pyrilamine has been researched along with jnj 7777120 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Elz, S; Strasser, A; Wagner, E; Wittmann, HJ | 1 |
| Borrebaeck, CA; Broos, S; Greiff, L; Lindstedt, M; Lundberg, K | 1 |
| Adami, M; Coruzzi, G; de Esch, I; Grandi, D; Guido, N; Leurs, R; Pozzoli, C; Smits, R | 1 |
| Beermann, S; Glage, S; Jonigk, D; Neumann, D; Seifert, R | 1 |
| Ebenezer, AJ; Prasad, K; Rajan, S; Thangam, EB | 1 |
7 other study(ies) available for pyrilamine and jnj 7777120
| Article | Year |
|---|---|
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH(1)R, but low affinity to hH(4)R.
Topics: Histamine H1 Antagonists; Indoles; Models, Molecular; Piperazines; Pyrilamine; Receptors, Histamine H1 | 2011 |
Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells.
Topics: Adult; Allergens; Case-Control Studies; Dendritic Cells; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Indoles; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Piperazines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4; T-Lymphocytes; Transcription, Genetic; Young Adult | 2011 |
Strain-dependent effects of the histamine H₄ receptor antagonist JNJ7777120 in a murine model of acute skin inflammation.
Topics: Animals; Anti-Inflammatory Agents; Croton Oil; Dermatitis; Dermatologic Agents; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Ear, External; Histamine H1 Antagonists; Indoles; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Piperazines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4 | 2012 |
Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cytokines; Drug Administration Schedule; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Histamine Antagonists; Histamine H2 Antagonists; Humans; Immunization; Immunoglobulin E; Indoles; Mice; Mice, Inbred BALB C; Ovalbumin; Piperazines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Time Factors; Treatment Outcome | 2012 |
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells.
Topics: Calcium; Cell Line; Gene Expression Regulation; Gene Silencing; Histamine; Humans; Indoles; Interleukin-1beta; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Piperazines; Pyrilamine; Receptors, Histamine H4; RNA, Small Interfering | 2018 |