pyrilamine has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (36.17) | 18.7374 |
| 1990's | 27 (57.45) | 18.2507 |
| 2000's | 2 (4.26) | 29.6817 |
| 2010's | 1 (2.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Ito, Y; Tashiro, K; Xie, Z | 1 |
| Hibi, M; Iwama, T; Sakashita, M; Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Corfield, DR; Webber, SE; Widdicombe, JG | 1 |
| Coyle, AJ; Lefort, J; Vargaftig, BB | 1 |
| Ahmad, Z; Baumann, G; Berdel, WE; Felix, SB; Hashemi, T; Niemczyk, M | 1 |
| Braquet, P; Carrier, J; Jancar, S; Sirois, MG; Sirois, P | 1 |
| Bureau, M; Dry, J; Lefort, J; Vargaftig, BB; Vincent, D | 1 |
| Harada, K; Katayama, K; Katayama, S; Muramoto, K; Sakuma, Y; Tsunoda, H | 1 |
| Imanishi, N; Morooka, S; Sugasawa, T; Uchida, M | 1 |
| Heuer, HO | 2 |
| Krell, RD; McCarthy, M | 1 |
| Lefort, J; Lellouch-Tubiana, A; Terlain, B; Vannier, E; Vargaftig, BB | 1 |
| Barnes, PJ; Belvisi, MG; Stretton, CD | 1 |
| Northover, AM | 1 |
| Conklyn, M; Showell, HJ; Watson, JW | 1 |
| Durham, SK; Selig, WM; Tocker, JE; Welton, AF | 1 |
| Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE | 1 |
| Hayashi, M; Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
| Fjellner, B; Hägermark, O | 1 |
| Bralet, J; Rochette, L; Tannière-Zeller, M | 1 |
| Braquet, P; Chabrier, PE; Lagente, V; Mencia-Huerta, JM | 1 |
| Casals-Stenzel, J; Heuer, H | 1 |
| Desquand, S; Lefort, J; Liu, FT; Mencia-Huerta, JM; Vargaftig, BB | 1 |
| Aharony, D; Redkar-Brown, DG | 1 |
| Archer, CB; MacDonald, DM; Morley, J; Page, CP; Paul, W; Sanjar, S | 1 |
| Borgeat, P; Braquet, P; Etienne, A; Sirois, P; Touvay, C; Vilain, B | 1 |
| Cirino, M; Desquand, S; Lagente, V; Lefort, J; Vargaftig, BB | 1 |
| Aihara, H; Hongoh, K; Kurachi, M; Watanabe, A | 1 |
| Hayashi, M; Oh, S; Yamaki, K | 1 |
| Knee, CD; Krell, RD; Kusner, EJ | 1 |
| Lefort, J; Lellouch-Tubiana, A; Pfister, A; Vargaftig, BB | 1 |
| Casals-Stenzel, J | 1 |
| Braquet, P; Desquand, S; Lagente, V; Lefort, J; Randon, J; Touvay, C; Vargaftig, BB; Vilain, B | 1 |
| Benveniste, J; Bonnet, J; Page, CP; Paul, W; Pfister, A; Pirotzky, E; Roubin, R | 1 |
| Chignard, M; Lefort, J; Medeiros, MC; Vargaftig, BB; Wal, F | 1 |
| Davison, JS; Mathison, R | 1 |
| Langer, JC; Liebman, SM; Monk, PK; Pelletier, GJ | 1 |
| Asakura, K; Narita, S | 1 |
| Naraba, H; Oh-ishi, S; Tokumasu, T; Ueno, A | 1 |
| Akiyama, K; Maeda, Y; Mita, H; Saito, H; Shimizu, H | 1 |
| Balsa, D; Ferrando, R; Forn, J; García-Rafanell, J; Giral, M; Merlos, M; Puigdemont, A; Queralt, M | 1 |
| Guo, ZG; Zeng, S | 1 |
| Takami, M; Tsukada, W | 1 |
| Bardhan, KD; Brown, NJ; Jacob, S; Kalia, N; Reed, MW | 1 |
| Dessaint, JP; Devos, P; Dussart, P; Dutoit, V; El Behi, M; Lefranc, D; Prin, L; Vermersch, P; Zéphir, H | 1 |
1 trial(s) available for pyrilamine and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Experimental pruritus evoked by platelet activating factor (PAF-acether) in human skin.
