Phenomena; Formates; Pyrimidines; Saccharomyces cerevisiae; Thiamine; Vitamin A; Yeasts

1960
[On the biogenesis of the pyrimidine of thiamine].
    Biochimica et biophysica acta, 1961, May-13, Volume: 49

    Topics: Biochemical Phenomena; Lipid Metabolism; Pyrimidines; Thiamine; Vitamin A

1961
The biosynthesis of thiamine. 1. Enzymatic formation of thiamine and phosphate esters of the pyrimidine moiety of thiamine.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Esters; Phosphates; Pyrimidines; Thiamine

1960
Nutrition and growth of Arthrobotrys conoides.
    Journal of bacteriology, 1962, Volume: 84

    Topics: Animals; Ascomycota; Biotin; Fungi; Glucose; Nematoda; Pyrimidines; Thiamine; Vitamins; Zinc

1962
Studies on the pyrimidine derivatives. XX. On the studies of S-alkoxycarbonylthiamine. (1).
    Chemical & pharmaceutical bulletin, 1962, Volume: 10

    Topics: Antihypertensive Agents; Pyrimidines; Thiamine

1962
UTILIZATION OF PYRIMIDINE MOIETY IN VIVO FOR THE BIOGENSIS OF THIAMINE IN PLANT.
    The Journal of vitaminology, 1963, Mar-10, Volume: 9

    Topics: Metabolism; Oryza; Plants, Edible; Pyrimidines; Research; Thiamine

1963
STUDIES ON THE PYRIMIDINE DERIVATIVES. XXIV. SYNTHESES OF SEVERAL THIOL-TYPE THIAMINE DERIVATIVES AND THEIR PRIMARY SCREENING TESTS.
    Chemical & pharmaceutical bulletin, 1963, Volume: 11

    Topics: Antihypertensive Agents; Blood Chemical Analysis; Chemistry, Pharmaceutical; Pyrimidines; Rabbits; Research; Sulfhydryl Compounds; Thiamine

1963
THE BIOSYNTHESIS OF THIAMINE. V. STUDIES CONCERNING PRECURSORS OF THE PYRIMIDINE MOIETY.
    Archives of biochemistry and biophysics, 1963, Volume: 103

    Topics: Acetates; Aspartic Acid; Carbon Isotopes; Chromatography; Escherichia coli; Formates; Glycine; Ion Exchange Resins; Metabolism; Methionine; Orotic Acid; Pyrimidines; Research; Serine; Sulfonic Acids; Thiamine; Uracil

1963
INHIBITION OF THE BIOSYNTHESIS OF THE PYRIMIDINE PORTION OF THIAMINE BY ADENOSINE.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Adenosine; Enterobacter aerogenes; Histidine; Metabolism; Mutation; Nucleosides; Pharmacology; Purines; Pyrimidines; Research; Succinates; Thiamine; Thiazoles

1964
[Antagonism between pyridoxine and pyrimidine components of aneurin].
    Zeitschrift fur Vitamin-, Hormon- und Fermentforschung, 1954, Volume: 6, Issue:4-5

    Topics: Pyridoxine; Pyrimidines; Thiamine; Vitamin B 6

1954
Incorporation of formate-C 14 into the pyrimidine moiety of thiamine.
    Journal of bacteriology, 1959, Volume: 78

    Topics: Formates; Pyrimidines; Thiamine

1959
Enzymatic synthesis of thiamine. II. The thiamine synthesis from pyrimidine and thiazole phosphates and the enzymatic synthesis of pyrimidine mono- and diphosphate and thiazole monophosphate.
    The Journal of vitaminology, 1961, Jun-10, Volume: 7

    Topics: Biochemical Phenomena; Diphosphates; Enzymes; Phosphates; Pyrimidines; Thiamine; Thiazoles

1961
A mutant allele of rpoD results in increased conversion of aminoimidazole ribotide to hydroxymethyl pyrimidine in Salmonella enterica.
    Journal of bacteriology, 2004, Volume: 186, Issue:12

    Topics: Alleles; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Mutation; Pyrimidines; Ribonucleotides; Salmonella enterica; Sigma Factor; Thiamine; Transcription, Genetic

2004
Involvement of thiaminase II encoded by the THI20 gene in thiamin salvage of Saccharomyces cerevisiae.
    FEMS yeast research, 2008, Volume: 8, Issue:2

    Topics: Gene Deletion; Hydrolases; Oxythiamine; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotransferases (Phosphate Group Acceptor); Pyrimidines; Pyrithiamine; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiamine

2008
Vitamin B1 biosynthesis in plants requires the essential iron sulfur cluster protein, THIC.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-04, Volume: 104, Issue:49

    Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Iron-Sulfur Proteins; Molecular Sequence Data; Pyrimidines; Thiamine

