pyrilamine has been researched along with histamine in 863 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 443 (51.33) | 18.7374 |
| 1990's | 265 (30.71) | 18.2507 |
| 2000's | 119 (13.79) | 29.6817 |
| 2010's | 34 (3.94) | 24.3611 |
| 2020's | 2 (0.23) | 2.80 |
| Authors | Studies |
|---|---|
| Timmerman, H | 1 |
| Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A | 1 |
| Bakker, RA; Booth, RG; Choksi, NY; Leurs, R; Moniri, NH; Nix, WB; Timmerman, H | 1 |
| Bakker, RA; Elz, S; Govoni, M; Leurs, R; Menge, WM; Schunack, W; Smit, MJ; Timmerman, H; van de Wetering, I | 1 |
| Bakker, RA; DeGrip, WJ; DeGroot, HJ; Leurs, R; Ratnala, VR; Swarts, HG; VanOostrum, J | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Bakker, RA; Ballesteros, JA; Bruysters, M; Haaksma, E; Jongejan, A; Leurs, R; Pardo, L | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Clark, RA; Gallin, JI; Kaplan, AP | 1 |
| Ercan, ZS; Türker, RK | 5 |
| Griessen, M; Perrier, CV | 1 |
| Assem, ES | 1 |
| Chipman, P; Glover, WE | 1 |
| Brody, MJ; Powell, JR | 2 |
| Jaques, LB; Wollin, A | 1 |
| Saeki, K; Wake, K; Yamasaki, H | 1 |
| Zoha, MS | 1 |
| Duckworth, JW; Lance, JW; Lord, GD; Mylecharane, EJ | 1 |
| Chand, N; Eyre, P | 5 |
| Duchene-Marullaz, P; Dureng, G; Labrid, C; Moleyre, J | 1 |
| Jones, DG; Kay, AB | 1 |
| Bunce, KT; Parsons, ME | 1 |
| Eyre, P; Hanna, CJ | 1 |
| Sturkie, PD | 1 |
| Kuschinsky, W; Wahl, M | 1 |
| Bruggeman, TM; Davenport, HW; Wood, JG | 1 |
| Sakai, K | 1 |
| Flynn, SB; Owen, DA | 3 |
| Saeki, K; Wake, K; Yokoyama, J | 1 |
| Litt, M | 1 |
| Brown, PA; Brown, TH; Vernikos-Danellis, J | 1 |
| Yamasaki, H | 1 |
| Eyre, P; Holroyde, MC | 2 |
| Cheung, LY; Porterfield, G | 1 |
| Kaliner, M | 2 |
| Grönneberg, R; Hägermark, O; Strandberg, K | 1 |
| Bökesoy, TA; Ercan, ZS; Ersoy, F; Türker, RK; Zengil, H | 1 |
| Behsudi, FM; Bruce, LA; Fawcett, CP | 1 |
| Horisaka, K; Mori, A; Takeuchi, H; Yokoi, I | 1 |
| Becker, M; Malchow, H; Painz, B; Rack, M; Ruoff, HJ; Sewing, KF | 1 |
| Barrett-Bee, KJ; Green, LR | 1 |
| Cooper, A; Jones, D; Major, J; Scholes, P; Walters, M; Wilde, C | 1 |
| Hecht, K; Kranz, D; Poppei, M; Wollenberger, A | 1 |
| Allouche, G; Foussard, C; Parrot, JL; Ruff, F; Santais, MC | 1 |
| Butzheinen, R; Reinhardt, D; Ritter, E; Schümann, HJ | 1 |
| Ganong, WF; Kaplan, S; Richards, GE; Rudolph, C | 1 |
| Sandberg, N | 1 |
| Saxena, PR | 1 |
| Fredericks, CM | 1 |
| Schwartz, JC | 1 |
| Parratt, JR; Sturgess, RM | 1 |
| Lewis, GP; Mangham, BA | 1 |
| Denborough, MA; Mitchell, HW | 1 |
| Gerner, T; Haffner, JF; Norstein, J | 1 |
| Anderson, GF; Van Buren, GA | 1 |
| Riding, GA; Willadsen, P; Wood, GM | 1 |
| Hagen, M; Paegelow, I | 1 |
| Shone, DG; Wright, HP | 1 |
| Harvey, CA; Owen, DA; Shaw, KD | 1 |
| Vohra, MM | 1 |
| Casteels, R; Suzuki, H | 1 |
| Cheng, HC; Munro, NL; Reavis, OK; Woodward, JK | 1 |
| Biggs, DF; Peterson, MA | 1 |
| Foldes, A | 1 |
| Chand, N; DeRoth, L; Eyre, P | 1 |
| Szelenyi, I; Thiemer, K | 1 |
| Nowak, JZ; Pilc, A | 1 |
| Bertaccini, G; Coruzzi, G; Musso, E | 1 |
| Evans, DP; Love, RJ; Rothwell, TL | 1 |
| Ohga, A; Taneike, T | 1 |
| Bertaccini, G; Impicciatore, M; Morini, G | 1 |
| Leid, RW; Musoke, AJ; Williams, JF | 1 |
| Guth, PH; Smith, E | 1 |
| Barkla, DH; Tutton, PJ | 1 |
| Hoffman, WE; Schmid, PG | 1 |
| Bertaccini, G; Coruzzi, G; Vitali, T | 1 |
| Carter, DC; Grossman, MI; Impicciatore, M | 1 |
| Hicks, PE | 1 |
| Gárdos, G; Lassen, UV; Pape, L | 1 |
| Calkins, PJ; Fleisch, JH | 1 |
| Carroll, PR; Glover, WE | 1 |
| Bhargava, KP; Nath, R; Palit, G | 1 |
| Finch, L; Hicks, PE | 2 |
| Giles, RW; Heise, G; Wilcken, DE | 1 |
| Baysal, F | 1 |
| Maśliński, C; Nowak, JZ | 2 |
| Richardson, PD; Withrington, PG | 1 |
| Johnston, BM; Owen, DA | 1 |
| Haye, R; Vegge, T | 1 |
| Bertaccini, G; Grossman, MI; Hansen, D; Impicciatore, M; Mossini, F | 1 |
| Bernauer, W | 1 |
| Cox, B; Green, MD; Lomax, P | 2 |
| Bhargava, KP; Dixit, KS; Palit, G | 1 |
| Phillis, JW; Sastry, BS | 1 |
| Clark, WG; Cumby, HR | 1 |
| Fontagne, J; Godlewski, J; Lechat, P; Loizeau, M; Tissot, M | 1 |
| Corrêa, FM; Graeff, FG | 1 |
| Ruoff, HJ; Sewing, KF | 1 |
| Anttila, P; Lücke, C; Westermann, E | 1 |
| Elder, JB; Ganguli, PC; Gerring, EL; Gillespie, IE; Gregory, H | 1 |
| Grennan, DM | 1 |
| Botting, JH | 1 |
| Black, JW; Owen, DA; Parsons, ME | 1 |
| Broadley, KJ | 1 |
| Dunn, CJ; Willoughby, DA | 1 |
| Sackeyfio, AC | 1 |
| Hui, KS; Roberts, MB | 1 |
| Fozard, JR | 1 |
| Dugan, JJ; Mathé, AA; Yen, SS | 1 |
| Brody, MJ; Christensen, J; de Carle, DJ | 1 |
| Cuthbert, AW; MacVinish, LJ; Pickles, RJ | 1 |
| Chirtel, SJ; Field, RB | 1 |
| Code, CF; Nakaya, N; Tasaka, K | 1 |
| Brandes, LJ; LaBella, FS | 1 |
| Ellis, JL; Undem, BJ | 2 |
| Yang, P | 1 |
| Ruiz, G; WoldeMussie, E | 1 |
| Boura, AL; King, RG; Leitch, IM | 1 |
| Go, K; Namimatsu, A; Okuda, M; Tanimoto, H | 1 |
| Katsoulis, S; Racké, K; Schwörer, H | 1 |
| Darley-Usmar, V; O'Leary, VJ; Payne, AN; Wilkinson, D; Yeadon, M | 1 |
| Bagavandoss, P; Mitchell, MA; Wilks, JW | 1 |
| Jakschik, BA; Ramos, BF; Zhang, Y | 1 |
| Alada, AR; Oyebola, DD | 1 |
| Niimi, N; Noso, N; Yamamoto, S | 1 |
| Cervos-Navarro, J; Dey, PK; Nyberg, F; Sharma, HS | 1 |
| Andersson, RG; Grundström, N; Hammarström, S; Lindström, EG | 1 |
| Cabanie, M; Ebeigbe, AB | 1 |
| Fukuda, Y; Inukai, T; Noguchi, S | 1 |
| Hall, IP | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Bailly, DA; Gruetter, CA; Stewart, NL; Szarek, JL | 1 |
| Dickenson, JM; Hill, SJ | 3 |
| Donin, L; Gori, E; Massi, P; Parolaro, D; Patrini, G; Rubino, T | 1 |
| Anjelkovic, IZ; Collis, CS; Djuric, D; Rosic, M; Segal, MB; Zlokovic, BV | 1 |
| Clarke, CC; Desai, S; Farina, PR; Gundel, RH; Homon, CA; Kinkade, P; Torcellini, CA; Watrous, J; Wegner, CD | 1 |
| Endou, M; Gando, S; Hattori, Y; Kanno, M | 1 |
| Bast, A; Leurs, R; Smit, MJ; Timmerman, H | 1 |
| Ballabeni, V; Barocelli, E; Chiavarini, M; Impicciatore, M; Morini, G; Silva, C; Vitali, T | 1 |
| Godfraind, T; Schoeffter, P | 3 |
| Hikawa, N; Igarashi, T; Ishigatsubo, Y; Kawakami, T; Ohno, S; Okubo, T; Shirai, A; Takenaka, T; Tani, K; Ueda, A | 1 |
| Fukui, H; Inagaki, N; Kanamura, A; Kubo, A; Wada, H | 1 |
| Arias-Montaño, JA; Bristow, DR; Young, JM | 1 |
| Cale, AD; Demian, I; Gero, TW; Jaques, LW; Jenkins, H; Johnson, AF; Kilpatrick, BF; Nolan, JC; Sleevi, MC; Welstead, WJ | 1 |
| Maeyama, K; Onodera, K; Sakai, N; Watanabe, T; Yanai, K | 1 |
| Fukui, H; Inagaki, N; Ito, S; Kondoh, H; Kubo, A; Wada, H; Yamatodani, A | 1 |
| Advenier, C; Candenas, ML; De Vos, C; Naline, E | 1 |
| Nowak, JZ; Sek, B | 1 |
| Tayo, F | 1 |
| Ahmad, Z; Baumann, G; Blömer, H; Felix, SB; Hashemi, T; Niemczyk, M; Ochsenfeld, G; Shirani, S | 1 |
| Fraser, DG; Regal, JF | 1 |
| Andrews, PV; Boyd, RL; Eglezos, A; Helme, RD | 1 |
| Bogdanovic, RP; Brandes, LJ; Sukhu, B | 1 |
| Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M | 1 |
| Holtzman, MJ; Jacobs, SC; Mahoney, M; Pentland, AP | 1 |
| Ishikawa, T; Sato, M; Shiosaka, S; Tani, E; Tohyama, M | 1 |
| Blanco, I; Rodriguez, J; Rodriguez, R; Sabriá, J; Toledo, A | 1 |
| Di Bello, MG; Gambassi, F; Mannaioni, PF; Masini, E; Pistelli, A; Raspanti, S | 1 |
| Bendele, AM; Fleisch, JH; Wong, WS | 1 |
| Edvinsson, L; Jansen, I; Langemark, M; Olesen, J; Ottosson, AL | 1 |
| Ishikawa, E; Matsukura, S; Nakatsuru, K; Ohgo, S | 1 |
| Knight, DA; Phillips, MJ; Stewart, GA; Thompson, PJ | 1 |
| Stehle, J | 1 |
| Benedito, S; Nielsen, PJ; Nyborg, NC; Prieto, D | 1 |
| Ikeda, S; Kawasaki, A; Nambu, F; Okegawa, T; Omawari, N; Sawada, M; Yube, N | 1 |
| Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y | 1 |
| Calignano, A; Diurno, MV; Mazzoni, O; Piscopo, E | 1 |
| Albers, FJ; Caron, MG; Dennis, VW; Lefkowitz, RJ; Middleton, JP; Obeid, LM; Raymond, JR | 1 |
| Fukui, H; Inagaki, N; Ito, S; Wada, H; Yamatodani, A | 1 |
| Accomazzo, MR; Belloni, P; Crivellari, MT; Melli, M; Mezzetti, M; Oliva, D; Rovati, GE; Torre, M; Verga, A; Viganò, T | 1 |
| Bugajski, J; Chłap, Z; Fogel, WA; Gadek-Michalska, A; Turoń, M | 1 |
| Andersson, RG; Granérus, G; Grundström, N; Lindström, EG | 1 |
| Cooke, HJ; Fertel, R; Su, HC; Wang, YZ | 1 |
| Bökesoy, TA; Onaran, HO | 1 |
| Ballabeni, V; Barocelli, E; Impicciatore, M; Lavezzo, A; Morini, G | 1 |
| Dolata, J; Lindberg, S; Mercke, U | 1 |
| Akiyama, Y; Kamei, C; Mukai, T; Tasaka, K | 1 |
| Heim, HK; Oestmann, A; Sewing, KF | 1 |
| Barthó, L; Kápolnai, L; Petöcz, L; Porszász, J; Porszász, KG; Szolscányi, J; Varga, F | 1 |
| Akins, VF; Bealer, SL | 1 |
| Fernandes, LB; Goldie, RG | 1 |
| Alvarez, EO; Horno, NM | 1 |
| Hill, SJ; Iredale, PA; Kendall, DA; Martin, KF; Ruck, A | 1 |
| Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
| Fukui, H; Inagaki, N; Kanamura, A; Kondou, H; Koyama, Y; Wada, H | 1 |
| Bristow, DR; Young, JM | 1 |
| Bugajski, J; Turon, M; Tyton, J | 1 |
| Cervós-Navarro, J; Sharma, HS | 1 |
| Cruz, MA; González, C; Rudolph, MI; Sepúlveda, WH | 1 |
| Horio, S; Ishida, Y; Nakamura, S | 1 |
| Northover, AM | 1 |
| Hayashi, H; Watanabe, A | 1 |
| Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F | 1 |
| Cooke, HJ; Wang, YZ | 1 |
| Guidobono, F; Netti, C; Pagani, F; Pecile, A; Sibilia, V; Villa, I | 1 |
| Młynarska, MS | 1 |
| Accomazzo, MR; Crivellari, MT; Folco, G; Mezzetti, M; Nicosia, S; Oliva, D; Verga, A; Vigano', T | 1 |
| Matsuki, T; Ohhashi, T | 1 |
| Brown, LA; Chen, M | 1 |
| Barnes, PJ; Ichinose, M | 1 |
| Edvinsson, L; Hill, SJ; Ottosson, A | 1 |
| Hide, M; Nakamura, K; Noso, N; Yamamoto, S | 1 |
| Carswell, H; Crawford, ML; Young, JM | 1 |
| Keitoku, M; Maruyama, Y; Takishima, T | 1 |
| Cluzel, M; Goldman, DW; Lichtenstein, LM; Liu, MC; Undem, BJ | 1 |
| Montaño, LM; Segura, P; Selman, M; Vanda, B; Vargas, MH | 1 |
| Ahluwalia, M; Bazan, E; Garver, D; Gruenstein, E; Johnson, CG; Johnson, CL | 1 |
| Cheung, LY; Wicina, GM; Wood, JG | 1 |
| Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE | 1 |
| Hayashi, M; Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
| Khateb, A; Mühlethaler, M; Serafin, M | 1 |
| Caughey, GH; Graf, PD; Nadel, JA; Rubinstein, I | 1 |
| Johnson, CG; Johnson, CL | 1 |
| Barnes, PJ; Liu, SF; Yacoub, M | 1 |
| Konno, S; Tsurufuji, S | 1 |
| Fjellner, B; Hägermark, O | 1 |
| Harden, TK; Hepler, JR; Hughes, AR; Martin, MW; Nakahata, N | 1 |
| Ledgard, SE; Owen, DA; Pipkin, MA; Woodward, DF | 1 |
| Feniuk, W; Humphrey, PP; Trevethick, MA | 1 |
| Abdullah, NA; Assem, ES | 2 |
| Arrang, JM; Garbarg, M; Schwartz, JC | 1 |
| Hayter, A; Makinde, V; McAteer, E; Suer, AH; Tugwell, AC; Wali, FA | 1 |
| Bakich, V; Brown, JC; Kwok, YN; McIntosh, CH; Wong, J | 1 |
| Drazen, JM; Shore, SA | 1 |
| Andrews, PV; Helme, RD; Khalil, Z; Thomas, KL | 1 |
| Clough, GF; Noor, NM; Smaje, LH | 1 |
| Katusić, ZS; Krstić, MK; Krstić, SK; Stepanović, RM | 1 |
| Ache, BW; McClintock, TS | 1 |
| Friedberg, KD; Sekardi, L | 1 |
| Hishinuma, S; Uchida, MK | 1 |
| Edvinsson, L; Jansen, I; Ottosson, A | 1 |
| Gupta, GP; Tangri, KK; Vrat, S | 1 |
| Guo, ZG; Luo, WS | 1 |
| Bugajski, J; Gadek-Michalska, A | 1 |
| Björck, T; Dahlén, SE | 1 |
| Hallam, TJ; Jacob, R; Merritt, JE | 1 |
| Khan, MA; Sen, PC | 1 |
| Fujimoto, K; Fukagawa, K; Ookuma, K; Sakata, T; Shiraishi, T; Wada, H; Yoshimatsu, H | 1 |
| Chung, YH; Mio, M; Sawada, K; Tasaka, K | 1 |
| Chahl, LA; Fyfe, MC | 1 |
| Akamine, M; Kitazawa, T; Kondo, H; Ohta, T; Shimizu, T; Temma, K | 1 |
| Itoh, Y; Nishibori, M; Oishi, R; Saeki, K | 2 |
| Ezeamuzie, CI; Umezurike, CC | 1 |
| Garbarg, M; Gros, C; Schwartz, JC; Tuong, MD | 1 |
| Dailey, RA; Hall, JA; Lewis, PE; Meisterling, EM | 1 |
| Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM | 1 |
| Itowi, N; Matsumura, K; Nakayama, T; Tsai, CL; Wada, H; Yamatodani, A | 1 |
| Hazama, A; Okada, Y; Yada, T | 1 |
| Gupta, S; Katiyar, JC; Patnaik, GK; Srimal, RC | 1 |
| Bhandari, P; Bhargava, KP; Chugh, A; Dixit, KS; Gupta, YK; Seth, SD | 1 |
| Bennett, TE; Driver, AG; Kukoly, CA | 1 |
| Chansouria, JP; Dey, PK; Mohanty, S; Olsson, Y; Sharma, HS; Singh, S | 1 |
| Gary, RK; Gleason, JG; Nieves, AL; Wasserman, MA; Williams, LS; Woodward, DF | 1 |
| Kanaide, H; Kobayashi, S; Kuga, T; Matsumoto, T; Nakamura, M; Nishimura, J | 1 |
| Bunn, SJ; Livett, BG; Wan, DC | 1 |
| Acevedo, CG; Cruz, MA; Gonzalez, C; Rudolph, MI; Sepulveda, WH | 1 |
| Chen, G; Suzuki, H | 1 |
| Adaikan, PG; Lau, LC; Ratnam, SS | 1 |
| Jorgenson, KL; Kow, LM; Pfaff, DW | 1 |
| Taylor, DJ; Woolley, DE | 2 |
| Ono, H; Suzuki, H | 1 |
| Claro, E; García, A; Picatoste, F | 1 |
| Trzeciakowski, JP | 2 |
| Imoto, M; Koyama, Y; Nimura, Y; Nishikimi, M; Ozawa, T; Shionoya, S; Tanaka, M; Tsuchie, K | 1 |
| Boarder, MR; Plevin, R | 1 |
| Girard, A; Marche, P | 1 |
| Boarder, MR; Marriott, DB; Plevin, R | 1 |
| Braquet, P; Cabanie, M; Chabrier, PE; Demerle, C; Esanu, A; Girard, A; Lonchampt, MO; Marche, P | 1 |
| Imoto, M; Ozawa, T; Sugiyama, S; Tanaka, M; Tsuchie, K | 1 |
| Heldsinger, AA; Pittenger, GL; Seino, S; Vinik, AI | 1 |
| Kondo, M; Tanaka, C; Taniyama, K | 1 |
| Ozer, A; Tuğrul, L | 1 |
| Foreman, JC; Norris, DB; Rising, TJ; Webber, SE | 1 |
| Katona, PG; Rigel, DF | 1 |
| Livingston, A; Nolan, A; Waterman, A | 1 |
| Malo, PE; Muccitelli, R; Tucker, SS; Wasserman, MA | 1 |
| Hawley, SB; Nieves, AL; Spada, CS; Woodward, DF | 1 |
| Hutchison, VH; Spriestersbach, KK | 1 |
| Knigge, U; Matzen, S; Warberg, J | 2 |
| Brown, EA; Griffiths, R; Harvey, CA; Owen, DA | 1 |
| Genovese, A; Levi, R | 1 |
| Hirasawa, N; Ohuchi, K; Tsurufuji, S; Watanabe, M | 2 |
| Cordeiro, RS; Corrêa, FM; Henriques, MG; Martins, MA; Silva, PM | 1 |
| Alvarez, EO; Banzan, AM | 4 |
| Fu, SX; Li, CG; Li, YS | 1 |
| Miyazaki, H; Ohga, A; Taneike, T | 1 |
| Arbonés, L; García, A; Picatoste, F | 1 |
| Clerici, C; Franco-Montoya, ML; Harf, A; Macquin-Mavier, I | 1 |
| Krstić, MK | 1 |
| Männistö, PT; Mattila, J; Tuominen, RK | 2 |
| Akahori, H; Kamei, C; Kitazumi, K; Tasaka, K | 1 |
| Ledgard, SE; Nieves, AL; Woodward, DF | 1 |
| Barker, LA; Winbery, SL | 1 |
| Donaldson, J; Hill, SJ | 3 |
| Kim, LE; Oudart, N; Sercombe, R; Teste, JF | 1 |
| Chaya, M; De Heng, S; Hirooka, Y; Mitsuma, T; Nogimori, T; Ohtake, K | 1 |
| Baltes, E; De Vos, C; Gobert, J; Maleux, MR | 1 |
| Iwata, M; Kohno, S; Shigei, T; Tsuru, H | 1 |
| Abacioğlu, N; Demiryürek, T; Ercan, ZS; Kanzik, L; Türker, RK; Zengil, H | 1 |
| Jouvet, M; Lin, JS; Sakai, K | 2 |
| Dhawan, KN; Gulati, A; Gupta, GP; Nath, C | 1 |
| Ea-Kim, L; Oudart, N | 1 |
| Daly, JW; Hollingsworth, EB | 1 |
| Donoso, AO; Podestá, E; Seltzer, AM | 1 |
| Aikawa, T; Hirose, T; Matsumoto, I; Morikawa, T; Tsujimoto, Y | 1 |
| Arbonés, L; Claro, E; García, A; Picatoste, F | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Fromm, D; Furukawa, T; Olender, EJ; Woods, DJ | 1 |
| Hirose, K; Hori, Y; Jyoyama, H; Katori, M; Takagi, M; Yamada, K | 1 |
| Chaya, M; Mitsuma, T; Nogimori, T; Sun, DH | 1 |
| Evans, DC; Lin, TM; Ruffolo, RR; Warrick, MW | 1 |
| Fujiki, H; Hayashi, Y; Hirasawa, N; Ohuchi, K; Sugimura, T; Takahashi, C; Tsurufuji, S; Watanabe, M | 1 |
| Hirooka, Y; Mitsuma, T; Nogimori, T | 1 |
| Conder, GA; Elfring, G; Griffin, RL; Oostveen, JA; Richards, IM | 1 |
| Fukuda, H; Ito, Y; Maeyama, K; Wada, H; Watanabe, T | 1 |
| Bohm, U; Falus, A; Fekete, MI; Meretey, K | 1 |
| Allescher, HD; Berezin, I; Daniel, EE; Jury, J | 1 |
| Guo, ZG; Zhou, CJ | 1 |
| Bennett, GW; Bristow, LJ | 1 |
| Itowi, N; Nagai, K; Nakagawa, H; Wada, H; Watanabe, T | 1 |
| Guth, PS; Housley, GD; Norris, CH | 1 |
| Anaya, T; Chenoweth, DE; Chick, TW; Crowell, RE; Leach, J; Reed, WP; Van Epps, D | 1 |
| Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
| Mitsuhashi, M; Payan, DG | 1 |
| Palmer, JM; Tamura, K; Wood, JD | 1 |
| Kristofová, A; Machová, J | 1 |
| Cross, KS; el-Sanadiki, MN; Hagen, PO; McCann, RL; Mikat, EM; Murray, JJ | 1 |
| Mammen, GJ; Pennefather, JN | 1 |
| Campbell, WB; Hughes, MJ; Johnson, AR; Revtyak, GE | 1 |
| Hirst, BH | 1 |
| Xu, YH; Yi, SN | 1 |
| Greenidge, E; Hayter, A; Makinde, V; Wali, FA | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Dveksler, G; Franchi, AM; Gimeno, AL; Gimeno, MF; Viggiano, M | 1 |
| Chen, J; Johnson, L; Spada, C; Woodward, DF | 1 |
| Charap, A; Duzman, E; Leon, J; Shen, CD | 1 |
| Ishii, K; Kato, R | 1 |
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| Galosi, R; Haas, H; Huston, JP; Knoche, A; Lenard, L; Schwarting, RK | 1 |
| Hardwick, JC; Peterson, BA; Powers, MJ | 1 |
| Cheng, JS; Chou, KJ; Jan, CR; Lee, KC; Tang, KY; Tseng, LL; Wang, JL | 1 |
| Kohno, S; Mizutani, N; Nabe, T; Osaki, S; Sugahara, S; Takenaka, H | 1 |
| Inagaki, N; Kanke, T; Matsumoto, J; Nagai, H; Nagao, M; Takizawa, T; Timmerman, H; Tohma, T; Wada, Y; Zhang, MQ | 1 |
| Gitlin, JM; Mitchell, JA; Stanford, SJ | 1 |
| Attoub, S; Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L; Sobhani, I | 1 |
| Masuyama, K; Minoda, R; Toriya, T; Yumoto, E | 1 |
| Bakker, RA; Leurs, R; Schoonus, SB; Smit, MJ; Timmerman, H | 1 |
| Chang, HT; Cheng, JS; Chou, KJ; Jan, CR; Lee, KC; Tang, KY; Wang, JL | 1 |
| Ghosh, AK; Hirasawa, N; Ohuchi, K | 1 |
| Chang, HT; Chen, WC; Chou, KJ; Huang, JK; Jan, CR; Law, YP; Lee, KC; Lo, YK; Su, W; Tang, KY; Wang, JL | 1 |
| Eltorp, CT; Hansen, AJ; Ingvardsen, BK; Jørgensen, TK; Lundbaek, JA; Olsen, UB; Thomsen, C | 1 |
| Funahashi, H; Goto, K; Guan, JL; Honda, K; Sakurai, T; Shioda, S; Tominaga, M; Tsujino, N; Wang, QP; Yamanaka, A | 1 |
| Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE | 1 |
| Aigueperse, J; Francois, A; Griffiths, NM; Ksas, B | 1 |
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| Chen, Z; Li, WD; Shen, YJ; Wei, EQ; Zhu, LJ | 1 |
| Fang, YI; Hashimoto, T; Momose, K; Nakano, Y; Ohata, H; Yamashita, M | 1 |
| Benfeldt, E; Jensen, SB; Menné, T; Serup, J; Thomsen, JS | 1 |
| Chiba, Y; Matsuo, K; Misawa, M; Saitoh, N | 1 |
| Arias-Montaño, JA; García, L; Guerrero-Hernández, A; Rueda, A; Soria-Jasso, LE | 1 |
| Adachi, T; Hori, Y; Ishigaki-Suzuki, S; Kagaya, Y; Kikuchi, Y; Makabe-Kobayashi, Y; Nagy, A; Ohtsu, H; Shirato, K; Takai, T; Ujike, A; Watanabe, T | 1 |
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| Bacon, KB; Center, DM; Cruikshank, WW; Gantner, F; Sakai, K; Tusche, MW | 1 |
| Endo, Y; Fujita, T; Matsushita, M; Ohtaki, Y; Takada, H; Yamaguchi, K; Yokochi, T; Zhao, L | 1 |
| Aceves, J; Arias-Montaño, JA; Bárbara, A | 1 |
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| Akerman, S; Goadsby, PJ; Kaube, H; Williamson, DJ | 1 |
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| Burckstummer, T; Buschauer, A; Dove, S; Elz, S; Pertz, HH; Schunack, W; Seifert, R; Wenzel-Seifert, K | 1 |
| Bischoff, AM; Büsselberg, D; Dutschmann, M; Richter, DW | 1 |
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| Jain, V; McWilliams, E; Young, M | 1 |
| Assadi, E; Oryan, S; Sahebgharani, M; Torkaman-Boutorabi, A; Zarrindast, MR | 1 |
| Nakamura, T; Ueno, K; Yamaura, K; Yano, S; Yonekawa, T | 1 |
| Chen, Z; Hu, WW; Huang, YW; Wei, EQ; Yanai, K; Zhang, LS | 1 |
| Gao Zhang, C; Kim, SJ; Taek Lim, J | 1 |
| Dahlén, SE; Låstbom, L; Ryrfeldt, A; Sundström, E | 1 |
| Jørgensen, H; Kjaer, A; Knigge, U; Kristoffersen, U; Madsen, K; Toftegaard, C; Warberg, J | 1 |
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| NORTHOVER, BJ; SUBRAMANIAN, G | 1 |
| HALPERN, BN; NEVEU, T; SPECTOR, S | 1 |
| RANG, HP | 1 |
| PATON, WD; ROTHSCHILD, AM | 1 |
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| Bernsand, M; Bjorkqvist, M; Ericsson, P; Hakanson, R; Norlen, P; Zhao, CM | 1 |
| Clifton, PG; Hartfield, AW; Moore, NA | 1 |
| Jeong, JH; Lee, TS; Shin, CY; Sohn, UD; Song, HJ; Yun, MC | 1 |
| SZAMA, HE; VIGLIOGLIA, PA | 1 |
| KOSKOWSKI, W; MAHFOUZ, M | 1 |
| Bakker, RA; Bruysters, M; Chatelain, P; Gillard, M; Leurs, R; Pertz, HH; Schunack, W; Teunissen, A; Timmerman, H | 1 |
| Alvarez, EO; Ruarte, MB | 1 |
| Aikawa, T; Inoue, Y; Matsumoto, I; Shimada, T; Tsuchiya, K | 1 |
| Bon, C; Cruz-Höfling, MA; Ferreira de Araújo, PM; Guimarães, AQ; Lôbo de Araújo, A | 1 |
| MILLER, AA; PEDLEY, E | 1 |
| Coppé, MC; Gillardin, JM; Girard, P; Pansart, Y; Verniers, D | 1 |
| Fukui, H; Horio, S; Kawakami, N; Miyoshi, K | 1 |
| Brzozowski, T; Ceranowicz, P; Dembiński, A; Dembiński, M; Konturek, SJ; Pawlik, WW; Warzecha, Z | 1 |
| Khan, MM; Patterson, EB; Sakhalkar, SP | 1 |
| Haas, HL; Korotkova, TM; Ponomarenko, AA; Sergeeva, OA | 1 |
| Lai, YL; Lin, CH | 1 |
| Campbell, VC; Katz, JL; Kopajtic, TA; Newman, AH | 1 |
| Farahmanfar, M; Fazli-Tabaei, S; Khalilzadeh, A; Yahyavi, SH; Zarrindast, MR | 1 |
| Djahanguiri, B; Khalilzadeh, A; Zarrindast, MR | 1 |
| Ishii, K; Maruko, T; Nakahara, T; Saito, M; Sakamoto, K; Sugimoto, N; Takuwa, Y | 1 |
| Roohbakhsh, A; Rostami, P; Zarei, M; Zarrindast, MR | 1 |
| Moghadam, AH; Roohbakhsh, A; Rostami, P; Zarrindast, MR | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Martínez, AC; Pagán, RM; Prieto, D; Raposo, R | 1 |
| Chen, Z; Hu, WW; Liu, LY; Ma, L; Wei, EQ; Xu, LS; Yang, LX; Yu, X | 1 |
| Eckman, JR; Wagner, MC; Wick, TM | 1 |
| Holopainen, IE; Kukko-Lukjanov, TK; Michelsen, KA; Panula, P; Soini, S; Taira, T | 1 |
| Gálfi, M; Juhász, A; László, F; László, FA; Molnár, A; Radács, M; Varga, C | 1 |
| Hajizadeh-Moghaddam, A; Rostami, P; Zarrindast, MR | 1 |
| Carlos, D; de Paula, L; Faccioli, LH; Jamur, MC; Martins, MA; Matias-Peres, C; Oliver, C; Sá-Nunes, A; Serra, MF | 1 |
| Dube, PH; Handley, SA; Miller, VL | 1 |
| Moghimi, M; Rezayof, A; Rostami, P; Zarrindast, MR | 1 |
| Chang, LW; Chen, SC; Tsai, MH; Wang, HJ; Yu, HS | 1 |
| Fazli-Tabaei, S; Rostami, P; Torabi, M; Zarrindast, MR | 1 |
| Adachi, Y; Fujii, Y; Kamei, C; Yamamoto, Y | 1 |
| Higuchi, H; Nagai, S; Niki, T; Piao, H; Tsurumaki, T | 1 |
| Dutschmann, M; Gratzl, M; Lazarov, N; Reindl, S; Rey-Ares, V; Rozloznik, M | 1 |
| Green, C; Hewlett, E; Hughes, M; Padgett, D; Schwartz, L; Tessier, J; Zhao, W | 1 |
| Das, AK; Dev, S; Fujimoto, K; Fukui, H; Horio, S; Kitamura, Y; Mishima, R; Mizuguchi, H; Takeda, N; Wakayama, Y; Yoshimura, S | 1 |
| Kamei, C; Masuoka, T | 1 |
| Khan, UW; Rai, U | 1 |
| Seifert, R; Strasser, A; Striegl, B; Wittmann, HJ | 1 |
| BAIN, WA; BROADBENT, JL; WARIN, RP | 1 |
| ANDERSON, LT; GAKENHEIMER, WC | 1 |
| Fukino, K; Ikawa, Y; Kuribayashi, M; Ohkuni, Y; Ueno, K; Yonekawa, T | 1 |
| Bennedich Kahn, L; Gustafsson, LE; Olgart Höglund, C | 1 |
| Rezayof, A; Rostami, P; Valizadegan, F; Zarrindast, MR | 1 |
| Decaluwé, K; Nimmegeers, S; Van de Voorde, J | 1 |
| Ales, K; Lipnik-Stangelj, M; Wraber, B | 1 |
| Liang, H; Liu, B; Liu, L; Zhang, H | 1 |
| Hajizadeh Moghaddam, A; Heidary-Davishani, A; Roohbakhsh, A; Rostami, P; Zarrindast, MR | 1 |
| Qi, Y; Qian, ZB; Wu, ZH | 1 |
| Alcayaga, J; Del Rio, R; Fujiwara, K; Iturriaga, R; Koenig, CS; Moya, EA | 1 |
| HERXHEIMER, H | 1 |
| Hirasawa, N; Hong, J; Ishihara, K; Katoh, G; Ohsawa, Y; Ohuchi, K; Seyama, T; Shibata, K; Tamura, S | 1 |
| Chen, Z; Fan, YY; He, P; Hu, WW; Xu, LS; Zhang, WP | 1 |
| Das, AK; Dev, S; Fukui, H; Hattori, M; Horinaga, S; Kato, S; Maeyama, K; Mizuguchi, H; Tamada, M; Umehara, H | 1 |
| Arias, K; Baig, M; Chu, D; Colangelo, M; Coyle, A; Goncharova, S; Jordana, M; Vadas, P; Walker, T; Waserman, S | 1 |
| Alcayaga, J; Iturriaga, R; Moya, EA; Rio, RD | 1 |
| Hau, CS; Ishikawa, T; Kanda, N; Tada, Y; Watanabe, S | 1 |
| Bina, P; Nasehi, M; Piri, M; Zarrindast, MR | 1 |
| Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E | 2 |
| Maslinski, S; Mittal, TK; Rongies, W; Szewczyk, G; Szukiewicz, D | 1 |
| Katzoff, A; Miller, N; Susswein, AJ | 1 |
| Khodarahmi, P; Oryan, S; Rezayof, A; Zarrindast, MR | 1 |
| Ahmadi, S; Malekmohammadi, N; Zarrindast, MR | 1 |
| Caldas Magalhães, PJ; Lahlou, S; Leal-Cardoso, JH; Weinreich, D | 1 |
| Cauley, M; Cousins, V; Hampton, D; Levin, ED; Petro, A; Pruitt, M; Rose, J; Slade, S; Wells, C | 1 |
| Arrang, JM; Burban, A; Davenas, E; Motawaj, M | 1 |
| Borrebaeck, CA; Broos, S; Greiff, L; Lindstedt, M; Lundberg, K | 1 |
| Dileepan, KN; Levant, B; Raveendran, VV; Slusser, J; Stechschulte, DJ; Sweeney, ME; Tan, X | 1 |
| Hirasawa, N; Ohuchi, K | 1 |
| Ghasri, S; Hamzely, A; Khoshkholgh Sima, B; Mobarakeh, JI; Nezhad, RM; Nunoki, K; Rahimi, AA; Takahashi, K; Torkaman-Boutorabi, A; Yanai, K | 1 |
| Seifert, R; Strasser, A; Wittmann, HJ | 1 |
| Browning, C; Clark, KL; Connor, HE; Ford, AJ; Hall, DA; Hodgson, ST; Luttmann, MA; Russell, LJ; Saunders, KA; Slack, RJ | 1 |
| Tseng, CL; Wei, JW | 2 |
| Asgariyan, M; Nasehi, M; Piri, M; Zarrindast, MR | 1 |
| Tabarean, IV | 1 |
| Ali, AS; Ali, SA; Salim, S | 1 |
| Jimenez-Gomez, C; Podlesnik, CA | 1 |
| Charest-Morin, X; Gera, L; Marceau, F; Roy, C | 1 |
| Perdomo, G; Riveros, ME; Torrealba, F | 1 |
| Miranda, MI; Purón-Sierra, L | 1 |
| Alagar Yadav, S; Jabamalai Raj, A; Ramalingam, S; Subban, R | 1 |
| Colwell, CS; Han, HC; Kim, WB; Kim, YB; Kim, YI; Kim, YS; Lee, CJ; Lee, SW; Shen, FY; Soong, TW; Yoon, BE | 1 |
| Chen, J; Deng, L; Ding, S; Ge, J; Hong, T; Huang, Z; Jia, J; Lin, J; Wang, TC; Yang, X; Zou, Y | 1 |
| de Oliveira Borges, M; Fischer, L; Lavoranti, MI; Martynhak, BJ; Miksza, AF; Parada, CA; Sardi, NF; Tambeli, CH | 1 |
| Lkhagvasuren, B; Oka, T | 1 |
| Ebenezer, AJ; Prasad, K; Rajan, S; Thangam, EB | 1 |
| Chess-Williams, R; Moro, C; Stromberga, Z | 1 |
| Egger, KN; Javed, S; Lee, CH; Massicotte, HB; Mitchell, K; Payne, GW; Reutens-Hernandez, J; Sellers, SL; Sidsworth, D | 1 |
| Aneesha, VA; Gopi, RP; Kumar, D; Kumawat, S; Susanth, VS; Vineetha, S | 1 |
| Hale, MW; Lesku, JA; Omond, SET | 1 |
4 review(s) available for pyrilamine and histamine
| Article | Year |
|---|---|
Histamine H3 ligands: just pharmacological tools or potential therapeutic agents?
