Page last updated: 2024-08-16

pyrilamine and histaprodifen

pyrilamine has been researched along with histaprodifen in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bakker, RA; Elz, S; Govoni, M; Leurs, R; Menge, WM; Schunack, W; Smit, MJ; Timmerman, H; van de Wetering, I1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Elz, S; Kramer, K; Leschke, C; Schunack, W1
Bavec, A; Carman-Krzan, M; Schunack, W; Zorko, M1
Bakker, RA; Bruysters, M; Chatelain, P; Gillard, M; Leurs, R; Pertz, HH; Schunack, W; Teunissen, A; Timmerman, H1
Seifert, R; Strasser, A; Striegl, B; Wittmann, HJ1

Other Studies

6 other study(ies) available for pyrilamine and histaprodifen

ArticleYear
Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.
    Journal of medicinal chemistry, 2003, Dec-18, Volume: 46, Issue:26

    Topics: Animals; Binding, Competitive; Cell Line; Chlorocebus aethiops; Genes, Reporter; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Inositol Phosphates; Ligands; NF-kappa B; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship

2003
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Ring-substituted histaprodifen analogues as partial agonists for histamine H(1) receptors: synthesis and structure-activity relationships.
    European journal of medicinal chemistry, 2000, Volume: 35, Issue:1

    Topics: Animals; Aorta; Cyclization; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Ileum; Imidazoles; Male; Muscle Contraction; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Structure-Activity Relationship

2000
Molecular characterization of specific H1-receptor agonists histaprodifen and its Nalpha-substituted analogues on bovine aortic H1-receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:5

    Topics: Animals; Aorta, Thoracic; Binding Sites; Cattle; GTP-Binding Proteins; GTPase-Activating Proteins; Histamine; Histamine Agonists; Male; Protein Binding; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship; Tritium

2003
Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Animals; Binding Sites; Cells, Cultured; Chlorocebus aethiops; COS Cells; DNA Mutational Analysis; Dose-Response Relationship, Drug; Genes, Reporter; Histamine; Histamine Agonists; Mutagenesis, Site-Directed; NF-kappa B; Pyrilamine; Receptors, Histamine H1; Transfection

2004
Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Cloning, Molecular; GTP Phosphohydrolases; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Molecular Sequence Data; Phylogeny; Pyrilamine; Rats; Receptors, Histamine H1; Recombinant Proteins; Sequence Alignment

2008