pyrimethamine has been researched along with 2,4-diaminopyrimidine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergmann, B; Kansy, M; Seydel, JK; Walter, RD; Wiese, M | 1 |
| Griffin, RJ; Lambert, PA; Sansom, CE; Schwalbe, CH; Stevens, MF | 1 |
| Cheng, CC; Roth, B | 1 |
| Gorrod, JW; Watkins, PJ | 1 |
| Baptista, JA; Canotilho, J; Castro, RAE; Eusébio, MES; Évora, AOL; Maria, TMR; Ramos Silva, M; Rosado, MTS | 1 |
1 review(s) available for pyrimethamine and 2,4-diaminopyrimidine
| Article | Year |
|---|---|
Recent progress in the medicinal chemistry of 2,4-diaminopyrimidines.
Topics: Amino Acid Sequence; Animals; Folic Acid Antagonists; Glutamates; Glutamic Acid; Malaria; Mathematics; Methotrexate; Microbial Sensitivity Tests; Models, Chemical; Pyrimethamine; Pyrimidines; Quinazolines; Stereoisomerism; Triazines | 1982 |
4 other study(ies) available for pyrimethamine and 2,4-diaminopyrimidine
| Article | Year |
|---|---|
Pyrimethamin-resistant Plasmodium falciparum lack cross-resistance to methotrexate and 2,4-diamino-5-(substituted benzyl) pyrimidines.
Topics: Animals; Drug Resistance; Folic Acid Antagonists; Methotrexate; Plasmodium falciparum; Pyrimethamine; Pyrimidines | 1991 |
Structural studies on bio-active compounds. Part XV. Structure-activity relationships for pyrimethamine and a series of diaminopyrimidine analogues versus bacterial dihydrofolate reductase.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Computer Graphics; Escherichia coli; Folic Acid Antagonists; Liver; Models, Molecular; Pyrimethamine; Pyrimidines; Rats; Structure-Activity Relationship; Thermodynamics | 1989 |
Determination of isomeric N-oxide metabolites of some substituted 2,4-diaminopyrimidines by reversed-phase ion-pair high-performance liquid chromatography.
Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cricetinae; Dioctyl Sulfosuccinic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Isomerism; Microsomes, Liver; Oxides; Pyrimethamine; Pyrimidines; Surface-Active Agents; Trimethoprim | 1993 |
Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening.
Topics: Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Pyrimethamine; Pyrimidines; Tetrahydrofolate Dehydrogenase; Trimethoprim | 2021 |