Topics: Adult; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Female; Histamine; Humans; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Pruritus; Pyrilamine; Skin | 1985 |
46 other study(ies) available for pyrilamine and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Effects of PAF on excitatory neuro-effector transmission in dog airways.
Topics: Acetylcholine; Animals; Benzoquinones; Bronchi; Carbachol; Dogs; Electric Stimulation; Female; In Vitro Techniques; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Synaptic Transmission; Trachea | 1992 |
Inhibitory effect of NZ-107 on anaphylactic bronchoconstriction in guinea pigs and rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Anaphylaxis; Animals; Bronchoconstriction; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Indomethacin; Injections, Intravenous; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Prostaglandin Endoperoxides, Synthetic; Pyridazines; Pyrilamine; Rats; Rats, Inbred Strains; Regression Analysis; SRS-A | 1992 |
Mechanisms of platelet activating factor-induced changes in sheep tracheal blood flow.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Chromones; Cimetidine; Dose-Response Relationship, Drug; Female; Indomethacin; Methacholine Compounds; Muscle Tonus; Muscle, Smooth; Nedocromil; Platelet Activating Factor; Pyrilamine; Quinolones; Regional Blood Flow; Sheep; Trachea; Triazoles; Vascular Resistance | 1991 |
The effect of cetirizine on antigen-dependent leucopenia in the guinea-pig.
Topics: Animals; Benzeneacetamides; Benzhydryl Compounds; Blood Platelets; Cetirizine; Female; Guinea Pigs; Histamine H1 Antagonists; Hydroxamic Acids; Hydroxyzine; In Vitro Techniques; Leukocyte Count; Leukopenia; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrilamine; Terfenadine | 1991 |
Characterization of cardiovascular events mediated by platelet activating factor during systemic anaphylaxis.
Topics: Anaphylaxis; Animals; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Output; Cimetidine; Electrocardiography; Female; Guinea Pigs; Heart Rate; Hemodynamics; Histamine; Male; Myocardial Contraction; Ovalbumin; Platelet Activating Factor; Pyrilamine; Triazoles | 1990 |
PAF induces rat plasma extravasation and releases eicosanoids during anaphylaxis.
Topics: Anaphylaxis; Animals; Blood Proteins; Capillary Permeability; Diterpenes; Eicosanoids; Ginkgolides; Indomethacin; Lactones; Male; Methysergide; Peritoneal Cavity; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains | 1991 |
Dissociation between LPS-induced bronchial hyperreactivity and airway edema in the guinea-pig.
Topics: Animals; Aspirin; Azepines; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Escherichia coli; Guinea Pigs; Lipopolysaccharides; Macrophages; Male; Neutrophils; Platelet Activating Factor; Pulmonary Edema; Pyrilamine; Respiratory Hypersensitivity; Triazoles | 1991 |
Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice.
Topics: Administration, Inhalation; Anaphylaxis; Animals; Antigens; Asthma; Azepines; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; Triazoles | 1991 |
Effect of the selective PAF antagonist SM-10661 on an asthmatic model. 1. Effect on passive anaphylactic bronchoconstriction in guinea pigs.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Ovalbumin; Platelet Activating Factor; Propranolol; Pyrilamine; SRS-A; Thiazoles; Thiazolidines | 1991 |
Effect of the hetrazepinoic platelet-activating factor antagonist Bepafant (WEB 2170) in models of active and passive anaphylaxis in mice and guinea pigs.
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Lung; Male; Mice; Mice, Inbred Strains; Ovalbumin; Passive Cutaneous Anaphylaxis; Platelet Activating Factor; Propranolol; Pyrilamine; Respiration; Triazoles | 1991 |
Pharmacologic analysis of platelet activating factor16- and 18-induced bronchoconstriction in the guinea pig.
Topics: Animals; Atropine; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Leukocyte Count; Lung; Male; Methysergide; Platelet Activating Factor; Platelet Count; Propranolol; Pyrilamine; Respiratory Function Tests; Thiorphan | 1991 |
Inhibition of active anaphylaxis in mice and guinea pigs by the new hetrazepinoic PAF antagonist bepafant (WEB 2170).
