pyrimethamine has been researched along with chloroquine in 1049 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 426 (40.61) | 18.7374 |
| 1990's | 141 (13.44) | 18.2507 |
| 2000's | 303 (28.88) | 29.6817 |
| 2010's | 153 (14.59) | 24.3611 |
| 2020's | 26 (2.48) | 2.80 |
| Authors | Studies |
|---|---|
| Elslager, EF; Hutt, MP; Jacob, P; Johnson, J; Rane, L; Temporelli, B; Werbel, LM; Worth, DF | 1 |
| Genther, CS; Smith, CS | 1 |
| Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P | 1 |
| Ager, AL; Bliss, RA; Canfield, CJ; Jacobus, DP; Jensen, NP; Kotecka, BM; Rieckmann, KH; Terpinski, J | 1 |
| Jomaa, H; Kettler, K; Schlitzer, M; Wiesner, J | 1 |
| Jomaa, H; Krämer, O; Mitsch, A; Schlitzer, M; Wiesner, J; Wissner, P | 1 |
| Jomaa, H; Kettler, K; Ortmann, R; Sakowski, J; Schlitzer, M; Wiesner, J | 1 |
| Fucik, K; Jomaa, H; Kettler, K; Ortmann, R; Sakowski, J; Schlitzer, M; Wiesner, J | 1 |
| Jomaa, H; Mitsch, A; Schlitzer, M; Wiesner, J | 1 |
| Bauer, KD; Bendale, P; Buckner, FS; Chakrabarti, D; Floyd, D; Gelb, MH; Hamilton, A; Hornéy, CP; Lombardo, LJ; Nallan, L; Pendyala, PR; Rivas, K; Sebti, S; Van Voorhis, WC; Weber, PC; Williams, DK; Windsor, WT; Yokoyama, K | 1 |
| Baniecki, ML; Clardy, J; Wirth, DF | 1 |
| Dennull, RA; Gerena, L; Johnson, JD; Lopez-Sanchez, M; Roncal, NE; Waters, NC | 1 |
| Bongard, E; Brown, DM; Loakes, D; Too, K; Vivas, L; Yardley, V | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y | 1 |
| Lee, SJ; Moon, HI; Park, WH | 1 |
| Awasthi, SK; Bhasin, VK; Bhattacharya, A; Mishra, LC; Sharma, M | 1 |
| Masseno, V; Muriithi, S; Nzila, A | 1 |
| Azas, N; Castera-Ducros, C; Dumètre, A; Gasquet, M; Hutter, S; Laget, M; Rathelot, P; Rault, S; Reboul, JP; Vanelle, P; Verhaeghe, P | 1 |
| Alvarez-Doval, A; Angulo-Barturen, I; Gargallo-Viola, D; Garuti, H; Gómez, V; Ibáñez, J; Jiménez-Díaz, MB; Martínez, A; Mulet, T; Shultz, LD; Viera, S | 1 |
| Azas, N; Dumètre, A; Gellis, A; Hutter, S; Kabri, Y; Laget, M; Vanelle, P; Verhaeghe, P | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Brun, R; Chitnumsub, P; Dartois, V; Diagana, TT; Goh, A; Kamchonwongpaisan, S; Keller, TH; Kiara, SM; Lakshminarayana, SB; Ma, NL; Maneeruttanarungroj, C; Nzila, A; Rottmann, M; Taweechai, S; Weaver, M; Wittlin, S; Wong, J; Yeung, BK; Yuthavong, Y; Zou, B | 1 |
| Beck, HP; Brun, R; Cohen, SB; Dartois, V; Dharia, NV; Diagana, TT; Fidock, DA; Goh, A; González-Páez, GE; Jegla, T; Keller, TH; Lakshminarayana, SB; Lee, MC; McNamara, C; Nosten, F; Plouffe, DM; Renia, L; Rottmann, M; Russell, B; Schmitt, EK; Seitz, P; Spencer, KR; Suwanarusk, R; Tan, J; Winzeler, EA; Yeung, BK; Zou, B | 1 |
| Bhattacharjee, AK; Gerena, L; Gutteridge, CE; Hoffman, MM; Milhous, WK | 1 |
| Bathurst, I; Buckner, FS; Burrows, J; Charman, SA; Charman, WN; Creason, S; Deng, X; El Mazouni, F; Floyd, DM; Gujjar, R; Matthews, D; Phillips, MA; Rathod, PK; Shackleford, DM; White, J; White, KL | 1 |
| Charman, SA; Chibale, K; Fakorede, F; Gessner, RK; Gitari, PW; Hudson, A; Kaiser, M; Ndakala, AJ; October, N; Shackleford, DM; White, KL; Yeates, C | 1 |
| Ang, HQ; Borboa, R; Brun, R; Caldwell, C; Chang, J; Chatterjee, AK; Chen, Z; Dartois, V; Diagana, T; Ek, J; Fischli, C; Francek, C; Gagaring, K; Glynne, R; Goh, A; Hollenbeck, T; Isbell, J; Kang, ML; Keller, T; Kuhen, K; Lakshminarayana, SB; Li, C; Lin, X; Liu, F; Nagle, A; Plouffe, D; Rottmann, M; Skolnik, S; Tan, M; Tan, W; Tully, DC; Tuntland, T; Wang, J; Winzeler, E; Wu, J; Wu, T; Ye, N; Zeng, P | 1 |
| Azas, N; Castera-Ducros, C; Dumètre, A; Garrigue, P; Hutter, S; Laget, M; Mbatchi, L; Rathelot, P; Rault, S; Remusat, V; Sifredi, F; Vanelle, P; Verhaeghe, P | 1 |
| Azas, N; Castera-Ducros, C; Dumètre, A; Fersing, C; Hutter, S; Laget, M; Prieri, M; Rathelot, P; Rault, S; Sifredi, F; Vanelle, P; Verhaeghe, P; Yzombard, J | 1 |
| Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y | 1 |
| Azas, N; Casanova, M; Castera-Ducros, C; Dumètre, A; Hutter, S; Kraiem-M'rabet, M; Laget, M; Mbatchi, L; Paloque, L; Rathelot, P; Rault, S; Remusat, V; Vanelle, P; Verhaeghe, P | 1 |
| Breytenbach, WJ; de Kock, C; N'Da, DD; Pretorius, SI; Smith, PJ | 1 |
| Biamonte, MA; Le Roch, KG; Wanner, J | 1 |
| Avery, VM; Sykes, ML | 1 |
| Burrows, J; Calderón, F; de la Rosa, JC; Fernández, E; Gamo, FJ; Jiménez-Díaz, MB; Mulet, T; Prats, S; Solana, J; Vidal-Mas, J; Witty, M | 1 |
| Khan, SI; Manohar, S; Rajesh, UC; Rawat, DS; Tekwani, BL | 1 |
| Angulo-Barturen, I; Avery, VM; Awasthy, D; Balasubramanian, V; Bandodkar, B; Barde, SP; Bharath, S; Chinnapattu, M; Duffy, S; Ferrer, S; Gamo, FJ; Hameed P, S; Hosagrahara, V; Iyer, PS; Jatheendranath, S; Jiménez-Díaz, MB; Kavanagh, S; Koushik, K; Lukens, AK; Magistrado, PA; Manjrekar, P; Martínez, MS; Morayya, S; Mukherjee, K; Narayan, C; Narayanan, S; Panduga, V; Patil, V; Prabhakar, KR; Raichurkar, A; Ramachandran, S; Rautela, N; Reddy, J; Rudrapatna, SS; Sambandamurthy, VK; Sanz, LM; Saralaya, R; Shanbag, G; Sinha, A; Srivastava, A; Viswanath, P; Waterson, D; Wirth, DF | 1 |
| Achar, V; Angulo-Barturen, I; Avery, VM; Awasthy, D; Bharath, S; Coburn-Flynn, O; Duffy, S; Ferrer, S; Fidock, DA; Gamo, FJ; Hameed P, S; Hosagrahara, V; Iyer, PS; Jiménez-Díaz, MB; Kavanagh, S; Lee, MC; Martínez, MS; Menasinakai, S; Morayya, S; Nanduri, R; Narayanan, S; Panduga, V; Prabhakar, KR; Raichurkar, A; Ramachandran, S; Rautela, N; Reddy, J; Sambandamurthy, VK; Sanz, LM; Saralaya, R; Shanbhag, G; Srivastava, A; Waterson, D | 1 |
| Khan, SI; Kumar, D; Ponnan, P; Rawat, DS; Tekwani, BL | 1 |
| Chinnapattu, M; Iyer, PS; Sathiyanarayanan, KI | 1 |
| Iyer, PS; Kannan, M; Khan, FR; Raichurkar, AV | 1 |
| Azas, N; Basmaciyan, L; Cohen, A; Crozet, MD; Dallemagne, P; Deharo, E; Dumètre, A; Hutter, S; Laget, M; Lancelot, JC; Lesnard, A; Lorthiois, A; Mazier, D; Paloque, L; Rathelot, P; Rault, S; Sibley, CH; Suzanne, P; Valentin, A; Vanelle, P; Verhaeghe, P | 1 |
| Aguilar-Suárez, R; Correa-Basurto, J; Galindo-Sevilla, N; Hernández-Luis, F; Márquez-Navarro, A; Mendoza-Martínez, C; Montero-Cortes, MD; Nieto-Meneses, R; Nogueda-Torres, B; Rodriguez-Lezama, A; Rojas-Rojas, Á; Suárez-Contreras, E | 1 |
| Ballell-Pages, L; Calderón, F; Castañeda-Casado, P; Crespo-Fernández, B; de las Heras-Dueña, L; Guijarro-López, L; Huertas-Valentín, L; Jiménez-Díaz, MB; Keurulainen, L; Kiuru, P; Leino, TO; Martínez-Martínez, MS; Puente-Felipe, M; Sandoval-Izquierdo, E; Sanz, LM; Siiskonen, A; Vahermo, M; Viera, S; Yli-Kauhaluoma, J | 1 |
| Angulo-Barturen, I; Bashyam, S; Birkholtz, LM; Botha, M; Brunschwig, C; Chibale, K; Churchyard, A; Coetzer, TL; Dhinakaran, R; Ferrer, S; Gonzàlez Cabrera, D; Han, Z; Jiménez-Díaz, MB; Lauterbach, S; Le Manach, C; Meister, S; Njoroge, M; Paquet, T; Reader, J; Santos Martínez, M; Street, LJ; Taylor, D; Waterson, D; Winzeler, EA; Wittlin, S; Witty, MJ | 1 |
| Avery, V; Derese, S; Deyou, T; Duffy, S; Erdélyi, M; Fitzpatrick, PA; Gruhonjic, A; Gumula, I; Heydenreich, M; Holleran, J; Landberg, G; Mumo, M; Pang, F; Rissanen, K; Yenesew, A | 1 |
| Cheenpracha, S; Jaidee, A; Kamchonwongpaisan, S; Laphookhieo, S; Promchai, T; Pyne, SG; Rattanajak, R; Ritthiwigrom, T; Trisuwan, K | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Avery, VM; Duffy, S; Khalaf, AI; Scott, FJ; Suckling, CJ | 1 |
| Campbell, S; Charman, SA; Chen, G; Dias, LC; Krake, SH; Martinez, PDG; McLaren, J; Ryan, E; White, K; Willis, P | 1 |
| Bahuguna, A; Khan, SI; Kumar, D; Maurya, SS; Rawat, DS | 1 |
| Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS; Patel, UH; Vanparia, SF | 1 |
| Bahuguna, A; Khan, SI; Kholiya, R; Rawat, DS; Tripathi, M | 1 |
| Avery, VM; Carroll, AR; Duffy, S; Senadeera, SPD | 1 |
| Doshi, H; Ray, A; Thakkar, SS; Thakor, P | 1 |
| Berry, P; Campo, B; Cao, J; Ciaravino, V; Easom, EE; Erve, JCL; Freund, YR; Gamo, FJ; Guo, D; Jacobs, RT; Plattner, JJ; Rosenthal, PJ; Sanz, LM; Zhang, YK | 1 |
| Doshi, H; Ray, A; Thakkar, SS; Thakkar, VR; Thakor, P | 1 |
| Bhatt, JD; Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS; Patel, UH; Vanparia, SF | 1 |
| Arrizabalaga, G; Fargnoli, L; Khan, SI; Labadie, GR; Panozzo-Zénere, EA; Porta, EOJ; Tekwani, BL | 1 |
| Avery, VM; Carroll, AR; Duffy, S; Robertson, LP; Wang, D; Wang, Y | 1 |
| Aguiar, ACC; Berlinck, RGS; Bertonha, AF; Costa, TR; de Souza, GE; Ferreira, AG; Gadelha, FR; Grazzia, N; Guido, RVC; Hajdu, E; Miguel, DC; Oliva, G; Parra, LLL; Romo, D; Severo, IRM | 1 |
| Chen, PB; Fuchter, MJ; Li, F; Lubin, AS; Lueg, GA; Malmquist, NA; Scherf, A; Sundriyal, S; Vedadi, M; White, AJP | 1 |
| Aguiar, ACC; Correia, CRD; Costa, JL; de Souza, GE; Garcia, CRS; Garcia, ML; Guido, RVC; Nakabashi, M; Oliva, G; Panciera, M; Simão Dos Santos, EF; Singh, MK | 1 |
| Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Senadeera, SPD | 1 |
| Avery, VM; Butler, GS; Drinkwater, N; Duffy, S; Grin, PM; Kassiou, M; Lucantoni, L; Malcolm, TR; McGowan, S; Overall, CM; Scammells, PJ; Vinh, NB | 1 |
| Aguiar, ACC; de Souza, JO; Fagundez, C; Gamo, FJ; Guido, RVC; Ottilie, S; Peña, S; Sanz, LM; Scarone, L; Sellanes, D; Serra, GL; Stewart, L; Winzeler, EA; Yardley, V | 1 |
| Avery, VM; Carroll, AR; Duffy, S; Lucantoni, L; Robertson, LP | 1 |
| Bhatt, JD; Chudasama, CJ; Dixit, BC; Dixit, RB; Patel, BD; Patel, TS | 1 |
| Buckner, FS; Cal, M; Davis, PH; Kaiser, M; Lepesheva, GI; Sanford, AG; Vennerstrom, JL; Wallick, AI; Wang, X | 1 |
| Cheong, SL; Ng, CH; Tibon, NS | 1 |
| Avery, VM; Duffy, S; Erdélyi, M; Lindblad, S; Maeda, G; Munissi, JJE; Nyandoro, SS; Pelletier, J | 1 |
| Adhikari, N; Gaikwad, VR; Govindarajalu, G; Karale, UB; Krishna, EV; Krishna, VS; Misra, S; Rode, HB; Sijwali, PS; Sriram, D | 1 |
| Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G | 1 |
| Akao, Y; Avery, VM; Charman, SA; Chen, G; Chen, X; Chiu, FCK; Cho, N; Crespo, B; Dechering, KJ; Duffy, S; Kamaura, M; Katneni, K; Laleu, B; Lucantoni, L; Ochida, A; Sanz, LM; Shackleford, DM; Sturm, A; Wang, B; White, KL; Wittlin, S | 1 |
| Golenser, J; Meuwissen, JH; Verhave, JP | 1 |
| Beale, GH; Hall, R; Rosario, VE; Walliker, D | 1 |
| Schmidt, LH | 4 |
| Crosby, R; Rasco, J; Schmidt, LH; Vaughan, D | 1 |
| Ebizawa, I | 1 |
| Cambournac, FJ | 1 |
| Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T | 1 |
| Hlaing, N; Tin, F | 1 |
| Bruce-Chwatt, LJ | 5 |
| Black, RH; Ray, AP | 1 |
| Duursma, SA | 1 |
| Carson, PE; Frischer, H; Rieckmann, KH; Trenholme, GM; Williams, RL | 2 |
| Maier, W; Piekarski, G | 1 |
| Ponnampalam, JT | 2 |
| Cowie, RL | 1 |
| Bentley, SJ | 1 |
| Chongsuphajaisiddhi, T; Harinasuta, T; Puangpartk, S; Subchareon, A | 1 |
| Ferraroni, JJ; Hayes, J | 1 |
| Maples, BK; Richards, WH | 1 |
| Eke, RA | 1 |
| Ebisawa, I; Muto, T; Tanabe, S | 1 |
| Barkakuty, BN; Pattanayak, S; Phukan, D; Roy, RG | 1 |
| Pattanayak, S; Roy, RG; Sen, N | 1 |
| Amin, NM | 1 |
| Ecker, A; Várnai, F | 1 |
| Gill, F; Miller, LH; Neva, FA | 1 |
| Clyde, DF; Hornick, RB; McCarthy, VC; Miller, RM | 1 |
| Dondero, TJ; Parsons, RE; Ponnampalam, JT | 1 |
| Ponnampalam, JT; Roy, OS; Seow, CL | 1 |
| Baerg, DC; Rossan, RN; Young, MD | 1 |
| Rollo, IM | 1 |
| Fernex, M | 2 |
| Agnes, E; Ferenc, V | 1 |
| Hall, AP; Pearlman, EJ | 1 |
| Lewis, AN; Ponnampalam, JT | 1 |
| Ryan, BP | 1 |
| Ebisawa, I; Fukuyama, T | 1 |
| Cockcroft, CR; du Preez, O | 1 |
| Frood, JD; Harland, PS; Parkin, JM | 1 |
| Garber, G; Thind, J | 1 |
| Ghosh, SK; Sharma, VP; Yadav, RS | 1 |
| Bunnag, D; Chindanond, D; Chittamas, S; Fernex, M; Harinasuta, T; Kristiansen, S; Malikul, S; Mittelholzer, ML; Sturchler, D | 1 |
| Adio, RA; Dickschat, U; Mittelholzer, ML; Reber-Liske, R; Salako, LA; Sowunmi, A; Stürchler, D; Walker, O | 1 |
| Basco, LK; Charmot, G; Cremer, G; Le Bras, J | 1 |
| Ikeda, I; Kamiyama, T; Matsubara, J; Niinuma, S | 1 |
| Tanaka, M | 1 |
| Chutmongkonkul, M; Maier, WA; Seitz, HM | 2 |
| Havlik, I; Monteagudo, FS; van Zyl, RL | 1 |
| Nzala, S; Puta, C; Sijumbila, G | 1 |
| Bunnag, D; Chitamas, S; Harinasuta, T; Karbwang, J; Viravan, C | 1 |
| Ameh, JO; Daniel, HI; Gadzama, NM; Molta, NB; Oguche, SO; Otu, TI; Watila, IM | 1 |
| Brandling-Bennett, AD; Kamsteeg, H; Keuter, M; Khalumi, G; Ngwawe, W; Ronday, M; Sanders, J; Schouten, E; Veltkamp, S; Wetsteyn, JC | 1 |
| Breman, JG; Koplan, JP; McFarland, D; Sudre, P | 1 |
| Salako, LA; Sowunmi, A | 1 |
| Chen, C; Zheng, X | 1 |
| Freese, JA; Golenser, J; Markus, MB | 1 |
| Irare, SG; Lemnge, MM; Mhina, JI | 1 |
| Dua, VK; Sharma, SK; Sharma, VP | 1 |
| Carme, B | 1 |
| Baird, JK; Bangs, MJ; Basri, H; Jones, TR; Ritonga, A | 1 |
| Boudreau, EF; Chaikummao, S; Pang, LW; Witayarut, C | 1 |
| Gardner, A; Nevill, CG | 1 |
| Ejezie, GC; Emeribe, AO; Ezedinachi, EN | 1 |
| Bourdeau, EF; Childs, GE; Milhous, WK; Pang, L; Wimonwattratee, T | 1 |
| Prasad, H; Prasad, RN; Sharma, VP; Virk, KJ | 1 |
| Fujimura, K; Fujioka, H; Fujita, M; Kato, N; Nishiyama, Y | 1 |
| Domínguez-Corrales, MV; Regordan, C; Sánchez-Porto, A | 1 |
| Hopfenmüller, W; Janitschke, K; Schultes, U; Weber, G; Weinke, T | 1 |
| Eberlé, F; Gazin, P; Gelas, H; Hengy, C; Jambou, R; Kouka-Bemba, D | 1 |
| Mjönes, S | 1 |
| Alaribe, AA; Ezedinachi, EN; Gemade, EI; Ikpatt, NW; Usanga, EA | 1 |
| Björkman, A; Ericsson, O; Warsame, M; Wernsdorfer, WH | 1 |
| Brandling-Bennett, AD; Hoogstrate, M; Keuter, M; Ngwawe, WA; Raasveld, M; van de Ree, M; van Eijk, A; Watkins, WM; Were, JB | 1 |
| Brandicourt, O; Carme, B; Gay, F; Gentilini, M; Le Bras, J; Mbitsi, A; Moudzeo, H; Ndounga, M; Sathounkazi, C | 1 |
| Dinis, DV; Schapira, A | 1 |
| Brun, R; Franklin, RM; Grieder, A | 1 |
| Fasunon, OD; Uwaifo, AO | 1 |
| Kano, S; Matsuoka, Y; Obana, M; Suzuki, M; Waki, S; Yamakawa, H | 1 |
| Adetoro, O; Akintunde, A; Alakija, T; Breman, JG; Edungbola, LD; Nahlen, BL; Nguyen-Dinh, P; Ogunbode, O | 1 |
| Davis, DR; Hutton, DC; Rieckmann, KH | 1 |
| Gu, HM; Inselburg, J | 1 |
| Jirsa, M; Kaláb, M; Kordac, V; Kotal, P | 1 |
| Disu, MM; Kalonji, MW; Mbudi, PK; Pela, NN | 1 |
| Cervinka, J; Jirsa, M; Kaláb, M; Kordac, V; Kotal, P; Martásek, P | 1 |
| Saxena, BN; Sharma, VP; Shukla, MM; Singh, N | 1 |
| Hansford, CF | 1 |
| Belec, L; Bouree, P; Delmont, J; Georges, AJ; Quenum, B; Testa, J | 1 |
| Ndumbe, PM | 1 |
| Aina Adio, R; Fadeke Aderounmu, A; Laoye, AJ; Modupe Makinde, J; Salako, LA | 1 |
| Bunnag, D; Harinasuta, T; Lasserre, R; Leimer, R; Vinijanont, S | 1 |
| Campbell, CC; Lobel, HO; Miller, KD; Papaioanou, M; Rombo, L; Stenbeck, J | 1 |
| Somaini, B; Steffen, R | 1 |
| Edstein, MD; O'Donoghue, M; Rieckmann, KH; Veenendaal, JR | 1 |
| Mutambu, SL; Taylor, P | 1 |
| Bradley, AK; Byass, P; Greenwood, AM; Greenwood, BM; Hayes, RJ; N'Jie, AB; Snow, RW | 1 |
| Kollaritsch, H; Kollaritsch, R; Kremsner, P; Leimer, R; Mailer, H; Stemberger, H; Wiedermann, G | 1 |
| Hönigsmann, H; Ortel, B; Sivayathorn, A | 1 |
| Barrington, P; Harper, JI; Langtry, JA; Staughton, RC | 1 |
| Campbell, CC; Kuritsky, JN; Lobel, HO; Miller, KD; Satriale, RF; Stern, R | 1 |
| Shao, BR; Ye, XY | 1 |
| Adkins, KF; Barber, MT; Savage, NW | 1 |
| Cai, XZ; Fu, SG; Huang, JK; Huang, OL; Ouyang, WC; Pang, XJ; Wang, XF; Wu, Z; Zhang, KY; Zhou, JX | 1 |
| Brubaker, G; Draper, CC; Hills, M; Kilimali, VA | 1 |
| Doi, H; Ishii, A; Shimono, K | 1 |
| Druilhe, P; Gentilini, M; Stahel, E | 1 |
| Birk, O; Golinski, M; Sack, J | 1 |
| Heap, BJ | 1 |
| Dastych, P; Giboda, M; Vanista, J | 1 |
| Beltzner, B; Kupferschmidt, HG; Schröder, K | 1 |
| Aderounmu, AF; Adio, RA; Laoye, JO; Makinde, JM; Salako, LA | 1 |
| Cai, XZ; Fu, SG; Huang, JK; Huang, QL; Huang, XF; Pan, XJ; Quyang, WC; Wu, Z; Zhang, KY; Zhou, JX | 1 |
| Rolfe, M | 1 |
| Osanai, CH; Passos, AD; Reyes, S | 1 |
| Bygbjerg, IC; Fogh, S; Gøtzsche, PC; Jepsen, S; Kuijlen, K; Mordhorst, CH; Ravn, P; Rønn, A; Schapira, A | 1 |
| Phillips-Howard, PA; Warwick Buckler, J | 1 |
| Childs, GE; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Boudreau, EF; Chen, C; Childs, GE; Häusler, B; Milhous, W; Pooyindee, N; Wimonwattrawatee, T | 1 |
| Bugilimfura, L; Deloron, P; Neill, M; Ntilivamunda, A; Sexton, JD | 1 |
| Bugilimfura, L; Deloron, P; Sexton, JD; Sezibera, C | 1 |
| Burchard, GD; Winkler, E | 1 |
| Schapira, A; Schwalbach, JF | 1 |
| Beltzner, BE; Kupferschmidt, HG; Schröder, K | 1 |
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| D'Alessandro, U; Egwang, TG; Hastings, IM; Langi, P; Mutabingwa, TK; Speybroeck, N; Talisuna, AO; Van Marck, E; Watkins, WW | 1 |
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| CARRESCIA, PM; RAFFAELE, G | 1 |
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| CONTACOS, PG; MILLAR, JW; STITCHER, JE; YOUNG, MD | 1 |
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| EYLES, DE; HOO, CC; SANDOSHAM, AA; WARREN, M | 1 |
| COLLINS, WE; JEFFERY, GM; SKINNER, JC | 2 |
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| COATNEY, GR; CONTACOS, PG; LUNN, JS | 1 |
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| MCGREGOR, IA | 1 |
| CAMPBELL, JM; COETZER, AJ | 1 |
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| EYLES, DE; MONTGOMERY, R; SANDOSHAM, AA | 1 |
| MEUWISSEN, JH | 2 |
| ROBERTS, JM | 1 |
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| LEGTERS, LJ; POLLACK, S; POWELL, RD; WALLACE, DK | 1 |
| ALVING, AS; BREWER, GJ; DEGOWIN, RL; POWELL, RD | 1 |
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| Cox-Singh, J; Davis, TM; Doan, HN; Hewitt, S; Le, DC; Nguyen, MH; Nguyen, TH; Tran, BK; Tran, QT; Vo, NP | 1 |
| Björkman, A; Hugosson, E; Montgomery, SM; Premji, Z; Tarimo, D; Troye-Blomberg, M | 1 |
| Anderson, TJ; Balkan, S; Jacobzone, C; Nair, S; Zavai, A | 1 |
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| Anderson, TC; Brockman, A; Chakma, S; Nair, S; Talukder, L; van den Broek, IV; van der Wardt, S | 1 |
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| Annerberg, A; Barends, M; Keola, S; Khanthavong, M; Lindegårdh, N; Mayxay, M; Newton, PN; Phetsouvanh, R; Phompida, S; Pongvongsa, T; White, NJ; Yapom, R | 1 |
| Adedeji, AA; Babalola, CP; Fateye, BA; Sowunmi, A | 1 |
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| Adam, I; Ahmed, GI; Elbashir, MI; Elghzali, G; Gustafssons, LL; Osman, ME | 1 |
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| Coulibaly, D; Doumbo, O; Doumtabe, D; Kayentao, K; Keita, AS; Kodio, M; Maiga, B; Maiga, H; Mungai, M; Newman, RD; Ongoiba, A; Parise, ME | 1 |
| Ariey, F; Bedja, SA; Mercereau-Puijalon, O; Migliani, R; Raherinjafy, RH; Randrianarivelojosia, M | 1 |
| Ariey, F; Domarle, O; Paul, RE; Robert, V; Sokhna, CS; Talman, AM; Trape, JF | 1 |
| Dokomajilar, C; Dorsey, G; Kamya, MR; Kiggundu, M; Rosenthal, PJ; Staedke, SG | 1 |
| Baerwaldt, T; Checchi, F; Danks, A; Durand, R; Heinzelmann, A; Hora, B; Kamara, S; Lamotte, Nd; Morineau, G; Oloo, A; Pinoges, L; Ranford-Cartwright, L; Roddy, P; Smet, M; Williams, A; Wurie, AR | 1 |
| Browne, EN; Eggelte, TA; Evans, J; Flessner, C; Horstmann, RD; Marks, F; May, J; Meyer, CG; von Kalckreuth, V | 1 |
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| Adam, I; Elbashir, MI; Himeidan, YE; Malik, EM; Mohammed, MM; Salah, MT | 1 |
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| Alexander, N; Coleman, R; Drakeley, CJ; Dunyo, S; Jawara, M; Ord, R; Pinder, M; Sutherland, CJ; Targett, GA; Walraven, G | 1 |
| Babiker, H; Hunt, P; Walliker, D | 1 |
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| Göbels, K; Graupner, J; Grobusch, MP; Häussinger, D; Lund, A; Richter, J | 1 |
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| Bakyaita, N; Banek, K; Dorsey, G; Kamya, MR; Kilian, A; Kironde, F; Nsobya, S; Reingold, A; Rosenthal, PJ; Staedke, SG; Talisuna, A; Wabwire-Mangen, F; Yeka, A | 1 |
| Djalle, D; Koula, MR; Madji, N; Manirakiza, A; Menard, D; Talarmin, A | 1 |
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| Anderson, TJ; Guthmann, JP; Mayxay, M; Nair, S; Nash, D; Newton, PN; Nosten, F | 1 |
| Bakyaita, N; Banek, K; Dorsey, G; Kamya, MR; Kilian, A; Kironde, F; Nsobya, SL; Reingold, A; Rosenthal, PJ; Slater, M; Staedke, SG; Talisuna, A; Wabwire-Mangen, F; Yeka, A | 1 |
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| Benga-De, E; Doumbo, O; Faye, O; Gaye, O; Kayentao, K; Lo, Y; Moran, AC; Moreira, PM; Newman, RD; Parise, ME; Steketee, RW; Yameogo, M | 1 |
| Abdulmumini, U; Gebremeskel, T; Gebremichael, A; Ghebrat, Y; Gunawardena, D; Kosia, A; Mebrahtu, G; Mufunda, J; Nyarango, PM; Ogbamariam, A; Okbaldet, Y | 1 |
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| Anokbonggo, WW; Gustafsson, LL; Hellgren, U; Lundblad, MS; Mahindi, M; Ntale, M; Obua, C; Ogwal-Okeng, JW | 1 |
| Balkan, S; Checchi, F; Cousens, S; Guthmann, JP; Legros, D; Olliaro, P; Pinoges, L; van Herp, M | 1 |
| Chavchich, M; Chen, N; Cheng, Q; Fowler, EV; Gatton, ML; Kyle, DE; Peters, JM | 1 |
| Björkman, A; Hugosson, E; Montgomery, SM; Premji, Z; Troye-Blomberg, M | 1 |
| Abodo, RT; Basco, LK; Ndounga, M; Ngane, VF; Same-Ekobo, A; Soula, G; Youmba, JC | 1 |
| D'Alessandro, U; Erhart, A; Guiguemdé, TR; Ouédraogo, JB; Sanou, B; Tinto, H | 1 |
| Kumar, N; Mlambo, G | 1 |
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| Akther, S; Attlmayr, B; Fukuda, M; Haque, R; Miller, RS; Noedl, H; Salam, MA; Schaecher, K; Thriemer, K; Wagatsuma, Y | 1 |
| Browne, E; Bruce, J; Chandramohan, D; Greenwood, B; Randal, A; Tagbor, H | 1 |
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| Bell, DJ; Molyneux, ME; Nyirongo, SK; Ward, SA; Winstanley, PA | 1 |
| Baird, JK; Bangs, MJ; Chand, K; Elyazar, I; Estiana, L; Lederman, ER; Maguire, JD; Sismadi, P; Sumawinata, IW | 1 |
| Goodman, C; Hetzel, MW; Kachur, SP; Lengeler, C; Makemba, A; Msechu, JJ; Mshinda, H; Nathan, R; Obrist, B; Schulze, A | 1 |
| Aguttu, C; Anokbonggo, WW; Chiria, J; Gustafsson, LL; Hellgren, U; Obua, C; Ogwal-Okeng, JW | 1 |
| Carnevale, EP; DaRe, JT; Kouri, D; McNamara, DT; Mueller, I; Zimmerman, PA | 1 |
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| Legorreta-Herrera, M; Machuca-Rodríguez, C; Moreno-Altamirano, MM; Narváez, V; Ramos-Avila, A; Ventura-Gallegos, JL; Zentella-Dehesa, A | 1 |
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| Cousens, SN; Diallo, DA; Greenwood, BM; Ilboudo-Sanogo, E; Konaté, AT; Nebié, I; Ord, R; Pota, H; Roper, C; Sutherland, C | 1 |
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| D'Alessandro, U; Guiguemdé, TR; Ouédraogo, JB; Tinto, H; van Marck, E; van Overmeir, C; Zongo, I | 1 |
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| Andrianina, NN; Jahevitra, M; Ménard, D; Ramiandrasoa, Z; Randriamanantena, A; Rasoarilalao, N; Ratsimbasoa, A; Raveloson, A; Tuseo, L | 1 |
| Hasan, MA; Klinkenberg, E; Leslie, T; Mayan, MI; Rowland, M; Safi, MH; Whitty, CJ | 1 |
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| Aubouy, A; Bertin, G; Deloron, P; Fievet, N; Kinde-Gazard, D; Kiniffo, R; Kossou, H; Massougbodji, A; Sagbo, JC | 1 |
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| Durrani, N; Kolaczinski, K; Rahim, S; Rowland, M | 1 |
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| Alam, MT; Das, MK; Dash, AP; Dev, V; Sharma, YD; Singh, N; Upadhyay, M; Vinayak, S | 1 |
| Nsungwa-Sabiiti, J; Ogwal-Okeng, J; Pariyo, G; Peterson, S; Petzold, MG; Tomson, G | 1 |
| Browne, E; Bruce, J; Chandramohan, D; Greenwood, B; Ord, R; Randall, A; Tagbor, H | 1 |
| Batty, KT; Davis, TM; Ilett, KF; Karunajeewa, HA; Lammey, J; Law, I; Lin, E; Mueller, I; Page-Sharp, M; Siba, P | 1 |
| Beck, HP; Genton, B; Goroti, M; Maku, P; Marfurt, J; Müeller, I; Reeder, JC; Sie, A | 1 |
| Afsharpad, M; Djadid, ND; Raeisi, A; Zakeri, S | 1 |
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| Bissagnene, E; Die-Kakou, H; Jansen, FH; Lesaffre, E; Penali, LK; Zattera, MJ | 1 |
| Ahmed, BS; Andriantsoanirina, V; Jahevitra, M; Ménard, D; Rabarijaona, LP; Randrianarivo-Solofoniaina, AE; Rasolofomanana, JR | 1 |
| Dabo, CA; Diallo, M; Diarra, MA; Doumbo, O; Kayentao, K; Ongoiba, A; Sangho, H; Saye, R; Yattara, O | 1 |
| Akida, JA; Lemnge, MM; Lugimbana, L; Malebo, HM; Malle, LN; Segeja, MD | 1 |
| Bougouma, EC; Diarra, A; Konaté, AT; Nébié, I; Ouédraogo, A; Sirima, SB; Tiono, AB | 2 |
| Abiona, TC; Asa, OO; Fatusi, AO; Ijadunola, KT; Onayade, AA | 1 |
| Stepniewska, K; White, NJ | 1 |
| Kolawole, SO; Ogungbamigbe, TO; Ogunro, PS; Ojurongbe, O; Okanlawon, BM | 1 |
| Adamou, S; Adehossi, E; Duchemin, JB; Hassane, H; Ibrahim, ML; Jeanne, I; Konate, L; Ousmane, I | 1 |
| Kar, SK; Kerketta, AS; Mohapatra, SS | 1 |
| Arai, C; Brun, R; Ge, JF; Ihara, M; Kaiser, M; Wittlin, S | 1 |
| Diarra, M; Guissou, IP; Ouédraogo, LT; Somé, IT | 1 |
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| Almeras, L; Assi, S; Ba, F; Baragatti, M; Basco, L; Bogreau, H; Briolant, S; Desbordes, M; Eggelte, T; Foumane, V; Fusai, T; Gardella, F; Henry, MC; Kientega, PT; Lalou, R; Martelloni, M; Pradines, B; Rogier, C; Simon, F; Trape, JF | 1 |
| Cortés, LJ; Guerra, AP; Knudson, A; Nicholls, RS; Pérez, MA; Usta, C | 1 |
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| Adam, I; Elmardi, KA; Malik, EM | 1 |
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| Brabin, BJ; Coulibaly, SO; D'Alessandro, U; Gies, S; Ky, C; Ouattara, FT | 1 |
| Endo, T; Iwagami, M; Kamei, K; Kano, S; Kawazu, S; Komaki-Yasuda, K; Ohmae, H; Saito-Nakano, Y; Tanabe, K | 1 |
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| Benchimol, C; Bernardino, L; do Rosário, VE; Figueiredo, P; Lopes, D; Nogueira, F; Varandas, L | 1 |
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| Biggs, BA; Caruana, SR; Cowman, AF; Phuc, BQ; Thanh, NV; Thuan, le K; Tien, NT | 1 |
| Davis, TM; Gomorrai, PS; Griffin, S; Ilett, KF; Karunajeewa, HA; Kotab, K; Lautu, D; Law, I; Lin, E; Mueller, I; Oa, O; Page-Sharp, M; Salman, S; Senn, M; Siba, P; Suano, P; Tarongka, N; Ura, A; Wong, R | 1 |
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| Dankyau, M; Madaki, AJ; Ogunfowokan, O; Thacher, TD | 1 |
| Björkman, A; Fidock, DA; Gil, JP; Mårtensson, A; Petersen, I; Premji, Z; Sisowath, C; Veiga, MI | 1 |
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| Anvikar, A; Bhatt, RM; Dua, VK; Kar, PK | 1 |
| Diarra, A; Gansané, A; Konaté, AT; Nébié, I; Ouédraogo, A; Sirima, BS; Soulama, I; Tiono, A | 1 |
| A-Elbasit, IE; Agboghoroma, CO; Bâ, el-H; Barnes, KI; Bonnet, M; Chanda, P; Chandramohan, D; Cissé, B; Clarke, S; Dejene, S; Diallo, DA; Dunyo, S; Elegba, OY; Evehe, MS; Getachew, A; Giha, HA; Grobusch, MP; Guthmann, JP; Hawela, M; Inojosa, W; Kachur, SP; Katokele, ST; Kweku, M; Lynch, C; Malisa, AL; Matondo, A; Mbacham, W; Mombo-Ngoma, G; Naidoo, I; Njie, F; Ord, R; Owusu-Agyei, S; Pearce, RJ; Pota, H; Roper, C; Rwakimari, JB; Sharp, B; Streat, E; Swarthout, TD; Uusiku, P; van den Broek, IV | 1 |
| Afrane, Y; Amenya, DA; Baliraine, FN; Bonizzoni, M; Githeko, AK; Yan, G | 1 |
| bin Reza, F; Chiodini, PL; Doherty, JF; Fifer, H; Gothard, P; Haustein, T; Nicholas, M; Njimgye-Tekumafor, NE; Pearce, RJ; Polley, SD; Sutherland, CJ | 1 |
| Abdirahman, A; Borrmann, S; Kiara, SM; Kokwaro, G; Mackinnon, M; Marsh, K; Mwai, L; Nzila, A; Ochong, E; Sasi, P; Ward, S | 1 |
| Daniel-Ribeiro, CT; de Oliveira, NK; de Souza, JM; Ferreira-da-Cruz, Mde F; Gama, BE; Santos, F; Zalis, MG | 1 |
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| Andrianaranjaka, V; Andriantsoanirina, V; Bouchier, C; Durand, R; Jahevitra, M; Ménard, D; Mercereau-Puijalon, O; Rabarijaona, LP; Rabearimanana, S; Radrianjafy, R; Randriantsoa, T; Rason, MA; Ratsimbasoa, A; Tichit, M | 1 |
| Asih, PB; Coutrier, FN; Dewi, RM; Kusumaningtyas, MA; Rahmat, A; Rogers, WO; Rozi, IE; Sauerwein, RW; Susanti, AI; Sutamihardja, A; Syafruddin, D; van der Ven, AJ | 1 |
| Nakiboneka, D; Nakibuuka, V; Ndeezi, G; Ndugwa, CM; Tumwine, JK | 1 |
| Baiwog, F; Davis, TM; Gomorai, S; Griffin, S; Ilett, KF; Kandai, J; Karunajeewa, HA; Kose, K; Mueller, I; O'Halloran, SJ; Rogerson, SJ; Salman, S; Siba, P; Winmai, J | 1 |
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| Baisor, M; Beck, HP; Genton, B; Hastings, IM; Marfurt, J; Müller, I; Oa, O; Reeder, JC; Sie, A; Smith, TA | 1 |
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| Bangs, MJ; Basri, H; Chand, K; Elyazar, I; Kinzer, MH; Lederman, ER; Maguire, JD; Rogers, WO; Susanti, AI; Taleo, G | 1 |
| Ali, E; Babiker, HA; Reece, SE; Schneider, P | 1 |
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| Adelsberger, JW; Baseler, MW; Imamichi, T; Oguariri, RM | 1 |
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| Ballif, M; Beck, HP; Crameri, A; Fafale, A; Felger, I; Genton, B; Hii, J; Marfurt, J | 1 |
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| Arora, U; Dash, AP; Dhillon, GP; Meshnick, SR; Shah, NK; Valecha, N | 1 |
| Bichenkova, E; Cabal, GG; Díaz, C; dos Santos, DJ; Douglas, KT; Guedes, RC; Gut, J; Lavrado, J; Moreira, R; Mota, MM; Paulo, A; Prudêncio, M; Rosenthal, PJ | 1 |
| Beg, MA; Ghanchi, NK; Jafri, S; Mårtensson, A; Ursing, J; Veiga, MI | 1 |
| Alam, MT; Asamoa, K; Barnwell, JW; de Souza, DK; Duah, NO; Ghansah, A; Griffing, SM; Koram, KA; Poe, AC; Slutsker, L; Udhayakumar, V; Vinayak, S; Wilson, MD | 1 |
| Bouraima, A; Briand, V; Choudat, I; Cot, M; Cottrell, G; Dechavanne, C; Fayomi, B; Garcia, A; Guerra, J; Le Port, A; Massougbodji, A; Migot-Nabias, F | 1 |
| Terlouw, DJ; van Eijk, AM | 1 |
| Adhikari, M; Alifrangis, M; Bygbjerg, IC; Kapel, CM; Ranjitkar, S; Schousboe, ML; Thomsen, TT | 1 |
| Bera, DK; Biswas, A; Das, M; Das, S; Guha, SK; Kundu, PK; Maji, AK; Mullick, S; Ray, K; Roy, D; Saha, P; Sengupta, S | 1 |
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| Adeel, AA; Chance, ML; Hassan, AA; Mubjer, RA | 1 |
| Casimiro, P; Culleton, R; Hayashida, N; Inoue, M; Isozumi, R; Kaneko, O; Nakazawa, S; Ndounga, M; Sunahara, T; Tanabe, K; Tsumori, Y; Uemura, H | 1 |
| Egwang, TG; Kiyingi, HS; Nannyonga, M | 1 |
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| Afsharpad, M; Djadid, ND; Pirahmadi, S; Zakeri, S | 1 |
| Blackstock, AJ; Garner, K; Gatei, W; Gimnig, JE; Hamel, MJ; Hawley, WA; Kariuki, S; Lindblade, K; Nahlen, B; Phillips-Howard, P; Shah, M; Shi, YP; Slutsker, L; ter Kuile, F; Terlouw, D; Vanden Eng, J; Walker, E | 1 |
| Mita, T; Saito-Nakano, Y; Tanabe, K | 1 |
| Ali, I; Barends, M; Beshir, K; Durrani, N; Hallett, R; Kolaczinski, K; Lee, S; Leslie, T; Ord, R; Rowland, M | 1 |
| Barnwell, JW; Collins, WE; Galland, GG; Jeffery, GM; Nace, D; Sullivan, JS; Williams, A; Williams, T | 1 |
| Diarra, A; Dodoo, D; Konate, A; Nebie, I; Ouedraogo, A; Sirima, SB; Soulama, I; Theisen, M; Tiono, A; Traore, A | 1 |
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| Al-Farsi, HM; Al-Hashami, ZS; Al-Qahtani, A; Al-Sheikh, AA; Babiker, HA; Bin Dajem, SM | 1 |
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| Garner, P; Gelband, H; Graves, PM | 3 |
| Aldana, I; Bertani, S; Deharo, E; Garavito, G; Quiliano, M; Valentin, A | 1 |
| Mita, T; Tanabe, K | 1 |
| Anvikar, AR; Arora, U; Bhatt, RM; Das, MK; Dhariwal, AC; Ghosh, SK; Gupta, R; Kaitholia, K; Kumar, A; Mishra, N; Shah, NK; Sharma, SK; Singh, JP; Sonal, GS; Srivastava, B; Valecha, N | 1 |
| Das Sutar, SK; Dhangadamajhi, G; Kar, SK; Ranjit, M | 1 |
| Azagnandji, C; Bello, M; Chippaux, JP; d'Almeida, S; Kinde Gazard, D; Koussihoude, L; Massougbodji, A; Ndam, NT; Ogouyèmi-Hounto, A; Ollo, E | 1 |
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| Altman, S; Augagneur, Y; Ben Mamoun, C; Cornillot, E; Garg, A; Ghosal, A; Jaubert, L; Kumar, P; Pachikara, N; Said, HM; Schiavoni, M; Usmani-Brown, S; Wesolowski, D; Zeller, S | 1 |
| Apers, S; Cimanga, RK; Cos, P; Kambu, OK; Kikueta, CM; Maes, L; Mavinga, ST; Mbamu, BM; Mbenza, AP; Pieters, L | 1 |
| Dara, A; Djimdé, A; Doumbo, OK; Doumbo, S; Doumtabé, D; Kayentao, K; Ongoiba, OA; Ouologuem, TD; Traoré, B | 1 |
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| Azagnandji, C; Bello, M; Chippaux, JP; Fadégnon, G; Kinde Gazard, D; Massougbodji, A; Moussiliou, A; Ndam, NT; Ogouyèmi-Hounto, A | 1 |
| Anvikar, AR; Das, MK; Gupta, R; Mishra, N; Rana, R; Shahi, B; Singh, S; Valecha, N | 1 |
| Macedo De Oliveira, A; Rodriguez, B; Soto, AM; Sridaran, S; Udhayakumar, V | 1 |
| Arinaitwe, E; Baliraine, FN; Conrad, MD; Dorsey, G; Greenhouse, B; Kamya, M; Mbogo, GW; Nankoberanyi, S; Nsobya, SL; Rosenthal, PJ; Staedke, SG; Tappero, J; Tukwasibwe, S | 1 |
| Arróspide, N; Cabezas-Sánchez, C; de Mora, D; Diaz-Cortéz, CE; Gutierrez, S; Hijar-Guerra, G; Veloz-Perez, R | 1 |
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| Ahmed, MA; Bhattacharyya, DR; Bora, K; Goswami, BK; Mahanta, J; Mohapatra, PK; Prakash, A; Sarma, B; Sarma, DK | 1 |
| Adewunmi, AA; Akinlusi, FM; Akinola, OI; Davies, NO; Nzeribe-Abangwu, UO; Ogundele, SO; Rabiu, KA | 1 |
| Bardaji, A; Betuela, I; Hanieh, S; Kongs, C; Lufele, E; Menendez, C; Mueller, I; Ome-Kaius, M; Robinson, LJ; Rogerson, SJ; Rosanas-Urgell, A; Samol, P; Schofield, L; Siba, P; Singirok, D; Suen, CS; Sui, D; Umbers, AJ; Unger, HW; Wangnapi, RA; Wapling, J | 1 |
| Dondorp, A; von Seidlein, L | 1 |
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| Girmann, M; Hahn, A; Maïga-Ascofaré, O; May, J; Poppert, S; Rakotozandrindrainy, R; Randriamampionona, N; Schwarz, NG | 1 |
| Brown, GV; Hasang, W; Mueller, I; Randall, LM; Rogerson, SJ; Siba, PM; Teo, A; Unger, HW | 1 |
| Combrinck, JM; Egan, TJ; Fong, KY; Gibhard, L; Smith, PJ; Wright, DW | 1 |
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| Ayoub, A; Duparc, S; Kamiza, S; Kimani, J; Orrico, R; Phiri, K; Robbins, J; Rojo, R; Vandenbroucke, P | 1 |
