pyrilamine has been researched along with fpl 55712 in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (70.59) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ando, M; Araki, S; Honda, I; Kawano, O; Kohrogi, H; Sugimoto, M; Yamaguchi, T | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
| del Balzo, U; Levi, R; Sakuma, I | 1 |
| Ishii, A; Miyamoto, T; Mizushima, Y; Motoishi, M; Nakagawa, T; Nambu, F; Shida, T; Yui, Y | 1 |
| Hayashi, H; Watanabe, A | 1 |
| Regal, JF | 1 |
| Creese, BR; Temple, DM | 1 |
| Hirao, T; Kohno, H; Konno-Amano, S; Mori, H; Sato, Y | 1 |
| Bertrand, C; Landry, Y; Tschirhart, E | 1 |
| Desquand, S; Lefort, J; Liu, FT; Mencia-Huerta, JM; Vargaftig, BB | 1 |
| Charette, L; Denis, D; Jones, TR | 1 |
| Cordeiro, R; Garcez Do Carmo, L; Lagente, V; Lefort, J; Randon, J; Vargaftig, BB | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD | 1 |
| Conder, GA; Elfring, G; Griffin, RL; Oostveen, JA; Richards, IM | 1 |
| Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Bell, RL; Regal, JF | 1 |
| Jones, TR; Masson, P | 1 |
| Hirasawa, N; Ohuchi, K; Tsurufuji, S; Watanabe, M | 1 |
| Cade, JF; Clancy, RL; Pain, MC; Walker, SE | 1 |
| Chand, N; DeRoth, L | 1 |
| Wasserman, MA; Weichman, BM; Woodward, DF | 1 |
| Hugli, TE; Marceau, F | 1 |
| Bloor, CM; Erickson, BW; Huey, R; Hugli, TE | 1 |
| Bloor, CM; Huey, R; Hugli, TE | 1 |
| Alphin, RS; Callaham, EM; Foxwell, MH; Smith, WL; Yanni, JM | 1 |
| Ottenhof, M; Ufkes, JG | 1 |
| Bemis, KG; Fleisch, JH; Rinkema, LE | 1 |
| Asakura, K; Narita, S | 1 |
| Aishita, H; Furuya, T; Kobayashi, T; Muryobayashi, K; Nakagawa, N; Nambu, F; Obata, T; Okada, Y; Sawada, M; Terawaki, T | 1 |
| Takami, M; Tsukada, W | 1 |
1 trial(s) available for pyrilamine and fpl 55712
| Article | Year |
|---|---|
Effect of leukotriene antagonist on experimental and clinical bronchial asthma.
Topics: Allergens; Anaphylaxis; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Chromones; Drug Evaluation; Drug Evaluation, Preclinical; Dust; Guinea Pigs; Histamine; Humans; Immunization, Passive; Indomethacin; Male; Ovalbumin; Pyrilamine; SRS-A | 1991 |
33 other study(ies) available for pyrilamine and fpl 55712
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A novel leukotriene antagonist, ONO-1078, inhibits and reverses human bronchial contraction induced by leukotrienes C4 and D4 and antigen in vitro.
Topics: Antigens; Bronchi; Bronchoconstriction; Chromones; Female; Humans; In Vitro Techniques; Male; Pyrilamine; SRS-A | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
Cardiac dysfunction caused by recombinant human C5A anaphylatoxin: mediation by histamine, adenosine and cyclooxygenase arachidonate metabolites.
Topics: Adenosine; Animals; Chromones; Complement Activation; Complement C3a; Complement C5a; Guinea Pigs; Heart; Histamine Release; Male; Myocardial Contraction; Pyrilamine; Recombinant Proteins; Thromboxanes | 1990 |
Allergen-induced biphasic bronchoconstriction in rats.
Topics: Airway Resistance; Allergens; Aminophylline; Animals; Bronchial Spasm; Chromones; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Histamine; Hypersensitivity; Leukotrienes; Male; Methacrylates; Methysergide; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; Thromboxane B2; Time Factors | 1990 |
IgG vs IgE: mediators of antigen-induced guinea pig lung parenchymal contraction.