Topics: Animals; Histamine; Histamine Antagonists; Molecular Structure; Neurotransmitter Agents; Receptors, Histamine; Receptors, Histamine H3; Structure-Activity Relationship | 1990 |
Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum.
Topics: Alkaloids; Analgesics; Animals; Burimamide; Cardiovascular System; Chemical Phenomena; Chemistry; Connective Tissue; Dogs; Haplorhini; Histamine; Histamine Release; Humans; Japan; Methyl Ethers; Mice; Morphinans; Plants, Medicinal; Pyrilamine; Rabbits; Rats; Rheumatic Diseases | 1976 |
Histamine as a transmitter in brain.
Topics: Age Factors; Amino Acids; Animals; Brain; Carboxy-Lyases; Cyclic AMP; Histamine; Histidine Decarboxylase; Humans; Mast Cells; Metiamide; Neural Pathways; Neurons; Neurotransmitter Agents; Pyrilamine; Receptors, Drug; Synaptic Transmission | 1975 |
[Roles of histamine in the exacerbated allergic dermatitis].
Topics: Animals; Cyclosporine; Dermatitis, Atopic; Disease Models, Animal; Drug Therapy, Combination; Histamine; Histamine Antagonists; Humans; Mice; Picryl Chloride; Piperidines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3; Receptors, Histamine H4; Tetradecanoylphorbol Acetate | 2011 |
9 trial(s) available for pyrilamine and histamine
| Article | Year |
|---|---|
Human gastric mucosal adenylate cyclase: activation by histamine-H2-receptor stimulation and inhibition by cimetidine in vitro and in peptic ulcer patients.
Topics: Adenylyl Cyclases; Cimetidine; Clinical Trials as Topic; Enzyme Activation; Female; Gastric Mucosa; Guanidines; Histamine; Humans; Male; Middle Aged; Peptic Ulcer; Phenethylamines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Thiourea | 1979 |
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A | 1991 |
Experimental pruritus evoked by platelet activating factor (PAF-acether) in human skin.
Topics: Adult; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Female; Histamine; Humans; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pruritus; Pyrilamine; Skin | 1985 |
Efficacy of cimetidine/pyrilamine eyedrops. A dose response study with histamine challenge.
Topics: Adult; Aminopyridines; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Eye; Eye Diseases; Female; Histamine; Humans; Hyperemia; Hypersensitivity; Male; Ophthalmic Solutions; Pyrilamine | 1986 |
The effect of histamine on the human fingertip circulation.
Topics: Cimetidine; Cold Temperature; Fingers; Histamine; Humans; Norepinephrine; Pyrilamine; Regional Blood Flow; Vascular Resistance; Vasoconstriction | 1984 |
Headache provocation by continuous intravenous infusion of histamine. Clinical results and receptor mechanisms.
Topics: Aminopyridines; Cimetidine; Headache; Histamine; Humans; Migraine Disorders; Pyrilamine | 1980 |
Histamine induces migraine via the H1-receptor. Support for the NO hypothesis of migraine.
Topics: Adolescent; Adult; Double-Blind Method; Female; Hemodynamics; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Migraine Disorders; Nitric Oxide; Pyrilamine; Receptors, Histamine H1; Time Factors | 1995 |
Effects of two antihistamines on chloroquine and histamine induced weal and flare in healthy African volunteers.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Black People; Chloroquine; Clemastine; Cross-Over Studies; Histamine; Humans; Injections, Intradermal; Male; Pruritus; Pyrilamine; Single-Blind Method | 1994 |
Topically applied aspirin decreases histamine-induced wheal and flare reactions in normal and SLS-inflamed skin, but does not decrease itch. A randomized, double-blind and placebo-controlled human study.
Topics: Administration, Topical; Adult; Analysis of Variance; Aspirin; Dermatitis, Irritant; Double-Blind Method; Female; Histamine; Humans; Injections, Intradermal; Male; Pain; Probability; Prospective Studies; Pruritus; Pyrilamine; Reference Values; Sensitivity and Specificity; Severity of Illness Index; Skin Tests; Sodium Dodecyl Sulfate; Treatment Outcome | 2002 |
850 other study(ies) available for pyrilamine and histamine
| Article | Year |
|---|---|
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium | 2001 |
A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; DNA, Complementary; Guinea Pigs; Histamine; Histamine Agonists; Humans; Ileum; Inositol Phosphates; Ligands; NF-kappa B; Pyrilamine; Radiopharmaceuticals; Receptors, Histamine H1; Tetrahydronaphthalenes; Thermodynamics; Transfection; Type C Phospholipases | 2002 |
Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.
Topics: Animals; Binding, Competitive; Cell Line; Chlorocebus aethiops; Genes, Reporter; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Inositol Phosphates; Ligands; NF-kappa B; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Structure-Activity Relationship | 2003 |
Large-scale overproduction, functional purification and ligand affinities of the His-tagged human histamine H1 receptor.
Topics: Animals; COS Cells; Histidine; Humans; Ligands; Radioligand Assay; Receptors, Histamine H1; Spodoptera | 2004 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Linking agonist binding to histamine H1 receptor activation.
Topics: Animals; Chlorocebus aethiops; COS Cells; Histamine Agonists; Humans; Models, Molecular; Mutation; Protein Structure, Tertiary; Receptors, Histamine H1; Serine | 2005 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The selective eosinophil chemotactic activity of histamine.
Topics: Amine Oxidase (Copper-Containing); Chemotaxis; Dose-Response Relationship, Drug; Eosinophils; Histamine; Histamine H1 Antagonists; Histidine; Humans; Metiamide; Pyrilamine | 1975 |
Histamine receptors in the vasculature of the rabbit ear.
Topics: Acetylcholine; Angiotensin II; Animals; Arteries; Ear; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Metiamide; Muscle Contraction; Norepinephrine; Pyrilamine; Rabbits; Receptors, Drug; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1975 |
Action of H1 and H2 inhibitors on the response of histamine sensitive adenyly cyclase from guinea-pig mucosa.
Topics: Adenylyl Cyclases; Animals; Burimamide; Female; Gastric Mucosa; Guinea Pigs; Histamine; Histamine H1 Antagonists; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Receptors, Drug | 1976 |
Proceedings: Inhibition by antigen and by histamine antagonists of the uptake of histamine by isolated human leucocytes.
Topics: Antigens; Depression, Chemical; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Leukocytes; Metiamide; Pyrilamine; Tuberculin | 1976 |
Histamine H2-receptors in the human peripheral circulation.
Topics: Forearm; Histamine; Histamine H1 Antagonists; Humans; Metiamide; Pyrilamine; Receptors, Drug; Regional Blood Flow; Time Factors; Vasodilator Agents | 1976 |
Identification and blockade of vascular H2 receptors.
Topics: Animals; Dogs; Female; Hindlimb; Histamine; Histamine H1 Antagonists; Male; Metiamide; Muscles; p-Methoxy-N-methylphenethylamine; Pyrilamine; Receptors, Drug; Stomach; Vascular Resistance | 1976 |
Blocking of olive oil induced plasma protein escape from the intestinal circulation by histamine antagonists and by a diamine oxidase releasing agent.
Topics: Amine Oxidase (Copper-Containing); Animals; Blood Proteins; Burimamide; Female; Heparin; Histamine; Histamine H1 Antagonists; Intestinal Mucosa; Intestines; Lymph; Oils; Pyrilamine; Rats; Regional Blood Flow | 1976 |
Inhibition of adjuvant arthritis by histamine.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Body Weight; Burimamide; Histamine; Histamine H1 Antagonists; Male; Pyrilamine; Rats; Time Factors | 1976 |
Effects of changes in pH of bath fluid on isolated guinea pig ileum preparation.
Topics: Acetylcholine; Animals; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Antagonists; Hydrogen-Ion Concentration; Ileum; Muscle Contraction; Pyrilamine | 1976 |
Histamine2--receptor blockade with cimetidine in the monkey cranial circulation.
Topics: Animals; Blood Pressure; Carotid Arteries; Carotid Artery, External; Carotid Artery, Internal; Cerebrovascular Circulation; Depression, Chemical; Dose-Response Relationship, Drug; Guanidines; Haplorhini; Histamine; Histamine H2 Antagonists; Imidazoles; Macaca; Pyrilamine; Vascular Resistance | 1976 |
Atypical (relaxant) response to histamine in cat bronchus.
Topics: Airway Resistance; Animals; Bronchi; Burimamide; Carbachol; Cats; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Male; Metiamide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Propranolol; Pyrilamine; Trachea | 1977 |
Dualist or pseudo-dualist interactions of mepyramine, diphenhydramine and eprozinol with histamine at H1-receptors.
Topics: Animals; Binding, Competitive; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Piperazines; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Trachea | 1977 |
Chemotactic activity of guinea pig eosinophils for the ECF-A acidic tetrapeptides, histamine, histamine metabolites, and the effect of H1- and H2-receptor antagonists.
Topics: Alanine; Anaphylaxis; Animals; Burimamide; Chemotaxis, Leukocyte; Dose-Response Relationship, Immunologic; Eosinophils; Female; Glutamates; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Imidazoles; Male; Methylhistamines; Oligopeptides; Pyrilamine; Valine | 1977 |
Investigation of the role of histamine H1-receptors in the control of gastric acid secretion in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Ethylamines; Female; Gastric Juice; Histamine; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1978 |
Pharmacological studies on the pulmonary vein of the horse. I. Effects of selected spasmogens.
Topics: Animals; Autacoids; Bradykinin; Carbachol; Histamine; Horses; In Vitro Techniques; Methysergide; Metiamide; Phenylephrine; Pulmonary Veins; Pyrilamine; Serotonin; Vasoconstriction | 1978 |
Effects of histamine on contractility and conduction in isolated chicken hearts.
Topics: Animals; Cardiac Pacing, Artificial; Chickens; Heart Conduction System; Heart Rate; Histamine; Histamine Antagonists; Male; Myocardial Contraction; Pyrilamine; Receptors, Histamine H1 | 1978 |
The dilating effect of histamine on pial arteries of cats and its mediation by H2 receptors.
Topics: Animals; Arteries; Cats; Cimetidine; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Pia Mater; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2 | 1979 |
Local control of blood flow in the dog's stomach: vasodilatation caused by acid back-diffusion following topical application of salicylic acid.
Topics: Animals; Atropine; Capillary Permeability; Cimetidine; Diffusion; Dogs; Histamine; Hydrochloric Acid; Hydrogen-Ion Concentration; Papaverine; Perfusion; Pyrilamine; Salicylates; Stomach; Vasodilation | 1979 |
A pharmacological analysis of the contractile action of histamine upon the ileal region of the isolated, blood-perfused small intestine of the rat.
Topics: Animals; Drug Interactions; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Injections, Intra-Arterial; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rats; Serotonin | 1979 |
Histamine H1- and H2- receptor antagonists reduce histamine-induced increases in vascular permeability and oedema formation in cat skeletal muscle.
Topics: Animals; Bradykinin; Capillary Permeability; Cats; Edema; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Metiamide; Muscles; Pyrilamine; Regional Blood Flow; Serum Albumin; Vasodilation | 1979 |
Inhibition of granulation tissue growth by histamine.
Topics: Amine Oxidase (Copper-Containing); Animals; Burimamide; Depression, Chemical; Granulation Tissue; Growth; Guanidines; Histamine; Histamine Release; Male; Methyl Ethers; Morphinans; Phenylbutazone; Prednisolone; Pyrilamine; Rats | 1975 |
Studies in experimental eosinophilia. XI. Dependence of eosinophilia, apparently induced by histamine, on acidity.
Topics: Amino Acids; Animals; Bone Marrow Cells; Eosinophilia; Female; gamma-Globulins; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Lymph Nodes; Puromycin; Pyrilamine | 1976 |
Histamine H2 receptor: involvement in gastric ulceration.
Topics: Animals; Aspirin; Corticosterone; Female; Histamine; Histamine H1 Antagonists; Histamine Release; Metiamide; Pyrilamine; Rats; Receptors, Drug; Stomach Ulcer; Stress, Physiological | 1976 |
Histamine enhances anaphylactic histamine release from bovine lung and leukocytes via histamine H2-receptor.
Topics: Anaphylaxis; Animals; Cattle; Granulocytes; Histamine; Histamine Release; In Vitro Techniques; Leukocytes; Lung; Male; Metiamide; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2 | 1978 |
Is histamine a mediator in bile-induced gastric mucosal injury?
Topics: Animals; Bile; Cimetidine; Disease Models, Animal; Dogs; Gastric Mucosa; Histamine; Histamine Release; Humans; Hydrogen-Ion Concentration; Membrane Potentials; Permeability; Pyrilamine; Sodium; Stomach Diseases; Taurocholic Acid | 1978 |
Human lung tissue and anaphylaxis: the effects of histamine on the immunologic release of mediators.
Topics: Antigens; Biological Assay; Cimetidine; Cyclic AMP; Cyclic GMP; Diphenhydramine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Lung; Methylhistamines; Metiamide; Pyrilamine; SRS-A | 1978 |
Human lung tissue and anaphylaxis:cyclic nucleotide response and prostaglandin synthesis.
Topics: Anaphylaxis; Cell Communication; Cyclic AMP; Cyclic GMP; Diphenhydramine; Histamine; Histamine Release; Humans; Lung; Prostaglandins; Prostaglandins F; Pyrilamine; Time Factors | 1979 |
Effects of histamine receptor antagonists on histamine-induced responses in human skin.
Topics: Adult; Axons; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Injections, Intradermal; Lidocaine; Metiamide; Pyrilamine; Reflex; Skin | 1979 |
Possible involvement of endogenous histamine in the myotropic effect of clonidine on the isolated rabbit aorta.
Topics: Amine Oxidase (Copper-Containing); Animals; Aorta, Thoracic; Blood Vessels; Clonidine; Female; Histamine; Histidine Decarboxylase; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phentolamine; Pyrilamine; Rabbits | 1978 |
Histaminergic involvement in thyrotropin-releasing hormone stimulation of antral tissue in the rat.
Topics: Animals; Atropine; Bethanechol Compounds; Cimetidine; Histamine; In Vitro Techniques; Male; Muscle Contraction; Pyloric Antrum; Pyrilamine; Rats; Thyrotropin-Releasing Hormone | 1979 |
[Effects of histamine and its derivatives on the excitability of a giant identifiable neuron of Achatina fulica Férussac. A histaminergic receptor different from H1 and H2].
Topics: Action Potentials; Animals; Burimamide; Histamine; Imidazoles; Neurons; Pyrazoles; Pyrilamine; Receptors, Histamine; Snails; Structure-Activity Relationship | 1976 |
The relationship between prostaglandin release and lung c-AMP levels during anaphylaxis in the guinea-pig.
Topics: Anaphylaxis; Animals; Burimamide; Cyclic AMP; Guinea Pigs; Histamine; Immunization; Indomethacin; Isoproterenol; Lung; Ovalbumin; Polyphloretin Phosphate; Propranolol; Prostaglandins E; Prostaglandins F; Pyrilamine; Serotonin | 1975 |
Characterization of an adenylate cyclase system sensitive to histamine H2-receptor excitation in cells from dog gastric mucosa.
Topics: Adenylyl Cyclase Inhibitors; Animals; Burimamide; Cells; Chlorpheniramine; Cyclic AMP; Dogs; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Kinetics; Methylhistamines; Metiamide; Promethazine; Pyrilamine | 1976 |
[Hormonal stimulation of adenosine 3',5'-cyclic monophosphate formation in cell-free particles and intact cells of smooth muscle in the aorta and femoral artery of rats during immubilization stress].
Topics: Adenylyl Cyclases; Animals; Aorta; Blood Pressure; Burimamide; Cyclic AMP; Epinephrine; Femoral Artery; Histamine; Male; Muscle, Smooth; Propranolol; Pyrilamine; Rats; Stress, Physiological | 1976 |
Role of H2-receptor antagonists in the feedback of histamine [proceedings].
Topics: Amine Oxidase (Copper-Containing); Anaphylaxis; Animals; Burimamide; Cyclic AMP; Feedback; Guinea Pigs; Histamine; Lung; Metiamide; Pyridines; Pyrilamine; Thiourea | 1977 |
Relationship between histamine-induced changes of cyclic AMP and mechanical activity on smooth muscle preparations of the guinea-pig ileum and the rabbit mesenteric artery.
Topics: Animals; Cyclic AMP; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Mesenteric Arteries; Metiamide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rabbits; Time Factors | 1979 |
Effect of intraventricular histamine on hormone secretion in dogs.
Topics: 11-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Animals; Blood Pressure; Dogs; Female; Heart Rate; Histamine; Injections, Intraventricular; Male; Methylhistamines; Metiamide; Prolactin; Pyrilamine | 1979 |
Reactivity of isolated bovine mesenteric and hepatic veins to vasoactive agents and specific antigen.
Topics: Acetylcholine; Anaphylaxis; Animals; Antigens; Atropine; Cattle; Dopamine; Dose-Response Relationship, Drug; Hepatic Veins; Histamine; Histamine H1 Antagonists; Horses; In Vitro Techniques; Isoproterenol; Kinetics; Male; Mesenteric Veins; Methysergide; Morphine; Norepinephrine; Phenylephrine; Pyrilamine; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 1975 |
Influence of antihistamine and compound 48/80 on healing.
Topics: Animals; Histamine; Histamine H1 Antagonists; p-Methoxy-N-methylphenethylamine; Pyrilamine; Rats; Skin; Wound Healing | 1975 |
The significance of histamine H1 and H2 receptors on the carotid vascular bed in the dog.
Topics: Animals; Blood Pressure; Burimamide; Carotid Arteries; Dogs; Histamine; Histamine H1 Antagonists; Metiamide; Pyrilamine; Receptors, Drug; Vascular Resistance; Vasomotor System | 1975 |
Characterization of the rabbit detrusor response to histamine through pharmacologic antagonism.
Topics: Animals; Atropine; Dose-Response Relationship, Drug; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Male; Metiamide; Muscle, Smooth; Phenoxybenzamine; Propantheline; Propranolol; Pyrilamine; Rabbits; Urinary Bladder | 1975 |
The possible roles of histamine, 5-hydroxytryptamine and prostaglandin F2alpha as mediators of the acute pulmonary effects of endotoxin.
Topics: Animals; Burimamide; Cats; Drug Interactions; Endotoxins; Escherichia coli; Female; Hemodynamics; Histamine; Lung; Male; Meclofenamic Acid; p-Methoxy-N-methylphenethylamine; Polyphloretin Phosphate; Prostaglandins F; Pyrilamine; Serotonin; Time Factors | 1977 |
Changes in blood flow and mediator content of rabbit skin grafts.
Topics: Animals; Histamine; Indomethacin; Prostaglandins; Pyrilamine; Rabbits; Regional Blood Flow; Skin; Skin Transplantation; Time Factors; Transplantation, Autologous | 1978 |
Anaphylaxis in guinea-pig peripheral airways in vitro.
Topics: Anaphylaxis; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomethacin; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins F; Pyrilamine; SRS-A; Trachea | 1979 |
The effects of mepyramine and cimetidine on the motor responses to histamine, cholecystokinin, and gastrin in the fundus and antrum of isolated guinea-pig stomachs.
Topics: Acetylcholine; Aminopyridines; Animals; Cholecystokinin; Cimetidine; Female; Gastrins; Gastrointestinal Motility; Guanidines; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Pressure; Pyloric Antrum; Pyrilamine | 1979 |
Comparison of the urinary bladder base and detrusor to cholinergic and histaminergic receptor activation in the rabbit.
Topics: Animals; Atropine; Carbachol; Histamine; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rabbits; Receptors, Cholinergic; Receptors, Histamine; Receptors, Histamine H1; Urinary Bladder | 1979 |
The relation between skin histamine concentration, histamine sensitivity, and the resistance of cattle to the tick, Boophilus microplus.
Topics: Allergens; Animals; Cattle; Histamine; Hypersensitivity, Immediate; Pyrilamine; Skin; Ticks | 1979 |
Histamine H1-and H2-receptors in coronary arteries of pigs.
Topics: Animals; Coronary Vessels; Histamine; In Vitro Techniques; Metiamide; Muscle Contraction; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine | 1979 |
Reactions of cultured human endothelial cells to certain autopharmacological substances.
Topics: Cells, Cultured; Endothelium; Histamine; Humans; Metiamide; Mitosis; Pyrilamine; Serotonin; Umbilical Veins | 1979 |
Histamine-induced increases in gastric blood flow in rats.
Topics: Animals; Blood Flow Velocity; Cimetidine; Histamine; Pyrilamine; Rats; Regional Blood Flow; Stomach; Vasodilator Agents | 1979 |
Coronary anaphylaxis in vitro.
Topics: Anaphylaxis; Animals; Atropine; Carbachol; Cattle; Coronary Vessels; Histamine; In Vitro Techniques; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Serotonin | 1979 |
An inhibitory action of histamine on the rat isolated vas deferens.
Topics: Animals; Cimetidine; Drug Interactions; Electric Stimulation; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Pyrilamine; Rats; Vas Deferens | 1979 |
Effect of histamine on the small arteries in the gracilis muscle of the rabbit.
Topics: Animals; Arteries; Cimetidine; Female; Histamine; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Muscles; Norepinephrine; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2 | 1979 |
Cutaneous vascular histamine H1 and H2 receptors in the guinea-pig: the histamine skin wheal as a cutaneous vascular model.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Metiamide; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Skin; Skin Tests | 1979 |
Comparison of the effects of histamine and serotonin on dynamic pulmonary compliance and pulmonary flow resistance in anesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Guinea Pigs; Histamine; Lung Compliance; Methysergide; Pulmonary Ventilation; Pyrilamine; Serotonin; Vagotomy | 1979 |
Stimulated efflux of tritiated noradrenaline and its metabolites from rabbit ear arteries-inhibition by histamine.
Topics: Animals; Arteries; Cocaine; Ear; Electric Stimulation; Histamine; In Vitro Techniques; Norepinephrine; Pyrilamine; Rabbits; Tritium | 1979 |
Pharmacological study of bovine airways. Evidence for excitatory and inhibitory effects of histamine.
Topics: Age Factors; Animals; Animals, Newborn; Atropine; Bradykinin; Bronchi; Carbachol; Cattle; Histamine; Metiamide; Propranolol; Prostaglandins F; Pyrilamine; Serotonin; Trachea | 1979 |
[Involvement of both H1- and H2-receptors in the depressor responses of blood pressure to histamine in the rat (author's transl)].
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Histamine; Male; Metiamide; Pyridines; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1977 |
Direct or indirect action of histamine on dopamine metabolism in the rat striatum?
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Histamine; Histidine; Homovanillic Acid; Pyrilamine; Rats; Time Factors; Tremorine | 1977 |
[Histamine receptors in the guinea pig papillary muscle].
Topics: Animals; Cimetidine; Epinephrine; Female; Guinea Pigs; Histamine; Male; Papillary Muscles; Pyrilamine; Receptors, Histamine; Thiazoles; Thiourea | 1977 |
Studies on the role of histamine and 5-hydroxytryptamine in immunity against the nematode Trichostrongylus colubriformis. IV. Inhibition of the expulsion of worms transplanted into the duodenum of immune guinea pigs.
Topics: Albuterol; Aminophylline; Animals; Female; Guinea Pigs; Histamine; Isoproterenol; Phenanthrolines; Propranolol; Pyrilamine; Pyrimidines; Serotonin; Triazoles; Trichostrongyloidiasis | 1978 |
H1- and H2-receptors in the smooth muscle of the ruminant stomach.
Topics: Animals; Cattle; Histamine; In Vitro Techniques; Metiamide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach, Ruminant | 1978 |
The effects of stimulants and inhibitors of histamine receptors on acid secretion from guinea pig gastric fundus.
Topics: Animals; Cimetidine; Female; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methylhistamines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Thiourea; Time Factors | 1978 |
Immunological response of the rat to infection with Taenia taeniaeformis. VI. The role of immediate hypersensitivity in resistance to reinfection.
Topics: Animals; Antibodies; Cyproheptadine; Histamine; Hypersensitivity, Immediate; Immunity, Maternally-Acquired; Immunization, Passive; Passive Cutaneous Anaphylaxis; Pyrilamine; Rats; Reagins; Serotonin; Taeniasis | 1978 |
Histamine receptors in mesenteric circulation of the cat and rat.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; Histamine; Histamine Antagonists; Infusions, Parenteral; Male; Mesenteric Arteries; Metiamide; Pyrilamine; Rats; Receptors, Histamine; Regional Blood Flow; Vascular Resistance | 1978 |
Spasmolytic action of histamine in airway smooth muscle of horse.
Topics: Animals; Atropine; Bronchi; Burimamide; Cimetidine; Histamine; Horses; In Vitro Techniques; Indomethacin; Metiamide; Muscle Contraction; Muscle, Smooth; Propranolol; Pyrilamine; Respiratory System; Trachea | 1978 |
Stimulation of cell proliferation by histamine H2 receptors in dimethylhdrazine-induced adenocarcinomata.
Topics: Adenocarcinoma; Animals; Cell Division; Cimetidine; Colon; Colonic Neoplasms; Dimethylhydrazines; Histamine; Intestinal Mucosa; Male; Metiamide; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Thiourea | 1978 |
Cardiovascular and antidiuretic effects of central histamine.
Topics: Animals; Blood Pressure; Diuresis; Drug Interactions; Heart Rate; Hemodynamics; Hexamethonium Compounds; Histamine; Infusions, Parenteral; Injections, Intraventricular; Male; Pyrilamine; Rats | 1978 |
Effect of histamine and related compounds on the papillary muscle of the guinea pig.
Topics: Animals; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Papillary Muscles; Pyrilamine; Structure-Activity Relationship; Verapamil | 1978 |
Effect of dimaprit on gastric acid secretion in conscious cats.
Topics: Animals; Cats; Cimetidine; Gastric Juice; Histamine; Methylhistamines; Pentagastrin; Pyrilamine; Receptors, Histamine H2; Thiourea; Time Factors | 1978 |
Central cardiovascular actions of histamine in rats: involvement of histamine H2-receptors.
Topics: Animals; Blood Pressure; Heart Rate; Histamine; Histamine Antagonists; Injections, Intraventricular; Male; Metiamide; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Tachycardia; Urethane | 1978 |
Effect of antihistamines and chlorpromazine on the calcium-induced hyperpolarization of the Amphiuma red cell membrane.
Topics: Animals; Biological Transport, Active; Calcimycin; Calcium; Cell Membrane Permeability; Chlorpromazine; Erythrocyte Membrane; Erythrocytes; Histamine; Membrane Potentials; Potassium; Promethazine; Pyridines; Pyrilamine; Urodela | 1976 |
Comparison of drug-induced responses of rabbit trachea and bronchus.
Topics: Aminophylline; Animals; Atropine; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Nitroglycerin; Papaverine; Phentolamine; Potassium Chloride; Prostaglandins; Pyrilamine; Rabbits; Trachea | 1976 |
Modification of cardiovascular responses to histamine by dithiothreitol.
Topics: Animals; Aorta; Arteries; Dithiothreitol; Drug Interactions; Hemodynamics; Histamine; Humans; In Vitro Techniques; Metiamide; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Norepinephrine; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Vasodilator Agents | 1977 |
Nature of histamine receptors concerned in capillary permeability.
Topics: Animals; Burimamide; Capillary Permeability; Drug Interactions; Female; Histamine; Male; Methylhistamines; Mice; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1977 |
Involvement of hypothalamic histamine-receptors in the central cardiovascular actions of histamine.
Topics: Animals; Atropine; Blood Pressure; Cerebral Ventricles; Heart Rate; Histamine; Hypothalamus; Male; Phentolamine; Pyrilamine; Rats; Receptors, Histamine | 1977 |
Histamine receptors in the isolated rat stomach fundus and rabbit aortic strips.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrointestinal Motility; Histamine; Methylhistamines; Metiamide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rabbits; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1977 |
Histamine receptors in the coronary circulation of the dog. Effects of mepyramine and metiamide on responses to histamine infusions.
Topics: Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Injections, Intra-Arterial; Metiamide; Myocardial Contraction; Pyridines; Pyrilamine; Receptors, Histamine; Thiourea; Time Factors | 1977 |
A study about the possible characteristics of cardiovascular histamine receptors of the turtle.
Topics: Animals; Blood Pressure; Female; Histamine; Male; Metiamide; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Reserpine; Turtles | 1977 |
Cholinergic link in the histamine-mediated increase in homovanillic acid in the rat striatum.
Topics: Animals; Atropine; Corpus Striatum; Dopamine; Female; Histamine; Homovanillic Acid; Kinetics; Male; Phenylacetates; Pyrilamine; Rats; Sex Factors | 1977 |
A comparison of the effects of bradykinin, 5-hydroxytryptamine and histamine on the hepatic arterial and portal venous vascular beds of the dog: histamine H1 and H2-receptor populations.
Topics: Animals; Blood Pressure; Bradykinin; Dogs; Drug Interactions; Hepatic Artery; Histamine; Liver Circulation; Metiamide; Portal Vein; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Serotonin; Vascular Resistance | 1977 |
Histamine, histamine antagonists and regional blood flow.
Topics: Animals; Blood Pressure; Cats; Drug Interactions; Female; Hemodynamics; Histamine; Male; Metiamide; Pyridines; Pyrilamine; Regional Blood Flow; Thiourea; Vascular Resistance | 1977 |
Vascular reactions to horseradish peroxidase in the guinea pig.
Topics: Animals; Capillary Permeability; Female; Guinea Pigs; Histamine; Histocytochemistry; Horseradish Peroxidase; Male; Peroxidases; Pyrilamine; Skin | 1977 |
N-methyl, 5-methyl histamine evokes a higher maximal rate of gastric acid secretion than histamine.
Topics: Animals; Cats; Gastric Juice; Histamine; Methylhistamines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Secretory Rate | 1977 |
Release of creatine kinase by antigen, histamine, and catecholamines.
Topics: Anaphylaxis; Animals; Antigens; Catecholamines; Creatine Kinase; Dibenzylchlorethamine; Epinephrine; Female; Guinea Pigs; Histamine; Male; Myocardium; Norepinephrine; Ovalbumin; Pyrilamine | 1976 |
Sites and mechanisms of action of histamine in the central thermoregulatory pathways of the rat.
Topics: Animals; Behavior, Animal; Benserazide; Body Temperature Regulation; Burimamide; Female; Histamine; Histidine; Pyrilamine; Rats; Receptors, Drug | 1976 |
Nature of histamine receptors in the emetic chemoreceptor trigger zone.
Topics: Animals; Burimamide; Chemoreceptor Cells; Dogs; Emetics; Female; Histamine; Injections, Intraventricular; Male; Metiamide; Pyrilamine; Receptors, Drug | 1976 |
Depression of rat cerebral cortical neurones by H1 and H2 histamine receptor agonists.
Topics: Acetylcholine; Animals; Cerebral Cortex; Guanidines; Histamine; Imidazoles; In Vitro Techniques; Male; Metiamide; Neurons; Norepinephrine; Pyridines; Pyrilamine; Rats; Receptors, Drug | 1976 |
Biphasic changes in body temperature produced by intracerebroventricular injections of histamine in the cat.
Topics: Animals; Body Temperature; Brain; Cats; Dose-Response Relationship, Drug; Histamine; Injections, Intraventricular; Metiamide; Pyrilamine; Temperature; Time Factors | 1976 |
[The effect of mepyramine and 48/80 on the histamine content of pleural exudates in the rat].
Topics: Animals; Carrageenan; Exudates and Transudates; Histamine; p-Methoxy-N-methylphenethylamine; Pleura; Pleurisy; Pyridines; Pyrilamine; Rats; Serotonin; Silver Nitrate; Time Factors; Turpentine | 1976 |
On the mechanism of the hypertensive action of intraseptal bradykinin in the rat.
Topics: Animals; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Injections; Male; Norepinephrine; Phentolamine; Pyrilamine; Rats; Septum Pellucidum; Time Factors | 1976 |
Adenylate cyclase of the dog gastric mucosa: stimulation by histamine and inhibition by metiamide.
Topics: Adenylyl Cyclases; Animals; Dogs; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Metiamide; Pyrilamine; Thiourea | 1976 |
Stimulation of adenylate cyclase of guinea pig gastric mucosa by histamine, sodium fluoride and 5'-guanylylimidodiphosphate and inhibition by histamine H1- and H2-receptor antagonists in vitro.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Diphenhydramine; Fluorides; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Metiamide; Pentagastrin; Phenylephrine; Pyrilamine; Sodium Fluoride | 1976 |
The mechanism of the vasodilator effects of histamine and 4-methylhistamine in the hindquarters of the cat.
Topics: Animals; Cats; Female; Histamine; Male; Methylhistamines; Metiamide; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Vasodilator Agents; Vasomotor System | 1976 |
Effect of urogastrone on gastric secretion and plasma gastrin levels in normal subjects.
Topics: Adult; Depression, Chemical; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gastric Juice; Gastric Mucosa; Gastrins; Gastrointestinal Hormones; Histamine; Humans; Insulin; Intrinsic Factor; Male; Pentagastrin; Pepsin A; Pyrilamine | 1975 |
Histamine receptors in the synovial microcirculation.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Histamine; Metiamide; Microcirculation; Pyrilamine; Radioisotopes; Receptors, Drug; Synovial Membrane; Xenon | 1975 |
Sensitivity of neonatal rabbit ileum to histamine.
Topics: Acetylcholine; Animals; Animals, Newborn; Female; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pyrilamine; Rabbits; Receptors, Drug | 1975 |
An analysis of the depressor responses to histamine in the cat and dog: involvement of both H1- and H2-receptors.
Topics: Animals; Blood Pressure; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Female; Histamine; Male; Metiamide; Pyrilamine; Receptors, Drug | 1975 |
The role of H1 and H2-receptors in the coronary vascular response to histamine of isolated perfused hearts of guinea-pigs and rabbits.
Topics: Animals; Blood Pressure; Burimamide; Coronary Vessels; Female; Guinea Pigs; Heart; Heart Rate; Histamine; In Vitro Techniques; Male; Muscle, Smooth; Pyrilamine; Receptors, Drug; Species Specificity; Time Factors | 1975 |
Cardiovascular histamine receptors in the domestic chicken.
Topics: Acetylcholine; Animals; Blood Pressure; Burimamide; Central Venous Pressure; Chickens; Depression, Chemical; Female; Hemodynamics; Histamine; Pyrilamine; Receptors, Drug | 1975 |
The response of the newborn rat to injury. I. Vascular and humoral aspects.
Topics: Age Factors; Albumins; Animals; Animals, Newborn; Bradykinin; Capillary Permeability; Carrageenan; Cathepsins; Cellulose; Cyproheptadine; Edema; Exudates and Transudates; Foot; Hindlimb; Histamine; Inflammation; Injections, Subcutaneous; Male; p-Methoxy-N-methylphenethylamine; Pleurisy; Prostaglandins E; Proteins; Pyrilamine; Rats; Serotonin; Sodium Chloride; Turpentine | 1975 |
Histamine receptors in peripheral vascular beds in the cat.
Topics: Animals; Blood Vessels; Cats; Female; Femoral Artery; Hindlimb; Histamine; Male; Mesenteric Arteries; Metiamide; Pyrilamine; Receptors, Drug; Regional Blood Flow; Vasomotor System | 1975 |
Proceedings: A comparison of the histopathological effects of anaphylatoxin (AT) and prostaglandins E2 (PGE2) and F2alpha (PGF2alpha) in guinea-pig lungs.
Topics: Anaphylaxis; Animals; Complement System Proteins; Guinea Pigs; Histamine; Lung; Peptide Fragments; Prostaglandins E; Prostaglandins F; Pyrilamine; Toxins, Biological | 1975 |
Histamine H1- and H2-receptors in the central thermoregulatory pathways of the rat.
Topics: Animals; Benserazide; Body Temperature Regulation; Brain Mapping; Burimamide; Cerebral Ventricles; Female; Histamine; Histidine; Hypothalamus; Pyrilamine; Rats; Receptors, Drug | 1975 |
The effect of mepyramine on the development of morphine tolerance and physical dependence in mice.
Topics: Animals; Brain Chemistry; Drug Tolerance; Female; Histamine; Humans; Male; Mice; Morphine; Morphine Dependence; Pyridines; Pyrilamine; Receptors, Drug | 1975 |
Identification and specific blockade of two receptors for histamine in the cardiovascular system.
Topics: Animals; Blood Pressure; Burimamide; Dogs; Female; Heart Rate; Hemodynamics; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscles; Myocardial Contraction; Pyrilamine; Receptors, Drug; Saphenous Vein; Stomach; Vasomotor System | 1976 |
Histamine receptors in the cat mesenteric circulation.