| Abdul-Ghani, R; Alareqi, LMQ; Fong, MY; Lau, YL; Mahdy, MAK; Mahmud, R | 1 |
| Barnwell, JW; Boncy, J; Chang, MA; Griffing, S; Huber, C; Ljolje, D; Lucchi, N; McMorrow, M; Morton, LC; Okoth, SA; Oscar, R; Townes, D; Udhayakumar, V | 1 |
| Grobusch, MP; Hakizimana, E; Kateera, F; Kumar, N; Mens, PF; Mutesa, L; Nsobya, SL; Tukwasibwe, S; van Vugt, M | 1 |
| Abdullah, NR; Imwong, M; Jelip, J; Mohd Abd Razak, MR; Mudin, RN; Muhammad, A; Muniandy, PK; Norahmad, NA; Rundi, C; Saat, MN; Sastu, UR; Syed Mohamed, AF; Tikuson, M; Yusof, N | 1 |
| Arez, AP; Berzosa, P; de Sousa, B; Guerra, M; Mendes, C; Ndong-Mabale, N; Neres, R; Salgueiro, P | 1 |
| Liu, XJ; Peng, HJ; Wei, HX; Xia, J; Zhou, LJ | 1 |
| Banura, P; Guler, JL; Houpt, E; Huang, F; Jacob, ST; Laufer, MK; Liu, J; Moore, CC; Pholwat, S; Stroup, S | 1 |
| Björkman, A; Jovel, IT; Mårtensson, A; Roper, C; Ursing, J | 1 |
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| Chesnokova, O; Oleinikov, AV; Oleinikov, IV; Tcherniuk, SO | 1 |
| Amambua-Ngwa, A; Awolola, TS; Idowu, ET; Olukosi, YA; Oyebola, KM | 1 |
| Baiwog, F; Davis, TME; Ilett, KF; Karunajeewa, HA; Kose, K; Mueller, I; Page-Sharp, M; Rogerson, SJ; Salman, S; Siba, PM | 1 |
| Bhagavathula, AS; Gebreyohannes, EA; Seid, MA; Tegegn, HG | 1 |
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| Boudová, S; Divala, T; Laufer, MK; Mawindo, P; Mungwira, R; Tomoka, T | 1 |
| Choi, L; Garner, P; Gelband, H; Graves, PM | 1 |
| Anvikar, A; Goomber, S; Mishra, N; Valecha, N; Yadav, CP | 1 |
| Bazmani, A; Hazratian, T; Khorashad, AS; Mahami-Oskouei, M; Parsaei, M; Raeisi, A; Sarafraz, S; Shahbazi, A; Spotin, A; Zaman, J | 1 |
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| Cumming, BM; Goldring, JPD | 1 |
| Baker, DA; Benavente, ED; Campino, S; Clark, TG; Ravenhall, M; Sutherland, CJ | 1 |
| Abdel-Muhsin, AA; Abdelraheem, MH; Al Dhuhli, A; Al Hosni, A; Al Rubkhi, M; Al-Hamidhi, S; Babiker, HA; Bakhiet, AMA; Gadalla, A; Gismelseed, L; Kheir, A; Mukhtar, M; Naiem, A; Omer, S; Sultan, AA | 1 |
| Aydemir, O; Bailey, JA; Bhatt, S; Brazeau, NF; Carrel, M; Deutsch-Feldman, M; Juliano, JJ; Kashamuka, M; Meshnick, SR; Taylor, SM; Tshefu, AK; Verity, R | 1 |
| Song, TQ; Tian, BP; Wang, CC | 1 |
| Abuaku, B; Anto, F; Aydemir, O; Bailey, J; Ghansah, A; Hathaway, NJ; Marsh, PW; Mensah, BA; Myers-Hansen, JL; Opoku, M | 1 |
| Combrinck, JM; de Sousa, ACC; Egan, TJ; Maepa, K | 1 |
| Boncy, J; Chang, MA; Druetz, T; Eisele, TP; Elismé, T; Existe, A; Hamre, KES; Herman, C; Huber, CS; Lemoine, JF; Mace, KE; Mondélus, G; Pierre, B; Présumé, J; Rogier, E; Romilus, I; Udhayakumar, V | 1 |
| Aydemir, O; Bailey, JA; Brazeau, NF; Conrad, M; Denton, M; Fulton, T; Ghani, AC; Ghansah, A; Gutman, J; Hathaway, NJ; Ishengoma, DS; Juliano, JJ; Marsh, PW; Mensah, BA; Meshnick, SR; Morgan, AP; Moss, WJ; Mulenga, M; Mwandagalirwa, MK; Myers-Hansen, JL; Ngondi, J; Norris, DE; Parr, JB; Rosenthal, PJ; Thwai, K; Tshefu, AK; Tumwebaze, PK; Verity, R; Watson, OJ | 1 |
| Abdel Hamid, MM; Abdelraheem, MH; Elaagip, AH; Elamin, EA; Hassan, AO; Hussien, M; Mohamed, AO; Salama, AHA | 1 |
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Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Boncy, J; Chang, MA; Hamre, KES; Lemoine, JF; Mace, K; Namuyinga, R; Pierre, B; Rogier, EW; Udhayakumar, V | 1 |
| Abuaku, B; Ahorlu, C; Awandare, G; Ghansah, A; Koram, KA; Mensah, BA; Myers-Hansen, JL; Ngwa, AA; Oyebola, MK; Wilson, MD | 1 |
| Al Khaja, KAJ; Sequeira, RP | 1 |
| Mirza, AZ; Sayqal, A; Shamshad, H; Zeb, J | 1 |
| Achidi, EA; Bila, RB; Feugaing Sofeu, DD; Ivo, EP; Taiwe, GS; Tatsinkou Fossi, B; Toukam, LL | 1 |
| Libre, C; Oleinikov, A; Rahman, F; Tcherniuk, S | 1 |
| Joya, CA; Lizewski, SE; Valdivia, HO; Villena, FE | 1 |
| Chirwa, T; Divala, T; Kazembe, L; Laufer, MK; Mathanga, D; Mukaka, M; Patson, N; Peterson, I | 1 |
| Akinyi, M; Bejon, P; de Laurent, Z; Gichuki, P; Kandie, R; Kepha, S; Kimenyi, KM; Mwandawiro, C; Ndwiga, L; Ochola-Oyier, LI; Okoyo, C; Osoti, V; Snow, RW; Wamae, K | 1 |
| Kalawong, L; Khumchum, N; Kuesap, J; Suphakhonchuwong, N | 1 |
| Chenet, SM; Cortés, LJ; Guerra, AP; Lucchi, NW; Macedo de Oliveira, A; Olivera, MJ | 1 |
| Abuaku, B; Afrane, Y; Amoah, LE; Cui, L; Duah-Quashie, NO; Duan, M; Huang, Y; Li, X; Pan, M; Qin, Y; Sun, K; Wang, X; Yang, Q; Yang, Z; Zeng, W; Zhao, H; Zhao, W; Zhou, L; Zhu, W | 1 |
| Bal, M; Das, A; Khan, N; Pati, S; Rana, R; Ranjit, M; Sandeepta, S | 1 |
| Koonyosying, P; Srichairatanakool, S; Sthitmatee, N; Tiwananthagorn, S | 1 |
80 review(s) available for pyrimethamine and chloroquine
| Article | Year |
|---|---|
Recent advances in malaria drug discovery.
Topics: Animals; Antimalarials; Drug Discovery; Humans; Liver; Liver Transplantation; Malaria; Molecular Structure | 2013 |
Approaches to protozoan drug discovery: phenotypic screening.
Topics: Drug Discovery; Humans; Molecular Structure; Neglected Diseases; Phenotype; Plasmodium falciparum; Protozoan Infections; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular Structure; Paclitaxel; Quinolines | 2020 |
[Present condition and problems of malaria].
Topics: Chloroquine; Drug Combinations; Drug Synergism; Humans; Malaria; Pyrimethamine; Sulfanilamides | 1978 |
[Current information on treatment and prophylaxis of malaria (author's transl)].
Topics: Adolescent; Adult; Amodiaquine; Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Female; Humans; Infant; Insect Repellents; Malaria; Male; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pregnancy; Pyrimethamine; Quinine; Sulfadiazine; Sulfadoxine; Tetracycline | 1979 |
[Contribution of molecular genetics to the understanding of chemoresistance of Plasmodium falciparum].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Drug Resistance; Folic Acid Antagonists; Membrane Glycoproteins; Molecular Biology; Mutation; Plasmodium falciparum; Pyrimethamine; Triazines | 1992 |
[The detection and characterization of drug resistant malaria parasites using genetic markers].
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Gene Amplification; Genetic Markers; Mutation; Plasmodium malariae; Pyrimethamine; Tetrahydrofolate Dehydrogenase | 1992 |
Development of the new antimalarial drug pyronaridine: a review.
Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine | 1992 |
Extension of multiple drug resistant Plasmodium falciparum malaria in Africa: report of a Central African case.
Topics: Adult; Animals; Chloroquine; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides | 1989 |
The chemoprophylaxis of malaria.
Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine | 1987 |
Chemoprophylaxis of malaria.
Topics: Adolescent; Adult; Africa; Anemia, Hemolytic; Asia; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Female; Humans; Infant; Kinetics; Malaria; Pacific Islands; Pregnancy; Primaquine; Pyrimethamine; Sulfadoxine; Travel | 1986 |
Use of pyrimethamine-sulfadoxine (Fansidar) in prophylaxis against chloroquine-resistant Plasmodium falciparum and Pneumocystis carinii.
Topics: Acquired Immunodeficiency Syndrome; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pneumonia, Pneumocystis; Pyrimethamine; Sulfadoxine; Sulfanilamides; Travel | 1987 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Biochemical aspects of drug action and resistance in malaria parasites.
Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Synergism; Folic Acid; Folic Acid Antagonists; Hemin; Plasmodium; Pyrimethamine; Sulfanilamides | 1985 |
Pharmacokinetics of antimalarial drugs: their therapeutic and toxicological implications.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Half-Life; Humans; Kinetics; Male; Mefloquine; Mice; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine; Sulfalene | 1985 |
Recent advances in antimalarial chemotherapy and drug resistance.
Topics: Agglutination; Amodiaquine; Animals; Anti-Bacterial Agents; Antimalarials; Chloroquine; Cross Reactions; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Haplorhini; Humans; Lincomycin; Malaria; Pigments, Biological; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines; Structure-Activity Relationship; Sulfonamides; Sulfones | 1974 |
The present status of chloroquine in the drug treatment of malaria.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Sulfones; Triazines | 1972 |
Development of new antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Folic Acid Antagonists; Humans; Malaria; Methanol; Phenanthrenes; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinolines; Research; Sulfadiazine; Sulfonamides; Sulfones; United States | 1972 |
A review of the drug sensitivity of Plasmodium falciparum in Thailand.
Topics: Chloroquine; Drug Resistance; Geography; Humans; Malaria; Methylamines; Naphthacenes; Plasmodium falciparum; Pyrazines; Pyrimethamine; Pyrimidines; Quinine; Sulfamethoxazole; Sulfonamides; Tetracycline; Thailand; Trimethoprim | 1972 |
[Importation of malaria into the Federal Republic of Germany including Berlin (West) in the last ten years (1963-1972)].
Topics: Africa; Age Factors; Aircraft; Amodiaquine; Antimalarials; Asia; Berlin; Chloroquine; Disease Outbreaks; Epidemiologic Methods; Europe; Female; Germany, West; Humans; Malaria; Male; Proguanil; Pyrimethamine; Recurrence; Retrospective Studies; Sex Factors; Travel; World Health Organization | 1974 |
The pharmacology of the antimalarials. A rational approach to the therapy of resistant falciparum malaria.
Topics: Amodiaquine; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Sulfadimethoxine; Sulfisoxazole | 1969 |
Drug resistance in malaria--a perspective.
Topics: Adult; Africa; Animals; Antimalarials; Asia, Southeastern; Child; Chloroquine; Drug Resistance, Microbial; Female; Humans; Immunity; Insect Control; Malaria; Male; Mice; Mutation; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; South America | 1969 |
Chemotherapy of the drug-resistant malarias.
Topics: Chloroquine; Cinchona; Drug Resistance, Microbial; Malaria; Mutation; Phytotherapy; Plants, Medicinal; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Quinolines; Sulfonamides; Sulfones | 1969 |
Malaria. Chemoprophylaxis and chemotherapy.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides; Triazines | 1971 |
The mechanisms of drug resistance in malaria parasites.
Topics: Animals; Antimalarials; Birds; Chickens; Chloroquine; Citric Acid Cycle; Drug Resistance, Microbial; Folic Acid Antagonists; Glycolysis; Haplorhini; Mice; Mitochondria; Models, Biological; Naphthoquinones; Plasmodium; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinolines; Succinate Dehydrogenase; Sulfonamides | 1971 |
Resistance of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Asia; Chloroquine; DNA; Drug Resistance; Drug Synergism; Hemin; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Quinolines; Research; RNA; South America | 1984 |
[Progress in immunodiagnosis and chemotherapy of protozoan infections].
Topics: Amebiasis; Animals; Antibodies; Babesiosis; Chloroquine; Drug Resistance, Microbial; Giardiasis; Humans; Leishmaniasis; Malaria; Mefloquine; Pneumocystis; Pneumonia, Pneumocystis; Primaquine; Protozoan Infections; Pyrimethamine; Quinine; Quinolines; Serologic Tests; Sulfadoxine; Tetracycline; Toxoplasmosis; Trypanosomiasis | 1983 |
Malaria 1984. Part I. Malaria prophylaxis.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Mosquito Control; Plasmodium falciparum; Plasmodium vivax; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; South Africa; Sulfadoxine | 1984 |
Practical therapeutics malaria chemoprophylaxis.
Topics: Adult; Africa, Eastern; Aminoquinolines; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Sulfadoxine | 1984 |
Chemoprophylaxis of malaria in Africa: the spent "magic bullet".
Topics: Africa; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Travel | 1982 |
[Drug resistance in malaria].
Topics: Africa; Amodiaquine; Animals; Asia; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; South America; Sulfanilamides | 1980 |
[Urgent need for new antimalarias (author's transl)].
Topics: Antimalarials; Biological Availability; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Immunotherapy; Mefloquine; Piperidines; Pyrimethamine; Quinolines; Sulfadoxine; World Health Organization | 1981 |
The genetics of drug resistance in malaria parasites.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Malaria; Plasmodium; Pyrimethamine; Rodentia | 1980 |
Drugs for the treatment of parasitic infection.
Topics: Antimony; Bithionol; Chloroquine; Diethylcarbamazine; Humans; Mebendazole; Melarsoprol; Metronidazole; Niclosamide; Niridazole; Oxamniquine; Parasitic Diseases; Pentamidine; Piperazines; Primaquine; Pyrantel Pamoate; Pyrimethamine; Suramin; Thiabendazole; Trichlorfon | 1982 |
The present status of malaria chemotherapy: mefloquine, a novel antimalarial.
Topics: Amodiaquine; Animals; Antimalarials; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dogs; Drug Therapy, Combination; Erythrocytes; Female; Humans; Lethal Dose 50; Macaca mulatta; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Protein Conformation; Pyrimethamine; Quinolines; Rats; Stereoisomerism; Swine | 1981 |
Genetic variation in malaria parasites.
Topics: Animals; Antigens; Chloroquine; Chromosomes; Crosses, Genetic; Drug Resistance, Microbial; Enzymes; Genetic Markers; Genetic Variation; Plasmodium; Plasmodium falciparum; Pyrimethamine; Virulence | 1982 |
Clinical pharmacokinetics in the treatment of tropical diseases. Some applications and limitations.
Topics: Chloroquine; Diethylcarbamazine; Drug Resistance; Echinococcosis; Filariasis; Humans; Malaria; Mefloquine; Pharmacokinetics; Phenanthrenes; Pyrimethamine; Quinine; Sulfadoxine; Tropical Medicine | 1994 |
[Malaria: the most important emergency in subjects returning from the tropics].
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Emergencies; Humans; Malaria; Malaria, Falciparum; Mefloquine; Plasmodium; Pyrimethamine; Quinidine; Quinine; Sulfadoxine | 1993 |
[Malaria and drug resistance].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria; Microbial Sensitivity Tests; Plasmodium; Proguanil; Pyrimethamine | 1996 |
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine as a treatment for uncomplicated malaria--a systematic review.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine | 1998 |
Comparative efficacy and safety of chloroquine and alternative antimalarial drugs: a meta-analysis from six African countries.
Topics: Africa, Eastern; Africa, Western; Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Costs; Humans; Malaria; Mefloquine; Patient Selection; Phenanthrenes; Pyrimethamine; Quinine; Safety; Sulfadoxine; Treatment Outcome | 1999 |
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria.
Topics: Adult; Amodiaquine; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Sulfadoxine | 2000 |
Combination therapy for malaria in Africa: hype or hope?
Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Cross-Cultural Comparison; Half-Life; Humans; Insecticide Resistance; Malaria; Mefloquine; Pyrimethamine; Self Medication; Sesquiterpenes; Sulfadoxine; Thailand | 2000 |
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria.
Topics: Adult; Amodiaquine; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Sulfadoxine | 2001 |
Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?
Topics: Africa South of the Sahara; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2001 |
Malaria: a rising incidence in the United States.
Topics: Antimalarials; Chemoprevention; Chloroquine; Drug Combinations; Drug Resistance; Female; Global Health; Humans; Incidence; Malaria; Malaria, Falciparum; Male; Medical History Taking; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Sulfadoxine; Travel; United States | 2002 |
The mechanisms of resistance to antimalarial drugs in Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Antimetabolites; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 2003 |
Amodiaquine for treating malaria.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine | 2003 |
[EXTRAMALARIAL THERAPUETIC APPLICATIONS OF ANTIMALARIAL DRUGS. 1. CLINICAL UTILIZATIONS].
Topics: Amodiaquine; Antimalarials; Chloroquine; Collagen Diseases; Dermatology; Drug Utilization; Epilepsy; Female; Heart Diseases; Hematology; Humans; Hydroxychloroquine; Hypersensitivity; Multiple Sclerosis; Muscular Diseases; Neurology; Parasitic Diseases; Pharmacology; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Toxicology; Uterus | 1963 |
WHO, the Global Fund, and medical malpractice in malaria treatment.
Topics: Africa; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Costs; Drug Resistance; Drug Therapy, Combination; Humans; International Agencies; Malaria; Malaria, Falciparum; Malpractice; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; World Health Organization | 2004 |
Genetic and biochemical aspects of drug resistance in malaria parasites.
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Resistance; Drug Resistance, Multiple; Humans; Linkage Disequilibrium; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2004 |
[Combined antimalarial therapy using artemisinin].
Topics: Amodiaquine; Animals; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2004 |
Malaria in endemic areas.
Topics: Antimalarials; Artemether; Artemisinins; Blood Transfusion; Chloroquine; Deferoxamine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Effectiveness of antimalarial drugs.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Life Cycle Stages; Malaria; Mefloquine; Patient Compliance; Plasmodium; Primaquine; Pyrimethamine; Quinine; Secondary Prevention; Sulfadoxine; Treatment Failure | 2005 |
Fitness of drug-resistant malaria parasites.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Humans; Malaria; Mutation; Plasmodium chabaudi; Plasmodium falciparum; Pyrimethamine | 2005 |
Malaria: uncomplicated, caused by Plasmodium falciparum.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Proguanil; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2005 |
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria.
Topics: Adult; Amodiaquine; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Pyrimethamine; Sulfadoxine | 2005 |
Chemoprophylaxis and intermittent treatment for preventing malaria in children.
Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Humans; Infant; Malaria; Pyrimethamine; Randomized Controlled Trials as Topic | 2005 |
Comparative efficacy of chloroquine and sulphadoxine--pyrimethamine in pregnant women and children: a meta-analysis.
Topics: Adolescent; Adult; Africa; Antimalarials; Child; Chloroquine; Drug Combinations; Endemic Diseases; Female; Gravidity; Hemoglobins; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2006 |
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for uncomplicated malaria: a systematic review.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Randomized Controlled Trials as Topic; Research Design; Risk Factors; Sulfadoxine; Treatment Failure | 2006 |
Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Bayes Theorem; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Malaria; Mefloquine; Pyrimethamine; Randomized Controlled Trials as Topic; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Design; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Health Care Surveys; Health Knowledge, Attitudes, Practice; Malaria; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Population Density; Pyrimethamine; Sulfadoxine; Travel; Treatment Outcome | 2009 |
Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sudan; Sulfadoxine; Treatment Failure | 2010 |
Following the path of most resistance: dhps K540E dispersal in African Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Point Mutation; Population Surveillance; Prevalence; Pyrimethamine; Sulfadoxine | 2010 |
Antimalarial drug resistance of Plasmodium falciparum in India: changes over time and space.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Geography; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Outcome | 2011 |
Azithromycin for treating uncomplicated malaria.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Atovaquone; Azithromycin; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Proguanil; Pyrimethamine; Randomized Controlled Trials as Topic; Sulfadoxine; Treatment Failure | 2011 |
Pharmacokinetics of antimalarials in pregnancy: a systematic review.
Topics: Anti-Bacterial Agents; Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 2011 |
Primaquine for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2012 |
Evolution of Plasmodium falciparum drug resistance: implications for the development and containment of artemisinin resistance.
Topics: Africa; Antimalarials; Artemisinins; Asia, Southeastern; Biological Evolution; Chloroquine; Drug Combinations; Drug Resistance; Gene Flow; Humans; Plasmodium falciparum; Pyrimethamine; South America; Sulfadoxine | 2012 |
Malaria.
Topics: Africa South of the Sahara; Amodiaquine; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Asia, Southeastern; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Insecticide-Treated Bednets; Insecticides; Malaria; Malaria Vaccines; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Primary Prevention; Pyrimethamine; Quinine; Quinolines; Seasons; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2014 |
Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine | 2015 |
Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Drug Therapy, Combination; History, 20th Century; History, 21st Century; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2015 |
Antimalarial drug resistance in Africa: key lessons for the future.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Forecasting; Humans; Malaria; Pyrimethamine; Sulfadoxine | 2015 |
Risk of drug resistance in Plasmodium falciparum malaria therapy-a systematic review and meta-analysis.
Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Risk; Sulfadoxine | 2017 |
Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-analysis.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Drug Combinations; Ethanolamines; Ethiopia; Fluorenes; Humans; Malaria, Falciparum; Malaria, Vivax; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Failure | 2017 |
Primaquine or other 8-aminoquinolines for reducing Plasmodium falciparum transmission.
Topics: Adult; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Non-Randomized Controlled Trials as Topic; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Randomized Controlled Trials as Topic; Sulfadoxine; Time Factors | 2018 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Drug treatment and prevention of malaria in pregnancy: a critical review of the guidelines.
Topics: Adult; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artesunate; Chloroquine; Drug Combinations; Female; Humans; Malaria; Parasitemia; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Sulfadoxine | 2021 |
185 trial(s) available for pyrimethamine and chloroquine
| Article | Year |
|---|---|
Chloroquine-resistant malaria in Burma.
Topics: Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfamethoxypyridazine; Trimethoprim | 1975 |
Suppression of malaria with monthly administration of combined sulphadoxine and pyrimethamine.
Topics: Adolescent; Adult; Blood; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Synergism; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukocyte Count; Malaria; Male; Placebos; Plasmodium vivax; Pregnancy; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1975 |
Malaria prophylaxis.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Military Medicine; Plasmodium falciparum; Pyrimethamine; South Africa | 1975 |
Fansimef for prophylaxis of malaria: a double-blind randomized placebo controlled trial.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Double-Blind Method; Drug Combinations; Humans; Incidence; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine; Treatment Outcome | 1992 |
Mefloquine-sulphadoxine-pyrimethamine (Fansimef, Roche) in the prophylaxis of Plasmodium falciparum malaria: a double-blind, comparative, placebo-controlled study.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Double-Blind Method; Drug Combinations; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine | 1992 |
Clinical trials of mefloquine with tetracycline.
Topics: Acute Disease; Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Prospective Studies; Pyrimethamine; Sulfadoxine; Tetracycline | 1992 |
Parasitological, clinical and haematological response of children with Plasmodium falciparum to 4-aminoquinolines and to pyrimethamine-sulfadoxine with quinine in western Kenya.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Hospitals; Humans; Infant; Kenya; Malaria, Falciparum; Male; Pyrimethamine; Quinine; Reticulocytes; Seroepidemiologic Studies; Sulfadoxine | 1992 |
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Mefloquine; Nigeria; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
Development of the new antimalarial drug pyronaridine: a review.
Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine | 1992 |
Falciparum malaria fully cleared by amodiaquine, pyrimethamine-sulfadoxine and pyrimethamine-sulfalene in areas of chloroquine resistance in Dodoma, Tanzania.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sulfadoxine; Sulfalene; Tanzania; Time Factors | 1991 |
Comparison of mefloquine, chloroquine plus pyrimethamine-sulfadoxine (Fansidar), and chloroquine as malarial prophylaxis in eastern Thailand.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Animals; Antimalarials; Cambodia; Chloroquine; Confidence Intervals; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Middle Aged; Pyrimethamine; Sulfadoxine; Survival Analysis; Thailand | 1991 |
Comparison of chloroquine, pyrimethamine and sulfadoxine, and chlorproguanil and dapsone as treatment for falciparum malaria in pregnant and non-pregnant women, Kakamega District, Kenya.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Prospective Studies; Pyrimethamine; Sulfadoxine | 1990 |
[Comparative study of sulfadoxine-pyrimethamine and amodiaquine + sulfadoxine-pyrimethamine for the treatment of malaria caused by chloroquine-resistant Plasmodium falciparum in Maputo, Mozambique].
Topics: Adult; Amodiaquine; Animals; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Hemoglobins; Humans; Leukocyte Count; Malaria; Mozambique; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1990 |
Lack of efficacy of pyrimethamine prophylaxis in pregnant Nigerian women.
Topics: Adolescent; Adult; Animals; Chloroquine; Drug Evaluation; Drug Resistance; Female; Follow-Up Studies; Gestational Age; Humans; Malaria; Nigeria; Parity; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Randomized Controlled Trials as Topic; Tablets | 1989 |
Comparison of the susceptibility of falciparum malaria to mefloquine-sulphadoxine-pyrimethamine and chloroquine in Nigeria.
Topics: Animals; Antimalarials; Child; Chloroquine; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Male; Mefloquine; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides | 1988 |
Trials of mefloquine in vivax and of mefloquine plus 'fansidar' in falciparum malaria.
Topics: Adolescent; Adult; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides | 1985 |
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combinations; Gambia; Humans; Infant; Malaria; Pyrimethamine | 1988 |
Tolerability of long-term malaria prophylaxis with the combination mefloquine + sulfadoxine + pyrimethamine (Fansimef): results of a double blind field trial versus chloroquine in Nigeria.
Topics: Adolescent; Adult; Animals; Antimalarials; Aspartate Aminotransferases; Blood Cell Count; Child; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; gamma-Glutamyltransferase; Humans; Malaria; Male; Mefloquine; Middle Aged; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides | 1988 |
Effectiveness of amodiaquine, sulfadoxine-pyrimethamine, and combinations of these drugs for treating chloroquine-resistant falciparum malaria in Hainan Island, China.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1988 |
Sensitivity of Plasmodium falciparum to mefloquine-sulphadoxine-pyrimethamine (Fansimef) in vivo and to mefloquine alone in vitro in Nigeria.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Evaluation; Drug Resistance; Female; Humans; Malaria; Male; Mefloquine; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinolines; Random Allocation; Sulfadoxine; Sulfanilamides | 1988 |
[Efficacy of amodiaquine, Fansidar and their combination in the treatment of chloroquine-resistant falciparum malaria].
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Double-Blind Method; Drug Combinations; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Random Allocation; Sulfadoxine; Sulfanilamides | 1988 |
[In vivo resistance of Plasmodium falciparum to 4-aminoquinolines and to a sulfadoxine-pyrimethamine combination. II. Study of Manaus, Amazonas 1983-1984].
Topics: Adolescent; Adult; Amodiaquine; Animals; Brazil; Chloroquine; Clinical Trials as Topic; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Random Allocation; Sulfadoxine; Sulfanilamides | 1986 |
Malaria chemoprophylaxis in travellers to east Africa: a comparative prospective study of chloroquine plus proguanil with chloroquine plus sulfadoxine-pyrimethamine.
Topics: Adult; Animals; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Proguanil; Prospective Studies; Pyrimethamine; Random Allocation; Sulfadoxine; Sulfanilamides; Travel | 1988 |
Parasitologic and clinical efficacy of 25 and 50 mg/kg of chloroquine for treatment of Plasmodium falciparum malaria in Rwandan children.
Topics: Animals; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Rwanda | 1988 |
Amodiaquine and sulfadoxine-pyrimethamine as treatment for chloroquine-resistant Plasmodium falciparum in Rwanda.
Topics: Amodiaquine; Animals; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Rwanda; Sulfadoxine; Sulfanilamides | 1988 |
Evaluation of four therapeutic regimens for falciparum malaria in Mozambique, 1986.
Topics: Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mozambique; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1988 |
Double-blind study to assess the efficacy of chlorproguanil given alone or in combination with chloroquine for malaria chemoprophylaxis in an area with Plasmodium falciparum resistance to chloroquine, pyrimethamine and cycloguanil.
Topics: Adolescent; Animals; Antimalarials; Child; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 1987 |
Effects of antimalarial agents on plasma levels of chlorpromazine and its metabolites in schizophrenic patients.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chloroquine; Chlorpromazine; Drug Combinations; Drug Synergism; Female; Humans; Male; Middle Aged; Pyrimethamine; Random Allocation; Schizophrenia; Sulfadoxine | 1988 |
Effects of chloroquine, amodiaquine and pyrimethamine-sulfadoxine on Plasmodium falciparum gametocytemia.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Time Factors | 1986 |
Monthly antimalarial chemotherapy to children in a holoendemic area of Liberia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Hematocrit; Humans; Immunoglobulin G; Liberia; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Spleen; Time Factors | 1986 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; India; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1985 |
Suppressive and curative trials in Plasmodium malariae infection with Fansidar.
Topics: Child; Chloroquine; Clinical Trials as Topic; Drug Combinations; Humans; Malaria; Nephrosis; Plasmodium malariae; Pyrimethamine; Sulfonamides | 1972 |
Sulfalene with pyrimethamine and chloroquine with pyrimethamine in single-dose treatment of Plasmodium falciparum infections. A trial in a rural population in northern Nigeria.
Topics: Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Humans; Infant; Malaria; Nigeria; Plasmodium falciparum; Pyrazines; Pyrimethamine; Rural Health; Sulfanilamides | 1973 |
Combinations of 4-aminobenzoic acid competitors and dihydrofolate dehydrogenase inhibitors in the chemotherapy of malaria. A commentary.
Topics: Africa; Antimalarials; Asia; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Evaluation; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Malaria; Pyrimethamine; Trimethoprim | 1974 |
[New trends in malaria therapy with folic acid antagonists].
Topics: Chloroquine; Clinical Trials as Topic; Folic Acid Antagonists; Humans; Malaria; Nigeria; Pyrimethamine; Sulfonamides | 1968 |
The drug response of a normal and a multi-resistant strain of P. falciparum to sulphalene.
Topics: Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Drug Synergism; Folic Acid Antagonists; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides | 1968 |
Supplemental folates in the therapy of Plasmodium falciparum malaria.
Topics: Administration, Oral; Anemia; Antimalarials; Blood Platelets; Chloroquine; Clinical Trials as Topic; Folic Acid; Hematocrit; Humans; Leucovorin; Leukocyte Count; Leukopenia; Malaria; Male; Military Medicine; Placebos; Plasmodium falciparum; Pyrimethamine; Sulfisoxazole; Vietnam | 1970 |
Prophylactic and sporontocidal treatment of chloroquine resistant Plasmodium falciparum from Malaya.
