pyrilamine has been researched along with indomethacin in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (51.79) | 18.7374 |
| 1990's | 60 (35.71) | 18.2507 |
| 2000's | 17 (10.12) | 29.6817 |
| 2010's | 4 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Caron, G; Ermondi, G | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Iwahashi, M; Matsumoto, R; Matsunaga, Y; Nakai, H; Nambu, F; Okada, Y; Onoda, T; Shimabukuro, A; Toda, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chand, N; Eyre, P | 2 |
| Chand, N; Deroth, L; Eyre, P | 1 |
| Costa Ferreira, JM; Cravo, AC; Gião T Rico, JM; Toscano Rico, J; Zambelli de Almeida, MT | 1 |
| Barrett-Bee, KJ; Green, LR | 1 |
| Phaily, S; Senior, J | 1 |
| Al-Haboubi, HA; Zeitlin, IJ | 1 |
| Lewis, GP; Mangham, BA | 1 |
| Denborough, MA; Mitchell, HW | 1 |
| Burleigh, DE; D'Mello, A; Parks, AG | 1 |
| Goyal, RK; Rattan, S | 1 |
| Buckner, CK; Hand, JM | 1 |
| Mølster, A; Raugstad, TS; Svanes, K; Søreide, O | 1 |
| Lindquist, O; Saldeen, T; Sandler, H | 1 |
| Håkanson, R; Wallengren, J | 1 |
| Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M | 1 |
| Andersson, RG; Grundström, N; Hammarström, S; Lindström, EG | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Bailly, DA; Gruetter, CA; Stewart, NL; Szarek, JL | 1 |
| Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
| Drazen, JM; Shore, SA | 2 |
| Chan, CC; Foster, A | 1 |
| Franz, DR; Robinson, CP | 1 |
| Ikeda, S; Kawasaki, A; Murakata, S; Nambu, F; Okegawa, T; Omawari, N; Sawada, M; Shiraji, T | 1 |
| Adelstein, RS; Corson, MA; Schoenberg, M; Sellers, JR | 1 |
| McWade, D; Prior, T; Rangachari, PK | 1 |
| Bendele, AM; Fleisch, JH; Wong, WS | 1 |
| Braquet, P; Carrier, J; Jancar, S; Sirois, MG; Sirois, P | 1 |
| Knight, DA; Phillips, MJ; Stewart, GA; Thompson, PJ | 1 |
| Kontny, M; LaPlante, AM; Lazer, ES; Letts, LG; Wegner, CD; Wolyniec, WW | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Ikeda, S; Kawasaki, A; Nambu, F; Okegawa, T; Omawari, N; Sawada, M; Yube, N | 1 |
| Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y | 1 |
| Krell, RD; McCarthy, M | 1 |
| Cooke, HJ; Fertel, R; Su, HC; Wang, YZ | 1 |
| Barnes, PJ; Belvisi, MG; Stretton, CD | 1 |
| Farina, PR; Graham, AG; Lazer, ES; Wegner, CD; Wong, HC | 1 |
| Chiossone, DC; Simon, PL; Smith, PL | 1 |
| Crowell, RE; Reed, WP; Van Epps, DE | 2 |
| Durham, SK; Selig, WM; Tocker, JE; Welton, AF | 1 |
| Montaño, LM; Segura, P; Selman, M; Vanda, B; Vargas, MH | 1 |
| Nurko, S; Rattan, S | 1 |
| Regal, JF | 1 |
| Feniuk, W; Humphrey, PP; Trevethick, MA | 1 |
| Castro, GA; Russell, DA | 1 |
| Hirasawa, N; Kamo, I; Tsurufuji, S | 1 |
| Maggi, CA; Meli, A; Patacchini, R; Rovero, P | 1 |
| Buck, M; Goswami, S; Marom, Z; Schachter, EN; Witek, T | 1 |
| Hirao, T; Kohno, H; Konno-Amano, S; Mori, H; Sato, Y | 1 |
| Godfraind, T; Schoeffter, P | 2 |
| Chahl, LA; Fyfe, MC | 1 |
| Luck, W; Simmet, T | 1 |
| Dailey, RA; Hall, JA; Lewis, PE; Meisterling, EM | 1 |
| Fujiwara, M; Yokotani, K | 1 |
| Gupta, S; Katiyar, JC; Patnaik, GK; Srimal, RC | 1 |
| Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM | 1 |
| Aharony, D; Redkar-Brown, DG | 1 |
| Deffebach, ME; Salonen, RO; Webber, SE; Widdicombe, JG | 1 |
| Charette, L; Denis, D; Jones, TR | 1 |
| Nishimura, H; Yamaguchi, K | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S | 1 |
| Ozer, A; Tuğrul, L | 1 |
| Hansson, G; Jodal, M; Karlström, L; Lundgren, O | 1 |
| Austen, KF; Corey, EJ; Drazen, JM; Israel, E; Lee, TH; Leitch, AG; Lewis, RA; Robinson, DR | 1 |
| Austen, KF; Corey, EJ; Drazen, JM; Israel, E; Lee, TH; Leitch, AG; Lewis, RA; Ravalese, J; Robinson, DR | 1 |
| Hirose, K; Hori, Y; Jyoyama, H; Katori, M; Takagi, M; Yamada, K | 1 |
| Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD | 1 |
| Fujiki, H; Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugimura, T; Takahashi, C; Tsurufuji, S; Watanabe, M | 1 |
| Conder, GA; Elfring, G; Griffin, RL; Oostveen, JA; Richards, IM | 1 |
| Bennett, A; Capasso, F; Mascolo, N; Parkinson, N; Romano, V | 1 |
| Aihara, H; Hongoh, K; Kurachi, M; Watanabe, A | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Harvey, MH; Reber, HA; Wedgwood, KR | 1 |
| Bell, RL; Regal, JF | 1 |
| Cirino, M; Letts, LG | 1 |
| Hugli, TE; Marceau, F | 2 |
| Jones, TR; Masson, P | 1 |
| Baird, AW; Cuthbert, AW; Pearce, FL | 1 |
| Christensen, J; Percy, WH | 1 |
| Clay, TP; Miller, P; Stead, H | 1 |
| Hirasawa, N; Ohuchi, K; Tsurufuji, S; Watanabe, M | 1 |
| Ferreira, SH; Vargaftig, BB | 1 |
| Bartlet, AL | 1 |
| Cade, JF; Clancy, RL; Pain, MC; Walker, SE | 1 |
| Owen, DA; Pipkin, MA; Raval, P; Woodward, DF | 1 |
| Hoffman, LH; Hoos, PC | 1 |
| Black, J; Shaw, J; Vincenc, K | 1 |
| Barletta, M; Vemulapalli, S | 1 |
| Biggs, DF; Peterson, MA | 1 |
| Bach, MK; Bloor, CM; Hugli, TE; Stimler, NP | 1 |
| Thomas, G | 1 |
| Bookstaff, RC; Katz, LB; Peterson, RE; Theobald, HM | 1 |
| Izutsu, KT; Siegel, IA; Sproat, R; Yoda, W | 1 |
| Collier, HO; Gardiner, PJ | 1 |
| Gill, CA; Wasserman, MA; Weichman, BM; Woodward, DF | 1 |
| Chiou, GC; Miyano, K | 1 |
| Bloor, CM; Erickson, BW; Huey, R; Hugli, TE | 1 |
| Bloor, CM; Huey, R; Hugli, TE | 1 |
| Bloor, CM; Hugli, TE; Stimler, NP | 1 |
| Bemis, KG; Fleisch, JH; Rinkema, LE | 1 |
| Benveniste, J; Bonnet, J; Page, CP; Paul, W; Pfister, A; Pirotzky, E; Roubin, R | 1 |
| Borda, ES; Cremaschi, GA; Genaro, AM; Sales, ME | 1 |
| Nakajima, K | 1 |
| Burka, JF; Paterson, NA | 1 |
| Gerritsen, ME; Lederis, KP; Morgan, DO; Parks, TP; Printz, MP | 1 |
| Andersson, P | 1 |
| Rand, MJ; Story, DF; Wong-Dusting, HK | 1 |