Topics: Anaphylaxis; Animals; Azepines; Blood Pressure; Bronchoconstriction; Guinea Pigs; Immunization; Male; Mice; Ovalbumin; Platelet Activating Factor; Propranolol; Pulmonary Ventilation; Pyrilamine; Triazoles | 1991 |
Lipopolysaccharide from Escherichia coli reduces antigen-induced bronchoconstriction in actively sensitized guinea pigs.
Topics: Animals; Antigens; Aspirin; Bronchoconstriction; Cell Degranulation; Endotoxins; Escherichia coli; Guinea Pigs; Hemodynamics; Histamine; Hypersensitivity; Leukopenia; Lipopolysaccharides; Mast Cells; Microscopy, Electron; N-Formylmethionine Leucyl-Phenylalanine; Ovalbumin; Platelet Activating Factor; Pyrilamine; Thromboxane B2 | 1991 |
Bombesin-induced bronchoconstriction in the guinea pig: mode of action.
Topics: Animals; Azepines; Blood Pressure; Bombesin; Bronchoconstriction; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Muscle, Smooth; Platelet Activating Factor; Pyrilamine; Trachea; Triazoles | 1991 |
Modification by some antagonists of the shape changes of venous endothelial cells in response to inflammatory agents in vitro.
Topics: Aminoquinolines; Animals; Bradykinin; Calcimycin; Calcium; Cimetidine; Endothelium, Vascular; Guinea Pigs; Histamine; Histamine Antagonists; Isoproterenol; Platelet Activating Factor; Pyrilamine; Vena Cava, Inferior | 1990 |
IgG1-mediated acute pulmonary hypersensitivity response in the guinea pig. Involvement of specific lipid mediators.
Topics: Acute Disease; Animals; Azepines; Bronchoconstriction; Dicarboxylic Acids; Dose-Response Relationship, Drug; Furans; Guinea Pigs; Immunization; Immunoglobulin G; Indoles; Lipids; Lung; Male; Ovalbumin; Phenylcarbamates; Piroxicam; Platelet Activating Factor; Propranolol; Pyrilamine; Respiratory Hypersensitivity; SRS-A; Sulfonamides; Tosyl Compounds; Triazoles | 1990 |
Phospholipase A2-induced pulmonary and hemodynamic responses in the guinea pig. Effects of enzyme inhibitors and mediators antagonists.
Topics: Animals; Azepines; Blood Pressure; Bronchi; Bronchoalveolar Lavage Fluid; Dexamethasone; Enzyme Inhibitors; Guinea Pigs; Humans; Indazoles; Indomethacin; Lung; Male; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pressure; Propranolol; Pyrilamine; SRS-A; Trachea; Triazoles | 1990 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats | 1990 |
Assessment of vascular permeability increase in the mouse by dye leakage during paw edema.
Topics: Animals; Bradykinin; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Edema; Foot; Histamine; Male; Mice; Mice, Inbred ICR; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Tetradecanoylphorbol Acetate | 1990 |
PAF-acether-induced mortality in mice: protection by benzodiazepines.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Benzodiazepines; Cattle; Death; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Mice; Plant Extracts; Platelet Activating Factor; Pyrilamine; Triazoles | 1989 |
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig.
Topics: Aerosols; Animals; Blood Pressure; Bronchi; Diterpenes; Endothelins; Endothelium, Vascular; Ginkgolides; Guinea Pigs; Indomethacin; Lactones; Male; Nifedipine; Peptides; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Verapamil | 1989 |
The pathophysiological role of PAF in anaphylactic lung reaction in the guinea pig and in endotoxin shock evidenced by the specific PAF-antagonist WEB 2086.
Topics: Anaphylaxis; Animals; Antigens; Azepines; Disease Models, Animal; Endotoxins; Escherichia coli; Guinea Pigs; Lung Diseases; Ovalbumin; Platelet Activating Factor; Pyrilamine; Shock, Septic; Triazines; Triazoles | 1989 |
Antigen-induced bronchopulmonary alterations in the guinea pig: a new model of passive sensitization mediated by mouse IgE antibodies.
Topics: Animals; Blood Cell Count; Bronchial Spasm; Chromones; Dinitrophenols; Diterpenes; Female; Ginkgolides; Guinea Pigs; Immunization, Passive; Immunoglobulin E; Lactones; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin, Bovine; SRS-A | 1989 |
Inhibition of antigen-induced contraction of guinea pig trachea by ICI 198,615.
