pyrilamine has been researched along with piperidines in 93 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (9.68) | 18.7374 |
| 1990's | 45 (48.39) | 18.2507 |
| 2000's | 29 (31.18) | 29.6817 |
| 2010's | 10 (10.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clapham, J; Kilpatrick, GJ | 2 |
| Maeyama, K; Onodera, K; Sakai, N; Watanabe, T; Yanai, K | 1 |
| Ballabeni, V; Barocelli, E; Impicciatore, M; Lavezzo, A; Morini, G | 1 |
| Fukui, H; Inagaki, N; Kanamura, A; Kondou, H; Koyama, Y; Wada, H | 1 |
| Barnes, PJ; Ichinose, M | 1 |
| Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE | 1 |
| Garbarg, M; Gros, C; Schwartz, JC; Tuong, MD | 1 |
| Ahn, HS; Barnett, A | 1 |
| Kawasaki, H; Takasaki, K | 1 |
| Bevan, J; Heptinstall, S | 2 |
| Laduron, PM; Leysen, JE; Van Dun, J; Wouters, W | 1 |
| Baggiolini, M; Martin, U | 1 |
| Langwiński, R; Malec, D | 1 |
| Ahn, HS; Barnett, A; Gulbenkian, A; Iorio, LC; Kreutner, W; Tozzi, S | 1 |
| Imano, K; Ishii, K; Karasawa, T; Nakamura, H; Seto, Y; Takeyama, K; Yakuo, I | 1 |
| Fleckenstein, AE; Lookingland, KJ; Moore, KE | 2 |
| Kohno, S; Nabe, T; Nakao, S; Ogawa, K; Ohata, K; Yamamura, H | 1 |
| Drazen, JM; Haley, KJ; Hall, AE; Kobzik, L; Lilly, CM; Rodger, IW | 1 |
| Ballabeni, V; Barocelli, E; Chiavarini, M; Impicciatore, M | 1 |
| Kohno, S; Nabe, T; Ogawa, K; Ohata, K; Yamamura, H | 1 |
| Carson, CC; Davies, MG; Hagen, PO; Kim, YC; Lee, TH | 1 |
| Abe, T; Ikeda, Y; Matsuda, K; Matsumura, T; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Schilling, L; Wahl, M | 1 |
| Enomoto, K; Maeno, T | 1 |
| Kamondi, A; Reiner, PB | 1 |
| Brideau, C; Chan, CC; Ho, E; Rodger, IW; Savoie, C; Tousignant, C | 1 |
| Adachi, N; Hirakawa, M; Itano, Y; Oishi, R; Saeki, K; Yamada, T | 1 |
| Bristow, DR; Zamani, MR | 1 |
| Kamei, C; Tasaka, K | 1 |
| Everaert, E; Germonpré, PR; Joos, GF; Kips, JC; Pauwels, RA | 1 |
| Konno, K; Nakata, J; Takeyama, K; Tamaoki, J | 1 |
| Antunes, E; Brain, SD; Costa, SK; de Nucci, G; Palframan, RT; Wilsoncroft, P | 1 |
| KAMEI, CH | 1 |
| Akiyama, K; Maeda, Y; Mita, H; Saito, H; Shimizu, H | 1 |
| Davison, JS; Jennings, LJ; Pariente, JA; Salido, GM; Sharkey, KA; Singh, J | 1 |
| Eaton, SJ; Eoh, S; Harrington, ME; Hoque, S; Meyer, J | 1 |
| Gudermann, T; Harteneck, C; Kühn, B; Schmid, A; Schultz, G | 1 |
| Chiyotani, A; Konno, K; Nakata, J; Takeyama, K; Tamaoki, J | 1 |
| Ito, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Hayashi, Y; Kagawa, K; Mammoto, T; Mashimo, T; Yamamoto, Y; Yamatodani, A; Yoshiya, I | 1 |
| Imaizumi, M; Miyazaki, S; Onodera, K; Timmerman, H | 1 |
| Bivalacqua, TJ; Champion, HC; Czapla, MA; Ilgenfritz, C; Kadowitz, PJ; Santiago, JA | 1 |
| Lecklin, A; Tuomisto, L | 1 |
| Cusack, B; Groshan, K; Richelson, E; Tyler, BM | 1 |
| Itoh, C; Onodera, K; Sato, M; Watanabe, T | 1 |
| Acuña, Y; Campos, HA; Israel, A; Mathison, Y | 1 |
| Jokinen, M; Laitinen, JT | 1 |
