Page last updated: 2024-08-16

pyrilamine and triprolidine

pyrilamine has been researched along with triprolidine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's2 (10.53)18.2507
2000's6 (31.58)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Bakker, RA; Booth, RG; Choksi, NY; Leurs, R; Moniri, NH; Nix, WB; Timmerman, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Braga, F; Mota, I1
Hill, SJ; Marrian, DH; Young, JM1
Garcia Agudo, NL; Gonçalves, JM; Sugavara, S1
Hatano, K; Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Matsuzawa, T; Nunoki, K; Watanabe, T; Yanai, K1
Harden, TK; Hepler, JR; Hughes, AR; Martin, MW; Nakahata, N1
Nicholson, AN; Pascoe, PA; Stone, BM1
Fleisch, JH; Haisch, KD; Rinkema, LE; Whitesitt, CA1
Codolà, R; García, A1
Holder, CL; Thompson, HC1
Akaike, N; Munakata, M1
Kolaczkowska, E; Plytycz, B; Seljelid, R1
Davio, C; Fernández, N; Fitzsimons, CP; Monczor, F; Shayo, C1
Keseru, GM; Kiss, R; Kovári, Z1
Holopainen, IE; Kukko-Lukjanov, TK; Michelsen, KA; Panula, P; Soini, S; Taira, T1
Tabarean, IV1

Other Studies

19 other study(ies) available for pyrilamine and triprolidine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1

    Topics: Animals; Binding, Competitive; Cell Membrane; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; DNA, Complementary; Guinea Pigs; Histamine; Histamine Agonists; Humans; Ileum; Inositol Phosphates; Ligands; NF-kappa B; Pyrilamine; Radiopharmaceuticals; Receptors, Histamine H1; Tetrahydronaphthalenes; Thermodynamics; Transfection; Type C Phospholipases

2002
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Homologous passive cutaneous anaphylaxis (PCA) in mice and heterologous PCA induced in rats with mouse IgE.
    Immunology, 1976, Volume: 30, Issue:5

    Topics: Animals; Cromolyn Sodium; Cyclic AMP; Depression, Chemical; Diethylcarbamazine; Epinephrine; Female; Immunoglobulin E; Immunoglobulin G; Isoproterenol; Male; Methysergide; Mice; Mice, Inbred A; Passive Cutaneous Anaphylaxis; Phenoxybenzamine; Pyrilamine; Rats; Serotonin Antagonists; Theophylline; Triprolidine

1976
Specific binding of 3H-mepyramine to histamine H1 receptors in intestinal smooth muscle.
    Nature, 1977, Nov-24, Volume: 270, Issue:5635

    Topics: Animals; Binding, Competitive; Chlorpheniramine; Guinea Pigs; In Vitro Techniques; Intestine, Small; Kinetics; Muscle, Smooth; Promethazine; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Triprolidine

1977
Local increase of vascular permeability induced by pyridoxal-5'-phosphate in the rat skin.
    Anais da Academia Brasileira de Ciencias, 1975, Volume: 47, Issue:3-4

    Topics: Animals; Capillary Permeability; Male; Mast Cells; Pyridoxal Phosphate; Pyrilamine; Rats; Skin; Stimulation, Chemical; Triprolidine

1975
Visualization of histamine H1 receptors in dog brain by positron emission tomography.
    Neuroscience letters, 1990, Oct-02, Volume: 118, Issue:1

    Topics: Animals; Brain; Dogs; Doxepin; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed; Triprolidine

1990
H1-histamine receptors on human astrocytoma cells.
    Molecular pharmacology, 1986, Volume: 29, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; GTP-Binding Proteins; Histamine; Humans; Pertussis Toxin; Phosphatidylinositols; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Triprolidine; Tritium; Virulence Factors, Bordetella

1986
Histaminergic systems and sleep. Studies in man with H1 and H2 antagonists.
    Neuropharmacology, 1985, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Brompheniramine; Cimetidine; Electroencephalography; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Phenothiazines; Psychomotor Performance; Pyrilamine; Ranitidine; Sleep; Sleep Stages; Sleep, REM; Triprolidine

1985
Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist.
    Agents and actions, 1987, Volume: 20, Issue:1-2

    Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Chlorpheniramine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Muscle, Smooth; Promethazine; Pyrilamine; Terfenadine; Triprolidine

1987
Effect of thyroid state on histamine H1 receptors in adult and developing rat brain.
    Biochemical pharmacology, 1985, Dec-01, Volume: 34, Issue:23

    Topics: Age Factors; Animals; Brain Chemistry; Female; Hyperthyroidism; Hypothyroidism; Male; Propylthiouracil; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Thyroxine; Triprolidine

1985
Trace analysis of the antihistamines methapyrilene hydrochloride, pyrilamine maleate and triprolidine hydrochloride monohydrate in animal feed, human urine and wastewater by high-performance liquid chromatography and gas chromatography with nitrogen-phosp
    Journal of chromatography, 1984, Jan-20, Volume: 283

    Topics: Animal Feed; Chromatography, Gas; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Methapyrilene; Pyrilamine; Sewage; Triprolidine; Waste Disposal, Fluid

1984
Regulation of K+ conductance by histamine H1 and H2 receptors in neurones dissociated from rat neostriatum.
    The Journal of physiology, 1994, Oct-15, Volume: 480 ( Pt 2)

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Histamine; Histamine Agonists; Impromidine; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Methylhistamines; Neostriatum; Potassium; Potassium Channels; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Triprolidine

1994
Role of mast cells in zymosan-induced peritoneal inflammation in Balb/c and mast cell-deficient WBB6F1 mice.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Cimetidine; Cromolyn Sodium; Histamine Antagonists; Hypoglycemic Agents; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Knockout; Peritonitis; Pyrilamine; Ranitidine; Receptors, Histamine; Triprolidine; Zymosan

2001
Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.
    The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33

    Topics: Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Histamine H1 Antagonists; Inositol Phosphates; Ligands; Models, Chemical; Protein Binding; Pyrilamine; Receptors, Histamine H1; Triprolidine

2004
Homology modelling and binding site mapping of the human histamine H1 receptor.
    European journal of medicinal chemistry, 2004, Volume: 39, Issue:11

    Topics: Algorithms; Amino Acid Sequence; Animals; Binding Sites; Cattle; Computer Simulation; Drug Interactions; Histamine Agonists; Histamine Antagonists; Humans; Loratadine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyrilamine; Receptors, Histamine H1; Rhodopsin; Sequence Homology, Amino Acid; Triprolidine

2004
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4

    Topics: Animals; Cell Death; Cells, Cultured; Coculture Techniques; Convulsants; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus, Anterior; Hypothalamus, Posterior; Imidazoles; Kainic Acid; Methylhistidines; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3; Thiourea; Triprolidine

2006
Persistent histamine excitation of glutamatergic preoptic neurons.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Action Potentials; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glutamine; Histamine; Mice; Mice, Inbred C57BL; Neurons; Preoptic Area; Pyrilamine; Receptors, Histamine H1; RNA, Messenger; Signal Transduction; Triprolidine; TRPC Cation Channels; Type C Phospholipases; Vesicular Glutamate Transport Protein 2

2012