Compounds > pyridoxine

pyridoxine and acetaminophen

pyridoxine has been researched along with acetaminophen in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bonke, D; Carlsson, KH; Jurna, I; Kömen, W1
Rothman, KJ; Zierler, S1
Hayashi, Y; Hirai, D; Kosugi, A; Kumada, S; Oishi, T; Onuki, Y; Shirotori, K; Takayama, K; Tsuji, T1
Choi, SM; De, U; Kacew, S; Kim, HS; Kim, MK; Lee, BM; Lim, DS; Lim, SK; Roh, T; Yoon, S1

Reviews

1 review(s) available for pyridoxine and acetaminophen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for pyridoxine and acetaminophen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Acute effects of vitamin B6 and fixed combinations of vitamin B1, B6 and B12 on nociceptive activity evoked in the rat thalamus: dose-response relationship and combinations with morphine and paracetamol.
    Klinische Wochenschrift, 1990, Jan-19, Volume: 68, Issue:2

    Topics: Acetaminophen; Afferent Pathways; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Male; Morphine; Neurons; Nociceptors; Pyridoxine; Rats; Rats, Inbred Strains; Spinal Cord; Sural Nerve; Synaptic Transmission; Thalamic Nuclei; Vitamin B Complex

1990
Congenital heart disease in relation to maternal use of Bendectin and other drugs in early pregnancy.
    The New England journal of medicine, 1985, Aug-08, Volume: 313, Issue:6

    Topics: Acetaminophen; Adult; Anti-Bacterial Agents; Antiemetics; Aspirin; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Heart Defects, Congenital; Humans; Hyperemesis Gravidarum; Infant, Newborn; Male; Maternal-Fetal Exchange; Mental Recall; Pregnancy; Pregnancy Trimester, First; Pyridines; Pyridoxine; Surveys and Questionnaires

1985
Relationships between response surfaces for tablet characteristics of placebo and API-containing tablets manufactured by direct compression method.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Acetaminophen; Cellulose; Drug Compounding; Drug Design; Excipients; Lactose; Niacin; Placebos; Pressure; Pyridoxine; Salicylamides; Starch; Stearic Acids; Tablets

2017
Detoxifying effect of pyridoxine on acetaminophen-induced hepatotoxicity via suppressing oxidative stress injury.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 114

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cytochromes c; Glutathione; Glutathione Peroxidase; Hep G2 Cells; Humans; Lipid Peroxidation; Liver; Male; Malondialdehyde; Mice, Inbred ICR; Oxidative Stress; Pyridoxine

2018