Topics: Animals; Cats; Chemotherapy, Cancer, Regional Perfusion; Dose-Response Relationship, Drug; Histamine; Ileum; Mesenteric Arteries; Metiamide; Pressure; Pyrilamine; Receptors, Drug | 1976 |
Comparative effects of four migraine prophylactic drugs on an isolated extracranial artery.
Topics: Animals; Carotid Artery, External; Chlorides; Clonidine; Cyproheptadine; Drug Interactions; Histamine; Methysergide; Norepinephrine; Phentolamine; Pizotyline; Potassium; Pyrilamine; Rabbits; Serotonin; Thiophenes; Tryptamines; Tyramine; Vasoconstrictor Agents | 1976 |
Central hypertensive action of histamine in conscious normotensive cats.
Topics: Animals; Behavior, Animal; Blood Pressure; Cats; Heart Rate; Histamine; Injections, Intraventricular; Metiamide; Pyrilamine; Stimulation, Chemical; Time Factors | 1976 |
Release of prostaglandins from healthy and sensitized guinea-pig lung and trachea by histamine.
Topics: Animals; Drug Interactions; Guinea Pigs; Histamine; Immunization; Lung; Male; Metiamide; Prostaglandins E; Prostaglandins F; Pyrilamine; Trachea | 1976 |
Possible role of histamine receptors in cardiovascular responses to 5-hydroxytryptamine in the chicken.
Topics: Acetylcholine; Animals; Burimamide; Chickens; Depression, Chemical; Female; Hemodynamics; Histamine; Pyrilamine; Receptors, Drug; Serotonin | 1976 |
Histamine receptors in esophageal smooth muscle of the opossum.
Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Esophagogastric Junction; Esophagus; Female; Histamine; Male; Metiamide; Muscle Contraction; Opossums; p-Methoxy-N-methylphenethylamine; Pyridines; Pyrilamine; Receptors, Drug | 1976 |
Antagonism of kinin effects on epithelial by Hoe 140: apparently competitive and non-competitive interactions.
Topics: Adenocarcinoma; Binding, Competitive; Bradykinin; Calcium; Chlorides; Colonic Neoplasms; Epithelium; Fura-2; Histamine; Humans; Ion Channels; Kallidin; Kinins; Pyrilamine; Tumor Cells, Cultured | 1992 |
The effects of histamine, pyrilamine, cimetidine, and ranitidine on secretion of lingual lipase and amylase from rat von Ebner's glands.
Topics: Amylases; Animals; Cimetidine; Exocytosis; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Lipase; Male; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Salivary Glands | 1992 |
Histamine leukocytosis. I. Effect of histamine on peripheral leukocyte counts.
Topics: Animals; Cimetidine; Dogs; Erythrocyte Count; Guanidines; Guinea Pigs; Histamine; Leukocyte Count; Leukocytosis; Osmolar Concentration; Pyrilamine; Rabbits; Waxes | 1992 |
Histamine and calcium are independently regulated intracellular mediators of lymphocyte mitogenesis.
Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cerebral Cortex; Cimetidine; Concanavalin A; DNA Replication; Histamine; Histamine Antagonists; Kinetics; Lymphocytes; Mice; Mice, Inbred BALB C; Phenyl Ethers; Pyrilamine; Rats; Receptors, Histamine H1; Receptors, Nicotinic; Spleen; Verapamil | 1992 |
Antigen-induced enhancement of noncholinergic contractile responses to vagus nerve and electrical field stimulation in guinea pig isolated trachea.
Topics: Animals; Antigens; Biphenyl Compounds; Capsaicin; Electric Stimulation; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Naloxone; Nerve Fibers; Neurokinin A; Peptide Fragments; Prostaglandin D2; Pyrilamine; Serotonin; Tetrodotoxin; Trachea; Vagus Nerve | 1992 |
[The effect of histamine on the levels of cyclic nucleotides in the nasal mucosa tissue of rats].
Topics: Animals; Cyclic AMP; Cyclic GMP; Histamine; Male; Nasal Mucosa; Pyrilamine; Rats; Rats, Wistar; Verapamil | 1992 |
Effect of histamine on signal transduction in cultured human trabecular meshwork cells.
Topics: Adult; Aged; Aged, 80 and over; Calcium; Cells, Cultured; Histamine; Histamine Antagonists; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Middle Aged; Phosphatidylinositols; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Trabecular Meshwork | 1992 |
Pharmacological evaluation of the histamine H1 and 5-HT blocking properties of 2-N-(carboxamidinonormianserin) (FCC5): in-vitro studies.
Topics: Animals; Electric Stimulation; Guinea Pigs; Heart Rate; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Male; Mianserin; Muscle Contraction; Muscle, Smooth; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stomach | 1992 |
Mechanism of nasal secretion mediated via nerve reflex in guinea pigs and evaluation of antiallergic drugs.
Topics: Allergens; Aminopyridines; Animals; Atropine Derivatives; Bronchodilator Agents; Capsaicin; Ganglionic Blockers; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hypersensitivity; Lidocaine; Methacholine Chloride; Nasal Mucosa; ortho-Aminobenzoates; Parasympatholytics; Phthalazines; Pyrilamine; Reflex | 1992 |
Histamine inhibits 5-hydroxytryptamine release from the porcine small intestine: involvement of H3 receptors.
Topics: Animals; Female; Histamine; Hydroxyindoleacetic Acid; In Vitro Techniques; Intestine, Small; Male; Methylhistamines; Pyrilamine; Receptors, Histamine; Serotonin; Swine | 1992 |
Mechanisms contributing to ozone-induced bronchial hyperreactivity in guinea-pigs.
Topics: Adenine Nucleotides; Animals; Ascorbic Acid; Atropine; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Fentanyl; Glutathione; Guinea Pigs; Histamine; Indomethacin; Lipoxygenase Inhibitors; Male; Neprilysin; Oligopeptides; Oxidation-Reduction; Ozone; Pyrilamine; Substance P; Vagus Nerve | 1992 |
Visualization of histamine binding to nuclei.
Topics: Animals; Binding Sites; Cell Membrane; Cell Nucleus; Cimetidine; Corpus Luteum; Endothelium, Vascular; Female; Granulosa Cells; Histamine; Microscopy, Fluorescence; Oocytes; Ovary; Pyrilamine; Rabbits; Staining and Labeling | 1992 |
Mast cells contribute to fibrin deposition in reverse passive Arthus reaction in mouse skin.
Topics: Animals; Arthus Reaction; Capillary Permeability; Fibrin; Histamine; Mast Cells; Mice; Pyrilamine; Skin | 1992 |
High dose of histamine required for gastric acid secretion in the common African toad, Bufo regularis.
Topics: Animals; Bufonidae; Carbachol; Cimetidine; Evaluation Studies as Topic; Gastric Acid; Gastric Acidity Determination; Histamine; Injections, Intramuscular; Pyrilamine; Time Factors | 1992 |
The effect of histamine on cultured endothelial cells. A study of the mechanism of increased vascular permeability.
Topics: Actins; Capillary Permeability; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Histamine; Humans; Pyrilamine | 1992 |
Histamine modulates heat stress-induced changes in blood-brain barrier permeability, cerebral blood flow, brain oedema and serotonin levels: an experimental study in conscious young rats.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature; Male; Organ Specificity; Pyrilamine; Rats; Rats, Wistar; Regional Blood Flow; Serotonin; Stress, Physiological | 1992 |
Relationship between histamine, lipoxygenase and cyclooxygenase products in antigen-induced contraction in guinea-pig tracheal tube preparations.
Topics: Animals; Antigens; Eicosanoids; Epithelium; Female; Guinea Pigs; Histamine; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Muscle Contraction; Muscle, Smooth; Propionates; Pyrilamine; Quinolines; Trachea | 1992 |
Responses of isolated human epigastric arteries to histamine.
Topics: Abdominal Muscles; Arteries; Diuretics; Endothelium; Female; Histamine; Histamine Antagonists; Humans; Hypertension; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pregnancy; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1992 |
Possible contributory role of the central histaminergic system in the forced swimming model.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Central Nervous System; Depressive Disorder; Disease Models, Animal; Histamine; Male; Maprotiline; Methylhistamines; Mice; Motor Activity; Pyrilamine; Swimming | 1992 |
Agonist-induced inositol phosphate responses in bovine airway submucosal glands.
Topics: Animals; Bradykinin; Carbachol; Cattle; Histamine; In Vitro Techniques; Inositol; Inositol Phosphates; Interleukin-1; Kinetics; Muscle, Smooth; Norepinephrine; Pyrilamine; Sodium Fluoride; Trachea; Tritium | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Histamine H1-receptors mediate endothelium-dependent relaxation of rat isolated pulmonary arteries.
Topics: Animals; Cimetidine; Endothelium, Vascular; Histamine; Indomethacin; Male; Muscle, Smooth, Vascular; Nitric Oxide; Phenylephrine; Pulmonary Artery; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Vasodilation | 1992 |
Histamine H1-receptor-mediated calcium influx in DDT1MF-2 cells.
Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cations, Divalent; Cell Line; Cricetinae; Histamine; Male; Manganese; Muscle, Smooth; Nickel; Pyrilamine; Receptors, Histamine H1; Vas Deferens | 1992 |
Further investigations on the antipropulsive effect of centrally administered histamine and its relation with morphine.
Topics: Animals; Fasting; Female; Gastrointestinal Motility; Gastrointestinal Transit; Histamine; Injections, Intraventricular; Jejunum; Morphine; Norepinephrine; Oxidopamine; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1992 |
The effects of (R) alpha-methyl histamine on the isolated guinea pig aorta.
Topics: Animals; Aorta; Cimetidine; Female; Guanidines; Guinea Pigs; Histamine; Histamine Antagonists; Imidazoles; Impromidine; Male; Methylhistamines; Muscle, Smooth, Vascular; Potassium; Pyrilamine; Receptors, Histamine; Receptors, Histamine H3; Vasoconstriction; Vasodilation | 1991 |
Antigen-induced mediator release in primates.
Topics: Administration, Inhalation; Airway Resistance; Animals; Antigens; Ascaris; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cell Count; Chromatography, High Pressure Liquid; Dexamethasone; Histamine; Leukotriene B4; Leukotrienes; Lipids; Lung Compliance; Macaca fascicularis; Male; Prostaglandin D2; Prostaglandins; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Thromboxane B2 | 1991 |
Characterization of histamine receptors modulating inotropic and biochemical activities in rabbit left atria.
Topics: Animals; Atrial Function; Cardiotonic Agents; Cimetidine; Female; Heart; Heart Atria; Histamine; Hydrolysis; Inositol Phosphates; Male; Myocardial Contraction; Phosphatidylinositols; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Stimulation, Chemical; Tritium | 1991 |
Homologous histamine H1 receptor desensitization results in reduction of H1 receptor agonist efficacy.
Topics: Animals; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Jejunum; Male; Membranes; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Pyridines; Pyrilamine; Receptors, Histamine H1; Tritium | 1991 |
Anomalous responses to histamine stimulation of guinea-pig oesophageal muscularis mucosae.
Topics: Animals; Atropine; Drug Tolerance; Esophagus; Guinea Pigs; Histamine; Lidocaine; Methysergide; Mucous Membrane; Muscle Contraction; Physostigmine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Tetrodotoxin | 1991 |
Characterization of histamine-induced contraction in rat isolated aorta.
Topics: Animals; Aorta, Thoracic; Cyclic GMP; Endothelium, Vascular; Histamine; In Vitro Techniques; Male; Nitric Oxide; Phentolamine; Prazosin; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Histamine H1; Vasoconstriction | 1991 |
Increase in intracellular calcium induced by stimulating histamine H1 receptors in macrophage-like P388D1 cells.
Topics: Animals; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Fura-2; Histamine; Kinetics; Leukemia P388; Macrophages; Microscopy, Fluorescence; Pyrilamine; Receptors, Histamine H1 | 1991 |
Histamine-induced cyclic AMP accumulation in type-1 and type-2 astrocytes in primary culture.
Topics: Animals; Astrocytes; Cells, Cultured; Cyclic AMP; Famotidine; Histamine; Kinetics; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Stimulation, Chemical | 1991 |
Histamine-induced inositol phosphate accumulation in HeLa cells: lithium sensitivity.
Topics: Fluorides; HeLa Cells; Histamine; Humans; Inositol Phosphates; Lithium; Phosphoric Monoester Hydrolases; Pyrilamine | 1991 |
Optical isomers of rocastine and close analogues: synthesis and H1 antihistaminic activity of its enantiomers and their structural relationship to the classical antihistamines.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Drug Design; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Isomerism; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazepines; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship | 1991 |
Effects of thioperamide, a histamine H3 receptor antagonist, on locomotor activity and brain histamine content in mast cell-deficient W/Wv mice.
Topics: Animals; Benzothiazoles; Brain Chemistry; Dopamine; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Mast Cells; Methylhistamines; Mice; Mice, Mutant Strains; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine H3; Thiazoles | 1991 |
Histamine H1-receptors on astrocytes in primary cultures: a possible target for histaminergic neurones.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Histamine; Histamine H1 Antagonists; Inositol Phosphates; Neurons; Pyrilamine; Rats; Receptors, Histamine H1; Tetradecanoylphorbol Acetate | 1991 |
The effect of cetirizine on the human isolated bronchus: interaction with salbutamol.
Topics: Acetylcholine; Albuterol; Bronchi; Bronchoconstriction; Cetirizine; Dose-Response Relationship, Drug; Drug Synergism; Epithelium; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; In Vitro Techniques; Pyrilamine | 1991 |
Cyclic AMP generating systems in vertebrate retina: effects of histamine and an established retinal modulator, dopamine.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Chickens; Cimetidine; Colforsin; Cyclic AMP; Dimaprit; Dopamine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Retina; Thiazoles; Thiourea | 1991 |
Role of the endothelium and smooth muscle tone in the dilator response of the rabbit coeliac artery to histamine.
Topics: Animals; Celiac Artery; Endothelium, Vascular; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Muscle, Smooth, Vascular; Prazosin; Pyrilamine; Rabbits; Receptors, Histamine; Tachyphylaxis; Vasodilation | 1991 |
Effects of histamine H1-receptor blockade on respiratory and cardiac manifestation of systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Gas Analysis; Electrocardiography; Female; Guinea Pigs; Heart; Heart Ventricles; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Ovalbumin; Pyrilamine; Respiration | 1991 |
Recombinant human C5a-induced bronchoconstriction in the guinea pig: inhibition by an H1 antagonist after depletion of circulating granulocytes and platelets.
Topics: Animals; Blood Platelets; Blood Pressure; Bronchoconstriction; Complement C5a; Granulocytes; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Leukocyte Count; Male; Platelet Count; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Receptor, Anaphylatoxin C5a; Receptors, Complement; Recombinant Proteins | 1991 |
Effects of capsaicin treatment on immunoglobulin secretion in the rat: further evidence for involvement of tachykinin-containing afferent nerves.
Topics: Animals; Antigen-Presenting Cells; Capsaicin; Cell Count; Female; Histamine; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Kinetics; Neurons, Afferent; Pyrilamine; Rats; Rats, Inbred Strains; Substance P; Tachykinins | 1990 |
Does intracellular histamine mediate mast cell histamine release?
Topics: Animals; Cell Membrane Permeability; Cimetidine; Concanavalin A; Histamine; Histamine Release; In Vitro Techniques; Male; Mast Cells; Phosphatidylserines; Pyrilamine; Rats; Rats, Inbred Strains; Saponins | 1990 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles | 1990 |
Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brompheniramine; Cells, Cultured; Chromatography, High Pressure Liquid; Cimetidine; Cycloheximide; Dinoprostone; Dose-Response Relationship, Radiation; Eicosanoids; Epidermis; Erythema; Histamine; Histamine Release; Humans; In Vitro Techniques; Keratinocytes; Prostaglandins; Pyrilamine; Radiation Injuries, Experimental; Time Factors; Ultraviolet Rays | 1990 |
Histamine acts directly on calcitonin gene-related peptide- and substance P-containing trigeminal ganglion neurons as assessed by calcium influx and immunocytochemistry.
Topics: Animals; Calcitonin Gene-Related Peptide; Calcium; Cells, Cultured; Cimetidine; Fura-2; Histamine; Immunohistochemistry; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Substance P; Trigeminal Ganglion | 1990 |
A comparative study of histamine and K+ effects on (Ca(2+)-Mg2+)-ATPase activity in synaptosomes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Ca(2+) Mg(2+)-ATPase; Calcium Chloride; Calcium-Transporting ATPases; Cell Membrane; Choline; Diltiazem; Dose-Response Relationship, Drug; Histamine; Potassium; Pyrilamine; Ranitidine; Rats; Sodium; Synapses; Synaptosomes; Verapamil | 1991 |
A place for free radicals in platelet-derived histamine releasing factor (PDHRF) and evidence that histaminergic receptors modulate platelet aggregation.
Topics: Animals; Blood Platelets; Cell Membrane; Free Radical Scavengers; Free Radicals; Histamine; Histamine Release; Humans; Lipid Peroxidation; Male; Malondialdehyde; Mast Cells; Platelet Aggregation; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1 | 1991 |
Pharmacologic evaluation of A23187-induced contractions of three distinct preparations of guinea pig lung parenchymal strips.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcimycin; Drug Interactions; Guinea Pigs; Histamine; Hydroxyurea; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A | 1992 |
Histamine receptors in the isolated human middle meningeal artery. A comparison with cerebral and temporal arteries.
Topics: Adult; Cerebral Arteries; Cimetidine; Dose-Response Relationship, Drug; Drug Combinations; Female; Histamine; Humans; In Vitro Techniques; Male; Meningeal Arteries; Middle Aged; Osmolar Concentration; Pyrilamine; Receptors, Histamine; Temporal Arteries; Vasodilation | 1991 |
Interleukin-1 (IL-1) stimulates the release of corticotropin-releasing factor (CRF) from superfused rat hypothalamo-neurohypophyseal complexes (HNC) independently of the histaminergic mechanism.
Topics: Animals; Cimetidine; Corticotropin-Releasing Hormone; Histamine; Histamine Antagonists; Hypothalamo-Hypophyseal System; In Vitro Techniques; Interleukin-1; Male; Median Eminence; Perfusion; Pyrilamine; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
The interaction of acetylcholine and histamine on human bronchial smooth muscle contraction.
Topics: Acetylcholine; Asthma; Atropine; Bronchi; Dose-Response Relationship, Drug; Drug Interactions; Epithelium; Histamine; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Pyrilamine | 1991 |
Effects of histamine on spontaneous electrical activity of neurons in rat suprachiasmatic nucleus.
Topics: Action Potentials; Animals; Cimetidine; Circadian Rhythm; Histamine; Male; Neurons; Pyrilamine; Rats; Rats, Inbred Strains; Suprachiasmatic Nucleus | 1991 |
Histamine induces endothelium-dependent relaxation of bovine retinal arteries.
Topics: Acetylcholine; Animals; Cattle; Cimetidine; Dimaprit; Endothelium, Vascular; Histamine; Muscle Relaxation; Pyridines; Pyrilamine; Receptors, Histamine; Retinal Artery; Tachyphylaxis; Thiourea | 1991 |
Inhibition of endothelin-induced bronchoconstriction by OKY-046, a selective thromboxane A2 synthetase inhibitor, in guinea pigs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Bridged Bicyclo Compounds; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chromones; Endothelins; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine; Indomethacin; Male; Methacrylates; Pyrilamine; Thromboxane B2; Thromboxane-A Synthase | 1991 |
Studies on heterocyclic compounds: 1,3-thiazolidin-4-one derivatives. V. Pharmacological activity of substituted 2-phenyl-3-(N,N-dimethylaminoprophyl)-1,3-thiazolidin-4-one .
Topics: Animals; Female; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Schiff Bases; Structure-Activity Relationship; Thiazoles; Thiazolidines | 1991 |
5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools.
Topics: Biological Transport; Blotting, Northern; Down-Regulation; GTP-Binding Proteins; HeLa Cells; Histamine; Humans; Hydrolysis; Kinetics; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphates; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Receptors, Serotonin; RNA, Messenger; Serotonin; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 1991 |
Single type-2 astrocytes show multiple independent sites of Ca2+ signaling in response to histamine.
Topics: Animals; Astrocytes; Calcium; Calcium Channels; Chlorpheniramine; Fluorescent Dyes; Fura-2; Histamine; Inositol 1,4,5-Trisphosphate; Kinetics; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Signal Transduction | 1991 |
Eicosanoid release and mepyramine, LTC4 and LTD4 binding in passively sensitized human lung parenchyma in vitro.
Topics: Animals; Eicosanoids; Guinea Pigs; Histamine; Humans; Immunization, Passive; Immunoglobulin E; In Vitro Techniques; Lung; Muscle, Smooth; Prostaglandin D2; Pyrilamine; Receptors, Histamine H1; SRS-A | 1991 |
The intracerebroventricularly administered mast cells degranulator compound 48/80 increases the pituitary-adrenocortical activity in rats.
Topics: Adrenal Cortex; Animals; Brain; Cimetidine; Corticosterone; Cytoplasmic Granules; Histamine; Hypothalamus; Kinetics; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pituitary Gland; Pyrilamine; Rats; Rats, Inbred Strains; Thalamus | 1991 |
Is the airway epithelium responsible for histamine metabolism in the trachea of guinea pigs?
Topics: Amine Oxidase (Copper-Containing); Animals; Antigens; Epithelium; Female; Guanidines; Guinea Pigs; Histamine; Methylhistamines; Muscle Contraction; Ovalbumin; Pyrilamine; Trachea | 1991 |
Histamine-stimulated increases in intracellular calcium in the smooth muscle cell line, DDT1MF-2.
Topics: Animals; Calcium; Cell Line; Cricetinae; Histamine; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Stimulation, Chemical | 1991 |
Histamine augments colonic secretion in guinea pig distal colon.
Topics: 2-Chloroadenosine; Animals; Bradykinin; Bumetanide; Chlorides; Cimetidine; Colon; Dinoprostone; Electric Stimulation; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; In Vitro Techniques; Indomethacin; Kinetics; Male; Masoprocol; Muscle, Smooth; Piroxicam; Pyrilamine; Tetrodotoxin; Vasoactive Intestinal Peptide | 1990 |
Kinetics of antagonism at histamine-H1 receptors in isolated rabbit arteries.
Topics: Animals; Antazoline; Arteries; Brompheniramine; Female; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Male; Muscle, Smooth, Vascular; Pyrilamine; Rabbits | 1990 |
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Male; Muscle Contraction; Piperidines; Pirenzepine; Potassium; Pyrilamine; Receptors, Muscarinic | 1990 |
Histamine stimulation of mucociliary activity in the rabbit maxillary sinus.
Topics: Animals; Atropine; Cilia; Cimetidine; Dimaprit; Female; Histamine; Histamine H2 Antagonists; Male; Maxillary Sinus; Mucociliary Clearance; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Muscarinic; Thiourea | 1990 |
Histamine lipolysis I: changes in the free fatty acid levels of dog plasma after intravenous infusion of histamine.
Topics: Aminophylline; Animals; Chromatography, High Pressure Liquid; Diphenhydramine; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Infusions, Intravenous; Lipolysis; Male; Methylhistamines; Pentobarbital; Pyrilamine; Starvation | 1990 |
Effects of histamine on protein and glycoprotein production of isolated pig gastric mucosal cells.
Topics: 16,16-Dimethylprostaglandin E2; Acetylglucosamine; Animals; Colforsin; Gastric Mucosa; Glycoproteins; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Leucine; Protein Biosynthesis; Pyrilamine; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Tritium | 1990 |
Pharmacology of the new H1-receptor antagonist setastine hydrochloride.
Topics: Animals; Azepines; Behavior, Animal; Binding, Competitive; Bronchi; Capillary Permeability; Cats; Central Nervous System Depressants; Clemastine; Female; Gastric Acid; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Passive Cutaneous Anaphylaxis; Pyrilamine; Rats; Serotonin Antagonists | 1990 |
Central nervous system histamine regulates peripheral sympathetic activity.
Topics: Animals; Arginine Vasopressin; Central Nervous System; Histamine; Histidine Decarboxylase; Male; Methylhistidines; Norepinephrine; Peripheral Nerves; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Sympathetic Nervous System | 1991 |
Antigen-induced release of airway epithelium-derived inhibitory factor.
Topics: Animals; Antigens; Biological Factors; Dose-Response Relationship, Immunologic; Endothelium, Vascular; Epithelium; Guinea Pigs; Histamine; Immunization; Leukotrienes; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; p-Methoxy-N-methylphenethylamine; Pyrilamine; Rats; Rats, Inbred Strains; SRS-A; Trachea | 1991 |
The participation of histaminergic receptors of the rostral hypothalamus on the tonic release of luteinizing hormone (LH) in adult spayed rats under estrogen and progesterone treatment.
Topics: Animals; Drug Interactions; Estradiol; Female; Histamine; Hypothalamo-Hypophyseal System; Hypothalamus, Anterior; Luteinizing Hormone; Methylhistidines; Metiamide; Ovariectomy; Pituitary Gland, Anterior; Progesterone; Pyrilamine; Rats; Receptors, Histamine; Secretory Rate | 1991 |
Histamine-induced changes in intracellular calcium in undifferentiated N1E-115 cells.
Topics: Animals; Bradykinin; Calcium; Cell Differentiation; Cell Line; Cimetidine; Histamine; Kinetics; Mice; Neuroblastoma; Pyrilamine; Signal Transduction | 1991 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Histamine-induced inositol phosphate accumulation in type-2 astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Chlorpheniramine; Famotidine; Histamine; Inositol Phosphates; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine | 1991 |
Characteristics of histamine-induced inositol phospholipid hydrolysis in HeLa cells.
Topics: Carbachol; HeLa Cells; Histamine; Humans; Hydrolysis; Inositol Phosphates; Kinetics; Pyrilamine; Receptors, Histamine H1 | 1991 |
The significance of brain histamine and its receptors in opioid stimulation of the pituitary-adrenocortical activity.
Topics: Adrenal Cortex; Animals; beta-Endorphin; Brain; Cimetidine; Corticosterone; Endorphins; Enkephalin, Leucine-2-Alanine; Histamine; Histidine Decarboxylase; Male; Morphine; p-Methoxy-N-methylphenethylamine; Pituitary Gland; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine | 1991 |
Role of histamine in pathophysiology of heat stress in rats.
Topics: Animals; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature; Male; Pyrilamine; Rats; Stress, Physiological | 1991 |
Effect of histamine on human placental chorionic veins: interaction with serotonin.
Topics: Chorion; Cimetidine; Drug Interactions; Female; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Placenta; Pregnancy; Pyrilamine; Serotonin; Veins | 1991 |
Alterations in histamine receptors of guinea-pig ileal smooth muscle produced during agonist-induced desensitization.
Topics: Animals; Female; Guanosine Triphosphate; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Kinetics; Male; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1 | 1990 |
Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.
Topics: Aminoquinolines; Animals; Bradykinin; Calcimycin; Calcium; Cimetidine; Endothelium, Vascular; Guinea Pigs; Histamine; Histamine Antagonists; Isoproterenol; Platelet Activating Factor; Pyrilamine; Vena Cava, Inferior | 1990 |
Allergen-induced biphasic bronchoconstriction in rats.
Topics: Airway Resistance; Allergens; Aminophylline; Animals; Bronchial Spasm; Chromones; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Histamine; Hypersensitivity; Leukotrienes; Male; Methacrylates; Methysergide; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Thromboxane B2; Time Factors | 1990 |
Mechanism of action of doxepin in the treatment of chronic urticaria.
Topics: Adult; Aged; Animals; Atropine; Carbachol; Chronic Disease; Dimaprit; Doxepin; Female; Gastric Juice; Guinea Pigs; Heart; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pylorus; Pyrilamine; Rats; Thiourea; Urticaria | 1990 |
H2 receptors mediate cyclical chloride secretion in guinea pig distal colon.
Topics: Animals; Bumetanide; Chlorides; Cimetidine; Colon; Dimaprit; Guinea Pigs; Histamine; In Vitro Techniques; Intestinal Mucosa; Kinetics; Male; Muscle, Smooth; Pyrilamine; Receptors, Histamine H2; Tetrodotoxin; Thiourea | 1990 |
A selective role for brain histamine in prolactin release induced by opiates.
Topics: Animals; beta-Endorphin; Brain Chemistry; Histamine; Injections, Intraventricular; Male; Methylhistidines; Prolactin; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains | 1990 |
Antagonistic effect of naloxone on the hypertensive response of intraventricularly administered histamine.
Topics: Animals; Blood Pressure; Cimetidine; Dimaprit; Hemodynamics; Histamine; In Vitro Techniques; Injections, Intraventricular; Male; Naloxone; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Thiourea | 1990 |
Binding sites for histamine and sulfidopeptide leukotrienes in normal and hypersensitized human lung fragments.
Topics: Binding Sites; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Lung; Prostaglandin D2; Pyrilamine; SRS-A | 1990 |
Endothelium and mechanical responses of isolated monkey pulmonary veins to histamine.
Topics: Animals; Dimaprit; Endothelium, Vascular; Famotidine; Hemoglobins; Histamine; In Vitro Techniques; Macaca; Methylene Blue; Pulmonary Veins; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea; Vasoconstriction; Vasodilation | 1990 |
Histamine stimulation of surfactant secretion from rat type II pneumocytes.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Cells, Cultured; Cimetidine; Cyclic AMP; Histamine; Isoproterenol; Kinetics; Lung; Male; Phosphatidylcholines; Pulmonary Surfactants; Pyrilamine; Rats; Rats, Inbred Strains | 1990 |
Histamine H3 receptors modulate antigen-induced bronchoconstriction in guinea pigs.
Topics: Animals; Antigens; Bronchoconstriction; Cimetidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Guinea Pigs; Histamine; Immunization; Male; Ovalbumin; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Skin Tests | 1990 |
Histamine receptors in brain vessels of guinea-pig: in-vitro pharmacology and ligand binding.
Topics: Animals; Basilar Artery; Brain; Calcium; Calcium Channels; Cerebrovascular Circulation; Chlorpheniramine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Ligands; Nimodipine; Pyrilamine; Receptors, Histamine; Vasoconstriction | 1990 |
Histamine H1-receptor of vascular endothelial cells cultured from guinea pig skin.
Topics: Animals; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Fluorescent Antibody Technique; Guinea Pigs; Histamine; Male; Microscopy, Phase-Contrast; Pyrilamine; Receptors, Histamine H1; Skin; Tritium | 1990 |
gamma-Aminobutyric acid inhibition of histamine-induced inositol phosphate formation in guinea-pig cerebellum: comparison with guinea-pig and rat cerebral cortex.
Topics: Animals; Binding, Competitive; Cerebellum; Cerebral Cortex; Endothelins; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Lithium; Male; Phospholipids; Pyrilamine; Rats; Rats, Inbred Strains; Species Specificity | 1990 |
Different histamine actions in proximal and distal human coronary arteries in vitro.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Cimetidine; Coronary Vessels; Culture Techniques; Endothelium, Vascular; Female; Histamine; Histamine Antagonists; Humans; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrilamine; Receptors, Histamine | 1990 |
Histamine acting on a histamine type 1 (H1) receptor increases beta-glucuronidase release from human lung macrophages.
Topics: Adult; Binding, Competitive; Cell Membrane; Dose-Response Relationship, Drug; Female; Glucuronidase; Histamine; Humans; Lung; Macrophages; Male; Pyrilamine; Receptors, Histamine H1; Smoking | 1990 |
Pharmacological characterization of mediators and vagal influence in the acute allergic bronchoconstriction in guinea pigs.
Topics: Adenosine; Animals; Bronchoconstriction; Dexamethasone; Diethylcarbamazine; Dipyridamole; Eicosanoic Acids; Female; Guinea Pigs; Histamine; Indomethacin; Male; Neural Pathways; Ovalbumin; Pyrilamine; Respiratory Hypersensitivity; Vagotomy; Vagus Nerve | 1990 |
Histamine receptors in human fibroblasts: inositol phosphates, Ca2+, and cell growth.
Topics: Aminopyridines; Calcium; Cell Division; Cell Line; DNA Replication; Fibroblasts; Fluorescent Dyes; Histamine; Humans; Inositol Phosphates; Kinetics; Phorbol 12,13-Dibutyrate; Pyrilamine; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate; Thymidine | 1990 |
Effect of histamine and 1,4-methylhistamine on gastric vascular resistance in dogs.
Topics: Animals; Cimetidine; Dogs; Female; Histamine; Kinetics; Male; Methylhistamines; Muscle, Smooth; Perfusion; Pyrilamine; Regional Blood Flow; Stomach; Time Factors; Vascular Resistance | 1990 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats | 1990 |
Assessment of vascular permeability increase in the mouse by dye leakage during paw edema.
Topics: Animals; Bradykinin; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Edema; Foot; Histamine; Male; Mice; Mice, Inbred ICR; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Tetradecanoylphorbol Acetate | 1990 |
Histamine excites pedunculopontine neurones in guinea pig brainstem slices.
Topics: Action Potentials; Aminopyridines; Animals; Guinea Pigs; Histamine; In Vitro Techniques; Pons; Pyrilamine; Receptors, Histamine; Tetrodotoxin | 1990 |
Mast cell chymase potentiates histamine-induced wheal formation in the skin of ragweed-allergic dogs.
Topics: Allergens; Animals; Capillary Permeability; Cell Degranulation; Chymases; Dogs; Histamine; Hypersensitivity; Mast Cells; p-Methoxy-N-methylphenethylamine; Pyrilamine; Serine Endopeptidases; Serine Proteinase Inhibitors; Skin Tests; Time Factors; Trypsin Inhibitors | 1990 |
Inhibition of human skin fibroblast proliferation by histamine and phorbol esters is mediated by protein kinase C.
Topics: Blood; Cell Division; Cell Line; Cimetidine; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Fibroblasts; Histamine; Humans; Phorbol Esters; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Thymidine | 1990 |
Effect of histamine on human bronchial arteries in vitro.
Topics: Adult; Bronchial Arteries; Cimetidine; Dinoprost; Histamine; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrilamine | 1990 |
Analysis of the factor(s) involved in pathogenesis of zymosan-induced inflammation in rats.
Topics: Animals; Capillary Permeability; Complement System Proteins; Histamine; Histamine Release; Inflammation; Male; Mast Cells; Methysergide; p-Methoxy-N-methylphenethylamine; Proteins; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Zymosan | 1985 |
H1-histamine receptors on human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; GTP-Binding Proteins; Histamine; Humans; Pertussis Toxin; Phosphatidylinositols; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Triprolidine; Tritium; Virulence Factors, Bordetella | 1986 |
Histamine involvement in the local and systemic microvascular effects produced by intradermal substance P.
Topics: Animals; Body Temperature; Capillary Permeability; Cimetidine; Dose-Response Relationship, Drug; Ear; Guinea Pigs; Histamine; Injections, Intradermal; Male; Pyrilamine; Receptors, Histamine; Skin; Substance P | 1985 |
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Atropine; Cimetidine; Cocaine; Cyclic AMP; Dinoprost; Histamine; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Propranolol; Prostaglandins F; Pyrilamine; Serotonin; Serotonin Antagonists; Swine; Vena Cava, Inferior | 1986 |
Experimental renal anaphylaxis: release of histamine and study of its effect on renal perfusion.
Topics: Anaphylaxis; Animals; Cimetidine; Guinea Pigs; Histamine; Histamine Release; Immune Sera; Immunoglobulin G; Kidney; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Renal Circulation | 1987 |
Autoinhibition of histamine synthesis mediated by presynaptic H3-receptors.
Topics: Animals; Burimamide; Cerebral Cortex; Cimetidine; Histamine; Histamine Release; Hypothalamus; Hypothalamus, Posterior; Imidazoles; Impromidine; Male; Potassium; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H3; Synaptosomes; Thiazoles | 1987 |
A pharmacologic study on the histamine releasing effect of atracurium and other muscle relaxants in rat isolated ileum.
Topics: Animals; Atracurium; Drug Interactions; Histamine; Histamine Release; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1987 |
The effects of substance P, histamine and histamine antagonists on somatostatin and gastrin release from the isolated perfused rat stomach.
Topics: Animals; Cimetidine; Gastric Mucosa; Gastrins; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Pyrilamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin; Substance P | 1987 |
Enhanced airway responses to substance P after repeated challenge in guinea pigs.
Topics: Animals; Atropine; Capsaicin; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Lung Compliance; Male; Muscle Contraction; Pyrilamine; Respiratory Physiological Phenomena; Respiratory System; Substance P | 1989 |
Substance P induced hydrolysis of inositol phospholipids in rat skin in an in vivo model of inflammation.
Topics: Animals; Blister; Capillary Permeability; Capsaicin; Histamine; Hydrolysis; Inflammation; Phosphatidylinositols; Pyrilamine; Rats; Skin; Substance P | 1989 |
Changing sensitivity to H1 and H2 receptor antagonists in the growing vasculature.
Topics: Animals; Blood Flow Velocity; Blood Vessels; Capillary Permeability; Cimetidine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Neovascularization, Pathologic; Prostheses and Implants; Pyrilamine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1988 |
Endothelium-dependent relaxations to histamine in the rat common carotid, renal and cranial mesenteric artery.
Topics: Acetylcholine; Animals; Carotid Arteries; Endothelium, Vascular; Female; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; Pyrilamine; Rats; Renal Artery; Vasodilation | 1988 |
Histamine directly gates a chloride channel in lobster olfactory receptor neurons.
Topics: Animals; Chloride Channels; Chlorides; Electric Conductivity; Evoked Potentials; Histamine; In Vitro Techniques; Ion Channels; Membrane Proteins; Nephropidae; Neurons; Pyrilamine; Sensory Receptor Cells; Smell | 1989 |
Inhibition of immunological histamine release from guinea pig lungs and other organs by mepyramine, ketotifen, and picumast in vivo.
Topics: Aminopyridines; Anaphylaxis; Animals; Coumarins; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Ketotifen; Lung; Male; Pyrilamine | 1989 |
Spontaneous rhythmic contractions of human saphenous veins isolated from old subjects are sensitive to cyclooxygenase inhibitors.
