pyrimidine has been researched along with allopurinol in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Higashino, K; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamakita, J; Yamamoto, T | 1 |
| DAVIDSON, JD; FEIGELSON, P; ROBINS, RK | 1 |
| HALL, AP; HOLLOWAY, VP; SCOTT, JT | 1 |
| GUTMAN, AB; YUE, TF | 1 |
| Akaho, E; Ali, HI; Fujita, T; Nagamatsu, T | 1 |
| Dai, X; Liu, D; Mao, Q; Su, Y; Wang, S; Xu, G; Zhang, B | 1 |
| Bao, Z; Dai, X; Duan, Y; Mao, Q; Wang, S; Yang, Y; Zhang, B | 1 |
| Dai, X; Duan, Y; Gao, J; Lin, F; Mao, Q; Sun, M; Wang, S; Yan, C; Yang, Y; Zhang, B; Zhang, T; Zhao, J | 1 |
1 trial(s) available for pyrimidine and allopurinol
| Article | Year |
|---|---|
Effect of allopurinol and benzbromarone on the concentration of uridine in plasma.
Topics: Adult; Allopurinol; Benzbromarone; Dose-Response Relationship, Drug; Gout; Gout Suppressants; Humans; Male; Middle Aged; Purines; Pyrimidines; Time Factors; Uric Acid; Uricosuric Agents; Uridine; Xanthine Oxidase | 1997 |
7 other study(ies) available for pyrimidine and allopurinol
| Article | Year |
|---|---|
Pyrazolopyrimidines as inhibitors and substrates of xanthine oxidase.
Topics: Azoles; Humans; Oxidoreductases; Pyrimidines; Xanthine Oxidase | 1957 |
4-HYDROXYPYRAZOLO (3,4-D) PYRIMIDINE (HPP) IN THE TREATMENT OF GOUT: PRELIMINARY OBSERVATIONS.
Topics: Blood; Colchicine; Diet; Diet Therapy; Drug Therapy; Enzyme Inhibitors; Geriatrics; Gout; Humans; Probenecid; Purines; Pyrazoles; Pyrimidines; Toxicology; Uric Acid; Urine; Xanthine Oxidase; Xanthines | 1964 |
EFFECT OF ALLOPURINOL (4-HYDROXYPYRAZOLO-(3,4-D)PYRIMIDINE) ON SERUM AND URINARY URIC ACID IN PRIMARY AND SECONDARY GOUT.
Topics: Allopurinol; Arthritis; Blood; Bone Marrow Diseases; Drug Therapy; Enzyme Inhibitors; Fluids and Secretions; Gout; Humans; Metabolism; Pharmacology; Polycythemia Vera; Pyrazoles; Pyrimidines; Toxicology; Uric Acid; Uricosuric Agents; Urinary Calculi; Urine; Xanthine Oxidase | 1964 |
A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors.
Topics: Animals; Catalytic Domain; Cattle; Enzyme Inhibitors; Models, Molecular; Protein Binding; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Xanthine Oxidase | 2010 |
Design, synthesis and biological evaluation of 2-(4-alkoxy-3-cyano)phenyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives as novel xanthine oxidase inhibitors.
Topics: Animals; Carboxylic Acids; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthine Oxidase | 2019 |
Targeting the subpocket in xanthine oxidase: Design, synthesis, and biological evaluation of 2-[4-alkoxy-3-(1H-tetrazol-1-yl) phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives.
Topics: Animals; Carboxylic Acids; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Female; Hyperuricemia; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthine Oxidase | 2019 |
Synthesis and biological evaluation of 2-(4-alkoxy-3-cyano)phenylpyrimidine derivatives with 4-amino or 4-hydroxy as a pharmacophore element binding with xanthine oxidase active site.
Topics: Animals; Catalytic Domain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Models, Molecular; Molecular Structure; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Uric Acid; Xanthine Oxidase | 2021 |