Compounds > pyrimethamine
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pyrimethamine and ps 15

pyrimethamine has been researched along with ps 15 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ager, AL; Bliss, RA; Canfield, CJ; Jacobus, DP; Jensen, NP; Kotecka, BM; Rieckmann, KH; Terpinski, J1
Diaz, DS; Jacobus, DP; Kozar, MP; Milhous, WK; O'Neil, MT; Schiehser, GA; Shearer, TW; Skillman, DR; Smith, PL; Yang, YS1
Hughes, WT; Killmar, JT; Oz, HS1
Brun-Pascaud, M; Chau, F; Derouin, F; Garry, L; Girard, PM; Jacobus, D1

Other Studies

4 other study(ies) available for pyrimethamine and ps 15

ArticleYear
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Animals; Antimalarials; Drug Evaluation, Preclinical; Female; Folic Acid Antagonists; Guanidines; Malaria; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Proguanil; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines

2001
In vitro metabolism of phenoxypropoxybiguanide analogues in human liver microsomes to potent antimalarial dihydrotriazines.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: Animals; Antimalarials; Biguanides; Chromatography, Liquid; Drug Resistance; Folic Acid Antagonists; Humans; In Vitro Techniques; Mass Spectrometry; Microsomes, Liver; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Triazines

2005
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:4

    Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Naphthoquinones; Pentamidine; Pneumocystis Infections; Proguanil; Pyrimethamine; Rats; Sulfadoxine; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1994
Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid Antagonists; Immunosuppression Therapy; Pneumocystis Infections; Proguanil; Pyrimethamine; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase; Toxoplasma; Toxoplasmosis, Animal; Trimethoprim

1996