Topics: Adult; Aged; Aging; Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Female; Histamine; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle Development; Muscle, Smooth; Nifedipine; Norepinephrine; Phentolamine; Prazosin; Pyrilamine; Saphenous Vein | 1989 |
Short-term desensitization of phosphatidylinositol turnover via muscarinic acetylcholine receptors and histamine H1-receptors in smooth muscle.
Topics: Animals; Atropine; Carbachol; Colon; Egtazic Acid; Female; Guinea Pigs; Histamine; Inositol Phosphates; Male; Muscle, Smooth; Phosphatidylinositols; Pyrilamine; Receptors, Histamine H1; Receptors, Muscarinic | 1989 |
Pharmacological characterization of histamine receptors in the human temporal artery.
Topics: Adult; Cimetidine; Dinoprost; Female; Histamine; Humans; Imidazoles; Impromidine; In Vitro Techniques; Male; Methylhistamines; Middle Aged; Pyridines; Pyrilamine; Receptors, Histamine; Temporal Arteries; Thiazoles; Vasoconstriction; Vasodilation | 1989 |
Role of histamine receptor in mesencephalic nucleus dorsalis raphe in cardiovascular regulation.
Topics: Animals; Cardiovascular Physiological Phenomena; Cats; Cimetidine; Decerebrate State; Female; Fenclonine; Guanethidine; Histamine; Histamine Antagonists; Male; Mesencephalon; Microinjections; Piperoxan; Pyrilamine; Raphe Nuclei; Receptors, Histamine; Vagotomy | 1989 |
Effect of histamine on isolated working guinea pig heart with left ventricular hypertrophy produced by pressure overload.
Topics: Animals; Cardiomegaly; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Heart Function Tests; Histamine; In Vitro Techniques; Male; Norepinephrine; Pyrilamine; Receptors, Histamine H2 | 1989 |
Antagonistic action of naloxone on central histamine receptors-stimulated corticosterone secretion in rats under stress.
Topics: Animals; Cimetidine; Corticosterone; Dimaprit; Histamine; Male; Methylhistamines; Naloxone; Pituitary-Adrenal System; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Restraint, Physical; Stress, Physiological; Thiourea | 1989 |
Evidence indicating that leukotrienes C4, D4 and E4 are major mediators of contraction induced by anti-IgE in human bronchi.
Topics: Acetylcholine; Antibodies, Anti-Idiotypic; Bronchi; Histamine; Humans; Immunoglobulin E; Keto Acids; Leukotriene E4; Leukotrienes; Metiamide; Muscle Contraction; Phenylbutyrates; Pyrilamine; SRS-A; Sulfones | 1989 |
Influx of bivalent cations can be independent of receptor stimulation in human endothelial cells.
Topics: Calcium; Calcium Channels; Endothelium, Vascular; Extracellular Space; Histamine; Humans; Manganese; Pyrilamine; Receptors, Histamine | 1989 |
Demonstration of histamine receptors on the surface of Entamoeba histolytica.
Topics: Animals; Cimetidine; Entamoeba histolytica; Histamine; Pyrilamine; Receptors, Histamine | 1989 |
Neuronal histamine modulates feeding behavior through H1-receptor in rat hypothalamus.
Topics: Animals; Chlorpheniramine; Cimetidine; Drinking Behavior; Famotidine; Feeding Behavior; Histamine; Histamine H2 Antagonists; Hypothalamus; Injections, Intraventricular; Male; Motor Activity; Neurons; Promethazine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Reference Values; Thiazoles | 1989 |
Excitatory effect of histamine on the arousal system and its inhibition by H1 blockers.
Topics: Animals; Arousal; Brain Stem; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Histamine; Histamine H1 Antagonists; Injections, Intraventricular; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains; Thalamus | 1989 |
Mediators of the plasma extravasation response to silver nitrate in the rat skin, subplantar region and ankle joint.
Topics: Alprostadil; Animals; Bradykinin; Histamine; Indomethacin; Joints; Methysergide; Metiamide; Pyrilamine; Rats; Rats, Inbred Strains; Silver Nitrate; Skin | 1989 |
Histamine directly acts on beta-adrenoceptors as well as H1-histaminergic receptors, and causes positive inotropic effects in isolated ventricular muscles of carp heart (Cyprinus carpio).
Topics: Animals; Atropine; Carps; Cimetidine; Cyprinidae; Diphenhydramine; Electric Stimulation; Female; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Myocardial Contraction; Propranolol; Pyrilamine; Receptors, Adrenergic, beta; Receptors, Histamine H1; Stereoisomerism | 1989 |
Effects of isofloxythepin on central and peripheral histamine systems.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Central Nervous System; Dibenzothiepins; Edema; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Methylhistamines; Mice; Muscle Contraction; Muscle, Smooth; Peripheral Nerves; Potassium; Pyrilamine; Rats; Rats, Inbred Strains; Uterine Contraction | 1989 |
Effect of histamine H2-receptor antagonists on acute inflammatory of the rat paw oedema.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cimetidine; Edema; Freund's Adjuvant; Histamine; Histamine H2 Antagonists; Male; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Triazoles | 1989 |
Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain.
Topics: Animals; Brain; Brain Chemistry; Cyclic AMP; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; In Vitro Techniques; Male; Methylhistamines; Neurons; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H3 | 1989 |
Formation of ovarian follicular cysts and corpora lutea after treatment with antihistamine or indomethacin in prepubertal gilts.
Topics: Aging; Animals; Cimetidine; Female; Follicular Phase; Histamine; Histamine H1 Antagonists; Indomethacin; Luteal Phase; Ovarian Cysts; Ovulation; Prostaglandins; Pyrilamine; Swine | 1989 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine | 1989 |
Effects of histamine on thermosensitive neurons in rat preoptic slice preparations.
Topics: Animals; Body Temperature Regulation; Dose-Response Relationship, Drug; Electrophysiology; Famotidine; Female; Histamine; Histamine H2 Antagonists; Neurons; Preoptic Area; Pyrilamine; Rats; Rats, Inbred Strains; Temperature | 1989 |
HeLa cells have histamine H1-receptors which mediate activation of the K+ conductance.
Topics: Cell Membrane; Cimetidine; Electric Conductivity; Electric Stimulation; HeLa Cells; Histamine; Humans; Ion Channels; Membrane Potentials; Potassium; Pyrilamine; Quinine; Receptors, Histamine; Receptors, Histamine H1 | 1985 |
Effect of histamine and its antagonists on the course of Nippostrongylus brasiliensis in rats.
Topics: Animals; Histamine; Histamine Antagonists; Indomethacin; Male; Nematode Infections; Nippostrongylus; p-Methoxy-N-methylphenethylamine; Pyrilamine; Rats; Semicarbazides | 1989 |
Role of endogenous opioids and histamine in morphine induced emesis.
Topics: Animals; Cimetidine; Dogs; Endorphins; Histamine; Metiamide; Morphine; Naloxone; Pyrilamine; Vomiting | 1989 |
Expression of histamine H1 receptors on cultured histiocytic lymphoma cells.
Topics: Cycloheximide; Dactinomycin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Histamine; Humans; Lymphoma, Large B-Cell, Diffuse; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 1989 |
Role of histamine in traumatic brain edema. An experimental study in the rat.
Topics: Animals; Brain Edema; Brain Injuries; Cimetidine; Histamine; Male; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Wounds, Penetrating | 1989 |
Role of thromboxane A2, leukotriene C4 and histamine in the antigen-induced vasoconstriction in perfused, sensitized guinea-pig kidney.
Topics: Animals; Antigens; Guinea Pigs; Histamine; Immunization; In Vitro Techniques; Kidney; Ovalbumin; Perfusion; Pyrilamine; SRS-A; Thromboxane A2; Vasoconstriction | 1989 |
Histamine receptors in the smooth muscle of human internal mammary artery and saphenous vein.
Topics: Diuretics; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Indomethacin; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Pyridines; Pyrilamine; Receptors, Histamine; Saphenous Vein; Thoracic Arteries | 1989 |
Interactive effects of peptidoleukotrienes and histamine on microvascular permeability and their involvement in experimental cutaneous and conjunctival immediate hypersensitivity.
Topics: Animals; Capillary Permeability; Chromium Radioisotopes; Cimetidine; Conjunctiva; Dicarboxylic Acids; Guinea Pigs; Histamine; Hypersensitivity, Immediate; Iodine Radioisotopes; Leukotrienes; Male; Ovalbumin; Pyrilamine; Skin | 1989 |
Histamine-induced calcium transients in vascular smooth muscle cells: effects of verapamil and diltiazem.
Topics: Aminoquinolines; Animals; Aorta; Calcium; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient; Cimetidine; Cytosol; Diltiazem; Fluorescent Dyes; Histamine; Kinetics; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Pyrilamine; Rats; Rats, Inbred Strains; Sarcolemma; Swine; Verapamil | 1989 |
Effects of phorbol esters and forskolin on basal and histamine-induced accumulation of inositol phosphates in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Cimetidine; Colforsin; Epinephrine; Histamine; Inositol Phosphates; Kinetics; Norepinephrine; Phorbol Esters; Pyrilamine; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1989 |
Effects of histamine and serotonin on the contractility of isolated pregnant and nonpregnant human myometrium.
Topics: Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Female; Histamine; Humans; In Vitro Techniques; Ketanserin; Methysergide; Myometrium; Pregnancy; Pyrilamine; Serotonin; Uterine Contraction | 1989 |
Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells.
Topics: Acetylcholine; Animals; Atropine; Endothelium, Vascular; Female; Histamine; Male; Membrane Potentials; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Pyrilamine; Rats | 1989 |
Effect of histamine on human vas deferens in vitro.
Topics: Burimamide; Cimetidine; Culture Techniques; Dose-Response Relationship, Drug; Histamine; Humans; Male; Methylhistamines; Muscle Contraction; Pyrilamine; Vas Deferens | 1989 |
Histamine excites arcuate neurons in vitro through H1 receptors.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Cimetidine; Female; Histamine; In Vitro Techniques; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine | 1989 |
Evidence for both histamine H1 and H2 receptors on human articular chondrocytes.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamine; Humans; Prostaglandins E; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Tripelennamine | 1987 |
Effects of histamine on the guinea-pig stomach: excitation of smooth muscle and inhibition of transmitter release.
Topics: Animals; Atropine; Cimetidine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Membrane Potentials; Microelectrodes; Muscle, Smooth; Neuromuscular Junction; Pyrilamine; Stomach; Synaptic Transmission | 1987 |
Histamine-stimulated phosphoinositide hydrolysis in developing rat brain.
Topics: Aging; Animals; Cerebral Cortex; Histamine; Histamine Antagonists; Hydrolysis; Phenoxybenzamine; Phosphatidylinositols; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Regression Analysis | 1987 |
Inhibition of guinea pig ileum contractions mediated by a class of histamine receptor resembling the H3 subtype.
Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Histamine; Ileum; Imidazoles; Impromidine; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Pyrilamine; Receptors, Histamine; Receptors, Histamine H3 | 1987 |
Characterization of histamine H1-receptor on rat hepatocytes.
Topics: Animals; Cell Membrane; Cyclic AMP; Cyclic GMP; Histamine; In Vitro Techniques; Kinetics; Liver; Male; Peptide Hydrolases; Phospholipases A; Phospholipases A2; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1 | 1987 |
Stimulation of formation of inositol phosphates in primary cultures of bovine adrenal chromaffin cells by angiotensin II, histamine, bradykinin, and carbachol.
Topics: Adrenal Medulla; Angiotensin II; Animals; Bradykinin; Carbachol; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Dose-Response Relationship, Drug; Eledoisin; Histamine; Inositol Phosphates; Neurokinin A; Neuropeptides; Pyrilamine; Sugar Phosphates | 1988 |
Phosphoinositides and cicletanine.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Cells, Cultured; Dimaprit; Diuretics; Guinea Pigs; Histamine; Male; Muscle, Smooth, Vascular; Phenylephrine; Phosphatidylinositols; Pyridines; Pyrilamine; Thiourea | 1988 |
Angiotensin II potentiates prostaglandin stimulation of cyclic AMP levels in intact bovine adrenal medulla cells but not adenylate cyclase in permeabilized cells.
Topics: Adenylyl Cyclases; Adrenal Medulla; Alprostadil; Angiotensin II; Animals; Cattle; Cell Membrane Permeability; Cells, Cultured; Cyclic AMP; Histamine; Pyrilamine; Tetradecanoylphorbol Acetate | 1988 |
Histamine H1-receptors mediate phosphoinositide and calcium response in cultured smooth muscle cells--interaction with cicletanine (CIC).
Topics: Animals; Antihypertensive Agents; Calcium; Cells, Cultured; Diuretics; Guinea Pigs; Histamine; Male; Muscle, Smooth, Vascular; Phosphatidylinositols; Pyridines; Pyrilamine; Receptors, Histamine H1 | 1988 |
Predominance of histamine H1 receptors on liver plasma membrane.
Topics: Animals; Cell Membrane; Dihydroergotoxine; Dinoprostone; Histamine; Liver; Male; Prostaglandins E; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Histamine; Receptors, Histamine H1; Receptors, Prostaglandin; Receptors, Prostaglandin E | 1985 |
Nicotine is a competitive antagonist for H1-receptors in smooth muscles.
Topics: Animals; Aorta; Binding, Competitive; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Muscle, Smooth; Muscle, Smooth, Vascular; Nicotine; Norepinephrine; Pyrilamine; Rabbits; Trachea | 1985 |
Synergistic interaction between histamine and ouabain on ventricular fibrillation threshold.
Topics: Animals; Cimetidine; Coronary Circulation; Drug Synergism; Electrocardiography; Guinea Pigs; Heart Rate; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Pyrilamine; Ventricular Fibrillation | 1985 |
Regulation and actions of gastrointestinal somatostatin.
Topics: Animals; Calcium; Carbachol; Cimetidine; Colon; Egtazic Acid; Feedback; Gastric Mucosa; Gastrins; Histamine; Hydrogen-Ion Concentration; Intestine, Small; Lanthanum; Pimozide; Pyrilamine; Secretory Rate; Somatostatin; Trifluoperazine | 1985 |
Histamine H1-receptors in the guinea-pig urinary bladder.
Topics: Animals; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Male; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Urinary Bladder | 1985 |
Contraction induced by (-)-tartaric acid on rat isolated gastric fundus and its inhibition with indomethacin.
Topics: Acetylcholine; Animals; Atropine; Dinoprostone; Female; Gastric Fundus; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins E; Pyrilamine; Rats; Rats, Inbred Strains; Tartrates | 1985 |
A study of the H2-receptor for histamine stimulating adenylate cyclase in homogenates of guinea-pig lung parenchyma.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Colforsin; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Lung; Male; Propranolol; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2 | 1986 |
Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs.
Topics: Anesthetics, Local; Animals; Atropine; Chlorpheniramine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Lidocaine; Male; Procaine; Promethazine; Pyrilamine; Tachycardia | 1986 |
The effects of alpha 2 adrenoceptor agonists on airway pressure in anaesthetized sheep.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Airway Resistance; Animals; Clonidine; Dioxanes; Female; Histamine; Idazoxan; Injections, Intravenous; Injections, Intraventricular; Methoxamine; Prazosin; Pyrilamine; Sheep; Tripelennamine; Xylazine | 1986 |
Effects of SK&F 93944 (Temelastine), a potent histamine H1-receptor antagonist in pharmacologic and antigen-induced bronchoconstriction.
Topics: Animals; Antigens; Bronchi; Dogs; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Ovalbumin; Pyrilamine; Pyrimidinones; Trachea | 1986 |
Conjunctival eosinophil infiltration evoked by histamine and immediate hypersensitivity. Modification by H1- and H2-receptor blockade.
Topics: Animals; Cell Movement; Cimetidine; Conjunctival Diseases; Eosinophils; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypersensitivity, Immediate; Male; Pyrilamine | 1986 |
Histamine and histamine receptors: behavioral thermoregulation in the salamander Necturus maculosus.
Topics: Animals; Body Temperature Regulation; Cimetidine; Dimaprit; Histamine; Histidine; Necturus; Pyridines; Pyrilamine; Receptors, Histamine; Thiourea | 1986 |
Histaminergic stimulation of prolactin secretion mediated via H1- or H2-receptors: dependence on routes of administration.
Topics: Animals; Cimetidine; Dimaprit; Histamine; Histamine H1 Antagonists; Male; Methylhistamines; Pituitary Gland, Anterior; Prolactin; Pyrilamine; Pyrimidinones; Rats; Receptors, Histamine; Thiazoles; Thiourea | 1986 |
Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system.
Topics: Animals; Autonomic Nervous System; Central Nervous System; Cerebrovascular Circulation; Female; Guinea Pigs; Hemodynamics; Histamine; Histamine H1 Antagonists; Male; Parasympatholytics; Pyrilamine; Pyrimidinones; Skin Absorption; Sympathetic Nervous System | 1986 |
Adenosine antagonizes the histamine-induced stimulation of human atrial myocardium: protection by H1-receptor blockade.
Topics: Adenosine; Atrial Function; Heart; Heart Atria; Heart Rate; Histamine; Histamine H1 Antagonists; Humans; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1 | 1987 |
Role of endogenous histamine in postanaphylactic phase of allergic inflammation in rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Capillary Permeability; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; Hypersensitivity; Inflammation; Methysergide; Pyrilamine; Rats; Time Factors | 1987 |
Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists.
Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine H1 Antagonists; Humans; Prostaglandins E; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Synovial Membrane; Tripelennamine | 1987 |
Plasmodium berghei-infected mice: lack of effect of meclizine and cimetidine on the development of pulmonary oedema.
Topics: Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Malaria; Male; Meclizine; Mice; Plasmodium berghei; Pulmonary Edema; Pyrilamine | 1986 |
Histamine sensitive sites in hippocampus: their probable role on prolactin release in male rats.
Topics: Animals; Hippocampus; Histamine; Histamine H1 Antagonists; Male; Methylhistidines; Microinjections; Prolactin; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Stress, Physiological | 1987 |
[Arrhythmogenic effects of histamine on ischemic hearts of guinea pigs].
Topics: Animals; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Cricetinae; Female; Heart Rate; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Myocardial Infarction; Pyrilamine | 1987 |
Histamine-induced potentiation of cholinergic transmission in chick oesophagus (Gallus gallus).
Topics: Animals; Animals, Newborn; Chickens; Dimethylphenylpiperazinium Iodide; Esophagus; Histamine; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Pyrilamine; Receptors, Histamine H1; Stimulation, Chemical; Synaptic Transmission | 1988 |
Histamine H1-receptors mediate phosphoinositide hydrolysis in astrocyte-enriched primary cultures.
Topics: Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Histamine; Histamine H1 Antagonists; Inositol Phosphates; Phosphatidylinositols; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Time Factors | 1988 |
Mechanism of histamine-induced epinephrine release in guinea pig.
Topics: Animals; Bronchi; Cimetidine; Decerebrate State; Epinephrine; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Male; Pyrilamine; Sympathectomy, Chemical | 1988 |
Pressor response mediated via histamine H1-receptors of the guinea-pig sympathetic ganglia.
Topics: Animals; Atropine; Blood Pressure; Bretylium Tosylate; Dimethylphenylpiperazinium Iodide; Female; Ganglia, Sympathetic; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Histamine; Hydroxydopamines; Male; Metiamide; Nicotine; Oxidopamine; Pyrilamine; Receptors, Histamine H1; Reserpine | 1988 |
Studies on the site and mechanism of the inhibitory action of intracerebral histamine on the cold-stimulated thyrotropin secretion in male rats.
Topics: Animals; Brain Mapping; Cimetidine; Cold Temperature; Histamine; Hypothalamus; Imidazoles; Impromidine; Injections, Intraventricular; Male; Pyridines; Pyrilamine; Rats; Thyrotropin | 1985 |
The effects of histamine and some related compounds on conditioned avoidance response in rats.
Topics: Acetylcholine; Animals; Avoidance Learning; Dimaprit; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Hypothalamus; Injections, Intraventricular; Kinetics; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains; Scopolamine; Thiazoles; Thiourea | 1985 |
Conjunctival immediate hypersensitivity: re-evaluation of histamine involvement in the vasopermeability response.
Topics: Albumins; Animals; Capillary Permeability; Cimetidine; Conjunctiva; Dimaprit; Dose-Response Relationship, Drug; Drug Combinations; Eyelids; Guinea Pigs; Histamine; Histamine Antagonists; Hypersensitivity, Immediate; Imidazoles; Impromidine; Male; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1986 |
Metronidazole and 5-aminosalicylic acid enhance the contractile activity of histaminergic agonists on the guinea-pig isolated ileum.
Topics: Aminosalicylic Acids; Animals; Cimetidine; Computers; Dimaprit; Dose-Response Relationship, Drug; Drug Synergism; Duodenum; Female; Guinea Pigs; Heart; Histamine; Ileum; In Vitro Techniques; Jejunum; Male; Mesalamine; Metronidazole; Muscle Contraction; Myenteric Plexus; Pyrilamine; Receptors, Histamine; Scopolamine; Tetrodotoxin; Thiourea | 1986 |
Selective enhancement of histamine H1-receptor responses in guinea-pig ileal smooth muscle by 1,4-dithiothreitol.
Topics: Acetylcholine; Animals; Dimaprit; Dithionitrobenzoic Acid; Dithiothreitol; Dose-Response Relationship, Drug; Female; Guanidines; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Thiourea | 1986 |
Participation of vascular H1-receptors in histaminergic relaxation of rabbit middle cerebral artery in vitro.
Topics: Animals; Cerebral Arteries; Cimetidine; Dimaprit; Drug Interactions; Histamine; In Vitro Techniques; Methylhistamines; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Thiourea | 1986 |
Effect of histamine and its blockers on plasma beta-endorphin-like immunoreactivity in rats.
Topics: Animals; beta-Endorphin; Endorphins; Famotidine; Histamine; Hypothalamus; Male; Pituitary Gland; Pituitary Gland, Anterior; Pyrilamine; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hydroxyzine; Hypersensitivity, Immediate; Male; Mice; Mice, Inbred Strains; Pyrilamine; Rats; Rats, Inbred Strains; Skin; Species Specificity; Terfenadine | 1987 |
Characterization of histamine receptors in isolated rabbit veins.
Topics: Animals; Cimetidine; Endothelium, Vascular; Female; Histamine; Imidazoles; Impromidine; Male; Pyrilamine; Rabbits; Ranitidine; Receptors, Histamine; Receptors, Histamine H2; Species Specificity; Vasoconstriction; Veins | 1987 |
Endothelium-dependent relaxing effect of histamine on the isolated guinea-pig main pulmonary artery strips.
Topics: Animals; Cimetidine; Endothelium, Vascular; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Relaxation; Pulmonary Artery; Pyrilamine; Receptors, Histamine H2 | 1987 |
Evidence for histaminergic arousal mechanisms in the hypothalamus of cat.
Topics: Animals; Arousal; Cats; Dimaprit; Female; Histamine; Histamine Antagonists; Histidine Decarboxylase; Hypothalamus; Hypothalamus, Posterior; Injections; Injections, Intraperitoneal; Male; Methylhistidines; Pyrilamine; Thiourea | 1988 |
Role of central histaminergic mechanism in behavioural depression (swimming despair) in mice.
Topics: Animals; Atropine; Central Nervous System; Cimetidine; Depression; Desipramine; Disease Models, Animal; Histamine; Imidazoles; Imipramine; Impromidine; Male; Mice; Motor Activity; Pyrilamine; Receptors, Histamine H2 | 1988 |
A highly potent and selective H3 agonist relaxes rabbit middle cerebral artery, in vitro.
Topics: Animals; Cerebral Arteries; Cimetidine; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Methylhistamines; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Pyrilamine; Rabbits; Receptors, Histamine | 1988 |
Histamine-induced inositol phospholipid breakdown in the longitudinal smooth muscle of guinea-pig ileum.
Topics: Animals; Cerebellum; Cimetidine; Female; Guinea Pigs; Histamine; Ileum; Imidazoles; Impromidine; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Muscle Contraction; Phosphatidylinositols; Pyrilamine | 1985 |
Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; Inositol; Inositol Phosphates; Kinetics; Male; Metiamide; Norepinephrine; Prazosin; Propranolol; Pyrilamine; Serotonin; Sugar Phosphates; Tritium | 1985 |
Restraint stress stimulation of prolactin and ACTH secretion: role of brain histamine.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Histamine; Hypothalamo-Hypophyseal System; Male; Methylhistidines; Pituitary-Adrenal System; Prolactin; Pyrilamine; Ranitidine; Rats; Synaptic Transmission | 1986 |
H1 action of histamine on aldosterone and cortisol secretion by perfused dog adrenal.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Corticosterone; Dogs; Histamine; Hydrocortisone; In Vitro Techniques; Male; Methysergide; Metiamide; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1 | 1986 |
Phosphoinositide hydrolysis mediated by histamine H1-receptors in rat brain cortex.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Histamine; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Kinetics; Male; Phenoxybenzamine; Phosphatidylinositols; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1 | 1986 |
3H-mepyramine binding and histamine-stimulated cAMP accumulation in mammalian retina.
Topics: Aminopyridines; Animals; Brain; Cattle; Cyclic AMP; Dopamine; Guinea Pigs; Histamine; In Vitro Techniques; Pyrilamine; Rabbits; Receptors, Histamine; Retina; Tritium | 1986 |
Histamine in dorsal and ventral hippocampus. II. Effects of H1 and H2 histamine antagonists on exploratory behavior in male rats.
Topics: Aminopyridines; Animals; Brain Mapping; Exploratory Behavior; Hippocampus; Histamine; Histidine Decarboxylase; Male; Methylhistidines; Motor Activity; Neural Inhibition; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Synaptic Transmission | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Histamine receptor effects on dissipation of an intracellular proton gradient of isolated gastric mucosal surface cells.
Topics: Animals; Bicarbonates; Chlorides; Cimetidine; Dimaprit; Diphenhydramine; Gastric Acid; Gastric Mucosa; Histamine; Protons; Pyridines; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Sodium; Thiourea | 1987 |
Time course analyses of kinins and other mediators in plasma exudation of rat kaolin-induced pleurisy.
Topics: Animals; Bromelains; Captopril; Exudates and Transudates; Histamine; Immunoenzyme Techniques; Indomethacin; Kaolin; Kinins; Male; Methysergide; Pleurisy; Pyrilamine; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2; Time Factors | 1988 |
Effects of histamine and related compounds on thyrotropin secretion in rats.
Topics: Animals; Dose-Response Relationship, Drug; Famotidine; Histamine; Histidine; Male; Pyrilamine; Rats; Rats, Inbred Strains; Thiazoles; Thyrotropin; Thyrotropin-Releasing Hormone | 1986 |
Actions of nizatidine on the rat uterus, dog stomach and experimentally induced gastric lesions.
Topics: Animals; Aspirin; Atropine; Dogs; Duodenum; Female; Gastrointestinal Motility; Guanidines; Guinea Pigs; Histamine; Histamine Antagonists; Ligation; Nizatidine; Pyrilamine; Rats; Stomach; Stomach Ulcer; Thiazoles; Uterus | 1986 |
Analysis of tumor-promoter-induced inflammation in rats: participation of histamine and prostaglandin E2.
Topics: Animals; Capillary Permeability; Dinoprostone; Edema; Histamine; Indomethacin; Inflammation; Lyngbya Toxins; Methysergide; Neutrophils; Prostaglandins E; Pyrilamine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Effects of histamine and its blocker on thyrotropin releasing hormone release from rat adrenal gland in vitro.
Topics: Adrenal Glands; Animals; Famotidine; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Pyrilamine; Rats; Rats, Inbred Strains; Thiazoles; Thyrotropin-Releasing Hormone | 1987 |
Role of cyclooxygenase products of arachidonic acid metabolism in Ascaris antigen-induced bronchoconstriction in sensitized dogs.
Topics: Animals; Antigens, Helminth; Arachidonic Acids; Ascaris; Blood Pressure; Chromones; Dogs; Epoprostenol; Heart Rate; Histamine; Indomethacin; Lung; Lung Volume Measurements; Male; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiration; SRS-A | 1988 |
Long-term depletion of histamine in guinea-pigs by administration of alpha-fluoromethylhistidine, a specific inhibitor of histidine decarboxylase; effect on the sensitivity of histamine receptors.
Topics: Adenylyl Cyclases; Animals; Carboxy-Lyases; Dihydroxyphenylalanine; Guinea Pigs; Histamine; Histidine; Histidine Decarboxylase; In Vitro Techniques; Male; Methylhistidines; Muscle Contraction; Pyrilamine; Receptors, Histamine | 1988 |
Effect of H1 and H2 agonists on the chemiluminescence of human blood mononuclear cells induced by phytohaemagglutinin.
Topics: Cimetidine; Histamine; Humans; Imidazoles; Impromidine; Luminescent Measurements; Methylhistamines; Monocytes; Phytohemagglutinins; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Structure-Activity Relationship | 1985 |
Characteristics of canine lower esophageal sphincter: a new electrophysiological tool.
Topics: Animals; Carbachol; Cimetidine; Dogs; Electric Stimulation; Electrophysiology; Esophagus; Female; Histamine; In Vitro Techniques; Intercellular Junctions; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Pirenzepine; Pyrilamine; Reference Values; Tetrodotoxin | 1988 |
Inotropic effect of histamine on papillary muscle of guinea pig with right ventricular hypertrophy.
Topics: Animals; Cardiomyopathy, Hypertrophic; Cimetidine; Epinephrine; Female; Guinea Pigs; Histamine; Male; Myocardial Contraction; Papillary Muscles; Pyrilamine | 1988 |
Biphasic effects of intra-accumbens histamine administration on spontaneous motor activity in the rat; a role for central histamine receptors.
Topics: Animals; Histamine; Male; Methylhistamines; Motor Activity; Nucleus Accumbens; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Septal Nuclei; Thiazoles | 1988 |
Changes in the feeding behavior of rats elicited by histamine infusion.
Topics: Animals; Catheterization; Cimetidine; Circadian Rhythm; Dose-Response Relationship, Drug; Feeding Behavior; Histamine; Male; Pyrilamine; Rats; Rats, Inbred Strains; Suprachiasmatic Nucleus | 1988 |
Histamine and related substances influence neurotransmission in the semicircular canal.
Topics: Animals; Atropine; Hair Cells, Auditory; Histamine; Histamine Antagonists; Methylhistidines; Pyrilamine; Rana pipiens; Receptors, Cholinergic; Semicircular Canals; Vestibular Nerve | 1988 |
Regionally variable pulmonary artery responses to C3a.
Topics: Animals; Complement C3; Complement C3a; Female; Histamine; Male; Norepinephrine; Pulmonary Artery; Pyrilamine; Rabbits; Vasoconstriction | 1988 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
Histaminergic mediation of the stress-induced release of prolactin in male rats.
Topics: Animals; Cimetidine; Ether; Histamine; Injections, Intravenous; Injections, Intraventricular; Male; Prolactin; Pyrilamine; Pyrimidinones; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Restraint, Physical; Stress, Physiological | 1988 |
Characterization of functional histamine H1 receptors on a cultured smooth muscle cell line.
Topics: Actins; Animals; Calcium; Cell Line; Cricetinae; Deoxyribonucleases; Flow Cytometry; Histamine; Ligands; Male; Muscle Contraction; Muscle, Smooth; Polymers; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Software; Vas Deferens | 1988 |
Presynaptic inhibition produced by histamine at nicotinic synapses in enteric ganglia.
Topics: Acetylcholine; Action Potentials; Animals; Cimetidine; Evoked Potentials; Ganglia; Guinea Pigs; Hexamethonium Compounds; Histamine; Intestines; Pyrilamine; Synapses | 1988 |
The actions of histamine in cat and rabbit superior cervical ganglia.
Topics: Animals; Cats; Female; Ganglia, Sympathetic; Histamine; Male; Membrane Potentials; Pyrilamine; Rabbits; Receptors, Histamine H1 | 1988 |
Mast cell infiltration: a possible mechanism for vein graft vasospasm.
Topics: Animals; Carotid Arteries; Cimetidine; Dose-Response Relationship, Drug; Histamine; Isometric Contraction; Jugular Veins; Male; Mast Cells; Muscle, Smooth, Vascular; Pyrilamine; Rabbits | 1988 |
The actions of histamine on the separated layers of the guinea-pig uterus: the influence of ovarian steroids.
Topics: Animals; Dose-Response Relationship, Drug; Estrogens; Female; Guinea Pigs; Histamine; In Vitro Techniques; Progesterone; Pyrilamine; Uterine Contraction; Uterus | 1988 |
Histamine stimulation of prostaglandin and HETE synthesis in human endothelial cells.
Topics: Arachidonic Acids; Carbon Radioisotopes; Cells, Cultured; Endothelium, Vascular; Female; Gas Chromatography-Mass Spectrometry; Histamine; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Microsomes; Pregnancy; Prostaglandins; Pyrilamine; Umbilical Arteries; Umbilical Veins | 1988 |
Investigation of mechanism of fade of gastrin-stimulated gastric acid secretion in the cat.
Topics: Animals; Cats; Female; Gastric Acid; Gastrins; Histamine; Isoproterenol; Male; Methysergide; Phentolamine; Propranolol; Pyrilamine; Serotonin; Time Factors | 1988 |
The influence of histamine at various concentrations on the cell cycle state of hematopoietic stem cells (CFU-s).
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cimetidine; Colony-Forming Units Assay; Female; Hematopoietic Stem Cells; Histamine; Male; Mice; Mice, Inbred Strains; Pyrilamine | 1988 |
Histamine release by some new skeletal muscle relaxants studied at the rat ileum.
Topics: Animals; Atracurium; Dose-Response Relationship, Drug; Histamine; Ileum; Male; Muscle Contraction; Neuromuscular Blocking Agents; Osmolar Concentration; Pyrilamine; Rats; Rats, Inbred Strains | 1988 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Is there a prostaglandin involvement in the positive inotropic action of histamine in isolated pregnant rat uterus, apparently mediated via H1-receptors activation?
Topics: Alprostadil; Animals; Aspirin; Chlorpheniramine; Cimetidine; Dinoprost; Dinoprostone; Female; Histamine; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Pyrilamine; Quinacrine; Rats; Receptors, Histamine; Receptors, Histamine H1; Stimulation, Chemical; Uterine Contraction | 1987 |
Effect of cimetidine and pyrilamine on histamine-induced ocular surface hyperemia.
Topics: Aminopyridines; Animals; Cimetidine; Drug Therapy, Combination; Eye Diseases; Female; Histamine; Hyperemia; Pyrilamine; Rabbits | 1986 |
Suppression by muscarinic M2 stimulation of the contractile mechanism via histamine H1 receptors in the longitudinal muscle of guinea pig ileum.
Topics: Animals; Atropine; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Ileum; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Phentolamine; Pirenzepine; Propranolol; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Temperature; Tetrodotoxin | 1987 |
Pathogenesis of coronary artery spasm in miniature swine with regional intimal thickening after balloon denudation.
Topics: Animals; Atropine; Calcium; Coronary Vasospasm; Coronary Vessels; Disease Models, Animal; Endothelium; Guanethidine; Histamine; Pyrilamine; Swine; Tetrodotoxin | 1987 |
Alteration by histamine of the sympathetic nerve-mediated contractions in the bovine ovarian follicle wall in vitro.
Topics: Animals; Cattle; Cimetidine; Electrolytes; Female; Glucose; Histamine; In Vitro Techniques; Methylhistamines; Muscle Contraction; Norepinephrine; Ovary; Proteins; Pyrilamine; Sympathetic Nervous System | 1987 |
Mechanism of the central hyperglycemic action of histamine in mice.
Topics: Adrenalectomy; Animals; Blood Glucose; Chlorpheniramine; Chromatography, High Pressure Liquid; Corticosterone; Dose-Response Relationship, Drug; Epinephrine; Histamine; Hyperglycemia; Mice; Norepinephrine; Phentolamine; Promethazine; Propranolol; Pyrilamine; Pyrimethamine; Receptors, Histamine H1; Receptors, Histamine H2; Time Factors | 1987 |
Histamine-induced calcium release and phorbol antagonism in cultured airway smooth muscle cells.
Topics: Animals; Benzofurans; Calcium; Cells, Cultured; Cimetidine; Dogs; Dose-Response Relationship, Drug; Fura-2; Histamine; Mathematics; Muscle, Smooth; Nifedipine; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Type 1 hypersensitivity reactions in reconstructed tissues using syngeneic cell types.
Topics: Animals; Cells, Cultured; Electrophysiology; Epithelium; Guinea Pigs; Histamine; Hypersensitivity, Immediate; In Vitro Techniques; Kinins; Lactoglobulins; Mast Cells; Ovalbumin; Peritoneal Cavity; Pyrilamine; Rats; Rats, Inbred Strains; Tetrodotoxin | 1987 |
Histamine stimulates inositol phosphate accumulation via the H1-receptor in cultured human endothelial cells.
Topics: Cells, Cultured; Cimetidine; Endothelium, Vascular; Female; Histamine; Humans; Inositol; Inositol Phosphates; Kinetics; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sugar Phosphates; Umbilical Veins | 1987 |
The effect of inhaled leukotriene D4, histamine, or antigen on central and peripheral airways of guinea pigs: analysis of bronchograms with an interactive image analysis system.
Topics: Anaphylaxis; Animals; Antigens; Benzoquinones; Bronchi; Female; Guinea Pigs; Histamine; Male; Pyrilamine; Quinones; Respiratory Physiological Phenomena; Respiratory System; SRS-A | 1987 |
Vasoactive drugs, microvascular permeability, and hemorrhagic pancreatitis in cats.
Topics: Animals; Capillary Permeability; Cats; Cimetidine; Drug Synergism; Female; Hemorrhage; Histamine; Indomethacin; Male; Pancreatitis; Prostaglandins E, Synthetic; Pyrilamine | 1987 |
Mediators of C5a-induced bronchoconstriction in the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A | 1987 |
Histamine affects release and biosynthesis of opioid peptides primarily via H1-receptors in bovine chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Cimetidine; Clemastine; Cobalt; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Gallopamil; Histamine; Histamine Antagonists; Nifedipine; Protein Precursors; Pyrilamine; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; RNA, Messenger | 1987 |
Pulmonary gas trapping in the guinea pig and its application in pharmacological testing.
