pyridoxal phosphate has been researched along with tyrosine in 111 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 76 (68.47) | 18.7374 |
| 1990's | 12 (10.81) | 18.2507 |
| 2000's | 14 (12.61) | 29.6817 |
| 2010's | 7 (6.31) | 24.3611 |
| 2020's | 2 (1.80) | 2.80 |
| Authors | Studies |
|---|---|
| Gibbons, I; Ritchey, JM; Schachman, HK | 1 |
| Raso, V; Stollar, BD | 3 |
| Christie, EA; Farley, JR; Segel, IH; Seubert, PA | 1 |
| Awapara, J; Srinivasan, K | 1 |
| Bhagavan, HN; Coursin, DB; Koogler, JM | 1 |
| Bacharach, AD; Markland, FS; O'Grady, TC; Saunders, GC; Umemura, N; Weber, BH | 1 |
| Kumagai, H; Utagawa, T; Yamada, H | 1 |
| Kumagai, H; Yamada, H | 1 |
| Fellman, JH; Fujita, TS; Roth, ES | 1 |
| Bayomi, RA; Smith, WR | 1 |
| Fujimoto, H; Haneda, M; Nakatsuka, M; Nisimoto, Y; Nomura, S; Ohta, T; Shibata, Y; Takeuchi, F; Tamai, T; Tsubouchi, R | 1 |
| Higuchi, T; Hirotsu, K; Inoue, K; Kagamiyama, H; Kuramitsu, S; Morino, Y; Okamoto, A | 1 |
| Palm, D; Schinzel, R | 1 |
| Goldberg, JM; Goodman, HS; Kirsch, JF; Swanson, RV | 1 |
| Balasubramanian, KA; Baskaran, S | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Hamfelt, A | 4 |
| Kakizono, T; Nihira, T; Taguchi, H | 1 |
| Reynolds, RD; Thompson, SD | 1 |
| Murali, DK; Radhakrishnan, AN | 1 |
| Flanagan, TH; John, RA; Rose, FA | 1 |
| Steinberg, IZ | 1 |
| Zenker, N | 1 |
| Tryfiates, GP | 1 |
| DeVivo, DC; Peterkofsky, B | 1 |
| Litwack, G; Rosenberg, JS | 1 |
| Gallagher, BB | 1 |
| Kumagai, H; Nakazawa, H; Yamada, H | 1 |
| Diven, WF; Grever, MR; Meneely, RL; Neary, JT | 1 |
| Aloj, S; Bruni, CB; Edelhoch, H; Rechler, MM | 1 |
| Fukui, S; Masugi, F; Natori, Y; Shimizu, S | 2 |
| Hornykiewicz, O; Lloyd, KG | 1 |
| Reinken, L | 1 |
| Fukui, S; Kumagai, H; Masugi, F; Yamada, H | 1 |
| Bocharov, AL; Demidkina, TV; Karpeiskii, MY; Polyanovskii, OL | 1 |
| Fahien, LA; Smith, SE | 1 |
| Kumagai, H; Matsui, H; Ogata, K; Ohkishi, H; Yamada, H | 2 |
| Duhault, J; Gonnard, P; Nguyen-Philippon, C | 1 |
| Fukami, H; Kumagai, H; Matsui, H; Ogata, K; Ohgishi, H; Ueno, T; Yamada, H | 1 |
| Coursin, DB; Maruyama, H | 1 |
| Enei, H; Kashima, N; Kumagai, H; Okumura, S; Torii, H; Yamada, H | 1 |
| Anderson, JA; Chang, HW; Grandjean, CJ | 1 |
| Goldstone, AD; Needleman, SB | 1 |
| Cornish, HH | 1 |
| De Ropp, RS; Furst, A | 1 |
| Gabay, S; Huang, KH | 1 |
| Burkard, WP; Gey, KF | 1 |
| Kashima, N; Kumagai, H; Yamada, H | 1 |
| Christen, P; Riordan, JF | 1 |
| Hechtman, P; Schimmel, SD; Soffer, RL | 1 |
| Soffer, RL | 1 |
| DeMoss, RD; O'Neil, SR | 1 |
| DeGroot, LJ; Jaksina, S; Karmarkar, M | 1 |
| Gabay, S; George, H | 1 |
| Bernard, P; Fenasse, R; Laurent, B; Lissitzky, S | 1 |
| Failla, DL; Hullar, TL | 1 |
| Fischer, AG; Oliner, L; Schulz, AR | 1 |
| Brot, N; Smit, Z; Weissbach, H | 1 |
| Constantsas, NS; Knox, WE | 1 |
