Page last updated: 2024-08-21

pyrimidine and aspartic acid

pyrimidine has been researched along with aspartic acid in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199011 (55.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's2 (10.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Kumaoka, H; Tazuya, K; Yamada, K1
KORNBERG, A; LIEBERMAN, I1
RAVEL, JM; SHIVE, W; WOODS, L1
WOOLLEY, DW1
BROWN, GM; GOLDSTEIN, GA1
DONACHIE, WD1
COHEN, PP; LINDSAY, RH; NAKAGAWA, H1
CURCI, MR; DONACHI, WD1
BRESNICK, E1
BUCHOWICZ, J; REIFER, I; TOCZKO, K1
HUFF, JW; LIEBERT, KV; SPICER, DS; WRIGHT, LD1
Beaudoin, B; Bray, K; Chen, G; Degenhardt, K; Jin, S; Karp, CM; Kongara, S; Mathew, R; White, E1
Agarwal, MK; Agarwal, ML; Agrawal, S; Amin, AR; Hastak, K; Jackson, MW; Jacobberger, JW; Paul, RK; Sramkoski, RM; Stark, GR; Thakur, VS1
Adler, L; Agron, S; Brandis, A; Dimmock, D; Erez, A; Helbling, D; Itzkovitz, S; Korman, S; Nagamani, SC; Rabinovich, S; Ruppin, E; Sarver, A; Silberman, A; Stettner, N; Sun, Q; Ulitsky, I; Yizhak, K1
Homer, CR; Jatana, S; Kabi, A; Madajka, M; McDonald, C; Papay, F; Ponti, AK1
Bach, C; Baumert, TF; Brino, L; Crouchet, E; El Saghire, H; Garcia, T; Heydmann, L; Kopp, A; Pale, P; Pessaux, P; Schuster, C; Sureau, C; Turon-Lagot, V; Verrier, ER; Weiss, A; Zeisel, MB1
Bellin, L; Del Caño-Ochoa, F; Möhlmann, T; Ramón-Maiques, S; Velázquez-Campoy, A1
Jakkula, P; Khan, N; Kumar, KA; Panigrahi, GC; Qureshi, IA; Qureshi, R1
Cao, D; Chen, C; Chen, L; Chen, X; Hu, X; Kong, F; Li, J; Li, X; Liu, O; Liu, S; Luo, J; Luo, T; Luo, W; Luo, Z; Ma, D; Ming, Z; Peng, K; Wen, M; Xia, L; Xie, Y; Xu, N; Yang, C; Yi, W; Zou, Z1
Atzori, AS; Carboni, E; Gallo, A; Ghilardelli, F; Masoero, F; Rocchetti, G1

Other Studies

20 other study(ies) available for pyrimidine and aspartic acid

ArticleYear
Incorporation of histidine into the pyrimidine moiety of thiamin in Saccharomyces cerevisiae.
    Biochimica et biophysica acta, 1989, Jan-27, Volume: 990, Issue:1

    Topics: Aspartic Acid; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Histidine; Mass Spectrometry; Nitrogen Radioisotopes; Pyrimidines; Saccharomyces cerevisiae; Thiamine

1989
Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydroortic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin.
    The Journal of biological chemistry, 1954, Volume: 207, Issue:2

    Topics: Aspartic Acid; Hydantoins; Orotic Acid; Pyrimidines; Succinates

1954
Relationship of aspartic acid to pyrimidine biosynthesis.
    The Journal of biological chemistry, 1954, Volume: 209, Issue:2

    Topics: Aspartic Acid; Lactobacillus; Pyrimidines; Uracil

1954
3-Methylaspartic acid as a potent antimetabolite of aspartic acid in pyrimidine biosynthesis.
    The Journal of biological chemistry, 1960, Volume: 235

    Topics: Antimetabolites; Aspartic Acid; Escherichia coli; Pyrimidines

1960
THE BIOSYNTHESIS OF THIAMINE. V. STUDIES CONCERNING PRECURSORS OF THE PYRIMIDINE MOIETY.
    Archives of biochemistry and biophysics, 1963, Volume: 103

    Topics: Acetates; Aspartic Acid; Carbon Isotopes; Chromatography; Escherichia coli; Formates; Glycine; Ion Exchange Resins; Metabolism; Methionine; Orotic Acid; Pyrimidines; Research; Serine; Sulfonic Acids; Thiamine; Uracil

1963
THE REGULATION OF PYRIMIDINE BIOSYNTHESIS IN NEUROSPORA CRASSA. I. END-PRODUCT INHIBITION AND REPRESSION OF ASPARTATE CARBAMOYLTRANSFERASE.
    Biochimica et biophysica acta, 1964, Feb-10, Volume: 82

    Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamates; Enzyme Inhibitors; Metabolism; Neurospora; Neurospora crassa; Nucleosides; Phosphates; Pyrimidines; Transferases

1964
PATHWAY OF PYRIMIDINE BIOSYNTHESIS IN PREMETAMORPHIC TADPOLES.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Alanine; Animals; Anura; Aspartic Acid; Carbamates; Carbon Isotopes; Carboxy-Lyases; Glucose; Larva; Liver; Metabolism; Metamorphosis, Biological; Orotic Acid; Phosphates; Pyrimidines; Research; RNA; Succinates; Uracil

1964
AN ATTEMPT TO FIND PYRIMIDINE INHIBITORS OF A MAMMALIAN ASPARTATE CARBAMOYLTRANSFERASE.
    Biochimica et biophysica acta, 1964, May-04, Volume: 85

    Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Isotopes; Colorimetry; Cytosine Nucleotides; Enzyme Inhibitors; Erythrocytes; Nucleosides; Nucleotides; Pyrimidines; Rabbits; Research; Thymidine; Thymine; Tissue Extracts; Transferases; Uracil Nucleotides

1964
EARLY CHANGES IN PYRIMIDINE BIOSYNTHESIS AFTER PARTIAL HEPATECTOMY.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Aspartic Acid; Carbamates; Carbon Dioxide; Carboxy-Lyases; Chromatography; Dactinomycin; Glucosyltransferases; Hepatectomy; Ligases; Liver Regeneration; Metabolism; Oxidoreductases; Phosphotransferases; Pyrimidines; Rats; Research; RNA; Transferases; Uracil Nucleotides

1965
The synthesis of the pyrimidine ring from 1-carbamylaspartic acid in excised blades of wheat seedlings.
    Acta biochimica Polonica, 1960, Volume: 7

    Topics: Aspartic Acid; Pyrimidines; Seedlings; Triticum

1960
Study of ureidosuccinic acid and related compounds in pyrimidine synthesis by Lactobacillus bulgaricus 09.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 79, Issue:4

    Topics: Aspartic Acid; Lactobacillus; Orotic Acid; Pyrimidines; Urea

1952
Autophagy suppresses tumor progression by limiting chromosomal instability.
    Genes & development, 2007, Jun-01, Volume: 21, Issue:11

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Autophagy; Autophagy-Related Protein 5; Beclin-1; Blotting, Western; Cells, Cultured; Centrosome; Chromosomal Instability; Chromosome Aberrations; Disease Progression; DNA Damage; Epithelial Cells; Fluorescent Antibody Technique; Kidney; Loss of Heterozygosity; Metabolism; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neoplasms; Phosphonoacetic Acid; Ploidies; Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Signal Transduction

2007
DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Apr-29, Volume: 105, Issue:17

    Topics: Aspartic Acid; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 1; DNA; DNA Damage; DNA-Binding Proteins; Humans; Models, Biological; Nucleotides; Phosphonoacetic Acid; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyrimidines; S Phase; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2008
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
    Nature, 2015, Nov-19, Volume: 527, Issue:7578

    Topics: Animals; Argininosuccinate Synthase; Aspartate Carbamoyltransferase; Aspartic Acid; Calcium-Binding Proteins; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line, Tumor; Cell Proliferation; Citrullinemia; Cytosol; Dihydroorotase; Down-Regulation; Enzyme Activation; Humans; Male; Mice; Mice, SCID; Neoplasms; Organic Anion Transporters; Phosphorylation; Pyrimidines; TOR Serine-Threonine Kinases

2015
Pyrimidine synthesis inhibition enhances cutaneous defenses against antibiotic resistant bacteria through activation of NOD2 signaling.
    Scientific reports, 2018, 06-07, Volume: 8, Issue:1

    Topics: Animals; Aspartic Acid; Bacteria; Dermis; Drug Resistance, Multiple, Bacterial; HEK293 Cells; Humans; Immunity, Innate; Nod2 Signaling Adaptor Protein; Phosphonoacetic Acid; Pyrimidines; Signal Transduction; Skin Diseases, Bacterial; Swine

2018
Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets.
    Gut, 2020, Volume: 69, Issue:1

    Topics: Antiviral Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Dihydroorotase; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Fulvestrant; Gene Silencing; Hepatitis D, Chronic; Hepatitis Delta Virus; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin Resistance; Life Cycle Stages; Loss of Function Mutation; Phosphonoacetic Acid; Pyrimidines; RNA Interference; RNA, Small Interfering; RNA, Viral; Signal Transduction; Virus Replication

2020
Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase.
    Nature communications, 2021, 02-11, Volume: 12, Issue:1

    Topics: Arabidopsis; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Catalytic Domain; Feedback; Models, Molecular; Protein Conformation; Pyrimidines; Uridine Monophosphate

2021
Leishmanial aspartyl-tRNA synthetase: Biochemical, biophysical and structural insights.
    International journal of biological macromolecules, 2020, Dec-15, Volume: 165, Issue:Pt B

    Topics: Aminoacylation; Animals; Aspartate-tRNA Ligase; Aspartic Acid; Cloning, Molecular; Evolution, Molecular; Humans; Hydrogen-Ion Concentration; Leishmania donovani; Mice; Models, Molecular; Nitric Oxide; Open Reading Frames; Protein Conformation; Protozoan Proteins; Pyrimidines; RAW 264.7 Cells; Temperature; THP-1 Cells; Tryptophan

2020
Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor.
    Nature communications, 2021, 04-15, Volume: 12, Issue:1

    Topics: Adult; Aged; Animals; Argininosuccinate Synthase; Aspartic Acid; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Citrulline; Citrullinemia; Enzyme Activators; Female; Gene Knockdown Techniques; Gene Knockout Techniques; HEK293 Cells; Humans; Macrolides; Metabolomics; Mice; Middle Aged; Molecular Docking Simulation; Mutation; Protein Binding; Pyrimidines; Recombinant Proteins; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays

2021
Milk metabolome reveals pyrimidine and its degradation products as the discriminant markers of different corn silage-based nutritional strategies.
    Journal of dairy science, 2022, Volume: 105, Issue:11

    Topics: Animals; Aspartic Acid; Cattle; Diet; Female; Fermentation; Lactation; Medicago sativa; Metabolome; Milk; Nitrogen; Orotic Acid; Purines; Pyridoxal Phosphate; Pyridoxic Acid; Pyrimidines; Rumen; Silage; Vitamins; Zea mays

2022