Topics: Administration, Inhalation; Aerosols; Animals; Atropine; Gases; Guinea Pigs; Histamine; Lung; Male; Methacholine Compounds; Pyrilamine; SRS-A | 1987 |
Regulation of membrane histamine H1-receptor binding sites by guanine nucleotides, mono- and divalent cations.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Cattle; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Histamine; In Vitro Techniques; Magnesium; Male; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sodium; Tritium | 1986 |
The interaction of ethanol with central histaminergic stimulation of the pituitary-adrenocortical and hyperlipemic activity.
Topics: Animals; Brain; Cimetidine; Corticosterone; Ethanol; Fatty Acids, Nonesterified; Histamine; Male; Pituitary-Adrenal System; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine | 1986 |
Relationships between cardiac hyperactivity, oxygen tension, and release of vasodilator material in coronary autoregulation of guinea-pig hearts.
Topics: Adenosine; Animals; Burimamide; Female; Guinea Pigs; Heart; Heart Rate; Histamine; Homeostasis; Male; Myocardial Contraction; Oxygen; Partial Pressure; Pyrilamine; Vasodilation | 1986 |
Histamine-induced hydrolysis of polyphosphoinositides in guinea-pig ileum and brain.
Topics: Animals; Brain Chemistry; Female; Guinea Pigs; Histamine; Hydrolysis; Ileum; In Vitro Techniques; Inositol Phosphates; Male; Muscle, Smooth; Pyrilamine; Stimulation, Chemical; Sugar Phosphates; Time Factors | 1986 |
Effect of centrally administered histamine on body temperature in guinea pigs.
Topics: Animals; Body Temperature; Cerebral Ventricles; Female; Guinea Pigs; Histamine; Injections, Intraventricular; Male; Pyrilamine | 1986 |
Inhibition of complement dependent experimental inflammation in human skin by different heparin fractions.
Topics: Animals; Complement Inactivator Proteins; Heparin; Histamine; Humans; Inflammation; Kinetics; Pyrilamine; Skin; Structure-Activity Relationship; Swine; Trypsin | 1986 |
Effect of histamine on delayed-type hypersensitivity in mice.
Topics: Adrenalectomy; Animals; Chemotaxis; Cimetidine; Female; Histamine; Hypersensitivity, Delayed; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Pyrilamine | 1986 |
Histamine induces ovulation in the isolated perfused rat ovary.
Topics: Animals; Cimetidine; Female; Gonadotropins, Equine; Histamine; Luteinizing Hormone; Ovary; Ovulation Induction; Perfusion; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains | 1986 |
Histamine-induced microvascular permeability increases in hamster skin: a response predominantly mediated by H2-receptors.
Topics: Animals; Capillary Permeability; Cimetidine; Cricetinae; Dose-Response Relationship, Drug; Female; Histamine; Kinetics; Male; Mesocricetus; Pyrilamine; Receptors, Histamine H2; Skin | 1986 |
Injectable aspirin and mepyramine abolish post-ischaemic hyperalgesia in rats.
Topics: Aminopyridines; Animals; Aspirin; Histamine; Hyperalgesia; Hyperesthesia; Ischemia; Male; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains | 1986 |
Effects of opioid peptides and morphine on histamine-induced catecholamine secretion from cultured, bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Endorphins; Epinephrine; Histamine; Morphine; Norepinephrine; Pyrilamine | 1986 |
Increase in plasma catecholamines by intraventricular injection of histamine in conscious rats.
Topics: Animals; Brain; Epinephrine; Histamine; Injections, Intraventricular; Male; Norepinephrine; Pyrilamine; Ranitidine; Rats | 1986 |
Regional variation in the characteristics of histamine H1-agonist mediated breakdown of inositol phospholipids in guinea-pig brain.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cerebellum; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Lithium; Male; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sugar Phosphates | 1986 |
Differential effect of temperature on histamine- and carbachol-stimulated inositol phospholipid breakdown in slices of guinea-pig cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Male; N-Methylscopolamine; Pyrilamine; Scopolamine Derivatives; Sugar Phosphates; Temperature | 1987 |
Microvascular effects of anaphylatoxins C3a and C5a.
Topics: Animals; Arterioles; Cheek; Complement C3; Complement C3a; Complement C5; Complement C5a; Cricetinae; Histamine; Humans; Male; Mesocricetus; Microcirculation; Oligopeptides; Platelet Aggregation; Pyrilamine; Vasoconstriction; Venules | 1985 |
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Blood Pressure; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A; Timolol; Vagotomy | 1985 |
Pharmacological characterization of opossum distal colonic muscularis mucosae in vitro.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Atropine; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Female; Histamine; In Vitro Techniques; Indomethacin; Lidocaine; Male; Muscle Contraction; Muscles; Norepinephrine; Opossums; Phentolamine; Propranolol; Pyrilamine; Tetrodotoxin | 1986 |
Histaminergic regulation of prolactin secretion: dose-response relationship and possible involvement of the dopaminergic system.
Topics: Adult; Cimetidine; Dose-Response Relationship, Drug; Histamine; Humans; Male; Metoclopramide; Prolactin; Pyrilamine; Receptors, Dopamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1986 |
Binding of 4(5)-[2-(4-azido-2-nitroanilino)ethyl]imidazole to histamine receptors in guinea pig cerebral cortical membranes.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Cimetidine; Guinea Pigs; Histamine; Kinetics; Male; Membranes; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Substrate Specificity; Vas Deferens | 1986 |
Histamine activates H1-receptors to induce cytosolic free calcium transients in cultured vascular smooth muscle cells from rat aorta.
Topics: Aminoquinolines; Animals; Calcium; Cells, Cultured; Cimetidine; Cytosol; Dose-Response Relationship, Drug; Histamine; Kinetics; Muscle, Smooth, Vascular; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1 | 1986 |
Pharmacological characterization of histamine receptors in the rabbit renal artery.
Topics: Animals; Endothelium; Histamine; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle, Smooth, Vascular; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Renal Artery | 1986 |
H1-histaminergic activation stimulates inositol-1-phosphate accumulation in chromaffin cells.
Topics: Adrenal Medulla; Animals; Bradykinin; Carbachol; Cattle; Cimetidine; Clemastine; Histamine; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sugar Phosphates; Time Factors | 1986 |
A simple technique to simultaneously assess activity at histamine H1- and H2-receptors in vivo.
Topics: Animals; Betahistine; Bronchi; Cimetidine; Female; Guinea Pigs; Heart Rate; Histamine; Male; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1985 |
N-ethylmaleimide-induced changes in agonist affinity for histamine H1-receptors in the guinea pig brain.
Topics: Animals; Cerebellum; Ethylmaleimide; Guinea Pigs; Histamine; In Vitro Techniques; Male; Membranes; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Sulfhydryl Reagents | 1985 |
A study of the effect of 8-aminoquinolines (primaquine, pamaquine, pentaquine) on the guinea-pig isolated ileum.
Topics: Aminoquinolines; Animals; Antimalarials; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Primaquine; Pyrilamine; Tachyphylaxis | 1985 |
Regional variation in the sensitivity of longitudinal smooth muscle to histamine at H1-receptors in guinea-pig ileum and colon.
Topics: Animals; Colon; Electric Stimulation; Female; Guinea Pigs; Histamine; Ileum; Male; Muscle Contraction; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Scopolamine; Tetrodotoxin; Tissue Distribution | 1985 |
Evidence for the involvement of histamine in the regulation of blood-brain barrier permeability.
Topics: Animals; Blood-Brain Barrier; Colforsin; Diterpenes; Dogs; Female; Fluorescein; Fluoresceins; Histamine; Histamine Antagonists; Male; Methylhistamines; Metiamide; Pyrilamine; Time Factors | 1985 |
Examination of the bronchoconstrictor response of guinea-pig isolated lung to beta-phenylethylamine.
Topics: Animals; Atropine; Bronchi; Carbachol; Dopamine; Drug Interactions; Female; Guinea Pigs; Histamine; Lung; Male; Methysergide; Metiamide; Muscle Contraction; Norepinephrine; Phenethylamines; Phentolamine; Propranolol; Pyrilamine; Serotonin | 1985 |
Evidence that tamoxifen is a histamine antagonist.
Topics: Acetylcholine; Animals; Dogs; Female; Histamine; Histamine Antagonists; Hydroxyzine; Male; Muscle Contraction; Phosphatidylethanolamines; Potassium; Pyrilamine; Serotonin; Tamoxifen; Trachea | 1985 |
Intravenous histamine reduces bombesin-stimulated gastrin release in dogs.
Topics: Animals; Bombesin; Cimetidine; Dogs; Gastric Juice; Gastrins; Histamine; Infusions, Parenteral; Pyrilamine | 1985 |
Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromones; Dexamethasone; Histamine; Indomethacin; Inflammation; Kinetics; Male; Methysergide; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A | 1985 |
Effect of Rumex nepalensis extracts on histamine, acetylcholine and carbachol evoked responses on isolated guinea pig ileum, frog rectus abdominis muscle, rabbit heart and blood pressure of dog.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Carbachol; Dogs; Guinea Pigs; Hemodynamics; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Plant Extracts; Pyrilamine; Rabbits; Succinylcholine | 1985 |
Involvement of histamine in vascular permeability increase of the rat pleurisy induced by phorbol myristate acetate.
Topics: Animals; Capillary Permeability; Cimetidine; Croton Oil; Drug Interactions; Histamine; Histamine Antagonists; Leukocytes; Male; Methysergide; Phorbols; Pleurisy; Pyrilamine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Histamine receptor activation by unsaturated (allyl and propargyl) homologs of histamine.
Topics: Adrenergic Fibers; Animals; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Muscle Contraction; Myocardial Contraction; Propranolol; Pyrilamine; Receptors, Histamine | 1985 |
Anti-inflammatory effect of intraventricularly administered histamine in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Female; Histamine; Inflammation; Injections, Intraventricular; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains | 1985 |
Analysis of the effects on body temperature of intracerebroventricular injection in anaesthetized dogs of gamma-aminobutyric acid.
Topics: Acetylcholine; Aminobutyrates; Animals; Body Temperature; Cerebral Ventricles; Dogs; Epinephrine; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Histamine; Injections; Isoproterenol; Lysergic Acid Diethylamide; Male; Morphine; Norepinephrine; Pentobarbital; Perfusion; Phenoxybenzamine; Phentolamine; Propranolol; Prostaglandins; Pyrilamine; Reserpine; Salicylates; Scopolamine; Serotonin; Time Factors | 1974 |
Actions of putative transmitters in the chicken vagus nerve/oesophagus and Remak nerve/rectum preparations.
Topics: Adenosine; Adenosine Diphosphate; Animals; Animals, Newborn; Chickens; Cyclic AMP; Electric Stimulation; Esophagus; Histamine; In Vitro Techniques; Indomethacin; Methysergide; Muscle Contraction; Neural Conduction; Neurotransmitter Agents; Norepinephrine; Phentolamine; Polyphloretin Phosphate; Propranolol; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Rectum; Scopolamine; Serotonin; Synaptic Transmission; Vagus Nerve | 1974 |
Proceedings: Vascular histamine receptors in the cat.
Topics: Animals; Blood Pressure; Blood Vessels; Cats; Depression, Chemical; Hindlimb; Histamine; Histamine H1 Antagonists; Metiamide; Perfusion; Pyrilamine; Receptors, Drug; Vasodilator Agents | 1974 |
Proceedings: Regulation of the cyclic AMP concentration in chick brain by beta-adrenoreceptors and histamine H2 receptors.
Topics: Animals; Animals, Newborn; Brain; Chickens; Cyclic AMP; Histamine; Isoproterenol; Pyrilamine; Receptors, Adrenergic; Receptors, Drug; Stimulation, Chemical | 1974 |
The effects of some prostaglandins on respiration in anaesthetized cats.
Topics: Animals; Atropine; Blood Gas Analysis; Blood Pressure; Carotid Arteries; Carotid Sinus; Cats; Cyanides; Denervation; Female; Histamine; Isoproterenol; Male; Propranolol; Prostaglandins; Pulmonary Circulation; Pyrilamine; Regional Blood Flow; Respiration; Vagotomy | 1974 |
The immunological release of slow-reacting substance of anaphylaxis from bovine lung.
Topics: Animals; Ascaris; Aspirin; Atropine; Cattle; Filtration; Guinea Pigs; Histamine; Horses; Ileum; In Vitro Techniques; Lung; Male; Methysergide; Muscle Contraction; Polyphloretin Phosphate; Prostaglandins; Pulmonary Veins; Pyrilamine; Serotonin; SRS-A | 1974 |
Effects of histamine agonists and antagonists on luminol-dependent chemiluminescence of granulocytes.
Topics: Cimetidine; Dimaprit; Granulocytes; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; Pyridazines; Pyridines; Pyrilamine; Ranitidine; Thiourea | 1984 |
Effects of histamine on human isolated heart muscle: comparison with effects of noradrenaline.
Topics: Cimetidine; Dimaprit; Heart; Histamine; Humans; In Vitro Techniques; Myocardial Contraction; Norepinephrine; Propranolol; Pyrilamine; Receptors, Histamine H2; Thiourea | 1980 |
Evidence for a direct anti-inflammatory action of calcitonin: inhibition of histamine-induced mouse pinnal oedema by porcine calcitonin.
Topics: Animals; Anti-Inflammatory Agents; Calcitonin; Calcium; Ear Diseases; Edema; Histamine; Histamine H1 Antagonists; Methysergide; Mice; Pyrilamine; Swine | 1980 |
Evaluation of the role of Histamine H1- and H2-receptors in cutaneous inflammation in the guinea-pig produced by histamine and mast cell degranulation.
Topics: Animals; Cimetidine; Dimaprit; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Inflammation; Male; Mast Cells; Mathematics; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Skin; Thiourea; Vasodilation | 1980 |
Effects of histamine receptor antagonists on alkali secretion by lleum.
Topics: Alkalies; Animals; Cimetidine; Histamine; Histamine H1 Antagonists; Ileum; Intestinal Secretions; Pyrilamine; Rabbits; Time Factors | 1981 |
The distribution of histamine H1-receptors in the rat brain: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Histamine; Histamine H2 Antagonists; Male; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1 | 1981 |
Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog.
Topics: Anesthesia; Animals; Blood Pressure; Cimetidine; Dogs; Dose-Response Relationship, Drug; Female; Furans; Gastric Acid; Guanidines; Histamine; Histamine H2 Antagonists; Male; Pyrilamine; Ranitidine | 1981 |
The effect of ranitidine on gastric acid secretory response curves to histamine, pentagastrin or bethanechol in the dog with a Heidenhain pouch.
Topics: Animals; Bethanechol Compounds; Cimetidine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Furans; Gastric Acid; Histamine; Histamine H2 Antagonists; Male; Pentagastrin; Pyrilamine; Ranitidine | 1981 |
The involvement of histamine receptor subtypes in gastric acid secretion and mucosal blood flow in the anaesthetized rabbit.
Topics: Animals; Blood Pressure; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Male; Pyrilamine; Rabbits; Receptors, Histamine; Regional Blood Flow; Secretory Rate | 1981 |
Characterization of [3H]mepyramine binding to the longitudinal muscle of guinea pig small intestine.
Topics: Aminopyridines; Animals; Binding Sites; Calcium; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hydrogen-Ion Concentration; In Vitro Techniques; Intestine, Small; Magnesium; Male; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1 | 1981 |
Regulative action of cyclic AMP and histamine on the immune response mediated by surface receptors of cells.
Topics: Animals; B-Lymphocytes; Cyclic AMP; Histamine; Histamine H2 Antagonists; Lymphocyte Activation; Lymphocytes; Metiamide; Mice; Mice, Inbred C57BL; Pyrilamine; Rosette Formation; T-Lymphocytes; T-Lymphocytes, Regulatory | 1981 |
Brain histamine H1- and H2-receptors and histamine-sensitive adenylate cyclase: effects of antipsychotics and antidepressants.
Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Antipsychotic Agents; Brain; Cimetidine; Female; Guinea Pigs; Histamine; Male; Pyrilamine; Radioligand Assay; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1981 |
Effect of H1-and H2-receptor antagonists on cutaneous inflammation evoked by histamine analogues and UV radiation.
Topics: Animals; Body Temperature; Cimetidine; Dermatitis; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Pyrilamine; Skin; Ultraviolet Rays; Vasodilation | 1982 |
An inhibitory effect of histamine on the rat anococcygeus muscle.
Topics: Acetylcholine; Animals; Carbachol; Cimetidine; Dimaprit; Drug Interactions; Guanidines; Histamine; Imidazoles; Impromidine; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Pyrilamine; Rats; Thiourea | 1982 |
Carrageenan-induced oedema in the rat paw - histamine participation.
Topics: Animals; Carrageenan; Cimetidine; Edema; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; p-Methoxy-N-methylphenethylamine; Plethysmography; Pyrilamine; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Histamine receptor agonists and antagonists on granulocyte adherence.
Topics: Cimetidine; Clonidine; Granulocytes; Histamine; Histamine Antagonists; Humans; Pyrilamine | 1982 |
The effect of histamine stimulation and H2 -receptor inhibition on the pituitary prolactin and ACTH release and on cortisol secretion in human males.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Furans; Histamine; Histamine H2 Antagonists; Humans; Hydrocortisone; Male; Middle Aged; Pituitary Gland, Anterior; Prolactin; Pyrilamine; Ranitidine | 1983 |
Evidence for histamine H1 and H2 receptors in guinea-pig oxyntic cells.
Topics: Animals; Carbonic Anhydrases; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Imidazoles; Impromidine; In Vitro Techniques; Methylhistamines; Parietal Cells, Gastric; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1983 |
Effects of histamine, H1- and H2-receptor antagonists on the activity of serotonergic neurons in the dorsal raphe nucleus.
Topics: Animals; Brain Stem; Cimetidine; Diphenhydramine; gamma-Aminobutyric Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Metiamide; Neurons; Pyrilamine; Ranitidine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin; Synaptic Transmission | 1983 |
Release of prolactin and luteinizing hormone by histamine agonists in ovariectomized, steroid-treated rats under ether anesthesia.
Topics: Animals; Castration; Dimaprit; Female; Histamine; Histamine H1 Antagonists; Luteinizing Hormone; Methylhistamines; Metiamide; Pituitary Gland, Anterior; Prolactin; Pyridines; Pyrilamine; Rats; Thiourea | 1983 |
The mechanism of the histamine-induced desensitization of guinea-pig ileum.
Topics: Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Male; Methylhistamines; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1 | 1984 |
The effect of histamine, H1 and H2 agonists, and H1 and H2 antagonists on postprandial pancreatic polypeptide release in dogs.
Topics: Animals; Cimetidine; Dimaprit; Dogs; Food; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Pancreatic Polypeptide; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Secretory Rate; Thiazoles; Thiourea | 1983 |
Relaxation and contraction responses to histamine in the human lung parenchymal strip.
Topics: Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; In Vitro Techniques; Indomethacin; Lung; Metiamide; Muscle Contraction; Muscle Relaxation; Potassium Chloride; Pyrilamine | 1984 |
Evidence for the existence of histamine H1- and H2-receptors on astrocytes of cultured rat central nervous system.
Topics: Aminopyridines; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cimetidine; Histamine; Histamine H1 Antagonists; Membrane Potentials; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Spinal Cord; Thiazoles | 1984 |
Intracellular study of effects of histamine on electrical behaviour of myenteric neurones in guinea-pig small intestine.
Topics: Action Potentials; Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Intestine, Small; Membrane Potentials; Myenteric Plexus; Neurons; Neurotransmitter Agents; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Serotonin; Thiourea | 1984 |
Excitatory and inhibitory effects of H1-blockers on isolated bullfrog spinal cords.
Topics: Animals; Diphenhydramine; Gallopamil; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Motor Neurons; Neuromuscular Depolarizing Agents; Pyrilamine; Rana catesbeiana; Spinal Cord; Tetrodotoxin | 1984 |
Effect of some drugs on the skin response of tick-resistant cattle to an allergenic extract of larval Rhipicephalus appendiculatus.
Topics: Animals; Aspirin; Cattle; Cattle Diseases; Cyclophosphamide; Histamine; Histamine H1 Antagonists; Hypersensitivity, Immediate; Intradermal Tests; Larva; Levamisole; Male; Phenylbutazone; Pyrilamine; Skin; Tick Infestations; Ticks | 1984 |
3H-Glycogen hydrolysis elicited by histamine in mouse brain slices: selective involvement of H1 receptors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Calcium; Glycogen; Histamine; Hydrolysis; In Vitro Techniques; Kinetics; Male; Mice; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1 | 1980 |
Effect of histamine on cyclic AMP levels in the submandibular gland.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Female; Guinea Pigs; Histamine; Methylhistamines; Metiamide; Pyrilamine; Submandibular Gland | 1981 |
Amylase secretion induced by histamine from guinea-pig parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; Amylases; Animals; Atropine; Guinea Pigs; Histamine; In Vitro Techniques; Male; Methylhistamines; Metiamide; Parotid Gland; Propranolol; Pyrilamine; Stimulation, Chemical; Time Factors | 1982 |
Histamine stimulation of digestive enzyme secretion by in vitro rabbit pancreas.
Topics: Amylases; Animals; Chymotrypsinogen; Cimetidine; Drug Combinations; Histamine; Histamine Antagonists; In Vitro Techniques; Lipase; Pancreas; Pancreatin; Pyrilamine; Rabbits; Stimulation, Chemical; Trypsinogen | 1982 |
Characterization of the enhanced paw edema response to carrageenan and dextran in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats.
Topics: Animals; Bradykinin; Carrageenan; Cyproheptadine; Dextrans; Dinoprostone; Dioxins; Drug Interactions; Edema; Histamine; Indomethacin; Male; p-Methoxy-N-methylphenethylamine; Polychlorinated Dibenzodioxins; Prostaglandins E; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin | 1984 |
The effect of histamine on microvascular permeability in the muscularis externa of rat small intestine.
Topics: Animals; Capillary Permeability; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Imidazoles; Impromidine; Intestine, Small; Male; Microscopy, Fluorescence; Muscle, Smooth; Pyrilamine; Rats; Rats, Inbred Strains | 1983 |
Inhibition of the TSH secretion by histamine in male rats.
Topics: Animals; Cimetidine; Cold Temperature; Histamine; Histamine Antagonists; Histidine; Imidazoles; Impromidine; Male; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thyrotropin; Thyrotropin-Releasing Hormone | 1983 |
Central histaminergic stimulation of pituitary--adrenocortical response in the rat.
Topics: Animals; Cimetidine; Corticosterone; Dimaprit; Dose-Response Relationship, Drug; Histamine; Imidazoles; Impromidine; Male; Pituitary-Adrenal System; Pyridines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1983 |
Studies on cutaneous vascular permeability in the rat: increases caused by histamine and histamine-like agents.
Topics: Animals; Capillary Permeability; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Histamine; Microcirculation; Pyrilamine; Rats; Regional Blood Flow; Skin; Thiourea | 1984 |
Studies on the effect of histamine in isolated human pulmonary arteries and veins.
Topics: Aged; Dimaprit; Female; Histamine; Humans; In Vitro Techniques; Male; Methylhistamines; Middle Aged; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phentolamine; Potassium; Pulmonary Artery; Pulmonary Veins; Pyrilamine; Thiourea | 1984 |
Histamine action on guinea pig ileal mucosa.
Topics: Animals; Bicarbonates; Biological Transport, Active; Chlorides; Dimaprit; Electric Conductivity; Female; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1984 |
[Imidazolic H2-agonists: importance of 2-amino substitution for pharmacological activity].
Topics: Animals; Biological Assay; Cats; Dimaprit; Gastric Acid; Guinea Pigs; Histamine; Methylhistamines; Muscle Relaxation; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Structure-Activity Relationship; Thiourea; Urinary Bladder | 1984 |
Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine.
Topics: Animals; Anticonvulsants; Autonomic Nervous System; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Dioxanes; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hypnotics and Sedatives; Lethal Dose 50; Loratadine; Male; Mice; Physostigmine; Piperidines; Pyrilamine; Rats; Saimiri; Time Factors | 1984 |
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder.
Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Scopolamine; Tetrodotoxin; Urinary Bladder | 1984 |
Effect of histamine on adenosine 3',5'-cyclic monophosphate levels in granulation tissue.
Topics: Animals; Burimamide; Cyclic AMP; Drug Interactions; Epinephrine; Formaldehyde; Granulation Tissue; Histamine; In Vitro Techniques; Male; Methylhistamines; Propranolol; Pyrilamine; Rats | 1980 |
Innervation of airway smooth muscle in the baboon: evidence for a nonadrenergic inhibitory system.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Haplorhini; Histamine; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Norepinephrine; Papio; Pyrilamine; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Trachea | 1980 |
Specific receptors for prostaglandins in airways.
Topics: Animals; Aspirin; Atropine; Bronchi; Cats; Epoprostenol; Female; Guinea Pigs; Histamine; Humans; Indomethacin; Isoproterenol; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Phentolamine; Propranolol; Prostaglandins E; Prostaglandins F; Pyrilamine; Receptors, Cell Surface; Receptors, Prostaglandin; Trachea | 1980 |
Histamine and human parathyroid adenoma: effect on adenosine 3',5'-monophosphate accumulation in vitro.
Topics: Adenoma; Cimetidine; Cyclic AMP; Female; Histamine; Humans; In Vitro Techniques; Isoproterenol; Male; Parathyroid Hormone; Parathyroid Neoplasms; Propranolol; Pyrilamine | 1981 |
Histamine H1-agonist potentiation of adenosine-stimulated cyclic AMP accumulation in slices of guinea-pig cerebral cortex: comparison of response and binding parameters.
Topics: Adenosine; Animals; Brain; Cyclic AMP; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Promethazine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1982 |
The effect of synthetic leukotrienes on tracheal microvascular permeability.
Topics: Animals; Capillary Permeability; Female; Guinea Pigs; Histamine; Indomethacin; Leukotriene E4; Male; Methacholine Chloride; Methacholine Compounds; Pyrilamine; SRS-A; Trachea | 1983 |
Specific allergen induces contraction of bronchi and formation of leukotrienes C4, D4, and E4 in human asthmatic lung.
Topics: Allergens; Asthma; Bronchi; Calcimycin; Histamine; Humans; In Vitro Techniques; Leukotriene E4; Lung; Muscle Contraction; Pyrilamine; SRS-A; Structure-Activity Relationship | 1983 |
Histamine-induced prolactin release: pharmacological characterization of receptors in male rats.
Topics: Anesthesia; Animals; Furans; Histamine; Male; Methylhistamines; Metiamide; Prolactin; Pyrilamine; Ranitidine; Rats; Receptors, Histamine | 1983 |
Investigation of leukotriene involvement in the vasopermeability response associated with guinea pig tracheal anaphylaxis: comparison with cutaneous anaphylaxis.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromium Radioisotopes; Chromones; Female; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene E4; Ovalbumin; Passive Cutaneous Anaphylaxis; Pyrilamine; SRS-A; Time Factors; Trachea | 1983 |
Chick retinal pigment epithelium. A new culture system for studying H2-histamine receptors.
Topics: Animals; Cells, Cultured; Chick Embryo; Cimetidine; Cyclic AMP; Diphenhydramine; Histamine; Methods; Pigment Epithelium of Eye; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2 | 1983 |
Studies with specific agonists and antagonists of the role of histamine H1- and H2-receptor activation in the pathogenesis of gastric lesions in rats.
Topics: Aminopyridines; Animals; Atropine; Dimaprit; Drug Interactions; Female; Histamine; Pyridines; Pyrilamine; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach Ulcer; Thiourea | 1984 |
Histamine stimulation of inositol 1-phosphate accumulation in lithium-treated slices from regions of guinea pig brain.
Topics: Animals; Brain; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Inositol; Inositol Phosphates; Lithium; Male; Pyrilamine; Receptors, Histamine H1; Time Factors | 1984 |
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemolysis; Histamine; Indomethacin; Male; Muscle Contraction; Norepinephrine; Peptides; Pyrilamine; Tachyphylaxis | 1984 |
Effects of human anaphylatoxins on guinea pig atria.
Topics: Alprostadil; Anaphylatoxins; Animals; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Guinea Pigs; Heart Rate; Histamine; Humans; In Vitro Techniques; Indomethacin; Myocardial Contraction; Peptides; Prostaglandins E; Pyrilamine | 1984 |
Catabolism of histamine in the isolated glomeruli and tubules of the rat kidney.
Topics: Amine Oxidase (Copper-Containing); Amodiaquine; Animals; Chromatography, Thin Layer; Guanidines; Histamine; Imidazoles; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains | 1983 |
Histamine-induced paradoxical growth hormone response to thyrotropin-releasing hormone in normal men.
Topics: Adult; Cimetidine; Growth Hormone; Histamine; Humans; Infusions, Parenteral; Male; Pyrilamine; Thyrotropin; Thyrotropin-Releasing Hormone | 1984 |
Modulation of basal and LRH-stimulated gonadotrophin secretion by histamine in normal men.
Topics: Animals; Cimetidine; Drug Interactions; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Histamine; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Pyrilamine | 1984 |
Direct and indirect actions of histamine on airway smooth muscle in guinea pigs.
Topics: Airway Resistance; Animals; Aspirin; Atropine; Carotid Sinus; Cromolyn Sodium; Diazoxide; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Muscle, Smooth; Pyrilamine; Serotonin; Tartrazine; Vagotomy | 1984 |
Production and antagonism of cutaneous vascular permeability in the guinea pig in response to histamine, leukotrienes and A23187.
Topics: Animals; Bradykinin; Calcimycin; Capillary Permeability; Chromones; Guinea Pigs; Histamine; Indomethacin; Injections, Intradermal; Male; Pyrilamine; Receptors, Histamine; Skin; SRS-A | 1984 |
The regulatory effect of histamine on the immune response: characterization of the cells involved.
Topics: Adult; Concanavalin A; Histamine; Histamine Antagonists; Humans; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Metiamide; Pyrilamine; T-Lymphocytes, Regulatory | 1980 |
Comparison of the agonist activity of impromidine (SK & F 92676) in anaesthetized rabbits and on the rabbit isolated fundic mucosa.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Acid; Gastric Fundus; Gastric Mucosa; Guanidines; Histamine; Imidazoles; Impromidine; Male; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H2 | 1981 |
Further experiments on the pharmacological actions of ergometrine.
Topics: Animals; Cattle; Cimetidine; Coronary Vessels; Dimaprit; Ergonovine; Gastric Acid; Guinea Pigs; Histamine; Muscle Contraction; Pyrilamine; Rats; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea | 1981 |
The role of histamine and serotonin in the inflammatory reaction in an experimental model of open wounds in the rat.
Topics: Animals; Capillary Permeability; Cimetidine; Granulation Tissue; Histamine; Histamine Antagonists; Inflammation; Male; Methysergide; Pyrilamine; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin Antagonists; Serum Albumin; Wound Healing | 1984 |
[Influence of carnosine on the immunosuppressive effect of histamine].
Topics: Animals; Carnosine; Dipeptides; Histamine; Immune Tolerance; Immunosuppressive Agents; Lymphocytes; Metiamide; Mice; Mice, Inbred C57BL; Pyrilamine; Receptors, Histamine H2 | 1984 |
Effects of histamine antagonists on noradrenaline-stimulated blood flow and oxygen consumption of brown adipose tissue in the rat.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Male; Norepinephrine; Oxygen Consumption; Pyrilamine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1984 |
Analgesic effect of histamine induced by intracerebral injection into mice.
Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time | 1984 |
Bronchodilating activity of mequitazine.
Topics: Acetylcholine; Airway Resistance; Anaphylaxis; Animals; Aspirin; Atropine; Blood Pressure; Bronchial Spasm; Bronchodilator Agents; Dinoprostone; Guinea Pigs; Histamine; In Vitro Techniques; Male; Phenothiazines; Prostaglandins E; Pyrilamine; SRS-A | 1984 |
Direct and indirect effects of histamine on the smooth muscle cells of the guinea-pig main pulmonary artery.
Topics: Action Potentials; Animals; Cimetidine; Female; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Norepinephrine; Pulmonary Artery; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1983 |
Blockade of the acetylcholine-and histamine-induced changes in the permeability of the blood-brain barrier of normotensive and spontaneously hypertensive rats by atropine and pyrilamine.
Topics: Acetylcholine; Aminopyridines; Animals; Atropine; Blood Pressure; Blood-Brain Barrier; Female; Histamine; Hypertension; Male; Pyrilamine; Rats; Rats, Inbred Strains | 1983 |
Effects of histamine and the histamine antagonists mepyramine and cimetidine on human coronary arteries in vitro.
Topics: Adolescent; Adult; Aged; Aminopyridines; Child; Cimetidine; Coronary Vessels; Histamine; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Muscle Relaxation; Potassium; Pyrilamine | 1983 |
Involvement of H1 & H2 receptors in histamine-induced skin response in human.
Topics: Adult; Burimamide; Histamine; Humans; Male; Paresthesia; Premedication; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Skin | 1983 |
A possible mechanism of vasoactive agents on plasminogen activator release in isolated perfused pig ears.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Dilazep; Dose-Response Relationship, Drug; Drug Synergism; Ear, External; Histamine; In Vitro Techniques; Indomethacin; Papaverine; Perfusion; Plasminogen Activators; Pressure; Pyrilamine; Quinacrine; Swine; Thrombin; Vasoconstrictor Agents; Vasodilator Agents; Vasomotor System | 1983 |
Ocular disposition of topically applied histamine, cimetidine, and pyrilamine in the albino rabbit.
Topics: Administration, Topical; Aminopyridines; Animals; Aqueous Humor; Biological Availability; Ciliary Body; Cimetidine; Conjunctiva; Cornea; Eye; Histamine; Iris; Male; Pyrilamine; Rabbits | 1984 |
The influence of age on the distribution and activity of histamine receptors in the rat uterus.
Topics: Aging; Animals; Carbachol; Cimetidine; Electric Stimulation; Female; Histamine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Uterine Contraction; Uterus | 1984 |
Effect of histamine on aorta preparations of different species.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cats; Cimetidine; Guinea Pigs; Histamine; In Vitro Techniques; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pyrilamine; Rabbits; Rats; Species Specificity | 1984 |
Histamine regulation of prolactin secretion through H1- and H2-receptors.
Topics: Cimetidine; Histamine; Humans; Male; Prolactin; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Tachycardia; Thyrotropin-Releasing Hormone | 1982 |
The modification by ketotifen of respiratory responses to histamine and antigen in guinea-pigs.
Topics: Aerosols; Airway Resistance; Anesthesia; Animals; Antigens; Cromolyn Sodium; Guinea Pigs; Histamine; Ketotifen; Pyrilamine; Respiration | 1982 |
Effects of inhibitors of anaphylactic mediators in two models of bronchial anaphylaxis in anaesthetized guinea-pigs.
Topics: Anaphylaxis; Anesthesia; Animals; Bronchial Spasm; Guinea Pigs; Histamine; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiration | 1982 |
Pharmacological characterisation of extracts of coffee dusts.
Topics: Animals; Coffee; Dose-Response Relationship, Drug; Dust; Female; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Plant Extracts; Propranolol; Pyrilamine; Theophylline; Trachea | 1983 |
Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Cimetidine; Endothelium; Histamine; In Vitro Techniques; Male; Norepinephrine; Pyrilamine; Rats; Vasodilation | 1983 |
Distribution of histamine receptors in isolated canine airways.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Methylhistamines; Metiamide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Respiratory System; Tissue Distribution | 1983 |
Relaxation of isolated rabbit veins mediated by latent histamine H2-receptors.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H2; Veins | 1983 |
Studies on histamine-induced cutaneous flare in the guinea pig.
Topics: Anesthetics, Local; Animals; Blood Vessels; Capillary Permeability; Dermatitis; Guinea Pigs; Histamine; Lidocaine; Male; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Skin; Vasodilation | 1983 |
The effect of histamine, antihistamines, and a mast cell stabilizer on the growth of cloudman melanoma cells in DBA/2 mice.
Topics: Animals; Chromones; Cimetidine; Histamine; Histamine Antagonists; Immunosuppression Therapy; Male; Mast Cells; Melanoma; Methysergide; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Pyrilamine | 1983 |
Effect of histamine on microvascular permeability in the rat stomach.
Topics: Animals; Gastric Mucosa; Histamine; Male; Microcirculation; Microscopy, Fluorescence; Pyrilamine; Rats; Rats, Inbred Strains; Stomach; Television | 1983 |
Species difference in increased vascular permeability by synthetic leukotriene C4 and D4.
Topics: Animals; Arachidonic Acids; Bradykinin; Capillary Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Male; Prostaglandins E; Pyrilamine; Rabbits; Rats; Skin; Species Specificity; SRS-A | 1981 |
Histamine stimulate prostacyclin synthesis in cultured human umbilical vein endothelial cells.
Topics: Cimetidine; Dose-Response Relationship, Drug; Endothelium; Epoprostenol; Female; Histamine; Humans; Kinetics; Pregnancy; Prostaglandins; Pyrilamine; Umbilical Veins | 1980 |
Decrease in tumour growth by injections of histamine or serotonin in fibrosarcoma-bearing mice: influence of H1 and H2 histamine receptors.
Topics: Animals; Fibrosarcoma; Histamine; Male; Methysergide; Metiamide; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Sarcoma, Experimental; Serotonin | 1982 |
Measurement of canine gastric vascular permeability to plasma proteins in the normal and protein-losing states.
Topics: Animals; Blood Proteins; Capillary Permeability; Cimetidine; Dithiothreitol; Dogs; Fibrinogen; Gastric Mucosa; Histamine; Histamine Antagonists; Papaverine; Protein-Losing Enteropathies; Pyrilamine; Salicylates; Salicylic Acid; Serum Albumin, Radio-Iodinated | 1982 |
Decreased Schultz-Dale reaction in airways from sensitized guinea pigs treated with threshold concentrations of egg albumin in vivo.
Topics: Animals; Female; Guinea Pigs; Histamine; Hypersensitivity, Immediate; Lung; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Pyrilamine; Receptors, Histamine H1; SRS-A | 1982 |
High-affinity binding of [3H]doxepin to histamine H1-receptors in rat brain: possible identification of a subclass of histamine H1-receptors.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Doxepin; Histamine; In Vitro Techniques; Kinetics; Membranes; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1 | 1982 |
Effects of histamine on the resting and stimulation-induced release of [3H]-noradrenaline in guinea-pig isolated atria.