| Mehrotra, PK | 1 |
| Yoffe, JR | 1 |
| Evans, TW; Griffiths, MJ; MacAllister, RJ; Messent, M | 1 |
| Davison, JS; Mathison, R | 1 |
| Krasnopolsky, L; Lee, JG; Levin, RM; Longhurst, PA; Wein, AJ | 1 |
| Buckner, CK; Conklin, R; Doran, O; Fishleder, RI; Graziano, FM; Will, JA | 1 |
| Aibara, S; Mori, M; Tsukada, W | 1 |
| Bianco, S; Bolla, M; Folco, G; Mezzetti, M; Sala, A; Santinelli, E; Sestini, P | 1 |
| Damas, J; Remacle-Volon, G; Sampaio, CA; Souza Pinto, JC | 1 |
| Brideau, C; Chan, CC; Ho, E; Rodger, IW; Savoie, C; Tousignant, C | 1 |
| Dalton, TK; Harris, AH; Hunt, WA; Joseph, JA; Kandasamy, SB; Rabin, BM | 1 |
| Katori, M; Kawamura, M; Ohwada, T; Shindo, M; Sugimoto, K | 1 |
| Inoue, K; Kakutani, M; Kudo, I; Murakami, M; Okamoto, H | 1 |
| Cheung, LY; Darnell, MP; Wood, JG | 1 |
| Arakawa, H; Hayes, J; Kawikova, I; Löfdahl, CG; Lötvall, J; Morikawa, A; Skoogh, BE | 1 |
| Adams, GK; Kelly, LJ; Undem, BJ | 1 |
| Enzan, K; Inaba, H; Shouji, K; Yoshioka, N | 1 |
| Canton, M; Gully, D; Kitabgi, P; Le Fur, G; Lespy, L; Maffrand, JP; Rostène, W | 1 |
| Buck, MG; Goswami, S; Maayani, S; Marom, Z; Rienzi, N; Schachter, EN; Zuskin, E | 1 |
| Asari, Y; Katori, M; Majima, M; Ohwada, T; Sugimoto, K | 1 |
| Búrigo, AC; Calixto, JB; Medeiros, YS | 1 |
| Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A | 1 |
| Myers, AC; Riccio, MM; Undem, BJ | 1 |
| Amann, R; Donnerer, J; Peskar, BA; Schuligoi, R | 1 |
| Burchardt, ER; Müller-Peddinghaus, R | 1 |
| Fu, LW; Longhurst, JC; Pan, HL | 1 |
| Fujita, M; Kawabata, K; Nakagawa, N; Ohno, H; Takeda, H; Yonetomi, Y | 1 |
| Barnes, PJ; Dupont, LJ; Mak, JC; Pype, JL; Verleden, GM | 1 |
| Goswami, S; Maayani, S; Rienzi, N; Schachter, EN; Zuskin, E | 1 |
| Atwood, L; James, C; Morris, GP; Vanner, S | 1 |
| Allescher, HD; Hahn, A; Huber, A; Neumayer, N | 1 |
| Miller, DJ; O'Dowd, A | 1 |
| Takami, M; Tsukada, W | 1 |
| Al-Rashood, KA; Al-Sayed, MI; Bakheet, DM; El Tahir, KE; El-Obeid, HA | 1 |
| Kohno, S; Miyake, I; Nabe, T; Yamamura, H | 1 |
| Glatzle, J; Grundy, D; Kreis, ME; Müller, M; Zittel, TT | 1 |
| Al Obaid, AR; Al Rasheed, NM; Al Sayed, MI; Al Zuhair, HH; Fatani, AJ | 1 |
| Harvima, IT; Harvima, RJ; Horsmanheimo, M; Saarinen, JV | 1 |
| Ghosh, AK; Hirasawa, N; Ohuchi, K | 1 |
| Jørgensen, H; Kjaer, A; Knigge, U; Kristoffersen, U; Madsen, K; Toftegaard, C; Warberg, J | 1 |
| Barbosa, AM; Cogo, JC; do Amaral, RO; Hyslop, S; Teixeira, CF | 1 |
| Bon, C; Cruz-Höfling, MA; Ferreira de Araújo, PM; Guimarães, AQ; Lôbo de Araújo, A | 1 |
| Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
| Lai, YL; Lin, CH | 1 |
| Tsuruki, T; Yoshikawa, M | 1 |
| Carlos, D; de Paula, L; Faccioli, LH; Malheiro, A; Santos, WF | 1 |
| Green, C; Hewlett, E; Hughes, M; Padgett, D; Schwartz, L; Tessier, J; Zhao, W | 1 |
| Adner, M; Dahlén, SE; Fuchs, B; Karlsson, L; Nilsson, GP; Rao, NL; Riley, JP; Sjöberg, L | 1 |
2 review(s) available for pyrilamine and indomethacin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
Vascular actions of leukotrienes.
Topics: Aminophylline; Animals; Atropine; Blood Platelets; Blood Vessels; Capillary Permeability; Cimetidine; Guanethidine; Hexamethonium Compounds; Humans; Indomethacin; Methysergide; Muscle Contraction; Muscle, Smooth, Vascular; Propranolol; Pyrilamine; Regional Blood Flow; Skin; SRS-A; Vasoconstriction | 1985 |
2 trial(s) available for pyrilamine and indomethacin
| Article | Year |
|---|---|
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A | 1991 |
Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects of leukotriene C4 and prostaglandin D2.
Topics: Administration, Cutaneous; Adolescent; Adult; Allergens; Animals; Anti-Allergic Agents; Cattle; Cyclooxygenase Inhibitors; Female; Humans; Hypersensitivity, Immediate; Indoles; Indomethacin; Leukotriene Antagonists; Leukotriene C4; Male; Masoprocol; Middle Aged; Phenylcarbamates; Prostaglandin D2; Pyrilamine; Skin Tests; Sulfonamides; Tosyl Compounds | 2001 |
164 other study(ies) available for pyrilamine and indomethacin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Discovery of selective indole-based prostaglandin D₂ receptor antagonist.
Topics: Animals; Capillary Permeability; CHO Cells; Conjunctiva; Cricetinae; Cricetulus; Drug Discovery; Guinea Pigs; Humans; Indoles; Receptors, Immunologic; Receptors, Prostaglandin | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Atypical (relaxant) response to histamine in cat bronchus.
Topics: Airway Resistance; Animals; Bronchi; Burimamide; Carbachol; Cats; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Male; Metiamide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propranolol; Pyrilamine; Trachea | 1977 |
Pharmacology of Schultz-Dale reaction in canine lung strip in vitro: possible model for allergic asthma.
Topics: Anaphylaxis; Animals; Asthma; Autacoids; Disease Models, Animal; Dogs; Female; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Lung; Male; Metiamide; Pyrilamine | 1979 |
[Effects of colchicine and of emetine on capillary permeability].
Topics: Animals; Capillary Permeability; Colchicine; Emetine; Extremities; Indomethacin; Male; Methysergide; Pyrilamine; Rats | 1975 |
The relationship between prostaglandin release and lung c-AMP levels during anaphylaxis in the guinea-pig.
Topics: Anaphylaxis; Animals; Burimamide; Cyclic AMP; Guinea Pigs; Histamine; Immunization; Indomethacin; Isoproterenol; Lung; Ovalbumin; Polyphloretin Phosphate; Propranolol; Prostaglandins E; Prostaglandins F; Pyrilamine; Serotonin | 1975 |
Modification of oestrogen-induced uterine hyperaemia by drugs in the ovariectomized rat.
