pyrimethamine has been researched along with diazepam in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 15 (71.43) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Carere, A; Conti, G; Conti, L; Crebelli, R | 1 |
| Natarajan, AT | 1 |
| Bassani, B; Leopardi, P; Pacchierotti, F; Zijno, A | 1 |
| Adler, ID | 1 |
| Hartley-Asp, B; Wallin, M | 1 |
| Parry, JM | 1 |
| Parry, EM; Parry, JM; Warr, TJ | 1 |
| Parry, JM; Sors, A | 1 |
| Duivenvoorden, WC; Meijers, M; Natarajan, AT; Zwanenburg, TS | 1 |
| Di Sibio, A; Lomi, A; Sbrana, I; Scarcelli, V | 1 |
| Lynch, AM; Parry, JM | 1 |
| Aardema, MJ; Brauninger, RM; Carr, GJ; Gibson, DP; Kerckaert, GA; LeBoeuf, RA | 1 |
| Barale, R; Barrai, I; Bernacchi, F; Betti, C; Marrazzini, A | 1 |
| Amabeoku, G; Chikuni, O | 1 |
| Bergqvist, Y; Breyer, S; Burgmann, H; Feistauer, S; Feucht, M; Graninger, W; Hellgren, U; Uhl, F; Winkler, S | 1 |
3 review(s) available for pyrimethamine and diazepam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synopsis of the in vivo results obtained with the 10 known or suspected aneugens tested in the CEC collaborative study.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromosome Aberrations; Colchicine; Diazepam; Econazole; Europe; European Union; Hydroquinones; Male; Mice; Micronucleus Tests; Mitotic Index; Mutagenicity Tests; Mutagens; Ploidies; Pyrimethamine; Spermatocytes; Thiabendazole; Thimerosal; Vinblastine | 1993 |
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
Topics: Aneuploidy; Animals; Aspergillus; Cadmium; Cadmium Chloride; Cell Cycle; Cells, Cultured; Chloral Hydrate; Chlorides; Colchicine; Diazepam; Econazole; Environmental Pollutants; Europe; European Union; Hydroquinones; Mammals; Mutagenicity Tests; Mutagens; Pyrimethamine; Salmonella typhimurium; Thiabendazole; Thimerosal; Vinblastine | 1993 |
18 other study(ies) available for pyrimethamine and diazepam
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk | 1977 |
In vitro studies with nine known or suspected spindle poisons: results in tests for chromosome malsegregation in Aspergillus nidulans.
Topics: Aneuploidy; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chromosomes, Fungal; Colchicine; Crossing Over, Genetic; Diazepam; Econazole; Hydroquinones; Mitosis; Pyrimethamine; Spindle Apparatus; Thiabendazole; Thimerosal | 1991 |
An overview of the results of testing of known or suspected aneugens using mammalian cells in vitro.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Cells, Cultured; Chloral Hydrate; Chlorides; Chromosome Aberrations; Colchicine; Cricetinae; Cricetulus; Diazepam; Econazole; Fibroblasts; Humans; Hydroquinones; Lymphocytes; Micronucleus Tests; Mitosis; Mutagenicity Tests; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vinblastine | 1993 |
In vivo studies on chemically induced aneuploidy in mouse somatic and germinal cells.
Topics: Aneuploidy; Animals; Bone Marrow; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine; Diazepam; Econazole; Hydroquinones; Male; Mice; Mice, Inbred Strains; Micronucleus Tests; Mutagenicity Tests; Mutagens; Ploidies; Pyrimethamine; Spermatocytes; Testis; Thiabendazole; Thimerosal | 1993 |
Effects of potential aneuploidy inducing agents on microtubule assembly in vitro.