Topics: Animals; Atropine; Cimetidine; Cocaine; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Indomethacin; Male; Myocardium; Norepinephrine; Phentolamine; Propranolol; Pyrilamine | 1982 |
Histamine and gastric acid secretion in rabbits: mechanism of inhibition.
Topics: Aminopyridines; Animals; Blood Pressure; Catecholamines; Gastric Acid; Gastric Mucosa; Histamine; Pyrilamine; Rabbits; Stomach; Time Factors | 1982 |
Vascular endothelium and the relaxation effect of histamine on aorta of the rat.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Cimetidine; Endothelium; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Pyrilamine; Rats | 1982 |
Intra-arterial histamine increases blood-brain transport in rats.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Histamine; Injections, Intra-Arterial; Male; Metiamide; Microscopy, Electron; Pyrilamine; Rats; Rats, Inbred Strains; Sucrose; Water | 1982 |
Effects of histamine on brain capillaries. Fine structural and immunohistochemical studies after intracarotid infusion.
Topics: Animals; Capillaries; Capillary Permeability; Female; Histamine; Male; Metiamide; Microscopy, Electron; Parietal Lobe; Pinocytosis; Pyrilamine; Rats; Serum Albumin | 1982 |
Influence of temperature on sensitivity of histamine & its analogues in guinea pig tracheal chain.
Topics: Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Pyridines; Pyrilamine; Receptors, Histamine; Temperature; Trachea | 1982 |
A study on histamine tachyphylaxis on isolated chick oesophagus.
Topics: Acetylcholine; Animals; Atropine; Chickens; Esophagus; Female; Hemicholinium 3; Histamine; Ileum; In Vitro Techniques; Male; Morphine; Physostigmine; Pyrilamine; Serotonin; Tachyphylaxis | 1982 |
Effects of histamine on the circulatory system.
Topics: Animals; Cardiovascular System; Cats; Chlorpheniramine; Cimetidine; Dogs; Hemodynamics; Histamine; Humans; Pyrilamine; Time Factors | 1982 |
Role of histamine in the increased secretion of prolactin induced by ether in adult male rats.
Topics: Animals; Anterior Hypothalamic Nucleus; Cerebral Ventricles; Ether; Histamine; Male; Metiamide; Prolactin; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Secretory Rate; Stress, Physiological | 1982 |
Histamine H-1 receptors on rat peritoneal mast cells.
Topics: Aminopyridines; Animals; Ascitic Fluid; Binding, Competitive; Cimetidine; Diphenhydramine; Histamine; Male; Mast Cells; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1 | 1982 |
Inhibition of electrically induced twitch responses of the guinea-pig ileum by histamine.
Topics: Acetylcholine; Animals; Cimetidine; Electric Stimulation; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine | 1980 |
Uptake and metabolism of histamine in guinea-pig isolated atria and their relationship to the pharmacological responses.
Topics: Amodiaquine; Animals; Female; Guinea Pigs; Heart; Heart Rate; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Myocardium; Pyrilamine | 1980 |
Clonidine-induced lipolysis in dog adipocytes by stimulation of histamine (H2)-receptors.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Clonidine; Dogs; Histamine; Lipolysis; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Stimulation, Chemical; Theophylline | 1981 |
H2-Receptors mediate increases in permeability of the blood-brain barrier during arterial histamine infusion.
Topics: Animals; Blood-Brain Barrier; Brain; Functional Laterality; Histamine; Metiamide; Organ Specificity; Permeability; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H2 | 1981 |
Observation on the saliva and salivary gland extract of Haemaphysalis spinigera and Rhipicephalus sanguineus sanguineus.
Topics: Animals; Evans Blue; Female; Histamine; Immunization; Male; Pyrilamine; Rabbits; Saliva; Salivary Glands; Skin Tests; Ticks; Tissue Extracts | 1981 |
Reactivity of airway smooth muscles to bronchoactive agents in langur monkeys.
Topics: Animals; Bronchi; Carbachol; Cercopithecidae; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Pyrilamine; Serotonin; Trachea | 1981 |
Further characterization of the guinea pig left atrial tension response to histamine by use of selective agonists.
Topics: Animals; Female; Guinea Pigs; Heart Atria; Heart Rate; Histamine; In Vitro Techniques; Male; Methylhistamines; Myocardial Contraction; Pyridines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1981 |
Effect of histamine on motor function of opossum sphincter of Oddi.
Topics: Ampulla of Vater; Animals; Female; Histamine; Male; Methylhistamines; Metiamide; Motor Activity; Opossums; Pyridines; Pyrilamine; Receptors, Histamine H1; Sphincter of Oddi; Sympatholytics; Tetrodotoxin | 1981 |
Reactivity of isolated trachea, bronchus and lung strip of cats of carbachol, 5-hydroxytryptamine and histamine: evidence for the existence of methysergide-sensitive receptors.
Topics: Animals; Atropine; Bronchi; Carbachol; Cats; Histamine; In Vitro Techniques; Lung; Methysergide; Pyrilamine; Receptors, Serotonin; Serotonin; Trachea | 1981 |
Effects of inflammatory agents on endothelial lysosomal fragility and their inhibition by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Bradykinin; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Histamine; Humans; Indomethacin; Lysosomes; Prostaglandins E; Pyrilamine | 1981 |
[The effect of histamine on smooth muscle cells of the artery of the ear in rabbits].
Topics: Animals; Cimetidine; Female; Histamine; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2 | 1981 |
Species differences in histamine receptors in the seminal vesicle.
Topics: Animals; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phentolamine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Reserpine; Seminal Vesicles; Species Specificity | 1981 |
Effect of histamine on the gastric smooth muscles of guinea pig.
Topics: Acetylcholine; Animals; Cimetidine; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Stomach | 1981 |
Trans-synaptic modulation of histamine H-1 receptor development in rat brain.
Topics: Animals; Animals, Newborn; Brain; Diphenhydramine; Female; Histamine; Hypothalamus; Pregnancy; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Synapses | 1981 |
H1- and H2-histamine receptor antagonists and induced release of prolactin in male rats.
Topics: Animals; Dose-Response Relationship, Drug; Histamine; Male; Metiamide; Prolactin; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1980 |
Histamine pharmacology in airway smooth muscle from a canine model of asthma.
Topics: Airway Resistance; Anaphylaxis; Animals; Asthma; Dogs; Histamine; In Vitro Techniques; Methylhistamines; Metiamide; Muscle Contraction; Muscle, Smooth; Ovalbumin; Pyrilamine; Receptors, Histamine H2; Trachea | 1980 |
Lysophosphatidylserine-induced release of intra-cellular amines in mice.
Topics: Animals; Biogenic Amines; Histamine; In Vitro Techniques; Lysophospholipids; Mast Cells; Mice; Phosphatidylserines; Pyrilamine | 1980 |
A positive inotropic response of guinea pig isolated atria to histamine not mediated via H1 or H2 receptors.
Topics: Animals; Female; Guinea Pigs; Heart Atria; Histamine; In Vitro Techniques; Male; Metiamide; Myocardial Contraction; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Stimulation, Chemical; Temperature | 1980 |
Effects of histamine and histamine antagonists on the uptake and release of catecholamines and 5-HT in brain synaptosomes.
Topics: Animals; Brain; Dopamine; Histamine; Histamine Antagonists; Norepinephrine; Pyrilamine; Rats; Serotonin; Synaptosomes | 1980 |
Identification of histamine H1- and H-2-receptors by means of mepyramine, cimetidine and theophylline in the cardiovascular system of the dog.
Topics: Animals; Cardiovascular System; Cimetidine; Dogs; Female; Hemodynamics; Histamine; Male; Organ Specificity; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Theophylline | 1980 |
The effect of histamine and histamine antagonists on gastric acid secretion and mucosal blood flow in man.
Topics: Adult; Cimetidine; Dose-Response Relationship, Drug; Gastric Juice; Gastric Mucosa; Histamine; Histamine Antagonists; Humans; Male; Pyrilamine; Regional Blood Flow; Secretory Rate | 1980 |
Negligible potency of acetylcholine in increasing vascular permeability.
Topics: Acetylcholine; Animals; Bradykinin; Capillary Permeability; Histamine; Male; Prostaglandins E; Pyrilamine; Rabbits; Rats | 1980 |
Reactivity of trachea, bronchi, and lung strips to histamine and carbachol in rhesus monkeys.
Topics: Animals; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Histamine; In Vitro Techniques; Lung; Macaca mulatta; Male; Metiamide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine H2; Trachea | 1980 |
Histamine stimulates brain phospholipid turnover through a direct, H-1 receptor-mediated mechanism.
Topics: Animals; Brain; Catecholamines; Cimetidine; Histamine; Male; Mast Cells; Methylhistamines; p-Methoxy-N-methylphenethylamine; Phosphates; Phospholipids; Pyridines; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1; Reserpine | 1980 |
A dual action of histamine on isolated human pulmonary arteries.
Topics: Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Pulmonary Artery; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1980 |
Effects of histamine on porcine isolated myocardium: differentiation from effects on human tissue.
Topics: Adolescent; Adult; Analysis of Variance; Animals; Child; Cimetidine; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Ventricles; Histamine; Humans; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Propranolol; Pyrilamine; Swine | 1993 |
The contractile response of thiopental in large and small ovine airways.
Topics: Animals; Atropine; Bronchi; Bronchoconstriction; Carbachol; Cell Degranulation; Dexamethasone; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Release; Ileum; Male; Mast Cells; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Pyrilamine; Sheep; Thiopental; Trachea | 1994 |
Histaminergic neurons mediate restraint stress-induced activation of central 5-hydroxytryptaminergic neurons in the rat.
Topics: Animals; Benzothiazoles; Histamine; Histamine H2 Antagonists; Histidine Decarboxylase; Hydroxyindoleacetic Acid; Male; Methylhistidines; Neurons; Nucleus Accumbens; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Receptors, Histamine H1; Restraint, Physical; Serotonin; Suprachiasmatic Nucleus; Thiazoles | 1994 |
Possible participation of histamine H3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells.
Topics: Anaphylaxis; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; Histamine Release; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mast Cells; Methylhistamines; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Peritoneum; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3 | 1994 |
Substance P-induced histamine release in tracheally perfused guinea pig lungs.
Topics: Animals; Benzamides; Bronchoconstriction; Capsaicin; Guinea Pigs; Histamine; In Vitro Techniques; Lung; Male; Mast Cells; Perfusion; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P | 1995 |
Histamine enhances granulocyte-macrophage colony-stimulating factor and interleukin-6 production by human peripheral blood mononuclear cells.
Topics: Antibodies; Cell Adhesion; Cells, Cultured; Cimetidine; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interleukin-3; Interleukin-6; Kinetics; Leukocytes, Mononuclear; Pyrilamine; Radioimmunoassay; Ranitidine; Stem Cells; Stimulation, Chemical; Terfenadine | 1995 |
Recepto-secretory mechanism in histamine-stimulated amylase release from rat parotid gland.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Azepines; Calmodulin; Cimetidine; Culture Techniques; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Isoquinolines; Male; Myosin-Light-Chain Kinase; Parotid Gland; Piperazines; Protein Kinase C; Pyrilamine; Rats; Rats, Wistar; Sulfonamides | 1995 |
Antigen depolarizes guinea pig bronchial parasympathetic ganglion neurons by activation of histamine H1 receptors.
Topics: Animals; Antibodies; Bronchi; Chickens; Ganglia, Parasympathetic; Guinea Pigs; Histamine; Humans; Immunization, Passive; Male; Membrane Potentials; Neurons; Ovalbumin; Pyrilamine; Receptors, Histamine H1; Serum Albumin | 1995 |
In vivo and in vitro interaction of the novel selective histamine H1 receptor antagonist mizolastine with H1 receptors in the rodent.
Topics: Animals; Autoradiography; Benzimidazoles; Binding Sites; Binding, Competitive; Brain; Cerebellum; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Male; Mice; Muscle, Smooth; Phosphatidylinositols; Pyrilamine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Neurotransmitter | 1995 |
Histaminergic modulation of synaptic plasticity in area CA1 of rat hippocampal slices.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Hippocampus; Histamine; Long-Term Potentiation; Male; N-Methylaspartate; Pyrilamine; Rats; Rats, Wistar; Synaptic Transmission; Time Factors | 1995 |
Acute stimulation of glucose transport by histamine in cardiac microvascular endothelial cells.
Topics: Adenosine Diphosphate; Animals; Biological Transport; Cells, Cultured; Cimetidine; Coronary Vessels; Deoxyglucose; Endothelium, Vascular; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Histamine; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Pyrilamine; Rats; RNA, Messenger; Sulfhydryl Compounds | 1995 |
Posterior hypothalamic control of rabbit tracheal tension and involvement of central histaminergic neurons.
Topics: Animals; Blood Pressure; Cimetidine; Electric Stimulation; Histamine; Hypothalamus, Posterior; Muscle Contraction; Neurons; Pyrilamine; Rabbits; Trachea | 1995 |
Role of substance P in neurogenic inflammation in the rat incisor pulp and the lower lip.
Topics: Animals; Aspirin; Atropine; Bradykinin; Capillary Permeability; Cheilitis; Dental Pulp; Electric Stimulation; Histamine; Histamine Release; Incisor; Lip; Male; Mandibular Nerve; Methysergide; p-Methoxy-N-methylphenethylamine; Phentolamine; Propranolol; Pulpitis; Pyrilamine; Rats; Rats, Wistar; Substance P | 1993 |
Mechanism of histamine-induced calcium efflux from cultured bovine adrenal chromaffin cells: possible involvement of an Na+/Ca2+ exchange mechanism.
Topics: Adrenal Medulla; Amiloride; Animals; Calcium; Carrier Proteins; Cattle; Dose-Response Relationship, Drug; Extracellular Space; Histamine; Intracellular Fluid; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Sodium; Sodium-Calcium Exchanger | 1994 |
Mast cells and histamine contribute to bile acid-stimulated secretion in the mouse colon.
Topics: Animals; Bile Acids and Salts; Biological Transport; Chenodeoxycholic Acid; Chlorides; Colon; Diarrhea; Histamine; In Vitro Techniques; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pyrilamine; Tetrodotoxin; Ursodeoxycholic Acid; Water-Electrolyte Balance | 1995 |
Histamine directly stimulates gonadotropin-releasing hormone secretion from GT1-1 cells via H1 receptors coupled to phosphoinositide hydrolysis.
Topics: Animals; Binding Sites; Binding, Competitive; Cyclic AMP; Gonadotropin-Releasing Hormone; Histamine; Hydrolysis; Kinetics; Mice; Mice, Transgenic; Phosphatidylinositols; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Tritium; Tumor Cells, Cultured | 1995 |
Glucocorticoids enhance histamine-evoked catecholamine secretion from bovine chromaffin cells.
Topics: Androstanols; Animals; Base Sequence; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Cimetidine; Dexamethasone; Glucocorticoids; Histamine; Molecular Sequence Data; Pyrilamine; Receptors, Histamine H1; RNA, Messenger | 1995 |
Effect of histamine in autoimmune myocarditis mice.
Topics: Animals; Autoimmune Diseases; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Histamine; In Vitro Techniques; Mice; Myocardial Contraction; Myocarditis; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1994 |
Characterization and function of histamine receptors in corpus cavernosum.
Topics: Acetylcholine; Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Electric Stimulation; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Male; Methylhistamines; Muscle Contraction; Papaverine; Penis; Piperidines; Pyrilamine; Rabbits; Receptors, Histamine; Thiazoles | 1995 |
Interaction between histamine and adenosine in human cerebromicrovascular endothelial cells: modulation of second messengers.
Topics: Adenosine; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Endothelium, Vascular; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Pyrilamine; Receptors, Histamine; Receptors, Purinergic P1; Second Messenger Systems | 1994 |
Antiallergic effect of ZCR-2060: antihistaminic action.
Topics: Animals; Benzoates; Brain; Dermatitis, Contact; Exploratory Behavior; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hypersensitivity; In Vitro Techniques; Lung; Male; Membranes; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Sleep; Thiopental | 1994 |
Regulation of K+ conductance by histamine H1 and H2 receptors in neurones dissociated from rat neostriatum.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Histamine; Histamine Agonists; Impromidine; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Methylhistamines; Neostriatum; Potassium; Potassium Channels; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Triprolidine | 1994 |
Studies on responses to potassium, noradrenaline, serotonin, histamine and prostaglandin F2 alpha, of isolated pudendal arteries from non-lactating goats.
Topics: Animals; Arteries; Dinoprost; Goats; Histamine; In Vitro Techniques; Lactation; Mammary Glands, Animal; Muscle Contraction; Muscle Relaxation; Norepinephrine; Potassium; Pyrilamine; Receptors, Adrenergic, beta; Serotonin | 1994 |
Endogenous expression of histamine H1 receptors functionally coupled to phosphoinositide hydrolysis in C6 glioma cells: regulation by cyclic AMP.
Topics: Animals; Cyclic AMP; Glioma; Histamine; Histamine Agonists; Histamine H1 Antagonists; Hydrolysis; Lithium; Phosphatidylinositols; Pyrilamine; Rats; Receptors, Histamine H1; Tumor Cells, Cultured | 1994 |
The selective histamine H1-receptor agonist 2-(3-trifluoromethylphenyl)histamine increases waking in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Electrodes, Implanted; Histamine; Histamine Agonists; Injections, Intraventricular; Male; Pyrilamine; Rats; Rats, Wistar; Sleep; Wakefulness | 1994 |
Potentiation by 1,4-dithiothreitol of histamine-induced inositol phosphate formation in rat cerebral cortex and human HeLa cells.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Chromatography, Ion Exchange; Culture Techniques; Dithiothreitol; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; HeLa Cells; Histamine; Humans; Inositol Phosphates; Male; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1 | 1994 |
Activation of noradrenergic neurons projecting to the diencephalon following central administration of histamine is mediated by H1 receptors.
Topics: Animals; Benzothiazoles; Cerebral Ventricles; Diencephalon; Histamine; Histamine H2 Antagonists; Injections, Intraventricular; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Paraventricular Hypothalamic Nucleus; Phenoxypropanolamines; Piperidines; Preoptic Area; Pyrilamine; Rats; Receptors, Histamine H1; Thiazoles | 1994 |
Phenotypic and functional modulation of normal human alveolar macrophages by histamine.
Topics: Adult; Aged; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Enzyme-Linked Immunosorbent Assay; Female; Fibronectins; Histamine; Humans; Immunoenzyme Techniques; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lymphocyte Function-Associated Antigen-1; Macrophages, Alveolar; Male; Middle Aged; Phenotype; Pyrilamine; Receptors, IgE | 1994 |
Effects of histamine on inositol phosphates and intracellular Ca2+ in human glomerular epithelial cells.
Topics: Calcium; Cells, Cultured; Cimetidine; Cytophotometry; Enzyme Activation; Epithelial Cells; Epithelium; Histamine; Humans; Inositol Phosphates; Kidney Glomerulus; Protein Kinase C; Pyrilamine; Second Messenger Systems | 1994 |
Effects of antihistaminics on experimental brain edema.
Topics: Animals; Antioxidants; Benzothiazoles; Blood-Brain Barrier; Brain Edema; Dexamethasone; Freezing; Histamine; Histamine Antagonists; Histamine H2 Antagonists; Lipid Peroxidation; Male; Parietal Lobe; Phenoxypropanolamines; Piperidines; Pregnatrienes; Pyrilamine; Rats; Rats, Sprague-Dawley; Thiazoles; Water-Electrolyte Balance | 1994 |
Selective potentiation of histamine H1-receptor stimulated calcium responses by 1,4-dithiothreitol in DDT1MF-2 cells.
Topics: Adenosine; Animals; Bradykinin; Calcium; Cell Line; Cricetinae; Dithiothreitol; Drug Synergism; Histamine; Male; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1 | 1994 |
Histamine receptors mediating a positive inotropic effect in guinea pig and rabbit ventricular myocardium: distribution of the receptors and their possible intracellular coupling processes.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Guinea Pigs; Heart Ventricles; Histamine; Hydrolysis; Myocardial Contraction; Myocardium; Papillary Muscles; Phosphatidylinositols; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2 | 1994 |
Calcium-dependence of histamine- and carbachol-induced inositol phosphate formation in human U373 MG astrocytoma cells: comparison with HeLa cells and brain slices.
Topics: Animals; Astrocytoma; Brain Chemistry; Brain Neoplasms; Calcium; Calcium Channel Blockers; Carbachol; Cerebral Cortex; Guinea Pigs; HeLa Cells; Histamine; Humans; In Vitro Techniques; Inositol Phosphates; Lithium; Male; Nimodipine; omega-Conotoxin GVIA; Peptides; Pyrilamine; Rats; Rats, Wistar; Species Specificity; Tumor Cells, Cultured | 1994 |
Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current.
Topics: Cerebral Cortex; Cimetidine; Evoked Potentials; Histamine; Histamine Antagonists; Humans; Hypnotics and Sedatives; Membrane Potentials; Neurons; Piperidines; Potassium Channels; Pyrilamine; Receptors, Histamine H1 | 1994 |
Enhancement of cardiac performance of isolated working guinea pig heart by rabbit platelet and involvement of histamine.
Topics: Animals; Blood Platelets; Cimetidine; Guinea Pigs; Heart Rate; Histamine; In Vitro Techniques; Mast Cells; Myocardial Contraction; Pyrilamine; Rabbits | 1993 |
Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane.
Topics: Biological Transport; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Cell Line; Cell Membrane; Cytoplasm; Endoplasmic Reticulum; Endothelium, Vascular; Histamine; Humans; Imidazoles; Indoles; Ionomycin; Manganese; Pyrilamine | 1994 |
Evaluation of bronchoconstriction induced by neurokinins and its inhibition by selective nonpeptide antagonists in conscious guinea pigs, using a double-chamber plethysmograph technique.
Topics: Airway Resistance; Animals; Benzamides; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Histamine; Indomethacin; Leukotriene D4; Male; Neurokinin A; Parasympatholytics; Piperidines; Plethysmography; Propionates; Pyrilamine; Quinolines | 1994 |
Hypothalamo-preoptic histaminergic projections in sleep-wake control in the cat.
Topics: Animals; Brain; Cats; Dose-Response Relationship, Drug; Electroencephalography; Female; Histamine; Histidine Decarboxylase; Hypothalamus, Anterior; Impromidine; Male; Methylhistidines; Microinjections; Preoptic Area; Pyrilamine; Sleep; Sleep, REM; Time Factors; Wakefulness | 1994 |
Dehydration-induced release of vasopressin involves activation of hypothalamic histaminergic neurons.
Topics: Animals; Arginine Vasopressin; Blood; Cimetidine; Dehydration; Histamine; Hypothalamus; Male; Methylhistamines; Methylhistidines; Neurons; Osmolar Concentration; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 1994 |
Central mediation of tracheal pressure through H1 and H2 receptors after histamine administration to the fourth ventricle of anesthetized rabbit.
Topics: Animals; Atropine; Blood Pressure; Cimetidine; Histamine; Injections, Intraventricular; Phentolamine; Pressure; Pyrilamine; Rabbits; Receptors, Histamine H1; Receptors, Histamine H2; Trachea | 1994 |
Site-directed mutagenesis of the histamine H1 receptor: roles of aspartic acid107, asparagine198 and threonine194.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Base Sequence; CHO Cells; Cricetinae; Gene Expression; Histamine; Humans; Inositol Phosphates; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship; Threonine | 1994 |
Histamine-induced, central nervous system-mediated hyperglycemia is suppressed by atropine in the brain.
Topics: Animals; Atropine; Brain; Central Nervous System; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Hyperglycemia; Injections, Intraventricular; Male; Neurotransmitter Agents; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Dissociation between central and peripheral antihistamine activities of the new antiallergic agent N-[4-[4-(diphenylmethyl)-1-piperazinyl]-butyl]-3-(6-methyl-3-pyridyl) acrylamide in rats and monkeys.
Topics: Acrylamides; Animals; Brain; Central Nervous System; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Macaca fascicularis; Male; Piperazines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Skin | 1993 |
Changes in plasma adrenocorticotropic hormone and cortisol levels induced by intracerebroventricular injection of histamine and its related compounds in dogs.
Topics: Adrenocorticotropic Hormone; Animals; Cimetidine; Dogs; Hexamethonium; Hexamethonium Compounds; Histamine; Hydrocortisone; Hypophysectomy; Injections, Intraventricular; Male; Methylhistamines; Pyrilamine | 1993 |
The effects of chronic administration of chloroquine and quinacrine on the response of normal and denervated smooth muscle to agonist drugs.
Topics: Acetylcholine; Age Factors; Animals; Atropine; Chickens; Chloroquine; Culture Techniques; Dose-Response Relationship, Drug; Histamine; Male; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Potassium Chloride; Pyrilamine; Quinacrine; Serotonin; Synaptic Transmission | 1993 |
Desensitization of histamine H1 receptor-mediated inositol phosphate accumulation in guinea pig cerebral cortex slices.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Inositol Phosphates; Male; Pyrilamine; Receptors, Histamine H1 | 1993 |
Role of cysteinyl-leukotrienes and histamine in mediating intrinsic tone in isolated human bronchi.
Topics: Bronchi; Chlorpheniramine; Dicarboxylic Acids; Female; Histamine; Humans; Hydroxyurea; In Vitro Techniques; Indazoles; Isometric Contraction; Isotonic Solutions; Leukotriene D4; Lipoxygenase Inhibitors; Male; Middle Aged; Muscle Tonus; Muscle, Smooth; Pyrilamine; SRS-A | 1994 |
Role of mast cell histamine in brown adipose tissue thermogenic response to VMH stimulation.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Cimetidine; Electric Stimulation; Female; Histamine; Male; Mast Cells; Norepinephrine; Oxygen Consumption; Pyrilamine; Rats; Rats, Inbred Strains; Tissue Distribution; Ventromedial Hypothalamic Nucleus | 1994 |
Site-directed mutagenesis of the histamine H1-receptor reveals a selective interaction of asparagine207 with subclasses of H1-receptor agonists.
Topics: Animals; Asparagine; Base Sequence; Chlorpheniramine; DNA Primers; Guinea Pigs; Histamine; Histamine Agonists; Inositol Phosphates; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship | 1994 |
Intestinal mucosal lymphocytes have H1 receptors: H1 antagonists reduce their proliferation and cytotoxicity.
Topics: Cell Division; Cytotoxicity, Immunologic; Diphenhydramine; Epithelium; Histamine; Humans; In Vitro Techniques; Intestinal Mucosa; Pyrilamine; Receptors, Histamine H1; Tumor Cells, Cultured | 1994 |
Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea pigs.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchitis; Bronchoalveolar Lavage Fluid; Guinea Pigs; Histamine; Male; Methacholine Compounds; Ovalbumin; Pyrilamine; Respiratory Function Tests | 1994 |
Histamine lipolytic activity and semicarbazide-sensitive amine oxidase (SSAO) of rat white adipose tissue (WAT).
Topics: Adipose Tissue; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Cimetidine; Histamine; Isoproterenol; Kinetics; Lipolysis; Male; Methylhistamines; Pyrilamine; Rats; Rats, Wistar; Semicarbazides | 1993 |
Histamine stimulates normal human melanocytes in vitro: one of the possible inducers of hyperpigmentation in urticaria pigmentosa.
Topics: Adult; Cells, Cultured; Cimetidine; Glycoproteins; Histamine; Humans; Hyperpigmentation; Imidazoles; Male; Melanocytes; Membrane Glycoproteins; Monophenol Monooxygenase; Oxidoreductases; Pyrilamine; Reference Values; Urticaria Pigmentosa | 1993 |
Gestational changes in endothelium-dependent vasorelaxation in human umbilical artery.
Topics: Arginine; Biological Assay; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Histamine; Humans; In Vitro Techniques; Nitric Oxide; Nitroarginine; Nitroglycerin; Potassium; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pyrilamine; Superoxide Dismutase; Umbilical Arteries; Vasodilation | 1994 |
Histamine is not involved in pentagastrin-induced gastric mucosal vasodilation in the rat.
Topics: Animals; Blood Flow Velocity; Blood Vessels; Erythrocytes; Gastric Acid; Gastric Mucosa; Histamine; Injections, Intra-Arterial; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Pentagastrin; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Vasodilation | 1994 |
Histamine does not mediate mucosal permeability changes after subclinical intestinal ischemia-reperfusion injury.
Topics: Animals; Chromium Radioisotopes; Edetic Acid; Enterocolitis, Pseudomembranous; Histamine; Ileum; Intestinal Absorption; Intestinal Mucosa; Male; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Weaning | 1993 |
Locus of action of Ni2+ on histamine-induced inositol phosphate formation in brain slices and in HeLa cells.
Topics: Animals; Binding Sites; Brain; Carbachol; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; HeLa Cells; Histamine; Humans; In Vitro Techniques; Inositol Phosphates; Nickel; Phenoxybenzamine; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine | 1993 |
Characteristics of histamine H1 receptors on HeLa cells.
Topics: Binding Sites; Cell Membrane; Chlorpheniramine; HeLa Cells; Histamine; Humans; Inositol Phosphates; Pyrilamine; Receptors, Histamine H1 | 1993 |
Histamine evokes greater increases in phosphatidylinositol metabolism and catecholamine secretion in epinephrine-containing than in norepinephrine-containing chromaffin cells.
Topics: Adrenal Glands; Angiotensin II; Animals; Bradykinin; Catecholamines; Cattle; Chromaffin System; Epinephrine; Histamine; Inositol Phosphates; Norepinephrine; Phosphatidylinositols; Potassium; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate | 1993 |
Desensitization of histamine H1 receptor-mediated inositol phosphate production in HeLa cells.
Topics: Bradykinin; HeLa Cells; Histamine; Humans; Inositol; Inositol Phosphates; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sodium Fluoride | 1993 |
Effects of Pasteurella haemolytica culture supernate on bovine tracheal smooth muscle.
Topics: Animals; Atropine; Bacterial Toxins; Carbachol; Cattle; Culture Techniques; Cytotoxins; Diphenhydramine; Dose-Response Relationship, Drug; Exotoxins; Histamine; Mannheimia haemolytica; Muscle, Smooth; Pyrilamine; Trachea | 1993 |
Anti-immunoglobulin E-stimulated ion transport in human large and small intestine.
Topics: Antibodies, Anti-Idiotypic; Cells, Cultured; Colforsin; Cromolyn Sodium; Electric Stimulation; Histamine; Humans; Immunoglobulin E; Intestinal Absorption; Intestinal Mucosa; Intestine, Large; Intestine, Small; Ion Transport; Mast Cells; Piroxicam; Pyrilamine; Receptors, Histamine H1; Tetrodotoxin | 1993 |
Effect of histamine on memory retrieval in old rats.
Topics: Acetylcholine; Aging; Animals; Anticonvulsants; Avoidance Learning; Cerebrovascular Circulation; Cimetidine; Dose-Response Relationship, Drug; Exploratory Behavior; Histamine; Histamine Agonists; Injections, Intraventricular; Male; Memory; Methylhistamines; Motor Activity; Piperidines; Pyrilamine; Rats; Rats, Wistar | 1993 |
Histamine H3 receptor-mediated modulation of water consumption in the rat.
Topics: Animals; Drinking; Histamine; Histamine Antagonists; Male; Methylhistamines; Nicotinic Acids; Piperidines; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H3; Tetrazoles; Triazoles | 1993 |
Insulin/hypoglycemia-induced adrenocorticotropin and beta-endorphin release: involvement of hypothalamic histaminergic neurons.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cetirizine; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Male; Methylhistamines; Neurons; Pyrilamine; Pyrimidinones; Rats; Rats, Wistar | 1993 |
Cis-urocanic acid stimulates human peripheral blood monocyte prostaglandin E2 production and suppresses indirectly tumor necrosis factor-alpha levels.
Topics: Brompheniramine; Cells, Cultured; Cimetidine; Cyclic AMP; Dinoprostone; Diphenhydramine; Histamine; Humans; In Vitro Techniques; Interleukin-1; Interleukin-6; Lipopolysaccharides; Monocytes; Pyrilamine; Second Messenger Systems; Stereoisomerism; Tumor Necrosis Factor-alpha; Urocanic Acid | 1993 |
Denervation hypersensitivity of histamine H1-receptors in rat brain cortex.
Topics: Animals; Cerebral Cortex; Denervation; Histamine; Kinetics; Medial Forebrain Bundle; Phosphatidylinositols; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1 | 1993 |
Altered response to histamine in brain tumor vessels: the selective increase of regional cerebral blood flow in transplanted rat brain tumor.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebral Arteries; Cerebrovascular Circulation; Cimetidine; Glioma; Histamine; Infusions, Intra-Arterial; Male; Neoplasm Transplantation; Pyrilamine; Rats; Rats, Wistar | 1993 |
Characterization of histamine receptors in isolated pig basilar artery by functional and radioligand binding studies.
Topics: Animals; Basilar Artery; Cimetidine; Histamine; In Vitro Techniques; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Vasoconstriction | 1993 |
Mouse P19 embryonal carcinoma cells express functional histamine H1-receptors.
Topics: Animals; Binding, Competitive; Calcium; Cell Membrane; Fura-2; Histamine; Kinetics; Mice; Pyrilamine; Receptors, Histamine H1; Teratoma; Tumor Cells, Cultured | 1993 |
Adenosine is a mediator of ethanol-induced gastric vasodilation in dogs.
Topics: Adenosine; Animals; Cimetidine; Dogs; Ethanol; Histamine; Indomethacin; Male; Muscle, Smooth; Purinergic Antagonists; Pyrilamine; Regional Blood Flow; Stomach; Theophylline; Vascular Resistance; Vasodilation | 1993 |
Histamine H1 receptor binding sites in mouse uterine horns.
Topics: Animals; Cimetidine; Estrus; Female; Gonadal Steroid Hormones; Histamine; In Vitro Techniques; Kinetics; Membranes; Mice; Ovariectomy; Pregnancy; Pyrilamine; Receptors, Histamine H1; Uterus | 1993 |
Influence of the central histaminergic systems on the pituitary-adrenocortical response to met-enkephalinamide.
Topics: Adrenal Glands; Animals; Corticosterone; Dose-Response Relationship, Drug; Enkephalin, Methionine; Histamine; Hypothalamo-Hypophyseal System; Male; Pyrilamine; Rats; Rats, Wistar; Sodium Chloride | 1995 |
Inhibition of pulmonary hypertensive response after antigen challenge.
Topics: Animals; Antigens; Benzenesulfonates; Blood Pressure; Bronchoconstriction; Cycloheptanes; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Erythrocytes; Histamine; Histamine H1 Antagonists; Humans; Hypertension, Pulmonary; In Vitro Techniques; Indomethacin; Perfusion; Pulmonary Artery; Pyrilamine; Rabbits; Receptors, Thromboxane; Thromboxane A2 | 1995 |
Characteristics of the binding of [3H]-mepyramine to intact human U373 MG astrocytoma cells: evidence for histamine-induced H1-receptor internalisation.
Topics: Astrocytoma; Enzyme Activation; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Phosphoric Diester Hydrolases; Pyrilamine; Receptors, Histamine H1; Tritium; Tumor Cells, Cultured | 1995 |
Increases in cyclic AMP levels couple to H1 receptors in atria from autoimmune myocarditis mice.
Topics: Animals; Autoimmune Diseases; Cimetidine; Cyclic AMP; Heart Atria; Histamine; Histamine Agonists; Histamine Antagonists; Male; Mice; Myocarditis; Phosphatidylinositols; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Thiazoles | 1995 |
Involvement of central histamine in the early phase of ACTH and corticosterone responses to endotoxin in rats.
Topics: Adrenocorticotropic Hormone; Animals; Cimetidine; Corticosterone; Escherichia coli; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Kinetics; Lipopolysaccharides; Male; Median Eminence; Methylhistamines; Pyrilamine; Rats; Rats, Sprague-Dawley | 1996 |
Effect of oxitropium bromide on histamine-induced airway goblet cell secretion.
Topics: Administration, Inhalation; Aerosols; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Histocytochemistry; Injections, Intravenous; Male; Mucus; Muscarinic Antagonists; Piperidines; Pyrilamine; Receptors, Histamine; Scopolamine Derivatives; Trachea; Vagus Nerve | 1996 |
Receptor-mediated regulation by histamine of the acid phosphatase activity in cultured cerebral endothelial cells.
Topics: Acid Phosphatase; Animals; Cell Line; Cerebral Cortex; Endothelium; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indicators and Reagents; Molecular Weight; Nitrophenols; Organophosphorus Compounds; Pyrilamine; Ranitidine; Rats | 1996 |
Hippocampal somatostatin receptors and modulation of adenylyl cyclase activity in histamine-treated rats.
Topics: Adenylyl Cyclases; Animals; Cerebral Ventricles; Cimetidine; Colforsin; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hippocampus; Histamine; Injections, Intraperitoneal; Injections, Intraventricular; Kinetics; Pyrilamine; Rats; Rats, Wistar; Receptors, Somatostatin; Somatostatin; Time Factors | 1996 |
Endothelium-independent contractile and relaxant responses to histamine in the rabbit aorta and common carotid, mesenteric, renal, and femoral arteries.
Topics: Animals; Arteries; Endothelium, Vascular; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Metiamide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Pyrilamine; Rabbits | 1996 |
Chronic beta 1-adrenoceptor blockade sensitises the H1 and H2 receptor systems in human atrium: rôle of cyclic nucleotides.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; Famotidine; Female; Heart; Heart Atria; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Middle Aged; Myocardial Contraction; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Stimulation, Chemical | 1996 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |
A bizarre receptor mediating stimulatory effect of histamine on cyclic AMP formation in duck pineal gland.
Topics: Animals; Cyclic AMP; Ducks; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Methylhistamines; Pineal Gland; Pyrilamine; Ranitidine; Receptors, Histamine | 1995 |
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR.
Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Iris; Lethal Dose 50; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Piperidines; Potassium; Pyrilamine; Ranitidine; Receptors, Histamine H1; Substance P | 1996 |
Histamine enhanced the TNF-alpha-induced expression of E-selectin and ICAM-1 on vascular endothelial cells.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Dibenzoxepins; Diphenhydramine; Drug Interactions; E-Selectin; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Intercellular Adhesion Molecule-1; Ketotifen; Olopatadine Hydrochloride; Pyrilamine; Ranitidine; Tumor Necrosis Factor-alpha; Umbilical Veins | 1996 |
Contribution of mast cell mediators to alterations in macrophage function after malathion administration.