Topics: Animals; Antigens; Guinea Pigs; In Vitro Techniques; Indazoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phospholipid Ethers; Platelet Activating Factor; Pyrazoles; Pyrilamine; SRS-A; Trachea | 1989 |
Effects of serum albumin, indomethacin and histamine H1-antagonists on Paf-acether-induced inflammatory responses in the skin of experimental animals and man.
Topics: Adult; Animals; Blood Proteins; Chlorpheniramine; Guinea Pigs; Histamine H1 Antagonists; Humans; Indomethacin; Inflammation; Male; Platelet Activating Factor; Pyrilamine; Serum Albumin; Skin | 1985 |
Characterization of platelet activating factor (PAF)-acether-induced contractions of guinea-pig lung strips by selected inhibitors of arachidonic acid metabolism and by PAF-acether antagonists.
Topics: Animals; Aspirin; Benzofurans; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; Histamine; Imidazoles; Lactones; Leukotriene B4; Lignans; Lung; Male; Methacrylates; Muscle Contraction; Muscle, Smooth; Plant Extracts; Platelet Activating Factor; Prostaglandin Antagonists; Pyrilamine; SRS-A | 1986 |
Involvement of PAF-acether in anaphylactic bronchoconstriction induced in guinea pigs by aerosolized antigen.
Topics: Aerosols; Anaphylaxis; Animals; Antigens; Bronchial Spasm; Chromones; Desensitization, Immunologic; Female; Guinea Pigs; Histamine; Male; Ovalbumin; Platelet Activating Factor; Pyrilamine; Time Factors | 1988 |
Suppression of bronchial response to platelet activating factor following taurine administration.
Topics: Animals; Bronchial Spasm; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats; Rats, Inbred Strains; Serotonin; SRS-A; Taurine | 1987 |
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; Indomethacin; Inflammation; Injections; Leukocyte Count; Male; Methysergide; Phospholipid Ethers; Platelet Activating Factor; Pleural Effusion; Pleurisy; Prostaglandins; Pyrilamine; Rabbits; Rats; Rats, Inbred Strains; Serotonin; Skin; Skin Physiological Phenomena; Thiazoles; Trypan Blue | 1986 |
Pharmacologic analysis of 1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine-induced increases in cutaneous vascular permeability in the rat.
Topics: Animals; Capillary Permeability; Chromones; Dose-Response Relationship, Drug; Indomethacin; Masoprocol; Methysergide; Nifedipine; Phenoxybenzamine; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Rats; Theophylline; Thiazoles | 1987 |
Interactions between granulocytes and platelets with the guinea-pig lung in passive anaphylactic shock. Correlations with PAF-acether-induced lesion.
Topics: Anaphylaxis; Animals; Blood Platelets; Bronchial Spasm; Female; Granulocytes; Guinea Pigs; Lung; Male; Microscopy, Electron; Platelet Activating Factor; Pyrilamine; Vasoconstriction | 1987 |
Effects of WEB 2086, a novel antagonist of platelet activating factor, in active and passive anaphylaxis.
Topics: Administration, Oral; Anaphylaxis; Animals; Azepines; Blood Pressure; Guinea Pigs; Immunization; Immunization, Passive; Injections, Intravenous; Male; Mice; Ovalbumin; Platelet Activating Factor; Pyrilamine; Respiration; Triazines; Triazoles | 1987 |
Pharmacological control of the in vivo passive anaphylactic shock by the PAF-acether antagonist compound BN 52021.
Topics: Anaphylaxis; Animals; Bronchi; Diterpenes; Ginkgolides; Guinea Pigs; Lactones; Plant Extracts; Platelet Activating Factor; Propranolol; Pyrilamine; Thrombocytopenia | 1986 |
PAF-acether-induced plasma exudation in rat skin is independent of platelets and neutrophils.
Topics: Animals; Blood Platelets; Blood Proteins; Capillary Permeability; Indomethacin; Male; Methysergide; Microscopy, Electron; Neutrophils; Platelet Activating Factor; Pyrilamine; Rats; Rats, Inbred Strains; Skin | 1984 |
Non-steroidal anti-inflammatory drugs if combined with anti-histamine and anti-serotonin agents interfere with the bronchial and platelet effects of "platelet-activating factor" (PAF-acether).