| Grundy, D; Haupt, W; Kirkup, AJ; Kreis, ME | 1 |
| Hijikuro, K; Iizuka, T; Inaba, K; Kamitani, T; Shizawa, T; Yanoshita, R; Yoshida, F | 1 |
| Costentin, J; Dubuc, I; Remande, S | 1 |
| Chen, Z; Fujii, Y; Kamei, C; Sugimoto, Y; Suzuki, G | 1 |
| Calixto, JB; Campos, MM; Ferreira, PK | 1 |
| Kamiki, T; Kohno, S; Nabe, T; Tanpo, T; Yasui, K | 1 |
| Antunes, E; Costa, SK; da Silva, GR; Linardi, A | 1 |
| Anichtchik, OV; Panula, P; Peitsaro, N | 1 |
| Hishinuma, S; Ogura, K | 1 |
| Ikarashi, Y; Ishige, A; Kuribara, H; Maruyama, Y; Sasaki, H; Yuzurihara, M | 1 |
| Asselin, ML; Coquerel, A; Costentin, J; Dubuc, I | 1 |
| Gitlin, JM; Mitchell, JA; Stanford, SJ | 1 |
| Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I | 1 |
| Ghosh, AK; Hirasawa, N; Ohuchi, K | 1 |
| Eltorp, CT; Hansen, AJ; Ingvardsen, BK; Jørgensen, TK; Lundbaek, JA; Olsen, UB; Thomsen, C | 1 |
| Ito, T; Yabuuchi, M; Yakuo, I | 1 |
| Chen, Z; Li, WD; Shen, YJ; Wei, EQ; Zhu, LJ | 1 |
| Bischoff, AM; Büsselberg, D; Dutschmann, M; Richter, DW | 1 |
| Chen, Z; Hu, WW; Huang, YW; Wei, EQ; Yanai, K; Zhang, LS | 1 |
| Bacon, KB; Gantner, F; Sakai, K; Takeshita, K | 1 |
| Dickenson, AH; Edwards, M; Suzuki, R | 1 |
| Brzozowski, T; Ceranowicz, P; Dembiński, A; Dembiński, M; Konturek, SJ; Pawlik, WW; Warzecha, Z | 1 |
| Eckman, JR; Wagner, MC; Wick, TM | 1 |
| Holopainen, IE; Kukko-Lukjanov, TK; Michelsen, KA; Panula, P; Soini, S; Taira, T | 1 |
| Gálfi, M; Juhász, A; László, F; László, FA; Molnár, A; Radács, M; Varga, C | 1 |
| Adachi, Y; Fujii, Y; Kamei, C; Yamamoto, Y | 1 |
| Adachi, N; Arai, T; Hiraga, N; Liu, K; Nagaro, T | 1 |
| Dutschmann, M; Gratzl, M; Lazarov, N; Reindl, S; Rey-Ares, V; Rozloznik, M | 1 |
| Krishna, DR; Kumar, KV; Palit, G | 1 |
| Kamei, C; Masuoka, T; Saito, S | 1 |
| Chen, Z; Hu, DN; Liu, CQ; Liu, FX; Luo, JH | 1 |
| Alcayaga, J; Del Rio, R; Fujiwara, K; Iturriaga, R; Koenig, CS; Moya, EA | 1 |
| Hirasawa, N; Hong, J; Ishihara, K; Katoh, G; Ohsawa, Y; Ohuchi, K; Seyama, T; Shibata, K; Tamura, S | 1 |
| Bina, P; Nasehi, M; Piri, M; Zarrindast, MR | 1 |
| Cauley, M; Cousins, V; Hampton, D; Levin, ED; Petro, A; Pruitt, M; Rose, J; Slade, S; Wells, C | 1 |
| Ji, W; Kawamata, T; Liang, J | 1 |
| Hirasawa, N; Ohuchi, K | 1 |
| Browning, C; Clark, KL; Connor, HE; Ford, AJ; Hall, DA; Hodgson, ST; Luttmann, MA; Russell, LJ; Saunders, KA; Slack, RJ | 1 |
| Fukui, H; Hattori, M; Mizuguchi, H; Ono, S | 1 |
| Alisch, R; Buschauer, A; Elz, S; Sadek, B | 1 |
| Bahi, A; Kieć-Kononowicz, K; Nurulain, SM; Sadek, B; Łażewska, D | 1 |
| Darras, FH; Decker, M; Khan, N; Nurulain, SM; Saad, A; Sadek, B | 1 |
| Alachkar, A; Gryboś, A; Handzlik, J; Honkisz, E; Kiec-Kononowicz, K; Latacz, G; Lubelska, A; Sadek, B; Siwek, A; Stark, H; Łażewska, D | 1 |
1 review(s) available for pyrilamine and piperidines
| Article | Year |
|---|---|
[Roles of histamine in the exacerbated allergic dermatitis].
