pyridoxic acid has been researched along with probenecid in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, W; Gan, J; Gu, X; Humphreys, WG; Lai, Y; Marathe, P; Mcnaney, CA; Nelson, DM; Oliveira, RV; Reily, MD; Shen, H; Shipkova, PA; Su, C; Zhang, Y | 1 |
| Ahmad, A; Galetin, A; Jacobs, F; Kunze, A; Ogungbenro, K; Rostami-Hodjegan, A; Snoeys, J | 1 |
| Hao, J; Lai, Y; Liu, R; Zhao, X | 1 |
| Galetin, A; Rostami-Hodjegan, A; Scotcher, D; Shen, H; Snoeys, J; Tan, SPF; Willemin, ME | 1 |
| Prasad, B; Saradhi Mettu, V; Singh, DK; Thakur, A | 1 |
1 trial(s) available for pyridoxic acid and probenecid
| Article | Year |
|---|---|
Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters.
Topics: Biomarkers; Computer Simulation; Cross-Over Studies; Drug Interactions; Female; Healthy Volunteers; Homovanillic Acid; Humans; Male; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2021 |
4 other study(ies) available for pyridoxic acid and probenecid
| Article | Year |
|---|---|
Discovery and Validation of Pyridoxic Acid and Homovanillic Acid as Novel Endogenous Plasma Biomarkers of Organic Anion Transporter (OAT) 1 and OAT3 in Cynomolgus Monkeys.
Topics: Animals; Biological Transport; Biomarkers; Cell Line; HEK293 Cells; Homovanillic Acid; Humans; Macaca fascicularis; Metabolomics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2018 |
Characterization of Elimination Pathways and the Feasibility of Endogenous Metabolites as Biomarkers of Organic Anion Transporter 1/3 Inhibition in Cynomolgus Monkeys.
Topics: Animals; Biomarkers; Drug Interactions; Feasibility Studies; Homovanillic Acid; Humans; Kidney; Kynurenic Acid; Macaca fascicularis; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid | 2023 |
Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker-Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease.
Topics: Biomarkers; Drug Interactions; Humans; Kidney; Models, Biological; Probenecid; Pyridoxic Acid; Renal Insufficiency, Chronic | 2023 |
Effect of probenecid on blood levels and renal elimination of furosemide and endogenous compounds in rats: Discovery of putative organic anion transporter biomarkers.
Topics: Animals; Biomarkers; Drug Interactions; Furosemide; Kidney; Kynurenic Acid; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Probenecid; Pyridoxic Acid; Rats; Renal Elimination | 2023 |