Page last updated: 2024-08-16

pyrilamine and morphine

pyrilamine has been researched along with morphine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199016 (55.17)18.7374
1990's4 (13.79)18.2507
2000's6 (20.69)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Strassburg, CP; Tukey, RH1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Eyre, P; Holroyde, MC1
Bogaert, MG; Buylaert, WA; Willems, JL1
Gupta, VD; Shek, OH1
Roberts, MB; Wong, CL2
Hui, KS; Roberts, MB1
Donin, L; Gori, E; Massi, P; Parolaro, D; Patrini, G; Rubino, T1
Boura, AL; King, RG; Rechtman, MP1
Bugajski, J; Turon, M; Tyton, J1
Guth, PH; Holzer, P; Livingston, EH1
Hurwitz, A; Innis, JD1
Bhandari, P; Bhargava, KP; Chugh, A; Dixit, KS; Gupta, YK; Seth, SD1
Hanig, JP; Hui, FW; Sun, CL1
Livett, BG; Marley, PD1
Dhumal, VR; Gulati, OD; Raghunath, PR; Sivaramakrishna, N1
Chung, YH; Kamei, C; Miyake, H; Tasaka, K1
Bowdy, BD; Crooks, PA; Gillespie, MN; Iwamoto, ET; Reinsel, CN1
Bodhankar, SL; Olubadewo, JO1
Altura, BM; Chand, N1
Abacioğlu, N; Cakici, I; Kanzik, I; Ozmen, R; Tunçtan, B1
Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR1
Djahanguiri, B; Khalilzadeh, A; Zarrindast, MR1
Roohbakhsh, A; Rostami, P; Zarei, M; Zarrindast, MR1
Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR1
Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E1

Reviews

1 review(s) available for pyrilamine and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

28 other study(ies) available for pyrilamine and morphine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Reactivity of isolated bovine mesenteric and hepatic veins to vasoactive agents and specific antigen.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Acetylcholine; Anaphylaxis; Animals; Antigens; Atropine; Cattle; Dopamine; Dose-Response Relationship, Drug; Hepatic Veins; Histamine; Histamine H1 Antagonists; Horses; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesenteric Veins; Methysergide; Morphine; Norepinephrine; Phenylephrine; Pyrilamine; Serotonin; Vasoconstrictor Agents; Vasodilator Agents

1975
Vasodilatation produced by apomorphine in the hindleg of the dog.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:3

    Topics: Animals; Apomorphine; Blood Circulation; Denervation; Dogs; Dopamine; Electric Stimulation; Female; Femoral Artery; Haloperidol; Male; Morphine; Norepinephrine; Phenoxybenzamine; Pyrilamine; Receptors, Dopamine; Vasodilator Agents

1977
Comparison of stability-indicating assay methods: ultraviolet, high pressure liquid chromatography and acid dye.
    American journal of hospital pharmacy, 1976, Volume: 33, Issue:10

    Topics: Chromatography, High Pressure Liquid; Codeine; Coloring Agents; Drug Stability; Ephedrine; Fluorometry; Methods; Morphine; Procaine; Pyrilamine; Spectrophotometry, Ultraviolet; Thiamine

1976
The effects of L-histidine and of specific histamine receptor agonists, on the expression of morphine tolerance and physical dependence in mice.
    Agents and actions, 1976, Volume: 6, Issue:5

    Topics: Animals; Body Weight; Drug Interactions; Drug Tolerance; Female; Histidine; Humans; Male; Metiamide; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Pyrilamine; Reaction Time; Substance Withdrawal Syndrome

1976
The effect of mepyramine on the development of morphine tolerance and physical dependence in mice.
    Life sciences, 1975, Sep-15, Volume: 17, Issue:6

    Topics: Animals; Brain Chemistry; Drug Tolerance; Female; Histamine; Humans; Male; Mice; Morphine; Morphine Dependence; Pyridines; Pyrilamine; Receptors, Drug

1975
The possible role of brain histamine and H1 and H2 receptors in the development of morphine tolerance and physical dependence in mice.
    Agents and actions, 1975, Volume: 5, Issue:5

    Topics: Animals; Drug Tolerance; Female; Histidine; Humans; Male; Metiamide; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Phenobarbital; Pyrilamine; Reaction Time; Receptors, Drug; Substance Withdrawal Syndrome; Time Factors

1975
Further investigations on the antipropulsive effect of centrally administered histamine and its relation with morphine.
    European journal of pharmacology, 1992, Jan-21, Volume: 210, Issue:3

    Topics: Animals; Fasting; Female; Gastrointestinal Motility; Gastrointestinal Transit; Histamine; Injections, Intraventricular; Jejunum; Morphine; Norepinephrine; Oxidopamine; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin

1992
Hypothermia augments non-cholinergic neuronal bronchoconstriction in pithed guinea-pigs.
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Atropine; Azepines; Body Temperature; Bronchoconstriction; Capsaicin; Decerebrate State; Electric Stimulation; Guinea Pigs; Male; Morphine; Ouabain; Pentolinium Tartrate; Propranolol; Pyrilamine; Spinal Cord; Substance P; Sympathetic Nervous System; Tubocurarine

