Page last updated: 2024-08-16

pyrimethamine and mercaptopurine

pyrimethamine has been researched along with mercaptopurine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Wilmanns, W1
Bariliak, IR1
Fischer, J; Jahn, U; Wagner-Jauregg, T1
Frick, PG1

Reviews

1 review(s) available for pyrimethamine and mercaptopurine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for pyrimethamine and mercaptopurine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
[Drug induced megaloblastic anemia].
    Haematology and blood transfusion, 1978, Volume: 21

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates

1978
[Effect of lysosome hydrolases on rat embryos].
    Ontogenez, 1977, Volume: 8, Issue:5

    Topics: Acid Phosphatase; Animals; Antimalarials; Antineoplastic Agents; Benzimidazoles; Deoxyribonucleases; Endonucleases; Epinephrine; Female; Hydrolases; Insulin; Lysosomes; Mercaptopurine; Pregnancy; Pyrimethamine; Rats; Ribonucleases; Teratogens

1977
Treating the nervous system in acute leukemia.
    Lancet (London, England), 1972, Feb-05, Volume: 1, Issue:7745

    Topics: Humans; Leukemia, Lymphoid; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Nervous System Diseases; Nitrosourea Compounds; Pyrimethamine; Remission, Spontaneous; Time Factors

1972
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Azaguanine; Azathioprine; Bacteria; Benzimidazoles; Depression, Chemical; Edema; Enterococcus faecalis; Flufenamic Acid; Fungi; Indomethacin; Lactobacillus; Mefenamic Acid; Mercaptopurine; Oxyphenbutazone; Phenylbutazone; Purines; Pyrimethamine; Rats; Riboflavin; Salicylates; Staphylococcus; Tetracycline; Thioguanine

1970
[Possible applications of antivitamins and antimetabolites in therapy].
    Bibliotheca nutritio et dieta, 1966, Volume: 8

    Topics: Aminopterin; Antimetabolites; Azaserine; Child; Child, Preschool; Choriocarcinoma; Diazooxonorleucine; Female; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Methotrexate; Pregnancy; Pyrimethamine; Toxoplasmosis; Vitamin K; Vitamins

1966