pyrilamine has been researched along with doxepin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (22.22) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| de Esch, IJ; de Graaf, C; Iwata, S; Katritch, V; Kooistra, AJ; Kuijer, M; Leurs, R; Shimamura, T; Shiroishi, M; Stevens, RC; Vischer, HF | 1 |
| Bortolato, A; Bosma, R; de Esch, IJ; de Graaf, C; Kooistra, AJ; Kuhne, S; Leurs, R; Mason, JS; Vischer, HF; Wijtmans, M | 1 |
| Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Meguro, K; Takahashi, T; Watanabe, T; Yanai, K; Yokoyama, H | 1 |
| Almeida, L; Figueiredo, A; Gonçalo, M; Poiares-Baptista, A; Ribeiro, CA; Teixeira, F | 1 |
| Hatano, K; Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Matsuzawa, T; Nunoki, K; Watanabe, T; Yanai, K | 1 |
| Aceves, J; Mariscal, S; Morrison, KE; Young, JM | 1 |
| Richelson, E; Taylor, JE | 1 |
| Hatazawa, J; Ido, T; Ishiwata, K; Itoh, M; Iwata, R; Takahashi, T; Watabe, K; Watanabe, T; Yanai, K | 1 |
| Inoue, I; Kitamura, D; Kobayashi, T; Niimura, K; Taniuchi, I; Watanabe, T; Yanai, K | 1 |
| Arima, T; Kitamura, Y; Kitayama, Y; Nomura, Y | 1 |
| Itoh, M; Okamura, N; Tagawa, M; Watanabe, T; Yanai, K | 1 |
| Carlson, BB; Salamone, JD; Trevitt, JT | 1 |
1 review(s) available for pyrilamine and doxepin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
1 trial(s) available for pyrilamine and doxepin
| Article | Year |
|---|---|
Analysis of plasma metabolites during human PET-studies with three receptor ligands, [11C]YM-09151-2, [11C]doxepin and [11C]pyrilamine.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Benzamides; Biotransformation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dopamine Antagonists; Doxepin; Female; Histamine H1 Antagonists; Humans; Injections, Intravenous; Male; Middle Aged; Protein Binding; Pyrilamine; Receptors, Dopamine D2; Receptors, Histamine H1; Tomography, Emission-Computed | 1996 |
16 other study(ies) available for pyrilamine and doxepin
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor.
Topics: Databases, Factual; HEK293 Cells; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Histamine H1 | 2011 |
Identification of Ligand Binding Hot Spots of the Histamine H
Topics: Amines; Binding Sites; Crystallography, X-Ray; Drug Design; HEK293 Cells; Humans; Ligands; Models, Molecular; Protein Binding; Receptors, Histamine H1; Small Molecule Libraries; Structure-Activity Relationship | 2016 |
Histamine H1 receptors in human brain visualized in vivo by [11C]doxepin and positron emission tomography.
Topics: Adult; Brain; Carbon Isotopes; Chlorpheniramine; Doxepin; Humans; Injections, Intravenous; Male; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed | 1992 |
Mechanism of action of doxepin in the treatment of chronic urticaria.
Topics: Adult; Aged; Animals; Atropine; Carbachol; Chronic Disease; Dimaprit; Doxepin; Female; Gastric Juice; Guinea Pigs; Heart; Histamine; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pylorus; Pyrilamine; Rats; Thiourea; Urticaria | 1990 |
Visualization of histamine H1 receptors in dog brain by positron emission tomography.
Topics: Animals; Brain; Dogs; Doxepin; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed; Triprolidine | 1990 |
The binding of doxepin to histamine H1-receptors in guinea-pig and rat brain.
Topics: Animals; Binding, Competitive; Brain; Cerebral Cortex; Doxepin; Female; Guinea Pigs; In Vitro Techniques; Intestines; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1 | 1985 |
High-affinity binding of [3H]doxepin to histamine H1-receptors in rat brain: possible identification of a subclass of histamine H1-receptors.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Doxepin; Histamine; In Vitro Techniques; Kinetics; Membranes; Pyrilamine; Rats; Receptors, Histamine; Receptors, Histamine H1 | 1982 |
Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors.
Topics: Animals; Base Sequence; Brain; Circadian Rhythm; Darkness; DNA Primers; Doxepin; Exploratory Behavior; Genomic Library; Heterozygote; Homozygote; Light; Mice; Mice, Knockout; Mice, Neurologic Mutants; Motor Activity; Polymerase Chain Reaction; Pyrilamine; Receptors, Histamine H1; Reference Values; Restriction Mapping | 1996 |
Regulation of [Ca2+]i rise activated by doxepin-sensitive H1-histamine receptors in Jurkat cells, cloned human T lymphocytes.
Topics: Animals; Blotting, Northern; Blotting, Western; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Doxepin; GTP-Binding Proteins; Histamine; Humans; Proto-Oncogene Proteins c-fos; Pyrilamine; Rats; Receptors, Histamine H1; T-Lymphocytes | 1996 |
New findings in pharmacological effects induced by antihistamines: from PET studies to knock-out mice.
Topics: Animals; Behavior, Animal; Brain; Cognition Disorders; Doxepin; Histamine Antagonists; Humans; Male; Mice; Mice, Knockout; Pyrilamine; Receptors, Histamine H1; Tomography, Emission-Computed | 1999 |
Effects of H1 antagonists on cholinomimetic-induced tremulous jaw movements: studies of diphenhydramine, doxepin, and mepyramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Cholinergic Agents; Clozapine; Diphenhydramine; Dose-Response Relationship, Drug; Doxepin; Histamine H1 Antagonists; Jaw; Male; Movement; Olanzapine; Pirenzepine; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Muscarinic; Tacrine; Tremor | 2000 |