| Ikawa, M | 1 |
| Oliner, L; Schulz, AR | 1 |
| Botteri, A; Hamfelt, A; Söderhjelm, L | 1 |
| Kumar, A; Sanwal, GG | 1 |
| Chen, HY; Demidkina, TV; Phillips, RS | 1 |
| Bickel-Sandkötter, S; Wessels, T | 1 |
| Callender, R; Chen, YQ; Deng, H; Goldberg, JM; Kirsch, JF; Zheng, J | 1 |
| Xiao, GS; Zhou, JM | 1 |
| Bertoldi, M; Borri Voltattorni, C; Dominici, P; Moore, PS | 1 |
| Brünger, AT; Shah, SA; Shen, BW | 1 |
| Bai, SC; Morris, JG; Rogers, QR; Sampson, DA; Wong, DL | 1 |
| Sun, S; Toney, MD | 1 |
| Prakash, V; Rao, JV; Rao, NA; Savithri, HS | 1 |
| Beaulieu, G; Duguay, C; Livingstone, MM; Massé, PG | 1 |
| di Salvo, ML; Ko, TP; Musayev, FN; Raboni, S; Safo, MK; Schirch, V | 1 |
| Barbolina, MV; Demidkina, TV; Faleev, NG; Gollnick, PD; Phillips, RS; Sundararaju, B | 1 |
| Badr, A; Kimura, H; Meguro, T; Zhang, JH | 1 |
| BELK, WF; FLAA, RC; JACOBS, FA | 1 |
| BRIGGS, MH | 1 |
| SEKERIS, CE | 1 |
| DIAMONDSTONE, TI; LITWACK, G | 1 |
| GORDON, M; GREENGARD, O | 1 |
| HARRINGTON, H; SAKAMI, W | 1 |
| MICHALEK-MORICCA, H | 1 |
| CHEVILLARD, L; van THOAI, N | 1 |
| CHEVILLARD, L | 1 |
| Kao, CL; Karthikeyan, S; Liu, HW; Robinson, H; Tao, Z; Zhang, H; Zhao, Z; Zhou, Q | 1 |
| Hewlins, MJ; John, RA; Markova, M; Peneff, C; Schirmer, T | 1 |
| Bertoldi, M; Borri Voltattorni, C; Cellini, B; Montioli, R | 1 |
| Marcobal, A; Martín-Alvarez, PJ; Moreno-Arribas, MV; Muñoz, R | 1 |
| Sloane-Stanley, GH | 1 |
| Antson, AA; Demidkina, TV; Kulikova, VV; Matković-Calogović, D; Milić, D; Sinitzina, NI | 1 |
| Rahbar, S | 1 |
| Crooke, A; Guzmán-Aránguez, A; Pintor, J; Yayon, A | 1 |
| Bertoldi, M; Cellini, B; Montioli, R; Paiardini, A; Voltattorni, CB | 1 |
| Appaji Rao, N; Bhavani, BS; Bisht, S; Kaul, P; Murthy, MR; Prakash, V; Rajaram, V; Savithri, HS | 1 |
| Blau, N; Dill, P; Jakobs, C; Schneider, J; Tekin, M; Thöny, B; Trachsel, D; Weber, P | 1 |
| Dyukova, E; Lupachyk, S; Obrosova, IG; Shevalye, H; Stavniichuk, R; Watcho, P | 1 |
| Li, B; Sun, H; Wang, C; Zhu, R | 1 |
| Curien, G; Giustini, C; Graindorge, M; Kraut, A; Matringe, M; Moyet, L | 1 |
| Hemmi, H; Ito, T; Koga, K; Matsuoka, M; Yoshimura, T | 1 |
| Angelaccio, S; Angelucci, F; Contestabile, R; Ilari, A; Morea, V; Saccoccia, F | 1 |
| Allegrini, A; Astegno, A; Dominici, P; Giorgetti, A; Piccoli, S | 1 |
| Akiyama, T; Baba, S; Dowa, Y; Fukuyama, T; Hamano, SI; Hasegawa, K; Hyodo, Y; Imai, K; Ishihara, N; Kobayashi, K; Koike, T; Kubota, M; Oboshi, T; Okanishi, T; Shibasaki, J; Shimbo, H; Shiraku, H; Takano, K; Takeshita, S; Yamamoto, T | 1 |
| Bazhulina, NP; Demidkina, TV; Koval, VS; Kulikova, VV; Lyfenko, AD; Morozova, EA; Revtovich, SV | 1 |
2 review(s) available for pyridoxal phosphate and tyrosine
| Article | Year |
|---|---|
Long-range nonradiative transfer of electronic excitation energy in proteins and polypeptides.