Topics: Adult; Amodiaquine; Anopheles; Antimalarials; Blood; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Malaysia; Male; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine | 1970 |
Characterization of a drug resistant strain of Plasmodium falciparum from the Philippines.
Topics: Adult; Anopheles; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Malaria; Male; Philippines; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine | 1971 |
Prophylactic and sporontocidal treatment of chloroquine-resistant Plasmodium falciparum from Vietnam.
Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Methemoglobin; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfonamides; United States; Vietnam | 1971 |
Treatment of Plasmodium falciparum malaria in Cameroon with a single dose of antifolic drugs. 1. Combination of sulfametopyrazine and pyrimethamine.
Topics: Adolescent; Adult; Aged; Cameroon; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Synergism; Female; Humans; Infant; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfonamides; Time Factors | 1971 |
Clinical studies with a drug-resistant strain of Plasmodium falciparum from Vietnam.
Topics: Adult; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Vietnam | 1966 |
Characteristics of four new drug-resistant strains of Plasmodium falciparum from South-East Asia.
Topics: Adult; Antimalarials; Asia, Southeastern; Chloroquine; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine | 1969 |
Effectiveness of amodiaquine as treatment for chloroquine-resistant Plasmodium falciparum infections in Kenya.
Topics: Adolescent; Amodiaquine; Blood; Child; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Female; Follow-Up Studies; Humans; Kenya; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Recurrence; Sulfadoxine | 1984 |
Tolerability of long-term prophylaxis with fansidar: a randomized double-blind study in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Blood Cell Count; Chloroquine; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Liver; Malaria; Male; Middle Aged; Nigeria; Pyrimethamine; Sulfadoxine; Sulfanilamides; Time Factors; Vision Disorders | 1984 |
The in vivo sensitivity of Plasmodium falciparum to chloroquine and to sulphadoxine-pyrimethamine combination in Ibadan, Nigeria.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Infant; Malaria; Nigeria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1981 |
Sulfadoxine-pyrimethamine for the treatment of acute malaria in children in Papua New Guinea. I. Plasmodium falciparum.
Topics: Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; New Guinea; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1982 |
Sulfadoxine-pyrimethamine for the treatment of acute malaria in children of Papua New Guinea. II. Plasmodium vivax.
Topics: Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; New Guinea; Plasmodium vivax; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1982 |
The present status of malaria chemotherapy: mefloquine, a novel antimalarial.
Topics: Amodiaquine; Animals; Antimalarials; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Clinical Trials as Topic; Dogs; Drug Therapy, Combination; Erythrocytes; Female; Humans; Lethal Dose 50; Macaca mulatta; Malaria; Male; Mefloquine; Mice; Plasmodium berghei; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Protein Conformation; Pyrimethamine; Quinolines; Rats; Stereoisomerism; Swine | 1981 |
The treatment of malaria in glucose-6-phosphate dehydrogenase deficient patients in Sabah.
Topics: Adolescent; Adult; Anemia, Hemolytic; Antimalarials; Child; Chloroquine; Drug Combinations; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria; Male; Primaquine; Pyrimethamine; Sulfadoxine | 1981 |
Response of Plasmodium falciparum to chloroquine and Fansidar in vivo and chloroquine and amodiaquine in vitro in Uganda.
Topics: Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Follow-Up Studies; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Uganda | 1995 |
Severe morbidity among children in a trial malaria chemoprophylaxis with pyrimethamine or chloroquine in Ibarapa, Nigeria.
Topics: Age Factors; Child, Preschool; Chloroquine; Female; Follow-Up Studies; Humans; Incidence; Infant; Malaria; Male; Morbidity; Nigeria; Patient Admission; Primary Prevention; Pyrimethamine; Severity of Illness Index | 1993 |
Specific and nonspecific responses to Plasmodium falciparum blood-stage parasites and observations on the gametocytemia in schoolchildren living in a malaria-endemic area of Mozambique.
Topics: Adolescent; Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Blotting, Western; C-Reactive Protein; Child; Chloroquine; Computer Simulation; Drug Combinations; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Haptoglobins; Humans; Luminescent Measurements; Malaria, Falciparum; Models, Biological; Mozambique; Parasitemia; Plasmodium falciparum; Prevalence; Pyrimethamine; Recombinant Proteins; Sulfadoxine | 1995 |
In vivo sensitivity of Plasmodium falciparum to chloroquine, amodiaquine and sulfadoxine-pyrimethamine in western Uganda.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Uganda | 1994 |
Prevention of Plasmodium falciparum malaria by Fansimef and Lariam in the northeastern part of Thailand.
Topics: Adult; Animals; Antibodies, Protozoan; Blood; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Male; Mefloquine; Military Personnel; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand | 1993 |
The efficacy of antimalarial regimens containing sulfadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental Plasmodium falciparum infection among pregnant women in Malawi.
Topics: Analysis of Variance; Antimalarials; Chi-Square Distribution; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Malaria, Falciparum; Malawi; Parasitemia; Placenta Diseases; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Seasons; Sulfadoxine | 1994 |
Chloroquine and sulfadoxine/pyrimethamine sensitivity in Burkina Faso. In vivo sensitivity of Plasmodium falciparum to chloroquine and sulfadoxine/pyrimethamine in Burkina Faso.
Topics: Animals; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Urban Health | 1994 |
Response of falciparum malaria to chloroquine and three second line antimalarial drugs in a Kenyan coastal school age population.
Topics: Adolescent; Amodiaquine; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Kenya; Malaria, Falciparum; Microbial Sensitivity Tests; Pyrimethamine; Rural Health; Sulfadoxine; Sulfalene | 1993 |
Plasmodium falciparum sensitivity to antimalarials at Humera, northwestern Ethiopia.
Topics: Adolescent; Adult; Animals; Child; Chloroquine; Drug Combinations; Drug Resistance; Ethiopia; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1993 |
Resistance of Plasmodium falciparum to antimalarial drugs in Equatorial Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Equatorial Guinea; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1993 |
Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa.
Topics: Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Hemoglobin A; Humans; Infant; Kenya; Malaria, Falciparum; Malawi; Male; Pyrimethamine; Sulfadoxine | 1993 |
Recent military experience with malaria chemoprophylaxis.
Topics: Antimalarials; Australia; Chloroquine; Dapsone; Doxycycline; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Military Personnel; Primaquine; Pyrimethamine | 1993 |
Sulfadoxine/pyrimethamine or chloroquine/clindamycin treatment of Gabonese school children infected with chloroquine resistant malaria.
Topics: Adolescent; Animals; Anti-Bacterial Agents; Antimalarials; Child; Child, Preschool; Chloroquine; Clindamycin; Drug Combinations; Drug Resistance; Female; Gabon; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1995 |
A randomized trial of chloroquine, amodiaquine and pyrimethamine-sulphadoxine in Gambian children with uncomplicated malaria.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Gambia; Hematocrit; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Rural Health; Sulfadoxine; Treatment Failure | 1996 |
A randomised controlled trial to assess the relative efficacy of chloroquine, amodiaquine, halofantrine and Fansidar in the treatment of uncomplicated malaria in children.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Treatment Outcome | 1996 |
A comparative study of parenteral chloroquine, quinine and pyrimethamine-sulfadoxine in the treatment of Gambian children with complicated, non-cerebral malaria.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Data Interpretation, Statistical; Drug Combinations; Drug Resistance; Gambia; Humans; Infant; Infusions, Parenteral; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine; Time Factors | 1996 |
In vivo efficacy of chloroquine, halofantrine, pyrimethamine-sulfadoxine and qinghaosu (artesunate) in the treatment of malaria in Calabar, Nigeria.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Time Factors; Urban Health | 1996 |
Response of childhood malaria to chloroquine and Fansidar in an area of intermediate chloroquine resistance in Côte d'Ivoire.
Topics: Animals; Antimalarials; Body Temperature; Child; Child, Preschool; Chloroquine; Cote d'Ivoire; Drug Combinations; Drug Resistance, Microbial; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1996 |
A comparative study of the efficacies of chloroquine and a pyrimethamine-dapsone combination in clearing Plasmodium falciparum parasitaemia in school children in Tanzania.
Topics: Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Pyrimethamine; Random Allocation; Tanzania | 1996 |
Efficacy of artemether in severe falciparum malaria in African children.
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 1996 |
Chloroquine versus pyrimethamine/sulphadoxine in the treatment of uncomplicated P. falciparum malaria in northern Kenya.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Infant; Kenya; Malaria, Falciparum; Male; Pyrimethamine; Rural Health; Sulfadoxine | 1997 |
Treatment of chloroquine-resistant malaria using pyrimethamine in combination with berberine, tetracycline or cotrimoxazole.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antimalarials; Berberine; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Prospective Studies; Pyrimethamine; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination | 1997 |
The differing impact of chloroquine and pyrimethamine/sulfadoxine upon the infectivity of malaria species to the mosquito vector.
Topics: Animals; Anopheles; Antimalarials; Carrier State; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Insect Vectors; Malaria; Malaria, Falciparum; Mice; Mozambique; Plasmodium berghei; Plasmodium falciparum; Prevalence; Pyrimethamine; Risk Factors; Sulfadoxine | 1998 |
Chloroquine in Africa: critical assessment and recommendations for monitoring and evaluating chloroquine therapy efficacy in sub-Saharan Africa.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Monitoring; Drug Resistance; Female; Humans; Infant; Kenya; Malaria, Falciparum; Malawi; Male; Parasitemia; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Failure; Zambia | 1998 |
Response of falciparum malaria to different antimalarials in Myanmar.
Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Mefloquine; Myanmar; Pyrimethamine; Sulfadoxine | 1999 |
Atovaquone-proguanil compared with chloroquine and chloroquine-sulfadoxine-pyrimethamine for treatment of acute Plasmodium falciparum malaria in the Philippines.
Topics: Antimalarials; Atovaquone; Chloroquine; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Malaria, Falciparum; Naphthoquinones; Philippines; Proguanil; Pyrimethamine; Sulfadoxine | 1999 |
Population structure of recrudescent Plasmodium falciparum isolates from western Uganda.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antigens, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Merozoite Surface Protein 1; Middle Aged; Parasitemia; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Uganda | 1999 |
A community perspective on the efficacy of malaria treatment options for children in Lundazi district, Zambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Services; Drug Combinations; Female; Health Education; Health Services Accessibility; Humans; Malaria; Male; Patient Acceptance of Health Care; Pyrimethamine; Sulfadoxine; Treatment Outcome; Zambia | 1999 |
Assessment of therapeutic response of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in an area of low malaria transmission in Colombia.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Colombia; Disease Transmission, Infectious; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Failure | 1999 |
Monitoring efficacy of commonly used antimalarials by a 14-day in-vivo test in a new settler's camp in endemic zone at Cox's Bazar.
Topics: Adolescent; Adult; Antimalarials; Bangladesh; Child; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Prospective Studies; Pyrimethamine; Sulfadoxine; Transients and Migrants; Treatment Failure | 1998 |
Comparative efficacy of chloroquine plus chlorpheniramine alone and in a sequential combination with sulfadoxine-pyrimethamine, for the treatment of acute, uncomplicated, falciparum malaria in children.
Topics: Animals; Antimalarials; Antipruritics; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Administration Schedule; Drug Therapy, Combination; Fever; Germ Cells; Humans; Infant; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2000 |
A randomized, parallel-group study in Mumbai (Bombay), comparing chloroquine with chloroquine plus sulfadoxine-pyrimethamine in the treatment of adults with acute, uncomplicated, Plasmodium falciparum malaria.
Topics: Acute Disease; Adolescent; Adult; Aged; Antimalarials; Chloroquine; Cost of Illness; Cost-Benefit Analysis; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Health Care Costs; Humans; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2000 |
Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.
Topics: Adolescent; Animals; Anopheles; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Gambia; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2001 |
Atovaquone and proguani hydrochloride compared with chloroquine or pyrimethamine/sulfodaxine for treatment of acute Plasmodium falciparum malaria in Peru.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Middle Aged; Naphthoquinones; Peru; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2001 |
Efficacy of Sulphadoxine and Pyrimethamine, Doxycycline and their combination in the treatment of chloroquine resistant Falciparum Malaria.
Topics: Antimalarials; Chi-Square Distribution; Chloroquine; Doxycycline; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2001 |
Gametocytaemia in Senegalese children with uncomplicated falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Senegal; Sulfadoxine | 2001 |
Anemia of persistent malarial parasitemia in Nigerian children.
Topics: Anemia; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Nigeria; Parasitemia; Prospective Studies; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2001 |
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Gametogenesis; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Recurrence; Sulfadoxine; Treatment Failure; Treatment Outcome | 2002 |
Sulphadoxine/pyrimethamine: an appropriate first-line alternative for the treatment of uncomplicated falciparum malaria in Ghanaian children under 5 years of age.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Ghana; Humans; Infant; Malaria, Falciparum; Male; Outpatients; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2002 |
Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Area Under Curve; Child; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Philippines; Pyrimethamine; Recurrence; Sulfadoxine; Treatment Failure; Treatment Outcome | 2002 |
Sulfadoxine-pyrimethamine monotherapy in Tanzanian children gives rapid parasite clearance but slow fever clearance that is improved by chloroquine in combination therapy.
Topics: Acetaminophen; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Fever; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Prospective Studies; Pyrimethamine; Secondary Prevention; Sulfadoxine; Tanzania; Treatment Failure; Treatment Outcome | 2002 |
In vivo drug resistance of falciparum malaria in mining areas of Venezuela.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Health Promotion; Humans; Malaria, Falciparum; Male; Mining; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Failure; Treatment Outcome; Venezuela | 2002 |
Chloroquine and sulphadoxine-pyrimethamine efficacy for uncomplicated malaria treatment and haematological recovery in children in Bobo-Dioulasso, Burkina Faso during a 3-year period 1998-2000.
Topics: Anemia; Animals; Antimalarials; Burkina Faso; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Infant; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2002 |
Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations.
Topics: Adolescent; Adult; Animals; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Vivax; Male; Plasmodium vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2002 |
[Chemosensitivity of Plasmodium falciparum in Sainte Marie island, east coast of Madagascar: in vivo and in vitro studies].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation, Preclinical; Drug Monitoring; Drug Resistance; Female; Geography; Humans; Infant; Madagascar; Malaria, Falciparum; Male; Middle Aged; Parasitic Sensitivity Tests; Patient Selection; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2000 |
Therapeutic efficacy of chloroquine plus sulphadoxine/ pyrimethamine compared with monotherapy with either chloroquine or sulphadoxine/pyrimethamine in uncomplicated Plasmodium falciparum malaria in Laos.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sulfadoxine | 2003 |
Efficacy of chloroquine, sulfadoxine-pyrimethamine, and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria on the north coast of Peru.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Peru; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2003 |
Effects of chloroquine and sulfadoxine/pyrimethamine on gametocytes in patients with uncomplicated Plasmodium falciparum malaria in Colombia.
Topics: Adolescent; Adult; Animals; Antimalarials; Chi-Square Distribution; Child, Preschool; Chloroquine; Colombia; Drug Combinations; Female; Gametogenesis; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Statistics, Nonparametric; Sulfadoxine; Treatment Failure | 2002 |
Comparative efficacy of aminoquinoline-antifolate combinations for the treatment of uncomplicated falciparum malaria in Kampala, Uganda.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Single-Blind Method; Sulfadoxine; Treatment Outcome; Uganda | 2003 |
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Administration, Oral; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Ketotifen; Malaria, Falciparum; Male; Pyrimethamine; Recurrence; Sulfadoxine; Treatment Outcome | 2003 |
Plasmodium falciparum gametocytaemia in Nigerian children: before, during and after treatment with antimalarial drugs.
Topics: Age Factors; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2003 |
Assessing the efficacy of chloroquine and sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum malaria in the Democratic Republic of Congo.
Topics: Antimalarials; Child, Preschool; Chloroquine; Democratic Republic of the Congo; Drug Combinations; Drug Resistance; Hematocrit; Humans; Infant; Malaria, Falciparum; Parasitic Sensitivity Tests; Pyrimethamine; Sulfadoxine; Treatment Failure | 2003 |
Chloroquine versus sulfadoxine-pyrimethamine for treatment of Plasmodium falciparum malaria in Savannakhet Province, Lao People's Democratic Republic: an assessment of national antimalarial drug recommendations.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Health Planning Guidelines; Humans; Laos; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2003 |
Treatment of uncomplicated falciparum malaria in southern Vietnam: can chloroquine or sulfadoxine-pyrimethamine be reintroduced in combination with artesunate?
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Vietnam | 2003 |
Antipyretic, parasitologic, and immunologic effects of combining sulfadoxine/pyrimethamine with chloroquine or paracetamol for treating uncomplicated Plasmodium falciparum malaria.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antimalarials; Body Temperature; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Immunoglobulin G; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Severity of Illness Index; Sulfadoxine; Treatment Outcome | 2003 |
The efficacy of chloroquine, sulfadoxine-pyrimethamine and a combination of both for the treatment of uncomplicated Plasmodium falciparum malaria in an area of low transmission in western Uganda.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Middle Aged; Parasitemia; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2004 |
Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria.
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Mozambique; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2004 |
Efficacy of sulphadoxine-pyrimethamine alone or combined with amodiaquine or chloroquine for the treatment of uncomplicated falciparum malaria in Ugandan children.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2004 |
Antimalarial efficacy of sulfadoxine-pyrimethamine, amodiaquine and a combination of chloroquine plus sulfadoxine-pyrimethamine in Bundi Bugyo, western Uganda.
Topics: Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Developing Countries; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome; Uganda | 2004 |
Patterns of resistance and DHFR/DHPS genotypes of Plasmodium falciparum in rural Tanzania prior to the adoption of sulfadoxine-pyrimethamine as first-line treatment.
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Developing Countries; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Point Mutation; Pyrimethamine; Rural Health; Sulfadoxine; Tanzania; Tetrahydrofolate Dehydrogenase | 2004 |
Efficacy of combined chloroquine and sulfadoxine-pyrimethamine in uncomplicated Plasmodium falciparum malaria in Bangladesh.
Topics: Administration, Oral; Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2004 |
[Gametocyte levels in response to differing malaria treatments in two municipalities of Colombia].
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Colombia; Drug Combinations; Drug Therapy, Combination; Female; Gametogenesis; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2004 |
Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Sudan; Sulfadoxine; Treatment Outcome | 2004 |
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children.
Topics: Amodiaquine; Animals; Antimalarials; Carrier State; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Regression Analysis; Risk Factors; Sulfadoxine | 2004 |
Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Laos; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2004 |
Plasmodium falciparum hyperparasitaemia in children. Risk factors, treatment outcomes, and gametocytaemia following treatment.
Topics: Age Factors; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Gametogenesis; Humans; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Risk Factors; Sulfadoxine; Treatment Failure; Treatment Outcome | 2004 |
Clinical and parasitological response of Plasmodium falciparum to chloroquine and sulfadoxine/pyrimethamine in rural Uganda.
Topics: Adult; Animals; Antimalarials; Cell Proliferation; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Rural Population; Sulfadoxine; Treatment Outcome; Uganda | 2003 |
Efficacies of chloroquine, sulfadoxine-pyrimethamine and quinine in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Quinine; Sudan; Sulfadoxine; Treatment Failure; Treatment Outcome | 2004 |
Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Hemoglobins; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Myanmar; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2004 |
Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anemia; Birth Weight; Chemoprevention; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria; Mali; Multivariate Analysis; Parasitemia; Placenta Diseases; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Outcome; Pyrimethamine; Sulfadoxine | 2005 |
Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine.
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Developing Countries; Drug Combinations; Drug Resistance; Evidence-Based Medicine; Female; Health Policy; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sierra Leone; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana.
Topics: Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Ghana; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Patient Dropouts; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
A randomized comparison of sulphadoxine-pyrimethamine and combination of sulphadoxine pyrimethamine with chloroquine in the treatment of uncomplicated falciparum malaria in Eastern Sudan.
Topics: Adolescent; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sudan; Sulfadoxine | 2005 |
Comparison of sulfadoxine-pyrimethamine with and without chloroquine for uncomplicated malaria in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Body Weight; Child; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Male; Nigeria; Parasitemia; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2005 |
Therapeutic efficacy of antimalarial drugs along the eastern Indo-Nepal border: a cross-border collaborative study.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Nepal; Pyrimethamine; Sex Distribution; Sulfadoxine; Treatment Failure | 2005 |
Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of co-artemether.
Topics: Animals; Anopheles; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Gametogenesis; Humans; Infant; Malaria, Falciparum; Male; Mosquito Control; Plasmodium falciparum; Pyrimethamine; Single-Blind Method; Sulfadoxine | 2005 |
Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Protozoan Proteins; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2005 |
Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola.
Topics: Amodiaquine; Angola; Animals; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2005 |
Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Health Policy; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Sulfadoxine; Uganda | 2005 |
Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan.
Topics: Adolescent; Adult; Afghanistan; Aged; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasite Egg Count; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda.
Topics: Amodiaquine; Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Infections; Malaria; Male; Pyrimethamine; Risk Factors; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Uganda | 2005 |
Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Ghana; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.
Topics: Adolescent; Antimalarials; Artemether; Artemisinins; Artesunate; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Mefloquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2005 |
The drug sensitivities of Plasmodium falciparum in the Sonitpur district, Assam, India.
Topics: Adolescent; Adult; Age Factors; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; India; Infant; Malaria, Falciparum; Middle Aged; Plasmodium falciparum; Pyrimethamine; Rural Population; Sulfalene | 2005 |
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Polymerase Chain Reaction; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
[Evaluation of the therapeutic efficacy of amodiaquine versus chloroquine in the treatment of uncomplicated malaria in Abie, Côte-d'Ivoire].
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Cote d'Ivoire; Drug Combinations; Drug Resistance, Multiple; Endemic Diseases; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2005 |
A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; India; Infant; Malaria, Falciparum; Male; Mefloquine; Prospective Studies; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2006 |
Therapeutic efficacy of chloroquine in Plasmodium vivax from areas with different epidemiological patterns in India and their Pvdhfr gene mutation pattern.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Genes, Protozoan; Genotype; Humans; India; Malaria, Vivax; Male; Mutation; Plasmodium vivax; Prospective Studies; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome | 2006 |
Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance.
Topics: Adolescent; Adult; Aged; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endemic Diseases; Geography; Humans; Infant; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Mutation, Missense; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Failure; Treatment Outcome; Uganda | 2006 |
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Pyrimethamine; Recurrence; Sesquiterpenes; Sulfadoxine; Treatment Failure | 2006 |
Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda.
Topics: Administration, Oral; Adult; Antimalarials; Biological Availability; Chloroquine; Chromatography, High Pressure Liquid; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drugs, Generic; Female; Humans; Male; Probability; Pyrimethamine; Reference Values; Sensitivity and Specificity; Sulfadoxine; Therapeutic Equivalency; Uganda | 2006 |
Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Prospective Studies; Pyrimethamine; Recurrence; Sulfadoxine; Treatment Failure; Treatment Outcome | 2007 |
Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial.
Topics: Adult; Amodiaquine; Antimalarials; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Ghana; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2006 |
Return of chloroquine antimalarial efficacy in Malawi.
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Endemic Diseases; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Malawi; Male; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2006 |
Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Indonesia; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadoxine | 2006 |
Improved efficacy with amodiaquine instead of chloroquine in sulfadoxine/pyrimethamine combination treatment of falciparum malaria in Uganda: experience with fixed-dose formulation.
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2006 |
Thiamin deficiency and uncomplicated falciparum malaria in Laos.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Artesunate; Beriberi; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Enzyme Activation; Erythrocytes; Female; Humans; Infant; Laos; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thiamine Deficiency; Transketolase; Treatment Outcome | 2007 |
Sulfadoxine-pyrimethamine efficacy and selection of Plasmodium falciparum DHFR mutations in Burkina Faso before its introduction as intermittent preventive treatment for pregnant women.
Topics: Adolescent; Animals; Antimalarials; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Mutation; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Selection, Genetic; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Unusual pattern of Plasmodium falciparum drug resistance in the northwestern Peruvian Amazon region.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Peru; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2007 |
Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Infant; Madagascar; Malaria, Falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of Plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trial.
Topics: Adolescent; Adult; Afghanistan; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Female; Folic Acid Antagonists; Humans; Malaria, Vivax; Male; Middle Aged; Pakistan; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2007 |
A comparison of sulfadoxine-pyrimethamine with chloroquine and pyrimethamine for prevention of malaria in pregnant Nigerian women.
Topics: Adult; Animals; Antimalarials; Birth Weight; Chloroquine; Drug Combinations; Female; Hematocrit; Humans; Infant, Newborn; Malaria, Falciparum; Nigeria; Parasitemia; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2007 |
Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union.
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Comoros; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2007 |
Dramatically decreased therapeutic efficacy of chloroquine and sulfadoxine-pyrimethamine, but not mefloquine, in southern Benin.
Topics: Administration, Oral; Animals; Antigens, Protozoan; Antimalarials; Benin; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Merozoite Surface Protein 1; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2007 |
Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern Afghanistan.
Topics: Adolescent; Afghanistan; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Endemic Diseases; Humans; Malaria, Falciparum; Malaria, Vivax; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2007 |
Home-based management of fever and malaria treatment practices in Uganda.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Services; Drug Combinations; Drug Therapy, Combination; Fever; Health Knowledge, Attitudes, Practice; Home Nursing; Humans; Malaria; Mothers; Outcome Assessment, Health Care; Patient Compliance; Pyrimethamine; Rural Health; Sulfadoxine; Surveys and Questionnaires; Uganda | 2007 |
Comparison of the therapeutic efficacy of chloroquine and sulphadoxine-pyremethamine in children and pregnant women.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Malaria, Falciparum; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Treatment Failure | 2007 |
Pharmacokinetics and efficacy of piperaquine and chloroquine in Melanesian children with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinolines; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 2008 |
Low efficacy of amodiaquine or chloroquine plus sulfadoxine-pyrimethamine against Plasmodium falciparum and P. vivax malaria in Papua New Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sulfadoxine | 2007 |
Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa.
Topics: Analysis of Variance; Anemia; Animals; Antimalarials; Artemisinins; Artesunate; Benin; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Infant; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Respiratory Tract Infections; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2007 |
[Randomized clinical trial of two malaria prophylaxis regimens for pregnant women in Faladie, Mali].
Topics: Adult; Anemia; Antimalarials; Chloroquine; Drug Combinations; Endemic Diseases; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria, Falciparum; Mali; Placenta Diseases; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Sulfadoxine | 2007 |
[Comparative impact of three malaria preventive regimens during pregnancy on maternal anemia due to malaria in Burkina Faso].
Topics: Adult; Anemia; Antimalarials; Burkina Faso; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Prevalence; Pyrimethamine; Rural Population; Sulfadoxine | 2008 |
Efficacy of intermittent preventive treatment of malaria with sulphadoxine-pyrimethamine in preventing anaemia in pregnancy among Nigerian women.
Topics: Adolescent; Adult; Anemia; Antimalarials; Chloroquine; Drug Combinations; Female; Humans; Malaria; Nigeria; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Sulfadoxine; Young Adult | 2008 |
[Efficacy of the amodiaquine+sulfadoxine-pyrimethamine combination and of chloroquine for the treatment of malaria in Córdoba, Colombia, 2006].
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Colombia; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Female; Humans; Malaria; Male; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2008 |
A community effectiveness trial of strategies promoting intermittent preventive treatment with sulphadoxine-pyrimethamine in pregnant women in rural Burkina Faso.
Topics: Adolescent; Adult; Antimalarials; Burkina Faso; Chloroquine; Drug Combinations; Female; Health Promotion; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
A trial of combination antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Humans; Infant; Kaplan-Meier Estimate; Lumefantrine; Malaria, Falciparum; Malaria, Vivax; Male; Proportional Hazards Models; Pyrimethamine; Quinolines; Recurrence; Sulfadoxine | 2008 |
Short report: comparison of chlorproguanil-dapsone with a combination of sulfadoxine-pyrimethamine and chloroquine in children with malaria in northcentral Nigeria.
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2009 |
In vivo selection of Plasmodium falciparum parasites carrying the chloroquine-susceptible pfcrt K76 allele after treatment with artemether-lumefantrine in Africa.
Topics: Alleles; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Humans; Malaria, Falciparum; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Selection, Genetic; Sulfadoxine | 2009 |
Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali.
Topics: Amodiaquine; Animals; Antigens, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genes, Protozoan; Genetic Markers; Genotype; Humans; Infant; Malaria, Falciparum; Male; Mali; Merozoite Surface Protein 1; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2009 |
Artemisinin-naphthoquine combination (ARCO) therapy for uncomplicated falciparum malaria in adults of Papua New Guinea: a preliminary report on safety and efficacy.
Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Blood; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthoquinones; Papua New Guinea; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2009 |
Placental malaria and low birth weight in pregnant women living in a rural area of Burkina Faso following the use of three preventive treatment regimens.
Topics: Adult; Animals; Antimalarials; Burkina Faso; Chemoprevention; Chloroquine; Drug Combinations; Female; Fetal Blood; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria, Falciparum; Placenta; Placenta Diseases; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Rural Population; Sulfadoxine; Treatment Outcome; Young Adult | 2009 |
Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial.
Topics: Anemia, Sickle Cell; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Malaria; Male; Parasitemia; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2009 |
Active malaria morbidity management has limited impact on height status of preschool Senegalese children.
Topics: Antimalarials; Body Height; Child, Preschool; Chloroquine; Drug Combinations; Female; Growth Disorders; Humans; Infant; Malaria; Male; Pyrimethamine; Senegal; Sulfadoxine | 2010 |
Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Artemisinins; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Follow-Up Studies; Gametogenesis; Humans; Infant; Lumefantrine; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfalene; Treatment Outcome | 2010 |
A comparison of iron and folate with folate alone in hematologic recovery of children treated for acute malaria.
Topics: Anemia; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Folic Acid; Humans; Infant; Iron; Malaria; Male; Nigeria; Pyrimethamine; Sulfadoxine | 2010 |
Prevention of malaria during pregnancy: assessing the effect of the distribution of IPTp through the national policy in Benin.
Topics: Adult; Antimalarials; Benin; Chloroquine; Drug Combinations; Female; Health Policy; HIV Infections; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria; Maternal Age; Mefloquine; Multivariate Analysis; Placenta; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Risk Factors; Sulfadoxine; Young Adult | 2011 |
Efficacy of chloroquine and sulphadoxine-pyrimethamine either alone or in combination before introduction of ACT as first-line therapy in uncomplicated Plasmodium falciparum malaria in Jalpaiguri District, West Bengal, India.
Topics: Adolescent; Adult; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; India; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2011 |
Effect of transmission reduction by insecticide-treated bednets (ITNs) on antimalarial drug resistance in western Kenya.
Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Insecticide-Treated Bednets; Kenya; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Multivariate Analysis; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Young Adult | 2011 |
Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Pakistan; Patient Selection; Plasmodium falciparum; Polymerase Chain Reaction; Primaquine; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2012 |
Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial.
Topics: Adult; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria; Papua New Guinea; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Single-Blind Method; Sulfadoxine; Young Adult | 2015 |
Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission.
Topics: Adult; Antibodies, Protozoan; Antimalarials; Azithromycin; Chloroquine; Drug Combinations; Erythrocytes; Female; Humans; Malaria, Falciparum; Papua New Guinea; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Young Adult | 2015 |
Efficacy and Safety of Azithromycin-Chloroquine versus Sulfadoxine-Pyrimethamine for Intermittent Preventive Treatment of Plasmodium falciparum Malaria Infection in Pregnant Women in Africa: An Open-Label, Randomized Trial.
Topics: Adolescent; Adult; Azithromycin; Chloroquine; Drug Combinations; Female; Humans; Infant, Newborn; Intention to Treat Analysis; Malaria, Falciparum; Pregnancy; Pregnancy Outcome; Pyrimethamine; Sulfadoxine; Treatment Outcome; Young Adult | 2016 |
Placental but Not Peripheral Plasmodium falciparum Infection During Pregnancy Is Associated With Increased Risk of Malaria in Infancy.
Topics: Chloroquine; Drug Combinations; Female; Follow-Up Studies; Humans; Infant; Logistic Models; Longitudinal Studies; Malaria, Falciparum; Multivariate Analysis; Placenta; Placenta Diseases; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Risk Factors; Sulfadoxine | 2017 |
Chloroquine as weekly chemoprophylaxis or intermittent treatment to prevent malaria in pregnancy in Malawi: a randomised controlled trial.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Female; Humans; Infant, Newborn; Malaria; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2018 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
788 other study(ies) available for pyrimethamine and chloroquine
| Article | Year |
|---|---|
Folate antagonists. 15. 2,3-Diamino-6-(2-naphthylsulfonyl)quinazoline and related 2,4-diamino-6-[(phenyl and naphthyl)sulfinyl and sulfonyl]quinazolines, a potent new class of antimetabolites with phenomenal antimalarial activity.
Topics: Animals; Antimalarials; Bacteria; Chemical Phenomena; Chemistry; Chickens; Drug Resistance; Folic Acid Antagonists; Haplorhini; Malaria; Mice; Plasmodium; Quinazolines | 1979 |
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Acid Antagonists; Malaria; Mice; Plasmodium berghei; Triazines | 1977 |
Structure-activity relationships of novel anti-malarial agents. Part 2: cinnamic acid derivatives.
Topics: Animals; Antimalarials; Cinnamates; Combinatorial Chemistry Techniques; Inhibitory Concentration 50; Microbial Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2001 |
Phenoxypropoxybiguanides, prodrugs of DHFR-inhibiting diaminotriazine antimalarials.
Topics: Animals; Antimalarials; Drug Evaluation, Preclinical; Female; Folic Acid Antagonists; Guanidines; Malaria; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Proguanil; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Triazines | 2001 |
Structure-activity relationships of novel anti-malarial agents. Part 3: N-(4-acylamino-3-benzoylphenyl)-4-propoxycinnamic acid amides.
Topics: Amides; Animals; Antimalarials; Benzophenones; Cinnamates; Humans; Inhibitory Concentration 50; Phenylacetates; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Structure-activity relationships of novel anti-malarial agents. Part 4: N-(3-benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides.
Topics: Acrylamides; Animals; Antimalarials; Drug Resistance; Hydrogen Bonding; Indicators and Reagents; Plasmodium falciparum; Structure-Activity Relationship | 2002 |
Structure-activity relationships of novel anti-malarial agents: part 5. N-(4-acylamino-3-benzoylphenyl)-[5-(4-nitrophenyl)-2-furyl]acrylic acid amides.
Topics: Acrylates; Animals; Antimalarials; Drug Resistance, Multiple; Erythrocytes; Furans; Humans; Indicators and Reagents; Plasmodium falciparum; Structure-Activity Relationship | 2003 |
Structure-activity relationships of novel anti-malarial agents. Part 6: N-(4-arylpropionylamino-3-benzoylphenyl)-[5-(4-nitrophenyl)-2-furyl]acrylic acid amides.
Topics: Amides; Animals; Antimalarials; Benzophenones; Furans; Nitro Compounds; Plasmodium falciparum; Stereoisomerism; Structure-Activity Relationship | 2003 |
Structure-activity relationships of novel anti-malarial agents. Part 7: N-(3-benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides with polar moieties.
Topics: Acrylates; Alkyl and Aryl Transferases; Amides; Animals; Antimalarials; Enzyme Inhibitors; Farnesyltranstransferase; Furans; Hydrogen Bonding; Indicators and Reagents; Plasmodium falciparum; Structure-Activity Relationship | 2003 |
Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.
Topics: Alkyl and Aryl Transferases; Animals; Antimalarials; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Farnesyltranstransferase; Female; Humans; Malaria; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Plasmodium berghei; Plasmodium falciparum; Protein Prenylation; Quinolones; Rats; Structure-Activity Relationship | 2005 |
High-throughput Plasmodium falciparum growth assay for malaria drug discovery.
Topics: Animals; Biological Assay; Child, Preschool; DNA, Protozoan; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; Humans; Indoles; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy | 2007 |
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.
Topics: Animals; Antimalarials; Benzothiazoles; Diamines; Drug Evaluation, Preclinical; Erythrocytes; Fluorescent Dyes; Humans; Hypoxanthine; Organic Chemicals; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Anti-malarial activity of N6-modified purine analogues.
Topics: Animals; Antimalarials; Male; Mice; Molecular Structure; Plasmodium falciparum; Purines; Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2008 |
Antimalarial activity of a new stilbene glycoside from Parthenocissus tricuspidata in mice.
Topics: Animals; Antimalarials; Chloroquine; Glycosides; Malaria; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plasmodium berghei; Stilbenes; Treatment Outcome; Vitaceae | 2008 |
Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisinin against Plasmodium falciparum in vitro.
Topics: Animals; Antimalarials; Artemisinins; Chalcone; Drug Combinations; Drug Synergism; Erythrocytes; Hemeproteins; Hemolysis; Humans; Parasitic Sensitivity Tests; Plasmodium falciparum | 2009 |
In vitro chemosensitization of Plasmodium falciparum to antimalarials by verapamil and probenecid.
Topics: Adjuvants, Pharmaceutic; Animals; Antimalarials; Parasitic Sensitivity Tests; Plasmodium falciparum; Probenecid; Verapamil | 2009 |
Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines.
Topics: Aniline Compounds; Animals; Antimalarials; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Leishmania donovani; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship; Toxoplasma | 2009 |
Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Disease Models, Animal; Erythrocytes; Humans; Interleukin Receptor Common gamma Subunit; Kinetics; Malaria, Falciparum; Mice; Mice, Inbred NOD; Mice, SCID; Pyridones; Pyrimethamine | 2009 |
Original quinazoline derivatives displaying antiplasmodial properties.
Topics: Aniline Compounds; Animals; Antiprotozoal Agents; Cell Line; Drug Design; Humans; Inhibitory Concentration 50; Leishmania donovani; Phosphotransferases; Plasmodium falciparum; Quinazolines; Toxoplasma | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug candidate.
Topics: Administration, Oral; Animals; Antimalarials; Biological Availability; Drug Resistance; Female; Folic Acid Antagonists; Humans; In Vitro Techniques; Malaria; Malaria, Falciparum; Male; Mice; Models, Molecular; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinazolines; Rats; Rats, Wistar; Tetrahydrofolate Dehydrogenase | 2010 |
Spiroindolones, a potent compound class for the treatment of malaria.
Topics: Adenosine Triphosphatases; Animals; Antimalarials; Cell Line; Drug Discovery; Drug Resistance; Erythrocytes; Female; Genes, Protozoan; Humans; Indoles; Malaria; Male; Mice; Models, Molecular; Mutant Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium berghei; Plasmodium falciparum; Plasmodium vivax; Protein Synthesis Inhibitors; Protozoan Proteins; Rats; Rats, Wistar; Spiro Compounds | 2010 |
In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones.
Topics: Aminoquinolines; Antimalarials; Chalcones; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Models, Molecular; Plasmodium falciparum; Structure-Activity Relationship | 2011 |
Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.
Topics: Animals; Antimalarials; Dihydroorotate Dehydrogenase; Disease Models, Animal; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Malaria; Mice; Microsomes, Liver; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Plasmodium berghei; Plasmodium falciparum; Protein Binding; Pyrimidines; Solubility; Structure-Activity Relationship; Triazoles | 2011 |
Antimalarial pyrido[1,2-a]benzimidazoles.
Topics: Administration, Oral; Animals; Antimalarials; Benzimidazoles; Drug Resistance, Multiple; Humans; In Vitro Techniques; Injections, Intraperitoneal; L Cells; Malaria; Male; Mice; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2011 |
Imidazolopiperazines: hit to lead optimization of new antimalarial agents.
Topics: Amino Acids; Aniline Compounds; Animals; Antimalarials; Benzene Derivatives; Cell Line; Drug Resistance; Female; Humans; Imidazoles; Inhibitory Concentration 50; Malaria; Mice; Mice, Inbred BALB C; Piperazines; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship | 2011 |
Targeting the human malaria parasite Plasmodium falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series.
Topics: Animals; Antimalarials; Cell Line; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Plasmodium falciparum; Quinazolines; Structure-Activity Relationship | 2011 |
4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium falciparum.