Topics: Animals; Antigens; Atropine; Chromones; Guinea Pigs; Histamine Release; Immunoglobulin E; Immunoglobulin G; Indomethacin; Lung; Male; Muscle Contraction; Pyrilamine; SRS-A | 1985 |
Anaphylactic responses of guinea-pig lung parenchymal strips: antigen concentration dependence and pharmacological modification.
Topics: Anaphylaxis; Animals; Antigens; Chromones; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Lung; Ovalbumin; Pyrilamine | 1986 |
Passive air-pouch anaphylaxis in rats. II. Pharmacological characterization.
Topics: Adult; Air; Anaphylaxis; Animals; Capillary Permeability; Chromones; Cromolyn Sodium; Dexamethasone; Dinoprostone; Exudates and Transudates; Histamine Release; Humans; Immunization, Passive; Indomethacin; Isoproterenol; Ketotifen; Masoprocol; Models, Biological; ortho-Aminobenzoates; Pyrilamine; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Nedocromil sodium inhibits IgE- and IgG-related antigen-induced contraction in guinea-pig trachea.
Topics: Airway Resistance; Anaphylaxis; Animals; Benzoquinones; Chromones; Cromolyn Sodium; Flavonols; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Male; Nedocromil; Ovalbumin; Pyrilamine; Quercetin; Quinolones; Quinones; Trachea | 1989 |
Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies.
Topics: Animals; Blood Cell Count; Bronchial Spasm; Chromones; Dinitrophenols; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunization, Passive; Immunoglobulin E; Lactones; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin, Bovine; SRS-A | 1989 |
Leukotriene and anti-IgE induced contractions of human isolated trachea: studies with leukotriene receptor antagonists and a novel 5-lipoxygenase inhibitor.
Topics: Animals; Antibodies, Anti-Idiotypic; Arachidonate Lipoxygenases; Atropine; Benzofurans; Chromones; Goats; Humans; In Vitro Techniques; Indomethacin; Keto Acids; Lipoxygenase Inhibitors; Muscle Contraction; Phenylbutyrates; Pyrilamine; Receptors, Leukotriene; Receptors, Prostaglandin; SRS-A; Sulfones; Trachea | 1988 |
Failure of a combined anti-histamine and anti-leukotriene treatment to suppress passive anaphylaxis in the guinea-pig.
Topics: Anaphylaxis; Animals; Aspirin; Chromones; Female; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Lung; Male; Muscle Contraction; Ovalbumin; Propranolol; Pyrilamine; SRS-A | 1986 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Male; Methysergide; Phthalazines; Pyridazines; Pyrilamine; SRS-A | 1986 |
Role of cyclooxygenase products of arachidonic acid metabolism in Ascaris antigen-induced bronchoconstriction in sensitized dogs.
Topics: Animals; Antigens, Helminth; Arachidonic Acids; Ascaris; Blood Pressure; Chromones; Dogs; Epoprostenol; Heart Rate; Histamine; Indomethacin; Lung; Lung Volume Measurements; Male; Prostaglandin-Endoperoxide Synthases; Pyrilamine; Respiration; SRS-A | 1988 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Mediators of C5a-induced bronchoconstriction in the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A | 1987 |
Comparative study of the pulmonary effects of intravenous leukotrienes and other bronchoconstrictors in anaesthetized guinea pigs.
Topics: Airway Resistance; Anesthesia; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Blood Pressure; Bronchi; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium Compounds; Histamine; Indomethacin; Lung; Male; Methysergide; Prostaglandin Endoperoxides, Synthetic; Pyrilamine; SRS-A; Timolol; Vagotomy | 1985 |
Pharmacological analysis of the vascular permeability response in the anaphylactic phase of allergic inflammation in rats.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromones; Dexamethasone; Histamine; Indomethacin; Inflammation; Kinetics; Male; Methysergide; Prostaglandins; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A | 1985 |
Slow-reacting substance from alveolar macrophages--a mechanism of asthma?
