pyrimidine has been researched along with teriflunomide in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flao, KL; Francesconi, E; Hidden, H; Meakin, C; Millet, S; Ruuth, E; Spinella-Jaegle, S; Thomson, TA | 1 |
| Begué-Pastor, N; Benavent, S; Burger, D; Chicheportiche, R; Dayer, JM; Gruaz, L; Kaufmann, MT | 1 |
| Arai, Y; Hakeda, Y; Kaneda, T; Kobayashi, Y; Kumegawa, M; Sato, T; Shin, K; Ueyama, S; Yoshida, Y | 1 |
| Bushman, LR; Chen, P; Hail, N; Rower, J | 1 |
| Agnihotri, S; Bao, S; Bhargava, S; Gimple, RC; Jiang, L; Kim, LJY; Li, X; Mack, SC; Mischel, PS; Morton, AR; Prager, BC; Qiu, Z; Rich, JN; Shi, Y; Tao, W; Wang, X; Wu, Q; Yang, K; Zhang, G; Zhao, L; Zhou, W; Zhu, Z | 1 |
5 other study(ies) available for pyrimidine and teriflunomide
| Article | Year |
|---|---|
In vitro and in Vivo inhibition of immunoglobulin secretion by the immunosuppressive compound HR325 is reversed by exogenous uridine.
Topics: Aniline Compounds; Animals; Biphenyl Compounds; Cell Membrane; Cells, Cultured; Crotonates; Dihydroorotate Dehydrogenase; Drug Antagonism; Enzyme Inhibitors; Erythrocytes; Hydroxybutyrates; Immunoglobulin G; Immunoglobulin kappa-Chains; Immunoglobulin M; Immunoglobulins; Immunosuppressive Agents; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitriles; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; Sheep; Spleen; Toluidines; Uridine | 2002 |
The active metabolite of leflunomide, A77 1726, inhibits the production of prostaglandin E(2), matrix metalloproteinase 1 and interleukin 6 in human fibroblast-like synoviocytes.
Topics: Aniline Compounds; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arthritis, Rheumatoid; Cells, Cultured; Crotonates; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydroxybutyrates; Interleukin-6; Isoenzymes; Matrix Metalloproteinase 1; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Nitriles; Prostaglandin-Endoperoxide Synthases; Pyrimidines; RNA, Messenger; Synovial Membrane; Toluidines; Uridine | 2003 |
The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.
Topics: Aniline Compounds; Animals; Binding Sites; Bone Resorption; Carrier Proteins; Cell Differentiation; Cell Lineage; Cells, Cultured; Crotonates; Electrophoretic Mobility Shift Assay; Hydroxybutyrates; Isoxazoles; Leflunomide; Membrane Glycoproteins; Mice; NF-kappa B; Nitriles; Osteoclasts; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Pyrimidines; Rabbits; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Toluidines | 2004 |
Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Crotonates; Cytostatic Agents; Energy Metabolism; Epithelial Cells; Flow Cytometry; Humans; Hydroxybutyrates; Keratinocytes; Mitochondria; Nitriles; Oxygen Consumption; Precancerous Conditions; Pyrimidines; Reactive Oxygen Species; S Phase; Skin Neoplasms; Toluidines; Uridine | 2010 |
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells.
Topics: Animals; Biosynthetic Pathways; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Crotonates; Dihydroorotate Dehydrogenase; ErbB Receptors; Gene Deletion; Glioblastoma; Humans; Hydroxybutyrates; MAP Kinase Signaling System; Mice; Molecular Targeted Therapy; Neoplastic Stem Cells; Nitriles; Oxidoreductases Acting on CH-CH Group Donors; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Pyrimidines; Toluidines; Treatment Outcome; Up-Regulation | 2019 |