Topics: Antimalarials; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Inhibitory Concentration 50; Mutagenicity Tests; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinazolines; Toxoplasma | 2011 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites | 2011 |
Discovery of a new antileishmanial hit in 8-nitroquinoline series.
Topics: Animals; Antiprotozoal Agents; Drug Discovery; Hep G2 Cells; Humans; Leishmania donovani; Life Cycle Stages; Mice; Nitroquinolines | 2012 |
Synthesis, characterization and antimalarial activity of quinoline-pyrimidine hybrids.
Topics: Animals; Antimalarials; Cell Survival; CHO Cells; Cricetinae; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Pyrimidines; Quinolines | 2013 |
A Divergent SAR Study Allows Optimization of a Potent 5-HT2c Inhibitor to a Promising Antimalarial Scaffold.
Topics: | 2012 |
Novel 4-aminoquinoline-pyrimidine based hybrids with improved in vitro and in vivo antimalarial activity.
Topics: | 2012 |
Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.
Topics: Animals; Antimalarials; Benzimidazoles; Biological Availability; Cell Line, Tumor; Cell Survival; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mice; Plasmodium falciparum; Small Molecule Libraries; Structure-Activity Relationship | 2014 |
N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
Topics: Aminopyridines; Animals; Antimalarials; Benzimidazoles; Hepatocytes; Humans; Malaria; Mice, SCID; Microsomes, Liver; Plasmodium berghei; Plasmodium falciparum; Rats; Structure-Activity Relationship | 2014 |
4-Aminoquinoline-pyrimidine hybrids: synthesis, antimalarial activity, heme binding and docking studies.
Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Cell Line; Heme; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines | 2015 |
Synthesis and biological evaluation of adamantane-based aminophenols as a novel class of antiplasmodial agents.
Topics: Adamantane; Aminophenols; Animals; Antimalarials; Cell Line; Humans; Plasmodium falciparum | 2015 |
Synthesis and in vitro evaluation of novel 8-aminoquinoline-pyrazolopyrimidine hybrids as potent antimalarial agents.
Topics: Aminoquinolines; Antimalarials; Humans; Malaria, Falciparum; Molecular Docking Simulation; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrazoles; Pyrimidines; Structure-Activity Relationship | 2015 |
Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium.
Topics: Animals; Antimalarials; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Erythrocytes; Hep G2 Cells; Humans; Liver; Malaria; Male; Mice; Parasitemia; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Trophozoites | 2015 |
Design, synthesis and biological evaluation of quinazoline derivatives as anti-trypanosomatid and anti-plasmodial agents.
Topics: Administration, Oral; Animals; Antimalarials; Antiprotozoal Agents; Chlorocebus aethiops; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Leishmania major; Malaria; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium vivax; Quinazolines; Structure-Activity Relationship; Trypanosoma cruzi; Vero Cells | 2015 |
A Developability-Focused Optimization Approach Allows Identification of in Vivo Fast-Acting Antimalarials: N-[3-[(Benzimidazol-2-yl)amino]propyl]amides.
Topics: Amides; Animals; Antimalarials; Benzamides; Benzimidazoles; Cell Proliferation; Cells, Cultured; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Humans; Malaria, Falciparum; Mice, Inbred NOD; Mice, SCID; Models, Molecular; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tissue Distribution | 2015 |
A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.
Topics: Animals; Antimalarials; Ether-A-Go-Go Potassium Channels; Humans; Liver; Malaria; Malaria, Falciparum; Mice; Plasmodium berghei; Plasmodium falciparum; Pyrazoles; Pyridines; Rats; Structure-Activity Relationship | 2015 |
Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.
Topics: Antimalarials; Chalcones; Chloroquine; Crystallography, X-Ray; Flavanones; Flavonoids; HEK293 Cells; Humans; Millettia; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Plasmodium falciparum | 2015 |
Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata.
Topics: Alkaloids; Animals; Annonaceae; Antimalarials; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; KB Cells; Malaria; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plasmodium berghei; Plasmodium falciparum; Vero Cells | 2016 |
Selective anti-malarial minor groove binders.
Topics: Antimalarials; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2016 |
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans.
Topics: Amines; Animals; Antimalarials; Drug Design; Drug Stability; Furans; Half-Life; Humans; Mice; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship | 2017 |
Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids.
Topics: Aminoquinolines; Animals; Antimalarials; Binding Sites; Cell Line; Heme; Humans; Molecular Docking Simulation; Multienzyme Complexes; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2017 |
Novel 2,3-disubstituted quinazoline-4(3H)-one molecules derived from amino acid linked sulphonamide as a potent malarial antifolates for DHFR inhibition.
Topics: Amino Acids; Antimalarials; Biological Availability; Enzyme Inhibitors; Folic Acid Antagonists; Plasmodium falciparum; Quinazolines; Sulfonamides; Tetrahydrofolate Dehydrogenase | 2017 |
N-Piperonyl substitution on aminoquinoline-pyrimidine hybrids: Effect on the antiplasmodial potency.
Topics: Aminoquinolines; Animals; Antimalarials; Chlorocebus aethiops; Dose-Response Relationship, Drug; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines; Structure-Activity Relationship; Vero Cells | 2017 |
Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
Topics: Antimalarials; Australia; Cell Survival; Chloroquine; Drug Resistance; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Conformation; Myrtaceae; Plant Extracts; Plasmodium falciparum; Sesquiterpenes | 2017 |
1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities.
Topics: Anti-Infective Agents; Antimalarials; Folic Acid Antagonists; Molecular Docking Simulation; Oxadiazoles; Spectrum Analysis; Triazoles | 2017 |
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
Topics: Amides; Animals; Antimalarials; Boron Compounds; Dogs; Female; Humans; Malaria; Malaria, Falciparum; Male; Mice; Plasmodium berghei; Plasmodium falciparum; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2017 |
Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antimalarials; Benzothiazoles; Cell Survival; Computer Simulation; Dose-Response Relationship, Drug; Folic Acid Antagonists; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Plasmodium falciparum; Quantum Theory; Schizosaccharomyces; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2017 |
Ionic liquid mediated stereoselective synthesis of alanine linked hybrid quinazoline-4(3H)-one derivatives perturbing the malarial reductase activity in folate pathway.
Topics: Alanine; Animals; Antimalarials; Caco-2 Cells; Catalysis; Chlorocebus aethiops; Dose-Response Relationship, Drug; Enzyme Inhibitors; Folic Acid; Humans; Ionic Liquids; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinazolinones; Stereoisomerism; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Vero Cells | 2017 |
A minimalistic approach to develop new anti-apicomplexa polyamines analogs.
Topics: Antiparasitic Agents; Apicomplexa; Dose-Response Relationship, Drug; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Polyamines; Structure-Activity Relationship; Toxoplasma | 2018 |
Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana.
Topics: Antimalarials; Australia; Biological Products; Indole Alkaloids; Magnetic Resonance Spectroscopy; Plant Extracts; Plant Leaves; Plasmodium falciparum; Rutaceae; Trees | 2017 |
Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis.
Topics: Alkaloids; Animals; Antimalarials; Antiparasitic Agents; Antiprotozoal Agents; Chagas Disease; Leishmania infantum; Leishmaniasis, Visceral; Parasitic Sensitivity Tests; Plasmodium falciparum; Porifera; Structure-Activity Relationship; Trypanosoma cruzi | 2018 |
Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-
Topics: | 2017 |
Discovery of Marinoquinolines as Potent and Fast-Acting Plasmodium falciparum Inhibitors with in Vivo Activity.
Topics: Animals; Antimalarials; Drug Design; Mice; Models, Molecular; Molecular Conformation; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Quinolines | 2018 |
Antiplasmodial β-Triketone-Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana.
Topics: Antimalarials; Flavanones; Flowers; HEK293 Cells; Humans; Ketones; Magnetic Resonance Spectroscopy; Molecular Structure; Myrtaceae; Plant Extracts; Trees | 2018 |
Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases.
Topics: Aminopeptidases; Antimalarials; Binding Sites; Catalytic Domain; Cell Survival; Drug Resistance; HEK293 Cells; Humans; Hydroxamic Acids; Molecular Docking Simulation; Plasmodium; Protease Inhibitors; Protozoan Proteins; Structure-Activity Relationship | 2019 |
Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing
Topics: | 2019 |
Acrotrione: An Oxidized Xanthene from the Roots of Acronychia pubescens.
Topics: Oxidation-Reduction; Plant Roots; Rutaceae; Xanthenes | 2019 |
Green synthesis, biological evaluation, molecular docking studies and 3D-QSAR analysis of novel phenylalanine linked quinazoline-4(3H)-one-sulphonamide hybrid entities distorting the malarial reductase activity in folate pathway.
Topics: Antimalarials; Humans; Malaria, Falciparum; Molecular Docking Simulation; Molecular Structure; Phenylalanine; Quantitative Structure-Activity Relationship; Sulfonamides | 2019 |
A new chemotype with promise against Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Humans; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2020 |
A Meroisoprenoid, Heptenolides, and
Topics: Annonaceae; Antimalarials; Flavanones; Flavonoids; HEK293 Cells; Humans; Molecular Structure; Plant Extracts; Plant Leaves; Plasmodium berghei; Plasmodium falciparum | 2020 |
Synthesis and efficacy of pyrvinium-inspired analogs against tuberculosis and malaria pathogens.
Topics: Antimalarials; Antitubercular Agents; Dose-Response Relationship, Drug; Malaria, Falciparum; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrvinium Compounds; Structure-Activity Relationship; Tuberculosis | 2020 |
Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship | 2021 |
Discovery and Structure-Activity Relationships of Quinazolinone-2-carboxamide Derivatives as Novel Orally Efficacious Antimalarials.
Topics: Administration, Oral; Animals; Antimalarials; Humans; Malaria, Falciparum; Mice; Molecular Structure; Plasmodium falciparum; Quinazolinones; Structure-Activity Relationship | 2021 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk | 1977 |
Development of effective antisporozoite immunity by natural bites of Plasmodium-berghei-infected mosquitoes in rats under prophylactic treatment with various drug regimens.
Topics: Animals; Antibodies; Chloroquine; Cross Reactions; Culicidae; Malaria; Plasmodium berghei; Primaquine; Pyrimethamine; Pyrithiamine; Rats; Spores; Vaccination | 1978 |
Persistence of drug-resistant malaria parasites.
Topics: Animals; Chloroquine; Drug Resistance; Malaria; Mice; Mutation; Plasmodium; Pyrimethamine | 1978 |
Plasmodium falciparum and Plasmodium vivax infections in the owl monkey (Aotus trivirgatus). II. Responses to chloroquine, quinine, and pyrimethamine.
Topics: Animals; Aotus trivirgatus; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Haplorhini; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine | 1978 |
Antimalarial activities of various 9-phenanthrenemethanols with special attention to WR-122,455 and WR-171,669.
Topics: Animals; Antimalarials; Chloroquine; Haplorhini; Humans; Malaria; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine | 1978 |
Studies on the 2,4-diamino-6-substituted quinazolines. II. Activities of selected derivatives against infections with various drug-susceptible and drug-resistant strains of Plasmodium falciparum and Plasmodium vivax in owl monkeys.
Topics: Animals; Aotus trivirgatus; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance, Microbial; Female; Haplorhini; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinazolines | 1979 |
Resistance to antimalarials by Plasmodium falciparum in Burma.
Topics: Antimalarials; Chloroquine; Drug Resistance; Humans; Malaria; Myanmar; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1977 |
Prevention and treatment of malaria.
Topics: Amodiaquine; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Trimethoprim | 1977 |
Experimental studies of the potentiation of proguanil and pyrimethamine by dapsone using Plasmodium berghei in white mice.
Topics: Animals; Chloroquine; Dapsone; Drug Synergism; Mice; Plasmodium berghei; Proguanil; Pyrimethamine | 1977 |
[Chloroquine resistant tropical malaria imported from Surinam].
Topics: Chloroquine; Drug Resistance; Female; Humans; Malaria; Middle Aged; Netherlands; Plasmodium falciparum; Pyrimethamine; Quinine; Suriname; Travel | 1977 |
The influence of acetylator phenotype on the response to sulfalene in individuals with chloroquine-resistant falciparum malaria.
Topics: Acetylation; Adult; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Male; Phenotype; Plasmodium falciparum; Pyrimethamine; Sulfalene; Sulfamethazine; Sulfanilamides | 1978 |
[Malaria; a summary].
Topics: Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine | 1978 |
A comparative study of malaria prophylaxis in peninsular Malaysia using chloroquine and a combination of sulphadoxine and pyrimethamine.
Topics: Adult; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Leukocyte Count; Malaria; Malaysia; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1978 |
The treatment of malaria.
Topics: Chloroquine; Drug Combinations; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1978 |
Falciparum malaria despite chemoprophylaxis.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1979 |
Treatment of falciparum malaria in Thai children.
Topics: Child; Child, Preschool; Chloroquine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Thailand | 1979 |
Drug-resistant falciparum malaria among the Mayongong Indians in the Brazilian Amazon.
Topics: Adolescent; Adult; Brazil; Child; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1979 |
Malaria in Australia.
Topics: Australia; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1979 |
Studies on Plasmodium falciparum in continuous cultivation. I. The effect of chloroquine and pyrimethamine on parasite growth and viability.
Topics: Animals; Aotus trivirgatus; Chloroquine; Dose-Response Relationship, Drug; Erythrocytes; Humans; Plasmodium falciparum; Pyrimethamine | 1979 |
Possible chloroquine-resistant Plasmodium falciparum in Nigeria.
Topics: Chloroquine; Drug Resistance; Drug Therapy, Combination; Erythrocytes; Humans; Malaria; Male; Middle Aged; Nigeria; Plasmodium falciparum; Pyrimethamine; Sulfadiazine | 1979 |
Chemotherapy of falciparum malaria: regional differences in responsiveness to treatment.
Topics: Adult; Africa, Central; Africa, Western; Asia, Southeastern; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Indian Ocean Islands; Japan; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfamonomethoxine | 1979 |
Chloroquine resistance in P. falciparum in Assam State.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; India; Infant; Malaria; Plasmodium falciparum; Primaquine; Pyrimethamine | 1979 |
Response to chloroquine with and without pyrimethamine in Plasmodium falciparum in West Bengal, Tripura, Mizoram, Manipur and Arunachal Pradesh.
Topics: Animals; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1979 |
Malaria--a red alert.
Topics: Aged; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Health Education; Humans; Malaria; Pyrimethamine; Quinine; Sulfadiazine; Tetracycline; Travel | 1979 |
Chemoprophylaxis of chloroquine-resistant malaria; an additional note.
Topics: Chloroquine; Drug Resistance; Humans; Malaria; Pyrimethamine; Sulfadoxine | 1979 |
Chemoprophylaxis of malaria.
Topics: Chloroquine; Drug Evaluation; Drug Resistance, Microbial; Malaria; Proguanil; Pyrimethamine | 1977 |
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronidazole; Middle Aged; Minocycline; Pentamidine; Pyrimethamine; Recurrence; Sulfadiazine; Tetracycline; Time Factors | 1978 |
Chloroquine-resistant falciparum malaria from Irian Jaya (Indonesian New Guinea).
Topics: Amodiaquine; Chloroquine; Drug Resistance; Humans; Malaria; Male; Piperidines; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Quinolines | 1976 |
Studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in Peninsular Malaysia.
Topics: Child; Chloroquine; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaysia; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pyrimethamine | 1976 |
Chemoprophylaxis of malaria.
Topics: Adult; Antimalarials; Chloroquine; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine; Travel | 1976 |
A comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in Peninsular Malaysia.
Topics: Adult; Child; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium malariae; Pyrimethamine | 1976 |
Chemotherapy of Plasmodium vivax in Saimiri and Aotus models.
Topics: Administration, Oral; Animals; Chloroquine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Haplorhini; Malaria; Plasmodium vivax; Primaquine; Pyrimethamine; Recurrence; Splenectomy; Time Factors | 1975 |
Antiplasmodial efficacy of 2,4--diaminopyrimidine0sylfonamide combinations, especially against chloroquine-resistant malaria.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Folic Acid Antagonists; History, 20th Century; Humans; Lacticaseibacillus casei; Leucovorin; Malaria; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Sulfalene; Sulfonamides; Trimethoprim | 1975 |
[Chemotherapy and chemoprophylaxis of malaria (author's transl)].
Topics: Adult; Amodiaquine; Antimalarials; Asia, Southeastern; Central America; Child; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine; Sulfalene; Travel | 1976 |
[Prevention and therapy of malaria and amebiasis].
Topics: Acetamides; Amebiasis; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Emetine; Humans; Malaria; Nitroimidazoles; Protective Devices; Pyrimethamine; Sulfadoxine; Tetracycline | 1977 |
[Chemoprophylaxis of malaria].
Topics: Africa; Asia; Chloroquine; Humans; Hungary; Malaria; Proguanil; Pyrimethamine; South America | 1976 |
Letter: Prevention of chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Malaria; Plasmodium falciparum; Primaquine; Pyrimethamine; Pyrimidines; Sulfanilamides | 1975 |
Sulfadoxine and pyrimethamine in the treatment of falciparum malaria in Vietnam.
Topics: Adolescent; Adult; Blood; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides; Time Factors; Vietnam | 1975 |
Chloroquine resistance of Plasmodium falciparum in West Irian and East Kalimantan.
Topics: Adult; Chloroquine; Drug Resistance; Erythrocytes; Humans; Indonesia; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Spectrophotometry; Sulfadoxine | 1975 |
Some effects of partial malaria suppression in Ugandan children during the first 3 years of life.
Topics: Antibodies; Child, Preschool; Chloroquine; Humans; Infant; Malaria; Plasmodium falciparum; Pyrimethamine; Uganda | 1975 |
Acetylator phenotype and response of individuals infected with a chloroquine-resistant strain of Plasmodium falciparum to sulfalene and pyrimethamine.
Topics: Acetylation; Adult; Chloroquine; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Male; Middle Aged; Phenotype; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Sulfalene; Sulfamethazine; Sulfanilamides; United States; Vietnam | 1975 |
Death from a severe case of Plasmodium falciparum in a Canadian.
Topics: Adult; Animals; Antimalarials; Cause of Death; Chloroquine; Drug Combinations; Female; Humans; Malaria, Falciparum; Multiple Organ Failure; Plasmodium falciparum; Pyrimethamine; Quinidine; Sulfadoxine; Travel | 1992 |
Sensitivity status of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine and sulfadoxine/pyrimethamine in a tribal population of District Sundargarh, Orissa.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1992 |
Incorporation of [3H]hypoxanthine by short-term cultured Theileria sergenti and its inhibition by drugs.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cattle; Cells, Cultured; Chloroquine; Diminazene; Dose-Response Relationship, Drug; Erythrocytes; Hypoxanthine; Hypoxanthines; Immune Sera; Pyrimethamine; Quinine; Theileria | 1992 |
Plasmodium falciparum: effect of chloroquine, halofantrine and pyrimethamine on the infectivity of gametocytes for Anopheles stephensi mosquitoes.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Insect Vectors; Phenanthrenes; Plasmodium falciparum; Pyrimethamine | 1992 |
A new model for testing gametocytocidal effects of some antimalarial drugs on Plasmodium falciparum in vitro.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; In Vitro Techniques; Models, Biological; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine | 1992 |
The combined effect of iron chelators and classical antimalarials on the in-vitro growth of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Synergism; Iron Chelating Agents; Plasmodium falciparum; Pyrimethamine; Quinine | 1992 |
Antimalarial drug sensitivity patterns in the western province of Zambia. Implications for the management of primary health care (PHC).
Topics: Adolescent; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sulfadoxine; Zambia | 1992 |
Efficacies of chloroquine, pyrimethamine/sulphadoxine and pyrimethamine/sulphalene against P. falciparum in northeastern Nigeria.
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Humans; Incidence; Infant; Malaria, Falciparum; Nigeria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfalene | 1992 |
Treatment of chloroquine-resistant malaria in African children: a cost-effectiveness analysis.
Topics: Africa; Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Cost-Benefit Analysis; Decision Trees; Drug Combinations; Drug Costs; Drug Resistance; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1992 |
In vitro sensitivity of southern African reference isolates of Plasmodium falciparum to chloroquine and pyrimethamine.
Topics: Africa, Southern; Animals; Chloroquine; Drug Resistance; Humans; Malaria; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine | 1991 |
A study of current practices in the treatment of malaria in industrial complexes in India.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Occupational Medicine; Plasmodium falciparum; Pyrimethamine; Sulfalene | 1991 |
[Prevention and treatment of malaria in expatriates living in Black Africa. Influence of chemoresistance. Investigations conducted in Brazzaville (Congo)].
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance, Microbial; Europe; Humans; Infant; Infant, Newborn; Malaria; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Resistance to antimalarials by Plasmodium falciparum in Arso PIR, Irian Jaya, Indonesia.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Indonesia; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1991 |
Pyrimethamine-sulfadoxine (Fansidar) resistance in a non-immune Kenyan--a case report.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Kenya; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1991 |
Problems of chloroquine-resistant P. falciparum in Nigeria: one antimalaria drugs' utilisation in metropolitan Calabar.
Topics: Adult; Animals; Chloroquine; Drug Resistance, Microbial; Educational Status; Female; Humans; Malaria; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Self Medication; Surveys and Questionnaires; Urban Population | 1991 |
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Butylated Hydroxytoluene; Chloroquine; Drug Resistance; Drugs, Chinese Herbal; Mefloquine; Molecular Structure; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Sesquiterpenes; Thailand | 1991 |
Application of a simplified in-vivo test system for determining chloroquine resistance in Plasmodium falciparum.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Chloroquine; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfalene | 1990 |
Activities of new acridone alkaloid derivatives against Plasmodium yoelii in vitro.
Topics: Acridines; Acridones; Alkaloids; Animals; Antimalarials; Cell Survival; Chloroquine; Erythrocytes; In Vitro Techniques; Leukemia L1210; Malaria; Male; Mice; Mice, Inbred ICR; Plasmodium yoelii; Pyrimethamine; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
[Imported fever in a 4-year-old boy].
Topics: Africa, Central; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Travel | 1990 |
Malaria prophylaxis in travellers to tropical Africa.
Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine; Travel | 1990 |
[Uncomplicated malaria attack in an area with high resistance to chloroquine. 3. The use of second-choice oral drug treatment].
Topics: Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1990 |
[Look systematically for malaria in exposed children].
Topics: Adoption; Animals; Child, Preschool; Chloroquine; Emigration and Immigration; Female; Humans; Infant; Malaria; Male; Plasmodium falciparum; Primaquine; Pyrimethamine; Sweden; Thailand; Tropical Climate | 1990 |
Efficacies of chloroquine and pyrimethamine-sulphadoxine in a Nigerian population with chloroquine resistant P. falciparum malaria.
Topics: Animals; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Nigeria; Plasmodium falciparum; Pyrimethamine; Rural Population; Sulfadoxine; Sulfanilamides | 1990 |
Isolated malaria outbreak in Somalia: role of chloroquine-resistant Plasmodium falciparum demonstrated in Balcad epidemic.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chloroquine; Disease Outbreaks; Dose-Response Relationship, Drug; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Regression Analysis; Somalia; Sulfadoxine | 1990 |
[Plasmodium falciparum drug resistance in the Congo. Evaluation of surveys carried out from 1985 to 1989].
Topics: Adolescent; Aminoquinolines; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Congo; Drug Combinations; Drug Resistance; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1990 |
Microscopic and flow cytophotometric analysis of parasitemia in cultures of Plasmodium falciparum vitally stained with Hoechst 33342--application to studies of antimalarial agents.
Topics: Antimalarials; Benzimidazoles; Chloroquine; Cyclosporins; DNA; Erythrocytes; Flow Cytometry; Fluorescent Dyes; Humans; Malaria; Microscopy, Fluorescence; Plasmodium falciparum; Pyrimethamine; Staining and Labeling | 1986 |
Prophage induction by 4 antimalaria drugs (daraprim, fansidar, nivaquine and camoquine) and in combination with aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Amodiaquine; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Escherichia coli; In Vitro Techniques; Lysogeny; Mutagenicity Tests; Pyrimethamine; Sulfadoxine | 1989 |
[Chloroquine-resistant Plasmodium falciparum malaria confirmed by semi-micro sensitivity test for chloroquine seen in a person returned from Nigeria to Japan].
Topics: Adult; Animals; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1989 |
Plasmodium vivax resistance to chloroquine?
Topics: Acute Disease; Animals; Antimalarials; Blood Specimen Collection; Chloroquine; Dapsone; Drug Administration Schedule; Drug Combinations; Drug Evaluation; Drug Resistance; Humans; Malaria; Male; Papua New Guinea; Plasmodium vivax; Pyrimethamine | 1989 |
Premature release of Plasmodium falciparum from swollen erythrocytes induced by some antimalarials.
Topics: Animals; Antimalarials; Artemisinins; Azure Stains; Cells, Cultured; Chloroquine; Erythrocyte Membrane; Erythrocytes; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes | 1989 |
[Experimental study of the action of antimalarial agents with respect to therapy in porphyria. Combined effect of chloroquine and pyrimethamine].
Topics: Chloroquine; Humans; Porphyrias; Porphyrins; Pyrimethamine; Saccharomyces cerevisiae | 1989 |
[Comparative efficacy of alternative treatments in Plasmodium falciparum infections in Zaire].
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Democratic Republic of the Congo; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1989 |
[A new model for testing substances affecting the synthesis of heme].
Topics: Chloroquine; Drug Evaluation, Preclinical; Heme; Porphyrins; Pyrimethamine; Saccharomyces cerevisiae | 1989 |
A focus of high degree chloroquine resistant P. falciparum in Mandla district (M.P.).
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; India; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfalene | 1989 |
Chloroquine resistance in Plasmodium falciparum in KwaZulu, 1983-1988.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Malaria; Plasmodium falciparum; Pyrimethamine; South Africa; Sulfadoxine; Sulfanilamides | 1989 |
Curative and preventive treatment of uncomplicated malaria in public health institutions in Cameroon.
Topics: Amodiaquine; Antimalarials; Cameroon; Child; Chloroquine; Drug Combinations; Female; Humans; Malaria; Medicine; Nurses; Physicians; Pregnancy; Public Health; Pyrimethamine; Quinine; Specialization; Sulfadoxine; Surveys and Questionnaires | 1989 |
Does chloroquine contribute to the risk of serious adverse reactions to fansidar?
Topics: Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Skin Diseases; Sulfadoxine; Sulfanilamides | 1985 |
Severe cutaneous adverse reactions to sulfadoxine-pyrimethamine in Switzerland.
Topics: Acute Disease; Antimalarials; Chloroquine; Drug Combinations; Drug Eruptions; Humans; Pyrimethamine; Sulfadoxine; Sulfanilamides; Switzerland; Travel | 1986 |
Failure of dapsone/pyrimethamine plus chloroquine against falciparum malaria in Papua New Guinea.
Topics: Adult; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Male; Papua New Guinea; Plasmodium falciparum; Pyrimethamine | 1988 |
Compliance with malaria chemoprophylaxis programmes in Zimbabwe.
Topics: Chloroquine; Dapsone; Humans; Malaria; Patient Compliance; Pyrimethamine; Zimbabwe | 1987 |
An unusual combination of phototoxicity and Stevens-Johnson syndrome due to antimalarial therapy.
Topics: Antimalarials; Child; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Male; Photosensitivity Disorders; Pyrimethamine; Stevens-Johnson Syndrome; Sulfadoxine; Sulfanilamides | 1989 |
Erythroderma resembling sézary syndrome after treatment with Fansidar and chloroquine.
Topics: Antimalarials; Chloroquine; Dermatitis, Exfoliative; Drug Combinations; Humans; Malaria; Male; Middle Aged; Pyrimethamine; Sulfadoxine; Sulfanilamides; Treponema pallidum | 1986 |
Severe cutaneous reactions among American travelers using pyrimethamine-sulfadoxine (Fansidar) for malaria prophylaxis.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Eruptions; Erythema Multiforme; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Stevens-Johnson Syndrome; Sulfadoxine; Sulfanilamides; Travel; United States | 1986 |
[Delay in emergence of resistance to pyronaridine phosphate in Plasmodium berghei].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Synergism; Mice; Naphthyridines; Plasmodium berghei; Pyrimethamine; Sulfadoxine | 1986 |
Need for malaria prophylaxis by travelers to areas with chloroquine-resistant Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Centers for Disease Control and Prevention, U.S.; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Travel; United States | 1986 |
Leads from the MMWR. Need for malaria prophylaxis by travelers to areas with chloroquine-resistant Plasmodium falciparum.
Topics: Africa; Antimalarials; Centers for Disease Control and Prevention, U.S.; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pyrimethamine; Sulfadoxine; Sulfanilamides; Travel; United States | 1986 |
Pigmentary changes in rat oral mucosa following antimalarial therapy.
Topics: Adrenocorticotropic Hormone; Animals; Chloroquine; Male; Melanocytes; Mouth Mucosa; Pigmentation Disorders; Pyrimethamine; Rats; Rats, Inbred Strains; Testosterone | 1986 |
Serial studies on the evolution of drug resistance in malaria in an area of east Africa: findings from 1979 up to 1986.
Topics: Age Factors; Amodiaquine; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Quinolines; Sulfadoxine; Tanzania | 1988 |
A rapid in vitro assay system using anti-bromodeoxyuridine for drug susceptibility of Plasmodium falciparum.
Topics: Animals; Bromodeoxyuridine; Chloroquine; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Plasmodium falciparum; Pyrimethamine; Quinine | 1988 |
Antagonism of chloroquine with other antimalarials.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Interactions; Drug Resistance; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sesquiterpenes; Sulfadoxine | 1988 |
[An imported case of malaria resistant to chloroquine].
Topics: Animals; Cameroon; Child; Child, Preschool; Chloroquine; Doxycycline; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Israel; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1988 |
Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Military Personnel; Papua New Guinea; Plasmodium falciparum; Plasmodium vivax; Proguanil; Pyrimethamine | 1988 |
The first report of Plasmodium falciparum resistant to chloroquine plus sulphadoxine/pyrimethamine in Rwanda.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Rwanda; Sulfadoxine; Sulfanilamides | 1988 |
[Chloroquine and fansidar resistance of Plasmodium falciparum now also in Ghana].
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Ghana; Humans; Malaria; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1988 |
Multiple drug resistant Plasmodium falciparum malaria in a pregnant indigenous Zambian woman.
Topics: Adult; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Erythromycin; Female; Humans; Malaria; Mefloquine; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1988 |
Death despite malaria prophylaxis.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1988 |
Idiosyncratic reaction resembling toxic epidermal necrolysis caused by chloroquine and maloprim.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Humans; Male; Middle Aged; Pyrimethamine; Stevens-Johnson Syndrome | 1988 |
Revised recommendations for preventing malaria in travelers to areas with chloroquine-resistant Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Eruptions; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Travel | 1985 |
Leads from the MMWR. Revised recommendations for preventing malaria in travelers to areas with chloroquine-resistant Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Eruptions; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Travel | 1985 |
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
Topics: Amodiaquine; Animals; Antimalarials; Butylated Hydroxytoluene; Chloroquine; Humans; Mefloquine; Parasitology; Phenanthrenes; Plasmodium falciparum; Pyridines; Pyrimethamine; Quinine; Quinolines; Thailand; Triazines | 1988 |
In vitro activity of pyronaridine against field isolates and reference clones of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Drug Resistance; Humans; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1988 |
Concurrent chloroquine and Fansidar resistance of Plasmodium falciparum: an imported case from Gabon.
Topics: Animals; Chloroquine; Drug Combinations; Drug Resistance; Gabon; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides | 1988 |
[Diagnosis of drug-resistant strains of Plasmodium falciparum].
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Plasmodium falciparum; Pyrimethamine; Reagent Kits, Diagnostic; Sulfadoxine; World Health Organization | 1987 |
Clinical evaluation of antimalarial regimens in Japan.
Topics: Animals; Antimalarials; Chloroquine; Drug Therapy, Combination; Humans; Japan; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Prognosis; Pyrimethamine; Quinine; Recurrence; Sulfonamides; Surveys and Questionnaires | 1987 |
Plasmodium falciparum in Kinshasa, Zaire: in vitro drug susceptibility studies.
Topics: Animals; Child; Chloroquine; Democratic Republic of the Congo; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine | 1987 |
[Pharmacoresistance of Plasmodium falciparum in Rwanda: an in vivo study].
Topics: Amodiaquine; Animals; Chloroquine; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Pyrimethamine; Rwanda; Sulfadoxine | 1987 |
A case of Plasmodium falciparum infection resistant to chloroquine.
Topics: Adult; Animals; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1987 |
The activity of drug combinations against established infections of rodent malaria.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Malaria; Mice; Plasmodium berghei; Plasmodium yoelii; Pyrimethamine; Sulfadoxine | 1987 |
[2 cases of multiresistant Plasmodium falciparum malaria contracted in Douala with atypical clinical presentation].
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Cameroon; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine | 1987 |
[Development of drug resistance in cases of P. falciparum malaria of African origin in a Parisian hospital. Comparison with field data and therapeutic consequences].
Topics: Africa; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; France; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Travel | 1987 |
Compared response to chloroquine, fansidar, quinine, and quinidine slow release of infections with Plasmodium falciparum in the Kivu region of Zaire.
Topics: Animals; Antimalarials; Chloroquine; Delayed-Action Preparations; Democratic Republic of the Congo; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinidine; Quinine; Sulfadoxine; Sulfanilamides | 1987 |
Report of a case of P. falciparum malaria resistant to chloroquine and combination of sulfalene and pyrimethamine in Delhi.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfalene; Sulfanilamides | 1987 |
Comparative efficacy of alternative primary therapies for Plasmodium falciparum infections in Malawi.
Topics: Amodiaquine; Animals; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Malawi; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1987 |
[2 years' experience with combined therapy of symptomatic liver porphyria using pyrimethamine and chloroquine].
Topics: Adult; Chloroquine; Drug Therapy, Combination; Female; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Pyrimethamine | 1988 |
Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes.
Topics: Antimalarials; Candida; Cells, Cultured; Chloroquine; Drug Administration Schedule; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mefloquine; Protein Biosynthesis; Pyrimethamine; Quinine; Quinolines; Tuberculin | 1987 |
Reduced efficacy of chemotherapy of Plasmodium chabaudi in T cell-deprived mice.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Lymphocyte Depletion; Malaria; Mice; Mice, Inbred CBA; Pyrimethamine; Quinine; T-Lymphocytes | 1987 |
A model for testing compounds influencing porphyrin synthesis.
Topics: Cell Membrane; Chloroquine; Chromatography, High Pressure Liquid; Kinetics; Models, Biological; Permeability; Porphyrins; Pyrimethamine; Saccharomyces cerevisiae | 1986 |
Adaptation of the Indochina I/CDC strain of Plasmodium falciparum to the squirrel monkey (Saimiri sciureus).
Topics: Animals; Aotus trivirgatus; Cebidae; Chloroquine; Disease Models, Animal; Drug Resistance; Malaria; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Saimiri; Splenectomy; Sulfadoxine | 1986 |
Sensitivity in vivo of Plasmodium falciparum to chloroquine and pyrimethamine/sulfadoxine in a coastal area of Tanzania.
Topics: Adolescent; Child; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Tanzania; Time Factors | 1986 |
Imported cases of chloroquine-resistant falciparum malaria in Iran.
Topics: Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Iran; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadiazine; Sulfadoxine; Travel | 1986 |
[Malaria prevention. Risk of infection in relation to preventive measures].
Topics: Adult; Africa; Antimalarials; Chloroquine; Drug Combinations; Female; Germany, West; Humans; India; Malaria; Male; Middle Aged; Patient Compliance; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sulfadoxine; Travel | 1986 |
Serious problems with antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine | 1986 |
Epidemiology of emergence and spread of drug-resistant falciparum malaria in Southeast Asia.
Topics: Anopheles; Asia, Southeastern; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Insect Vectors; Malaria; Plasmodium falciparum; Pyrimethamine; Retrospective Studies; Sulfadoxine; Sulfanilamides | 1986 |
The efficacy of artemether (qinghaosu) in Plasmodium falciparum and P. vivax in Burma.
Topics: Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrans; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 1986 |
[Chloroquine-resistant malignant malaria in Hainan Island: report of 10 years' study].
Topics: China; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1986 |
Failures of combined chloroquine and Fansidar prophylaxis in American travelers to East Africa.
Topics: Adult; Aged; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Kenya; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Tanzania; Travel | 1986 |
Analogues of N-benzyloxydihydrotriazines: in vitro antimalarial activity against Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 1986 |
Concurrent chloroquine- and Fansidar-resistant Plasmodium falciparum: an imported case into Zimbabwe.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Zimbabwe | 1986 |
Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia.
Topics: Antimalarials; Asia, Southeastern; Cambodia; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Pacific Islands; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand | 1986 |
Chloroquine-resistant falciparum malaria from East Africa.
Topics: Adult; Africa, Eastern; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Male; Mefloquine; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1986 |
A combination of sulfamonomethoxine and pyrimethamine versus other drugs for the treatment of malaria.
Topics: Adolescent; Adult; Aged; Chloroquine; Drug Combinations; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine; Sulfamonomethoxine; Sulfanilamides | 1986 |
Efficacy of malaria prophylaxis in American and Swiss travelers to Kenya.
Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Kenya; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Switzerland; Travel; United States | 1987 |
Chloroquine and Fansidar prophylaxis--a reply.
Topics: Chloroquine; Drug Combinations; Erythrocytes; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1987 |
Plasma and whole blood mefloquine concentrations during treatment of chloroquine-resistant falciparum malaria with the combination mefloquine-sulphadoxine-pyrimethamine.
Topics: Adolescent; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Intestinal Absorption; Kinetics; Malaria; Male; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides | 1987 |
Excretion of chloroquine, dapsone and pyrimethamine in human milk.
Topics: Adult; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Milk, Human; Pregnancy; Pyrimethamine | 1986 |
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Erythrocyte Count; Female; Humans; Leukocyte Count; Leukopenia; Liver Function Tests; Malaria; Male; Middle Aged; Pyrimethamine; Switzerland; Travel | 1987 |
Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine.
Topics: Child, Preschool; Chloroquine; Drug Combinations; Humans; Malaria; Male; Pyrimethamine; Stevens-Johnson Syndrome; Sulfadoxine; Sulfanilamides | 1986 |
Malaria prophylaxis.
Topics: Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine | 1986 |
Experiences with malaria chemoprophylaxis.
Topics: Adult; Chloroquine; Humans; Hungary; Malaria; Pyrimethamine; Travel | 1986 |
[Experience with the therapy of symptomatic liver porphyria using a combination of antimalarial agents--chloroquine with pyrimethamine].
Topics: Adult; Aged; Chloroquine; Drug Therapy, Combination; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Pyrimethamine | 1987 |
Fatal Stevens-Johnson syndrome associated with Fansidar and chloroquine.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Therapy, Combination; Humans; Pyrimethamine; Stevens-Johnson Syndrome; Sulfadoxine; Sulfanilamides | 1987 |
Leads from the MMWR. Adverse reactions to Fansidar and updated recommendations for its use in the prevention of malaria.
Topics: Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Travel | 1985 |
[A case of malaria tropicameningoencephalitis (neuromalaria) with chloroquine and pyrimethamine/sulfadoxine resistance].
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Mefloquine; Meningoencephalitis; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine; Sulfanilamides | 1985 |
Sensitivity of Plasmodium falciparum to antimalarial drugs in Colombia.
Topics: Amodiaquine; Antimalarials; Chloroquine; Colombia; Drug Combinations; Drug Resistance, Microbial; Geography; Humans; Malaria; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinolines; Sulfadoxine | 1985 |
Instability of resistance of Plasmodium falciparum to chloroquine and pyrimethamine in vitro.
Topics: Animals; Chloroquine; Drug Resistance; Plasmodium falciparum; Pyrimethamine | 1985 |
Chloroquine-resistant falciparum malaria in northern Malawi.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Malawi; Male; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1985 |
Susceptibility of Thai isolates of Plasmodium falciparum to artemisinine (qinghaosu) and artemether.
Topics: Animals; Artemether; Artemisinins; Chloroquine; Drug Combinations; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Thailand | 1985 |
[The combined use of artemether, sulfadoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant falciparum malaria].