Topics: Aneuploidy; Animals; Brain; Cadmium; Cadmium Chloride; Cattle; Chloral Hydrate; Chlorides; Colchicine; Diazepam; Econazole; Hydroquinones; Microtubule Proteins; Microtubules; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vinblastine | 1993 |
An evaluation of the use of in vitro tubulin polymerisation, fungal and wheat assays to detect the activity of potential chemical aneugens.
Topics: Aneuploidy; Animals; Aspergillus nidulans; Cadmium; Cadmium Chloride; Chloral Hydrate; Chlorides; Colchicine; Diazepam; Econazole; Fungi; Hydroquinones; Mammals; Microtubules; Mutagenicity Tests; Mutagens; Pyrimethamine; Saccharomyces cerevisiae; Thiabendazole; Thimerosal; Triticum; Tubulin; Vinblastine | 1993 |
A comparison of two in vitro mammalian cell cytogenetic assays for the detection of mitotic aneuploidy using 10 known or suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrate; Chlorides; Colchicine; Cricetinae; Cricetulus; Diazepam; Econazole; Hydroquinones; Karyotyping; Mutagenicity Tests; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vinblastine | 1993 |
Induction of mitotic aneuploidy using Chinese hamster primary embryonic cells. Test results of 10 chemicals.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Colchicine; Cricetinae; Cricetulus; Diazepam; Dose-Response Relationship, Drug; Econazole; Embryo, Mammalian; Female; Hydroquinones; Male; Mitosis; Mutagenicity Tests; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vincristine | 1993 |
C-mitosis and numerical chromosome aberration analyses in human lymphocytes: 10 known or suspected spindle poisons.
Topics: Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromosome Aberrations; Colchicine; Diazepam; Diploidy; Dose-Response Relationship, Drug; Econazole; Humans; Hydroquinones; Lymphocytes; Mitosis; Mutagenicity Tests; Mutagens; Ploidies; Polyploidy; Pyrimethamine; Spindle Apparatus; Thiabendazole; Thimerosal; Vinblastine | 1993 |
The cytochalasin-B micronucleus/kinetochore assay in vitro: studies with 10 suspected aneugens.
Topics: Aneuploidy; Animals; Cadmium; Cadmium Chloride; Cell Division; Cell Line; Centromere; Chloral Hydrate; Chlorides; Colchicine; Cricetinae; Cricetulus; Cytochalasin B; Diazepam; Dose-Response Relationship, Drug; Econazole; Humans; Hydroquinones; Micronucleus Tests; Mitomycin; Mutagens; Pyrimethamine; Thiabendazole; Thimerosal; Vinblastine | 1993 |
Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay.
Topics: Aneuploidy; Animals; Asbestos; Benomyl; Cadmium; Cadmium Chloride; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Chloral Hydrate; Chlorides; Cricetinae; Demecolcine; Diazepam; Diethylstilbestrol; Econazole; Embryo, Mammalian; Evaluation Studies as Topic; Griseofulvin; Mesocricetus; Pyrimethamine; Thiabendazole | 1995 |
Micronucleus test and metaphase analyses in mice exposed to known and suspected spindle poisons.
Topics: Animals; Bone Marrow Cells; Cadmium; Cadmium Chloride; Cells, Cultured; Chloral Hydrate; Chlorides; Chromosome Aberrations; Colchicine; Diazepam; Econazole; Hydroquinones; Male; Metaphase; Mice; Micronucleus Tests; Pyrimethamine; Spindle Apparatus; Thiabendazole; Thimerosal; Vinblastine | 1994 |
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice.
Topics: Animals; Bicuculline; Diazepam; Dopamine; Drug Interactions; gamma-Aminobutyric Acid; Levodopa; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Pyrimethamine; Seizures | 1994 |
[Mefloquine and sulfadoxine/pyrimethamine overdose in malaria tropica].
Topics: Adult; Diazepam; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Haloperidol; Humans; Malaria, Falciparum; Male; Mefloquine; Psychoses, Substance-Induced; Pyrimethamine; Sulfadoxine; Thioridazine | 1993 |