pyridoxine and methotrexate

pyridoxine has been researched along with methotrexate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gatzemeier, U; Jüngst, G; Wagner, G1
Snodgrass, SR1
Hennemann, HH; Loewe, U1
Brody, S; Kumlien, A; Paul, KG1
Soloway, MS1
BRINDLE, SD; HIRSCHBERG, E; SEMENTE, G1
Alarcón, GS; Baggott, JE; Lee, JY; Morgan, SL; Oster, RA1

Reviews

2 review(s) available for pyridoxine and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Vitamin neurotoxicity.
    Molecular neurobiology, 1992,Spring, Volume: 6, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Avitaminosis; Blood-Brain Barrier; Carrier Proteins; Coenzymes; Drug Interactions; Folic Acid; Humans; Injections, Spinal; Liver; Methotrexate; Nervous System Diseases; Oxidation-Reduction; Pseudotumor Cerebri; Pyridoxine; Self Medication; Vitamin A; Vitamins

1992

Trials

2 trial(s) available for pyridoxine and methotrexate

ArticleYear
Systemic therapy for superficial bladder cancer.
    Urology, 1984, Volume: 23, Issue:4 Suppl

    Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; FANFT; Female; Fluorouracil; Humans; Male; Methotrexate; Mice; Neoplasm Recurrence, Local; Pyridoxine; Urinary Bladder Neoplasms; Vitamin A

1984
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis.
    Arthritis and rheumatism, 2004, Volume: 50, Issue:10

    Topics: Adenosine; Aminoimidazole Carboxamide; Arthritis, Rheumatoid; Erythrocytes; Female; Folic Acid; Homocysteine; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Purines; Pyridoxine; Ribonucleotides; Treatment Outcome; Vitamin B 12

2004

Other Studies

9 other study(ies) available for pyridoxine and methotrexate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[Chemotherapy of inoperable endothoracic tumours (results of the Karrer and aco polycytostatic therapy) (author's transl)].
    Praxis und Klinik der Pneumologie, 1979, Volume: 33, Issue:1

    Topics: Adult; Aged; Bronchial Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Pyridoxine; Thoracic Neoplasms; Vinca Alkaloids; Vitamin B 12

1979
[Therapy of erythroleukemia].
    Minerva medica, 1972, Apr-25, Volume: 63, Issue:31

    Topics: Cytarabine; Folic Acid; Humans; Leukemia, Erythroblastic, Acute; Mercaptopurine; Methotrexate; Prednisone; Pyridoxine; Remission, Spontaneous; Vitamin B 12

1972
Studies on eosinophil granulocytes. II. The effect of cytostatics on the uterine response to oestrogen.
    Experientia, 1966, Dec-15, Volume: 22, Issue:12

    Topics: Animals; Castration; Catalase; Chloramphenicol; Eosinophils; Estrogens; Female; Fluorouracil; Liver; Mercaptopurine; Methotrexate; Mice; Organ Size; Peroxidases; Pyridoxine; Streptomycin; Triazoles; Uterus

1966
DEVELOPMENT AND PROPERTIES OF MOUSE LEUKEMIA L1210 RESISTANT TO MIRACIL D.
    Cancer research, 1964, Volume: 24

    Topics: Adenine; Animals; Azaguanine; Cyclophosphamide; Enzyme Inhibitors; Folic Acid; Glutamates; Guanine; Leucovorin; Leukemia L1210; Lucanthone; Mercaptopurine; Methotrexate; Mice; Pharmacology; Proadifen; Pyridoxine; Research; Thioguanine

1964