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Blood Platelets; Bronchi; Drug Interactions; Histamine Antagonists; Humans; In Vitro Techniques; Methysergide; Muscle Contraction; Platelet Activating Factor; Pyrilamine; Serotonin Antagonists | 1982 |
Capsaicin sensitive nerves in the jejunum of Nippostrongylus brasiliensis-sensitized rats participate in a cardiovascular depressor reflex.
Topics: Anaphylaxis; Animals; Animals, Newborn; Blood Pressure; Capsaicin; Diterpenes; Ginkgolides; Guanethidine; Hemodynamics; Indomethacin; Jejunum; Lactones; Male; Neurons, Afferent; Nippostrongylus; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Reflex; Ruthenium Red; Strongylida Infections | 1993 |
Mast cell mediators and peritoneal adhesion formation in the rat.
Topics: Animals; Azepines; Disease Models, Animal; Histamine Antagonists; Leukotriene D4; Male; Mast Cells; Methysergide; Ondansetron; Peritoneal Diseases; Platelet Activating Factor; Propionates; Pyrilamine; Quinolines; Ranitidine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Adhesions; Triazoles | 1995 |
The effects of anti-PAF and other agents on the nasal symptoms in sensitized guinea pigs.
Topics: Airway Resistance; Animals; Azepines; Chromones; Guinea Pigs; Histamine H1 Antagonists; Immunization; Lipoxygenase Inhibitors; Male; Ovalbumin; Phthalazines; Platelet Activating Factor; Pyrilamine; Rhinitis, Allergic, Perennial; Sneezing; SRS-A; Thiazoles; Thiazolidines; Triazoles | 1993 |
The mediators involved in endotoxin-induced vascular permeability increase in the rat skin and their interactions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Dose-Response Relationship, Drug; Drug Synergism; Escherichia coli; Extravasation of Diagnostic and Therapeutic Materials; Histamine; Histamine H1 Antagonists; Indomethacin; Isoquinolines; Lipopolysaccharides; Male; Methysergide; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyridinium Compounds; Pyrilamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Skin; Specific Pathogen-Free Organisms; Tetrahydroisoquinolines | 1996 |
Histamine augments VCAM-1 expression on IL-4- and TNF-alpha-stimulated human umbilical vein endothelial cells.
Topics: Amanitins; Antibodies, Blocking; Antigens, CD; Cell Adhesion; Cells, Cultured; Cimetidine; Eosinophils; Histamine; Histamine Antagonists; Humans; Immunohistochemistry; Integrin alpha4; Interleukin-4; Piperidines; Platelet Activating Factor; Pyrilamine; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1996 |
Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF).
Topics: Administration, Oral; Animals; Azepines; Blood Pressure; Cyproheptadine; Dogs; Guinea Pigs; Histamine Antagonists; Male; Mice; Motor Activity; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine.
Topics: Animals; Blood Platelets; Calcium; Histamine; Histamine H1 Antagonists; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrilamine; Rabbits; Thromboxane B2 | 1997 |
Effect of DP-1904, a thromboxane synthetase inhibitor, on antigen- and spasmogen-induced bronchoconstriction in rodents.
Topics: Acetylcholine; Animals; Antigens; Arachidonic Acid; Bradykinin; Bronchoconstriction; Bronchoconstrictor Agents; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Indomethacin; Leukotriene D4; Male; Methacrylates; Platelet Activating Factor; Pyrilamine; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Thromboxane-A Synthase | 1999 |
Mechanisms of Helicobacter pylori-induced rat gastric mucosal microcirculatory disturbances in vivo.
Topics: Animals; Arginine; Blood Platelets; Dinoprostone; Gastric Mucosa; Helicobacter pylori; Histamine H1 Antagonists; Ketotifen; Leukocytes; Leukotriene B4; Male; Microcirculation; Microscopy, Fluorescence; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrilamine; Rats; Rats, Wistar; Serum Albumin; Thromboxane A2 | 2000 |
Changes in self-reactive IgG antibody repertoire after treatment of experimental autoimmune encephalomyelitis with anti-allergic drugs.
Topics: Animals; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Central Nervous System; Electrophoresis; Encephalomyelitis, Autoimmune, Experimental; Female; Histamine Antagonists; Histamine H1 Antagonists; Immunoblotting; Immunoglobulin G; Intermediate Filament Proteins; Malate Dehydrogenase; Mice; Mice, Inbred Strains; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteomics; Pyridinium Compounds; Pyrilamine; Receptors, G-Protein-Coupled; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |