pyrimidine has been researched along with pyrroles in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (92.31) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T | 1 |
| Fotsch, C; St Jean, DJ | 1 |
| Abbate, I; Almerico, AM; Lauria, A; Martorana, A; Patella, C | 1 |
| El-Gamal, MI; Oh, CH | 1 |
| Avasthi, K; Kant, R; Ravikumar, K; Shukla, L | 1 |
| Dommaraju, Y; Prajapati, D | 1 |
| Cai, J; Huang, W; Jin, Q; Tang, F; Wang, Y; Xiang, H; Xin, M; Zhao, X; Zhao, Y | 1 |
| Mei, H; Seela, F; Yang, H | 1 |
| Tang, Q; Wang, J; Wang, W; Wu, C; Xu, S; Zhao, Y; Zheng, P; Zhu, W | 1 |
| Chen, P; Gui, L; Huang, W; Liu, F; Tang, F; Wang, J; Wang, Y; Xin, M; Zhao, X | 1 |
| Honma, T; Kikuzato, K; Koda, Y; Koyama, H; Kukimoto-Niino, M; Mikuni, J; Shirai, F; Shirouzu, M; Tanaka, A; Tomabechi, Y; Yuki, H | 1 |
| Georg, GI; Hawkinson, JE; Herr, JC; Mudaliar, D; Shetty, J; Sinville, R; Ward, T | 1 |
| Duan, Y; Jiang, L; Liu, X; Tang, Q; Wang, LX; Xiao, Z; Xu, S; Zheng, P; Zhi, J; Zhu, W | 1 |
1 review(s) available for pyrimidine and pyrroles
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
12 other study(ies) available for pyrimidine and pyrroles
| Article | Year |
|---|---|
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase | 1981 |
Lead optimization through VLAK protocol: new annelated pyrrolo-pyrimidine derivatives as antitumor agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Humans; Informatics; Pyrimidines; Pyrroles | 2012 |
Diarylureas and diarylamides with pyrrolo[2,3-d]pyrimidine scaffold as broad-spectrum anticancer agents.
Topics: Antineoplastic Agents; Benzamides; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Imatinib Mesylate; Niacinamide; Phenylurea Compounds; Piperazines; Pyrimidines; Pyrroles; Sorafenib | 2014 |
Folded conformations due to arene interactions in dissymmetric and symmetric butylidene-linker models based on pyrazolo[3,4-d]pyrimidine, purine and 7-deazapurine.
Topics: Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Purines; Pyrazoles; Pyrimidines; Pyrroles | 2014 |
A highly efficient group-assisted purification method for the synthesis of poly-functionalized pyrimidin-5-yl-pyrroles via one-pot four-component domino reaction.
Topics: Chemistry Techniques, Synthetic; Chromatography; Green Chemistry Technology; Models, Molecular; Pyrimidines; Pyrroles | 2015 |
Discovery of novel Bruton's tyrosine kinase (BTK) inhibitors bearing a pyrrolo[2,3-d]pyrimidine scaffold.
Topics: Agammaglobulinaemia Tyrosine Kinase; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2015 |
Pyrrolo-dC Metal-Mediated Base Pairs in the Reverse Watson-Crick Double Helix: Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Silver-Ion Binding.
Topics: Base Pairing; Circular Dichroism; DNA; Fluorescence; Heterocyclic Compounds; Ions; Nucleic Acid Conformation; Nucleosides; Pyrimidines; Pyrroles; Silver | 2015 |
Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo[2,3-b]pyridine moiety as c-Met inhibitors.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2016 |
Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors.
Topics: Amines; Cell Line; Humans; Janus Kinase 2; Janus Kinase 3; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles | 2017 |
Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2017 |
Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2).
Topics: Dose-Response Relationship, Drug; High-Throughput Screening Assays; Humans; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2017 |
Discovery of novel pyrrolo-pyridine/pyrimidine derivatives bearing pyridazinone moiety as c-Met kinase inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridazines; Pyridines; Pyrimidines; Pyrroles; Structure-Activity Relationship | 2017 |