Page last updated: 2024-08-21

pyrimidine and deoxycytidine

pyrimidine has been researched along with deoxycytidine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's10 (66.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Evans, VJ; Price, FM; Rotherham, J1
Beuneu, C; Guittet, O; Lemaire, G; Lepoivre, M; Roy, B1
Beijnen, JH; Bosch, TM; Jörger, M; Schellens, JH; Sparidans, RW1
Chrenko, V; Frgala, T; Kocakova, I; Krejci, E; Kubosova, K; Roubalova, E; Sefr, R; Slampa, P; Svoboda, M; Zaloudik, J1
Galmarini, C; Myhren, F; Peters, G; Sandvold, ML1
Eriksson, S; Wang, L1
Cheng, YC; Hsu, CH; Hu, R; Lam, W1
Andersen, NK; Døssing, H; Jensen, F; Nielsen, P; Vester, B1
Batzler, A; Fridley, BL; Jenkins, GD; Ji, Y; Li, F; Li, L; Matimba, A; Wang, L; Weinshilboum, RM1
Burge, M; Clarke, S; Cordwell, C; Gibbs, P; Reece, W; Tebbutt, N1
Bai, Y; Chu, YP; Gong, JF; Li, J; Li, Y; Shen, L; Zhang, XT1
Abrego, J; Asara, JM; Attri, KS; Augustine, JJ; Berim, L; Cantley, LC; Chaika, NV; Dai, B; Dasgupta, A; Fleming, JB; Gebregiworgis, T; Goode, GD; Grandgenett, PM; Grem, JL; Gunda, V; Hankins, JH; Hollingsworth, MA; Illies, AL; Kim, JW; King, RJ; Lazenby, AJ; Ly, QP; Lyssiotis, CA; Mashadova, O; Matés, JM; Mehla, K; Murthy, D; Oliveto, JM; Powers, R; Purohit, V; Sasson, AR; Serkova, NJ; Shukla, SK; Singh, PK; Vernucci, E; Weekes, C; Yu, F1
Biankin, AV; Chantrill, L; Chin, V; Nagrial, A; O'Connor, CA; Scholten, RJ; Sjoquist, K; Yip, D1
Taieb, J; Zaanan, A1
Bijvelds, MJ; Chen, S; de Jonge, HR; Kainov, DE; Li, P; Pan, Q; Peppelenbosch, MP; Wang, Y; Yin, Y1

Reviews

2 review(s) available for pyrimidine and deoxycytidine

ArticleYear
Chemotherapy and radiotherapy for advanced pancreatic cancer.
    The Cochrane database of systematic reviews, 2018, 03-20, Volume: 3

    Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Epirubicin; Fluorouracil; Gemcitabine; Humans; Paclitaxel; Pancreatic Neoplasms; Pyrimidines; Randomized Controlled Trials as Topic; Treatment Outcome

2018
[Predictive and prognostic value of MSI phenotype in adjuvant colon cancer: Who and how to treat?]
    Bulletin du cancer, 2019, Volume: 106, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fluorouracil; Humans; Immunotherapy; Leucovorin; Lymphocytes, Tumor-Infiltrating; Microsatellite Instability; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Phenotype; Prognosis; Pyrimidines

2019

Trials

2 trial(s) available for pyrimidine and deoxycytidine

ArticleYear
An Australian translational study to evaluate the prognostic role of inflammatory markers in patients with metastatic ColorEctal caNcer Treated with bevacizumab (Avastin™) [ASCENT].
    BMC cancer, 2013, Mar-15, Volume: 13

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Inflammation; Leucovorin; Lymphocytes; Male; Neutrophils; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Prognosis; Proportional Hazards Models; Prospective Studies; Pyrimidines; Reproducibility of Results

2013
A phase II study of triweekly paclitaxel and capecitabine combination therapy in patients with fluoropyrimidine-platinum-resistant metastatic gastric adenocarcinoma.
    Journal of cancer research and therapeutics, 2013, Volume: 9 Suppl

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Male; Middle Aged; Paclitaxel; Platinum; Pyrimidines; Stomach Neoplasms

2013

Other Studies

11 other study(ies) available for pyrimidine and deoxycytidine

ArticleYear
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
    Journal of the National Cancer Institute, 1970, Volume: 44, Issue:1

    Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12

1970
Depletion of deoxyribonucleoside triphosphate pools in tumor cells by nitric oxide.
    Free radical biology & medicine, 2004, Feb-15, Volume: 36, Issue:4

    Topics: Animals; Cell Line; Cell Line, Tumor; Cells, Cultured; Cyclic GMP; Deoxycytidine; Deoxyribonucleotides; Dose-Response Relationship, Drug; Humans; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Prodrugs; Pyrimidines; Ribonucleotide Reductases; Spermine

2004
Liquid chromatography-tandem mass spectrometric assay for the analysis of uracil, 5,6-dihydrouracil and beta-ureidopropionic acid in urine for the measurement of the activities of the pyrimidine catabolic enzymes.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jul-24, Volume: 839, Issue:1-2

    Topics: beta-Alanine; Biological Assay; Calibration; Capecitabine; Case-Control Studies; Child; Child, Preschool; Chromatography, Liquid; Deoxycytidine; Enzymes; Female; Fluorouracil; Humans; Infant, Newborn; Male; Pyrimidines; Spectrometry, Mass, Electrospray Ionization; Uracil

2006
Preoperative radiotherapy and concomitant capecitabine treatment induce thymidylate synthase and thymidine phosphorylase mRNAs in rectal carcinoma.
    Neoplasma, 2007, Volume: 54, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoembryonic Antigen; Combined Modality Therapy; Deoxycytidine; Fluorouracil; Genetic Markers; Humans; Middle Aged; Neoplasm Staging; Polymerase Chain Reaction; Pyrimidines; Rectal Neoplasms; RNA, Messenger; Thymidine Phosphorylase; Thymidylate Synthase

2007
The activity of the lipophilic nucleoside derivatives elacytarabine and CP-4126 in a panel of tumor cell lines resistant to nucleoside analogues.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:4-6

    Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Resistance, Neoplasm; HT29 Cells; Humans; Pyrimidines

2010
Tissue specific distribution of pyrimidine deoxynucleoside salvage enzymes shed light on the mechanism of mitochondrial DNA depletion.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:4-6

    Topics: Animals; Chromatography, Ion Exchange; Cytosol; Deoxycytidine; Deoxycytidine Kinase; DNA, Mitochondrial; Liver; Lung; Mitochondria; Phosphorylation; Pyrimidines; Rats; Rats, Sprague-Dawley; Spleen; Thymidine; Thymidine Kinase

2010
UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells.
    PloS one, 2011, May-03, Volume: 6, Issue:5

    Topics: Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Down-Regulation; Enzymes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Nucleoside-Phosphate Kinase; Nucleotides; Pyrimidines; Recombinant Proteins; Ribonucleotides

2011
Duplex and triplex formation of mixed pyrimidine oligonucleotides with stacking of phenyl-triazole moieties in the major groove.
    The Journal of organic chemistry, 2011, Aug-05, Volume: 76, Issue:15

    Topics: Base Sequence; Circular Dichroism; Deoxycytidine; Deoxyuridine; DNA, Complementary; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleosides; Nucleotides; Oligonucleotides; Pyrimidines; RNA, Complementary; Triazoles

2011
Gene set analysis of purine and pyrimidine antimetabolites cancer therapies.
    Pharmacogenetics and genomics, 2011, Volume: 21, Issue:11

    Topics: Antimetabolites; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Genes, Neoplasm; Humans; Neoplasms; Phenotype; Purines; Pyrimidines; Reproducibility of Results; Thioguanine

2011
MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer.
    Cancer cell, 2017, 07-10, Volume: 32, Issue:1

    Topics: Carbon; Deoxycytidine; Digoxin; Drug Resistance, Neoplasm; Gemcitabine; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mucin-1; Pancreatic Neoplasms; Pentose Phosphate Pathway; Prognosis; Pyrimidines; Signal Transduction

2017
Drug screening identifies gemcitabine inhibiting rotavirus through alteration of pyrimidine nucleotide synthesis pathway.
    Antiviral research, 2020, Volume: 180

    Topics: Animals; Antiviral Agents; Biosynthetic Pathways; Caco-2 Cells; Deoxycytidine; Drug Evaluation, Preclinical; Gemcitabine; High-Throughput Screening Assays; Humans; Intestines; Macaca mulatta; Organoids; Pyrimidines; Rotavirus; Rotavirus Infections; Small Molecule Libraries

2020