pyridoxal phosphate has been researched along with vigabatrin in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| De Biase, D; Pascarella, S; Toney, MD | 1 |
| Boesiger, P; Mueller, SG; Weber, OM; Wieser, HG | 1 |
| Bossa, F; Bruno, S; De Biase, D; Mozzarelli, A; Peneff, C; Schirmer, T; Silverman, RB; Storici, P | 1 |
| Carter, RJ; Fisher, AJ; Langston, JA; Liu, W; Peterson, PE; Toney, MD; Zhou, X | 1 |
| Kang, TC; Kim, DS; Kim, JE; Kwak, SE; Won, MH | 1 |
| Gökcan, H; Monard, G; Sungur Konuklar, FA | 1 |
1 trial(s) available for pyridoxal phosphate and vigabatrin
| Article | Year |
|---|---|
Influence of pyridoxal 5'-phosphate alone and in combination with vigabatrin on brain GABA measured by 1H-NMR-spectroscopy.
Topics: Adult; Anticonvulsants; Brain Chemistry; Creatine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Pyridoxal Phosphate; Vigabatrin | 2001 |
6 other study(ies) available for pyridoxal phosphate and vigabatrin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities.
Topics: 4-Aminobutyrate Transaminase; Amino Acid Sequence; Animals; Binding Sites; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hydrogen Bonding; Isoenzymes; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology; Structure-Activity Relationship; Substrate Specificity; Swine; Vigabatrin | 1995 |
Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin.
Topics: 4-Aminobutyrate Transaminase; Anticonvulsants; Crystallography, X-Ray; gamma-Aminobutyric Acid; Image Processing, Computer-Assisted; Iron-Sulfur Proteins; Models, Molecular; Molecular Conformation; Protein Conformation; Pyridoxal Phosphate; Vigabatrin | 2004 |
Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Binding Sites; Carboxy-Lyases; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Ligands; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Structural Homology, Protein; Substrate Specificity; Swine; Vigabatrin | 2004 |
The co-treatments of vigabatrin and P2X receptor antagonists protect ischemic neuronal cell death in the gerbil hippocampus.
Topics: Adenosine Triphosphatases; Animals; Cell Death; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Gerbillinae; Hippocampus; Immunohistochemistry; Ischemia; Male; Neurons; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Time Factors; Vigabatrin | 2006 |
Molecular dynamics simulations of apo, holo, and inactivator bound GABA-at reveal the role of active site residues in PLP dependent enzymes.
Topics: 4-Aminobutyrate Transaminase; Animals; Catalytic Domain; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyridoxal Phosphate; Pyridoxamine; Swine; Vigabatrin | 2016 |