2007
Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily.
    Nature chemical biology, 2008, Volume: 4, Issue:12

    Topics: Bacterial Proteins; Caulobacter crescentus; Deoxyadenosines; Evolution, Molecular; Iron-Sulfur Proteins; Protein Conformation; Pyrimidines; Thiamine

2008
Studies of thiamine metabolism in man; thiamine and pyrimidine excretion with special reference to the relationship between injected and excreted thiamine in normal and abnormal subjects.
    The Journal of clinical investigation, 1946, Volume: 25

    Topics: Biological Transport; Humans; Injections; Male; Pyrimidines; Thiamine

1946
The urinary excretion of thiamine, pyramin (the pyrimidine-like component of thiamine) and riboflavin by man in semistarvation.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Body Fluids; Humans; Male; Pyridazines; Pyrimidines; Riboflavin; Starvation; Thiamine

1946
Relation between urinary excretion of thiamine and pyramin (the pyrimidine-like component of thiamine).
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Biochemical Phenomena; Pyridazines; Pyrimidines; Thiamine

1946
Tomato LeTHIC is an Fe-requiring HMP-P synthase involved in thiamine synthesis and regulated by multiple factors.
    Plant & cell physiology, 2011, Volume: 52, Issue:6

    Topics: 5' Untranslated Regions; Amino Acid Sequence; Arabidopsis Proteins; Bacterial Proteins; Base Sequence; Chloroplasts; DNA, Plant; Gene Expression Regulation, Plant; Genes, Plant; Genetic Complementation Test; Iron; Iron-Sulfur Proteins; Light; Molecular Sequence Data; Phenotype; Phylogeny; Plant Leaves; Plant Proteins; Plant Roots; Pyrimidines; Riboswitch; Sequence Analysis, Protein; Solanum lycopersicum; Thiamine; Thiamine Pyrophosphate

2011
Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.
    Nature communications, 2015, Mar-27, Volume: 6

    Topics: Bacterial Proteins; Catalysis; Catalytic Domain; Cobamides; Crystallography, X-Ray; Intramolecular Transferases; Iron-Sulfur Proteins; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidines; S-Adenosylmethionine; Thiamine

2015
The Biosynthesis of the Pyrimidine Moiety of Thiamin in Halobacterium salinarum.
    Journal of nutritional science and vitaminology, 2016, Volume: 62, Issue:2

    Topics: Biosynthetic Pathways; Escherichia coli; Glycine; Halobacterium salinarum; Histidine; Purines; Pyridoxine; Pyrimidines; Ribonucleotides; Saccharomyces cerevisiae; Thiamine; Thiazoles

2016
The reactivity of lactyl-oxythiamin implies the role of the amino-pyrimidine in thiamin catalyzed decarboxylation.
    Bioorganic chemistry, 2016, Volume: 69

    Topics: Catalysis; Decarboxylation; Molecular Structure; Oxythiamine; Pyrimidines; Pyruvic Acid; Thiamine

2016
Redesigning thiamin synthesis: Prospects and potential payoffs.
    Plant science : an international journal of experimental plant biology, 2018, Volume: 273

    Topics: Metabolic Engineering; Metabolic Networks and Pathways; Oxygen; Plants; Pyrimidines; Synthetic Biology; Thiamine; Thiazoles

2018
Thiaminase I Provides a Growth Advantage by Salvaging Precursors from Environmental Thiamine and Its Analogs in Burkholderia thailandensis.
    Applied and environmental microbiology, 2018, 09-15, Volume: 84, Issue:18

    Topics: Alkyl and Aryl Transferases; Bacterial Proteins; Burkholderia; Pyrimidines; Thiamine; Thiazoles

2018
    International journal of molecular sciences, 2020, Feb-18, Volume: 21, Issue:4

    Topics: Biosynthetic Pathways; DNA Repair; Fluorescence; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Genetic Complementation Test; Green Fluorescent Proteins; Mutation; Mycelium; Nicotiana; Plant Roots; Plants, Genetically Modified; Pyrimidines; Thiamine; Ultraviolet Rays; Verticillium; Virulence

2020
Functional characterization of the HMP-P synthase of Legionella pneumophila (Lpg1565).
    Molecular microbiology, 2021, Volume: 115, Issue:4

    Topics: Amino Acid Sequence; Bacterial Proteins; Biosynthetic Pathways; Iron; Iron-Sulfur Proteins; Legionella pneumophila; Phylogeny; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Pyrimidines; Saccharomyces cerevisiae; Salmonella enterica; Thiamine

2021
Inhibition of acetylcholinesterase by thiamine. A structure-function study.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:1

    Topics: Animals; Cholinesterase Inhibitors; Eels; Kinetics; Structure-Activity Relationship; Thiamine

1977