Topics: Adult; Animals; Antimalarials; Artemether; Artemisinins; Child; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 1985 |
Malaria prophylaxis for Canadian travellers.
Topics: Amodiaquine; Canada; Chloroquine; Dapsone; Doxycycline; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Infant; Infant, Newborn; Malaria; Plasmodium; Plasmodium falciparum; Pregnancy; Premedication; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1985 |
[Studies on the chemoresistance of Plasmodium falciparum in Africa: current data].
Topics: Africa; Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Mefloquine; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinolines | 1985 |
In vivo assessment of the sensitivity of Plasmodium falciparum to sulphadoxine/pyrimethamine combination (Fansidar) in six localities in Tanzania where chloroquine-resistant P. falciparum has been detected.
Topics: Adolescent; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Follow-Up Studies; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Tanzania | 1985 |
Susceptibility of Plasmodium falciparum in The Gambia to pyrimethamine, Maloprim and chloroquine.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; Gambia; Humans; Infant; Malaria; Male; Microbial Sensitivity Tests; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine | 1985 |
Drug-resistant malaria--changing patterns mean difficult decisions.
Topics: Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance, Microbial; Humans; Infant; Kenya; Malaria; Microbial Sensitivity Tests; Plasmodium; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sulfadoxine | 1985 |
[Malaria chemoprophylaxis. Resistance problems].
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Infant; Malaria; Mefloquine; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Quinolines; Sulfadoxine | 1985 |
Adverse reactions to Fansidar and updated recommendations for its use in the prevention of malaria.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Travel | 1985 |
Fansidar in malaria prophylaxis.
Topics: Antimalarials; Chloroquine; Drug Combinations; Humans; Malaria; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1985 |
Pre-exposure rabies immunization with human diploid cell vaccine: decreased antibody responses in persons immunized in developing countries.
Topics: Adult; Antibodies, Viral; Chloroquine; Developing Countries; Drug Combinations; Female; Humans; Immune Tolerance; Immunization; Kenya; Pyrimethamine; Rabies; Rabies Vaccines; Rabies virus; Sulfadoxine; United States | 1985 |
[Malaria in 1985: new recommendations].
Topics: Africa; Asia; Chloroquine; Drug Combinations; Humans; Malaria; Pyrimethamine; South America; Sulfadoxine; Sulfanilamides | 1985 |
A comparison of chloroquine and pyrimethamine as malaria chemoprophylactics in young Nigerian children.
Topics: Antibodies; Chloroquine; Enzyme-Linked Immunosorbent Assay; Ferritins; Folic Acid; Hemodynamics; Humans; Infant; Malaria; Pyrimethamine; Vomiting | 1985 |
[Remarks on the drug prevention of malaria].
Topics: Adult; Antimalarials; Child; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance; Female; Humans; Malaria; Plasmodium; Pregnancy; Pregnancy Complications; Pyrimethamine; Sulfadoxine; Travel | 1985 |
Immunity, transferrin, and survival in kwashiorkor.
Topics: Child, Preschool; Chloroquine; Diet Therapy; Dietary Proteins; Female; Folic Acid; gamma-Globulins; Humans; Immunoglobulins; Infant; Infections; Iron; Kwashiorkor; Male; Pyrimethamine; Serum Albumin; Transferrin; Uric Acid; Vitamins | 1970 |
Letter: Antimalarial drugs and Burkitt's lymphoma.
Topics: Adult; Africa; Animals; Burkitt Lymphoma; Carcinogens; Child; Chloroquine; Humans; Plant Extracts; Plants; Pyrimethamine; Rats; Tropical Medicine | 1974 |
Choroquine-resistant Plasmodium falciparum malaria in the United Kingdom.
Topics: Adult; Chloroquine; England; Humans; Malaria; Malaysia; Male; Penicillin Resistance; Penicillins; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Sulfonamides | 1968 |
Drug-resistant malaria.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfonamides | 1969 |
Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine.
Topics: Chloroquine; Dapsone; Formaldehyde; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine | 1973 |
Malaria studies in vitro. II. The measurement of drug activities using leucocyte-free blood-dilution cultures of Plasmodium berghei and 3H-leucine.
Topics: Adenosine Triphosphate; Animals; Antimalarials; Blood; Cells, Cultured; Chloroquine; Cricetinae; Erythrocytes; Haplorhini; Leucine; Leukocyte Count; Leukocytes; Metabolism; Mice; Plasmodium; Plasmodium berghei; Pyrimethamine; Rats; Reticulocytes | 1973 |
Experience with mixed infections of Plasmodium falciparum and vivax.
Topics: Antimalarials; Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Sulfisoxazole; United States; Vietnam | 1973 |
Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama.
Topics: Adult; Amodiaquine; Animals; Anopheles; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Haplorhini; Humans; Malaria; Male; Panama; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Recurrence; Sulfadiazine | 1974 |
Infections with Plasmodium falciparum and Plasmodium vivax in the owl monkey--model systems for basic biological and chemotherapeutic studies.
Topics: Animal Feed; Animals; Butylamines; Chlorobenzenes; Chloroquine; Colombia; Darkness; Disease Models, Animal; Drug Resistance, Microbial; Haplorhini; Humans; Injections, Intravenous; Malaria; Methanol; Methods; Piperidines; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quarantine; Quinine; Quinolines; Splenectomy | 1973 |
Resistance to antimalarials.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Pyrimethamine | 1966 |
Coombs'-positive hemolytic disease in malaria.
Topics: Adrenal Cortex Hormones; Adult; Anemia, Hemolytic; Antibodies; Chloroquine; Coombs Test; Drug Eruptions; Drug Resistance, Microbial; Erythrocytes; Hematocrit; Humans; Malaria; Male; Pyrimethamine; Quinine; Sulfadiazine | 1968 |
The control of malaria among the Orang Asli in West Malaysia.
Topics: Adolescent; Adult; Aged; Asian People; Black People; Child; Child, Preschool; Chloroquine; Ethnicity; Female; Humans; Infant; Malaria; Malaysia; Male; Methods; Middle Aged; Mosquito Control; Pyrimethamine | 1972 |
Characterization of a drug resistant strain of Plasmodium falciparum from Burma.
Topics: Adult; Amodiaquine; Anopheles; Chloroquine; Drug Resistance, Microbial; Human Experimentation; Humans; Insect Vectors; Malaria; Male; Myanmar; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine | 1973 |
Generalised pustular drug rash.
Topics: Adult; Aged; Biguanides; Chloramphenicol; Chloroquine; Cross Reactions; Digoxin; Drug Eruptions; Furosemide; Heart Failure; Humans; Malaria; Male; Mastoiditis; Middle Aged; Piperazines; Pruritus Ani; Pyrimethamine; Skin Manifestations | 1973 |
Treatment of uveitis with methotrexate.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Alopecia; Anti-Bacterial Agents; Child; Chloroquine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Middle Aged; Nausea; Ophthalmia, Sympathetic; Pyrimethamine; Stomatitis; Uveitis; Vision, Ocular; Vomiting | 1969 |
Forty years of malaria control in Natal and Zululand.
Topics: Animals; Anopheles; Chloroquine; DDT; Disease Outbreaks; Emigration and Immigration; Health Education; Housing; Humans; Insect Vectors; Malaria; Mosquito Control; Mozambique; Pyrimethamine; South Africa | 1974 |
Malaria prophylactic drug trial in Western Nigeria.
Topics: Child; Chloroquine; Drug Evaluation; Humans; Malaria; Nigeria; Pyrimethamine | 1974 |
[Prevention of malaria].
Topics: Antimalarials; Chloroquine; Humans; Malaria; Proguanil; Pyrimethamine; World Health Organization | 1974 |
Effect of four different types of single-dose treatment with chloroquine and with chloroquine and pyrimethamine on Plasmodium falciparum infections in a semi-immune population in northern Nigeria.
Topics: Adolescent; Child; Child, Preschool; Chloroquine; Drug Combinations; Humans; Infant; Malaria; Nigeria; Plasmodium falciparum; Pyrimethamine | 1972 |
Response of drug-resistant Plasmodium falciparum to combined therapy in Panama.
Topics: Adult; Amodiaquine; Child; Chloroquine; Drug Resistance, Microbial; Humans; Infant; Malaria; Panama; Plasmodium falciparum; Primaquine; Pyrimethamine; Sulfadimethoxine; Sulfonamides | 1972 |
Sulphadoxine and pyrimethamine as treatment for acute Plasmodium falciparum malaria.
Topics: Acute Disease; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Sulfonamides | 1972 |
A model in vitro system to test the susceptibility of human malarial parasites to antimalarial drugs.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Trimethoprim | 1972 |
Experience with mass drug administration as a supplementary attack measure in areas of vivax malaria.
Topics: Anopheles; Chloroquine; DDT; Emergencies; Humans; Insecticide Resistance; Malaria; Mosquito Control; Plasmodium vivax; Pyrimethamine; Syria | 1972 |
Some haematological and biochemical effects of a malaria control programme in New Guinea.
Topics: Adolescent; Adult; Antimalarials; Blood Group Antigens; Blood Proteins; Child; Child, Preschool; Chloroquine; DDT; Dieldrin; Electrophoresis, Starch Gel; Female; Haptoglobins; Hemoglobins; Humans; Infant; Infant, Newborn; Insecticides; Iron; Malaria; Male; New Guinea; Plasmodium malariae; Pyrimethamine; Splenomegaly; Transferrin | 1973 |
The chemotherapy of rodent malaria. XVII. Dynamics of drug resistance. 3. Influence of drug combinations on the development of resistance to chloroquine in P. berghei.
Topics: Animals; Chloroquine; Drug Interactions; Drug Resistance, Microbial; Malaria; Mice; Plasmodium berghei; Pyrimethamine; Sulfadiazine; Sulfaphenazole; Sulfonamides | 1973 |
Characterisation of a drug resistant strain of Plasmodium falciparum from Sabah.
Topics: Adult; Amodiaquine; Borneo; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine | 1973 |
The suppression of Plasmodium falciparum and Plasmodium vivax parasitaemias by a dapsone-pyrimethamine combination.
Topics: Adolescent; Adult; Child; Chloroquine; Dapsone; Drug Combinations; Female; Hematocrit; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Thailand | 1973 |
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Leukopenia; Liver Diseases; Liver Function Tests; Malaria; Male; Military Medicine; Plasmodium falciparum; Proteinuria; Pulmonary Edema; Pyrimethamine; Quinine; Thrombocytopenia; Vietnam | 1973 |
The evaluation of the presumptive and radical treatments against falciparum malaria in Thailand.
Topics: Adolescent; Adult; Blood; Chloroquine; Drug Evaluation; Female; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Recurrence; Sulfadimethoxine; Thailand | 1973 |
Malaria in New York City. IV. 1960-1971.
Topics: Adolescent; Adult; Africa, Western; Age Factors; Amodiaquine; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; New York City; Occupations; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Seasons; Sex Factors; Vietnam | 1974 |
Characteristics of Plasmodium falciparum from the Solomon Islands.
Topics: Anopheles; Blood; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Pacific Islands; Plasmodium falciparum; Pyrimethamine; Quinine | 1974 |
Multidrug-resistant strain of Plasmodium falciparum from eastern Colombia.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Colombia; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine | 1974 |
Chemotherapeutic activity of combination doses of chloroquine, pyrimethamine, and sulfamethoxy-diazine, a long-acting sulfanilamide, against Plasmodium berghei infections in mice.
Topics: Animals; Chloroquine; Drug Combinations; Malaria; Mice; Plasmodium berghei; Pyrimethamine; Sulfanilamides; Time Factors | 1973 |
A comparison between the quinine and chloroquine regimens for falciparum malaria in Vietnam.
Topics: Administration, Oral; Chloroquine; Dapsone; Humans; Injections, Intravenous; Malaria; Male; Military Medicine; Naval Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfisoxazole; United States; Vietnam | 1974 |
Chemotherapy of rodent malaria: transfer of resistance vs mutation.
Topics: Animals; Blood; Cell Division; Chloroquine; Cricetinae; Drug Resistance, Microbial; Erythrocytes; Extrachromosomal Inheritance; Female; Malaria; Male; Mice; Mutation; Plasmodium; Plasmodium berghei; Pyrimethamine; Tetrahydrofolate Dehydrogenase | 1974 |
Some pharmacological aspects of antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfonamides; Trimethoprim | 1974 |
[Cerebral tropical malaria with blackwater fever. A current diagnostic and therapeutic problem].
Topics: Acute Kidney Injury; Adult; Blackwater Fever; Brain Diseases; Chloroquine; Disseminated Intravascular Coagulation; Exchange Transfusion, Whole Blood; Heparin; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine | 1974 |
[Treatment of drug-resistant malaria: animal experiments].
Topics: Amodiaquine; Animals; Chloroquine; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Folic Acid Antagonists; Leucomycins; Malaria; Mice; Plasmodium berghei; Pyrimethamine; Quinine; Quinolines; Time Factors | 1974 |
Recrudescence, poor response or resistance to quinine of falciparum malaria in Thailand.
Topics: Administration, Oral; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Injections, Intravenous; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadoxine; Thailand | 1974 |
[Malaria prevention for Swedish tourists in West-Africa].
Topics: Africa, Western; Antimalarials; Biguanides; Chloroquine; Drug Resistance; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sweden; Travel | 1974 |
Prevention of drug resistance in rodent malaria by the use of drug mixtures.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Malaria; Mice; Microbial Sensitivity Tests; Plasmodium berghei; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1974 |
Studies on the characterization of plasmodium vivax strains from Central America.
Topics: Animals; Central America; Chloroquine; Haplorhini; Humans; Lincomycin; Malaria; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine; Recurrence; Time Factors | 1972 |
Maternal anaemia and fetal birthweight.
Topics: Anemia; Anemia, Sickle Cell; Birth Weight; Blood Transfusion; Body Height; Chloroquine; Embryonic and Fetal Development; Female; Fetal Death; Folic Acid; Folic Acid Deficiency; Gestational Age; Hematocrit; Hemoglobinopathies; Humans; Malaria; Pregnancy; Pregnancy Complications; Pyrimethamine; Socioeconomic Factors | 1973 |
Letter: Delayed attacks of malaria in visitors to the tropics.
Topics: Chloroquine; Humans; Malaria; Pyrimethamine; Time Factors; Travel; Tropical Climate | 1973 |
Chronic intestinal coccidiosis in man: intestinal morphology and response to treatment.
Topics: Antiprotozoal Agents; Biopsy; Chloroquine; Chronic Disease; Coccidiosis; Diagnosis, Differential; Diarrhea; Diet Therapy; Drug Therapy, Combination; Duodenum; Follow-Up Studies; Humans; Intestinal Diseases, Parasitic; Intestine, Small; Isospora; Jejunum; Malabsorption Syndromes; Male; Metronidazole; Microscopy, Electron; Middle Aged; Nitrofurantoin; Primaquine; Pyrimethamine; Quinacrine; Sulfadiazine; Tetracycline; Time Factors | 1974 |
Effects of pyrimethamine, chlorguanide, and primaquine against exoerythrocytic forms of a strain of chloroquine-resistant Plasmodium falciparum from Thailand.
Topics: Adult; Chloroquine; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Thailand | 1967 |
Treatment of acute falciparum malaria with sulfalene and trimethoprim.
Topics: Chloroquine; Folic Acid Antagonists; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfonamides | 1968 |
[Resistance in Protozoa].
Topics: Antiprotozoal Agents; Chloroquine; Drug Synergism; Malaria; Plasmodium; Pyrimethamine; Trypanosoma | 1967 |
Antimalarial effects of sulphormethoxine, diaphenylsulphone and separate combinations of these with pyrimethamine: a review of preliminary investigations carried out in Tanzania.
Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Dapsone; Drug Hypersensitivity; Drug Resistance, Microbial; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Sulfonamides; Tanzania | 1968 |
[Treatment of "P. falciparum" malaria by delayed-action sulfonamides].
Topics: Antimalarials; Chloroquine; Delayed-Action Preparations; Drug Synergism; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadimethoxine | 1967 |
Apparent chloroquine-resistant falciparum malaria from coastal Brazil.
Topics: Brazil; Chloroquine; Drug Resistance, Microbial; Geography; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadiazine | 1968 |
Early experiences in the treatment of falciparum malaria from Southeast Asia.
Topics: Asia, Southeastern; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Plasmodium malariae; Pyrimethamine; Quinine | 1968 |
The sporogonous of Plasmodium vivax in Anopheles mosquitoes as a system for evaluating the prophylactic and curative capabilities of potential antimalarial compounds.
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Malaria; Naphthoquinones; Oxytetracycline; Penicillin G; Plasmodium vivax; Primaquine; Proguanil; Pyridines; Pyrimethamine; Quinacrine; Quinine; Quinolines; Sulfadiazine; Thiosemicarbazones | 1968 |
Chloroquine-pyrimethamine-sulfisoxazole therapy of Plasmodium falciparum malaria. An alternative to quinine.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Fever; Humans; Malaria; Male; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfisoxazole; Vietnam | 1969 |
Studies on the relationship between fluorescent antibody response and ecology of malaria in Malaysia.
Topics: Adolescent; Adult; Anopheles; Child; Child, Preschool; Chloroquine; Ecology; Fluorescent Antibody Technique; Humans; Malaria; Malaysia; Plasmodium; Pyrimethamine | 1968 |
A clinical view of the biology of Plasmodia.
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine | 1969 |
Acute falciparum malaria. Field experience with quinine-pyrimethamine combined therapy.
Topics: Chloroquine; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Vietnam | 1969 |
Response to drugs of South American strains of Plasmodium falciparum.
Topics: Chloroquine; Drug Resistance, Microbial; Drug Synergism; Fever; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; South America; Sulfadiazine; Sulfadimethoxine; Sulfamethoxypyridazine; Sulfonamides | 1968 |
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques; Drug Resistance, Microbial; Fever; Humans; Iron; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Scrub Typhus; Sulfadiazine; Thrombocytopenia; Vietnam | 1969 |
Antimalarial activity of Kelfizina-trimethoprim and Kelfizina-pyrimethamine versus chloroquine in field trials in Nigeria.
Topics: Adolescent; Adult; Child; Child, Preschool; Chloroquine; Folic Acid Antagonists; Humans; Infant; Malaria; Middle Aged; Nigeria; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Sulfonamides | 1969 |
Combination therapy of malaria.
Topics: Chloroquine; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfisoxazole | 1969 |
Fatal transfusion malaria.
Topics: Blood Volume; Chloroquine; Chorea; Dehydration; Dexamethasone; Humans; Malaria; Male; Middle Aged; Neurologic Manifestations; Plasmodium falciparum; Pulmonary Edema; Pyrimethamine; Quinine; Transfusion Reaction | 1969 |
Fatal pulmonary edema as a complication of acute falciparum malaria.
Topics: Adolescent; Adult; Cephalosporins; Chloroquine; Digitalis Glycosides; Humans; Hypersensitivity; Malaria; Male; Meperidine; Morphine; Penicillins; Plasmodium falciparum; Pulmonary Edema; Pyrimethamine; Quinine; Radiography; Sulfisoxazole; Vietnam | 1970 |
Response of Laotian malaria strains to chemotherapy.
Topics: Adult; Antimalarials; Asian People; Chloroquine; Drug Resistance, Microbial; Humans; Japan; Laos; Malaria; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfamethoxypyridazine; Sulfonamides; Thailand; Time Factors | 1970 |
Experience with an insecticide-drug combination and observations on suppressive chloroquine-pyrimethamine treatment.
Topics: Child; Chloroquine; DDT; Humans; Malaria; Malaysia; Mosquito Control; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Thailand | 1971 |
Malaria at Nam Ngum Dam construction site in Laos. I. Suppression with combinations of sulfonamides and pyrimethamine.
Topics: Chloroquine; Female; Humans; Laos; Leukopenia; Malaria; Male; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pyrimethamine; Sulfonamides | 1971 |
Malaria revisited.
Topics: Chloroquine; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Sulfonamides; United States; Vietnam | 1971 |
Curative and suppressive treatment of P. falciparum malaria with oral and parenteral Fansidar.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Synergism; Female; Humans; Infant; Injections, Intramuscular; Malaria; Mozambique; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Quinine; Sulfadoxine; Sulfonamides | 1971 |
Malaria resistant to chloroquine and sulphamethoxine-pyrimethamine.
Topics: Adult; Aniline Compounds; Chloroquine; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Pyrimidines | 1971 |
Malaria suppression and prophylaxis on a Malaysian rubber estate: sulformethoxine-pyrimethamine single monthly dose vs chloroquine single weekly dose.
Topics: Adolescent; Adult; Aged; Blood; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria; Malaysia; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyridines; Pyrimethamine; Sulfonamides | 1971 |
Acquired decrease in sensitivity to quinine observed during studies with a strain of chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadiazine; Time Factors | 1967 |
Clinical experience with sulphadiazine and pyrimethamine in the treatment of persons experimentally infected with chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Antimalarials; Body Temperature; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Rectum; Recurrence; Sulfadiazine | 1967 |
[Chemotherapeutic activity of standard antimalarials in a simplified test for Plasmodium vinckey infection in the NMPI mouse].
Topics: Animals; Antimalarials; Chloroquine; Long-Term Care; Malaria; Mice; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Sulfonamides; Time Factors | 1970 |
Action of some antimalaria compounds against Plasmodium berghei in vitro.
Topics: Animals; Antimalarials; Chloroquine; Haplorhini; Leucine; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinine; Triazines; Tritium | 1971 |
[Causal preventive activity of standard antimalarials in rodent malaria (Plasmodium berghei yoelii)].
Topics: Animals; Anopheles; Antimalarials; Chloroquine; Malaria; Mice; Mice, Inbred Strains; Plasmodium; Primaquine; Pyrimethamine; Quinine; Rodent Diseases; Sulfadiazine | 1972 |
The role of drugs in a malaria program.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Malaria; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Recurrence; Sulfonamides; Sulfones; Trimethoprim | 1972 |
The chemotherapy of rodent malaria. XIV. The action of some sulphonamides alone or with folic reductase inhibitors against malaria vectors and parasites. 4. The response of normal and drug-resistant strains of Plasmodium berghei.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Folic Acid Antagonists; Malaria; Male; Mice; Primaquine; Proguanil; Pyrimethamine; Pyrimidines; Sulfadimethoxine; Sulfonamides | 1971 |
Malaria in childhood.
Topics: Child, Preschool; Chloroquine; Female; Humans; Infant; Malaria; Male; Nigeria; Pyrimethamine | 1971 |
[Effectiveness of trypanocides berenil and pentamidine in rodent malaria (Plasmodium vinckei)].
Topics: Acetates; Amidines; Animals; Antimalarials; Azo Compounds; Chloroquine; Cresols; Glycine; Malaria; Pyrimethamine; Rodent Diseases | 1971 |
Heterophile antibodies, M-antiglobulins, immunoglobulins and acute phase proteins in pregnancy in Nigeria.
Topics: Antibodies; Antibodies, Anti-Idiotypic; C-Reactive Protein; Ceruloplasmin; Chloroquine; Female; Humans; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Malaria; Nigeria; Pregnancy; Pyrimethamine; Serum Albumin; Transferrin | 1970 |
Management of chloroquine resistant falciparum malaria.
Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Humans; Malaria; Male; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Tropical Medicine; United States; Vietnam | 1967 |
Plasmodium vinckei: production of chloroquine-resistant strain.
Topics: Animals; Antimalarials; Arsenicals; Chloroquine; Cytoplasm; Drug Resistance, Microbial; Malaria; Methods; Mice; Mycoplasma; Pigments, Biological; Plasmodium; Primaquine; Pyrimethamine; Time Factors | 1969 |
An automated method of mass drug testing applied to screening for antimalarial activity.
Topics: Animals; Antimalarials; Automation; Chloroquine; Erythrocytes; Glucose; Glycolysis; Lactates; Male; Methods; Neoplasms, Experimental; Pharmacology; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rats; Sulfadiazine; Sulfones | 1970 |
A unique antinucleic acid approach to the mass screening of antimalarial drugs.
Topics: Animals; Antimalarials; Cell Membrane; Chemical Phenomena; Chemistry; Chloroquine; Computers; DNA, Bacterial; Erythrocytes; Hydrogen-Ion Concentration; Nucleosides; Pharmacology; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rats; RNA, Bacterial; Sulfones; Temperature; Tritium | 1970 |
The chemotherapy of rodent malaria. IX. Causal prophylaxis. I. A method for demonstrating drug action on exo-erythrocytic stages.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Malaria; Male; Mice; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Triazines | 1970 |
The chemotherapy of rodent malaria. XII. Substituted tetrahydrofurans, a new chemical family of antimalarials. The action of 2-(p-chlorophenyl)-2-(4-piperidyl)-tetrahydrofuran against Plasmodium berghei and Plasmodium chabaudi.
Topics: Aminobenzoates; Animals; Antimalarials; Chloroquine; Diet; Drug Resistance, Microbial; Drug Synergism; Folic Acid; Furans; Mice; Piperidines; Plasmodium; Pyrimethamine; Quinacrine; Sulfadiazine; Triazines | 1970 |
Plasmodium fallax and P. gallinaceum: experimental resistance to primaquine.
Topics: Animals; Biological Assay; Chick Embryo; Chickens; Chloroquine; Cross Reactions; Drug Resistance, Microbial; Insect Vectors; Plasmodium; Primaquine; Pyrimethamine; Species Specificity; Time Factors; Turkeys | 1970 |
Methaemoglobin levels in soldiers receiving antimalarial drugs.
Topics: Antimalarials; Australia; Chloroquine; Dapsone; Erythrocyte Count; Humans; Methemoglobin; Military Personnel; Primaquine; Pyrimethamine; Quinine; Reticulocytes; Vietnam | 1971 |
[Treatment of chronic acquired toxoplasmosis].
Topics: Ascorbic Acid; Chloroquine; Chronic Disease; Humans; Prednisolone; Promethazine; Pyrimethamine; Sulfamethazine; Toxoplasmosis; Vitamins | 1971 |
Malaria chemoprophylaxis.
Topics: Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Emigration and Immigration; Female; Humans; Malaria; Pregnancy; Pyrimethamine; Quinolines | 1971 |
Barrier spraying at the Kelantan side of the Thai-Malaysia border.
Topics: Anopheles; Child; Chloroquine; DDT; Dieldrin; Housing; Humans; Insect Vectors; Insecticide Resistance; Malaria; Malaysia; Mosquito Control; Pyrimethamine; Seasons; Thailand | 1971 |
[Prophylaxis versus suppression of malaria].
Topics: Chloroquine; Humans; Malaria; Proguanil; Pyrimethamine | 1967 |
[Observation of a South American skin leishmaniasis in Germany].
Topics: Adult; Antiprotozoal Agents; Berlin; Chloroquine; Humans; Leishmaniasis, Mucocutaneous; Male; Pyrimethamine | 1967 |
[Further development of the Roehl test for testing antimalarial agents on Plasmodium cathemerium in the canary by intravenous administration].
Topics: Animals; Animals, Laboratory; Antimalarials; Canaries; Chloroquine; Injections, Intravenous; Malaria, Avian; Methods; Primaquine; Proguanil; Pyrimethamine; Quinine; Sulfadiazine; Sulfanilamides; Sulfonamides | 1967 |
Chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Humans; Malaria; Military Medicine; Pyrimethamine; Quinine; Vietnam | 1967 |
Survival time and retention of antimalarial resistance of malarial parasites in repository in liquid nitrogen (--196 C).
Topics: Antimalarials; Chloroquine; Drug Resistance, Microbial; Freezing; Plasmodium; Preservation, Biological; Pyrimethamine | 1968 |
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hematocrit; Isoenzymes; L-Lactate Dehydrogenase; Malaria; Mice; Organ Size; Plasmodium; Primaquine; Pyrimethamine; Quinacrine; Quinine; Rodent Diseases; Serum Albumin; Serum Globulins; Spleen; Splenomegaly; Sulfadiazine | 1968 |
Malaria--the British point of view.
Topics: Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Malaysia; Military Medicine; Proguanil; Pyrimethamine; Sulfadimethoxine; United Kingdom | 1969 |
Comparative response of various rodent malarias to chemotherapy.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Malaria; Male; Mice; Pyrimethamine | 1969 |
Cerebral malaria following blood transfusion.
Topics: Adult; Brain Diseases; Chloroquine; Communicable Disease Control; Disease Reservoirs; Humans; Malaria; Male; Pyrimethamine; Transfusion Reaction | 1969 |
Selection of strains of Plasmodium berghei resistant to quinine, chloroquine, and pyrimethamine.
Topics: Animals; Chloroquine; Mice; Pigmentation; Plasmodium; Pyrimethamine; Quinine | 1965 |
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. I. Chloroquine resistance.
Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Malaria; Mice; Plasmodium; Primaquine; Proguanil; Pyrimethamine; Quinacrine; Sulfadiazine; Triazines | 1965 |
Daraclor trial.
Topics: Child; Child, Preschool; Chloroquine; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Pyrimethamine | 1966 |
Leishmaniasis in the Sudan Republic. 27. Lack of effect of chloroquine and pyrimethamine on visceral leishmaniasis in the hamster.
Topics: Animals; Chloroquine; Cricetinae; Leishmaniasis; Liver; Pyrimethamine; Sudan | 1966 |
Drug responses of mepacrine- and primaquine-resistant strains of Plasmodium berghei Vincke and Lips, 1948.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Mice; Plasmodium; Primaquine; Pyrimethamine; Quinine; Sulfadiazine | 1966 |
A study of resistance to cycloguanil in Plasmodium gallinaceum in chicks.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Malaria, Avian; Plasmodium; Pyrimethamine | 1966 |
Treatment of chloroquine-resistant Plasmodium falciparum infections in Vietnam.
Topics: Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinacrine; Quinine; Sulfadiazine; Sulfonamides; Vietnam | 1967 |
The different effects of antimalarial drugs on Plasmodium lophurae developing intracellularly and extracellularly in vitro.
Topics: Animals; Chloroquine; In Vitro Techniques; Malaria, Avian; Plasmodium; Pyrimethamine; Quinacrine; Sulfadiazine | 1967 |
Hückel molecular orbital calculations for some antimalarial drugs and related molecules.
Topics: Antimalarials; Chemical Phenomena; Chemistry, Physical; Chloroquine; DNA; Primaquine; Pyrimethamine; Quinacrine; Quinine; RNA | 1967 |
Chemotherapy of sporozoite- and blood-induced Plasmodium berghei infections with selected antimalarial agents.
Topics: Animals; Chloroquine; Cricetinae; Dapsone; Malaria; Mice; Primaquine; Pyrimethamine; Quinine; Rats | 1967 |
Tolerance and haematological findings with antimalarials (chloroquine and Fansidar [pyrimethamine plus sulfadoxine]) in adults and children during field trials in Nigeria.
Topics: Adult; Child; Chloroquine; Drug Combinations; Drug Tolerance; Female; Hemoglobinometry; Humans; Leukocyte Count; Malaria; Male; Nigeria; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1980 |
Single dose therapy with a combination of chloroquine and pyrimethamine (darachlor) in the treatment of malaria. Short communication.
Topics: Administration, Oral; Adult; Child, Preschool; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Tablets | 1981 |
Chemoprophylaxis of malaria in non-immune residents in Dar es Salaam, Tanzania.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Middle Aged; Patient Compliance; Plasmodium falciparum; Proguanil; Pyrimethamine; Retrospective Studies; Sulfadoxine; Tanzania | 1984 |
A rabbit--in vitro system to evaluate drug action against Plasmodium falciparum.
Topics: Acedapsone; Animals; Antimalarials; Chloroquine; Drug Evaluation, Preclinical; Male; Mefloquine; Microbial Sensitivity Tests; Models, Biological; Plasmodium falciparum; Pyrimethamine; Quinolines; Rabbits; Time Factors; Triazines | 1983 |
The effect of anti-malarial drugs on human natural killer cells in vitro.
Topics: Antimalarials; Cell Line; Chloroquine; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Leukemia, Myeloid, Acute; Mefloquine; Primaquine; Pyrimethamine; Quinacrine; Quinine; Quinolines | 1984 |
Toxicity and side-effects of antimalarials in Africa: a critical review.
Topics: Africa; Aminoquinolines; Antimalarials; Cardiovascular Diseases; Chloroquine; Dapsone; Eye Diseases; Humans; Labyrinth Diseases; Movement Disorders; Neuromuscular Diseases; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
[Falciparum malaria in East African tourists in spite of fansidar prevention. A contribution on increased chloroquine and pyrimethamine-sulfadoxine resistance in areas of East Africa].
Topics: Adult; Africa, Eastern; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Erythrocytes; Female; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1983 |
[Drug-resistant malaria in East Africa].
Topics: Adult; Africa, Eastern; Aged; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1983 |
Combined chloroquine/Fansidar-resistant falciparum malaria appears in East Africa.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Tanzania | 1983 |
Treatment of chloroquine-resistant malaria during pregnancy.
Topics: Adult; Chloroquine; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine; Sulfameter; Sulfanilamides | 1983 |
A simple field kit for the determination of drug susceptibility in Plasmodium falciparum.
Topics: Chloroquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Reagent Kits, Diagnostic | 1983 |
Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines; Thailand | 1983 |
[Chloroquine- and fansidar-resistant falciparum malaria treated with minocycline].
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Minocycline; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides; Tetracyclines | 1983 |
Drug sensitivity and isoenzyme type in cloned lines of Plasmodium falciparum.
Topics: Africa; Animals; Brazil; Chloroquine; Clone Cells; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Glucose-6-Phosphate Isomerase; Isoenzymes; Plasmodium falciparum; Pyrimethamine | 1984 |
Chloroquine-resistant falciparum malaria from Malawi.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Malawi; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1984 |
[Chloroquine and pyrimethamine/sulfadoxine resistant malaria tropica in a child with diabetes mellitus].
Topics: Adolescent; Chloroquine; Diabetes Mellitus, Type 1; Diagnosis, Differential; Doxycycline; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides | 1984 |
Probable chloroquine-resistant Plasmodium falciparum malaria in south-western Africa.
Topics: Adult; Africa, Southern; Africa, Western; Animals; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Tetracycline | 1984 |
Concomitant resistance to pyrimethamine and cycloguanil of chloroquine-resistant falciparum malaria from East Africa: an in vitro study of 12 isolates.
Topics: Africa, Eastern; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Microbial Sensitivity Tests; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 1984 |
Gametocyte-forming and non-gametocyte-forming clones of Plasmodium falciparum.
Topics: Animals; Chloroquine; Clone Cells; Drug Resistance, Microbial; Erythrocytes; Plasmodium falciparum; Primaquine; Pyrimethamine | 1984 |
The activity of proguanil and its metabolites, cycloguanil and p-chlorophenylbiguanide, against Plasmodium falciparum in vitro.
Topics: Animals; Biguanides; Chloroquine; Microbial Sensitivity Tests; Plasmodium falciparum; Proguanil; Pyrimethamine; Triazines | 1984 |
Kenyan chloroquin, fansidar and quninine resistant P. Falciparum.
Topics: Adolescent; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinidine; Sulfadoxine; Sulfanilamides | 1984 |
A new in vitro test for pyrimethamine/sulfadoxine susceptibility of Plasmodium falciparum and its correlation with in vivo resistance in Kenya.
Topics: Adolescent; Child; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Kenya; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1984 |
Malaria chemoprophylaxis--which drug?
Topics: Adult; Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sulfadoxine | 1983 |
[In vitro sensitivity tests of Plasmodium falciparum samples of the Amazonian Basin (Brazil)].
Topics: Amodiaquine; Animals; Antimalarials; Brazil; Chloroquine; In Vitro Techniques; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Quinolines | 1983 |
[Treatment of malaria. Update].
Topics: Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
Malaria in Christchurch.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; New Zealand; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Pyrimethamine | 1984 |
Malaria chemoprophylaxis for multiple drug resistant Plasmodium falciparum in Africa: an increasing problem.
Topics: Adult; Africa; Antimalarials; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Travel | 1984 |
[Plasmodium falciparum and drug resistance].
Topics: Adult; Africa, Eastern; Animals; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1984 |
[Malaria prevention with Fansidar].
Topics: Chloroquine; Double-Blind Method; Drug Combinations; Humans; Malaria; Nigeria; Plasmodium; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1983 |
Falciparum malaria resistant to chloroquine and fansidar: implications for prophylaxis.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1983 |
Malaria prophylaxis for long term visitors.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; Proguanil; Pyrimethamine; Sulfonamides; Sulfones; Time Factors; Travel | 1983 |
Falciparum malaria resistant to chloroquine and Fansidar.
Topics: Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1984 |
Falciparum malaria resistant to chloroquine and Fansidar: implications for prophylaxis.
Topics: Chloroquine; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1984 |
Management of Plasmodium falciparum malaria.
Topics: Amodiaquine; Anemia; Antimalarials; Brain Diseases; Chloroquine; Drug Resistance; Female; Humans; Hypoglycemia; Malaria; Oliguria; Pregnancy; Pregnancy Complications, Infectious; Pulmonary Edema; Pyrimethamine; Quinine; Sulfadoxine | 1984 |
Protection against Plasmodium berghei yoelii in chloroquine- and pyrimethamine-treated mice.
Topics: Animals; Chloroquine; Malaria; Mice; Plasmodium; Pyrimethamine | 1984 |
[Controlling the binding of porphyrins to ligands using antimalarial agents].
Topics: Chloroquine; Humans; Liver; Porphyrins; Protein Binding; Pyrimethamine | 1984 |
Effects of antimalarial drugs on human natural killer cell activity.
Topics: Antimalarials; B-Lymphocytes; Chloroquine; Humans; Killer Cells, Natural; Lymphocytes; Lymphocytes, Null; Malaria; Potassium; Pyrimethamine; Quinine; Sodium; T-Lymphocytes | 1983 |
Effect of antimalarial drugs on human neutrophil chemotaxis in vitro.
Topics: Antimalarials; Chemotaxis, Leukocyte; Chloroquine; Drug Combinations; Humans; Neutrophils; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Tetracycline; Triazines | 1983 |
[Embryotoxicity of chloroquine and pyrimethamine in rats].
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Bone and Bones; Chloroquine; Embryo, Mammalian; Female; Pregnancy; Pyrimethamine; Rats | 1983 |
Susceptibility of in vitro cultured Plasmodium falciparum to chloroquine and combination of sulfadoxine and pyrimethamine.
Topics: Animals; Chloroquine; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1982 |
[Treatment of malaria with a combination of 3 drugs on São Luís Island, Maranhão, Brazil].
Topics: Antimalarials; Brazil; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Time Factors | 1981 |
A case of fansidar-resistant Plasmodium falciparum from Tanzania.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1982 |
Fansidar-resistant Plasmodium falciparum infection from Tanzania.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Sulfanilamides | 1982 |
[Treatment of malaria with a combination of 3 drugs on the Island of São Luis, Maranhão, Brazil].
Topics: Antimalarials; Chloroquine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine | 1981 |
In vitro assessment of 2-acetylpyridine thiosemicarbazones against chloroquine-resistant Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Malaria; Mefloquine; Mice; Plasmodium falciparum; Pyrimethamine; Quinolines; Structure-Activity Relationship; Thiosemicarbazones | 1982 |
[Resistance of Plasmodium falciparum to fansidar, quinine and tetracycline].
Topics: Adolescent; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Microbial; Female; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Sulfanilamides; Tetracycline | 1982 |
Prevention of malaria in travelers 1982.
Topics: Child; Chloroquine; Drug Resistance, Microbial; Female; Humans; Malaria; Plasmodium; Plasmodium falciparum; Pregnancy; Pyrimethamine; Risk; Sulfadoxine; Travel | 1982 |
Plasmodium gallinaceum: avian screen for drugs with radical curative properties.
Topics: Animals; Antimalarials; Chickens; Chloroquine; Drug Evaluation, Preclinical; Malaria, Avian; Plasmodium; Primaquine; Pyrimethamine | 1983 |
Plasmodium chabaudi: genetics of resistance to chloroquine.
Topics: Animals; Chloroquine; Crosses, Genetic; Drug Resistance; Genes; Genetic Markers; Isoenzymes; L-Lactate Dehydrogenase; Plasmodium; Pyrimethamine | 1981 |
Chemoprophylaxis in malaria.