1991
The significance of brain histamine and its receptors in opioid stimulation of the pituitary-adrenocortical activity.
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Adrenal Cortex; Animals; beta-Endorphin; Brain; Cimetidine; Corticosterone; Endorphins; Enkephalin, Leucine-2-Alanine; Histamine; Histidine Decarboxylase; Male; Morphine; p-Methoxy-N-methylphenethylamine; Pituitary Gland; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine

1991
Sensory neurons signal for an increase in rat gastric mucosal blood flow in the face of pending acid injury.
    Gastroenterology, 1991, Volume: 101, Issue:2

    Topics: Animals; Atropine; Ethanol; Gastric Acid; Gastric Mucosa; Male; Morphine; Neurons, Afferent; Pyrilamine; Rats; Rats, Inbred Strains; Regional Blood Flow; Sympathectomy; Tetrodotoxin

1991
Mechanism of hematocrit increase induced by the combined administration of morphine and adriamycin: role of histamine release.
    Toxicology and applied pharmacology, 1987, Sep-30, Volume: 90, Issue:3

    Topics: Animals; Capillary Permeability; Cimetidine; Doxorubicin; Drug Synergism; Hematocrit; Histamine Release; Liver; Male; Mice; Morphine; Pyrilamine

1987
Role of endogenous opioids and histamine in morphine induced emesis.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:1

    Topics: Animals; Cimetidine; Dogs; Endorphins; Histamine; Metiamide; Morphine; Naloxone; Pyrilamine; Vomiting

1989
Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice.
    Neuropharmacology, 1985, Volume: 24, Issue:1

    Topics: Analgesics; Animals; Chlorpheniramine; Cyclizine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Male; Mice; Morphine; Phenothiazines; Pyrilamine

1985
Effects of opioid peptides and morphine on histamine-induced catecholamine secretion from cultured, bovine adrenal chromaffin cells.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: Adrenal Glands; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Endorphins; Epinephrine; Histamine; Morphine; Norepinephrine; Pyrilamine

1986
Analysis of the effects on body temperature of intracerebroventricular injection in anaesthetized dogs of gamma-aminobutyric acid.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Acetylcholine; Aminobutyrates; Animals; Body Temperature; Cerebral Ventricles; Dogs; Epinephrine; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Histamine; Injections; Isoproterenol; Lysergic Acid Diethylamide; Male; Morphine; Norepinephrine; Pentobarbital; Perfusion; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Pyrilamine; Reserpine; Salicylates; Scopolamine; Serotonin; Time Factors

1974
Analgesic effect of histamine induced by intracerebral injection into mice.
    Agents and actions, 1984, Volume: 15, Issue:3-4

    Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time

1984
Leu-enkephalin provokes naloxone-insensitive pulmonary vasoconstriction.
    Life sciences, 1984, Mar-19, Volume: 34, Issue:12

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Lung; Male; Methysergide; Morphine; Naloxone; Pyrilamine; Rats; Rats, Inbred Strains; Vasoconstriction

1984
A study on histamine tachyphylaxis on isolated chick oesophagus.
    Pharmacological research communications, 1982, Volume: 14, Issue:6

    Topics: Acetylcholine; Animals; Atropine; Chickens; Esophagus; Female; Hemicholinium 3; Histamine; Ileum; In Vitro Techniques; Male; Morphine; Physostigmine; Pyrilamine; Serotonin; Tachyphylaxis

1982
Serotonin receptors subserve only contraction in canine and rat pulmonary arteries and veins.
    Artery, 1980, Volume: 7, Issue:3

    Topics: Animals; Atropine; Dogs; Female; In Vitro Techniques; Male; Metiamide; Morphine; Phentolamine; Propranolol; Pulmonary Artery; Pulmonary Veins; Pyrilamine; Rats; Receptors, Serotonin; Serotonin; Vasoconstriction

1980
Role of L-arginine/nitric oxide pathway in the antinociceptive activities of morphine and mepyramine in mice.
    Arzneimittel-Forschung, 2001, Volume: 51, Issue:12

    Topics: Abdomen; Analgesics, Opioid; Animals; Arginine; Benzoquinones; Drug Interactions; Enzyme Inhibitors; Histamine H1 Antagonists; Male; Mice; Morphine; Muscle Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pain Measurement; Pyrilamine; Signal Transduction

2001
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
    European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2

    Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine

2003
Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.
    Behavioural brain research, 2006, Jan-06, Volume: 166, Issue:1

    Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agents; Imidazoles; Injections, Intraventricular; Male; Memory; Mice; Morphine; Morphine Dependence; Pyrilamine; Reaction Time; Thiourea

2006
Intracerebroventricular effects of histaminergic agents on morphine-induced anxiolysis in the elevated plus-maze in rats.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 97, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Drug Interactions; Histamine; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Microinjections; Morphine; Narcotics; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Stereotaxic Techniques

2005
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagonists; Imidazoles; Male; Microinjections; Morphine; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Thiourea

2010
Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:2

    Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Hippocampus; Histamine; Male; Morphine; Naloxone; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2

2011