Topics: Animals; Aprotinin; Blood Flow Velocity; Castration; Cellulose; Estradiol; Female; Indomethacin; Kallikreins; Phenylpropionates; Pyrilamine; Rats; Regional Blood Flow; Uterus | 1978 |
The actions of cimetidine, mepyramine, indomethacin and aprotinin (Trasylol) on the inflammatory response in adjuvant rats [proceedings].
Topics: Aminopyridines; Animals; Aprotinin; Arthritis; Arthritis, Experimental; Cimetidine; Guanidines; Indomethacin; Male; Pyrilamine; Rats | 1979 |
Changes in blood flow and mediator content of rabbit skin grafts.
Topics: Animals; Histamine; Indomethacin; Prostaglandins; Pyrilamine; Rabbits; Regional Blood Flow; Skin; Skin Transplantation; Time Factors; Transplantation, Autologous | 1978 |
Anaphylaxis in guinea-pig peripheral airways in vitro.
Topics: Anaphylaxis; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Pyrilamine; SRS-A; Trachea | 1979 |
Responses of isolated human internal anal sphincter to drugs and electrical field stimulation.
Topics: Adenosine Triphosphate; Anal Canal; Ascorbic Acid; Autonomic Agents; Electric Stimulation; Humans; Indomethacin; Muscle Contraction; Piperazines; Prostaglandins; Pyrilamine; Receptors, Adrenergic; Receptors, Cholinergic; Tetrodotoxin; Tosyl Compounds | 1979 |
Effect of bovine pancreatic polypeptide on the opossum lower esophageal sphincter.
Topics: Animals; Atropine; Blood Pressure; Cattle; Dose-Response Relationship, Drug; Esophagogastric Junction; Female; Gastrointestinal Motility; Indomethacin; Male; Manometry; Methysergide; Opossums; Pancreatic Polypeptide; Phentolamine; Pyrilamine; Tetrodotoxin | 1979 |
Effects of selected antagonists on ovalbumin-induced contraction of tracheal strips isolated from the actively sensitized guinea-pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Barium; Guinea Pigs; In Vitro Techniques; Indomethacin; Ovalbumin; p-Methoxy-N-methylphenethylamine; Phenoxybenzamine; Pyrilamine; Trachea | 1979 |
Spasmolytic action of histamine in airway smooth muscle of horse.
Topics: Animals; Atropine; Bronchi; Burimamide; Cimetidine; Histamine; Horses; In Vitro Techniques; Indomethacin; Metiamide; Muscle Contraction; Muscle, Smooth; Propranolol; Pyrilamine; Respiratory System; Trachea | 1978 |
Release of inflammatory mediators into the gastric wall of rats with acute acetic acid induced ulcer.
Topics: Acetates; Acute Disease; Animals; Capillary Permeability; Gastric Mucosa; Gastritis; Indomethacin; Male; Methysergide; Pyrilamine; Rats; Serum Albumin, Radio-Iodinated; Stomach Ulcer | 1978 |
Pulmonary damage following pulmonary microembolism in the dog. Effect of various types of treatment.
Topics: Animals; Aspirin; Calcium; Cyclohexanecarboxylic Acids; Dogs; Female; Indomethacin; Lung; Male; Methylprednisolone; Methysergide; Microcirculation; Phenoxybenzamine; Polyphloretin Phosphate; Pulmonary Edema; Pulmonary Embolism; Pyrilamine; Reserpine; Thrombin; Tranexamic Acid; Vascular Resistance | 1976 |
Effects of capsaicin, bradykinin and prostaglandin E2 in the human skin.
Topics: Adult; Axons; Bradykinin; Capsaicin; Dinoprostone; Dose-Response Relationship, Drug; Humans; Indomethacin; Inflammation; Lidocaine; Middle Aged; p-Methoxy-N-methylphenethylamine; Pyrilamine; Skin; Substance P; Tachyphylaxis; Time Factors; Vasodilation | 1992 |
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve | 1992 |
Relationship between histamine, lipoxygenase and cyclooxygenase products in antigen-induced contraction in guinea-pig tracheal tube preparations.
Topics: Animals; Antigens; Eicosanoids; Epithelium; Female; Guinea Pigs; Histamine; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Muscle Contraction; Muscle, Smooth; Propionates; Pyrilamine; Quinolines; Trachea | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Histamine H1-receptors mediate endothelium-dependent relaxation of rat isolated pulmonary arteries.
Topics: Animals; Cimetidine; Endothelium, Vascular; Histamine; Indomethacin; Male; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Pulmonary Artery; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Vasodilation | 1992 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
Relative bronchoconstrictor activity of neurokinin A and neurokinin A fragments in guinea pigs.
Topics: Amino Acid Sequence; Animals; Atropine; Bronchoconstrictor Agents; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Indomethacin; Infusions, Intravenous; Male; Molecular Sequence Data; Neprilysin; Neurokinin A; Peptide Fragments; Pyrilamine | 1991 |
Peptide leukotriene involvement in pulmonary eosinophil migration upon antigen challenge in the actively sensitized guinea pig.
Topics: Animals; Bronchial Hyperreactivity; Cell Movement; Cimetidine; Eosinophils; Guinea Pigs; Indomethacin; Leukotrienes; Male; Ovalbumin; Propionates; Pyrilamine; Quinolines; Receptors, Immunologic; Receptors, Leukotriene | 1991 |
Effects of palytoxin on guinea pig tracheal strips.
Topics: Acrylamides; Airway Resistance; Animals; Atropine; Calcium; Cnidarian Venoms; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Ouabain; Potassium; Pyrilamine; Sodium; Solutions; Trachea; Verapamil | 1991 |
OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Acrylates; Anaphylaxis; Animals; Bordetella pertussis; Cyclooxygenase Inhibitors; Guinea Pigs; Histamine Release; Immunization; Indomethacin; Male; Methacrylates; Pulmonary Alveoli; Pyrilamine; Thromboxane B2 | 1990 |
Substance P contracts bovine tracheal smooth muscle via activation of myosin light chain kinase.
Topics: Animals; Atropine; Calcium; Cattle; Enzyme Activation; Glycopeptides; In Vitro Techniques; Indomethacin; Ketanserin; Kinetics; Masoprocol; Muscle Contraction; Muscle, Smooth; Myosin Subfragments; Myosin-Light-Chain Kinase; Peptide Mapping; Phosphorylation; Potassium Chloride; Prazosin; Propranolol; Pyrilamine; Substance P; Trachea | 1990 |
Epithelial and mucosal preparations from canine colon: responses to substance P.
Topics: Animals; Atropine; Chlorides; Colon; Culture Techniques; Dogs; Electrophysiology; Epithelium; Female; Indomethacin; Intestinal Mucosa; Ion Channels; Male; Pyrilamine; Substance P; Synaptic Transmission; Tetrodotoxin | 1990 |
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Interactions; Guinea Pigs; Histamine; Hydroxyurea; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A | 1992 |
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; Indomethacin; Lactones; Male; Methysergide; Peritoneal Cavity; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains | 1991 |
The interaction of acetylcholine and histamine on human bronchial smooth muscle contraction.
Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Pyrilamine | 1991 |
BI-L-239, a 5-lipoxygenase inhibitor, blocks inhaled antigen-induced airway hyperresponsiveness in conscious guinea pigs.
Topics: Administration, Inhalation; Airway Resistance; Animals; Antigens; Bronchoconstriction; Guinea Pigs; Indomethacin; Lipoxygenase Inhibitors; Male; Methacholine Compounds; Ovalbumin; Phenols; Pyrilamine; Respiratory Hypersensitivity | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Inhibition of endothelin-induced bronchoconstriction by OKY-046, a selective thromboxane A2 synthetase inhibitor, in guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chromones; Endothelins; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Male; Methacrylates; Pyrilamine; Thromboxane B2; Thromboxane-A Synthase | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
Histamine augments colonic secretion in guinea pig distal colon.
