pyrilamine has been researched along with orphenadrine in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Churchill, GC; Moore, JB; Schymura, Y; Vasudevan, SR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Flack, WJ; Stern, JS; Treherne, JM; Young, JM | 2 |
| Treherne, JM; Young, JM | 1 |
| Gibson, WJ; Roques, TW; Young, JM | 1 |
9 other study(ies) available for pyrilamine and orphenadrine
| Article | Year |
|---|---|
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Shape-based reprofiling of FDA-approved drugs for the H₁ histamine receptor.
Topics: Animals; Antidepressive Agents; Brain; Calcium; Chlorprothixene; Databases, Chemical; HeLa Cells; High-Throughput Screening Assays; Histamine; Histamine H1 Antagonists; Humans; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Structure-Activity Relationship; United States; United States Food and Drug Administration | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Inhibition by cations of antagonist binding to histamine H1-receptors.
Topics: Animals; Cations; Cell Membrane; Cerebellum; Guinea Pigs; Histamine H1 Antagonists; Lithium; Male; Mercury; Orphenadrine; Pyrilamine; Receptors, Histamine H1; Sodium; Tritium | 1991 |
Inhibition by cations of antagonist binding to histamine H1-receptors: differential effect of sodium ions on the binding of two radioligands.
Topics: Animals; Binding, Competitive; Cadmium; Cations; Cations, Divalent; Cerebellum; Cesium; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Lithium; Male; Orphenadrine; Pyrilamine; Receptors, Histamine H1; Rubidium; Sodium | 1991 |
[3H]-(+)-N-methyl-4-methyldiphenhydramine, a quaternary radioligand for the histamine H1-receptor.
Topics: Animals; Brain; Cerebellum; Electrophoresis; Guinea Pigs; In Vitro Techniques; Isotope Labeling; Male; Orphenadrine; Pyrilamine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Stereoisomerism; Structure-Activity Relationship | 1988 |
Modulation of antagonist binding to histamine H1-receptors by sodium ions and by 2-amino-2-hydroxymethyl-propan-1,3-diol HCl.
Topics: Animals; Cerebellum; Guinea Pigs; HEPES; Histamine H1 Antagonists; Male; Orphenadrine; Pyrilamine; Receptors, Histamine H1; Sodium; Tromethamine | 1994 |