Topics: Chloroquine; Drug Resistance, Microbial; Female; Humans; Malaria; Plasmodium falciparum; Pregnancy; Proguanil; Pyrimethamine | 1980 |
The inhibitory effect of a drug combination on the development of mefloquine resistance in Plasmodium berghei.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Erythrocytes; Male; Mefloquine; Mice; Piperidines; Plasmodium berghei; Pyrimethamine; Quinolines; Sulfadoxine | 1980 |
[A case of chloroquine-resistant (R1) falciparum malaria from the East African Comoros Islands (author's transl)].
Topics: Africa, Eastern; Chloroquine; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1980 |
Malaria prophylaxis in travelers.
Topics: Africa; Antimalarials; Asia; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant, Newborn; Lactation; Malaria; Plasmodium falciparum; Pregnancy; Pyrimethamine; Risk; South America; Sulfadoxine; Travel; United States | 1980 |
Malaria in southeast Queensland in 1979.
Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant; Infant, Newborn; Malaria; Male; Middle Aged; New Guinea; Plasmodium falciparum; Plasmodium vivax; Primaquine; Pyrimethamine; Quinine; Sulfadoxine; Tinnitus; Vietnam | 1980 |
Plasmodium falciparum strains from Papua New Guinea: culture characteristics and drug sensitivity.
Topics: Adolescent; Adult; Animals; Child, Preschool; Chloroquine; Humans; Malaria; New Guinea; Plasmodium falciparum; Pyrimethamine | 1980 |
Chloroquine resistant Plasmodium falciparum infection from Lampung and South Sumatra, Indonesia.
Topics: Adult; Chloroquine; Drug Resistance; Humans; Indonesia; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1981 |
Blood schizontocidal activity of antibiotics against Plasmodium berghei sensitive as well as resistant to chloroquine, pyrimethamine and primaquine.
Topics: Animals; Anti-Bacterial Agents; Chloroquine; Drug Resistance; Malaria; Mice; Plasmodium berghei; Primaquine; Pyrimethamine | 1981 |
[Plasmodium falciparum malaria resistant to polychemotherapy. Usefulness of pathogen culture (author's transl)].
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; In Vitro Techniques; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1981 |
Resistance of ten Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests.
Topics: Animals; Chloroquine; Drug Resistance, Microbial; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Thailand | 1981 |
Sustained-release implants in the chemotherapy of experimental rodent malaria I. A comparison of the effects of some antimalarials in polydimethylsiloxane matrices.
Topics: Animals; Antimalarials; Chloroquine; Dimethylpolysiloxanes; Drug Implants; Malaria; Male; Mefloquine; Mice; Mice, Inbred Strains; Naphthoquinones; Piperidines; Plasmodium berghei; Primaquine; Proguanil; Pyrimethamine; Quinolines; Silicone Elastomers; Sulfadiazine; Triazines | 1981 |
Acute malaria in children in Madang: endemicity, clinical presentation and treatment.
Topics: Amodiaquine; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria; Papua New Guinea; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1981 |
Chloroquine-resistant Plasmodium falciparum malaria in Madang children.
Topics: Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Infant; Malaria; Male; Papua New Guinea; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1981 |
Drug-resistant malaria in Africa. A case report and review of the problem and treatment.
Topics: Adult; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Quinine; Tetracycline | 1982 |
A pyrimethamine-chloroquine combination for malaria prophylaxis during pregnancy.
Topics: Abnormalities, Drug-Induced; Chloroquine; Drug Combinations; Female; Fetus; Humans; Malaria; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine | 1982 |
Chloroquine-induced pigmentation. Case reports.
Topics: Adult; Chloroquine; Drug Combinations; Humans; Male; Pigmentation Disorders; Pyrimethamine; Skin Pigmentation | 1982 |
In vitro experiments on chloroquine and pyrimethamine absorption in the presence of antacid constituents or kaolin.
Topics: Animals; Antacids; Chloroquine; Drug Interactions; Intestinal Absorption; Kaolin; Male; Pyrimethamine; Rats; Rats, Inbred Strains | 1982 |
The management and treatment of malaria (a personal view).
Topics: Chloroquine; Female; Humans; Malaria; Male; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine | 1980 |
[Malaria chemotherapy].
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; Pyrimethamine; Sulfadoxine; Travel | 1981 |
[Contribution to the determination of four antimalarial molecules (chloroquine, quinine, pyrimethamine, sulfadoxime) mixed in biological fluids. I. Spectrophotometry UV (author's transl)].
Topics: Antimalarials; Chloroquine; Pyrimethamine; Quinine; Spectrophotometry, Ultraviolet; Sulfadoxine | 1981 |
[Observation of therapeutic effect of single-dose combined administration of Qinghaosu, sulphomethoxine, pyrimethamine and primaquine in the treatment of chloroquine-resistant malignant malaria (author's transl)].
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria; Male; Middle Aged; Primaquine; Pyrans; Pyrimethamine; Sesquiterpenes; Sulfamethazine | 1981 |
The effect of malarial chemoprophylaxis on immunoglobulin levels of pregnant Nigerian women and the newborn.
Topics: Chloroquine; Female; Fetal Blood; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Infant, Newborn; Malaria; Maternal-Fetal Exchange; Nigeria; Pregnancy; Pregnancy Complications, Infectious; Pyrimethamine | 1980 |
[Neuroendocrine syndromes with toxoplasmic origin: clinical and therapeutic considerations].
Topics: Adult; Brain Diseases; Child; Chloroquine; Female; Fenfluramine; Humans; Pyrimethamine; Sulfamethoxypyridazine; Toxoplasmosis | 1980 |
Tumour necrosis factor alpha in uncomplicated malaria in young adults.
Topics: Adolescent; Adult; Antimalarials; Case-Control Studies; Chloroquine; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Female; Humans; Malaria, Falciparum; Male; Pyrimethamine; Sex Factors; Sulfadoxine; Tumor Necrosis Factor-alpha; Zambia | 1995 |
In vitro susceptibility of Plasmodium falciparum to chloroquine, amodiaquine, quinine, mefloquine, and sulfadoxine/pyrimethamine in Equatorial Guinea.
Topics: Amodiaquine; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Equatorial Guinea; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Regression Analysis; Sulfadoxine | 1995 |
Congenital malaria in a hyperendemic area: a preliminary study.
Topics: Chloroquine; Cross-Sectional Studies; Developing Countries; Drug Administration Schedule; Female; Humans; Incidence; Infant, Newborn; Malaria, Falciparum; Male; Neonatal Screening; Nigeria; Pyrimethamine | 1993 |
Efficacy of a 3-day oral regimen of quinine in an area of northern Nigeria with low-grade resistance of Plasmodium falciparum to chloroquine and sulphadoxine-pyrimethamine.
Topics: Administration, Oral; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple; Humans; Infant; Malaria, Falciparum; Nigeria; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1995 |
Genetic changes in the population of Plasmodium falciparum in a Sudanese village over a three-year period.
Topics: Alleles; Aminohydrolases; Animals; Antigens, Protozoan; Antigens, Surface; Chloroquine; Electrophoresis, Gel, Two-Dimensional; Endopeptidases; Gene Frequency; Genes, Protozoan; Genetic Variation; Glucose-6-Phosphate Isomerase; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Plasmodium falciparum; Prevalence; Protein Precursors; Protozoan Proteins; Pyrimethamine; Seasons; Sudan | 1995 |
Sensitivity to antimalarial drugs by Plasmodium falciparum in Goundry, Oubritenga province, Burkina Faso.
Topics: Amodiaquine; Animals; Antimalarials; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; National Health Programs; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 1994 |
Malaria treatment in Vanuatu: new national treatment guidelines.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Malaria; Practice Guidelines as Topic; Pregnancy; Primaquine; Pyrimethamine; Sulfadoxine | 1994 |
Drug-resistant Plasmodium falciparum malaria in the eastern Transvaal.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
High-performance liquid chromatography determination of dapsone, monoacetyldapsone, and pyrimethamine in filter paper blood spots.
Topics: Anti-Infective Agents; Calibration; Chloroquine; Chromatography, High Pressure Liquid; Dapsone; Filtration; Humans; Indicators and Reagents; Paper; Pyrimethamine; Spectrophotometry, Ultraviolet; Sulfadoxine | 1995 |
Antimalarials during pregnancy: a cost-effectiveness analysis.
Topics: Antimalarials; Chloroquine; Cost-Benefit Analysis; Decision Support Techniques; Drug Combinations; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 1995 |
Congenitally acquired chloroquine-resistant P. falciparum malaria in an infant born in the United States.
Topics: Adult; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine; United States | 1995 |
Response of chloroquine-resistant falciparum malaria to sulfadoxine/pyrimethamine in Gokwe area of Zimbabwe.
Topics: Adult; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Monitoring; Drug Resistance; Follow-Up Studies; Humans; Malaria, Falciparum; Microbial Sensitivity Tests; Pyrimethamine; Sulfadoxine; Treatment Outcome; Zimbabwe | 1994 |
[Porphyria cutanea tarda and human immunodeficiency virus infection. Apropos of 2 further cases].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Drug Therapy, Combination; HIV Infections; Humans; Male; Porphyria Cutanea Tarda; Pyrimethamine; Substance-Related Disorders; Zidovudine | 1994 |
[In vitro sensitivity of Plasmodium falciparum to mefloquine, quinine, amodiaquine, chloroquine, pyronaridine and sulfadoxine/pyrimethamine in south Yunnan].
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Mefloquine; Naphthyridines; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1994 |
Ten-year surveillance of drug-resistant malaria in Burkina Faso (1982-1991).
Topics: Adolescent; Animals; Antimalarials; Burkina Faso; Child; Chloroquine; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Mefloquine; Plasmodium falciparum; Prevalence; Pyrimethamine; Quinine; Retrospective Studies; Sulfadoxine | 1994 |
In vitro susceptibility of Cambodian isolates of Plasmodium falciparum to halofantrine, pyronaridine and artemisinin derivatives.
Topics: Adult; Animals; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Humans; In Vitro Techniques; Mefloquine; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Triazines | 1994 |
Sensitivity of Plasmodium falciparum field-isolates from Tanzania to chloroquine, mefloquine and pyrimethamine during in vitro cultivation.
Topics: Animals; Chloroquine; Drug Resistance; Mefloquine; Parasitology; Plasmodium falciparum; Pyrimethamine; Tanzania | 1993 |
Mefloquine compared with other malaria chemoprophylactic regimens in tourists visiting east Africa.
Topics: Adult; Antimalarials; Chloroquine; Female; Humans; Kenya; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Proguanil; Pyrimethamine; Sulfadoxine; Travel | 1993 |
Chloroquine-resistant falciparum malaria in an area of rising endemicity in Zimbabwe.
Topics: Absenteeism; Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Disease Outbreaks; Drug Combinations; Drug Resistance; Follow-Up Studies; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Plasmodium falciparum; Prevalence; Pruritus; Pyrimethamine; Rural Population; Sulfadoxine; Zimbabwe | 1994 |
In vitro activity of pyrimethamine, cycloguanil, and other antimalarial drugs against African isolates and clones of Plasmodium falciparum.
Topics: Africa; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 1994 |
Sulphadoxine-pyrimethamine and chloroquine resistant Plasmodium falciparum infection in Sri Lanka.
Topics: Adult; Animals; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sri Lanka; Sulfadoxine | 1994 |
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 6. The impact of the interventions on mortality and morbidity from malaria.
Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Gambia; Humans; Hygiene; Infant; Insecticides; Malaria; Morbidity; Mosquito Control; Pyrimethamine; Rural Health; Seasons | 1993 |
Malaria prophylaxis and treatment.
Topics: Botswana; Chloroquine; Humans; Malaria; Pyrimethamine; Zimbabwe | 1993 |
[Acute respiratory failure in tropical malaria during pregnancy. Successful treatment using extracorporeal CO2 elimination].
Topics: Acute Disease; Adult; Carbon Dioxide; Cesarean Section; Chloroquine; Drug Therapy, Combination; Extracorporeal Membrane Oxygenation; Female; Humans; Lung; Malaria, Falciparum; Oxygen; Positive-Pressure Respiration; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Quinine; Respiratory Distress Syndrome; Tomography, X-Ray Computed | 1993 |
Assessment of the response in vivo and in vitro of Plasmodium falciparum to sulphadoxine-pyrimethamine in the malarious areas of Iran.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amodiaquine; Animals; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Iran; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Quinine; Regression Analysis; Sulfadoxine | 1993 |
A case of dual chloroquine and halofantrine treatment failure in Zimbabwe.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Male; Phenanthrenes; Pyrimethamine; Sulfadoxine; Zimbabwe | 1995 |
Malaria among United States troops in Somalia.
Topics: Anti-Bacterial Agents; Antimalarials; Chemoprevention; Chloroquine; Clothing; Cohort Studies; Doxycycline; Drug Resistance; Humans; Malaria, Cerebral; Malaria, Falciparum; Male; Mefloquine; Military Personnel; Population Surveillance; Prospective Studies; Protective Devices; Pyrimethamine; Quinine; Risk Factors; Somalia; Sulfadoxine; Treatment Failure; Treatment Refusal; United States | 1996 |
Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates.
Topics: Alleles; Animals; Antimalarials; Blotting, Southern; Cambodia; Chloroquine; Codon; DNA Fingerprinting; DNA, Protozoan; Drug Resistance, Multiple; Folic Acid Antagonists; Genes, Protozoan; Genetic Variation; Humans; Mefloquine; Phenanthrenes; Plasmodium falciparum; Polymorphism, Genetic; Proguanil; Pyrimethamine; Triazines | 1996 |
Evaluation of maternal practices, efficacy, and cost-effectiveness of alternative antimalarial regimens for use in pregnancy: chloroquine and sulfadoxine-pyrimethamine.
Topics: Antimalarials; Chloroquine; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Malawi; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Treatment Outcome | 1996 |
[Granulomatous hepatitis attributed to the combination pyrimethamine-chloroquine].
Topics: Antimalarials; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Chloroquine; Drug Combinations; Female; Granuloma; Humans; Middle Aged; Pyrimethamine | 1996 |
Antimalarial activity of novel arylene bis(methylketone) compounds.
Topics: Animals; Antimalarials; Chloroquine; Female; Malaria; Mice; Mice, Inbred Strains; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Pyrimidines | 1996 |
[Mechanisms and epidemiology of resistances to antimalarials].
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Molecular Epidemiology; Plasmodium falciparum; Pyrimethamine | 1996 |
Chloroquine resistance of Plasmodium falciparum malaria in Ethiopia and Eritrea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Eritrea; Ethiopia; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sulfadoxine | 1996 |
High prevalence of chloroquine resistant Plasmodium falciparum infection in Rajasthan epidemic.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Chloroquine; Disease Outbreaks; Drug Resistance, Microbial; Enzyme-Linked Immunosorbent Assay; Humans; Immunoglobulin G; Immunoglobulin M; India; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Seroepidemiologic Studies; Sulfadoxine; Tumor Necrosis Factor-alpha | 1996 |
Resurgence of malaria and drug resistance in plasmodium falciparum and plasmodium vivax species in Bombay.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Humans; Incidence; India; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Pyrimethamine; Sulfadoxine | 1995 |
Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum.
Topics: Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Genes, Protozoan; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Recombinant Proteins; Saccharomyces cerevisiae; Tetrahydrofolate Dehydrogenase; Triazines | 1997 |
Studies on Plasmodium vivax relapse pattern in Kheda district, Gujarat.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Female; Humans; India; Malaria, Vivax; Male; Primaquine; Pyrimethamine; Recurrence | 1996 |
Multi-drug resistant malaria in Sri Lanka.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria; Male; Plasmodium falciparum; Pyrimethamine; Sri Lanka; Sulfadoxine | 1996 |
In vitro susceptibility of Tanzanian wild isolates of Plasmodium falciparum to artemisinin, chloroquine, sulfadoxine/pyrimethamine and mefloquine.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Humans; Mefloquine; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Tanzania | 1997 |
Malaria in Mvumi, central Tanzania and the in vivo response of Plasmodium falciparum to chloroquine and sulphadoxine pyrimethamine.
Topics: Adolescent; Adult; Aged; Animals; Anopheles; Antimalarials; Child; Chloroquine; Cross-Sectional Studies; Culex; Drug Combinations; Drug Resistance; Humans; Insect Vectors; Malaria, Falciparum; Middle Aged; Prevalence; Pyrimethamine; Sulfadoxine; Tanzania | 1997 |
In vivo sensitivity of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in school children in Hoima district, western Uganda.
Topics: Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Pyrimethamine; Sulfadoxine | 1997 |
Efficacy of sulfadoxine-pyrimethamine in chloroquine resistant falciparum malaria in Bombay.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; India; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 1996 |
Modified antimalarial treatment for chloroquin resistant plasmodium falciparum infection.
Topics: Antimalarials; Chloroquine; Drug Resistance; Endemic Diseases; Humans; Malaria, Falciparum; Pyrimethamine; Quinine; Sulfadoxine | 1995 |
Malaria prophylaxis prescribed for travellers from New Zealand.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Utilization; Humans; Malaria; New Zealand; Practice Patterns, Physicians'; Pyrimethamine; Travel | 1997 |
Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic responses to standard antimalarial drugs in Nigeria.
Topics: Adolescent; Adult; Antimalarials; Artemether; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; L-Lactate Dehydrogenase; Malaria, Falciparum; Male; Monitoring, Physiologic; Nigeria; Phenanthrenes; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome | 1997 |
Synergism of cimetidine with anti-malarial agents.
Topics: Animals; Antimalarials; Chloroquine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Heme; Histamine H2 Antagonists; Plasmodium falciparum; Polymers; Proadifen; Pyrimethamine | 1997 |
Resistance of falciparum malaria to chloroquine and sulfadoxine-pyrimethamine in Afghan refugee settlements in western Pakistan: surveys by the general health services using a simplified in vivo test.
Topics: Adolescent; Adult; Afghanistan; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Pakistan; Pyrimethamine; Refugees; Sulfadoxine | 1997 |
A simplified in vivo drug sensitivity test for malaria in the field.
Topics: Adult; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Mefloquine; Myanmar; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors | 1997 |
A role for B cells in the development of T cell helper function in a malaria infection in mice.
Topics: Animals; B-Lymphocytes; Chloroquine; Erythrocytes; Female; Genes, Immunoglobulin; Immunoglobulin mu-Chains; Malaria; Mice; Mice, Knockout; Plasmodium chabaudi; Pyrimethamine; T-Lymphocyte Subsets; Th1 Cells; Th2 Cells | 1998 |
Antifolate-resistant malaria infections in Mpumalanga.
Topics: Antimalarials; Chloroquine; Drug Resistance, Multiple; Folic Acid Antagonists; Humans; Malaria, Falciparum; Pyrimethamine; South Africa; Sulfadoxine | 1998 |
Inhibition of the growth and development of asexual and sexual stages of drug-sensitive and resistant strains of the human malaria parasite Plasmodium falciparum by Neem (Azadirachta indica) fractions.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Pyrimethamine; Reproduction; Seeds | 1998 |
[Chemoprophylaxis of malaria in travelers to endemic zones].
Topics: Antimalarials; Chloroquine; Dapsone; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Proguanil; Pyrimethamine; Travel | 1998 |
A systematic approach to the development of a rational malaria treatment policy in Zambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Drug Resistance; Female; Health Policy; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Policy Making; Pyrimethamine; Statistics as Topic; Sulfadoxine; Time Factors; Zambia | 1998 |
Use of antimalarial drugs in Mali: policy versus reality.
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Consumer Behavior; Data Collection; Drug Combinations; Drug Utilization; Female; Health Knowledge, Attitudes, Practice; Humans; Interviews as Topic; Malaria; Male; Mali; Medicine, Traditional; Middle Aged; Proguanil; Pyrimethamine; Quinine; Rural Population; Suburban Population; Sulfadoxine | 1998 |
Safety of mefloquine and other antimalarial agents in the first trimester of pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Adverse Drug Reaction Reporting Systems; Antimalarials; Chloroquine; Databases, Factual; Drug Combinations; Drug Industry; Female; Humans; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Parasitic; Pregnancy Trimester, First; Proguanil; Prospective Studies; Pyrimethamine; Risk Factors; Safety; Sulfadoxine; Surveys and Questionnaires | 1998 |
Adverse effects of antimalarial prophylactic drugs: an important consideration in the risk-benefit equation.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Atovaquone; Azithromycin; Chloroquine; Drug Therapy, Combination; Humans; Malaria; Mefloquine; Naphthoquinones; Plasmodium falciparum; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Risk Assessment | 1998 |
[Evaluation of malaria chemoprevention among 359 pregnant women attending a health center in Dakar].
Topics: Adolescent; Adult; Antimalarials; Chemoprevention; Chloroquine; Female; Humans; Malaria; Maternal Health Services; Middle Aged; Patient Compliance; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Senegal | 1997 |
[The proper use of antimalarial drugs currently available].
Topics: Animals; Antimalarials; Chemoprevention; Chloroquine; Contraindications; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Malaria; Malaria, Falciparum; Malaria, Vivax; Mefloquine; Phenanthrenes; Plasmodium; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Quinine; Sulfadoxine; Travel | 1998 |
In vivo responses to antimalarials by Plasmodium falciparum and Plasmodium vivax from isolated Gag Island off northwest Irian Jaya, Indonesia.
Topics: Adolescent; Adult; Age Distribution; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Humans; Indonesia; Infant; Malaria, Falciparum; Malaria, Vivax; Parasitemia; Plasmodium falciparum; Plasmodium vivax; Prevalence; Pyrimethamine; Sulfadoxine | 1999 |
Does the availability of blood slide microscopy for malaria at health centers improve the management of persons with fever in Zambia?
Topics: Ambulatory Care Facilities; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Humans; Interviews as Topic; Malaria, Falciparum; Male; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Reproducibility of Results; Seasons; Sulfadoxine; Zambia | 1999 |
Efficacy and tolerability of a low-dose mefloquine-sulfadoxine-pyrimethamine combination compared with chloroquine in the treatment of acute malaria infection in a population with multiple drug-resistant Plasmodium falciparum.
Topics: Adolescent; Adult; Animals; Antimalarials; Blood; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Nigeria; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Random Allocation; Sulfadoxine | 1999 |
Chemotherapy of malaria and resistance to antimalarial drugs in Guayana area, Venezuela.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Female; Humans; Leukocytes; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Pyrimethamine; Random Allocation; Regression Analysis; Rural Population; Sulfadoxine; Tropical Climate; Venezuela | 1999 |
Plasmodium falciparum: drug-resistant malaria complicating leukemias and lymphomas in children.
Topics: Adolescent; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Infant; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Malaria, Falciparum; Male; Plasmodium falciparum; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimethamine; Quinine; Sulfalene | 1999 |
Plasmodium chabaudi: effect of antimalarial drugs on gametocytogenesis.
Topics: Animals; Antimalarials; Chloroquine; Gametogenesis; Malaria; Male; Mefloquine; Mice; Mice, Inbred C57BL; Plasmodium chabaudi; Pyrimethamine; Quinine | 1999 |
Antiplasmodial activity of selected sudanese medicinal plants with emphasis on Acacia nilotica.
Topics: Acacia; Animals; Antimalarials; Chloroquine; Drug Resistance; Humans; Lymphocyte Activation; Lymphocytes; Medicine, African Traditional; Phytotherapy; Plant Extracts; Plants, Medicinal; Plasmodium falciparum; Pyrimethamine; Species Specificity; Sudan; Tannins; Terpenes | 1999 |
Synergism of benflumetol and artemether in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Culture Media; Drug Resistance, Multiple; Drug Synergism; Ethanolamines; Fluorenes; Inhibitory Concentration 50; Lumefantrine; Plasmodium falciparum; Pyrimethamine; Sesquiterpenes | 1999 |
Current clinical efficacy of chloroquine for the treatment of Plasmodium falciparum infections in urban Dar es Salaam, United Republic of Tanzania.
Topics: Age Factors; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Humans; Infant; Malaria, Falciparum; Pyrimethamine; Sulfadoxine; Tanzania; Urban Population | 1999 |
Atovaquone-proguanil for falciparum malaria in the Philippines.
Topics: Antimalarials; Atovaquone; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Naphthoquinones; Philippines; Proguanil; Pyrimethamine; Sulfadoxine | 2000 |
Azithromycin: antimalarial profile against blood- and sporozoite-induced infections in mice and monkeys.
Topics: Animals; Anti-Bacterial Agents; Antimalarials; Azithromycin; Chloroquine; Doxycycline; Erythromycin; Female; Macaca mulatta; Malaria; Male; Mice; Parasitemia; Plasmodium cynomolgi; Plasmodium yoelii; Primaquine; Pyrimethamine | 2000 |
[Chloroquine sensitivity of Plasmodium falciparum at the Gamkalley Clinic and the Nigerian armed forces PMI (Niamey, Niger)].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Infant; Malaria, Falciparum; Nigeria; Parasitemia; Plasmodium falciparum; Pyrimethamine; Quinine; Recurrence; Sulfadoxine | 1999 |
Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro.
Topics: Amsacrine; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Naphthyridines; Norfloxacin; Nucleic Acid Synthesis Inhibitors; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Thailand; Topoisomerase II Inhibitors; Triazines | 2000 |
Population dynamics of Plasmodium falciparum in an unstable malaria area of eastern Sudan.
Topics: Alleles; Animals; Antigens, Protozoan; Antimalarials; Chloroquine; Cohort Studies; DNA Primers; DNA, Protozoan; Drug Combinations; Genetic Variation; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Seasons; Sudan; Sulfadoxine | 2000 |
Antibiotics for prophylaxis of Plasmodium falciparum infections: in vitro activity of doxycycline against Senegalese isolates.
Topics: Amodiaquine; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antimalarials; Artemether; Artemisinins; Chloroquine; Doxycycline; Drug Resistance; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Scintillation Counting; Senegal; Sesquiterpenes; Statistics, Nonparametric; Triazines | 2000 |
Epidemiologic tools for malaria surveillance in an urban setting of low endemicity along the Colombian Pacific coast.
Topics: Animals; Antimalarials; Blood; Blotting, Southern; Chloroquine; Colombia; Cross-Sectional Studies; DNA Primers; DNA, Protozoan; Drug Combinations; Electrophoresis, Agar Gel; Female; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Primaquine; Pyrimethamine; Reagent Kits, Diagnostic; Sensitivity and Specificity; Sentinel Surveillance; Sulfadoxine; Urban Population | 2000 |
Management of a case of chloroquine-resistant falciparum malaria in a pregnant woman with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Malaria, Falciparum; Mefloquine; Microbial Sensitivity Tests; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pyrimethamine | 1999 |
Gametocytemia and infectivity to mosquitoes of patients with uncomplicated Plasmodium falciparum malaria attacks treated with chloroquine or sulfadoxine plus pyrimethamine.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Animals; Anopheles; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Insect Vectors; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Plasmodium falciparum; Prevalence; Pyrimethamine; Senegal; Sulfadoxine | 2000 |
An unusual case of multidrug-resistant Plasmodium vivax malaria in Mumbai (Bombay), India.
Topics: Adolescent; Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Humans; India; Malaria, Vivax; Male; Mefloquine; Plasmodium vivax; Primaquine; Pyrimethamine; Sesquiterpenes; Sulfadoxine | 2000 |
Chloroquine resistant malaria.
Topics: Africa South of the Sahara; Anti-Bacterial Agents; Antimalarials; Chloroquine; Doxycycline; Drug Antagonism; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Patient Selection; Pyrimethamine; Quinine; Sulfadoxine | 2000 |
In vivo sensitivity of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine among schoolchildren in rural Uganda: a comparison between 1995 and 1998.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Humans; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Pyrimethamine; Rural Population; Students; Sulfadoxine; Time Factors; Uganda | 2000 |
Chloroquine- and sulfadoxine-pyrimethamine-resistant Falciparum malaria in vivo - a pilot study in rural Zambia.
Topics: Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Follow-Up Studies; Humans; Infant; Malaria, Falciparum; Male; Pilot Projects; Plasmodium falciparum; Pyrimethamine; Rural Health; Sulfadoxine; Zambia | 2000 |
Comparative clinical characteristics and response to oral antimalarial therapy of children with and without Plasmodium falciparum hyperparasitaemia in an endemic area.
Topics: Adolescent; Age Factors; Analysis of Variance; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; Endemic Diseases; Female; Heart Rate; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Prospective Studies; Pyrimethamine; Sulfadoxine; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2000 |
Patterns of care for childhood malaria in Zambia.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Female; Fever; Health Care Surveys; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Infant; Interviews as Topic; Malaria; Male; Patient Acceptance of Health Care; Pyrimethamine; Seizures; Sulfadoxine; Zambia | 2000 |
Treatment of uncomplicated Plasmodium falciparum malaria in Myanmar: a clinical decision analysis.
Topics: Antimalarials; Chloroquine; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Drug Combinations; Humans; Malaria, Falciparum; Mefloquine; Myanmar; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2000 |
Effects of anti-protozoal drugs and histopathological studies on trypanosome species.
Topics: Animals; Chloroquine; Female; Humans; Male; Metronidazole; Parasitic Sensitivity Tests; Phenanthrenes; Pyrimethamine; Rats; Trypanosoma; Trypanosomiasis | 2001 |
Parasitaemia and gametocytaemia after treatment with chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/sulfadoxine combined with artesunate in young Gambians with uncomplicated malaria.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Chloroquine; Cost-Benefit Analysis; Disease Transmission, Infectious; Drug Combinations; Female; Gambia; Gametogenesis; Humans; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Random Allocation; Rural Health; Seasons; Sesquiterpenes; Sulfadoxine; Time Factors; Treatment Outcome | 2001 |
[Resistance of Plasmodium falciparum to 3 antimalarials in Turbo (Antioquia, Colombia), 1998].
Topics: Adolescent; Adult; Aged; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Colombia; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2001 |
[Drug resistance of Plasmodium falciparum in coastal regions of Madagascar].
Topics: Adolescent; Animals; Child; Child, Preschool; Chloroquine; Drug Resistance; Drug Therapy, Combination; Humans; Madagascar; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2000 |
In vitro activities of DU-1102, a new trioxaquine derivative, against Plasmodium falciparum isolates.
Topics: Aminoquinolines; Animals; Antimalarials; Bridged Bicyclo Compounds, Heterocyclic; Chloroquine; Plasmodium falciparum; Pyrimethamine; Regression Analysis | 2001 |
HIV infection may adversely affect clinical response to chloroquine therapy for uncomplicated malaria in children.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Follow-Up Studies; HIV Antibodies; HIV-1; Humans; Infant; Malaria, Falciparum; Middle Aged; Pyrimethamine; Sulfadoxine; Treatment Outcome; Uganda | 2001 |
Potent antimalarial activities of polyether antibiotic, X-206.
Topics: Actinomycetales; Animals; Anti-Bacterial Agents; Antimalarials; Artemether; Artemisinins; Artesunate; Cell Death; Cell Line; Chloroquine; Drug Resistance; Embryo, Mammalian; Embryo, Nonmammalian; Ethers, Cyclic; Humans; Malaria; Mice; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes | 2001 |
Plasmodium falciparum pfcrt and pfmdr1 polymorphisms are associated with the pfdhfr N108 pyrimethamine-resistance mutation in isolates from Ghana.
Topics: Adolescent; Adult; Animals; Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; DNA, Protozoan; Drug Resistance; Female; Ghana; Humans; Infectious Disease Transmission, Vertical; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Protozoan Proteins; Pyrimethamine; Tetrahydrofolate Dehydrogenase | 2001 |
Prevalence of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum isolates from southern Mauritania.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Disease Outbreaks; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Mauritania; Middle Aged; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2001 |
History and importance of antimalarial drug resistance.
Topics: Africa; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; History, 20th Century; History, 21st Century; Humans; Malaria, Falciparum; Mosquito Control; Pyrimethamine; Sulfadoxine; Treatment Outcome; World Health Organization | 2001 |
Monitoring antimalarial drug resistance within National Malaria Control Programmes: the EANMAT experience.
Topics: Africa, Eastern; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Geography; Health Care Rationing; Humans; International Cooperation; Malaria; National Health Programs; Pyrimethamine; Sentinel Surveillance; Sulfadoxine | 2001 |
Perception of chloroquine efficacy and alternative treatments for uncomplicated malaria in children in a holoendemic area of Tanzania: implications for the change of treatment policy.
Topics: Adolescent; Adult; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Endemic Diseases; Health Care Surveys; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria; Middle Aged; Pyrimethamine; Sulfadoxine; Surveys and Questionnaires; Tanzania; Treatment Outcome | 2001 |
Changing the first line drug for malaria treatment--cost-effectiveness analysis with highly uncertain inter-temporal trade-offs.
Topics: Africa South of the Sahara; Antimalarials; Case Management; Child; Child, Preschool; Chloroquine; Cost-Benefit Analysis; Decision Trees; Drug Combinations; Drug Costs; Drug Resistance; Drugs, Essential; Health Policy; Humans; Malaria; Models, Econometric; Patient Compliance; Pyrimethamine; Quality-Adjusted Life Years; Sulfadoxine | 2001 |
African scientists discuss drug-resistant malaria.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Malaria; Plasmodium; Pyrimethamine; Sulfadoxine; Uganda | 2002 |
Resistance of Plamodium falciparum to antimalarial drugs in Zaragoza (Antioquia, Colombia), 1998.
Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Chloroquine; Colombia; Drug Resistance; Humans; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2002 |
The drug sensitivity and transmission dynamics of human malaria on Nias Island, North Sumatra, Indonesia.
Topics: Adolescent; Adult; Age Distribution; Aged; Animals; Anopheles; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Follow-Up Studies; Humans; Indonesia; Insect Vectors; Malaria, Falciparum; Malaria, Vivax; Middle Aged; Plasmodium vivax; Prevalence; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2002 |
Resistance to antimalarials.
Topics: Africa; Antimalarials; Chloroquine; Developing Countries; Drug Combinations; Drug Resistance, Multiple; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Pyrimethamine; Sulfadoxine; Survival Analysis | 2002 |
Molecular epidemiology of malaria in Cameroon. X. Evaluation of PFMDR1 mutations as genetic markers for resistance to amino alcohols and artemisinin derivatives.
Topics: Adolescent; Adult; Amodiaquine; Animals; Antimalarials; Base Sequence; Cameroon; Child; Child, Preschool; Chloroquine; DNA Primers; Drug Combinations; Drug Resistance, Multiple; Genetic Markers; Humans; Malaria, Falciparum; Molecular Epidemiology; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfadoxine | 2002 |
Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America.
Topics: Alleles; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Cloning, Molecular; Drug Resistance, Multiple; Folic Acid Antagonists; Haplotypes; Humans; Malaria, Falciparum; Microsatellite Repeats; Molecular Sequence Data; Multienzyme Complexes; Mutation; Plasmodium falciparum; Pyrimethamine; South America; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase | 2002 |
Monitoring the drug-sensitivity of Plasmodium falciparum in coastal towns in Madagascar by use of in vitro chemosensitivity and mutation detection tests.
Topics: Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Drug Resistance, Multiple; Drug Therapy, Combination; Genotype; Humans; Madagascar; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2002 |
Therapeutic efficacy of chloroquine and sulfadoxine/pyrimethamine against Plasmodium falciparum infection in Somalia.
Topics: Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Pyrimethamine; Somalia; Sulfadoxine; Treatment Outcome | 2002 |
Diagnostic value of molecular markers in chloroquine-resistant falciparum malaria in Southern Mauritania.
Topics: Adult; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Genetic Markers; Humans; Malaria, Falciparum; Male; Mauritania; Mutation; Odds Ratio; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine | 2002 |
A molecular surveillance system for global patterns of drug resistance in imported malaria.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Genetic Markers; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Mutation; Plasmodium falciparum; Population Surveillance; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Travel | 2003 |
Chloroquine or sulfadoxine-pyrimethamine for the treatment of uncomplicated, Plasmodium falciparum malaria during an epidemic in Central Java, Indonesia.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Disease Outbreaks; Drug Combinations; Drug Resistance; Female; Humans; Incidence; Indonesia; Malaria, Falciparum; Male; Middle Aged; Prevalence; Pyrimethamine; Sulfadoxine; Treatment Failure | 2002 |
[Comparison of three approaches to prevent falciparum malaria in Chinese who worked in an African country with high endemicity of malaria].
Topics: Adult; Antimalarials; Chloroquine; Communicable Disease Control; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Mosquito Control; Pyrimethamine | 2001 |
[Malaria study in the cyclone risk zone: entomological , diagnostic and therapeutic approach in the southeastern region of Madagascar].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Anopheles; Antimalarials; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Disasters; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Insect Vectors; Madagascar; Malaria; Male; Middle Aged; Mosquito Control; Parasitic Sensitivity Tests; Population Density; Population Surveillance; Prevalence; Pyrimethamine; Risk Factors; Seasons; Sulfadoxine; Surveys and Questionnaires; Treatment Outcome | 2002 |
The hospital- and field-based performances of the OptiMAL test, for malaria diagnosis and treatment monitoring in central India.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; False Negative Reactions; False Positive Reactions; Female; Humans; Immunologic Tests; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine | 2003 |
In vitro sensitivity of Plasmodium falciparum to amodiaquine compared with other major antimalarials in Madagascar.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Multiple; Humans; Inhibitory Concentration 50; Madagascar; Malaria, Falciparum; Mefloquine; Parasitemia; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinine; Triazines | 2002 |
Malaria in Austria 1990-2000.
Topics: Adolescent; Adult; Age Distribution; Animals; Austria; Chemoprevention; Child; Child, Preschool; Chloroquine; Disease Notification; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Mefloquine; Patient Compliance; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Proguanil; Pyrimethamine; Sex Distribution; Sulfadoxine | 2003 |
Health seeking behavior by families of children suspected to have malaria in Kabale: Uganda.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Family; Female; Health Facilities; Health Knowledge, Attitudes, Practice; Health Services Accessibility; Humans; Infant; Malaria, Falciparum; Male; Medicine, African Traditional; Patient Acceptance of Health Care; Pyrimethamine; Quinine; Sulfadoxine; Uganda | 2002 |
Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi.
Topics: Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Malaria, Falciparum; Malawi; Male; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors | 2003 |
Molecular survey of Plasmodium falciparum resistance in south-eastern Iran.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Female; Genes, Protozoan; Humans; Iran; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2003 |
Surveillance of in vivo resistance of Plasmodium falciparum to antimalarial drugs from 1992 to 1999 in Malabo (Equatorial Guinea).
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Equatorial Guinea; Humans; Infant; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine | 2003 |
Vendor-to-vendor education to improve malaria treatment by private drug outlets in Bungoma District, Kenya.
Topics: Adult; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Commerce; Drug Combinations; Female; Guideline Adherence; Health Education; Humans; Kenya; Malaria; Male; Pyrimethamine; Rural Health Services; Sulfadoxine; Urban Health Services | 2003 |
Mapping of the Plasmodium falciparum multidrug resistance gene 5'-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites.
Topics: 5' Untranslated Regions; Animals; Antimalarials; ATP-Binding Cassette Transporters; Base Sequence; Chloroquine; Chromosome Mapping; Drug Resistance, Multiple; Gene Expression Regulation; Genes, MDR; Genes, Protozoan; Genes, Reporter; Luciferases; Mefloquine; Molecular Sequence Data; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Quinine; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Nucleic Acid; Transcription, Genetic | 2003 |
Evaluation of the antimalarial properties and standardization of tablets of Azadirachta indica (Meliaceae) in mice.
Topics: Administration, Oral; Animals; Antimalarials; Azadirachta; Chloroquine; Malaria; Mice; Parasitic Sensitivity Tests; Phytotherapy; Plant Bark; Plant Extracts; Plant Leaves; Plasmodium yoelii; Pyrimethamine; Tablets | 2003 |
Asymptomatic, recrudescent, chloroquine-resistant Plasmodium falciparum infections in Nigerian children: clinical and parasitological characteristics and implications for the transmission of drug-resistant parasites.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Mefloquine; Nigeria; Plasmodium falciparum; Prevalence; Pyrimethamine; Recurrence; Statistics as Topic; Sulfadoxine; Treatment Failure | 2003 |
Plasmodium falciparum: correlation of in vivo resistance to chloroquine and antifolates with genetic polymorphisms in isolates from the south of Lao PDR.