Topics: Animals; Cyclosporine; Dermatitis, Atopic; Disease Models, Animal; Drug Therapy, Combination; Histamine; Histamine Antagonists; Humans; Mice; Picryl Chloride; Piperidines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3; Receptors, Histamine H4; Tetradecanoylphorbol Acetate | 2011 |
92 other study(ies) available for pyrilamine and piperidines
| Article | Year |
|---|---|
Histamine H3 receptors modulate the release of [3H]-acetylcholine from slices of rat entorhinal cortex: evidence for the possible existence of H3 receptor subtypes.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Hippocampus; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Piperidines; Potassium; Pyrilamine; Ranitidine; Rats; Receptors, Histamine; Receptors, Histamine H3 | 1992 |
Effects of thioperamide, a histamine H3 receptor antagonist, on locomotor activity and brain histamine content in mast cell-deficient W/Wv mice.
Topics: Animals; Benzothiazoles; Brain Chemistry; Dopamine; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Mast Cells; Methylhistamines; Mice; Mice, Mutant Strains; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine H3; Thiazoles | 1991 |
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Male; Muscle Contraction; Piperidines; Pirenzepine; Potassium; Pyrilamine; Receptors, Muscarinic | 1990 |
Histamine-induced inositol phosphate accumulation in type-2 astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Chlorpheniramine; Famotidine; Histamine; Inositol Phosphates; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine | 1991 |
Histamine H3 receptors modulate antigen-induced bronchoconstriction in guinea pigs.
Topics: Animals; Antigens; Bronchoconstriction; Cimetidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Guinea Pigs; Histamine; Immunization; Male; Ovalbumin; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Skin Tests | 1990 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats | 1990 |
Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain.
Topics: Animals; Brain; Brain Chemistry; Cyclic AMP; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; In Vitro Techniques; Male; Methylhistamines; Neurons; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H3 | 1989 |
Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine.
Topics: Aminopyridines; Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Loratadine; Lung; Male; Piperidines; Pyrilamine; Receptors, Cell Surface | 1986 |
Central alpha-2 adrenoceptor-mediated hypertensive response to clonidine in conscious, normotensive rats.
Topics: Animals; Azepines; Blood Pressure; Brain; Cimetidine; Clonidine; Hydroxydopamines; Injections, Intraventricular; Ketanserin; Male; Methoxamine; Oxidopamine; Piperidines; Prazosin; Procaine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Yohimbine | 1986 |
Serotonin-induced platelet aggregation in whole blood and the effects of ketanserin and mepyramine.
Topics: Aminopyridines; Dose-Response Relationship, Drug; Humans; Ketanserin; Piperidines; Platelet Aggregation; Pyrilamine; Serotonin; Time Factors | 1985 |
Differential photoaffinity labelling of serotonin-S2 receptors and histamine-H1 receptors using 7-azidoketanserin.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Butyrophenones; Cerebellum; Cerebral Cortex; Female; Guinea Pigs; Ketanserin; Photolysis; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Serotonin; Spiperone | 1985 |
Dissociation between the anti-anaphylactic and the anti-histaminic actions of ketotifen.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Clemastine; Female; Histamine H1 Antagonists; Ketotifen; Piperidines; Pyrilamine; Rats; Skin Tests; Thiophenes | 1981 |
The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol.
Topics: Analgesics; Analgesics, Opioid; Animals; Catalepsy; Cimetidine; Diphenhydramine; Drug Interactions; Female; Haloperidol; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains | 1983 |
Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine.
Topics: Animals; Anticonvulsants; Autonomic Nervous System; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Dioxanes; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hypnotics and Sedatives; Lethal Dose 50; Loratadine; Male; Mice; Physostigmine; Piperidines; Pyrilamine; Rats; Saimiri; Time Factors | 1984 |
Effects of ketanserin and mepyramine on platelet aggregation and on the uptake of 5-hydroxytryptamine into platelets.
Topics: Adenosine Diphosphate; Aminopyridines; Blood Platelets; Humans; Ketanserin; Piperidines; Platelet Aggregation; Pyrilamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1983 |
[Pharmacological study of ebastine, a novel histamine H1-receptor antagonist].
Topics: Administration, Oral; Animals; Butyrophenones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity; In Vitro Techniques; Male; Phenothiazines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Terfenadine | 1994 |
Histaminergic neurons mediate restraint stress-induced activation of central 5-hydroxytryptaminergic neurons in the rat.
Topics: Animals; Benzothiazoles; Histamine; Histamine H2 Antagonists; Histidine Decarboxylase; Hydroxyindoleacetic Acid; Male; Methylhistidines; Neurons; Nucleus Accumbens; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Receptors, Histamine H1; Restraint, Physical; Serotonin; Suprachiasmatic Nucleus; Thiazoles | 1994 |
Possible participation of histamine H3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells.
