pyridoxamine and pyruvaldehyde

pyridoxamine has been researched along with pyruvaldehyde in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's7 (46.67)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Biemel, KM; Lederer, MO; Mally, A; Nagaraj, RH; Padayatti, PS; Sarkar, P1
Chetyrkin, SV; Chuang, P; Ham, AJ; Hudson, BG; Mathieson, PW; Pedchenko, VK; Saleem, MA; Voziyan, PA1
Nagaraj, RH; Padival, S1
Ahmad, MS; Ahmed, N; Pischetsrieder, M1
Barter, PJ; Brown, BE; Davies, MJ; Nobécourt, E; Rye, KA; Yadav, S; Zeng, J1
Kim, CS; Kim, J; Kim, JS; Kim, NH; Sohn, E1
Brownstein, S; Milne, R1
Almeida, F; Crisóstomo, J; Gonçalves, L; Matafome, P; Rodrigues, T; Santos-Silva, D; Seiça, R; Sena, C1
Cardoso, S; Carvalho, C; Marinho, R; Matafome, P; Moreira, PI; Santos, MS; Seiça, RM; Sena, CM; Simões, A1
Amarnath, K; Amarnath, V; Avance, J; Stec, DF; Voziyan, P1
Aldini, G; Carini, M; Casali, G; Colzani, M; De Maddis, D; Vistoli, G1
Hendriks, JJA; Miyata, T; Schalkwijk, CG; Scheijen, JLJM; Vanmierlo, T; Wetzels, S; Wouters, K1
Bao, X; Huang, Y; Lai, K; Miao, J1
Dong, J; Guan, H; Jiang, M; Liu, Y; Lu, S; Niu, Y; Song, F; Tang, J; Tian, M; Yakupu, A1
Eussen, SJMP; Hanssen, NMJ; Houben, AJHM; Kusters, YHAM; Linkens, AMA; Miyata, T; Niessen, PM; Schalkwijk, CG; Scheijen, JLJM; Simons, N; Stehouwer, CDA; Van den Eynde, MDG1

Reviews

1 review(s) available for pyridoxamine and pyruvaldehyde

ArticleYear
Advanced glycation end products and diabetic retinopathy.
    Amino acids, 2013, Volume: 44, Issue:6

    Topics: Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Glycation End Products, Advanced; Molecular Targeted Therapy; Neovascularization, Pathologic; Pericytes; Pyridoxamine; Pyruvaldehyde; Retina; Signal Transduction

2013

Trials

1 trial(s) available for pyridoxamine and pyruvaldehyde

ArticleYear
Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial.
    Diabetes, obesity & metabolism, 2023, Volume: 25, Issue:5

    Topics: Female; Glycation End Products, Advanced; Humans; Insulin Resistance; Magnesium Oxide; Maillard Reaction; Male; Middle Aged; Obesity; Pyridoxamine; Pyruvaldehyde

2023

Other Studies

13 other study(ies) available for pyridoxamine and pyruvaldehyde

ArticleYear
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
    Archives of biochemistry and biophysics, 2002, Jun-01, Volume: 402, Issue:1

    Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Diabetes Mellitus, Experimental; Dimerization; Erythrocytes; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Chemical; Oxidative Stress; Pyridoxamine; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances

2002
Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy.
    Diabetes, 2005, Volume: 54, Issue:10

    Topics: Aldehydes; Arginine; Binding Sites; Cell Adhesion; Cell Physiological Phenomena; Collagen Type IV; Diabetic Nephropathies; Endothelial Cells; Extracellular Matrix; Extracellular Matrix Proteins; Glucose; Glyoxal; Humans; Integrin alphaVbeta3; Integrins; Kidney; Kidney Glomerulus; Pyridoxamine; Pyruvaldehyde; Umbilical Veins

2005
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
    Ophthalmic research, 2006, Volume: 38, Issue:5

    Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lens Diseases; Lens, Crystalline; Lysine; Maillard Reaction; Male; Organ Culture Techniques; Ornithine; Pyridoxamine; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

2006
Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts.
    European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3

    Topics: Aging; Antioxidants; Cysteine; Diabetes Complications; Electrophoresis, Polyacrylamide Gel; Free Radicals; Garlic; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Muramidase; Peptide Fragments; Plant Extracts; Pyridoxamine; Pyruvaldehyde; Ribose

2007
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.
    Diabetologia, 2008, Volume: 51, Issue:6

    Topics: Apolipoprotein A-I; Arginine; Cross-Linking Reagents; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Lysine; Metformin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyridoxamine; Pyruvaldehyde; Thiazoles; Tryptophan

2008
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Apoptosis; Caspase 3; Cell Line; Deoxyguanosine; DNA Damage; Epithelial Cells; Glycation End Products, Advanced; Humans; Lens, Crystalline; Ornithine; Oxidative Stress; Pyridoxamine; Pyrimidines; Pyruvaldehyde

2010
Pyridoxamine reverts methylglyoxal-induced impairment of survival pathways during heart ischemia.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Glycation End Products, Advanced; JNK Mitogen-Activated Protein Kinases; Myocardial Ischemia; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridoxamine; Pyruvaldehyde; Rats; Rats, Wistar

2013
Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status.
    Journal of bioenergetics and biomembranes, 2014, Volume: 46, Issue:5

    Topics: Animals; Brain; Energy Metabolism; Glycation End Products, Advanced; Glyoxal; Male; Mitochondria; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Pyridoxamine; Pyruvaldehyde; Random Allocation; Rats; Rats, Wistar

2014
5'-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1,2-Dicarbonyls.
    Chemical research in toxicology, 2015, Jul-20, Volume: 28, Issue:7

    Topics: Biocatalysis; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glucose; Horseradish Peroxidase; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Molecular Conformation; Muramidase; Pyridoxamine; Pyruvaldehyde; Spectrophotometry, Ultraviolet; Superoxide Dismutase

2015
Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study.
    ChemMedChem, 2016, Aug-19, Volume: 11, Issue:16

    Topics: Aldehydes; Carnosine; Dose-Response Relationship, Drug; Glyoxal; Guanidines; Humans; Hydralazine; Malondialdehyde; Molecular Structure; Pyridoxamine; Pyruvaldehyde; Sequestering Agents; Structure-Activity Relationship

2016
Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression.
    International journal of molecular sciences, 2018, Apr-27, Volume: 19, Issue:5

    Topics: Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Glycation End Products, Advanced; Glycolysis; Humans; Lactoylglutathione Lyase; Mice; Mice, Inbred C57BL; Pyridoxamine; Pyruvaldehyde; Spinal Cord; Vitamin B Complex

2018
Revealing a key inhibitory mechanism of 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline via trapping of methylglyoxal.
    Journal of food science, 2020, Volume: 85, Issue:7

    Topics: Amines; Animals; Cooking; Fish Products; Hot Temperature; Hydroxybenzoates; Mutagens; Pyridoxamine; Pyruvaldehyde; Quinoxalines; Tilapia; Vitamins

2020
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
    International wound journal, 2022, Volume: 19, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Macrophages; Mice; Pyridoxamine; Pyruvaldehyde; Wound Healing

2022