Compounds > pyridoxine

pyridoxine and methyldopa

pyridoxine has been researched along with methyldopa in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Campanini, T; Catalano, A; De Risio, C; Forino, V1
Coquillat, G; Kurtz, D; Mack, G; Maitrot, D; Mandel, P; Micheletti, G; Rohmer, F; Warter, JM1
Curzon, G; Green, AR1
Hartmann-von Monakow, K1
Bell, MA; Cotzias, GC; Düby, SE; Fehling, C; Papavasiliou, PS; Steck, AJ1
Fahn, S1
Barrera, ER; Bennett, S; Mars, H1
Neumann, NU1
KAHLSON, G; ROSENGREN, E; THUNBERG, R1

Reviews

1 review(s) available for pyridoxine and methyldopa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for pyridoxine and methyldopa

ArticleYear
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
    Revue neurologique, 1973, Volume: 128, Issue:5

    Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Differential; Dibenzazepines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Electroencephalography; Epilepsy; Friedreich Ataxia; Humans; Hydroxyindoleacetic Acid; Ketones; Male; Methyldopa; Methysergide; Myoclonus; Neurotransmitter Agents; Nitro Compounds; Pyridoxine; Serotonin; Synaptic Transmission; Tranquilizing Agents

1973
Levodopa in Parkinsonism: potentiation of central effects with a peripheral inhibitor.
    The New England journal of medicine, 1972, Jan-06, Volume: 286, Issue:1

    Topics: Administration, Oral; Adult; Biotransformation; Brain; Carbon Monoxide Poisoning; Cerebral Palsy; Child; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Methyldopa; Neurologic Examination; Neuromuscular Diseases; Parkinson Disease; Phenylacetates; Pyridoxine; Time Factors

1972

Other Studies

12 other study(ies) available for pyridoxine and methyldopa

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Tardive dyskinesia. Synthetic-critical review and case contribution].
    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma, 1977, Volume: 48, Issue:1

    Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Disorders; Methyldopa; Middle Aged; Pyridoxine; Substance Withdrawal Syndrome; Tetrabenazine; Tranquilizing Agents; Valproic Acid

1977
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
[Specific therapy of extrapyramidal-motor syndromes].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Analgesics; Athetosis; Chorea; Datura stramonium; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Extrapyramidal Tracts; Female; Humans; Huntington Disease; Methyldopa; Movement Disorders; Myoclonus; Parasympatholytics; Parkinson Disease; Parkinson Disease, Postencephalitic; Phenothiazines; Physical Therapy Modalities; Phytotherapy; Plants, Medicinal; Plants, Toxic; Pregnancy; Pyridoxine; Reserpine; Scopolamine; Stereotaxic Techniques; Tranquilizing Agents

1969
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine

1974
Levadopa and pyridoxine.
    JAMA, 1972, Mar-27, Volume: 219, Issue:13

    Topics: Animals; Brain; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Drug Interactions; Humans; Hydrazines; Injections, Intraperitoneal; Methyldopa; Mice; Parkinson Disease; Propionates; Pyridoxine

1972
[Drug therapy in tardive dyskinesia].
    Fortschritte der Medizin, 1980, Nov-13, Volume: 98, Issue:42

    Topics: Diagnosis, Differential; Dopamine Antagonists; Dyskinesia, Drug-Induced; Humans; Lithium; Methyldopa; Parasympathomimetics; Pyridoxine; Tiapamil Hydrochloride; Tranquilizing Agents; Tryptophan

1980
OBSERVATIONS ON THE INHIBITION OF HISTAMINE FORMATION.
    The Journal of physiology, 1963, Volume: 169

    Topics: Anti-Allergic Agents; Carbon Isotopes; Carboxy-Lyases; Chromatography; Cortisone; Enzyme Inhibitors; Gastric Juice; Histamine; Histamine H1 Antagonists; Histidine; Hydrazines; Mast Cells; Methyldopa; Physiology; Prednisolone; Pyridoxal Phosphate; Pyridoxine; Rats; Research; Urine

1963