Topics: Anaphylaxis; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mast Cells; Methylhistamines; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Peritoneum; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3 | 1994 |
Substance P-induced histamine release in tracheally perfused guinea pig lungs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Mast Cells; Perfusion; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1995 |
R-alpha-methylhistamine-induced inhibition of gastric acid secretion in pylorus-ligated rats via central histamine H3 receptors.
Topics: Animals; Cimetidine; Female; Gastric Acid; Gastric Mucosa; Histamine Agonists; Histamine Antagonists; Injections, Intraventricular; Methylhistamines; Piperidines; Pylorus; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3 | 1995 |
Dimaprit, a histamine H2-agonist, inhibits anaphylactic histamine release from mast cells and the decreased release is restored by thioperamide (H3-antagonist), but not by cimetidine (H2-antagonist).
Topics: Anaphylaxis; Animals; Anticonvulsants; Betahistine; Cimetidine; Dimaprit; Histamine H2 Antagonists; Histamine Release; In Vitro Techniques; Indicators and Reagents; Male; Mast Cells; Piperidines; Pyrilamine; Rats; Rats, Wistar | 1993 |
Characterization and function of histamine receptors in corpus cavernosum.
Topics: Acetylcholine; Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Papaverine; Penis; Piperidines; Pyrilamine; Rabbits; Receptors, Histamine; Thiazoles | 1995 |
Antiallergic effect of ZCR-2060: antihistaminic action.
Topics: Animals; Benzoates; Brain; Dermatitis, Contact; Exploratory Behavior; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hypersensitivity; In Vitro Techniques; Lung; Male; Membranes; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Sleep; Thiopental | 1994 |
Activation of noradrenergic neurons projecting to the diencephalon following central administration of histamine is mediated by H1 receptors.
Topics: Animals; Benzothiazoles; Cerebral Ventricles; Diencephalon; Histamine; Histamine H2 Antagonists; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenoxypropanolamines; Piperidines; Preoptic Area; Pyrilamine; Rats; Receptors, Histamine H1; Thiazoles | 1994 |
Effects of antihistaminics on experimental brain edema.
Topics: Animals; Antioxidants; Benzothiazoles; Blood-Brain Barrier; Brain Edema; Dexamethasone; Freezing; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Lipid Peroxidation; Male; Parietal Lobe; Phenoxypropanolamines; Piperidines; Pregnatrienes; Pyrilamine; Rats; Rats, Sprague-Dawley; Thiazoles; Water-Electrolyte Balance | 1994 |
Effects of vesicular acetylcholine uptake blockers on frequency augmentation-potentiation in frog neuromuscular transmission.
Topics: Acetylcholine; Animals; Antidepressive Agents; Azepines; Chloroquine; Ethacridine; Evoked Potentials; In Vitro Techniques; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Piperidines; Pyrilamine; Quinacrine; Ranidae; Regression Analysis; Synaptic Transmission | 1994 |
Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current.
Topics: Cerebral Cortex; Cimetidine; Evoked Potentials; Histamine; Histamine Antagonists; Humans; Hypnotics and Sedatives; Membrane Potentials; Neurons; Piperidines; Potassium Channels; Pyrilamine; Receptors, Histamine H1 | 1994 |
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique.
Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Neurokinin A; Parasympatholytics; Piperidines; Plethysmography; Propionates; Pyrilamine; Quinolines | 1994 |
Aggravation of ischemic neuronal damage in the rat hippocampus by impairment of histaminergic neurotransmission.
Topics: Animals; Benzothiazoles; Brain Ischemia; Cell Death; Hippocampus; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; Methylhistidines; Neurons; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Synaptic Transmission; Thiazoles | 1993 |
Desensitization of histamine H1 receptor-mediated inositol phosphate production in HeLa cells.
Topics: Bradykinin; HeLa Cells; Histamine; Humans; Inositol; Inositol Phosphates; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sodium Fluoride | 1993 |
Effect of histamine on memory retrieval in old rats.
Topics: Acetylcholine; Aging; Animals; Anticonvulsants; Avoidance Learning; Cerebrovascular Circulation; Cimetidine; Dose-Response Relationship, Drug; Exploratory Behavior; Histamine; Histamine Agonists; Injections, Intraventricular; Male; Memory; Methylhistamines; Motor Activity; Piperidines; Pyrilamine; Rats; Rats, Wistar | 1993 |
Histamine H3 receptor-mediated modulation of water consumption in the rat.
Topics: Animals; Drinking; Histamine; Histamine Antagonists; Male; Methylhistamines; Nicotinic Acids; Piperidines; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H3; Tetrazoles; Triazoles | 1993 |
Characterization of neurogenic inflammation in the airways of two highly inbred rat strains.