Topics: 2-Chloroadenosine; Animals; Bradykinin; Bumetanide; Chlorides; Cimetidine; Colon; Dinoprostone; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; In Vitro Techniques; Indomethacin; Kinetics; Male; Masoprocol; Muscle, Smooth; Piroxicam; Pyrilamine; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Bombesin-induced bronchoconstriction in the guinea pig: mode of action.
Topics: Animals; Azepines; Blood Pressure; Bombesin; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Trachea; Triazoles | 1991 |
Effect of structure on potency and selectivity in 2,6-disubstituted 4-(2-arylethenyl)phenol lipoxygenase inhibitors.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Blood Platelets; Bronchodilator Agents; Cyclooxygenase Inhibitors; Guinea Pigs; Humans; Indicators and Reagents; Indomethacin; Kinetics; Leukocytes; Leukotrienes; Lipoxygenase Inhibitors; Lung; Molecular Structure; Phenols; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiratory Function Tests; Structure-Activity Relationship | 1990 |
Interleukin-1: effects on rabbit ileal mucosal ion transport in vitro.
Topics: Animals; Atropine; Calcimycin; Calcium; Chlorides; Electrophysiology; In Vitro Techniques; Indomethacin; Interleukin-1; Intestinal Absorption; Intestinal Mucosa; Lipopolysaccharides; Prostaglandins; Pyrilamine; Rabbits; Recombinant Proteins; Sodium; Tetrodotoxin | 1990 |
Responses of isolated pulmonary arteries to the C5a anaphylatoxin.
Topics: Anaphylatoxins; Animals; Complement C5a; Cyclooxygenase Inhibitors; Endothelium, Vascular; Female; Histamine Antagonists; In Vitro Techniques; Indomethacin; Male; Pulmonary Artery; Pyrilamine; Rabbits; Rest; Vasoconstriction | 1990 |
Phospholipase A2-induced pulmonary and hemodynamic responses in the guinea pig. Effects of enzyme inhibitors and mediators antagonists.
Topics: Animals; Azepines; Blood Pressure; Bronchi; Bronchoalveolar Lavage Fluid; Dexamethasone; Enzyme Inhibitors; Guinea Pigs; Humans; Indazoles; Indomethacin; Lung; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pressure; Propranolol; Pyrilamine; SRS-A; Trachea; Triazoles | 1990 |
Pharmacological characterization of mediators and vagal influence in the acute allergic bronchoconstriction in guinea pigs.
Topics: Adenosine; Animals; Bronchoconstriction; Dexamethasone; Diethylcarbamazine; Dipyridamole; Eicosanoic Acids; Female; Guinea Pigs; Histamine; Indomethacin; Male; Neural Pathways; Ovalbumin; Pyrilamine; Respiratory Hypersensitivity; Vagotomy; Vagus Nerve | 1990 |
Role of neuropeptide Y in opossum internal anal sphincter.
Topics: Anal Canal; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guanethidine; Indomethacin; Lumbosacral Plexus; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Neuropeptide Y; Opossums; Pyrilamine; Rectum; Reference Values; Tetrodotoxin | 1990 |
IgG vs IgE: mediators of antigen-induced guinea pig lung parenchymal contraction.
Topics: Animals; Antigens; Atropine; Chromones; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lung; Male; Muscle Contraction; Pyrilamine; SRS-A | 1985 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; Dinoprost; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Propranolol; Prostaglandins F; Pyrilamine; Serotonin; Serotonin Antagonists; Swine; Vena Cava, Inferior | 1986 |
Immunological regulation of colonic ion transport.
Topics: Animals; Antigens, Helminth; Bradykinin; Colon; Dinoprostone; Electric Conductivity; Evoked Potentials; Furosemide; Guinea Pigs; Histamine Release; Indomethacin; Jejunum; Male; Pyrilamine; Quinacrine; Reference Values; Tetrodotoxin; Trichinella; Trichinellosis | 1989 |
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Lung Compliance; Male; Muscle Contraction; Pyrilamine; Respiratory Physiological Phenomena; Respiratory System; Substance P | 1989 |
Analysis of the effects of cyclooxygenase and lipoxygenase inhibitors on leukocyte accumulation in the inflammatory site.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Cimetidine; Cyclooxygenase Inhibitors; Diclofenac; Histamine Release; Indomethacin; Inflammation; Leukocytes; Lipoxygenase Inhibitors; Propionates; Pyrilamine | 1989 |
The hamster isolated trachea: a new preparation for studying NK-2 receptors.
Topics: Animals; Atropine; Cricetinae; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Pyrilamine; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Tachykinins; Thiorphan; Trachea | 1989 |
The effect of cotton bract extract on respiratory glycoconjugate secretion from human airways in vitro.
Topics: Bronchi; Cimetidine; Culture Techniques; Dose-Response Relationship, Drug; Glycoconjugates; Gossypium; Histamine Release; Humans; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Mucous Membrane; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Pyrilamine | 1989 |
Passive air-pouch anaphylaxis in rats. II. Pharmacological characterization.
Topics: Adult; Air; Anaphylaxis; Animals; Capillary Permeability; Chromones; Cromolyn Sodium; Dexamethasone; Dinoprostone; Exudates and Transudates; Histamine Release; Humans; Immunization, Passive; Indomethacin; Isoproterenol; Ketotifen; Masoprocol; Models, Biological; ortho-Aminobenzoates; Pyrilamine; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Development; Muscle, Smooth; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Pyrilamine; Saphenous Vein | 1989 |
Responses of isolated pulmonary arteries to synthetic peptide F-Met-Leu-Phe.
Topics: Animals; Benzofurans; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Male; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Pyrilamine; Rabbits | 1989 |
Mediators of the plasma extravasation response to silver nitrate in the rat skin, subplantar region and ankle joint.
Topics: Alprostadil; Animals; Bradykinin; Histamine; Indomethacin; Joints; Methysergide; Metiamide; Pyrilamine; Rats; Rats, Inbred Strains; Silver Nitrate; Skin | 1989 |
H1-antihistamines and calmodulin antagonists inhibit the ionophore A23187-induced eicosanoid formation by human leukocytes.
Topics: Astemizole; Benzimidazoles; Calcimycin; Calcium Channel Blockers; Eicosanoic Acids; Histamine H1 Antagonists; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Masoprocol; Piperazines; Pyrilamine; Reference Values; Sulfonamides; Trifluoperazine | 1989 |
Formation of ovarian follicular cysts and corpora lutea after treatment with antihistamine or indomethacin in prepubertal gilts.
Topics: Aging; Animals; Cimetidine; Female; Follicular Phase; Histamine; Histamine H1 Antagonists; Indomethacin; Luteal Phase; Ovarian Cysts; Ovulation; Prostaglandins; Pyrilamine; Swine | 1989 |
Effects of substance P on cholinergically stimulated gastric acid secretion and mucosal blood flow in rats.
Topics: Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Gastric Acid; Gastric Mucosa; Indomethacin; Male; Phentolamine; Propranolol; Pyrilamine; Rats; Rats, Inbred Strains; Regional Blood Flow; Substance P; Vagus Nerve | 1985 |
Effect of histamine and its antagonists on the course of Nippostrongylus brasiliensis in rats.
Topics: Animals; Histamine; Histamine Antagonists; Indomethacin; Male; Nematode Infections; Nippostrongylus; p-Methoxy-N-methylphenethylamine; Pyrilamine; Rats; Semicarbazides | 1989 |
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil | 1989 |
Histamine receptors in the smooth muscle of human internal mammary artery and saphenous vein.