Topics: Adrenocorticotropic Hormone; Catalase; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Copper; Dipeptides; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Hemoglobins; Indoles; Insulin; L-Lactate Dehydrogenase; Mathematics; Monoiodotyrosine; Myoglobin; NAD; Parathyroid Hormone; Peptides; Phenols; Phenylalanine; Phosphoric Acids; Picolines; Plant Proteins; Proteins; Pyridoxal Phosphate; Thyroxine; Transferrin; Tryptophan; Tyrosine | 1971 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
109 other study(ies) available for pyridoxal phosphate and tyrosine
| Article | Year |
|---|---|
Reactivation of enzymes by light-stimulated cleavage of reduced pyridoxal 5'-phosphate-enzyme complexes.
Topics: Aspartate Carbamoyltransferase; Enzyme Activation; Histidine; Hydrogen-Ion Concentration; Kinetics; L-Serine Dehydratase; Lyases; Lysine; Magnetic Resonance Spectroscopy; Molecular Weight; Photolysis; Protein Binding; Pyridoxal Phosphate; Pyridoxamine; Tryptophanase; Tyrosine; Ultraviolet Rays | 1977 |
The antibody-enzyme analogy. Characterization of antibodies to phosphopyridoxyltyrosine derivatives.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Binding Sites, Antibody; Carrier Proteins; Chemical Precipitation; gamma-Globulins; Haptens; Protein Binding; Pyridoxal Phosphate; Rabbits; Schiff Bases; Structure-Activity Relationship; Tyrosine | 1975 |
Adenosine triphosphate sulfurylase from Penicillium chrysogenum. Evidence for essential arginine, histidine, and tyrosine residues.
Topics: Arginine; Binding Sites; Dithionitrobenzoic Acid; Histidine; Kinetics; Nucleotidyltransferases; Penicillium; Penicillium chrysogenum; Pyridoxal; Pyridoxal Phosphate; Sulfate Adenylyltransferase; Tyrosine | 1979 |
The antibody-enzyme analogy. Comparison of enzymes and antibodies specific for phosphopyridoxyltyrosine.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Binding Sites, Antibody; Enterococcus faecalis; Kinetics; Liver; Pyridoxal Phosphate; Rats; Schiff Bases; Tyrosine; Tyrosine Decarboxylase; Tyrosine Transaminase | 1975 |
Substrate specificity and other properties of DOPA decarboxylase from guinea pig kidneys.
Topics: 5-Hydroxytryptophan; Animals; Dopa Decarboxylase; Guinea Pigs; Kidney; Levodopa; Pyridoxal Phosphate; Substrate Specificity; Tyrosine | 1978 |
Enzymatic microassay of pyridoxal-5'-phosphate using L-tyrosine apodecarboxylase and L-(1-14C) tyrosine.
Topics: Apoenzymes; Carbon Dioxide; Microchemistry; Pyridoxal Phosphate; Tyrosine; Tyrosine Decarboxylase | 1976 |
Chemical modification of yeast 3-phosphoglycerate kinase.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Circular Dichroism; Kinetics; Lysine; Maleates; Molecular Weight; Nitro Compounds; Optical Rotatory Dispersion; Peptide Fragments; Phosphoglycerate Kinase; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Trypsin; Tyrosine; Urea | 1975 |
Studies on tyrosine phenol lyase. Modification of essential histidyl residues by diethylpyrocarbonate.