Topics: Animals; Benzamides; Blood Pressure; Bronchi; Capillary Permeability; Capsaicin; Cimetidine; Coloring Agents; Dose-Response Relationship, Drug; Evans Blue; Histamine Antagonists; Indoles; Inflammation; Isoindoles; Methysergide; Neurokinin-1 Receptor Antagonists; Piperidines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Neurokinin-1; Serotonin; Serotonin Antagonists; Substance P; Trachea | 1995 |
Effect of oxitropium bromide on histamine-induced airway goblet cell secretion.
Topics: Administration, Inhalation; Aerosols; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Histocytochemistry; Injections, Intravenous; Male; Mucus; Muscarinic Antagonists; Piperidines; Pyrilamine; Receptors, Histamine; Scopolamine Derivatives; Trachea; Vagus Nerve | 1996 |
The effect of a tachykinin NK1 receptor antagonist, SR140333, on oedema formation induced in rat skin by venom from the Phoneutria nigriventer spider.
Topics: Animals; Edema; Male; Methysergide; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Pyrilamine; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-1; Skin Diseases; Spider Venoms; Substance P | 1996 |
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR.
Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Iris; Lethal Dose 50; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Piperidines; Potassium; Pyrilamine; Ranitidine; Receptors, Histamine H1; Substance P | 1996 |
Histamine augments VCAM-1 expression on IL-4- and TNF-alpha-stimulated human umbilical vein endothelial cells.
Topics: Amanitins; Antibodies, Blocking; Antigens, CD; Cell Adhesion; Cells, Cultured; Cimetidine; Eosinophils; Histamine; Histamine Antagonists; Humans; Immunohistochemistry; Integrin alpha4; Interleukin-4; Piperidines; Platelet Activating Factor; Pyrilamine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1996 |
Control of exocrine secretion in the guinea-pig pancreas by histamine H3 receptors.
Topics: alpha-Amylases; Animals; Choline; Electric Stimulation; Female; Guinea Pigs; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Pancreas; Piperidines; Pyrilamine; Receptors, Histamine H3; Tritium | 1996 |
Circadian rhythm photic phase shifts are not altered by histamine receptor antagonists.
Topics: Animals; Benzothiazoles; Cimetidine; Circadian Rhythm; Cricetinae; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mesocricetus; Phenoxypropanolamines; Photoperiod; Piperidines; Pyrilamine; Receptors, Histamine H3; Thiazoles | 1996 |
G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Baculoviridae; Binding, Competitive; Cell Membrane; COS Cells; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; Inositol Phosphates; Insecta; Male; Pertussis Toxin; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Recombinant Proteins; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Histamine H2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes.
Topics: Amine Oxidase (Copper-Containing); Animals; Asthma; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine N-Methyltransferase; Male; Methylhistamines; Mucus; Piperidines; Pyrilamine; Recombinant Proteins; Trachea | 1997 |
Effects of histamine agents on methamphetamine-induced stereotyped behavior and behavioral sensitization in rats.
Topics: Animals; Benzothiazoles; Brain; Central Nervous System Stimulants; Histamine Agents; Histidine; Male; Methamphetamine; Methylhistidines; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Stereotyped Behavior; Thiazoles | 1997 |
Interactions between neuronal histamine and halothane anesthesia in rats.
Topics: Anesthetics, Inhalation; Animals; Benzothiazoles; Drug Interactions; Enzyme Inhibitors; Halothane; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Male; Methylhistidines; Microdialysis; Neurons; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
Effects of clobenpropit (VUF-9153), a histamine H3-receptor antagonist, on learning and memory, and on cholinergic and monoaminergic systems in mice.
Topics: Acetylcholine; Animals; Avoidance Learning; Benzothiazoles; Biogenic Monoamines; Brain; Drug Interactions; Histamine Antagonists; Histamine H2 Antagonists; Imidazoles; Male; Memory; Methylhistamines; Mice; Mice, Inbred ICR; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Scopolamine; Thiazoles; Thiourea | 1997 |
Comparison of responses to T-kinin and bradykinin in the mesenteric vascular bed of the cat.
Topics: Adamantane; Analysis of Variance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Cats; Cimetidine; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Histamine Antagonists; Male; Meclofenamic Acid; Mesentery; Morpholines; NG-Nitroarginine Methyl Ester; Piperidines; Potassium Channels; Pyrilamine | 1997 |
The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism.
Topics: Animals; Brain Chemistry; Diuresis; Enzyme Inhibitors; Feeding Behavior; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Piperidines; Pyrilamine; Pyrimethamine; Ranitidine; Rats; Rats, Wistar; Water-Electrolyte Balance | 1998 |
In vivo studies with low doses of levocabastine and diphenhydramine, but not pyrilamine, antagonize neurotensin-mediated antinociception.