Topics: Diuretics; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Indomethacin; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Pyridines; Pyrilamine; Receptors, Histamine; Saphenous Vein; Thoracic Arteries | 1989 |
Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198,615.
Topics: Animals; Antigens; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; Pyrilamine; SRS-A; Trachea | 1989 |
Effects of antigen on tracheal circulation and smooth muscle in sheep of different ages.
Topics: Age Factors; Animals; Antigens, Helminth; Ascaris; Asthma; Female; Indomethacin; Male; Muscle Contraction; Pyrilamine; Sheep; Trachea; Vasoconstriction | 1989 |
Leukotriene and anti-IgE induced contractions of human isolated trachea: studies with leukotriene receptor antagonists and a novel 5-lipoxygenase inhibitor.
Topics: Animals; Antibodies, Anti-Idiotypic; Arachidonate Lipoxygenases; Atropine; Benzofurans; Chromones; Goats; Humans; In Vitro Techniques; Indomethacin; Keto Acids; Lipoxygenase Inhibitors; Muscle Contraction; Phenylbutyrates; Pyrilamine; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Sulfones; Trachea | 1988 |
Angiotensin II-induced relaxation of fowl aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Aorta, Abdominal; Chickens; Cimetidine; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Indomethacin; Methysergide; Microscopy, Electron; Muscle, Smooth, Vascular; Ouabain; Proadifen; Propranolol; Pyrilamine; Vasodilation | 1988 |
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin | 1985 |
Contraction induced by (-)-tartaric acid on rat isolated gastric fundus and its inhibition with indomethacin.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Female; Gastric Fundus; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins E; Pyrilamine; Rats; Rats, Inbred Strains; Tartrates | 1985 |
Influence of sodium deoxycholate on morphology, net fluid transport and motility in the small intestine of the rat.
Topics: Animals; Atropine; Deoxycholic Acid; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Perfusion; Pyrilamine; Rats; Rats, Inbred Strains; Terbutaline | 1987 |
The effects of a fish-oil-enriched diet on pulmonary mechanics during anaphylaxis.
Topics: Airway Resistance; Anaphylaxis; Animals; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Indomethacin; Leukotriene B4; Lung; Lung Compliance; Male; Oils; Plethysmography, Whole Body; Premedication; Pyrilamine | 1985 |
Enhancement of plasma levels of biologically active leukotriene B compounds during anaphylaxis in guinea pigs pretreated by indomethacin or by a fish oil-enriched diet.
Topics: Anaphylaxis; Animals; Cattle; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Guinea Pigs; Indomethacin; Leukotriene B4; Lung; Male; Muscle Contraction; Pyrilamine; Thromboxane B2 | 1986 |
Time course analyses of kinins and other mediators in plasma exudation of rat kaolin-induced pleurisy.
Topics: Animals; Bromelains; Captopril; Exudates and Transudates; Histamine; Immunoenzyme Techniques; Indomethacin; Kaolin; Kinins; Male; Methysergide; Pleurisy; Pyrilamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2; Time Factors | 1988 |
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Male; Methysergide; Phthalazines; Pyridazines; Pyrilamine; SRS-A | 1986 |
Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2.
Topics: Animals; Capillary Permeability; Dinoprostone; Edema; Histamine; Indomethacin; Inflammation; Lyngbya Toxins; Methysergide; Neutrophils; Prostaglandins E; Pyrilamine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Role of cyclooxygenase products of arachidonic acid metabolism in Ascaris antigen-induced bronchoconstriction in sensitized dogs.
Topics: Animals; Antigens, Helminth; Arachidonic Acids; Ascaris; Blood Pressure; Chromones; Dogs; Epoprostenol; Heart Rate; Histamine; Indomethacin; Lung; Lung Volume Measurements; Male; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiration; SRS-A | 1988 |
Potentiation by phenolphthalein of the responses of guinea-pig ileum and rat stomach strip to PGE2 and other agonists.
Topics: Animals; Calcium; Dinoprostone; Drug Synergism; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Methysergide; Muscle Contraction; Muscle, Smooth; Phenolphthaleins; Prostaglandins E; Pyrilamine; Rats; Scopolamine; Stomach | 1988 |
Suppression of bronchial response to platelet activating factor following taurine administration.
Topics: Animals; Bronchial Spasm; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A; Taurine | 1987 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Vasoactive drugs, microvascular permeability, and hemorrhagic pancreatitis in cats.
Topics: Animals; Capillary Permeability; Cats; Cimetidine; Drug Synergism; Female; Hemorrhage; Histamine; Indomethacin; Male; Pancreatitis; Prostaglandins E, Synthetic; Pyrilamine | 1987 |
Mediators of C5a-induced bronchoconstriction in the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A | 1987 |
Effects of the C5a anaphylatoxin and its relationship to cyclo-oxygenase metabolites in rabbit vascular strips.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Complement C5; Complement C5a; Epoprostenol; Humans; In Vitro Techniques; Indomethacin; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Rabbits; Radioimmunoassay; Species Specificity; SRS-A; Sulfonamides; Thromboxane B2 | 1985 |
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Blood Pressure; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A; Timolol; Vagotomy | 1985 |
Immediate hypersensitivity reactions in epithelia from rats infected with Nippostrongylus brasiliensis.
Topics: Animals; Chlorides; Chromones; Colon; Cromolyn Sodium; Electric Conductivity; Epithelium; Hypersensitivity, Immediate; Immunoglobulin G; Indomethacin; Mast Cells; Nematode Infections; Nippostrongylus; Pyrilamine; Rats; Sodium; Sulfonamides; Thioxanthenes; Xanthones | 1985 |
Pharmacological characterization of opossum distal colonic muscularis mucosae in vitro.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Female; Histamine; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Contraction; Muscles; Norepinephrine; Opossums; Phentolamine; Propranolol; Pyrilamine; Tetrodotoxin | 1986 |
A lung perfusion technique for the detection of antigenic intrapulmonary bronchoconstriction and its mediation.
Topics: Animals; Antigens; Bronchi; Chlorpheniramine; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Perfusion; Pressure; Pyrazoles; Pyrilamine; Respiratory Hypersensitivity | 1985 |
Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromones; Dexamethasone; Histamine; Indomethacin; Inflammation; Kinetics; Male; Methysergide; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A | 1985 |
Inhibition by non-steroid anti-inflammatory agents of rabbit aorta contracting activity generated in blood by slow reacting substance C.
Topics: Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Atropine; Autacoids; Colon; Dogs; Fatty Acids, Unsaturated; In Vitro Techniques; Indomethacin; Kinetics; Lipoxygenase; Methysergide; Muscle Contraction; Perfusion; Phenylbutazone; Prostaglandins; Pyrilamine; Rabbits; Rats; Stomach; Vascular Resistance; Vasodilator Agents; Venoms | 1974 |
Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations.
Topics: Adenosine; Adenosine Diphosphate; Animals; Animals, Newborn; Chickens; Cyclic AMP; Electric Stimulation; Esophagus; Histamine; In Vitro Techniques; Indomethacin; Methysergide; Muscle Contraction; Neural Conduction; Neurotransmitter Agents; Norepinephrine; Phentolamine; Polyphloretin Phosphate; Propranolol; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Rectum; Scopolamine; Serotonin; Synaptic Transmission; Vagus Nerve | 1974 |
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macrophages; Methysergide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1981 |
Effect of histamine H1- and H2-receptor antagonists, steroidal and non-steroidal anti-inflammatory agents on carrageenin-induced inflammation of the guinea-pig ear.
Topics: Animals; Anti-Inflammatory Agents; Body Temperature; Carrageenan; Cimetidine; Ear; Glucocorticoids; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Inflammation; Male; Pyrilamine; Time Factors | 1982 |
Effect of histamine receptor antagonists and indomethacin on implantation in the rabbit.
