Page last updated: 2024-08-16

pyrilamine and methapyrilene

pyrilamine has been researched along with methapyrilene in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Ham, NS1
Hill, SJ; Marrian, DH; Sanders, JK; Young, JM1
Thornton, WE1
Cerniglia, CE; Getek, TA; Hansen, EB; Korfmacher, WA1
Klopman, G; Rosenkranz, HS1
Kovatch, RM; Lijinsky, W1
Clive, D; Hozier, JC; Sawyer, JR; Turner, NT; Woolley, JL1
Eisenbrand, G; Habs, M; Shubik, P1
Holder, CL; Thompson, HC1
Lijinsky, W1
Anderson, NL; Cunningham, ML; Pippin, LL; Wenk, ML1

Reviews

1 review(s) available for pyrilamine and methapyrilene

ArticleYear
Sleep aids and sedatives.
    JACEP, 1977, Volume: 6, Issue:9

    Topics: Bromides; Humans; Hypnotics and Sedatives; Male; Methapyrilene; Nonprescription Drugs; Pyrilamine; Scopolamine; Sleep Wake Disorders

1977

Other Studies

11 other study(ies) available for pyrilamine and methapyrilene

ArticleYear
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Conformational populations for antihistamines and antihypertensives in solution.
    Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:4

    Topics: Antihypertensive Agents; Diphenhydramine; Guanethidine; Guanidines; Histamine H1 Antagonists; Methapyrilene; Molecular Conformation; Pyrilamine; Structure-Activity Relationship; Sympatholytics; Tripelennamine

1976
A convenient synthesis of [3H]mepyramine and certain related [3H]antihistamines.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:10

    Topics: Aminopyridines; Chemical Phenomena; Chemistry; Histamine H1 Antagonists; Isotope Labeling; Methapyrilene; Methods; Pyrilamine; Tripelennamine; Tritium

1978
Direct analysis of microbial extracts containing metabolites of ethylenediamine-type antihistamines via high-performance liquid chromatography-thermospray mass spectrometry.
    Analytical biochemistry, 1990, Feb-15, Volume: 185, Issue:1

    Topics: Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Histamine H1 Antagonists; Mass Spectrometry; Methapyrilene; Molecular Structure; Mucorales; Pyridines; Pyrilamine; Tripelennamine

1990
Methapyrilene: DNA as a possible target.
    Mutation research, 1990, Volume: 245, Issue:4

    Topics: Animals; Carcinogenicity Tests; Carcinogens; DNA Damage; Methapyrilene; Mice; Molecular Structure; Mutagenicity Tests; Mutagens; Pyrilamine; Rats; Structure-Activity Relationship

1990
Carcinogenicity studies of some analogs of the carcinogen methapyrilene in F344 rats.
    Journal of cancer research and clinical oncology, 1986, Volume: 112, Issue:1

    Topics: Aminopyridines; Animals; Female; Histamine H1 Antagonists; Liver Neoplasms; Male; Methapyrilene; Pyridines; Pyrilamine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Structure-Activity Relationship

1986
Methapyrilene is a genotoxic carcinogen: studies on methapyrilene and pyrilamine in the L5178Y/TK +/- mouse lymphoma assay.
    Mutation research, 1987, Volume: 189, Issue:3

    Topics: Aminopyridines; Animals; Biotransformation; Carcinogens; Chromosome Aberrations; Leukemia L5178; Methapyrilene; Mice; Microsomes, Liver; Mutagenicity Tests; Neoplasm Proteins; Preservation, Biological; Pyrilamine; Rats; Thymidine Kinase; Tumor Cells, Cultured; Tumor Stem Cell Assay

1987
Carcinogenicity of methapyrilene hydrochloride, mepyramine hydrochloride, thenyldiamine hydrochloride, and pyribenzamine hydrochloride in Sprague-Dawley rats.
    Journal of cancer research and clinical oncology, 1986, Volume: 111, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Aminopyridines; Animals; Dose-Response Relationship, Drug; Female; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Methapyrilene; Neoplasms, Experimental; Pyridines; Pyrilamine; Rats; Structure-Activity Relationship; Tripelennamine

1986
Trace analysis of the antihistamines methapyrilene hydrochloride, pyrilamine maleate and triprolidine hydrochloride monohydrate in animal feed, human urine and wastewater by high-performance liquid chromatography and gas chromatography with nitrogen-phosp
    Journal of chromatography, 1984, Jan-20, Volume: 283

    Topics: Animal Feed; Chromatography, Gas; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Humans; Methapyrilene; Pyrilamine; Sewage; Triprolidine; Waste Disposal, Fluid

1984
Chronic toxicity tests of pyrilamine maleate and methapyrilene hydrochloride in F344 rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:1

    Topics: Aminopyridines; Animals; Carcinogens; Diet; Dose-Response Relationship, Drug; Female; Liver Neoplasms; Male; Methapyrilene; Pyrilamine; Rats; Rats, Inbred F344; Structure-Activity Relationship; Time Factors

1984
The hepatocarcinogen methapyrilene but not the analog pyrilamine induces sustained hepatocellular replication and protein alterations in F344 rats in a 13-week feed study.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:2

    Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Male; Methapyrilene; Mitochondria, Liver; Proliferating Cell Nuclear Antigen; Protein Biosynthesis; Pyrilamine; Pyrimidines; Rats; Rats, Inbred F344

1995