Topics: Animals; Body Temperature Regulation; Diphenhydramine; Drug Evaluation, Preclinical; Histamine H1 Antagonists; Male; Mice; Neurotensin; Pain; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley | 1998 |
Motor behavioural function for histamine-dopamine interaction in brain.
Topics: Animals; Benzazepines; Benzothiazoles; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine Agents; Dopamine Antagonists; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Methamphetamine; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Stereotyped Behavior; Thiazoles | 1998 |
Thioperamide, a histamine H3-receptor blocker, facilitates vasopressor response to footshocks.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cimetidine; Electric Stimulation; Enzyme Inhibitors; Heart Rate; Hindlimb; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistidines; Norepinephrine; Phentolamine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Vasoconstrictor Agents | 1998 |
Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.
Topics: Adenosine; Animals; Autoradiography; Basal Ganglia; Brain Chemistry; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Male; Piperidines; Protein Binding; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3; Signal Transduction; Substantia Nigra; Sulfur Radioisotopes; Xanthines | 1998 |
Histamine sensitivity of mesenteric afferent nerves in the rat jejunum.
Topics: Afferent Pathways; Animals; Blood Pressure; Dimaprit; Histamine; Histamine Agonists; Histamine Antagonists; Jejunum; Muscle, Smooth; Nifedipine; Piperidines; Pyrilamine; Ranitidine; Rats; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Splanchnic Circulation | 1998 |
Mechanisms of non-drowsiness after oral administration of TMK688, a novel antiallergic drug.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Capillary Permeability; Hexobarbital; Histamine; Histamine H1 Antagonists; Male; Mice; Mice, Inbred ICR; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Sleep; Sleep Stages | 1998 |
The partial agonist properties of levocabastine in neurotensin-induced analgesia.
Topics: Analgesia; Analgesics; Animals; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Male; Mice; Neurotensin; Pain; Pain Threshold; Piperidines; Pyrilamine; Receptors, Neurotensin | 1999 |
Effects of histamine and related compounds on regional cerebral blood flow in rats.
Topics: Animals; Benzothiazoles; Blood Pressure; Brain Chemistry; Dimaprit; Diphenhydramine; Drug Interactions; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Regional Blood Flow; Thiazoles; Time Factors | 1999 |
The role of sensorial neuropeptides in the edematogenic responses mediated by B(1) agonist des-Arg(9)-BK in rats pre-treated with LPS.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Edema; Histamine H1 Antagonists; Lipopolysaccharides; Male; Methysergide; Mianserin; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; p-Methoxy-N-methylphenethylamine; Peptide Fragments; Piperidines; Pyrazoles; Pyridines; Pyrilamine; Rats; Rats, Wistar; Receptor, Bradykinin B1; Receptors, Bradykinin; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Serotonin Antagonists | 2000 |
Participation of neuropeptides in antigen-induced contraction of guinea pig bronchi via NK(2) but not NK(1) receptor stimulation.
Topics: Animals; Benzamides; Benzeneacetamides; Biphenyl Compounds; Bronchi; Bronchoconstriction; Female; gamma-Globulins; Guinea Pigs; Histamine H1 Antagonists; Leukotriene Antagonists; Male; Neurokinin-1 Receptor Antagonists; Neuropeptides; Penicillin G; Piperidines; Pyrilamine; Receptors, Neurokinin-2; Substance P; Thiazoles; Trachea | 2000 |
Involvement of kinins, mast cells and sensory neurons in the plasma exudation and paw oedema induced by staphylococcal enterotoxin B in the mouse.
Topics: Animals; Benzamides; Bradykinin; Capillary Permeability; Capsaicin; Diabetes Mellitus, Experimental; Edema; Enterotoxins; Hindlimb; Kinins; Male; Mast Cells; Mice; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Piperidines; Pyrilamine; Quinuclidines; Receptors, Neurokinin-2 | 2000 |
Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain.
Topics: Animals; Autoradiography; Brain; Cimetidine; Female; Guanosine 5'-O-(3-Thiotriphosphate); Histamine Agonists; Histamine Antagonists; Imidazoles; Kinetics; Male; Methylhistamines; Piperidines; Pyrilamine; Radioligand Assay; Receptors, Histamine H3; Sulfur Radioisotopes; Thiourea; Tritium; Zebrafish | 2000 |
Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclosporine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Okadaic Acid; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sulfonamides; Tacrolimus; Tumor Cells, Cultured | 2000 |
Effects of drugs acting as histamine releasers or histamine receptor blockers on an experimental anxiety model in mice.
Topics: Animals; Anxiety; Cimetidine; Disease Models, Animal; Histamine Antagonists; Histamine Release; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; p-Methoxy-N-methylphenethylamine; Piperidines; Pyrilamine | 2000 |
Localization of neurotensin NTS2 receptors in rat brain, using.