Topics: Animals; Asthma; Atropine; Autacoids; Chromones; Cimetidine; Ethers; Guinea Pigs; Indomethacin; Macrophages; Methysergide; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1981 |
Acute systemic anaphylaxis in adult domestic fowl: evidence for the protective role of H2-histaminergic and beta 2-adrenergic receptors.
Topics: Anaphylaxis; Animals; Blood Pressure; Carotid Arteries; Chickens; Chromones; Cimetidine; Dimaprit; Ethers; Heart Rate; Metiamide; Poultry Diseases; Propranolol; Pyrilamine; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Histamine; Receptors, Histamine H2; Terbutaline; Thiourea | 1980 |
Investigation of leukotriene involvement in the vasopermeability response associated with guinea pig tracheal anaphylaxis: comparison with cutaneous anaphylaxis.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromium Radioisotopes; Chromones; Female; Guinea Pigs; Histamine; In Vitro Techniques; Leukotriene E4; Ovalbumin; Passive Cutaneous Anaphylaxis; Pyrilamine; SRS-A; Time Factors; Trachea | 1983 |
Effect of C3a and C5a anaphylatoxins on guinea-pig isolated blood vessels.
Topics: Anaphylatoxins; Animals; Aspirin; Blood Vessels; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemolysis; Histamine; Indomethacin; Male; Muscle Contraction; Norepinephrine; Peptides; Pyrilamine; Tachyphylaxis | 1984 |
Contraction of guinea pig lung by synthetic oligopeptides related to human C3a.
Topics: Acetylcholine; Animals; Chromones; Complement C3; Complement C3a; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Muscle Contraction; Oligopeptides; Pyrilamine; SRS-A; Tachyphylaxis | 1984 |
Effects of human anaphylatoxins on guinea pig atria.
Topics: Alprostadil; Anaphylatoxins; Animals; Chromones; Complement C3; Complement C3a; Complement C5; Complement C5a; Guinea Pigs; Heart Rate; Histamine; Humans; In Vitro Techniques; Indomethacin; Myocardial Contraction; Peptides; Prostaglandins E; Pyrilamine | 1984 |
A method for measuring changes in tracheal mucus gel layer thickness as an indication of an immediate hypersensitivity response.
Topics: Acetylcysteine; Aluminum Hydroxide; Animals; Atropine; Chromones; Cimetidine; Cromolyn Sodium; Dose-Response Relationship, Immunologic; Expectorants; Hypersensitivity, Immediate; Immune Sera; Methods; Methysergide; Mucus; Ovalbumin; Pyrilamine; Rats; Rats, Inbred Strains; Trachea | 1984 |
Characterization of various antiallergic agents using a new method for inducing systemic anaphylaxis in the rat.
Topics: Anaphylaxis; Animals; Blood Pressure; Bronchodilator Agents; Chromones; Cromolyn Sodium; Disease Models, Animal; Female; Hemodynamics; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Prednisolone; Pyrilamine; Rats; Rats, Inbred BN | 1984 |
Production and antagonism of cutaneous vascular permeability in the guinea pig in response to histamine, leukotrienes and A23187.
Topics: Animals; Bradykinin; Calcimycin; Capillary Permeability; Chromones; Guinea Pigs; Histamine; Indomethacin; Injections, Intradermal; Male; Pyrilamine; Receptors, Histamine; Skin; SRS-A | 1984 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchodilator Agents; Chromones; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Immunization; Male; Ovalbumin; Phthalazines; Pulmonary Eosinophilia; Pyrilamine; SRS-A | 1993 |
In vitro effect of DP-1904, a novel anti-asthma agent, against antigen-induced constriction and TXB2 release from the isolated guinea-pig lung parenchymal tissue.
Topics: Animals; Anti-Asthmatic Agents; Antigens; Benzoquinones; Bronchoconstriction; Chromones; Enzyme Inhibitors; Guinea Pigs; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Lung; Male; Pyrilamine; Tetrahydronaphthalenes; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase | 1998 |