Topics: Administration, Oral; Animals; Cathepsin D; Cholinesterase Inhibitors; Cromolyn Sodium; Drug Interactions; Female; Histamine; Macrophages; Malathion; Mast Cells; Mice; Mice, Inbred C57BL; Phagocytosis; Pyrilamine; Respiratory Burst; Terpenes | 1996 |
Histamine augments VCAM-1 expression on IL-4- and TNF-alpha-stimulated human umbilical vein endothelial cells.
Topics: Amanitins; Antibodies, Blocking; Antigens, CD; Cell Adhesion; Cells, Cultured; Cimetidine; Eosinophils; Histamine; Histamine Antagonists; Humans; Immunohistochemistry; Integrin alpha4; Interleukin-4; Piperidines; Platelet Activating Factor; Pyrilamine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1996 |
Regulation of the human histamine H1 receptor stably expressed in Chinese hamster ovary cells.
Topics: Animals; Astrocytoma; Calcium; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Histamine; Humans; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1996 |
Effect of cetirizine on antigen-induced tracheal contraction of passively sensitized guinea pigs.
Topics: Animals; Anti-Allergic Agents; Antigens; Calcium; Cells, Cultured; Cetirizine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Lung; Male; Mast Cells; Mice; Mice, Inbred BALB C; Muscle Contraction; Pyrilamine; Trachea | 1996 |
Histamine activates phospholipase C in human airway epithelial cells via a phorbol ester-sensitive pathway.
Topics: Calcium; Calcium-Transporting ATPases; Cell Line; Cimetidine; Cystic Fibrosis; Enzyme Activation; Enzyme Inhibitors; Epithelium; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Inositol Phosphates; Pertussis Toxin; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Thapsigargin; Trachea; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Assessment of antihistaminic and antimuscarinic effects of optical isomers of ephedrine and methylephedrine by receptor binding assay in guinea pig ileal muscle.
Topics: Acetylcholine; Animals; Ephedrine; Guinea Pigs; Histamine; Ileum; Isomerism; Male; Pyrilamine; Quinuclidinyl Benzilate; Receptors, Histamine H1; Receptors, Muscarinic | 1996 |
Regulation of [Ca2+]i rise activated by doxepin-sensitive H1-histamine receptors in Jurkat cells, cloned human T lymphocytes.
Topics: Animals; Blotting, Northern; Blotting, Western; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Doxepin; GTP-Binding Proteins; Histamine; Humans; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Receptors, Histamine H1; T-Lymphocytes | 1996 |
"In vivo" and "in vitro" antitumoral action of Larrea divaricata Cav.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Division; Cimetidine; Cyclic AMP; Female; Histamine; Lymphoma, T-Cell; Mammary Neoplasms, Animal; Phytotherapy; Plant Extracts; Plants, Medicinal; Pregnancy; Propranolol; Pyrilamine; Rats; Thymidine | 1996 |
Hippocampus and learning: possible role of histamine receptors.
Topics: Animals; Evoked Potentials, Auditory; Hippocampus; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Learning; Male; Memory; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Reaction Time | 1996 |
G proteins of the Gq family couple the H2 histamine receptor to phospholipase C.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Baculoviridae; Binding, Competitive; Cell Membrane; COS Cells; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; Inositol Phosphates; Insecta; Male; Pertussis Toxin; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Recombinant Proteins; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Stimulation of formation of adenosine 3',5'-phosphate by histamine in myenteric ganglia isolated from guinea-pig small intestine.
Topics: Animals; Cimetidine; Cyclic AMP; Ganglia; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Intestine, Small; Male; Myenteric Plexus; Pyrilamine; Signal Transduction; Stimulation, Chemical; Tripelennamine | 1996 |
Hippocampal histamine receptors: possible role on the mechanisms of memory in the rat, II.
Topics: Animals; Avoidance Learning; Electroshock; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Memory; Microinjections; Pyrilamine; Ranitidine; Rats; Receptors, Histamine | 1996 |
Effect of maturation on allergen-induced airflow obstruction and airway plasma exudation in sensitized guinea pigs.
Topics: Age Factors; Airway Obstruction; Airway Resistance; Allergens; Animals; Asthma; Exudates and Transudates; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Immunization, Passive; Male; Ovalbumin; Pyrilamine; Respiratory System | 1997 |
Histamine H2 receptor-mediated airway goblet cell secretion and its modulation by histamine-degrading enzymes.
Topics: Amine Oxidase (Copper-Containing); Animals; Asthma; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycoproteins; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine N-Methyltransferase; Male; Methylhistamines; Mucus; Piperidines; Pyrilamine; Recombinant Proteins; Trachea | 1997 |
Effect of histaminergic drugs on integumental melanophores of adult Bufo melanostictus.
Topics: Animals; Bufonidae; Cell Aggregation; Histamine; Histamine Agents; In Vitro Techniques; Melanophores; Methylhistamines; Metiamide; Pyrilamine | 1996 |
Pharmacological properties of cardiovascular histamine H1 receptor binding sites: characterisation with 2-phenylhistamines.
Topics: Animals; Aorta; Binding Sites; Cattle; Dose-Response Relationship, Drug; Guanosine Triphosphate; Guinea Pigs; Heart; Histamine; Pyrilamine; Receptors, Histamine H1 | 1997 |
Histamine H1 receptors and inositol phosphate formation in rat thalamus.
Topics: Animals; Dose-Response Relationship, Drug; Histamine; Inositol Phosphates; Pyrilamine; Rats; Receptors, Histamine H1; Thalamus | 1997 |
Morphobiochemical studies on alpha-amylase secretion by pancreatic follicles of guinea pigs after the application of exogenous histamine.
Topics: alpha-Amylases; Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; L-Lactate Dehydrogenase; Male; Pancreas; Pyrilamine; Ranitidine | 1997 |
Studies on the novel antiallergic agent HSR-609: its penetration into the central nervous system in mice and guinea pigs and its selectivity for the histamine H1-receptor.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Benzoxepins; Binding, Competitive; Capillary Permeability; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Isotope Labeling; Lethal Dose 50; Lung; Male; Mice; Mice, Inbred ICR; Pyridines; Pyrilamine; Rats; Receptors, Histamine H1; Receptors, Muscarinic; Receptors, Serotonin; Reference Standards; Structure-Activity Relationship | 1997 |
Histamine mediates the muscle layer-specific responses in the isolated swine myometrium.
Topics: Animals; Dimaprit; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Muscle, Smooth; Myometrium; Pyrilamine; Receptors, Histamine; Swine; Uterine Contraction | 1997 |
This histamine-like effects of Phallusia nigra extract: evidences for direct activity at H1 receptors.
Topics: Animals; Atropine; Cyproheptadine; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Ileum; Male; Muscle Contraction; Pyrilamine; Receptors, Histamine H1; Tissue Extracts; Tubocurarine; Urochordata | 1997 |
Human mast cell tryptase: a stimulus of microvascular leakage and mast cell activation.
Topics: Animals; Capillary Permeability; Chromatography, Affinity; Chymases; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Heparin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hot Temperature; Humans; Inflammation Mediators; Injections, Intravenous; Lung; Mast Cells; Protease Inhibitors; Pyrilamine; Serine Endopeptidases; Skin; Tryptases | 1997 |
Evidence for the involvement of histaminergic neurones in the regulation of the rat oxytocinergic system during pregnancy and parturition.
Topics: Afferent Pathways; Animals; Cimetidine; Female; Histamine; Histamine Antagonists; Histidine Decarboxylase; In Situ Hybridization; Labor, Obstetric; Lactation; Mammillary Bodies; Neurons; Oxytocin; Paraventricular Hypothalamic Nucleus; Pregnancy; Pregnancy, Animal; Pyrilamine; Rats; Rats, Wistar; RNA, Messenger | 1997 |
Interaction of local anaesthetics with histamine H1 receptors in guinea-pig ileum.
Topics: Anesthetics, Local; Animals; Binding, Competitive; Chloroquine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Isotope Labeling; Male; Muscle Contraction; Muscle, Smooth; Procaine; Pyrilamine; Quinacrine; Receptors, Histamine H1; Structure-Activity Relationship; Tetracaine | 1997 |
H1 and H2 histamine receptors modulate osteoclastic resorption by different pathways: evidence obtained by using receptor antagonists in a rat synchronized resorption model.
Topics: Animals; Bone Resorption; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Degranulation; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histocytochemistry; Male; Mast Cells; Microcirculation; Osteoclasts; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 1997 |
[Possible involvement of histamine in humoral regulation of the spontaneous contractile activity of the chick embryo amnion].
Topics: Amnion; Animals; Chick Embryo; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Muscle Contraction; Muscle, Smooth; Promethazine; Pyrilamine | 1997 |
Neurokinin A-LI release after antigen challenge in guinea-pig bronchial tubes: influence of histamine and bradykinin.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Bronchi; Capsaicin; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Ovalbumin; Pyrilamine; Substance P; Trachea | 1997 |
Effect of histamine on human fibroblast in vitro.
Topics: Cell Division; Cells, Cultured; Cimetidine; Collagen; DNA; Fibroblasts; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Pyrilamine | 1997 |
Histamine H1 receptor activation blocks two classes of potassium current, IK(rest) and IAHP, to excite ferret vagal afferents.
Topics: Action Potentials; Animals; Diphenhydramine; Electric Conductivity; Ferrets; Histamine; Histamine Agonists; Histamine H1 Antagonists; Impromidine; Male; Methylhistamines; Neurons, Afferent; Nodose Ganglion; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Pyrilamine; Receptors, Histamine H1; Thiazoles; Vagus Nerve | 1997 |
Two components of blood-brain barrier disruption in the rat.
Topics: Animals; Arachidonic Acid; Blood-Brain Barrier; Bucladesine; Calcitonin Gene-Related Peptide; Cerebrovascular Circulation; Cimetidine; Cyclic AMP; Dura Mater; Female; Fluorescent Dyes; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Isoproterenol; Isoquinolines; Male; Pia Mater; Pyrilamine; Rats; Rats, Wistar; Sympathomimetics; Time Factors | 1997 |
Brain histamine mediates the bombesin-induced central activation of sympatho-adrenomedullary outflow.
Topics: Adrenal Medulla; Animals; Bombesin; Brain; Epinephrine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypothalamus; Injections, Intraventricular; Male; Norepinephrine; Pargyline; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Sympathetic Nervous System | 1997 |
Effects of acute glucose overload on histamine H2 receptor-mediated Ca2+ mobilization in bovine cerebral endothelial cells.
Topics: Animals; Bradykinin; Brain; Bucladesine; Calcium; Cattle; Cells, Cultured; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Histamine; Histamine Antagonists; Homeostasis; Microcirculation; Neomycin; Neurotransmitter Agents; Protein Kinase C; Pyrilamine; Ranitidine; Receptors, Histamine H2; Staurosporine | 1998 |
Endogenous histamine stimulates ischemically sensitive abdominal visceral afferents through H1 receptors.
Topics: Abdomen; Afferent Pathways; Animals; Bile Ducts; Blood Pressure; Cats; Chlorpheniramine; Dimaprit; Duodenum; Female; Gallbladder; Histamine; Histamine H1 Antagonists; Indomethacin; Ischemia; Male; Methylhistamines; Nerve Fibers; Neural Conduction; Pancreas; Pyrilamine; Receptors, Histamine H1 | 1997 |
Sensitization of the histamine H1 receptor by increased ligand affinity.
Topics: Animals; Calcium; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Histamine; Histamine H1 Antagonists; Kinetics; Ligands; Mice; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Tumor Cells, Cultured | 1998 |
Mast cell mediated ion transport in intestine from patients with and without inflammatory bowel disease.
Topics: Animals; Antibodies, Anti-Idiotypic; Colforsin; Colitis, Ulcerative; Crohn Disease; Histamine; Histamine H1 Antagonists; Humans; Immunoglobulin E; In Vitro Techniques; Intestinal Mucosa; Ion Transport; Mast Cells; Pyrilamine; Rabbits | 1997 |
Comparison of the effects of histamine and N(alpha)-methylhistamine on neuronal function in the guinea-pig oesophagus and ileum.
Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Imidazoles; In Vitro Techniques; Methylhistamines; Muscle, Skeletal; Muscle, Smooth; Neurons; Neurons, Afferent; Pyrilamine; Receptors, Cholinergic; Receptors, Neurokinin-1; Receptors, Neurokinin-3; Substance P; Tetrodotoxin; Thiourea; Vagus Nerve | 1997 |
Inhibitory effects of meta-iodo-benzylguanidine (MIBG) on endothelial histamine receptor binding.
Topics: 3-Iodobenzylguanidine; Binding, Competitive; Cells, Cultured; Choline; Cyclic GMP; Cytidine; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Humans; Inositol; Iodobenzenes; Nitric Oxide; Phospholipids; Propranolol; Pyrilamine; Receptors, Histamine H1; Serine; Umbilical Veins | 1998 |
A role for histamine and substance P in immediate allergic responses in guinea pig airways: characterization of MDL 108,207DA, a dual H1/NK-1 receptor antagonist.
Topics: Animals; Benzimidazoles; Bronchi; Capillary Permeability; CHO Cells; Cricetinae; Dipeptides; Drug Combinations; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indoles; Inositol Phosphates; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Ovalbumin; Pyrilamine; Pyrrolidines; Radioligand Assay; Receptors, Histamine H1; Receptors, Neurokinin-1; Respiratory Hypersensitivity; Skin Tests; Substance P; Trachea; Tumor Cells, Cultured | 1998 |
Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C.
Topics: Animals; Astrocytoma; Brain Neoplasms; Calcium; Cerebellum; Colforsin; Cyclic AMP; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Guinea Pigs; HeLa Cells; Histamine; Humans; Inositol Phosphates; Protein Kinase C; Pyrilamine; Substance P; Thapsigargin; Tritium; Tumor Cells, Cultured | 1998 |
Regulation of cerebral microvascular permeability by histamine in the anaesthetized rat.
Topics: Anesthesia, General; Animals; Capillary Permeability; Cerebrovascular Circulation; Cimetidine; Dimaprit; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Muscle, Smooth, Vascular; Pia Mater; Pyrilamine; Rats; Venules | 1998 |
The blockade of H1 receptors attenuates the suppression of feeding and diuresis induced by inhibition of histamine catabolism.
Topics: Animals; Brain Chemistry; Diuresis; Enzyme Inhibitors; Feeding Behavior; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Piperidines; Pyrilamine; Pyrimethamine; Ranitidine; Rats; Rats, Wistar; Water-Electrolyte Balance | 1998 |
Regulation of H1-receptor coupling and H1-receptor mRNA by histamine in bovine tracheal smooth muscle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cattle; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indoles; Indomethacin; Maleimides; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; RNA, Messenger; Trachea | 1998 |
Histamine potentiates leukotriene B4-induced leukocyte adhesion: a potential role of histamine1-receptor antagonism in allergic leukocyte recruitment.
Topics: Animals; Blood Proteins; Cell Adhesion; Cheek; Cricetinae; Drug Synergism; Histamine; Histamine H1 Antagonists; Inflammation; Leukocytes; Leukotriene B4; Microcirculation; Pyrilamine; Receptors, Histamine H1; Venules | 1997 |
Motor behavioural function for histamine-dopamine interaction in brain.
Topics: Animals; Benzazepines; Benzothiazoles; Brain; Brain Chemistry; Central Nervous System Stimulants; Dopamine Agents; Dopamine Antagonists; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Methamphetamine; Motor Activity; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Stereotyped Behavior; Thiazoles | 1998 |
Histamine-induced synthesis and secretion of nerve growth factor from astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cimetidine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Interleukin-1; Nerve Growth Factors; Pyrilamine; Rats; Rats, Wistar | 1998 |
Evidence that histamine is the principal pharmacological component of venom from an Australian wolf spider (Lycosa godeffroyi).
Topics: Animals; Aorta; Australia; Blood Pressure; Bronchoconstriction; Fluorometry; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyrilamine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spider Venoms; Vas Deferens | 1998 |
The role of histamine in platelet aggregation by physiological and immunological stimuli.
Topics: Blood Platelets; Calcium; Cell Membrane; Cytosol; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Histamine Release; Histidine Decarboxylase; Humans; Methylhistidines; Platelet Aggregation; Pyrilamine; Receptors, Histamine H1; Signal Transduction | 1998 |
Guanosine 5'-(gamma-[35S]thio)triphosphate autoradiography allows selective detection of histamine H3 receptor-dependent G protein activation in rat brain tissue sections.
Topics: Adenosine; Animals; Autoradiography; Basal Ganglia; Brain Chemistry; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Male; Piperidines; Protein Binding; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H3; Signal Transduction; Substantia Nigra; Sulfur Radioisotopes; Xanthines | 1998 |
Hippocampal histamine receptors and conflictive exploration in the rat: studies using the elevated asymmetric plus-maze.
Topics: Animals; Exploratory Behavior; Hippocampus; Histamine; Male; Maze Learning; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Receptors, Histamine | 1997 |
Evidence for hypernociception induction following histamine H1 receptor activation in rodents.
Topics: Animals; Histamine; Histamine Agonists; Histamine H1 Antagonists; Male; Mice; Nociceptors; Pain Measurement; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles | 1998 |
Histamine-induced adherence and migration of equine eosinophils.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Chemotaxis, Leukocyte; Chlorpheniramine; Eosinophils; Female; Fibronectins; Histamine; Histamine H1 Antagonists; Horses; Integrin alpha4beta1; Integrins; Male; Plastics; Pyrilamine; Receptors, Histamine; Receptors, Lymphocyte Homing; Surface Properties | 1998 |
Histamine sensitivity of mesenteric afferent nerves in the rat jejunum.
Topics: Afferent Pathways; Animals; Blood Pressure; Dimaprit; Histamine; Histamine Agonists; Histamine Antagonists; Jejunum; Muscle, Smooth; Nifedipine; Piperidines; Pyrilamine; Ranitidine; Rats; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Splanchnic Circulation | 1998 |
Histamine-induced gastric acid secretion in horses.
Topics: Animals; Female; Gastric Acid; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Horses; Male; Pyrilamine | 1998 |
Mechanisms of non-drowsiness after oral administration of TMK688, a novel antiallergic drug.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Capillary Permeability; Hexobarbital; Histamine; Histamine H1 Antagonists; Male; Mice; Mice, Inbred ICR; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Sleep; Sleep Stages | 1998 |
Ca2+/calmodulin-mediated regulation of agonist-induced sequestration of Gq protein-coupled histamine H1 receptors in human U373 MG astrocytoma cells.
Topics: Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Centrifugation, Density Gradient; Culture Media; Enzyme Inhibitors; GTP-Binding Proteins; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Hypertonic Solutions; Protein Kinase C; Pyrilamine; Receptor Aggregation; Receptors, Histamine H1; Tumor Cells, Cultured | 1998 |
Central histaminergic neurons regulate rabbit tracheal tension through the cervical sympathetic nerve.
Topics: Animals; Fluorescent Dyes; Histamine; Histamine H1 Antagonists; Hypothalamus; Immunohistochemistry; Injections, Intraventricular; Mammillary Bodies; Medulla Oblongata; Neurons; Phytohemagglutinins; Pyrilamine; Rabbits; Stilbamidines; Sympathetic Nervous System; Trachea | 1998 |
Analysis of an H1 receptor-mediated, zinc-potentiated vasoconstrictor action of the histidyl dipeptide carnosine in rabbit saphenous vein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnosine; Cimetidine; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Ketanserin; Methiothepin; Muscle Contraction; Muscle Relaxation; Pyrilamine; Rabbits; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Saphenous Vein; Serotonin Antagonists; Vasoconstrictor Agents; Zinc | 1998 |
Pharmacology of [3H]-pyrilamine binding and of the histamine-induced inositol phosphates generation, intracellular Ca2+ -mobilization and cytokine release from human corneal epithelial cells.
Topics: Calcium; Cells, Cultured; Collagenases; Cornea; Cytokines; Dinoprostone; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine H1 Antagonists; Humans; Inositol Phosphates; Interleukin-6; Interleukin-8; Kinetics; Matrix Metalloproteinase 1; Pyrilamine; Receptors, Histamine H1; Tritium | 1998 |
The role of histamine H1, H2 and H3 receptors on enteric ascending synaptic transmission in the guinea pig ileum.
Topics: Animals; Cimetidine; Dimaprit; Electric Stimulation; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; Male; Motor Neurons; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine; Synaptic Transmission | 1998 |
Histamine receptors in the skin melanophores of Indian bullfrog Rana tigerina.
Topics: Animals; Edetic Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Melanins; Melanophores; Methylhistamines; Metiamide; p-Methoxy-N-methylphenethylamine; Pyrilamine; Ranidae; Receptors, Histamine; Skin; Skin Pigmentation | 1998 |
Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine.
Topics: Animals; Blood Platelets; Calcium; Histamine; Histamine H1 Antagonists; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrilamine; Rabbits; Thromboxane B2 | 1997 |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase | 1999 |
Morphobiochemical investigations of the thyroid gland of the guinea pig after the application of some receptor antagonists and histamine.
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Guinea Pigs; Histamine; Histamine Antagonists; Ipratropium; L-Lactate Dehydrogenase; Male; Monoamine Oxidase; Muscarinic Antagonists; Pyrilamine; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Sodium-Potassium-Exchanging ATPase; Thyroid Gland; Thyroxine; Triiodothyronine | 1999 |
Role of the endothelium in the vasorelaxing influence of histamine on isolated human subcutaneous resistance arteries.
Topics: Adipose Tissue; Arteries; Cimetidine; Endothelium, Vascular; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Muscle Relaxation; Nitric Oxide; Pyrilamine | 1999 |
Histoenzymatic investigations of the thyroid gland of guinea pig after the application of some receptor antagonists and histamine.
Topics: Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histocytochemistry; L-Lactate Dehydrogenase; Male; Pyrilamine; Ranitidine; Receptors, Histamine; Shock; Thyroid Gland | 1999 |
Morphobiochemical studies on alpha-amylase secretion by parotid gland acini of guinea pigs after the application of exogenous histamine.
Topics: alpha-Amylases; Animals; Cytoplasmic Granules; Enzyme Precursors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histocytochemistry; L-Lactate Dehydrogenase; Male; Parotid Gland; Pyrilamine; Ranitidine | 1999 |
Exploratory behaviour after intra-accumbens histamine and/or histamine antagonists injection in the rat.
Topics: Animals; Arousal; Brain Mapping; Exploratory Behavior; Fear; Histamine; Histamine Antagonists; Injections; Male; Maze Learning; Motivation; Nucleus Accumbens; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Reaction Time; Social Environment | 1999 |
Histaminergic and catecholaminergic interactions in the central regulation of vasopressin and oxytocin secretion.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Cimetidine; Epinephrine; Histamine; Histamine Agonists; Hypothalamus; Imidazoles; Infusions, Parenteral; Male; Methylhistamines; Norepinephrine; Oxytocin; Pituitary Gland, Posterior; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H2; Thiazoles; Thiourea | 1999 |
Mechanisms of bradykinin-induced catecholamine release in pithed spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; Bradykinin; Catecholamines; Decerebrate State; Electric Stimulation; Histamine; Male; Pyrilamine; Rats; Rats, Inbred SHR; Vagotomy | 1999 |
Nasal hyperresponsiveness to histamine induced by repetitive exposure to cedar pollen in guinea-pigs.
Topics: Administration, Inhalation; Airway Resistance; Allergens; Animals; Atropine; Disease Models, Animal; Guinea Pigs; Histamine; Immunization; Male; Methacholine Chloride; Naphazoline; Nasal Cavity; Pollen; Pyrilamine; Reference Values; Respiratory Hypersensitivity; Rhinitis, Allergic, Perennial; Sensitivity and Specificity; Trees | 1999 |
Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists.
Topics: Animals; Binding, Competitive; Cell Line, Transformed; COS Cells; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Inositol Phosphates; Methylhistidines; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Recombinant Fusion Proteins | 2000 |
Effects of histamine and related compounds on regional cerebral blood flow in rats.
Topics: Animals; Benzothiazoles; Blood Pressure; Brain Chemistry; Dimaprit; Diphenhydramine; Drug Interactions; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Regional Blood Flow; Thiazoles; Time Factors | 1999 |
Ring-substituted histaprodifen analogues as partial agonists for histamine H(1) receptors: synthesis and structure-activity relationships.
Topics: Animals; Aorta; Cyclization; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Ileum; Imidazoles; Male; Muscle Contraction; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Structure-Activity Relationship | 2000 |
Mepyramine but not cimetidine or clobenpropit blocks pertussis toxin-induced histamine sensitization in rats.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cimetidine; Drug Interactions; Histamine; Histamine Antagonists; Imidazoles; Male; Pertussis Toxin; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Thiourea; Virulence Factors, Bordetella | 2000 |
Involvement of tyrosine phosphorylation in the positive inotropic effect produced by H(1)-receptors with histamine in guinea-pig left atrium.
Topics: Animals; Atrial Function; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Genistein; Guinea Pigs; Heart Atria; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Isoflavones; Isoproterenol; Male; Myocardial Contraction; Phosphorylation; Protein-Tyrosine Kinases; Pyrilamine; Receptors, Histamine H1; Time Factors; Tyrosine; Tyrphostins | 2000 |
Antiamnesic effect of metoprine and of selective histamine H(1) receptor agonists in a modified mouse passive avoidance test.
Topics: Amnesia; Animals; Avoidance Learning; Enzyme Inhibitors; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine N-Methyltransferase; Male; Memory; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Nootropic Agents; Piracetam; Pyrilamine; Pyrimethamine; Receptors, Histamine H1; Scopolamine; Thiazoles | 2000 |
Ca(2+)/calmodulin-mediated regulation of the desensitizing process in G(q) protein-coupled histamine H(1) receptor-mediated Ca(2+) responses in human U373 MG astrocytoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Astrocytoma; Calcineurin Inhibitors; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cyclosporine; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Okadaic Acid; Piperidines; Pyrilamine; Ranitidine; Receptors, Histamine H1; Sulfonamides; Tacrolimus; Tumor Cells, Cultured | 2000 |
The lack of compound 48/80-induced contraction in isolated trachea of mast cell-deficient Ws/Ws rats in vitro: the role of connective tissue mast cells.
Topics: Animals; Anti-Asthmatic Agents; Carbachol; Connective Tissue; Female; Histamine; Histamine H1 Antagonists; Histocytochemistry; Ketanserin; Male; Mast Cells; Muscle, Smooth; Nedocromil; p-Methoxy-N-methylphenethylamine; Parasympathomimetics; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Trachea | 2000 |
Actions of histamine on muscle and ganglia of the guinea pig gallbladder.
Topics: Adenosine Triphosphate; Animals; Dimaprit; Excitatory Postsynaptic Potentials; Female; Gallbladder; Gallbladder Emptying; Ganglia, Autonomic; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mast Cells; Membrane Potentials; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Patch-Clamp Techniques; Potassium Channels; Pyrilamine; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2 | 2000 |
Does the histaminergic system play a role in spinal nociception?
Topics: Animals; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Methylhistamines; Motor Neurons; Pain; Pyrilamine; Ranitidine; Rats; Spinal Cord; Synaptic Transmission | 2000 |
Histamine-induced calcium entry in rat cerebellar astrocytes: evidence for capacitative and non-capacitative mechanisms.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebellum; Chelating Agents; Electrophysiology; Fluorescent Dyes; Fura-2; Histamine; Histamine H1 Antagonists; Metals; Nifedipine; Pyrilamine; Rats; Rats, Inbred F344 | 2000 |
Histamine evoked sustained elevations of cytosolic Ca2+ in bovine adrenal chromaffin cells independently of Ca2+ entry.
Topics: Animals; Apamin; Calcium; Calcium Signaling; Cattle; Cells, Cultured; Chelating Agents; Chromaffin Cells; Cytophotometry; Dose-Response Relationship, Drug; Fluorescent Dyes; Fura-2; Histamine; Histamine H1 Antagonists; Membrane Potentials; Patch-Clamp Techniques; Pyrilamine; Time Factors | 2000 |
Modified histamine-induced NO-mediated relaxation in resistance arteries in pre-eclampsia.
Topics: Adult; Arteries; Atrial Natriuretic Factor; Cyclic GMP; Down-Regulation; Endothelium, Vascular; Famotidine; Female; Histamine; Humans; Isometric Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Pre-Eclampsia; Pregnancy; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Vascular Resistance; Vasodilation | 2000 |
Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats.
Topics: Acetates; Animals; Anti-Asthmatic Agents; Bronchi; Bronchial Spasm; Capillary Permeability; Cyclopropanes; Histamine; Histamine H1 Antagonists; Leukotriene D4; Male; Methysergide; Ovalbumin; Pyrilamine; Quinolines; Rats; Rats, Inbred BN; Respiratory Hypersensitivity; Serotonin; Serotonin Antagonists; Sulfides; Trachea | 2001 |
Involvement of central histaminergic neurons in polypnea induced by hyperthermia in rabbits.
Topics: Animals; Enzyme Inhibitors; Fever; Histamine; Histamine H1 Antagonists; Male; Methylhistidines; Neurons; Preoptic Area; Pyrilamine; Rabbits; Receptors, Histamine H1; Respiration | 2001 |
Histamine alters gene expression in cultured human nasal epithelial cells.
Topics: Cells, Cultured; Epithelial Cells; Gene Expression; Histamine; Histamine H2 Antagonists; Humans; Nasal Mucosa; Pyrilamine; Ranitidine; Receptors, Histamine H1; RNA, Messenger; Tumor Necrosis Factor-alpha | 2001 |
The major role of peripheral release of histamine and 5-hydroxytryptamine in formalin-induced nociception.
Topics: Animals; Anti-Asthmatic Agents; Cimetidine; Cromolyn Sodium; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Indoles; Male; Meclizine; Neurons, Afferent; Nociceptors; p-Methoxy-N-methylphenethylamine; Pain; Pain Measurement; Piperazines; Pyrilamine; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Tropisetron | 2001 |
Dopaminergic effects of histamine administration in the nucleus accumbens and the impact of H1-receptor blockade.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine H1 Antagonists; Homovanillic Acid; Male; Nucleus Accumbens; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Time Factors | 2001 |
Regulation of parasympathetic neurons by mast cells and histamine in the guinea pig heart.
Topics: Action Potentials; Animals; Cimetidine; Female; Ganglia, Parasympathetic; Guinea Pigs; Heart; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunohistochemistry; Male; Mast Cells; Microtubule-Associated Proteins; Neurons; Ovalbumin; Pyrilamine; Receptors, Histamine; Vagus Nerve | 2001 |
Histamine-Induced increases in intracellular free Ca2+ levels in hepatoma cells.
Topics: Biological Transport; Calcium; Carcinoma, Hepatocellular; Cimetidine; Cytosol; Extracellular Space; Fluorescent Dyes; Fura-2; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Inositol 1,4,5-Trisphosphate; Liver Neoplasms; Pyrilamine; Tumor Cells, Cultured | 2000 |
Comparison of cedar pollen-induced allergic rhinitis in passively and actively sensitized guinea pigs.
Topics: Airway Resistance; Animals; Guinea Pigs; Histamine; Histamine H1 Antagonists; Immunization, Passive; Leukotriene D4; Male; Nasal Provocation Tests; Pollen; Pyrilamine; Rhinitis, Allergic, Seasonal; Sneezing; Trees; Vaccination | 2001 |
VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzimidazoles; Capillary Permeability; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Ketotifen; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Muscle Contraction; Passive Cutaneous Anaphylaxis; Peripheral Nervous System; Piperazines; Pruritus; Pyrilamine; Rats; Rats, Wistar; Terfenadine; Thiazines | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
The H3 receptor is involved in cholecystokinin inhibition of food intake in rats.
Topics: Animals; Brain; Cholecystokinin; Dose-Response Relationship, Drug; Eating; Gastric Mucosa; Histamine; Histamine Agonists; Histamine Antagonists; Injections, Intraperitoneal; Male; Methylhistamines; Piperidines; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H3; Sincalide; Stomach | 2001 |
The effects of histamine and its antagonists on the cochlear microphonic and the compound action potential of the guinea pig.
Topics: Administration, Topical; Animals; Cimetidine; Cochlea; Dose-Response Relationship, Drug; Evoked Potentials; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Pyrilamine; Tympanic Membrane | 2001 |
Histamine H(1)-receptor activation of nuclear factor-kappa B: roles for G beta gamma- and G alpha(q/11)-subunits in constitutive and agonist-mediated signaling.
Topics: Animals; Binding, Competitive; Chlorocebus aethiops; COS Cells; Histamine; Histamine H1 Antagonists; Kinetics; NF-kappa B; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Transfection | 2001 |
Characterization of histamine-induced increases in intracellular free Ca2+ concentrations in Chang liver cells.
Topics: Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Line; Cimetidine; Extracellular Space; Fluorescent Dyes; Fura-2; Hepatocytes; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Kinetics; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Spectrometry, Fluorescence; Thapsigargin | 2001 |
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cells, Cultured; Cimetidine; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Granulation Tissue; Histamine; Histamine Antagonists; Immunohistochemistry; Indoles; Indomethacin; Inflammation; Isoquinolines; Lymphokines; Macrophages, Peritoneal; Male; Maleimides; Naphthalenes; Neovascularization, Pathologic; Piperidines; Protein Kinase C; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H2; RNA, Messenger; Specific Pathogen-Free Organisms; Sulfonamides; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Mechanism underlying histamine-induced intracellular Ca2+ movement in PC3 human prostate cancer cells.
Topics: Calcium; Calcium-Transporting ATPases; Endoplasmic Reticulum; Enzyme Inhibitors; Estrenes; Fluorescent Dyes; Fura-2; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Inositol 1,4,5-Trisphosphate; Ion Transport; Male; Phosphodiesterase Inhibitors; Prostatic Neoplasms; Pyrilamine; Pyrrolidinones; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases | 2001 |
ReN 1869, a novel tricyclic antihistamine, is active against neurogenic pain and inflammation.
Topics: Animals; Benzoquinones; Binding Sites; Calcitonin Gene-Related Peptide; Calcium; Calcium Channels; Capsaicin; Carrageenan; Central Nervous System; CHO Cells; Cricetinae; Disease Models, Animal; Edema; Extravasation of Diagnostic and Therapeutic Materials; Gene Expression; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Mice; Neurogenic Inflammation; Pain; Pain Measurement; Piperidines; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Species Specificity; Spinal Cord; Transfection; Tritium | 2002 |
Orexins activate histaminergic neurons via the orexin 2 receptor.
Topics: Animals; Arousal; Carrier Proteins; Histamine; Histamine H1 Antagonists; Histidine Decarboxylase; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Microscopy, Electron; Neurons; Neuropeptides; Orexin Receptors; Orexins; Pyrilamine; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide | 2002 |
Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells.
Topics: Astrocytoma; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Histamine; Histamine H1 Antagonists; Humans; Inositol Phosphates; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured; Type C Phospholipases | 2001 |
The recovery of the neurally evoked secretory response of rat colonic mucosa after irradiation is independent of mast cells.
Topics: Animals; Chymases; Colon; Electric Stimulation; Gamma Rays; Histamine; In Vitro Techniques; Intestinal Mucosa; Male; Mast Cells; Pyrilamine; Rats; Rats, Wistar; Serine Endopeptidases; Tetrodotoxin | 2002 |
Histamine-induced IL-6 and IL-8 production are differentially modulated by IFN-gamma and IL-4 in human keratinocytes.
Topics: Benzimidazoles; Cells, Cultured; Cimetidine; Dose-Response Relationship, Drug; Drug Combinations; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interferon-gamma; Interleukin-4; Interleukin-6; Interleukin-8; Keratinocytes; Pyrilamine | 2002 |
Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats.
Topics: Animals; Drug Synergism; Epilepsy; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histidine; Kindling, Neurologic; Male; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3 | 2002 |
Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs.
Topics: Acetylcholine; Amides; Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ketotifen; Lung; Lysophospholipids; Male; Muscle Contraction; Muscle, Smooth; Protein Serine-Threonine Kinases; Pyridines; Pyrilamine; rho-Associated Kinases; Structure-Activity Relationship | 2002 |
Elevated nasal mucosal G protein levels and histamine receptor affinity in a guinea pig model of nasal hyperresponsiveness.
Topics: Animals; Area Under Curve; Binding, Competitive; Blotting, Western; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Heterotrimeric GTP-Binding Proteins; Histamine; Histamine H1 Antagonists; Male; Nasal Mucosa; Pyrilamine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial | 2002 |
The initial inositol 1,4,5-trisphosphate response induced by histamine is strongly amplified by Ca(2+) release from internal stores in smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Androstadienes; Animals; Calcium; Carbachol; Cimetidine; Extracellular Space; Guinea Pigs; Histamine; Histamine Agonists; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Muscle, Smooth; Pyrilamine; Ryanodine; Thapsigargin; Type C Phospholipases; Urinary Bladder; Wortmannin | 2002 |
Histochemical and biochemical studies on the secretory mechanisms of some glands of guinea-pigs treated with histamine.
Topics: Adrenal Glands; Animals; Endocrine Glands; Exocrine Glands; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Ipratropium; Male; Muscarinic Antagonists; Pancreas; Parotid Gland; Pyrilamine; Ranitidine; Thyroid Gland; Tissue Fixation | 2002 |
The control effect of histamine on body temperature and respiratory function in IgE-dependent systemic anaphylaxis.
Topics: Allergens; Anaphylaxis; Animals; Blood Pressure; Body Temperature; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; Immunization, Passive; Immunoglobulin E; Mast Cells; Mice; Mice, Knockout; Pyrilamine; Respiratory Function Tests; Tidal Volume; Trinitrobenzenes | 2002 |
Yawning/cortical activation induced by microinjection of histamine into the paraventricular nucleus of the rat.
Topics: Animals; Blood Pressure; Cerebral Cortex; Electroencephalography; Electromyography; Heart Rate; Histamine; Histamine H1 Antagonists; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Stereotaxic Techniques; Yawning | 2002 |
Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.