Topics: Animals; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Histamine H1 Antagonists; Male; Neurotensin; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
The H3 receptor is involved in cholecystokinin inhibition of food intake in rats.
Topics: Animals; Brain; Cholecystokinin; Dose-Response Relationship, Drug; Eating; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Injections, Intraperitoneal; Male; Methylhistamines; Piperidines; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H3; Sincalide; Stomach | 2001 |
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Granulation Tissue; Histamine; Histamine Antagonists; Immunohistochemistry; Indoles; Indomethacin; Inflammation; Isoquinolines; Lymphokines; Macrophages, Peritoneal; Male; Maleimides; Naphthalenes; Neovascularization, Pathologic; Piperidines; Protein Kinase C; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H2; RNA, Messenger; Specific Pathogen-Free Organisms; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation.
Topics: Animals; Benzoquinones; Binding Sites; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; Capsaicin; Carrageenan; Central Nervous System; CHO Cells; Cricetinae; Disease Models, Animal; Edema; Extravasation of Diagnostic and Therapeutic Materials; Gene Expression; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Mice; Neurogenic Inflammation; Pain; Pain Measurement; Piperidines; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Species Specificity; Spinal Cord; Transfection; Tritium | 2002 |
Preclinical comparison of ebastine and other second generation H1-antihistamines.
Topics: Animals; Butyrophenones; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Guinea Pigs; Histamine H1 Antagonists; Intracellular Membranes; Male; Passive Cutaneous Anaphylaxis; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Skin | 2001 |
Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats.
Topics: Animals; Drug Synergism; Epilepsy; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histidine; Kindling, Neurologic; Male; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3 | 2002 |
Histaminergic modulation of the intact respiratory network of adult mice.
Topics: Animals; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypoxia; Medulla Oblongata; Mice; Mice, Inbred C57BL; Nerve Net; Neurons; Phrenic Nerve; Piperidines; Pons; Pyrilamine; Receptors, Histamine H3; Respiratory System | 2003 |
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Release; Histidine; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Seizures; Thiourea | 2003 |
Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo.
Topics: Animals; Bone Marrow Cells; Carrageenan; Cimetidine; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Leukotriene B4; Mast Cells; Mice; Mice, Inbred BALB C; Neutrophil Infiltration; Piperidines; Pleurisy; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Zymosan | 2003 |
ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel histamine H1 receptor antagonist, produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and
Topics: Analgesics; Animals; Disease Models, Animal; Electrophysiology; Histamine H1 Antagonists; Inflammation; Male; Neurons; Pain; Peripheral Nervous System Diseases; Piperidines; Posterior Horn Cells; Pyrilamine; Rats; Rats, Sprague-Dawley; Spinal Cord | 2004 |
Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.
Topics: Animals; Capsaicin; DNA; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Immersion; Interleukin-1; Male; Neurons, Afferent; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Regional Blood Flow; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 2005 |
Histamine increases sickle erythrocyte adherence to endothelium.
Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules | 2006 |
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
Topics: Animals; Cell Death; Cells, Cultured; Coculture Techniques; Convulsants; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus, Anterior; Hypothalamus, Posterior; Imidazoles; Kainic Acid; Methylhistidines; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3; Thiourea; Triprolidine | 2006 |
Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Kinetics; Male; Oxytocin; Piperidines; Pituitary Gland, Posterior; Pyrilamine; Rats; Tissue Culture Techniques; Vasopressins | 2006 |
Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Diphenhydramine; Donepezil; Ginkgo biloba; Histamine; Histamine H1 Antagonists; Indans; Male; Maze Learning; Memory; Memory Disorders; Muscarinic Antagonists; Neural Pathways; Nootropic Agents; Piperidines; Plant Extracts; Pyrilamine; Rats; Rats, Wistar; Scopolamine; Synaptic Transmission; Treatment Outcome | 2007 |
Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains.
Topics: Animals; Antigens, CD; Brain Ischemia; CD4-Positive T-Lymphocytes; Cell Count; Drug Combinations; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Neutrophils; Peroxidase; Piperidines; Pyrilamine; Random Allocation; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine; Reperfusion; Time Factors | 2007 |
Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway.
Topics: Afferent Pathways; Amidines; Animals; Blotting, Northern; Carotid Body; Chemoreceptor Cells; Female; Gene Expression; Histamine; Histamine Antagonists; Histidine Decarboxylase; Immunohistochemistry; Male; Medulla Oblongata; Microscopy, Immunoelectron; Phrenic Nerve; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Respiration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Cyanide | 2006 |
Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzothiazoles; Diazepam; Dose-Response Relationship, Drug; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Mice; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3 | 2007 |
Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats.