Topics: Alanine; Binding Sites; Borohydrides; Escherichia coli; Esters; Formates; Histidine; Hydroxylamines; Lyases; Phenols; Protein Binding; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfhydryl Compounds; Tyrosine | 1975 |
Synthesis of L-tyrosine-related amino acids by beta-tyrosinase.
Topics: Amino Acids; Ammonia; Catalysis; Catechols; Cell-Free System; Chemical Phenomena; Chemistry; Crystallization; Dihydroxyphenylalanine; Enzyme Induction; Erwinia; Escherichia; Lyases; Molecular Weight; Phenols; Pyridoxal Phosphate; Pyruvates; Sepharose; Serine; Stereoisomerism; Tyrosine; Tyrosine Phenol-Lyase | 1975 |
Decarboxylation to tyramine is not a major route of tyrosine metabolism in mammals.
Topics: Anaerobiosis; Animals; Dihydroxyphenylalanine; In Vitro Techniques; Kidney; Liver; Mice; Organ Specificity; Pyridoxal Phosphate; Rats; Species Specificity; Tyramine; Tyrosine | 1976 |
Pyridoxal-5-phosphate levels in rat brain assayed by a modified method using enzymic decarboxylation of L-[14C]tyrosine.
Topics: Aging; Animals; Brain; Brain Chemistry; Kinetics; Methods; Microchemistry; Pyridoxal Phosphate; Rats; Tyrosine; Tyrosine Decarboxylase; Vitamin B 6 Deficiency | 1976 |
On kynureninase activity.
Topics: Animals; Apoenzymes; Benzothiazoles; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrolases; Kynurenine; Liver; Magnesium; Male; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Xanthurenates | 1991 |
Tyr225 in aspartate aminotransferase: contribution of the hydrogen bond between Tyr225 and coenzyme to the catalytic reaction.
Topics: Amino Acid Sequence; Aspartate Aminotransferases; Base Sequence; Binding Sites; Escherichia coli; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Tyrosine; X-Ray Diffraction | 1991 |
Escherichia coli maltodextrin phosphorylase: contribution of active site residues glutamate-637 and tyrosine-538 to the phosphorolytic cleavage of alpha-glucans.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Escherichia coli; Glucans; Glucosyltransferases; Glutamates; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Tyrosine | 1990 |
The tyrosine-225 to phenylalanine mutation of Escherichia coli aspartate aminotransferase results in an alkaline transition in the spectrophotometric and kinetic pKa values and reduced values of both kcat and Km.
Topics: Aspartate Aminotransferases; Base Sequence; Circular Dichroism; Cloning, Molecular; Escherichia coli; Hydrogen Bonding; Kinetics; Mathematics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phenylalanine; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Tyrosine | 1991 |
Purification and active site modification studies on glyoxalase I from monkey intestinal mucosa.
Topics: Amino Acids, Dicarboxylic; Animals; Anions; Apoproteins; Binding Sites; Cations; Intestinal Mucosa; Lactoylglutathione Lyase; Lyases; Lysine; Macaca radiata; Molecular Weight; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfhydryl Compounds; Tryptophan; Tyrosine | 1987 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
A simplified method for determination of pyridoxal phosphate in biological samples.
Topics: Carbon Radioisotopes; Chromatography, High Pressure Liquid; Humans; Pyridoxal Phosphate; Radioisotope Dilution Technique; Tritium; Tyrosine; Tyrosine Decarboxylase | 1986 |
Catalytic function of a tyrosyl residue in tryptophanase.
Topics: Binding Sites; Catalysis; Escherichia coli; Kinetics; Lyases; Pyridoxal Phosphate; Spectrum Analysis; Structure-Activity Relationship; Tetranitromethane; Tryptophanase; Tyrosine | 1986 |
Irreversible inactivation of rat liver tyrosine aminotransferase.