Topics: Base Sequence; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Cimetidine; Dimaprit; DNA Primers; Female; Gene Expression Regulation; Histamine; Humans; Interleukin-16; Male; Methylhistamines; Polymerase Chain Reaction; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H2; Receptors, Histamine H4 | 2002 |
LPS-induced platelet response and rapid shock in mice: contribution of O-antigen region of LPS and involvement of the lectin pathway of the complement system.
Topics: Anaphylaxis; Animals; Blood Platelets; Complement Activation; Complement C4; Complement C5; Endotoxins; Escherichia coli; Histamine; Humans; Injections, Intravenous; Lectins; Lipopolysaccharides; Liver; Lung; Male; Mannose; Mannose-Binding Lectin; Mannose-Binding Protein-Associated Serine Proteases; Mast Cells; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred DBA; O Antigens; Ovalbumin; Pyrilamine; Serine Endopeptidases; Serotonin; Sesquiterpenes; Shock, Septic; Structure-Activity Relationship | 2002 |
Histamine H1 receptors in rat dorsal raphe nucleus: pharmacological characterisation and linking to increased neuronal activity.
Topics: Action Potentials; Animals; Brain Stem; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Inositol Phosphates; Male; Neurons; Pyrilamine; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Histamine H1; Serotonin | 2002 |
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases | 2002 |
The role of histamine in dural vessel dilation.
Topics: Animals; Blood Pressure; Dura Mater; Electric Stimulation; Enzyme Inhibitors; Famotidine; Histamine; Histamine Antagonists; Male; Meningeal Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H2; Time Factors; Vasodilation | 2002 |
Murine tumor necrosis factor-alpha sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine.
Topics: Animals; Anti-Inflammatory Agents; Biogenic Monoamines; Cimetidine; Corticosterone; Dexamethasone; Diphenhydramine; Histamine; Histamine Antagonists; Hypothalamus; Male; Mice; Pyrilamine; Receptors, Histamine; Shock; Tumor Necrosis Factor-alpha | 2002 |
Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Electrophoresis; GTP Phosphohydrolases; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Molecular Sequence Data; Protein Conformation; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Recombinant Proteins; Species Specificity; Tritium | 2003 |
Histaminergic modulation of the intact respiratory network of adult mice.
Topics: Animals; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypoxia; Medulla Oblongata; Mice; Mice, Inbred C57BL; Nerve Net; Neurons; Phrenic Nerve; Piperidines; Pons; Pyrilamine; Receptors, Histamine H3; Respiratory System | 2003 |
Molecular characterization of specific H1-receptor agonists histaprodifen and its Nalpha-substituted analogues on bovine aortic H1-receptors.
Topics: Animals; Aorta, Thoracic; Binding Sites; Cattle; GTP-Binding Proteins; GTPase-Activating Proteins; Histamine; Histamine Agonists; Male; Protein Binding; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship; Tritium | 2003 |
Abolition of arteriolar dilation but not constriction to histamine in cremaster muscle of eNOS-/- mice.
Topics: Animals; Arterioles; Cimetidine; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Platelet Endothelial Cell Adhesion Molecule-1; Pyrilamine; Receptors, Histamine; Signal Transduction; Vasoconstriction; Vasodilation | 2003 |
Effect of histamine on the permeability of the nasal mucosa in vivo.
Topics: Adult; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Horseradish Peroxidase; Humans; Male; Nasal Mucosa; Pyrilamine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial | 2003 |
Pro-cognitive effect of a selective histamine H1-receptor agonist, 2-(3-trifluoromethylphenyl)histamine, in the rat object recognition test.
Topics: Animals; Cognition; Histamine; Histamine Agonists; Injections, Intraventricular; Male; Memory, Short-Term; Pyrilamine; Rats; Rats, Wistar; Stimulation, Chemical | 2003 |
Thiomersal enhances the binding of histamine to the H1 receptor, but not histamine-stimulated inositol phosphate formation.
Topics: Animals; Anti-Infective Agents, Local; Cell Line; Cell Line, Tumor; Cerebellum; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Inhibitory Concentration 50; Inositol Phosphates; Protein Binding; Pyrilamine; Receptors, Histamine H1; Thimerosal | 2003 |
Influence of histamine, cimetidine and pyrilamine on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Histamine; Histamine H2 Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Prazosin; Propranolol; Pyrilamine; Receptors, Histamine H2; Yohimbine | 2003 |
The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine.
Topics: Animals; Arthritis, Experimental; Bone Density; Bone Resorption; Cartilage, Articular; Cell Differentiation; Cimetidine; Dimaprit; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Osteoclasts; Pyrilamine; Rats; Rats, Inbred Lew | 2003 |
Effects of endogenous histamine on seizure development of pentylenetetrazole-induced kindling in rats.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Histamine; Histamine Release; Histidine; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Pentylenetetrazole; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Seizures; Thiourea | 2003 |
Mechanism of anti-nociceptive effects of Asarum sieboldii Miq. radix: potential role of bradykinin, histamine and opioid receptor-mediated pathways.
Topics: Analgesics, Non-Narcotic; Animals; Asarum; Bradykinin; Carrageenan; Edema; Guinea Pigs; Histamine; Ileum; Inflammation; Korea; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Plant Roots; Pyrilamine; Rats; Rats, Sprague-Dawley | 2003 |
Interactions among three classes of mediators explain antigen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchoconstriction; Cysteine; Drug Interactions; Guinea Pigs; Histamine; Histamine Antagonists; Leukotriene D4; Leukotrienes; Lung; Male; Ovalbumin; Perfusion; Pyrilamine; Thromboxanes | 2003 |
Histamine and prostaglandin interaction in regulation of oxytocin and vasopressin secretion.
Topics: Animals; Cimetidine; Cyclooxygenase Inhibitors; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypothalamus; Indomethacin; Lipopolysaccharides; Male; Oxytocin; Prostaglandin Antagonists; Prostaglandins; Pyrilamine; Rats; Rats, Wistar; Vasopressins | 2003 |
Measurement of the duration of action of N-p-chlorbenzhydryl-N'-m-methyl-benzyl-piperazine dihydrochloride (meclozine) and 2-[2-dimethylamino-ethyl) (p-methoxy-benzy) amino] pyridine (pyrilamine) against histamine microschock in guinea pigs.
Topics: Animals; Anti-Allergic Agents; Guinea Pigs; Histamine; Histamine Agents; Histamine H1 Antagonists; Meclizine; Piperazine; Piperazines; Pyridines; Pyrilamine | 1954 |
5-Hydroxytryptamine and histamine as mediators of the vascular injury produced by agents which damage mast cells in rats.
Topics: Animals; Blood Vessels; Edema; Histamine; Male; Mast Cells; Pyrilamine; Rats; Serotonin; Serotonin Antagonists; Vascular System Injuries; Wounds and Injuries | 1956 |
Some inhibitors of histamine-induced and formaldehyde-induced inflammation in mice.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Cortisone; Edema; Formaldehyde; Histamine; Inflammation; Mice; Pyrilamine; Sodium Salicylate | 1961 |
On the nature of the chemical mediators involved in anaphylactic reactions in mice.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Capillary Permeability; Chlorpromazine; Histamine; Histamine H1 Antagonists; Lysergic Acid Diethylamide; Mice; Passive Cutaneous Anaphylaxis; Promethazine; Pyrilamine; Serotonin | 1963 |
STIMULANT ACTIONS OF VOLATILE ANAESTHETICS ON SMOOTH MUSCLE.
Topics: Acetylcholine; Anesthetics; Animals; Anti-Allergic Agents; Central Nervous System Stimulants; Chloroform; Cocaine; Epinephrine; Ether; Ethers; Guinea Pigs; Halothane; Hexamethonium Compounds; Histamine; Histamine H1 Antagonists; Ileum; Muscle Contraction; Muscle, Smooth; Nicotine; Pharmacology; Pyrilamine; Research; Trichloroethylene | 1964 |
THE EFFECT OF VARYING CALCIUM CONCENTRATION ON THE KINETIC CONSTANTS OF HYOSCINE AND MEPYRAMINE ANTAGONISM.
Topics: Anti-Allergic Agents; Calcium; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Pharmacology; Pyrilamine; Research; Scopolamine | 1965 |
Suppressive effects of pyrilamine maleate and d-lysergic acid diethylamide (LSD-25) on early corneal lesions produced in vitro by Newcastle disease virus (NDV) and compound 48/80.
Topics: Animals; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Lysergic Acid Diethylamide; Newcastle Disease; Newcastle disease virus; p-Methoxy-N-methylphenethylamine; Pyrilamine | 1960 |
Submucosal microinfusion of endothelin and adrenaline mobilizes ECL-cell histamine in rat stomach, and causes mucosal damage: a microdialysis study.
Topics: Animals; Cells, Cultured; Endothelins; Enterochromaffin-like Cells; Epinephrine; Female; Gastric Mucosa; Gastrins; Histamine; Histamine Release; Histidine Decarboxylase; Infusions, Parenteral; Male; Methylhistidines; Microdialysis; Microinjections; Misoprostol; Omeprazole; Parietal Cells, Gastric; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Somatostatin; Time Factors | 2003 |
Serotonergic and histaminergic mechanisms involved in intralipid drinking?
Topics: Aminopyridines; Animals; Cyproheptadine; Dietary Fats; Dose-Response Relationship, Drug; Drinking Behavior; Eating; Histamine; Histamine H1 Antagonists; Hyperphagia; Indoles; Male; Metergoline; Pyrilamine; Rats; Serotonin; Serotonin Antagonists | 2003 |
Signaling via histamine receptors in cat duodenal smooth muscle cells.
Topics: Alkaloids; Animals; Benzophenanthridines; Cats; Duodenum; Enzyme Inhibitors; Ethylmaleimide; Famotidine; Heparin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Muscle Contraction; Myocytes, Smooth Muscle; Pertussis Toxin; Phenanthridines; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Signal Transduction | 2003 |
[Pyranisamine and antihistamines].
Topics: Anti-Allergic Agents; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Pyrilamine | 1950 |
The action of anthisan on the intestinal secretion produced by histamine and carbaminoylcholine.
Topics: Anti-Allergic Agents; Histamine; Histamine Agents; Histamine H1 Antagonists; Intestinal Secretions; Intestines; Pyrilamine | 1952 |
Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.
Topics: Animals; Binding Sites; Cells, Cultured; Chlorocebus aethiops; COS Cells; DNA Mutational Analysis; Dose-Response Relationship, Drug; Genes, Reporter; Histamine; Histamine Agonists; Mutagenesis, Site-Directed; NF-kappa B; Pyrilamine; Receptors, Histamine H1; Transfection | 2004 |
Glutamic acid and histamine-sensitive neurons in the ventral hippocampus and the basolateral amygdala of the rat: functional interaction on memory and learning processes.
Topics: Amygdala; Animals; Behavior, Animal; Drug Interactions; Escape Reaction; Glutamic Acid; Hippocampus; Histamine; Histamine H1 Antagonists; Learning; Male; Memory; Neurons; Pyrilamine; Rats; Reaction Time | 2004 |
Degranulation of mast cells located in median eminence in response to compound 48/80 evokes adrenocortical secretion via histamine and CRF in dogs.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cell Degranulation; Chromatography, Thin Layer; Corticotropin-Releasing Hormone; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Hemodynamics; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrocortisone; Injections, Intraventricular; Ketotifen; Male; Median Eminence; Metiamide; p-Methoxy-N-methylphenethylamine; Pyrilamine; Splanchnic Circulation | 2004 |
Pharmacological and histopathological characterization of Bothrops lanceolatus (Fer de lance) venom-induced edema.
Topics: Adrenergic beta-Antagonists; Animals; Antiemetics; Arachidonic Acid; Bothrops; Bradykinin; Cardiovascular Agents; Crotalid Venoms; Dexamethasone; Dose-Response Relationship, Drug; Edema; Edetic Acid; Extremities; Histamine; Histamine H1 Antagonists; Indomethacin; Mast Cells; Methysergide; Pyrilamine; Rats; Rats, Wistar; Serotonin; Time Factors; Vasoconstrictor Agents | 2004 |
Acute anthisan poisoning; report of a fatal case.
Topics: Histamine; Humans; Pyrilamine | 1950 |
NEW and nonofficial remedies: pyranisamine maleate; neo-antergan maleate.
Topics: Cyproheptadine; Histamine; Maleates; Pyrilamine | 1950 |
Role of the histamine system in nefopam-induced antinociception in mice.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Enzyme Inhibitors; Formaldehyde; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Methylhistamines; Methylhistidines; Mice; Mice, Inbred ICR; Nefopam; Pain Measurement; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3 | 2004 |
Homologous and heterologous phosphorylations of human histamine H1 receptor in intact cells.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Cyclic GMP; Histamine; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Pyrilamine; Receptor, Muscarinic M3; Receptors, Histamine H1; Tetradecanoylphorbol Acetate | 2004 |
Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.
Topics: Animals; Capsaicin; DNA; Gastric Mucosa; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Immersion; Interleukin-1; Male; Neurons, Afferent; Piperidines; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Regional Blood Flow; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 2005 |
Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists.
Topics: Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Female; Histamine; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Kinase C; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; STAT1 Transcription Factor; Trans-Activators; Tripelennamine | 2005 |
Histamine excites noradrenergic neurons in locus coeruleus in rats.
Topics: Action Potentials; Animals; Blotting, Northern; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Locus Coeruleus; Male; Neurons; Norepinephrine; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2005 |
Mast cell mediators in citric acid-induced airway constriction of guinea pigs.
Topics: Administration, Inhalation; Animals; Bronchoconstriction; Citric Acid; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Indoles; Indomethacin; Leukotriene C4; Mast Cells; p-Methoxy-N-methylphenethylamine; Prostaglandins; Pyrilamine; Serotonin | 2005 |
Assessment of the influence of histaminergic actions on cocaine-like effects of 3alpha-diphenylmethoxytropane analogs.
Topics: Animals; Benztropine; Binding, Competitive; Brain; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Guanidines; Histamine; Histamine Agonists; Histamine H1 Antagonists; In Vitro Techniques; Male; Methylhistamines; Motor Activity; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Tropanes | 2005 |
Cross state-dependent retrieval between histamine and lithium.
Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine H1 Antagonists; Injections, Intraventricular; Lithium; Male; Memory; Mice; Mice, Inbred Strains; Pyrilamine; Ranitidine; Time Factors | 2005 |
Effects of intracerebroventricular administration of ultra low doses of histaminergic drugs on morphine state-dependent memory of passive avoidance in mice.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine Agents; Imidazoles; Injections, Intraventricular; Male; Memory; Mice; Morphine; Morphine Dependence; Pyrilamine; Reaction Time; Thiourea | 2006 |
Involvement of the βγ subunits of G proteins in the cAMP response induced by stimulation of the histamine H1 receptor.
Topics: Adenylyl Cyclases; Animals; beta-Adrenergic Receptor Kinases; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Inositol Phosphates; Pyrilamine; Receptors, Histamine H1; Signal Transduction; Transfection | 2005 |
Intracerebroventricular effects of histaminergic agents on morphine-induced anxiolysis in the elevated plus-maze in rats.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Drug Interactions; Histamine; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Microinjections; Morphine; Narcotics; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Stereotaxic Techniques | 2005 |
The effects of histaminergic agents in the central amygdala of rats in the elevated plus-maze test of anxiety.
Topics: Amygdala; Animals; Anxiety; Histamine; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Microinjections; Pyrilamine; Ranitidine; Rats; Stereotaxic Techniques | 2005 |
Enhanced histamine-mediated contraction of rabbit penile dorsal artery in diet-induced hypercholesterolemia.
Topics: Animals; Arteries; Cholesterol, Dietary; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypercholesterolemia; Male; Muscle, Smooth, Vascular; Norepinephrine; Penis; Pyrilamine; Rabbits; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Histamine ameliorates spatial memory deficits induced by MK-801 infusion into ventral hippocampus as evaluated by radial maze task in rats.
Topics: Animals; Cimetidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Injections, Intraventricular; Male; Maze Learning; Memory Disorders; Pyrilamine; Rats; Rats, Sprague-Dawley | 2005 |
Histamine increases sickle erythrocyte adherence to endothelium.
Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules | 2006 |
Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.
Topics: Animals; Cell Death; Cells, Cultured; Coculture Techniques; Convulsants; Hippocampus; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus, Anterior; Hypothalamus, Posterior; Imidazoles; Kainic Acid; Methylhistidines; Microscopy, Confocal; Neurons; Neuroprotective Agents; Organ Culture Techniques; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H3; Thiourea; Triprolidine | 2006 |
Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Kinetics; Male; Oxytocin; Piperidines; Pituitary Gland, Posterior; Pyrilamine; Rats; Tissue Culture Techniques; Vasopressins | 2006 |
The effects of histaminergic agents in the ventral hippocampus of rats in the plus-maze test of anxiety-like behaviours.
Topics: Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hippocampus; Histamine; Histamine Agents; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Maze Learning; Microinjections; Pyrilamine; Ranitidine; Rats; Rats, Wistar | 2006 |
Histamine modulates mast cell degranulation through an indirect mechanism in a model IgE-mediated reaction.
Topics: Animals; beta-N-Acetylhexosaminidases; Cell Degranulation; Cimetidine; Female; Flow Cytometry; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunoglobulin E; Immunohistochemistry; Macrophages; Mast Cells; Nitric Oxide; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Pyrilamine; Rats; Rats, Wistar; Toxocara canis; Toxocariasis; Tumor Necrosis Factor-alpha | 2006 |
Histamine signaling through the H(2) receptor in the Peyer's patch is important for controlling Yersinia enterocolitica infection.
Topics: Animals; Anti-Allergic Agents; Anti-Ulcer Agents; Cimetidine; Dimaprit; Female; Gene Expression Profiling; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine Decarboxylase; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Omeprazole; Peyer's Patches; Pyrilamine; Receptors, Histamine H2; Signal Transduction; Survival Rate; Yersinia enterocolitica; Yersinia Infections | 2006 |
Histaminergic receptors of medial septum and conditioned place preference: D1 dopamine receptor mechanism.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Conditioning, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine; Receptors, Histamine; Septum of Brain; Sulpiride | 2006 |
Involvement of substance P and neurogenic inflammation in arsenic-induced early vascular dysfunction.
Topics: Analgesics; Animals; Arsenites; Capillary Permeability; Capsaicin; Ear; Endothelium, Vascular; Environmental Pollutants; Histamine; Histamine H1 Antagonists; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Neurogenic Inflammation; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Pyrilamine; Receptors, Neurokinin-1; Skin; Sodium Compounds; Substance P; Time Factors | 2007 |
The effects of histaminergic agents in the dorsal hippocampus of rats in the elevated plus-maze test of anxiety.
Topics: Animals; Anxiety; Hippocampus; Histamine; Male; Maze Learning; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 2006 |
Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Diphenhydramine; Donepezil; Ginkgo biloba; Histamine; Histamine H1 Antagonists; Indans; Male; Maze Learning; Memory; Memory Disorders; Muscarinic Antagonists; Neural Pathways; Nootropic Agents; Piperidines; Plant Extracts; Pyrilamine; Rats; Rats, Wistar; Scopolamine; Synaptic Transmission; Treatment Outcome | 2007 |
Potentiation by neuropeptide Y of histamine H1 receptor-mediated contraction in rat blood vessels.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Male; Neomycin; Neuropeptide Y; Phenylcarbamates; Pyrilamine; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine H1; Receptors, Neuropeptide; RNA, Messenger; Type C Phospholipases; Vasoconstriction; Vasoconstrictor Agents; Veins | 2007 |
Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway.
Topics: Afferent Pathways; Amidines; Animals; Blotting, Northern; Carotid Body; Chemoreceptor Cells; Female; Gene Expression; Histamine; Histamine Antagonists; Histidine Decarboxylase; Immunohistochemistry; Male; Medulla Oblongata; Microscopy, Immunoelectron; Phrenic Nerve; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine; Respiration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Cyanide | 2006 |
Contributions of histamine, prostanoids, and neurokinins to edema elicited by edema toxin from Bacillus anthracis.
Topics: Animals; Antigens, Bacterial; Aprepitant; Bacillus anthracis; Bacterial Toxins; Capillary Permeability; Celecoxib; Cell Degranulation; Cell Line; Disease Models, Animal; Edema; Enzyme Inhibitors; Histamine; Histamine H1 Antagonists; Humans; Indomethacin; Injections, Intradermal; Mast Cells; Morpholines; Neurokinin-1 Receptor Antagonists; Prostaglandin Antagonists; Prostaglandins; Pyrazoles; Pyrilamine; Rabbits; Substance P; Sulfonamides; Tachykinins | 2007 |
Stimulation of histamine H1 receptor up-regulates histamine H1 receptor itself through activation of receptor gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Carbazoles; Cyclic GMP; Enzyme Inhibitors; HeLa Cells; Histamine; Histamine H1 Antagonists; Humans; Indoles; Luciferases; Protein Kinase C; Pyrilamine; Pyrroles; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Transfection; Tritium; Up-Regulation | 2007 |
Role of hippocampal H1 receptors in radial maze performance and hippocampal theta activity in rats.
Topics: Animals; Behavior, Animal; Hippocampus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Male; Maze Learning; Memory; Motor Activity; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Statistics as Topic; Theta Rhythm | 2007 |
Differential effects of histamine on Leydig cell and testicular macrophage activities in wall lizards: precise role of H1/H2 receptor subtypes.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Famotidine; Histamine; Histamine Antagonists; Leydig Cells; Lizards; Macrophages; Male; Phagocytosis; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Superoxides; Testosterone | 2007 |
Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Cloning, Molecular; GTP Phosphohydrolases; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Molecular Sequence Data; Phylogeny; Pyrilamine; Rats; Receptors, Histamine H1; Recombinant Proteins; Sequence Alignment | 2008 |
Comparison of anthisan (mepyramine maleate) and phenergan as histamine antagonists.
Topics: Histamine; Histamine Antagonists; Promethazine; Pyrilamine | 1949 |
Spectrophotometric assay method for pyranisamine maleate.
Topics: Histamine; Maleates; Pyrilamine; Spectrophotometry | 1949 |
A comparative study of histamine activities on differentiation of osteoblasts and osteoclasts.
Topics: Alkaline Phosphatase; Animals; Bone Marrow Cells; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Differentiation; Cell Line; Cells, Cultured; Cimetidine; Core Binding Factor Alpha 1 Subunit; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Pyrilamine; RANK Ligand; Receptors, Histamine H1; Receptors, Histamine H2; RNA, Messenger; Transforming Growth Factor beta | 2007 |
Nerve growth factor enhances neurokinin A-induced airway responses and exhaled nitric oxide via a histamine-dependent mechanism.
Topics: Animals; Bronchial Hyperreactivity; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Lung Compliance; Male; Muscle Contraction; Muscle, Smooth; Nerve Growth Factor; Neurokinin A; Nitric Oxide; Pyrilamine; Receptors, Histamine; Respiratory Mechanics; Respiratory System; Trachea | 2008 |
Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats.
Topics: Animals; Anxiety; Behavior, Animal; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Microinjections; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Septum of Brain; Stereotaxic Techniques | 2008 |
Characterization of the effect of histamine on mouse corpus cavernosum.
Topics: Animals; Cimetidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Mice; Penile Erection; Penis; Pyrilamine | 2008 |
The synergistic effect of histamine and IL-6 on NGF secretion from cultured astrocytes is evoked by histamine stimulation of IL-6 secretion via H1-receptor-PKC-MAPK signalling pathway.
Topics: Animals; Astrocytes; Cells, Cultured; Enzyme Inhibitors; Histamine; Histamine Antagonists; Interleukin-6; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Protein Kinase C; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1 | 2008 |
Phosphatidylinositol 4,5-bisphosphate hydrolysis mediates histamine-induced KCNQ/M current inhibition.
Topics: Animals; Calcium; Cell Line; Cell Membrane; Estrenes; Histamine; Humans; Hydrolysis; Ion Channel Gating; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Neurons; Phosphatidylinositol 4,5-Diphosphate; Pyrilamine; Pyrrolidinones; Rats; Receptors, Histamine H1; Type C Phospholipases | 2008 |
GABA and histamine interaction in the basolateral amygdala of rats in the plus-maze test of anxiety-like behaviors.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; gamma-Aminobutyric Acid; Histamine; Histamine Agents; Male; Maze Learning; Microinjections; Muscimol; Pyrilamine; Rats; Rats, Wistar | 2008 |
[Role of histamine H(1) and H(2) receptors in the modulation of respiratory rhythmical discharge in medulla oblongata slice preparation of neonatal rats].
Topics: Animals; Animals, Newborn; Cimetidine; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hypoglossal Nerve; In Vitro Techniques; Male; Medulla Oblongata; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Histamine H2; Respiration | 2008 |
Modulatory effects of histamine on cat carotid body chemoreception.
Topics: Acetylcholine; Action Potentials; Animals; Carotid Body; Cats; Chemoreceptor Cells; Dose-Response Relationship, Drug; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H3 Antagonists; Hypoxia; In Vitro Techniques; Male; Microscopy, Immunoelectron; Nicotine; Nicotinic Agonists; Piperidines; Pyrilamine; Tyrosine 3-Monooxygenase | 2008 |
Aleudrine and anthisan in bronchial spasm.
Topics: Adrenal Glands; Bronchi; Bronchial Spasm; Histamine; Pyrilamine; Spasm; Tissue Extracts | 1948 |
Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.
Topics: Animals; Cell Count; Cimetidine; Cyclophosphamide; Cyclosporine; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ear Auricle; Eosinophil Peroxidase; Eosinophils; Gene Expression; Histamine; Histamine Antagonists; Immunoglobulin E; Interferon-gamma; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Picryl Chloride; Piperidines; Pyrilamine; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2009 |
Ameliorative effects of histamine on spatial memory deficits induced by scopolamine infusion into bilateral dorsal or ventral hippocampus as evaluated by the radial arm maze task.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Hippocampus; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Pyrilamine; Rats; Rats, Sprague-Dawley; Scopolamine; Spatial Behavior | 2009 |
Kujin suppresses histamine signaling at the transcriptional level in toluene 2,4-diisocyanate-sensitized rats.
Topics: Animals; Cytokines; Fabaceae; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Histidine Decarboxylase; Hypersensitivity; Male; Nasal Mucosa; Plant Roots; Pyrilamine; Rats; Rats, Inbred BN; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Th2 Cells; Toluene 2,4-Diisocyanate; Transcription, Genetic | 2009 |
Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions.
Topics: Allergens; Anaphylaxis; Animals; Arachis; Cholera Toxin; Cimetidine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hydroxyurea; Immunoglobulin E; Immunoglobulin G; Lipoxygenase Inhibitors; Mice; Mice, Inbred C57BL; Peanut Hypersensitivity; Platelet Membrane Glycoproteins; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine | 2009 |
Evidence for histamine as a new modulator of carotid body chemoreception.
Topics: Animals; Carotid Body; Cats; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Pyrilamine | 2009 |
Histamine induces human beta-defensin-3 production in human keratinocytes.
Topics: beta-Defensins; Blotting, Western; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Flavonoids; Histamine; Histamine H1 Antagonists; Humans; Infant, Newborn; Janus Kinase 2; Keratinocytes; Male; MAP Kinase Kinase Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyrilamine; Receptors, Histamine H1; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tyrosine; Tyrphostins; Up-Regulation | 2009 |
Anxiety-like behavior induced by histaminergic agents can be prevented by cannabinoidergic WIN55,212-2 injected into the dorsal hippocampus in mice.
Topics: Animals; Anxiety; Benzoxazines; Exploratory Behavior; Hippocampus; Histamine; Histamine Antagonists; Male; Mice; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Pyrilamine; Ranitidine | 2010 |
Effect of microinjection of histamine into the dorsal hippocampus on the orofacial formalin-induced pain in rats.
Topics: Analgesics; Animals; Behavior, Animal; Facial Pain; Formaldehyde; Hippocampus; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Injections, Subcutaneous; Lip; Male; Microinjections; Pain Measurement; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 2010 |
Involvement of histamine and histamine H2 receptors in nicotinamide-induced differentiation of human amniotic epithelial cells into insulin-producing cells.
Topics: Adult; Amniotic Fluid; C-Peptide; Cell Differentiation; Cells, Cultured; Cimetidine; Epithelial Cells; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Insulin; Insulin-Secreting Cells; Niacinamide; Nicotinic Agonists; Pregnancy; Pyrilamine; Receptors, Histamine H2 | 2010 |
Nitric oxide and histamine signal attempts to swallow: A component of learning that food is inedible in Aplysia.
Topics: Analysis of Variance; Animals; Aplysia; Association Learning; Deglutition; Electrophysiology; Enzyme Inhibitors; Feeding Behavior; Food; Histamine; Histamine H2 Antagonists; Learning; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oviposition; Physical Stimulation; Pyrilamine; S-Nitroso-N-Acetylpenicillamine | 2010 |
Withdrawal from repeated administration of morphine alters histamine-induced anxiogenic effects produced by intra-ventral hippocampal microinjection.
Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Hippocampus; Histamine; Histamine Antagonists; Imidazoles; Male; Microinjections; Morphine; Motor Activity; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Thiourea | 2010 |
Repeated histamine pretreatment decreased amnesia induced by post-training administration of the drug in a step-down inhibitory avoidance test in mice.
Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzazepines; Disease Models, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mice; Mice, Inbred Strains; Probability; Pyrilamine; Random Allocation; Statistics, Nonparametric; Sulpiride | 2010 |
The essential oil of Croton nepetaefolius selectively blocks histamine-augmented neuronal excitability in guinea-pig celiac ganglion.
Topics: Action Potentials; Animals; Croton Oil; Ganglia, Sympathetic; Ganglionic Blockers; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Male; Oils, Volatile; Pyrilamine | 2010 |
Histamine H(1) antagonist treatment with pyrilamine reduces nicotine self-administration in rats.
Topics: Animals; Butyrophenones; Drug Administration Schedule; Female; Follow-Up Studies; Food; Histamine; Histamine H1 Antagonists; Infusion Pumps; Injections; Motivation; Nicotine; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley; Self Administration; Tobacco Use Disorder | 2011 |
Activation of brain histaminergic neurotransmission: a mechanism for cognitive effects of memantine in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Brain; Brain-Derived Neurotrophic Factor; Calcium; Cognition; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Histamine; Humans; Male; Memantine; Methylhistamines; Mice; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2011 |
Histamine H(4) receptor antagonism inhibits allergen-specific T-cell responses mediated by human dendritic cells.
Topics: Adult; Allergens; Case-Control Studies; Dendritic Cells; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Indoles; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Piperazines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H4; T-Lymphocytes; Transcription, Genetic; Young Adult | 2011 |
Lipopolysaccharide induces H1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells.
Topics: Blotting, Western; Cells, Cultured; Coronary Vessels; Dinoprostone; Drug Synergism; Endothelial Cells; Epoprostenol; Flow Cytometry; Gene Expression; Histamine; Humans; Interleukin-6; Lipopolysaccharides; Pyrilamine; Radioligand Assay; Receptors, Histamine H1; Receptors, Histamine H2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Sulfonamides; Toll-Like Receptor 4; Tritium | 2011 |
Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Hippocampus; Histamine; Male; Morphine; Naloxone; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 2011 |
Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats.
Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Drug Interactions; Drug Therapy, Combination; Formaldehyde; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hyperalgesia; Male; Pain; Pain Perception; Peptide Fragments; Pyrilamine; Ranitidine; Rats; Rats, Wistar | 2011 |
Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Histamine; Histamine Agonists; Histamine H1 Antagonists; Imidazoles; Models, Molecular; Molecular Structure; Protein Binding; Pyrilamine; Receptors, Histamine H1; Structure-Activity Relationship | 2011 |
Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors.
Topics: Allergens; Animals; Benzazepines; Binding, Competitive; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Cell Line; CHO Cells; Cricetinae; Cricetulus; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Humans; In Vitro Techniques; Niacinamide; Ovalbumin; Phthalazines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Recombinant Proteins; Rhinitis, Allergic, Perennial; Transfection | 2011 |
Investigation on signal transduction pathways after H(1) receptor activated by histamine in C6 glioma cells: involvement of phosphatidylinositol and arachidonic acid metabolisms.
Topics: Animals; Arachidonic Acid; Calcium; Cell Line, Tumor; Egtazic Acid; Glioma; Glycosylphosphatidylinositols; Histamine; Phosphatidylinositols; Phospholipases A2; Pyrilamine; Rats; Receptors, Histamine H1; Signal Transduction | 2012 |
Influence of nitric oxide agents in the dorsal hippocampus of mice on anxiogenic-like effect induced by histamine.
Topics: Animals; Anxiety; Arginine; CA1 Region, Hippocampal; Enzyme Inhibitors; Hippocampus; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mice; Microinjections; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Pyrilamine; Ranitidine | 2012 |
Persistent histamine excitation of glutamatergic preoptic neurons.
Topics: Action Potentials; Animals; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glutamine; Histamine; Mice; Mice, Inbred C57BL; Neurons; Preoptic Area; Pyrilamine; Receptors, Histamine H1; RNA, Messenger; Signal Transduction; Triprolidine; TRPC Cation Channels; Type C Phospholipases; Vesicular Glutamate Transport Protein 2 | 2012 |
On the role of histamine receptors in regulating pigmentary responses in Oreochromis mossambicus melanophores.
Topics: Animals; Female; Histamine; Histamine Agonists; Histamine Antagonists; Male; Melanins; Melanophores; p-Methoxy-N-methylphenethylamine; Pigments, Biological; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Tilapia | 2012 |
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol Phosphates; Pyrilamine; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 2013 |
Punishing and cardiovascular effects of intravenous histamine in rats: pharmacological selectivity.
Topics: Animals; Cardiovascular System; Conditioning, Operant; Dose-Response Relationship, Drug; Heart Rate; Histamine; Histamine Antagonists; Injections, Intravenous; Ketotifen; Male; Punishment; Pyrilamine; Ranitidine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology | 2013 |
Vasopeptidase-activated latent ligands of the histamine receptor-1.
Topics: Animals; Arrestins; beta-Arrestins; Bradykinin; Cetirizine; CHO Cells; Cricetulus; HEK293 Cells; Histamine; Histamine Antagonists; Humans; In Vitro Techniques; Ligands; Peptide Hydrolases; Peptides; Prodrugs; Pyrilamine; Radioligand Assay; Receptor, Bradykinin B2; Receptors, Histamine H1; Umbilical Veins; Vasoconstriction | 2013 |
Infralimbic cortex controls core body temperature in a histamine dependent manner.
Topics: Adrenergic beta-Antagonists; Animals; Arousal; Body Temperature; Body Temperature Regulation; Frontal Lobe; Histamine; Histamine H1 Antagonists; Male; Motor Activity; Picrotoxin; Propranolol; Pyrilamine; Rats; Rats, Sprague-Dawley | 2014 |
Histaminergic modulation of cholinergic release from the nucleus basalis magnocellularis into insular cortex during taste aversive memory formation.
Topics: Acetylcholine; Animals; Avoidance Learning; Basal Nucleus of Meynert; Cerebral Cortex; Conditioning, Classical; Histamine; Male; Memory; Microdialysis; Microscopy, Confocal; Microscopy, Fluorescence; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, GABA; Taste; Taste Perception | 2014 |
Antihistamine from Tragia involucrata L. leaves.
Topics: Animals; Bronchoconstriction; Euphorbiaceae; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; India; Muscle Contraction; Muscle Relaxation; Plant Extracts; Plant Leaves; Pyrilamine | 2015 |
Histamine resets the circadian clock in the suprachiasmatic nucleus through the H1R-CaV 1.3-RyR pathway in the mouse.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Circadian Clocks; Dantrolene; Histamine; Histamine H1 Antagonists; Male; Mice; Mice, Inbred C57BL; Nimodipine; Pyrilamine; Receptors, Histamine H1; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Suprachiasmatic Nucleus | 2015 |
Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis.
Topics: Acute Disease; Animals; Apoptosis; Cell Line; Cimetidine; Creatine Kinase, MB Form; Disease Models, Animal; Heart Injuries; Histamine; Histidine Decarboxylase; Humans; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardial Infarction; Myocytes, Cardiac; Promoter Regions, Genetic; Pyrilamine | 2015 |
TRPA1, substance P, histamine and 5-hydroxytryptamine interact in an interdependent way to induce nociception.
Topics: Acetanilides; Animals; Histamine; Histamine H1 Antagonists; Isothiocyanates; Male; Oligonucleotides, Antisense; p-Methoxy-N-methylphenethylamine; Pain; Piperazines; Purines; Pyrilamine; Quinuclidines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Histamine H1; Receptors, Neurokinin-1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Substance P; TRPA1 Cation Channel; TRPC Cation Channels | 2017 |
The histaminergic system is involved in psychological stress-induced hyperthermia in rats.
Topics: Animals; Body Temperature Regulation; Cimetidine; Fever; Histamine; Histamine Agonists; Imidazoles; Male; Pyrilamine; Rats; Rats, Wistar; Stress, Physiological | 2017 |
Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells.
Topics: Calcium; Cell Line; Gene Expression Regulation; Gene Silencing; Histamine; Humans; Indoles; Interleukin-1beta; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mast Cells; Methylhistamines; Piperazines; Pyrilamine; Receptors, Histamine H4; RNA, Small Interfering | 2018 |
Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
Topics: Animals; Cyproheptadine; Histamine; Histamine Agonists; Histamine Antagonists; Mucous Membrane; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Terfenadine; Urinary Bladder; Urothelium | 2019 |
Inonotus obliquus attenuates histamine-induced microvascular inflammation.
Topics: Agaricales; Animals; Arterioles; Basidiomycota; Endothelium, Vascular; Histamine; Inflammation; Intercellular Junctions; Male; Mast Cells; Mice; Mice, Inbred C57BL; Microvessels; Pyrilamine; Vasodilation | 2019 |
Histamine receptors mediate contraction of reticular groove smooth muscle of adult goats.
Topics: Animals; Blotting, Western; Cimetidine; Cyproheptadine; Dose-Response Relationship, Drug; Goats; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Immunohistochemistry; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine; Stomach, Ruminant | 2020 |
Neurotransmitters of sleep and wakefulness in flatworms.
Topics: Acetylcholine; Adenosine; Animals; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Mammals; Neurotransmitter Agents; Platyhelminths; Pyrilamine; Serotonin; Sleep; Wakefulness | 2022 |