Topics: Aminopyridines; Animals; Capillary Permeability; Cimetidine; Drug Combinations; Drug Interactions; Embryo Implantation; Female; Histamine H1 Antagonists; Indomethacin; Pregnancy; Pyrilamine; Rabbits; Uterus | 1983 |
Relaxation and contraction responses to histamine in the human lung parenchymal strip.
Topics: Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; In Vitro Techniques; Indomethacin; Lung; Metiamide; Muscle Contraction; Muscle Relaxation; Potassium Chloride; Pyrilamine | 1984 |
The role of the sympathetic nervous system in the cardiovascular effects of systemically administered gamma-aminobutyric acid.
Topics: Animals; Blood Pressure; Dogs; Electric Stimulation; Female; gamma-Aminobutyric Acid; Ganglionic Blockers; Heart Rate; Hemodynamics; Indomethacin; Injections, Intra-Arterial; Injections, Intravenous; Male; Pyrilamine; Reserpine; Sympathetic Nervous System; Vagus Nerve | 1984 |
The effects of diazoxide on total lung resistance in the anesthetized paralyzed guinea-pig.
Topics: Airway Resistance; Animals; Atropine; Cromolyn Sodium; Diazoxide; Dose-Response Relationship, Drug; Female; Glossopharyngeal Nerve; Guinea Pigs; Histamine Release; Indomethacin; Lung Compliance; Male; Propranolol; Pyrilamine; Receptors, Adrenergic; Receptors, Nicotinic; Vagotomy | 1980 |
Release of leukotrienes from guinea pig lung stimulated by C5ades Arg anaphylatoxin.
Topics: Anaphylatoxins; Animals; Chromatography, High Pressure Liquid; Complement C5; Complement C5a; Cysteine; Guinea Pigs; Histamine Release; Indomethacin; Lung; Muscle Contraction; Peptides; Pyrilamine; SRS-A; Swine | 1982 |
Mechanism of ionophore A23187 induction of plasma protein leakage and of its inhibition by indomethacin.
Topics: Animals; Anti-Bacterial Agents; Blood Proteins; Calcimycin; Cyproheptadine; Dextrans; Dinoprostone; Indomethacin; Male; Prostaglandins E; Pyrilamine; Rats; Skin | 1982 |
Characterization of the enhanced paw edema response to carrageenan and dextran in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.
Topics: Animals; Bradykinin; Carrageenan; Cyproheptadine; Dextrans; Dinoprostone; Dioxins; Drug Interactions; Edema; Histamine; Indomethacin; Male; p-Methoxy-N-methylphenethylamine; Polychlorinated Dibenzodioxins; Prostaglandins E; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1984 |
Prostaglandin activity and sulcular flow in carrageenan-injected gingiva of the dog.
Topics: Animals; Carrageenan; Dinoprostone; Dogs; Drug Evaluation, Preclinical; Gingiva; Gingival Crevicular Fluid; Gingivitis; Indomethacin; Male; Prostaglandins; Prostaglandins E; Pyrilamine; Time Factors | 1984 |
Specific receptors for prostaglandins in airways.
Topics: Animals; Aspirin; Atropine; Bronchi; Cats; Epoprostenol; Female; Guinea Pigs; Histamine; Humans; Indomethacin; Isoproterenol; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Phentolamine; Propranolol; Prostaglandins E; Prostaglandins F; Pyrilamine; Receptors, Cell Surface; Receptors, Prostaglandin; Trachea | 1980 |
The effect of synthetic leukotrienes on tracheal microvascular permeability.
Topics: Animals; Capillary Permeability; Female; Guinea Pigs; Histamine; Indomethacin; Leukotriene E4; Male; Methacholine Chloride; Methacholine Compounds; Pyrilamine; SRS-A; Trachea | 1983 |
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemolysis; Histamine; Indomethacin; Male; Muscle Contraction; Norepinephrine; Peptides; Pyrilamine; Tachyphylaxis | 1984 |
Pharmacological prevention of ocular inflammation induced by lens proteins.
Topics: Aminopyridines; Animals; Catechols; Cimetidine; Crystallins; Disease Models, Animal; Drug Therapy, Combination; Endophthalmitis; Female; Indomethacin; Masoprocol; Pyrilamine; Rabbits | 1984 |
Contraction of guinea pig lung by synthetic oligopeptides related to human C3a.
Topics: Acetylcholine; Animals; Chromones; Complement C3; Complement C3a; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Oligopeptides; Pyrilamine; SRS-A; Tachyphylaxis | 1984 |
Effects of human anaphylatoxins on guinea pig atria.
Topics: Alprostadil; Anaphylatoxins; Animals; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Guinea Pigs; Heart Rate; Histamine; Humans; In Vitro Techniques; Indomethacin; Myocardial Contraction; Peptides; Prostaglandins E; Pyrilamine | 1984 |
C3a-induced contraction of guinea pig lung parenchyma: role of cyclooxygenase metabolites.
Topics: Animals; Aspirin; Complement C3; Complement C3a; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Swine; Zymosan | 1983 |
Production and antagonism of cutaneous vascular permeability in the guinea pig in response to histamine, leukotrienes and A23187.
Topics: Animals; Bradykinin; Calcimycin; Capillary Permeability; Chromones; Guinea Pigs; Histamine; Indomethacin; Injections, Intradermal; Male; Pyrilamine; Receptors, Histamine; Skin; SRS-A | 1984 |
PAF-acether-induced plasma exudation in rat skin is independent of platelets and neutrophils.
Topics: Animals; Blood Platelets; Blood Proteins; Capillary Permeability; Indomethacin; Male; Methysergide; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains; Skin | 1984 |
Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins.
Topics: Animals; Aspirin; Depression, Chemical; Dose-Response Relationship, Drug; Heart Atria; Indomethacin; Isoantibodies; Mice; Mice, Inbred BALB C; Myocardial Contraction; Pyrilamine; T-Lymphocytes; Time Factors | 1983 |
A possible mechanism of vasoactive agents on plasminogen activator release in isolated perfused pig ears.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Dilazep; Dose-Response Relationship, Drug; Drug Synergism; Ear, External; Histamine; In Vitro Techniques; Indomethacin; Papaverine; Perfusion; Plasminogen Activators; Pressure; Pyrilamine; Quinacrine; Swine; Thrombin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1983 |
A comparison of antigen-induced and calcium ionophore A23187 induced contraction of isolated guinea pig trachea.
Topics: Animals; Anti-Bacterial Agents; Antigens; Calcimycin; Calcium; Contracture; Guinea Pigs; Indomethacin; Male; Ovalbumin; Pyrazoles; Pyrilamine; Time Factors; Trachea | 1981 |
A proposed role for prostaglandins in the modulation of the relaxation response to urotensin I in isolated rat arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arteries; Aspirin; Atropine; Dose-Response Relationship, Drug; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Peptides; Propranolol; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains; Urotensins | 1981 |
Effects of inhibitors of anaphylactic mediators in two models of bronchial anaphylaxis in anaesthetized guinea-pigs.
Topics: Anaphylaxis; Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiration | 1982 |
Effects of histamine on the resting and stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.
Topics: Animals; Atropine; Cimetidine; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Indomethacin; Male; Myocardium; Norepinephrine; Phentolamine; Propranolol; Pyrilamine | 1982 |
Effect of some nonsteroidal substances on decidual cell reaction in immature rats.