Topics: Adolescent; Adult; Aged; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Folic Acid Antagonists; Humans; Infant; Laos; Malaria, Falciparum; Middle Aged; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine | 2003 |
Intensity of transmission and spread of gene mutations linked to chloroquine and sulphadoxine-pyrimethamine resistance in falciparum malaria.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2003 |
A comparison of the antimalarial effects of suppressive doses of chloroquine, amodiaquin, and pyrimethamine.
Topics: Amodiaquine; Antimalarials; Chloroquine; Humans; Malaria; Pyrimethamine | 1954 |
Chronic discoid lupus erythematosus: treatment with daraprim and chloroquine diphosphate (aralen).
Topics: Antimalarials; Chloroquine; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Pyrimethamine | 1954 |
Pyrimethamine (daraprim) in malaria.
Topics: Antimalarials; Chloroquine; Humans; Malaria; Pyrimethamine | 1953 |
Therapeutic trials with pyrimethamine (daraprim), resochin, amodiaquin (camoquin) and quinine.
Topics: Amodiaquine; Antimalarials; Chloroquine; Humans; Malaria; Pyrimethamine; Quinine | 1953 |
The treatment of acute malaria with single oral doses of amodiaquin, chloroquine, hydroxychloroquine and pyrimethamine.
Topics: Amodiaquine; Antimalarials; Chloroquine; Humans; Hydroxychloroquine; Malaria; Pyrimethamine | 1954 |
The treatment of Plasmodium falciparum infection with chloroquine, with a note on infectivity to mosquitoes of primaquine- and pyrimethamine-treated cases.
Topics: Animals; Antimalarials; Chloroquine; Culicidae; Humans; Malaria, Falciparum; Plasmodium falciparum; Primaquine; Pyrimethamine | 1956 |
[Effect of single doses of combined chloroquine and pyrimethamine].
Topics: Antimalarials; Chloroquine; Humans; Hyperthermia, Induced; Neurosyphilis; Pyrimethamine | 1957 |
Chloroquine or pyrimethamine in salt as a supressive against sporozoite-induced vivax malaria (Chesson strain).
Topics: Animals; Antimalarials; Chloroquine; Humans; Malaria; Malaria, Vivax; Military Personnel; Pyrimethamine; Sodium Chloride, Dietary; Sporozoites | 1958 |
[The prophylaxis of malaria by addition of chloroquine and pyrimethamine to table salt].
Topics: Chloroquine; Diet; Humans; Malaria; Nutrition Assessment; Nutritional Status; Pyrimethamine; Sodium Chloride; Sodium Chloride, Dietary | 1960 |
[Comparison of the effectiveness of chloroquin and pyrimethamine as prophylactic antimalarial drugs].
Topics: Antimalarials; Chloroquine; Humans; Pyrimethamine | 1960 |
Nephrosis in Nigerian children. Role of Plasmodium malariae, and effect of antimalarial treatment.
Topics: Antimalarials; Child; Chloroquine; Humans; Malaria; Nephrotic Syndrome; Plasmodium malariae; Primaquine; Pyrimethamine | 1963 |
Studies on the toxicity and action of diaminodiphenyl-sulfone (DDS) in avian and simian malaria.
Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Malaria; Malaria, Avian; Proguanil; Pyrimethamine; Quinine | 1962 |
Oral contraceptives. VII. Antimalarials as antifertility agents.
Topics: Amodiaquine; Antimalarials; Chloroquine; Contraceptive Agents; Contraceptives, Oral; Female; Humans; Proguanil; Pyrimethamine; Quinacrine | 1962 |
DRUG RESISTANCE IN PLASMODIUM FALCIPARUM FROM THAILAND.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Thailand | 1963 |
BLACKWATER FEVER AFTER THE USE OF CHLOROQUINE-PYRIMETHAMINE.
Topics: Blackwater Fever; Chloroquine; Hemolysis; Humans; Malaria; New Guinea; Pyrimethamine; Quinine; Toxicology | 1963 |
PLASMODIUM FALCIPARUM RESISTANT TO CHLOROQUINE IN CAMBODIA.
Topics: Cambodia; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Pyrimethamine; Quinine | 1963 |
ANTIMALARIAL DRUG TRIALS ON A MULTIRESISTANT STRAIN OF PLASMODIUM FALCIPARUM.
Topics: Amodiaquine; Antimalarials; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Thailand | 1963 |
[MALARIA PREVENTION IN NEW GUINEA WITH DRUGS ADDED TO KITCHEN SALT].
Topics: Chloroquine; DDT; Humans; Malaria; Mosquito Control; New Guinea; Pyrimethamine; Sodium Chloride | 1963 |
DRUG-RESISTANT FALCIPARUM MALARIA FROM CAMBODIA AND MALAYA.
Topics: Animals; Cambodia; Chloroquine; Culicidae; Drug Resistance; Drug Resistance, Microbial; Humans; Malaria; Malaria, Falciparum; Malaysia; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine | 1963 |
AN EVALUATION OF ANTIMALARIAL COMBINATIONS AGAINST PLASMODIUM BERGHEI IN THE MOUSE.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Erythrocytes; Mice; Plasmodium; Plasmodium berghei; Primaquine; Pyrimethamine; Research | 1963 |
CONTROLLED TRIAL OF PYRIMETHAMINE IN PREGNANT WOMEN IN AN AFRICAN VILLAGE.
Topics: Birth Weight; Chloroquine; Female; Humans; Infant; Infant Mortality; Lactose; Malaria; Nigeria; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Pyrimethamine; Statistics as Topic | 1964 |
STUDIES IN THE ACQUISITION OF IMMUNITY OF PLASMODIUM FALCIPARUM INFECTIONS IN AFRICA.
Topics: Adolescent; Africa; Africa, Western; Allergy and Immunology; Child; Chloroquine; Humans; Infant; Malaria; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Serum Albumin; Serum Globulins | 1964 |
FLUORESCENT ANTIBODY STUDIES IN HUMAN MALARIA. II. DEVELOPMENT AND PERSISTENCE OF ANTIBODIES TO PLASMODIUM FALCIPARUM.
Topics: Amodiaquine; Antibodies; Antigen-Antibody Reactions; Chloroquine; Fluorescent Antibody Technique; Humans; Immune Sera; Malaria; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine; Vaccination | 1964 |
P. FALCIPARUM INFECTION IN CHILDREN: TREATMENT WITH A CHLOROQUINE-PYRIMETHAMINE SYRUP (DARACLOR); PRELIMINARY OBSERVATIONS.
Topics: Child; Chloroquine; Humans; Infant; Plasmodium falciparum; Pyrimethamine; Serologic Tests; Toxicology | 1964 |
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM THAILAND.
Topics: Amodiaquine; Antimalarials; Asia, Southeastern; Biomedical Research; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Humans; Hydroxychloroquine; Malaria; Malaria, Falciparum; Pharmacology; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Thailand | 1964 |
A MALARIA ERADICATION EXPERIMENT IN THE HIGHLANDS OF KIGEZI (UGANDA).
Topics: Chloroquine; DDT; Epidemiology; Humans; Malaria; Pyrimethamine; Uganda | 1964 |
DRUG-RESISTANCE IN FALCIPARUM MALARIA IN SOUTH-EAST ASIA.
Topics: Adolescent; Asia, Southeastern; Child; Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Plasmodium falciparum; Proguanil; Pyrimethamine; Quinacrine; Quinine; Statistics as Topic; Toxicology | 1964 |
[CAMPAIGN AGAINST MALARIA WITH MEDICATED SALT IN NEW GUINEA].
Topics: Chloroquine; Humans; Malaria; New Guinea; Pharmacology; Pyrimethamine; Quinolines; Sodium Chloride | 1964 |
ROLE OF P-AMINOBENZOIC ACID IN PLASMODIUM BERGHEI INFECTION IN THE MOUSE.
Topics: 4-Aminobenzoic Acid; Aminopterin; Animals; Chloroquine; Folic Acid; Folic Acid Deficiency; Leucovorin; Malaria; Mice; Pharmacology; Plasmodium berghei; Pyrimethamine; Research | 1964 |
THE CONTROL OF EPIDEMIC MALARIA IN THE HIGHLANDS OF WESTERN KENYA. 3. AFTER THE CAMPAIGN.
Topics: Adolescent; Animals; Anopheles; Child; Chloroquine; Communicable Disease Control; Dieldrin; Drug Therapy; Epidemics; Epidemiology; Humans; Infant; Insect Vectors; Kenya; Malaria; Pyrimethamine | 1964 |
THE USE OF MEDICATED SALT IN AN ANTIMALARIA CAMPAIGN IN WEST NEW GUINEA.
Topics: Antimalarials; Chloroquine; Epidemiology; Humans; Indonesia; Malaria; New Guinea; Pyrimethamine; Sodium Chloride; Statistics as Topic | 1964 |
CHEMOTHERAPY OF CUTANEOUS LEISHMANIASIS: LEISHMANIA TROPICA INFECTIONS IN MICE.
Topics: Amidines; Animals; Antimony; Antiprotozoal Agents; Chloroquine; Chlortetracycline; Dapsone; Deoxyribonuclease I; Emetine; Hyaluronoglucosaminidase; Hydrastis; Leishmania tropica; Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Mucocutaneous; Mice; Pathology; Pharmacology; Primaquine; Pyrimethamine; Quinacrine; Research; Streptodornase and Streptokinase; Streptokinase; Sulfonamides; Surface-Active Agents; Toxicology | 1964 |
APPARENT REFRACTORINESS TO CHLOROQUINE, PYRIMETHAMINE, AND QUININE IN STRAINS OF PLASMODIUM FALCIPARUM FROM VIETNAM.
Topics: Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Military Medicine; Plasmodium falciparum; Pyrimethamine; Quinine; Vietnam | 1965 |
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM VIET-NAM.
Topics: Amodiaquine; Antimalarials; Biomedical Research; Chloroquine; Drug Therapy; Humans; Malaria; Malaria, Falciparum; Pharmacology; Plasmodium falciparum; Pyrimethamine; Quinine; Statistics as Topic; Vietnam | 1964 |
CHLOROQUINE-RESISTANT STRAIN OF PLASMODIUM FALCIPARUM FROM KHAO MAI KHAEO, THAILAND.
Topics: Chloroquine; Drug Resistance; Drug Resistance, Microbial; Drug Therapy; Humans; Malaria; Plasmodium falciparum; Primaquine; Pyrimethamine; Quinine; Thailand | 1965 |
MALARIA IN CHILDHOOD MODERN CONCEPTS OF IMMUNITY, TREATMENT, PROPHYLAXIS.
Topics: Amodiaquine; Child; Chloroquine; Diagnosis; Drug Therapy; Epidemiology; Humans; Infant; Infant, Newborn; Malaria; Proguanil; Pyrimethamine | 1965 |
SOME FEATURES OF MALARIA IN DILI, PORTUGUESE TIMOR, DURING 1963-64.
Topics: Amodiaquine; Anemia; Chloroquine; Clinical Laboratory Techniques; Drug Therapy; Epidemiology; Humans; Indonesia; Malaria; Proguanil; Pyrimethamine; Seasons | 1965 |
Molecular epidemiology of malaria in Cameroon. XV. Experimental studies on serum substitutes and supplements and alternative culture media for in vitro drug sensitivity assays using fresh isolates of Plasmodium falciparum.
Topics: Amodiaquine; Animals; Antimalarials; Cameroon; Chloroquine; Culture Media; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Serum Albumin | 2003 |
The efficacy of antimalarial monotherapies, sulphadoxine-pyrimethamine and amodiaquine in East Africa: implications for sub-regional policy.
Topics: Africa, Eastern; Amodiaquine; Antimalarials; Chloroquine; Disease Susceptibility; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Health Policy; Humans; Malaria; Parasitic Sensitivity Tests; Predictive Value of Tests; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2003 |
Evaluation of a simple operational approach for monitoring resistance to antimalarial drugs in Peru.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Monitoring; Drug Resistance; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Peru; Pyrimethamine; Quality of Health Care; Sulfadoxine; Treatment Failure | 2003 |
Application of a multi-faceted approach for the assessment of treatment response in falciparum malaria: a study from Malaysian Borneo.
Topics: Animals; Antimalarials; Borneo; Chloroquine; Drug Resistance, Multiple; Genes, MDR; Genes, Protozoan; Genetic Markers; Humans; Malaria, Falciparum; Plasmodium falciparum; Point Mutation; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2003 |
Diagnosis and treatment of malaria in children.
Topics: Animals; Antimalarials; Atovaquone; Child; Chloroquine; Drug Combinations; Humans; Malaria; Malaria, Falciparum; Mefloquine; Naphthoquinones; Plasmodium falciparum; Proguanil; Pyrimethamine; Sulfadoxine | 2003 |
Molecular assessment of drug resistance in Plasmodium falciparum from Bahr El Gazal province, Sudan.
Topics: Animals; Antimalarials; ATP-Binding Cassette Transporters; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Gene Frequency; Genotype; Humans; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Failure | 2003 |
Therapeutic efficacies of antimalarial drugs in the treatment of uncomplicated, Plasmodium falciparum malaria in Assam, north-eastern India.
Topics: Adolescent; Adult; Aged; Animals; Anti-Infective Agents; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; India; Infant; Malaria, Falciparum; Male; Middle Aged; Parasitemia; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2003 |
Evolution of drug-resistance genes in Plasmodium falciparum in an area of seasonal malaria transmission in Eastern Sudan.
Topics: Alleles; Animals; Antimalarials; Chloroquine; Cross-Sectional Studies; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Microsatellite Repeats; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Regression Analysis; Seasons; Sequence Analysis, DNA; Sudan; Sulfadoxine | 2004 |
Monitoring antimalarial drug efficacy.
Topics: Animals; Antimalarials; Chloroquine; Drug Monitoring; Drug Resistance; Humans; Laos; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome; World Health Organization | 2004 |
Defective DNA repair as a potential mechanism for the rapid development of drug resistance in Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; DNA Damage; DNA Repair; Drug Resistance; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Mefloquine; Parasitic Sensitivity Tests; Phenanthrenes; Plasmodium falciparum; Pyrimethamine; Quinine; Sesquiterpenes; Sulfanilamide; Sulfanilamides; Ultraviolet Rays | 2004 |
Comparative efficacy of chloroquine and sulfadoxine-pyrimethamine for uncomplicated Plasmodium falciparum malaria and impact on gametocyte carriage rates in the East Nusatenggara province of Indonesia.
Topics: Adolescent; Adult; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Pyrimethamine; Sulfadoxine | 2004 |
Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh.
Topics: Adolescent; Adult; Animals; Antimalarials; ATP-Binding Cassette Transporters; Bangladesh; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genetic Markers; Genotype; Humans; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Quinine; Sulfadoxine; Treatment Outcome | 2004 |
Molecular diagnosis of resistance to antimalarial drugs during epidemics and in war zones.
Topics: Animals; Antimalarials; Chloroquine; Cross-Sectional Studies; Disease Outbreaks; DNA, Protozoan; Drug Combinations; Drug Resistance, Microbial; Genes, Protozoan; Genetic Markers; Humans; Malaria, Falciparum; Mali; Molecular Epidemiology; Plasmodium falciparum; Polymerase Chain Reaction; Prevalence; Pyrimethamine; Sulfadoxine; Warfare | 2004 |
Intercontinental spread of pyrimethamine-resistant malaria.
Topics: Africa; Alleles; Animals; Antimalarials; Asia, Southeastern; Chloroquine; Drug Resistance; Drug Therapy, Combination; Evolution, Molecular; Genes, Protozoan; Genotype; Humans; Malaria, Falciparum; Microsatellite Repeats; Mutation; Plasmodium falciparum; Pyrimethamine; Tetrahydrofolate Dehydrogenase | 2004 |
Plasmodium falciparum resistant to chloroquine and to pyrimethamine in Comoros.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Comoros; DNA, Protozoan; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Treatment Outcome | 2004 |
Influence of chemotherapy on the Plasmodium gametocyte sex ratio of mice and humans.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falciparum; Male; Mice; Plasmodium; Pyrimethamine; Sex Ratio; Species Specificity; Sulfadoxine; Time Factors | 2004 |
Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda.
Topics: Alleles; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance, Multiple; Drug Therapy, Combination; Genetic Variation; Humans; Infant; Malaria, Falciparum; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Time Factors; Uganda | 2004 |
High prevalence of markers for sulfadoxine and pyrimethamine resistance in Plasmodium falciparum in the absence of drug pressure in the Ashanti region of Ghana.
Topics: Adult; Animals; Antimalarials; Biomarkers; Chloroquine; Drug Combinations; Drug Resistance; Humans; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2005 |
A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzy
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; DNA Primers; DNA, Protozoan; Drug Combinations; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pyrimethamine; Sulfadoxine; Tanzania; Tetrahydrofolate Dehydrogenase | 2005 |
Evaluation of chloroquine (CQ) and sulphadoxine/pyrimethamine (SP) therapy in uncomplicated falciparum malaria in Indo-Myanmar border areas.
Topics: Adolescent; Adult; Age Distribution; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Evaluation; Drug Resistance; Female; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sex Distribution; Sulfadoxine; Treatment Failure; Treatment Outcome | 2005 |
Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine.
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Hemoglobins; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Parasitemia; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2005 |
Efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, chloroquine-sulfadoxine-pyrimethamine combination, and amodiaquine-sulfadoxine-pyrimethamine combination in Central African children with noncomplicated malaria.
Topics: Amodiaquine; Antimalarials; Central African Republic; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Sulfadoxine | 2005 |
Plasmodium falciparum: higher incidence of molecular resistance markers for sulphadoxine than for pyrimethamine in Kasangati, Uganda.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Codon; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Genetic Markers; Haplotypes; Humans; Infant; Malaria, Falciparum; Male; Mutation; Plasmodium falciparum; Polymorphism, Restriction Fragment Length; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Treatment Outcome; Uganda | 2005 |
The pattern of home treatment of malaria in under-fives in south eastern Nigeria.
Topics: Adult; Antimalarials; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Female; Health Care Surveys; Home Nursing; Humans; Infant; Infant, Newborn; Interviews as Topic; Malaria; Mothers; Nigeria; Pyrimethamine; Self Medication; Sulfadoxine | 2005 |
The quality of antimalarials available in Yemen.
Topics: Antimalarials; Chloroquine; Dosage Forms; Drug Combinations; Product Surveillance, Postmarketing; Pyrimethamine; Quality Control; Sulfadoxine; Yemen | 2005 |
Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative.
Topics: Amodiaquine; Animals; Antimalarials; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Infant; Malaria, Falciparum; Male; Membrane Proteins; Membrane Transport Proteins; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Uganda | 2005 |
Selection strength and hitchhiking around two anti-malarial resistance genes.
Topics: Animals; Antimalarials; Chloroquine; Chromosomes; Drug Resistance; Genetic Carrier Screening; Genetic Variation; Genotype; Laos; Linkage Disequilibrium; Membrane Proteins; Membrane Transport Proteins; Microsatellite Repeats; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Selection, Genetic; Tetrahydrofolate Dehydrogenase; Thailand | 2005 |
Effectiveness of antimalarial drugs.
Topics: Adult; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Malaria, Falciparum; Pyrimethamine; Sulfadoxine | 2005 |
Effectiveness of antimalarial drugs.
Topics: Africa; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Pyrimethamine; Risk; Sulfadoxine | 2005 |
Detection of Plasmodium falciparum in pregnancy by laser desorption mass spectrometry.
Topics: Adult; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Malaria, Falciparum; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfadoxine | 2005 |
Epidemiology of drug-resistant malaria in Republic of Congo: using molecular evidence for monitoring antimalarial drug resistance combined with assessment of antimalarial drug use.
Topics: Antimalarials; Biomarkers; Child, Preschool; Chloroquine; Congo; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Genotype; Humans; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Patient Compliance; Polymerase Chain Reaction; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Treatment Outcome; Urban Health | 2005 |
Adoption of the new antimalarial drug policy in Tanzania--a cross-sectional study in the community.
Topics: Antimalarials; Artemisinins; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Female; Focus Groups; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Malaria, Falciparum; Male; Patient Acceptance of Health Care; Population Surveillance; Pyrimethamine; Rural Health; Self Administration; Sesquiterpenes; Sulfadoxine; Tanzania | 2005 |
Treatment of paediatric malaria during a period of drug transition to artemether-lumefantrine in Zambia: cross sectional study.
Topics: Ambulatory Care; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Prescriptions; Ethanolamines; Fluorenes; Health Policy; Humans; Malaria; Pyrimethamine; Sesquiterpenes; Sulfadoxine; Treatment Outcome; Zambia | 2005 |
Research influence on antimalarial drug policy change in Tanzania: case study of replacing chloroquine with sulfadoxine-pyrimethamine as the first-line drug.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Health Policy; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Research; Sulfadoxine; Tanzania; World Health Organization | 2005 |
Increased density but not prevalence of gametocytes following drug treatment of Plasmodium falciparum.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Middle Aged; Plasmodium falciparum; Prevalence; Pyrimethamine; Reverse Transcriptase Polymerase Chain Reaction; Sudan; Sulfadoxine | 2006 |
Spectrophotometric study of the reaction mechanism between DDQ Pi- and iodine sigma-acceptors and chloroquine and pyrimethamine drugs and their determination in pure and in dosage forms.
Topics: Antimalarials; Chloroquine; Dosage Forms; Iodine; Kinetics; Pyrimethamine; Spectrophotometry; Thermodynamics | 2005 |
Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad.
Topics: Amodiaquine; Animals; Chad; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Genes, Protozoan; Genotype; Humans; Infant; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Prospective Studies; Pyrimethamine; Sulfadoxine; Treatment Outcome; Urban Population | 2006 |
How sulfadoxine-pyrimethamine (SP) was perceived in some rural communities after phasing out chloroquine (CQ) as a first-line drug for uncomplicated malaria in Tanzania: lessons to learn towards moving from monotherapy to fixed combination therapy.
Topics: Antimalarials; Attitude to Health; Chloroquine; Drug Combinations; Drug Therapy, Combination; Focus Groups; Humans; Malaria; Patient Acceptance of Health Care; Perception; Pyrimethamine; Rural Population; Sulfadoxine; Tanzania | 2006 |
CD4 T cell activation as a predictor for treatment failure in Ugandans with Plasmodium falciparum malaria.
Topics: Adolescent; Adult; Age Factors; Animals; Antimalarials; Body Temperature; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Humans; Lymphocyte Activation; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Pyrimethamine; Risk Factors; Sulfadoxine; Treatment Failure; Uganda | 2006 |
Frequency distribution of antimalarial drug-resistant alleles among isolates of Plasmodium falciparum in Bangui, Central African Republic.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Central African Republic; Chloroquine; Drug Combinations; Drug Resistance, Multiple; Gene Frequency; Humans; Malaria, Falciparum; Membrane Proteins; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2006 |
The costs of changing national policy: lessons from malaria treatment policy guidelines in Tanzania.
Topics: Amodiaquine; Antimalarials; Chloroquine; Clinical Protocols; Drug Combinations; Health Care Costs; Health Education; Health Personnel; Health Policy; Humans; Malaria, Falciparum; Practice Guidelines as Topic; Pyrimethamine; Sulfadoxine; Tanzania | 2006 |
Prevention of malaria during pregnancy in West Africa: policy change and the power of subregional action.
Topics: Africa, Western; Antimalarials; Chloroquine; Communication Barriers; Drug Combinations; Drug Resistance; Evidence-Based Medicine; Female; Financing, Organized; Health Education; Health Policy; Humans; International Cooperation; Interprofessional Relations; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2006 |
A steep decline of malaria morbidity and mortality trends in Eritrea between 2000 and 2004: the effect of combination of control methods.
Topics: Adult; Antimalarials; Bedding and Linens; Child; Chloroquine; DDT; Drug Combinations; Drug Resistance; Eritrea; Female; Humans; Insecticides; Malaria; Malathion; Male; Mosquito Control; National Health Programs; Public Health; Pyrimethamine; Sulfadoxine; Time Factors | 2006 |
The efficacy of sulfadoxine-pyrimethamine alone and in combination with chloroquine for malaria treatment in rural Eastern Sudan: the interrelation between resistance, age and gametocytogenesis.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Child; Chloroquine; Cohort Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Gametogenesis; Humans; Malaria, Falciparum; Male; Parasitemia; Pyrimethamine; Rural Health; Sudan; Sulfadoxine; Treatment Failure; Treatment Outcome | 2006 |
Short report: Dynamics of Plasmodium falciparum malaria after sub-optimal therapy in Uganda.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Disease-Free Survival; DNA, Protozoan; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Medically Underserved Area; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Sulfadoxine; Uganda | 2006 |
Field-based evidence for linkage of mutations associated with chloroquine (pfcrt/pfmdr1) and sulfadoxine-pyrimethamine (pfdhfr/pfdhps) resistance and for the fitness cost of multiple mutations in P. falciparum.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2007 |
Adherence of community caretakers of children to pre-packaged antimalarial medicines (HOMAPAK) among internally displaced people in Gulu district, Uganda.
Topics: Adult; Antimalarials; Caregivers; Child, Preschool; Chloroquine; Drug Combinations; Drug Packaging; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Patient Compliance; Pyrimethamine; Refugees; Sulfadoxine; Surveys and Questionnaires; Uganda | 2006 |
In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum.
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Erythrocytes; Heterocyclic Compounds, 1-Ring; Molecular Structure; Peroxides; Plasmodium falciparum; Pyrimethamine; Spiro Compounds | 2006 |
In vitro study assessing the response of plasmodium falciparum malaria to chloroquine, sulfadoxine/pyrimethamine, quinine and mefloquine in Wad Medani District, Sudan.
Topics: Animals; Antimalarials; Chloroquine; In Vitro Techniques; Mefloquine; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sudan; Sulfadoxine | 2006 |
Impact of chloroquine on viral load in breast milk.
Topics: Adult; Anti-HIV Agents; Antimalarials; Breast Feeding; CD4 Lymphocyte Count; Chloroquine; Drug Combinations; Female; HIV Infections; Humans; Malaria; Milk, Human; Pyrimethamine; RNA, Viral; Sulfadoxine; Viral Load; Zambia | 2006 |
Therapeutic efficacy of sulphadoxine-pyrimethamine and chloroquine for the treatment of uncomplicated malaria in pregnancy in Burkina Faso.
Topics: Adolescent; Adult; Burkina Faso; Chloroquine; Contraindications; Drug Combinations; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2006 |
High prevalence of drug-resistance mutations in Plasmodium falciparum and Plasmodium vivax in southern Ethiopia.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Ethiopia; Female; Humans; Infant; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Mutation; Plasmodium falciparum; Plasmodium vivax; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2006 |
[The microfluorimetric assay (MFA) in in vitro testing the sensitivity of Plasmodium falciparum to antimalarial drugs].
Topics: Animals; Antimalarials; Artemether; Artemisinins; Chloroquine; Cytophotometry; Inhibitory Concentration 50; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Reproducibility of Results | 2006 |
From chloroquine to artemisinin-based combination therapy: the Sudanese experience.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria, Falciparum; Product Surveillance, Postmarketing; Pyrimethamine; Sesquiterpenes; Sudan; Sulfadoxine; Time Factors | 2006 |
[Knowledge and practice among health workers from the Thiès region with regard to new malaria treatment policies].
Topics: Amodiaquine; Antimalarials; Chloroquine; Clinical Competence; Community Health Services; Drug Combinations; Drug Resistance; Education, Nursing; Guideline Adherence; Health Personnel; Health Policy; Health Promotion; Humans; Malaria, Falciparum; Patient Education as Topic; Practice Guidelines as Topic; Pyrimethamine; Rural Health Services; Senegal; Sulfadoxine; Workforce | 2006 |
Methodological issues in the assessment of antimalarial drug treatment: analysis of 13 studies in eight African countries from 2001 to 2004.
Topics: Africa; Amodiaquine; Antimalarials; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Combinations; Female; Genotype; Humans; Infant; Malaria; Male; Pyrimethamine; Reverse Transcriptase Polymerase Chain Reaction; Risk; Sulfadoxine; Treatment Outcome | 2006 |
Physical linkage to drug resistance genes results in conservation of var genes among West Pacific Plasmodium falciparum isolates.
Topics: Amino Acid Sequence; Animals; Antimalarials; Asia, Southeastern; Chloroquine; Chromosome Mapping; Conserved Sequence; Drug Resistance; Electrophoresis, Gel, Pulsed-Field; Genetic Linkage; Humans; Pacific Islands; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine | 2006 |
Relationship between antipyretic effects and cytokine levels in uncomplicated falciparum malaria during different treatment regimes.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antimalarials; Child, Preschool; Chloroquine; Cytokines; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Fever; Humans; Infant; Malaria, Falciparum; Parasitemia; Plasmodium falciparum; Pyrimethamine; Statistics, Nonparametric; Sulfadoxine; Tanzania | 2006 |
Molecular epidemiology of malaria in Cameroon. XXI. Baseline therapeutic efficacy of chloroquine, amodiaquine, and sulfadoxine-pyrimethamine monotherapies in children before national drug policy change.
Topics: Amodiaquine; Antimalarials; Cameroon; Child; Chloroquine; Drug Combinations; Health Policy; Humans; Malaria, Falciparum; Molecular Epidemiology; Pyrimethamine; Sulfadoxine | 2006 |
[In vivo sensitivity of Plasmodium faciparum to chloroquine and sulfadoxine pyrimethamine in the Bobo Dioulasso region (1998-2001): risk factors associated with treatments failures to the two drugs].
Topics: Adolescent; Animals; Antimalarials; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Combinations; Humans; Infant; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Risk Factors; Sulfadoxine; Treatment Failure | 2006 |
A modified Plasmodium falciparum growth inhibition assay (GIA) to assess activity of plasma from malaria endemic areas.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Chloroquine; Dialysis; Dose-Response Relationship, Immunologic; Drug Resistance; Humans; L-Lactate Dehydrogenase; Plasmodium falciparum; Pyrimethamine | 2007 |
Therapeutic efficacy of quinine plus sulfadoxine-pyremethamine for the treatment of uncomplicated falciparum malaria in Bangladesh.
Topics: Adolescent; Adult; Animals; Antimalarials; Bangladesh; Chloroquine; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Failure | 2006 |
Malaria. Chloroquine makes a comeback.
Topics: Adult; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Malawi; Plasmodium; Pyrimethamine; Sulfadoxine | 2006 |
Practical HPLC methods for the quantitative determination of common antimalarials in Africa.
Topics: Africa; Amodiaquine; Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Humans; Pyrimethamine; Reproducibility of Results; Sulfadoxine | 2007 |
Decreased availability of antimalarials in the private sector following the policy change from chloroquine to sulphadoxine-pyrimethamine in the Kilombero Valley, Tanzania.
Topics: Analgesics, Non-Narcotic; Antimalarials; Chloroquine; Drug Combinations; Health Policy; Humans; Malaria, Falciparum; Pharmacies; Pyrimethamine; Sulfadoxine; Tanzania | 2006 |
A multiplex ligase detection reaction-fluorescent microsphere assay for simultaneous detection of single nucleotide polymorphisms associated with Plasmodium falciparum drug resistance.
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Fluorescence; Humans; Ligases; Malaria, Falciparum; Membrane Transport Proteins; Microspheres; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Treating malaria at home in Uganda.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Caregivers; Chloroquine; Developing Countries; Diagnostic Errors; Drug Combinations; Drug Resistance, Viral; Ethanolamines; Fluorenes; Health Services Accessibility; Home Nursing; Humans; Malaria; Measles; Pyrimethamine; Sulfadoxine; Uganda | 2006 |
Consumers stated and revealed preferences for community health workers and other strategies for the provision of timely and appropriate treatment of malaria in southeast Nigeria.
Topics: Adult; Animals; Antimalarials; Chloroquine; Community Health Services; Community Health Workers; Consumer Behavior; Drug Combinations; Female; Health Care Surveys; Humans; Malaria, Falciparum; Male; Middle Aged; Nigeria; Patient Satisfaction; Plasmodium falciparum; Pyrimethamine; Rural Population; Sulfadoxine; Surveys and Questionnaires | 2006 |
Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Genotype; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Microsatellite Repeats; Parasitic Sensitivity Tests; Plasmodium falciparum; Pregnancy; Protozoan Proteins; Pyrimethamine; Retrospective Studies; Senegal; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Immunomodulatory role of chloroquine and pyrimethamine in Plasmodium yoelii 17XL infected mice.
Topics: Animals; Apoptosis; Chloroquine; Cytokines; Immunologic Factors; Malaria; Mice; Mice, Inbred BALB C; Plasmodium yoelii; Pyrimethamine; Reactive Oxygen Species; RNA, Messenger | 2007 |
Home-based management of fever in rural Uganda: community perceptions and provider opinions.
Topics: Adolescent; Adult; Antimalarials; Child, Preschool; Chloroquine; Community Health Services; Community Health Workers; Drug Combinations; Female; Fever; Focus Groups; Health Knowledge, Attitudes, Practice; Home Nursing; Humans; Infant; Malaria; Mother-Child Relations; Public Opinion; Pyrimethamine; Self Administration; Sulfadoxine; Uganda | 2007 |
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
Topics: Acute Disease; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Drug Combinations; Drug Therapy, Combination; Gametogenesis; Histamine H1 Antagonists; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors; Treatment Outcome | 2006 |
Sustained use of insecticide-treated curtains is not associated with greater circulation of drug-resistant malaria parasites, or with higher risk of treatment failure among children with uncomplicated malaria in Burkina Faso.
Topics: Animals; Antimalarials; Bedding and Linens; Burkina Faso; Child, Preschool; Chloroquine; Cross-Sectional Studies; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Infant; Insect Vectors; Insecticides; Malaria, Falciparum; Membrane Transport Proteins; Mosquito Control; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Rural Population; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
The role of communication between clients and health care providers: implications for adherence to malaria treatment in rural Gambia.
Topics: Antimalarials; Attitude to Health; Child; Child, Preschool; Chloroquine; Communication Barriers; Drug Administration Schedule; Drug Combinations; Female; Fever; Gambia; Humans; Infant; Malaria; Male; Patient Compliance; Professional-Patient Relations; Pyrimethamine; Rural Health; Sulfadoxine | 2007 |
Quality evaluation of chloroquine, quinine, sulfadoxine-pyrimethamine and proguanil formulations sold on the market in East Congo DR.
Topics: Antimalarials; Chloroquine; Chromatography, High Pressure Liquid; Democratic Republic of the Congo; Drug Approval; Drug Combinations; Drug Industry; Pharmaceutical Preparations; Product Surveillance, Postmarketing; Proguanil; Pyrimethamine; Quality Control; Quinine; Sulfadoxine; Tablets | 2007 |
Diagnosis and treatment of malaria in peripheral health facilities in Uganda: findings from an area of low transmission in south-western Uganda.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Animals; Child; Child, Preschool; Chloroquine; Drug Combinations; Endemic Diseases; Female; Humans; Infant; Longitudinal Studies; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sensitivity and Specificity; Sulfadoxine; Uganda | 2007 |
Assessing malaria burden during pregnancy in Mali.
Topics: Adult; Animals; Antimalarials; Chloroquine; Cross-Sectional Studies; Drug Combinations; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; Malaria; Mali; Parasitemia; Placenta; Plasmodium; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Pyrimethamine; Sulfadoxine | 2007 |
Molecular surveillance for drug-resistant Plasmodiumfalciparum malaria in Malawi.
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Malawi; Membrane Transport Proteins; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
High prevalence of molecular markers for resistance to chloroquine and pyrimethamine in Plasmodium falciparum from Zimbabwe.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Zimbabwe | 2007 |
Detection of drug resistance markers for chloroquine and pyrimethamine-sulfadoxine in Jazan area, Saudi Arabia using PCR and restriction digestion.
Topics: Animals; Antimalarials; Biomarkers; Chloroquine; Codon; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Saudi Arabia; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs).
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Therapy; Drug Therapy, Combination; Humans; Malaria; Malawi; Pyrimethamine; Rwanda; Senegal; Sulfadoxine; Tanzania; Zimbabwe | 2007 |
Battling the malaria iceberg with chloroquine in India.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Delivery of Health Care; Drug Combinations; Drug Resistance; Humans; India; Malaria; Preventive Health Services; Pyrimethamine; Sesquiterpenes; Socioeconomic Factors; Sulfadoxine; Time Factors | 2007 |
The implication of dihydrofolate reductase and dihydropteroate synthetase gene mutations in modification of Plasmodium falciparum characteristics.
Topics: Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Therapy, Combination; Gene Frequency; Genes, Protozoan; Humans; Malaria, Falciparum; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Global Health; Half-Life; Humans; Lumefantrine; Malaria; Mefloquine; Pregnancy; Pregnancy Complications, Infectious; Proguanil; Pyrimethamine; Quinine; Sesquiterpenes; Sulfadoxine | 2007 |
Health workers perceptions on chloroquine and sulfadoxine/sulfalene pyrimethamine monotherapies: implications for the change to combination therapy of artemether/lumefantrine in Tanzania.
Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Attitude of Health Personnel; Chloroquine; Clinical Competence; Cross-Sectional Studies; Drug Combinations; Drug Therapy, Combination; Ethanolamines; Female; Fluorenes; Guideline Adherence; Health Policy; Humans; Interviews as Topic; Malaria; Male; Middle Aged; Pyrimethamine; Sulfadoxine; Tanzania; Urban Health | 2007 |
Extensive genetic diversity in the Plasmodium falciparum Na+/H+ exchanger 1 transporter protein implicated in quinine resistance.
Topics: Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Gene Frequency; Genetic Variation; Genotype; Geography; India; Molecular Sequence Data; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Quinine; Sequence Homology, Amino Acid; Sodium-Potassium-Chloride Symporters; Sulfadoxine | 2007 |
Prevalence of mutations associated with antimalarial drugs in Plasmodium falciparum isolates prior to the introduction of sulphadoxine-pyrimethamine as first-line treatment in Iran.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Endemic Diseases; Humans; Infant; Iran; Malaria, Falciparum; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Prevalence; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2007 |
Drug-resistant malaria parasites introduced into Madagascar from Comoros Islands.
Topics: Adult; Animals; Antimalarials; Child, Preschool; Chloroquine; Comoros; Drug Resistance, Multiple; Female; Humans; Madagascar; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Pyrimethamine; Travel | 2007 |
A simple technique for the detection of anti-malarial drug formulations and their presence in human urine.
Topics: Amodiaquine; Antimalarials; Biological Assay; Biological Availability; Chloroquine; Chromatography, Thin Layer; Fraud; Humans; Malaria; Primaquine; Product Surveillance, Postmarketing; Pyrimethamine; Quality Control; Quinine; Sulfadoxine | 2006 |
Pharmacokinetic determinants of the window of selection for antimalarial drug resistance.
Topics: Algorithms; Amodiaquine; Animals; Antimalarials; Artemisinins; Chloroquine; Computer Simulation; Drug Resistance; Malaria; Mefloquine; Models, Theoretical; Pyrimethamine; Quinine | 2008 |
Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment.
Topics: Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Chlorpheniramine; Clinical Protocols; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Infant; Malaria, Falciparum; Male; Nigeria; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2008 |
High frequency of Plasmodium falciparum CICNI/SGEAA and CVIET haplotypes without association with resistance to sulfadoxine/pyrimethamine and chloroquine combination in the Daraweesh area, in Sudan.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Mutation; Plasmodium falciparum; Pyrimethamine; Sudan; Sulfadoxine | 2008 |
[Plasmodium falciparum chloroquine and pyrimethamine resistance monitoring network with molecular tools in the Niger River valley, Republic of Niger].
Topics: Animals; Antigens, Protozoan; Antimalarials; Asparagine; Biomarkers; Chloroquine; Communicable Disease Control; Drug Resistance; Humans; Lysine; Membrane Transport Proteins; Mutation; Niger; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Serine; Tetrahydrofolate Dehydrogenase; Threonine | 2008 |
Assessment of the therapeutic efficacy of chloroquine in the treatment of uncomplicated Plasmodium falciparum malaria in a tribal block of the Kalahandi district of Orissa, India.
Topics: Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Prevalence; Pyrimethamine; Rural Health; Sulfadoxine; Treatment Failure | 2008 |
Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives.