Topics: Animals; Concanavalin A; Cycloserine; Dioxoles; Dose-Response Relationship, Drug; Electroencephalography; Fourier Analysis; GluK2 Kainate Receptor; Hippocampus; Histamine H1 Antagonists; Injections; Male; Maze Learning; Mental Recall; Orientation; Piperidines; Pyrilamine; Pyrrolidinones; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Histamine H1; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Signal Processing, Computer-Assisted; Spermidine; Spermine; Theta Rhythm | 2008 |
Apomorphine-induced turning behavior in 6-hydroxydopamine lesioned rats is increased by histidine and decreased by histidine decarboxylase, histamine H1 and H2 receptor antagonists, and an H3 receptor agonist.
Topics: Animals; Apomorphine; Basal Ganglia; Enzyme Inhibitors; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Histidine Decarboxylase; Imidazoles; Injections, Intraventricular; Male; Methylhistidines; Narcotic Antagonists; Oxidopamine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympatholytics; Synapses; Thiourea | 2008 |
Modulatory effects of histamine on cat carotid body chemoreception.
Topics: Acetylcholine; Action Potentials; Animals; Carotid Body; Cats; Chemoreceptor Cells; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H3 Antagonists; Hypoxia; In Vitro Techniques; Male; Microscopy, Immunoelectron; Nicotine; Nicotinic Agonists; Piperidines; Pyrilamine; Tyrosine 3-Monooxygenase | 2008 |
Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.
Topics: Animals; Cell Count; Cimetidine; Cyclophosphamide; Cyclosporine; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ear Auricle; Eosinophil Peroxidase; Eosinophils; Gene Expression; Histamine; Histamine Antagonists; Immunoglobulin E; Interferon-gamma; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Picryl Chloride; Piperidines; Pyrilamine; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2009 |
Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice.
Topics: Animals; Anxiety; Benzoxazines; Exploratory Behavior; Hippocampus; Histamine; Histamine Antagonists; Male; Mice; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Pyrilamine; Ranitidine | 2010 |
Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.
Topics: Animals; Butyrophenones; Drug Administration Schedule; Female; Follow-Up Studies; Food; Histamine; Histamine H1 Antagonists; Infusion Pumps; Injections; Motivation; Nicotine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Self Administration; Tobacco Use Disorder | 2011 |
Molecular signaling of pruritus induced by endothelin-1 in mice.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cyclic AMP-Dependent Protein Kinases; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Histamine Antagonists; Mice; Mice, Inbred C57BL; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Kinase C; Pruritus; Pyrilamine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Histamine H1; Signal Transduction; Type C Phospholipases | 2010 |
Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors.
Topics: Allergens; Animals; Benzazepines; Binding, Competitive; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Cell Line; CHO Cells; Cricetinae; Cricetulus; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Humans; In Vitro Techniques; Niacinamide; Ovalbumin; Phthalazines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Recombinant Proteins; Rhinitis, Allergic, Perennial; Transfection | 2011 |
Inverse agonistic activity of antihistamines and suppression of histamine H1 receptor gene expression.
Topics: Animals; Butyrophenones; CHO Cells; Cricetinae; Cricetulus; Drug Inverse Agonism; Gene Expression Regulation; HeLa Cells; Histamine Antagonists; Histamine H1 Antagonists; Humans; Inositol Phosphates; Piperazines; Piperidines; Pyrilamine; Receptors, Histamine H1; RNA, Messenger | 2012 |
Synthesis and dual histamine H₁ and H₂ receptor antagonist activity of cyanoguanidine derivatives.
Topics: Animals; Cimetidine; Guanidines; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Piperidines; Pyrilamine | 2013 |
The novel non-imidazole histamine H3 receptor antagonist DL77 reduces voluntary alcohol intake and ethanol-induced conditioned place preference in mice.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Central Nervous System Depressants; Choice Behavior; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethanol; Histamine Agonists; Histamine H1 Antagonists; Histamine H3 Antagonists; Male; Methylhistamines; Mice, Inbred C57BL; Phenyl Ethers; Piperidines; Pyrilamine; Spatial Behavior; Taste Perception; Volition | 2015 |
The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats.
Topics: Animals; Avoidance Learning; Benzothiazoles; Cholinesterase Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Donepezil; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Histamine H3 Antagonists; Indans; Male; Memory; Memory Disorders; Nootropic Agents; Phenoxypropanolamines; Piperidines; Pyrilamine; Pyrroles; Quinazolines; Random Allocation; Rats, Wistar; Receptors, Histamine H3 | 2016 |
Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats.
Topics: Animals; Anticonvulsants; Benzothiazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine H3 Antagonists; Humans; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Reaction Time; Seizures; Strychnine | 2018 |