Topics: Animals; Centchroman; Clomiphene; Decidua; Female; Indomethacin; Pregnancy; Pyrilamine; Rats; Serotonin | 1982 |
Effects of inflammatory agents on endothelial lysosomal fragility and their inhibition by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Bradykinin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Histamine; Humans; Indomethacin; Lysosomes; Prostaglandins E; Pyrilamine | 1981 |
Aminoguanidine selectively inhibits inducible nitric oxide synthase.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Cimetidine; Endothelium, Vascular; Endotoxins; Enzyme Induction; Guanidines; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Phenylephrine; Pulmonary Artery; Pyrilamine; Rats; Rats, Wistar | 1993 |
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections | 1993 |
Effects of the peptide leukotriene receptor antagonist ICI 198,615 on the in vivo and in vitro changes in guinea pig bladder function which occur after sensitization with ovalbumin.
Topics: Animals; Female; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotriene Antagonists; Muscle Contraction; Ovalbumin; Pyrilamine; SRS-A; Urinary Bladder; Urodynamics | 1995 |
Pharmacologic modulation of the influence of the epithelium on immunologic- and nonimmunologic-induced histamine release and contraction in guinea pig superfused tracheal strips.
Topics: Animals; Epithelium; Female; Guinea Pigs; Histamine Release; Hydroxyurea; In Vitro Techniques; Indazoles; Indomethacin; Muscle Contraction; Ovalbumin; Pyrilamine; Trachea; Tubocurarine | 1993 |
Inhibitory effect of DS-4574 on leukotriene- or antigen-induced bronchoconstriction in guinea pigs.
Topics: Animals; Antigens; Asthma; Atropine; Bronchoconstriction; Guinea Pigs; Histamine Release; Immunization; Indomethacin; Leukotriene Antagonists; Leukotriene E4; Male; Pyrilamine; Pyrimidines; SRS-A; Triazoles | 1993 |
Furosemide attenuates bronchial responsiveness to antigen challenge "in vitro".
Topics: Acetophenones; Acetylcholine; Bronchi; Bronchiectasis; Carcinoma, Bronchogenic; Dicarboxylic Acids; Furosemide; Immunoglobulin E; In Vitro Techniques; Indomethacin; Isometric Contraction; Leukotriene Antagonists; Lung Neoplasms; Membrane Proteins; Muscle, Smooth; Pyrilamine; Receptors, Leukotriene; SRS-A; Tetrazoles | 1995 |
Collagenase-induced oedema in the rat paw and the kinin system.
Topics: Animals; Arginine; Azepines; Bradykinin; Collagenases; Edema; Female; Heparin; Hindlimb; Indomethacin; Kallikrein-Kinin System; Ketoprofen; Kininogens; Male; Methysergide; Nitroarginine; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Triazoles | 1995 |
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique.
Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Neurokinin A; Parasympatholytics; Piperidines; Plethysmography; Propionates; Pyrilamine; Quinolines | 1994 |
Exposure to heavy charged particles affects thermoregulation in rats.
Topics: Alpha Particles; Animals; Argon; Body Temperature Regulation; Cimetidine; Helium; Indomethacin; Iron Radioisotopes; Male; Neon; Pyrilamine; Rats; Rats, Sprague-Dawley | 1994 |
Transmigration routes and a delayed systemic hypotension in rats after intraperitoneal injection of endotoxin from Escherichia coli.
Topics: Animals; Body Temperature; Dinoprostone; Endotoxins; Escherichia coli; Exudates and Transudates; Hematocrit; Hypotension; Indomethacin; Injections, Intraperitoneal; Intestines; Male; Methysergide; Peritonitis; Pyrilamine; Rats; Rats, Sprague-Dawley | 1993 |
Role of type II phospholipase A2 in the inflammatory process of carrageenan-induced pleurisy in rats.
Topics: Animals; Antibodies, Monoclonal; Carrageenan; Indomethacin; Inflammation; Male; Phospholipases A; Phospholipases A2; Pleural Effusion; Pleurisy; Pyrilamine; Rats | 1994 |
Adenosine is a mediator of ethanol-induced gastric vasodilation in dogs.
Topics: Adenosine; Animals; Cimetidine; Dogs; Ethanol; Histamine; Indomethacin; Male; Muscle, Smooth; Purinergic Antagonists; Pyrilamine; Regional Blood Flow; Stomach; Theophylline; Vascular Resistance; Vasodilation | 1993 |
Role of arachidonic acid metabolites in airway responses induced by trimellitic anhydride in actively sensitized guinea pigs.
Topics: Airway Resistance; Animals; Arachidonic Acid; Bronchi; Evans Blue; Exudates and Transudates; Guinea Pigs; Immunization; Indazoles; Indomethacin; Ketanserin; Male; Methacrylates; Permeability; Phthalazines; Phthalic Anhydrides; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Thromboxane-A Synthase | 1993 |
Antigen-induced contraction of guinea pig isolated pulmonary arteries and lung parenchyma.
Topics: Animals; Antigens; Dicarboxylic Acids; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Metiamide; Muscle Contraction; Ovalbumin; Pulmonary Artery; Pyrilamine; SRS-A; Vasoconstriction | 1993 |
Inhibition of pulmonary hypertensive response after antigen challenge.
Topics: Animals; Antigens; Benzenesulfonates; Blood Pressure; Bronchoconstriction; Cycloheptanes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Erythrocytes; Histamine; Histamine H1 Antagonists; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Perfusion; Pulmonary Artery; Pyrilamine; Rabbits; Receptors, Thromboxane; Thromboxane A2 | 1995 |
Effect of the neurotensin receptor antagonist SR48692 on rat blood pressure modulation by neurotensin.
Topics: Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Histamine H1 Antagonists; Indomethacin; Injections, Intravenous; Kinetics; Male; Neurotensin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrazoles; Pyrilamine; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Neurotensin; Substance P; Time Factors | 1996 |
Pharmacologic characterization of wool dust extract in isolated guinea pig trachea.
Topics: Air Pollutants, Occupational; Animals; Atropine; Bronchoconstriction; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Leukotriene Antagonists; Male; Occupational Exposure; Pyrilamine; Trachea; Verapamil; Wool | 1995 |
Release site of TNF alpha after intravenous and intraperitoneal injection of LPS from Escherichia coli in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Escherichia coli; Histamine H1 Antagonists; Indomethacin; Injections, Intraperitoneal; Injections, Intravenous; Lipopolysaccharides; Liver; Male; Methysergide; Portal Vein; Prostaglandins; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tumor Necrosis Factor-alpha | 1996 |
Pharmacological profile of rat pleurisy induced by Bothrops jararaca venom.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bothrops; Cell Count; Crotalid Venoms; Cyproheptadine; Dexamethasone; Histamine H1 Antagonists; Histamine Release; Indomethacin; Leukocytes, Mononuclear; Lipoxygenase Inhibitors; Male; Neutrophils; p-Methoxy-N-methylphenethylamine; Pleurisy; Pyrazoles; Pyrilamine; Rats; Serotonin | 1996 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |
Immunomodulation of afferent neurons in guinea-pig isolated airway.
Topics: Action Potentials; Afferent Pathways; Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Pyrilamine; Respiratory System; Time Factors; Vagus Nerve | 1996 |
Release of calcitonin gene-related peptide in cardiac anaphylaxis.
Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Calcitonin Gene-Related Peptide; Cimetidine; Coronary Circulation; Cyclooxygenase Inhibitors; Guinea Pigs; Heart; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Leukotriene C4; Lipoxygenase Inhibitors; Myocardium; Ovalbumin; Pyrilamine; Quinolines; Thromboxane B2 | 1997 |
Antiedematous effects of combination therapies with the leukotriene synthesis inhibitor BAY X 1005 in the archidonic acid-induced mouse ear inflammation test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Disease Models, Animal; Drug Therapy, Combination; Ear; Edema; Female; Histamine H1 Antagonists; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Methysergide; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrilamine; Quinolines; Serotonin Antagonists | 1997 |
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.
Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; Duodenum; Female; Gallbladder; Histamine; Histamine H1 Antagonists; Indomethacin; Ischemia; Male; Methylhistamines; Nerve Fibers; Neural Conduction; Pancreas; Pyrilamine; Receptors, Histamine H1 | 1997 |
Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chromones; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine H1 Antagonists; Indomethacin; Leukotriene Antagonists; Nasal Mucosa; Ovalbumin; Phthalazines; Pyrilamine; Rhinitis, Allergic, Perennial; SRS-A; Thromboxane B2 | 1997 |
Regulation of H1-receptor coupling and H1-receptor mRNA by histamine in bovine tracheal smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indoles; Indomethacin; Maleimides; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; RNA, Messenger; Trachea | 1998 |
Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue.
Topics: Animals; Arachidonic Acids; Atropine; Capsaicin; Cholinergic Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gallic Acid; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Isoxazoles; Latex; Leukotriene Antagonists; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1998 |
Cellular pathways of mast cell- and capsaicin-sensitive nerve-evoked ileal submucosal arteriolar dilations.
Topics: Alprostadil; Animals; Arterioles; Bradykinin; Capsaicin; Cattle; Epoprostenol; Food Hypersensitivity; Guinea Pigs; Ileum; Indomethacin; Lactoglobulins; Mast Cells; Microscopy, Video; Milk; Muscle, Smooth; Neurons; omega-N-Methylarginine; Pyrilamine; Serotonin; Vasodilation | 1998 |
Effect of interleukin-1beta on the ascending and descending reflex in rat small intestine.
Topics: Animals; Cyclooxygenase Inhibitors; Electric Stimulation; Histamine Antagonists; Imidazoles; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-2; Intestine, Small; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscles; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Interleukin-1; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiourea; Tumor Necrosis Factor-alpha | 1998 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketanserin; Methiothepin; Muscle Contraction; Muscle Relaxation; Pyrilamine; Rabbits; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Saphenous Vein; Serotonin Antagonists; Vasoconstrictor Agents; Zinc | 1998 |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase | 1999 |
Studies on the cardiovascular depressant effects of N-ethyl- and N-benzyl-1,2-diphenylethanolamines in the rat: elucidation of the mechanisms of action.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Chloride; Cardiovascular Agents; Cardiovascular Diseases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Histamine H1 Antagonists; Histamine H2 Antagonists; Indomethacin; Male; Pyrilamine; Ranitidine; Rats; Rats, Wistar | 1999 |
Reproducible biphasic cutaneous edema induced by topical and repeated application of antigen in sensitized mice.
Topics: Animals; Antigens; Benzoquinones; Cyclooxygenase Inhibitors; Dermatitis, Allergic Contact; Histamine H1 Antagonists; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Ovalbumin; Pyrilamine; Reproducibility of Results | 2000 |
Mediators of neuronal activation in the rat brainstem following intestinal anaphylaxis.
Topics: Anaphylaxis; Animals; Brain Stem; Chickens; Histamine H1 Antagonists; Immunohistochemistry; Indomethacin; Intestinal Mucosa; Intestines; Male; Neurons, Afferent; Ovalbumin; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Solitary Nucleus | 2000 |
Effects of two newly synthesized analogues of lidocaine on rat arterial blood pressure and heart rate.
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Benzoates; Blood Pressure; Calcium Chloride; Cyproheptadine; Enzyme Inhibitors; Heart Rate; Hexamethonium; Histamine Agonists; Indomethacin; Lidocaine; Male; Monitoring, Physiologic; NG-Nitroarginine Methyl Ester; Pyrilamine; Quinacrine; Ranitidine; Rats; Rats, Wistar; Vasodilator Agents | 2001 |
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Granulation Tissue; Histamine; Histamine Antagonists; Immunohistochemistry; Indoles; Indomethacin; Inflammation; Isoquinolines; Lymphokines; Macrophages, Peritoneal; Male; Maleimides; Naphthalenes; Neovascularization, Pathologic; Piperidines; Protein Kinase C; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H2; RNA, Messenger; Specific Pathogen-Free Organisms; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion.
Topics: Animals; Cimetidine; Cyclooxygenase Inhibitors; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypothalamus; Indomethacin; Lipopolysaccharides; Male; Oxytocin; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Rats; Rats, Wistar; Vasopressins | 2003 |
Pharmacological characterization of mouse hind paw oedema induced by Bothrops insularis (jararaca ilhoa) snake venom.
Topics: Animals; Antivenins; Blood Proteins; Bothrops; Crotalid Venoms; Cyclooxygenase Inhibitors; Cyproheptadine; Dexamethasone; Edema; Enzyme Inhibitors; Hindlimb; Histamine H1 Antagonists; Indomethacin; Lactones; Male; NG-Nitroarginine Methyl Ester; Pyrilamine; Serotonin Antagonists; Sulfones; Time Factors | 2003 |
Pharmacological and histopathological characterization of Bothrops lanceolatus (Fer de lance) venom-induced edema.
Topics: Adrenergic beta-Antagonists; Animals; Antiemetics; Arachidonic Acid; Bothrops; Bradykinin; Cardiovascular Agents; Crotalid Venoms; Dexamethasone; Dose-Response Relationship, Drug; Edema; Edetic Acid; Extremities; Histamine; Histamine H1 Antagonists; Indomethacin; Mast Cells; Methysergide; Pyrilamine; Rats; Rats, Wistar; Serotonin; Time Factors; Vasoconstrictor Agents | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
Mast cell mediators in citric acid-induced airway constriction of guinea pigs.
Topics: Administration, Inhalation; Animals; Bronchoconstriction; Citric Acid; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indoles; Indomethacin; Leukotriene C4; Mast Cells; p-Methoxy-N-methylphenethylamine; Prostaglandins; Pyrilamine; Serotonin | 2005 |
Orally administered FPRL1 receptor agonist peptide MMK-1 inhibits etoposide-induced alopecia by a mechanism different from intraperitoneally administered MMK-1.
Topics: Administration, Oral; Alopecia; Animals; Cimetidine; Disease Models, Animal; Etoposide; Female; Indomethacin; Injections, Intraperitoneal; Male; Peptides; Pyrilamine; Rats; Receptors, Formyl Peptide; Receptors, Lipoxin | 2006 |
Differential modulation of cell recruitment and acute edema in a model of Polybia paulista venom-induced inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Dose-Response Relationship, Drug; Edema; Eosinophils; Histamine H1 Antagonists; Histamine H2 Antagonists; Indoles; Indomethacin; Leukocytes; Male; Neutrophil Infiltration; Peritoneal Cavity; Pyrilamine; Rats; Rats, Wistar; Wasp Venoms | 2006 |
Contributions of histamine, prostanoids, and neurokinins to edema elicited by edema toxin from Bacillus anthracis.
Topics: Animals; Antigens, Bacterial; Aprepitant; Bacillus anthracis; Bacterial Toxins; Capillary Permeability; Celecoxib; Cell Degranulation; Cell Line; Disease Models, Animal; Edema; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Humans; Indomethacin; Injections, Intradermal; Mast Cells; Morpholines; Neurokinin-1 Receptor Antagonists; Prostaglandin Antagonists; Prostaglandins; Pyrazoles; Pyrilamine; Rabbits; Substance P; Sulfonamides; Tachykinins | 2007 |
Mast cell mediators cause early allergic bronchoconstriction in guinea-pigs in vivo: a model of relevance to asthma.
Topics: Acetates; Animals; Asthma; Bronchial Hyperreactivity; Constriction, Pathologic; Cyclopropanes; Disease Models, Animal; Guinea Pigs; Histamine Antagonists; Hypersensitivity; Indomethacin; Leukotriene Antagonists; Lung; Mast Cells; Ovalbumin; Prostaglandin Antagonists; Pyrilamine; Quinolines; Sulfides | 2013 |