Topics: Animals; Antimalarials; Antiprotozoal Agents; Chloroquine; Drug Resistance; Leishmania donovani; Oxazines; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2008 |
[Self-medication in the treatment of acute malaria: study based on users of private health drug stores in Ouagadougou, Burkina Faso].
Topics: Acute Disease; Adult; Antimalarials; Artemisinins; Burkina Faso; Child; Chloroquine; Cross-Sectional Studies; Drug Administration Schedule; Drug Combinations; Drug Resistance; Drug Utilization; Educational Status; Female; Health Knowledge, Attitudes, Practice; Humans; Malaria, Falciparum; Male; Middle Aged; Motivation; Pharmacies; Pyrimethamine; Self Medication; Sulfadoxine; Urban Population | 2008 |
Diminished Plasmodium falciparum sensitivity to quinine exposure in vitro and in a sequential multi-drug regimen: A preliminary investigation in Guyana, South America.
Topics: Animals; Antimalarials; Child; Chloroquine; Doxycycline; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Guyana; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Quinine; Sulfadoxine; Treatment Outcome; Young Adult | 2008 |
Antimalarial drug use in general populations of tropical Africa.
Topics: Age Factors; Animals; Antibodies, Protozoan; Antimalarials; Burkina Faso; Cameroon; Child; Child, Preschool; Chloroquine; Chromatography, High Pressure Liquid; Drug Resistance; Female; Fever of Unknown Origin; Geography; Humans; Male; Pyrimethamine; Selection, Genetic; Senegal; Socioeconomic Factors; Surveys and Questionnaires; Urine | 2008 |
Molecular epidemiology of drug-resistant malaria in western Kenya highlands.
Topics: Adolescent; Animals; Antimalarials; Child; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Genotype; Humans; Kenya; Malaria, Falciparum; Membrane Transport Proteins; Molecular Epidemiology; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2008 |
Predictors of antimalarial treatment failure in an area of unstable malaria transmission in eastern Sudan.
Topics: Adolescent; Age Factors; Antimalarials; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Female; Humans; Infant; Malaria, Falciparum; Male; Parasitemia; Predictive Value of Tests; Pyrimethamine; Risk Factors; Sudan; Sulfadoxine; Treatment Failure | 2009 |
[Is the antimalarial fight effective in Mayotte?].
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Comoros; Drug Combinations; Female; Humans; Incidence; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2008 |
Genetic evidence for Plasmodium falciparum resistance to chloroquine and pyrimethamine in Indochina and the Western Pacific between 1984 and 1998.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Genotype; Membrane Transport Proteins; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Time Factors | 2008 |
Antiplasmodial activity of root extract and fractions of Croton zambesicus.
Topics: Animals; Antimalarials; Chloroquine; Croton; Female; Lethal Dose 50; Malaria; Male; Mice; Parasitemia; Phytotherapy; Plant Extracts; Plant Roots; Plasmodium berghei; Pyrimethamine | 2009 |
Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola.
Topics: Adolescent; Angola; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2008 |
Poor knowledge on new malaria treatment guidelines among drug dispensers in private pharmacies in Tanzania: the need for involving the private sector in policy preparations and implementation.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Cross-Sectional Studies; Decision Making; Drug Combinations; Ethanolamines; Fluorenes; Health Care Surveys; Health Knowledge, Attitudes, Practice; Health Policy; Humans; Interviews as Topic; Malaria; Medication Systems; Pharmacies; Practice Guidelines as Topic; Private Sector; Pyrimethamine; Sulfadoxine; Surveys and Questionnaires; Tanzania | 2008 |
Perception and practice of malaria prophylaxis in pregnancy among primary health care providers in Ibadan, Nigeria.
Topics: Adolescent; Adult; Antimalarials; Awareness; Chloroquine; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, Practice; Health Status Indicators; Health Surveys; Humans; Malaria; Middle Aged; Nigeria; Physicians, Family; Practice Patterns, Physicians'; Pregnancy; Prenatal Care; Primary Health Care; Pyrimethamine; Social Perception; Surveys and Questionnaires; Young Adult | 2008 |
Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Infant; Malaria; Male; Pyrimethamine; Somalia; Sulfadoxine; Treatment Outcome | 2009 |
Prevalence of polymorphisms in DHFR, DHPS, PFMDR1 and PFCRT genes of Plasmodium falciparum isolates in Quang Tri Province, Vietnam.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Female; Humans; Male; Middle Aged; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Vietnam; Young Adult | 2008 |
The evolution of drug-resistant malaria.
Topics: Africa; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Evolution, Molecular; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2009 |
Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women.
Topics: Adult; Animals; Antigens, Protozoan; Antimalarials; Chloroquine; Drug Combinations; Female; Genotype; Humans; Malaria, Falciparum; Merozoite Surface Protein 1; Mozambique; Parasitemia; Plasmodium falciparum; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Protozoan Proteins; Pyrimethamine; Recurrence; Sensitivity and Specificity; Sulfadoxine | 2009 |
Malaria - change in therapeutic policy.
Topics: Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2009 |
[Change of antimalarial first-line treatment in Burkina Faso in 2005].
Topics: Animals; Antimalarials; Burkina Faso; Child, Preschool; Chloroquine; Female; Health Policy; Hemoglobins; Humans; Infant; Malaria; Plasmodium; Pregnancy; Pregnancy Complications; Pyrimethamine; Sulfadoxine; Treatment Failure; Treatment Outcome | 2009 |
Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria.
Topics: Africa; Alleles; Animals; Antimalarials; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Phylogeny; Plasmodium falciparum; Polymorphism, Single Nucleotide; Population Surveillance; Protozoan Proteins; Pyrimethamine; Selection, Genetic; Sulfadoxine | 2009 |
Genetic structure of Plasmodium falciparum populations between lowland and highland sites and antimalarial drug resistance in Western Kenya.
Topics: Adolescent; Animals; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Endemic Diseases; Genetics, Population; Haplotypes; Humans; Kenya; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Travel | 2009 |
Novel pfdhps haplotypes among imported cases of Plasmodium falciparum malaria in the United Kingdom.
Topics: Adult; Alleles; Amino Acid Sequence; Animals; Antimalarials; Atovaquone; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Folic Acid Antagonists; Haplotypes; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Proguanil; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; United Kingdom | 2009 |
Chloroquine resistance before and after its withdrawal in Kenya.
Topics: Animals; Antimalarials; Chloroquine; Drug Approval; Drug Combinations; Drug Resistance; Genotype; Humans; Kenya; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Restriction Mapping; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Time Factors | 2009 |
Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area.
Topics: Animals; Antimalarials; Brazil; Chloroquine; Drug Combinations; Drug Resistance; Endemic Diseases; Haplotypes; Humans; Malaria, Falciparum; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine | 2009 |
Plasmodium falciparum drug resistance in Madagascar: facing the spread of unusual pfdhfr and pfmdr-1 haplotypes and the decrease of dihydroartemisinin susceptibility.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Haplotypes; Madagascar; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2009 |
Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia.
Topics: Animals; Antimalarials; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Gene Frequency; Humans; Indonesia; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Seasons; Sulfadoxine | 2009 |
Pharmacokinetic properties of azithromycin in pregnancy.
Topics: Adult; Antimalarials; Area Under Curve; Azithromycin; Chloroquine; Chromatography, High Pressure Liquid; Drug Combinations; Female; Half-Life; Humans; Intestinal Absorption; Models, Statistical; Papua New Guinea; Pregnancy; Pyrimethamine; Sulfadoxine; Tandem Mass Spectrometry; Young Adult | 2010 |
Evidence of selective sweeps in genes conferring resistance to chloroquine and pyrimethamine in Plasmodium falciparum isolates in India.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Genes, Protozoan; Genotype; Humans; India; Malaria, Cerebral; Malaria, Falciparum; Microsatellite Repeats; Parasitic Sensitivity Tests; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sequence Analysis, DNA | 2010 |
Plasmodium falciparum resistance to anti-malarial drugs in Papua New Guinea: evaluation of a community-based approach for the molecular monitoring of resistance.
Topics: Adolescent; Aged; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Papua New Guinea; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Failure; Young Adult | 2010 |
Markers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolates.
Topics: Alleles; Amplified Fragment Length Polymorphism Analysis; Animals; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Eswatini; Genotype; Humans; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Plasmodium falciparum; Pyrimethamine; Retrospective Studies; Sequence Analysis, DNA; Sulfadoxine | 2010 |
Active case detection, treatment of falciparum malaria with combined chloroquine and sulphadoxine/pyrimethamine and vivax malaria with chloroquine and molecular markers of anti-malarial resistance in the Republic of Vanuatu.
Topics: Adolescent; Adult; Antigens, Protozoan; Antimalarials; Case-Control Studies; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Genetic Markers; Humans; Incidence; Malaria, Falciparum; Malaria, Vivax; Male; Membrane Transport Proteins; Middle Aged; Parasitemia; Plasmodium falciparum; Plasmodium vivax; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Outcome; Vanuatu; Young Adult | 2010 |
Stress, drugs and the evolution of reproductive restraint in malaria parasites.
Topics: Animals; Antimalarials; Biological Evolution; Chloroquine; Drug Resistance; Host-Parasite Interactions; Humans; Plasmodium falciparum; Pyrimethamine; Reproduction, Asexual; Stress, Physiological | 2010 |
Perception and practice of malaria prophylaxis in pregnancy among health care providers in Ibadan.
Topics: Antimalarials; Chloroquine; Community Health Services; Drug Combinations; Female; Guideline Adherence; Health Facilities; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Interviews as Topic; Malaria; Nigeria; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Parasitic; Prescriptions; Program Evaluation; Pyrimethamine; Sulfadoxine | 2007 |
Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication.
Topics: Antimalarials; Antiviral Agents; Artemisinins; Cells, Cultured; Chloroquine; Enzyme-Linked Immunosorbent Assay; HIV Core Protein p24; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocytes; Pyrimethamine; Virus Replication | 2010 |
Plasmodium berghei K173: selection of resistance to naphthoquine in a mouse model.
Topics: Animals; Antimalarials; Artemisinins; Chloroquine; Dose-Response Relationship, Drug; Drug Resistance; Ethanolamines; Fluorenes; Lumefantrine; Malaria; Male; Mice; Naphthoquinones; Plasmodium berghei; Pyrimethamine; Random Allocation | 2011 |
Monitoring of malaria parasite resistance to chloroquine and sulphadoxine-pyrimethamine in the Solomon Islands by DNA microarray technology.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Female; Gene Frequency; Haplotypes; Humans; Infant; Malaria, Falciparum; Male; Melanesia; Middle Aged; Mutation, Missense; Oligonucleotide Array Sequence Analysis; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Young Adult | 2010 |
Increased prevalence of the pfdhfr/phdhps quintuple mutant and rapid emergence of pfdhps resistance mutations at codons 581 and 613 in Kisumu, Kenya.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Chloroquine; Codon; Cross-Sectional Studies; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Ethanolamines; Fluorenes; Folic Acid Antagonists; Genotype; Humans; Inhibitory Concentration 50; Kenya; Malaria; Mutation, Missense; Parasitic Sensitivity Tests; Plasmodium; Prevalence; Protozoan Proteins; Pyrimethamine; Quinolones; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2010 |
Incorporation of basic side chains into cryptolepine scaffold: structure-antimalarial activity relationships and mechanistic studies.
Topics: Animals; Antimalarials; Cell Line, Tumor; Chlorocebus aethiops; Chloroquine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA; Drug Resistance; Erythrocytes; Hemin; Humans; Indole Alkaloids; Mefloquine; Oligonucleotides; Plasmodium falciparum; Pyrimethamine; Quinolines; Structure-Activity Relationship; Vero Cells | 2011 |
Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Female; Gene Dosage; Genes, Protozoan; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Pakistan; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2011 |
Selective sweeps and genetic lineages of Plasmodium falciparum drug -resistant alleles in Ghana.
Topics: Alleles; Amino Acid Substitution; Antimalarials; Biological Evolution; Child, Preschool; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Evolution, Molecular; Genotype; Ghana; Humans; Infant; Infant, Newborn; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Mutation, Missense; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2011 |
Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Malaria, Vivax; Nepal; Plasmodium falciparum; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2011 |
Combining community case management and intermittent preventive treatment for malaria.
Topics: Africa; Antimalarials; Case Management; Child; Child, Preschool; Chloroquine; Community Health Services; Community Health Workers; Drug Combinations; Female; Humans; Incidence; Infant; Malaria; Pregnancy; Preventive Health Services; Pyrimethamine; Seasons; Sulfadoxine | 2011 |
[Comparison of efficacy of chloroquine versus sulfadoxine-pyrimethamine in malaria prevention in pregnant women in the Toamasina region (Madagascar)].
Topics: Adolescent; Adult; Antimalarials; Chloroquine; Drug Combinations; Endemic Diseases; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Madagascar; Malaria; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimethamine; Sulfadoxine | 2011 |
Utilisation of malaria preventive measures during pregnancy and birth outcomes in Ibadan, Nigeria.
Topics: Adult; Animals; Antimalarials; Attitude to Health; Chloroquine; Drug Combinations; Female; Health Promotion; Humans; Malaria; Maternal Health Services; Maternal Welfare; Mosquito Control; Nigeria; Patient Acceptance of Health Care; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Risk Factors; Sulfadoxine; Young Adult | 2011 |
Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Genetic Markers; Humans; Infant; Malaria, Falciparum; Membrane Transport Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Yemen; Young Adult | 2011 |
Plasmodium falciparum: differential selection of drug resistance alleles in contiguous urban and peri-urban areas of Brazzaville, Republic of Congo.
Topics: Adolescent; Alleles; Animals; Anopheles; Antimalarials; Chloroquine; Congo; Drug Resistance; Female; Gene Frequency; Genetic Variation; Haplotypes; Humans; Insect Vectors; Malaria, Falciparum; Male; Membrane Transport Proteins; Merozoite Surface Protein 1; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Selection, Genetic; Tetrahydrofolate Dehydrogenase; Urbanization; Young Adult | 2011 |
Prolonged elevation of viral loads in HIV-1-infected children in a region of intense malaria transmission in Northern Uganda: a prospective cohort study.
Topics: Antimalarials; CD4 Lymphocyte Count; Child; Child, Preschool; Chloroquine; Disease Progression; Drug Combinations; Female; Follow-Up Studies; HIV Infections; HIV-1; Humans; Incidence; Infant; Malaria, Falciparum; Male; Parasitemia; Plasmodium falciparum; Prospective Studies; Pyrimethamine; RNA, Viral; Sulfadoxine; Treatment Outcome; Uganda; Viral Load | 2010 |
Molecular markers of Plasmodium falciparum drug resistance in southern highland Rwanda.
Topics: Antimalarials; Child, Preschool; Chloroquine; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Female; Gene Frequency; Genotype; Humans; Infant; Malaria, Falciparum; Male; Mutation, Missense; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Rwanda | 2012 |
Molecular assessment of dhfr/dhps mutations among Plasmodium vivax clinical isolates after introduction of sulfadoxine/pyrimethamine in combination with artesunate in Iran.
Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Haplotypes; Humans; Infant; Iran; Malaria, Vivax; Middle Aged; Mutation; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult | 2012 |
Identification of pyrimethamine- and chloroquine-resistant Plasmodium falciparum in Africa between 1984 and 1998: genotyping of archive blood samples.
Topics: Africa; Antimalarials; Chloroquine; DNA, Protozoan; Drug Resistance; Genotype; Genotyping Techniques; Humans; Malaria, Falciparum; Membrane Transport Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine | 2011 |
Mosquito infection studies with Aotus monkeys and humans infected with the Chesson strain of Plasmodiun vivax.
Topics: Animals; Anopheles; Antimalarials; Aotidae; Chloroquine; Disease Management; Disease Models, Animal; Host-Parasite Interactions; Humans; Malaria; Male; Monkey Diseases; Plasmodium vivax; Primaquine; Proguanil; Pyrimethamine; Quinine | 2012 |
Antibodies to malaria vaccine candidates are associated with chloroquine or sulphadoxine/pyrimethamine treatment efficacy in children in an endemic area of Burkina Faso.
Topics: Adolescent; Antibodies, Protozoan; Antimalarials; Biomarkers; Burkina Faso; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Therapy, Combination; Female; Humans; Immunoglobulin G; Infant; Malaria Vaccines; Malaria, Falciparum; Male; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2012 |
Patterns of case management and chemoprevention for malaria-in-pregnancy by public and private sector health providers in Enugu state, Nigeria.
Topics: Adult; Antimalarials; Case Management; Chemoprevention; Chloroquine; Drug Combinations; Female; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Infant, Newborn; Malaria; Nigeria; Outcome Assessment, Health Care; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Parasitic; Private Sector; Public Sector; Pyrimethamine; Sulfadoxine; Surveys and Questionnaires | 2012 |
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Humans; Infant; Male; Mefloquine; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Phenanthrenes; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Saudi Arabia; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult | 2012 |
Prevalence of molecular markers of Plasmodium falciparum drug resistance in Dakar, Senegal.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Female; Gene Dosage; Gene Frequency; Genes, Protozoan; Hospitals, Military; Humans; Malaria, Falciparum; Male; Mutation, Missense; Plasmodium falciparum; Point Mutation; Prevalence; Pyrimethamine; Senegal; Sulfadoxine | 2012 |
The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Malaria; Male; Methylene Blue; Mice; Plasmodium berghei; Pyrimethamine; Quinine | 2012 |
Monitoring antimalarial drug resistance in India via sentinel sites: outcomes and risk factors for treatment failure, 2009-2010.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Resistance, Microbial; Humans; India; Kaplan-Meier Estimate; Malaria, Falciparum; Malaria, Vivax; Pyrimethamine; Risk Factors; Sulfadoxine; Treatment Outcome | 2012 |
Molecular monitoring of antimalarial drug resistance among Plasmodium falciparum field isolates from Odisha, India.
Topics: Antimalarials; Artemisinins; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; India; Malaria, Falciparum; Mutation, Missense; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2013 |
Prevalence of the molecular marker of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in Benin seven years after the change of malaria treatment policy.
Topics: Adolescent; Antimalarials; Benin; Blood; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Female; Genetic Markers; Humans; Infant; Malaria, Falciparum; Male; Mutation Rate; Plasmodium falciparum; Point Mutation; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2013 |
Antimalarial potential of China 30 and Chelidonium 30 in combination therapy against lethal rodent malaria parasite: Plasmodium berghei.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chelidonium; Chloroquine; Cinchona; Female; Homeopathy; Malaria; Male; Materia Medica; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Plasmodium berghei; Pyrimethamine | 2013 |
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum.
Topics: Amino Acid Sequence; Animals; Antimalarials; Cell Membrane; Chloroquine; Drug Resistance; Erythrocytes; Genetic Complementation Test; HEK293 Cells; Host-Parasite Interactions; Humans; Malaria, Falciparum; Microscopy, Fluorescence; Microscopy, Immunoelectron; Molecular Sequence Data; Morpholines; Mutation; Pantothenic Acid; Phylogeny; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Symporters | 2013 |
In vitro and in vivo antimalarial activity and cytotoxicity of extracts and fractions from the leaves, root-bark and stem-bark of Triclisia gilletii.
Topics: Animals; Antimalarials; Cell Line; Cell Survival; Chloroquine; Drug Resistance, Multiple; Humans; Malaria; Menispermaceae; Mice; Parasitemia; Plant Bark; Plant Extracts; Plant Leaves; Plant Roots; Plasmodium berghei; Plasmodium falciparum; Pyrimethamine | 2013 |
[Prevalence of Plasmodium falciparum, anemia and molecular markers of chloroquine and sulfadoxine-pyriméthamine resistance in delivered women in Fana, Mali].
Topics: Adolescent; Adult; Anemia; Chloroquine; Delivery, Obstetric; Drug Combinations; Drug Resistance; Female; Genetic Markers; Humans; Malaria, Falciparum; Mali; Plasmodium falciparum; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Pyrimethamine; Sulfadoxine; Young Adult | 2013 |
Structure-activity relationship studies of pyrrolone antimalarial agents.
Topics: Animals; Antimalarials; Chloroquine; Drug Resistance; Half-Life; Mice; Microsomes, Liver; Plasmodium falciparum; Pyrimethamine; Pyrroles; Structure-Activity Relationship | 2013 |
Treatment of pregnant BALB/c mice with sulphadoxine pyrimethamine or chloroquine abrogates Plasmodium berghei induced placental pathology.
Topics: Animals; Antimalarials; Antioxidants; Chloroquine; DNA Fragmentation; Drug Combinations; Female; Lipid Peroxidation; Malaria; Mice; Mice, Inbred BALB C; Parasitemia; Placenta Diseases; Plasmodium berghei; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2014 |
Trends in antimalarial drug use in Africa.
Topics: Africa; Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance; Health Surveys; Humans; Malaria, Falciparum; Models, Statistical; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Time Factors | 2013 |
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Evaluation, Preclinical; Erythrocyte Count; Erythrocyte Transfusion; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Mefloquine; Mice; Mice, Inbred NOD; Mice, SCID; Primaquine; Pyrimethamine; Reproducibility of Results; Sensitivity and Specificity; Transplantation, Heterologous | 2013 |
Low prevalence of the molecular markers of Plasmodium falciparum resistance to chloroquine and sulphadoxine/pyrimethamine in asymptomatic children in Northern Benin.
Topics: Adolescent; Animals; Antimalarials; Benin; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Female; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Male; Plasmodium falciparum; Point Mutation; Polymerase Chain Reaction; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2013 |
Insights following change in drug policy: a descriptive study for antimalarial prescription practices in children of public sector health facilities in Jharkhand state of India.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Cross-Sectional Studies; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Health Facilities; Humans; Inappropriate Prescribing; India; Infant; Malaria; Male; Practice Patterns, Physicians'; Prescriptions; Prospective Studies; Public Sector; Pyrimethamine; Retrospective Studies; Sulfadoxine | 2013 |
Molecular analysis of chloroquine and sulfadoxine-pyrimethamine resistance-associated alleles in Plasmodium falciparum isolates from Nicaragua.
Topics: Alleles; Antimalarials; Chloroquine; Dihydropteroate Synthase; DNA, Protozoan; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Membrane Transport Proteins; Nicaragua; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2014 |
Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Child, Preschool; Chloroquine; Clinical Trials as Topic; Drug Combinations; Drug Resistance; Ethanolamines; Female; Fluorenes; Genetic Markers; Humans; Infant; Malaria, Falciparum; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Time Factors; Uganda | 2014 |
[Mutant alleles associated to chloroquine and sulfadoxine-pyrimethanime resistance in Plasmodium falciparum of the Ecuador-Peru and Ecuador-Colombia borders].
Topics: Alleles; Antimalarials; Chloroquine; Colombia; Drug Combinations; Drug Resistance; Ecuador; Humans; Mutation; Peru; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2014 |
Molecular surveillance of pvdhfr, pvdhps, and pvmdr-1 mutations in Plasmodium vivax isolates from Yunnan and Anhui provinces of China.
Topics: Adult; Antimalarials; Child; Child, Preschool; China; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Epidemiological Monitoring; Haplotypes; Humans; Malaria, Vivax; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium vivax; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2014 |
Molecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapy.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Codon; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Female; Haplotypes; Humans; India; Malaria, Falciparum; Male; Membrane Transport Proteins; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2014 |
Malaria prevention and treatment in pregnancy: survey of current practice among private medical practitioners in Lagos, Nigeria.
Topics: Adult; Antimalarials; Chloroquine; Female; Humans; Malaria; Male; Middle Aged; Nigeria; Practice Patterns, Physicians'; Pregnancy; Pregnancy Complications, Parasitic; Prenatal Care; Pyrimethamine; Surveys and Questionnaires; Women's Health; World Health Organization | 2015 |
Molecular epidemiology and seroprevalence in asymptomatic Plasmodium falciparum infections of Malagasy pregnant women in the highlands.
Topics: Adolescent; Adult; Antibodies, Protozoan; Antimalarials; Asymptomatic Infections; Chloroquine; Drug Combinations; Drug Resistance; Female; Fluorescent Antibody Technique, Indirect; Humans; Madagascar; Malaria; Middle Aged; Molecular Epidemiology; Plasmodium; Pregnancy; Prevalence; Protozoan Proteins; Pyrimethamine; Real-Time Polymerase Chain Reaction; Seroepidemiologic Studies; Sulfadoxine; Young Adult | 2015 |
Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials.
Topics: Amodiaquine; Antimalarials; Atovaquone; Chloroquine; Colorimetry; Heme; Plasmodium falciparum; Pyrimethamine; Trophozoites | 2015 |
Changing Malaria Prevalence on the Kenyan Coast since 1974: Climate, Drugs and Vector Control.
Topics: Adolescent; Adult; Aged; Antimalarials; Bayes Theorem; Child; Child, Preschool; Chloroquine; Climate; Drug Combinations; Drug Resistance; Female; Health Surveys; Humans; Insecticide-Treated Bednets; Kenya; Malaria, Falciparum; Male; Middle Aged; Mosquito Control; Plasmodium falciparum; Prevalence; Pyrimethamine; Rainforest; Retrospective Studies; Sulfadoxine | 2015 |
Comparative Study of Effectiveness and Resistance Profile of Chloroquine and Sulfadoxine-Pyrimethamine in Uncomplicated Plasmodium falciparum Malaria in Kolkata.
Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Drug Combinations; Drug Resistance; Female; Humans; India; Malaria, Falciparum; Male; Middle Aged; Parasite Load; Parasitemia; Pilot Projects; Pyrimethamine; Sulfadoxine; Young Adult | 2015 |
Inhibition of Glutathione Biosynthesis Sensitizes Plasmodium berghei to Antifolates.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Chloroquine; Drug Resistance; Female; Glutamate-Cysteine Ligase; Glutathione; Malaria; Mice; Mice, Inbred BALB C; Plasmodium berghei; Pyrimethamine; Sulfadoxine | 2016 |
Comparative assessment on the prevalence of mutations in the Plasmodium falciparum drug-resistant genes in two different ecotypes of Odisha state, India.
Topics: Alleles; Antimalarials; Chloroquine; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Ecotype; Gene Expression; Haplotypes; Humans; India; Linkage Disequilibrium; Malaria, Falciparum; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2016 |
Antimalarial Activity of Small-Molecule Benzothiazole Hydrazones.
Topics: Animals; Antimalarials; Benzothiazoles; Chloroquine; Drug Resistance, Multiple; Hydrazones; Iron; Male; Mice; Plasmodium falciparum; Plasmodium yoelii; Pyrimethamine | 2016 |
A link between poor quality antimalarials and malaria drug resistance?
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2016 |
Malaria research and its influence on anti-malarial drug policy in Malawi: a case study.
Topics: Antimalarials; Artemether; Artemisinins; Biomedical Research; Chloroquine; Drug Combinations; Drug Resistance; Ethanolamines; Evidence-Based Medicine; Fluorenes; Health Policy; Humans; Lumefantrine; Malaria; Malaria, Falciparum; Malawi; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Treatment Outcome | 2016 |
Molecular markers associated with resistance to commonly used antimalarial drugs among Plasmodium falciparum isolates from a malaria-endemic area in Taiz governorate-Yemen during the transmission season.
Topics: Alleles; Antimalarials; Artemisinins; Artesunate; Chloroquine; Cross-Sectional Studies; Dihydropteroate Synthase; Drug Combinations; Drug Resistance; Genotype; Malaria, Falciparum; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyrimethamine; Sequence Analysis, DNA; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Yemen | 2016 |
Plasmodium falciparum Drug-Resistant Haplotypes and Population Structure in Postearthquake Haiti, 2010.
Topics: Alleles; Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Earthquakes; Genetics, Population; Haiti; Haplotypes; Humans; Malaria, Falciparum; Membrane Transport Proteins; Microsatellite Repeats; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2016 |
Molecular surveillance of Plasmodium falciparum drug resistance markers reveals partial recovery of chloroquine susceptibility but sustained sulfadoxine-pyrimethamine resistance at two sites of different malaria transmission intensities in Rwanda.
Topics: Adolescent; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Genotype; Haplotypes; Humans; Infant; Infant, Newborn; Kenya; Malaria; Malaria, Falciparum; Malawi; Male; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Rwanda; Sulfadoxine; Tanzania; Uganda | 2016 |
Prevalence of Plasmodium falciparum Molecular Markers of Antimalarial Drug Resistance in a Residual Malaria Focus Area in Sabah, Malaysia.
Topics: Adult; Alleles; Antimalarials; Biomarkers; Child; Chloroquine; Drug Combinations; Drug Resistance; Gene Dosage; Humans; Malaria, Falciparum; Malaysia; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2016 |
Plasmodium falciparum Genetic Diversity in Continental Equatorial Guinea before and after Introduction of Artemisinin-Based Combination Therapy.
Topics: Amodiaquine; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Chloroquine; DNA Copy Number Variations; Drug Combinations; Drug Resistance; Equatorial Guinea; Female; Genetic Loci; Genetic Variation; Genotype; Humans; Malaria, Falciparum; Male; Membrane Transport Proteins; Microsatellite Repeats; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2017 |
The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum Drug Resistance, Identification of Species, and Genotyping in a Single Reaction.
Topics: Antimalarials; Artemisinins; Atovaquone; Chloroquine; Drug Resistance; Epidemiological Monitoring; Genotyping Techniques; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Pyrimethamine; Reagent Kits, Diagnostic; Sulfadoxine | 2017 |
Unexpected selections of Plasmodium falciparum polymorphisms in previously treatment-naïve areas after monthly presumptive administration of three different anti-malarial drugs in Liberia 1976-78.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Liberia; Malaria, Falciparum; Plasmodium falciparum; Polymerase Chain Reaction; Polymorphism, Genetic; Proguanil; Protozoan Proteins; Pyrimethamine; Selection, Genetic | 2017 |
Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal.
Topics: Adolescent; Amodiaquine; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genotype; Genotyping Techniques; Humans; Indoles; Inhibitory Concentration 50; Malaria; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Quinolines; Senegal; Young Adult | 2017 |
Nicotinamide inhibits the growth of P. falciparum and enhances the antimalarial effect of artemisinin, chloroquine and pyrimethamine.
Topics: Animals; Antimalarials; Artemisinins; Cell Line; Cell Survival; Chloroquine; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Humans; Life Cycle Stages; Niacinamide; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine | 2017 |
Pooled-DNA sequencing identifies genomic regions of selection in Nigerian isolates of Plasmodium falciparum.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Gene Frequency; Genetic Variation; Haplotypes; Humans; Malaria, Falciparum; Nigeria; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Selection, Genetic; Sequence Analysis, DNA; Sulfadoxine | 2017 |
Optimal antimalarial dose regimens for chloroquine in pregnancy based on population pharmacokinetic modelling.
Topics: Adult; Antimalarials; Chloroquine; Drug Combinations; Female; Humans; Malaria, Falciparum; Metabolic Clearance Rate; Models, Biological; Papua New Guinea; Plasmodium falciparum; Pregnancy; Pyrimethamine; Sulfadoxine | 2017 |
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.
Topics: 2,2'-Dipyridyl; Animals; Antimalarials; Atovaquone; Chloroquine; Drug Design; Female; Humans; Hydrazines; Mice; Mutagenicity Tests; Mutagens; Oxadiazoles; Parasitemia; Plasmodium falciparum; Pyrimethamine; Structure-Activity Relationship | 2017 |
Spatio-temporal distribution of PfMDR1 polymorphism among uncomplicated Plasmodium falciparum malaria cases along international border of north east India.
Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Bangladesh; Chloroquine; Drug Combinations; Drug Resistance; Erythrocytes; Gene Expression; Haplotypes; Humans; India; Lumefantrine; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Myanmar; Phylogeny; Phylogeography; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Sulfadoxine | 2018 |
Molecular evaluation of pvdhfr and pvmdr-1 mutants in Plasmodium vivax isolates after treatment with sulfadoxine/pyrimethamine and chloroquine in Iran during 2001-2016.
Topics: Amino Acid Substitution; Chloroquine; Codon; Drug Therapy, Combination; Gene Frequency; Genotype; History, 21st Century; Humans; Iran; Malaria, Vivax; Multidrug Resistance-Associated Proteins; Mutation; Plasmodium vivax; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Protozoan Proteins; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2018 |
Monocyte phagocytosis of malaria β-haematin in the presence of artemisinin, amodiaquine, chloroquine, doxycycline, primaquine, pyrimethamine and quinine.
Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Cell Count; Cell Line; Chloroquine; Doxycycline; Electron Probe Microanalysis; Heme; Hemeproteins; Humans; Leukocytes, Mononuclear; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Monocytes; Peroxidase; Phagocytosis; Primaquine; Pyrimethamine; Quinine; Spectrophotometry; Temperature; U937 Cells | 2019 |
An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated gene.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Gene Deletion; Gene Duplication; Genome; Genome-Wide Association Study; Genotype; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Sulfadoxine; Tetrahydrofolate Dehydrogenase | 2019 |
Evolution of Plasmodium falciparum drug resistance genes following artemisinin combination therapy in Sudan.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; DNA, Protozoan; Drug Resistance; Drug Therapy, Combination; Genetic Markers; Genotype; Humans; Lumefantrine; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Pyrimethamine; Sudan; Sulfadoxine | 2019 |
The changing landscape of Plasmodium falciparum drug resistance in the Democratic Republic of Congo.
Topics: Adolescent; Adult; Alcohol Dehydrogenase; Antimalarials; Chloroquine; Cross-Sectional Studies; Democratic Republic of the Congo; Drug Combinations; Drug Resistance; Gene Frequency; Humans; Longitudinal Studies; Malaria, Falciparum; Membrane Transport Proteins; Middle Aged; Mutation; Plasmodium falciparum; Prevalence; Protozoan Proteins; Pyrimethamine; Spatio-Temporal Analysis; Sulfadoxine; Young Adult | 2019 |
Mathematical models for within-host competition of malaria parasites.
Topics: Algorithms; Animals; Antimalarials; Chloroquine; Computer Simulation; Drug Resistance; Host-Parasite Interactions; Humans; Immune System; Malaria; Models, Theoretical; Plasmodium falciparum; Probability; Pyrimethamine | 2019 |
Antimalarial Drug Resistance Profiling of Plasmodium falciparum Infections in Ghana Using Molecular Inversion Probes and Next-Generation Sequencing.
Topics: Adolescent; Antimalarials; Artemisinins; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Ghana; High-Throughput Nucleotide Sequencing; Humans; Infant; Malaria, Falciparum; Multidrug Resistance-Associated Proteins; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2020 |
Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites.
Topics: Antimalarials; Benzimidazoles; Binding Sites; Chloroquine; Drug Repositioning; Drug Resistance; Erythrocytes; Hemeproteins; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Lapatinib; Molecular Docking Simulation; Plasmodium falciparum; Pyrimethamine; Pyrimidines; Thermodynamics | 2020 |
Nationwide Monitoring for Plasmodium falciparum Drug-Resistance Alleles to Chloroquine, Sulfadoxine, and Pyrimethamine, Haiti, 2016-2017.
Topics: Alleles; Antimalarials; Chloroquine; Drug Resistance; Haiti; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Pyrimethamine; Sulfadoxine | 2020 |
The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC.
Topics: Antimalarials; Chloroquine; Democratic Republic of the Congo; Drug Combinations; Drug Resistance; Genome, Protozoan; Genotype; Geography; Haplotypes; Humans; Malaria, Falciparum; Mutation; Plasmodium falciparum; Polymorphism, Single Nucleotide; Principal Component Analysis; Pyrimethamine; Sulfadoxine | 2020 |
Antimalarial drug resistance molecular makers of Plasmodium falciparum isolates from Sudan during 2015-2017.
Topics: Adolescent; Antimalarials; Child; Chloroquine; Drug Resistance; Female; Humans; Malaria; Male; Membrane Transport Proteins; Mutation; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sudan; Sulfadoxine; Tetrahydrofolate Dehydrogenase; Young Adult | 2020 |
Establishing a National Molecular Surveillance Program for the Detection of
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Female; Haiti; Humans; Infant; Malaria, Falciparum; Male; Middle Aged; Plasmodium falciparum; Pyrimethamine; Sentinel Surveillance; Sulfadoxine; Young Adult | 2020 |
Assessment of antimalarial drug resistant markers in asymptomatic Plasmodium falciparum infections after 4 years of indoor residual spraying in Northern Ghana.
Topics: Amodiaquine; Antimalarials; Biomarkers, Pharmacological; Carrier State; Child, Preschool; Chloroquine; DNA, Protozoan; Drug Combinations; Drug Resistance; Female; Genotype; Ghana; Humans; Infant; Malaria; Malaria, Falciparum; Male; Plasmodium falciparum; Polymerase Chain Reaction; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2020 |
Simultaneous Determination of Chloroquine and Pyrimethamine with Cetirizine in an Active Form and Human Serum by RP-HPLC.
Topics: Cetirizine; Chloroquine; Chromatography, High Pressure Liquid; Humans; Pyrimethamine; Reproducibility of Results | 2021 |
In vivo antimalarial activity of a probiotic bacterium Lactobacillus sakei isolated from traditionally fermented milk in BALB/c mice infected with Plasmodium berghei ANKA.
Topics: Animals; Antimalarials; Cameroon; Chloroquine; Disease Models, Animal; Drug Combinations; Fermented Foods; Latilactobacillus sakei; Malaria; Mice; Mice, Inbred BALB C; Milk; Parasitemia; Plasmodium berghei; Probiotics; Pyrimethamine; Sulfadoxine | 2021 |
Chloroquine and pyrimethamine inhibit the replication of human respiratory syncytial virus A.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Chloroquine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Mice; Mice, Inbred BALB C; Pyrimethamine; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Ribavirin; Virus Replication | 2021 |
Population genomics and evidence of clonal replacement of Plasmodium falciparum in the Peruvian Amazon.
Topics: Antiprotozoal Agents; Chloroquine; Drug Resistance; Evolution, Molecular; Gene Frequency; Genome, Protozoan; Mosquito Vectors; Peru; Plasmodium falciparum; Polymorphism, Single Nucleotide; Pyrimethamine; Sulfadoxine | 2021 |
Effect of adverse events on non-adherence and study non-completion in malaria chemoprevention during pregnancy trial: A nested case control study.
Topics: Antimalarials; Case-Control Studies; Chemoprevention; Chloroquine; Data Analysis; Drug Combinations; Female; Humans; Incidence; Malaria; Medication Adherence; Models, Theoretical; Pregnancy; Pregnancy Complications, Parasitic; Pyrimethamine; Sulfadoxine | 2022 |
Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya.
Topics: Antimalarials; Child; Chloroquine; Codon; Drug Combinations; Drug Resistance; Folic Acid Antagonists; High-Throughput Nucleotide Sequencing; Humans; Kenya; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2022 |
Molecular Markers for Sulfadoxine/Pyrimethamine and Chloroquine Resistance in Plasmodium falciparum in Thailand.
Topics: Antimalarials; Chloroquine; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Pyrimethamine; Sulfadoxine; Thailand | 2022 |
Molecular surveillance for anti-malarial drug resistance and genetic diversity of Plasmodium falciparum after chloroquine and sulfadoxine-pyrimethamine withdrawal in Quibdo, Colombia, 2018.
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Chloroquine; Codon; Colombia; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Plasmodium falciparum; Polymorphism, Genetic; Pyrimethamine; Sulfadoxine | 2022 |
Topics: Antimalarials; Artemether; Artemether, Lumefantrine Drug Combination; Chloroquine; Ghana; Humans; Lumefantrine; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine | 2022 |
Molecular surveillance of anti-malarial drug resistance genes in Plasmodium falciparum isolates in Odisha, India.
Topics: Antimalarials; Artesunate; Chloroquine; Drug Combinations; Drug Resistance; Humans; India; Malaria, Falciparum; Plasmodium falciparum; Protozoan Proteins; Pyrimethamine; Sulfadoxine | 2022 |
Inhibitory effects on bovine babesial infection by iron chelator, 1-(N-acetyl-6-aminohexyl)- 3-hydroxy-2-methylpyridin-4-one (CM1), and antimalarial drugs.
Topics: Animals; Antimalarials; Babesia; Babesiosis; Cattle; Cattle Diseases; Chloroquine; Humans; Inhibitory Concentration 50; Iron Chelating Agents; Mammals; Primaquine; Pyrimethamine | 2023 |