Topics: Animals; Apoproteins; Binding Sites; Centrifugation, Density Gradient; Cross Reactions; Cysteine; Dihydroxyphenylalanine; Drug Stability; Electrophoresis, Disc; Half-Life; Hot Temperature; Hydroxylamines; Ketoglutaric Acids; Kinetics; Liver; Protein Binding; Pyridoxal Phosphate; Rats; Semicarbazides; Structure-Activity Relationship; Time Factors; Tyrosine; Tyrosine Transaminase; Ultrafiltration | 1974 |
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1970 |
A rat-tissue aminotransferase acting on L-tyrosine O-sulphate.
Topics: Animals; Electron Transport Complex IV; Hydrocortisone; In Vitro Techniques; Ketoglutaric Acids; Kidney; L-Lactate Dehydrogenase; Liver; Pancreas; Pyridoxal Phosphate; Rats; Subcellular Fractions; Sulfates; Transaminases; Tyrosine | 1966 |
The interaction of pyridoxal phosphate with tyrosine analogs.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Enzymes; Epinephrine; In Vitro Techniques; Liver; Male; Methyldopa; Methyltyrosines; Normetanephrine; Octopamine; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase; Ultraviolet Rays | 1966 |
On the synthesis of tyrosine transaminase in vitro.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Hydrocortisone; Liver; Male; Microsomes; Phenylalanine; Puromycin; Pyridoxal Phosphate; Rats; Ribonucleases; Tritium; Tyrosine; Tyrosine Transaminase | 1969 |
The effect of alpha-ketoglutarate and other alpha-keto acids on the recovery of tyrosine aminotransferase activity from chick embryo liver.
Topics: Amines; Animals; Chick Embryo; Chromatography, Gel; Enzyme Activation; Freezing; Glutamates; Hot Temperature; Keto Acids; Ketoglutaric Acids; Liver; Methods; Phosphates; Protein Denaturation; Pyridines; Pyridoxal Phosphate; Tyrosine; Tyrosine Transaminase | 1970 |
Liver cytosol tyrosine aminotransferase. Product inhibition and interaction with substrates.
Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Cytoplasm; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Liver; Male; Phenylpyruvic Acids; Phosphoric Acids; Picolines; Pyridoxal Phosphate; Rats; Tyrosine; Tyrosine Transaminase | 1970 |
The influence of tyrosine, phenylpyruvate and vitamin B 6 upon seizure thresholds.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Ethers; Fluorine; Male; Myoclonus; Phenylalanine; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Time Factors; Tyrosine | 1971 |
Constitutive aromatic L-amino acid decarboxylase from Micrococcus percitreus.
Topics: Carboxy-Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Drug Stability; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Micrococcus; Molecular Weight; Phenylalanine; Protamines; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine; Ultracentrifugation | 1974 |
The interactions between biogenic amines and pyridoxal, pyridoxal phosphate, and pyridoxal kinase.
Topics: 5-Hydroxytryptophan; Adenosine Triphosphate; Amines; Animals; Biogenic Amines; Brain; Cattle; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dopamine; Norepinephrine; Phosphotransferases; Picolines; Pyridoxal Phosphate; Pyridoxine; Serotonin; Spectrophotometry; Tryptophan; Tyrosine; Zinc | 1972 |
Physical studies comparing a genetically fused enzyme of the histidine operon with its component enzymes.
Topics: Alcohol Oxidoreductases; Amino Alcohols; Chemical Phenomena; Chemistry; Circular Dichroism; Genetics, Microbial; Histidine; Hydrogen-Ion Concentration; Imidazoles; Macromolecular Substances; Multienzyme Complexes; Operon; Peptides; Protein Conformation; Pyridoxal Phosphate; Salmonella typhimurium; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Transaminases; Tryptophan; Tyrosine | 1973 |
Comparison of coenzymatic activities of 2-nor-2-hydroxymethyl pyridoxal 5'-phosphate for mitochondrial and cytoplasmic aspartate aminotransferases.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Binding Sites; Carboxy-Lyases; Cytosol; Escherichia; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; L-Serine Dehydratase; Lyases; Mitochondria, Muscle; Myocardium; Phenols; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Structure-Activity Relationship; Swine; Tryptophanase; Tyrosine | 1973 |
Coenzymatic activities of 2-nor-2-hydroxymethyl pyridoxal 5'-phosphate for various vitamin B6 enzymes.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Aspartic Acid; Binding, Competitive; Buffers; Carboxy-Lyases; Chemical Phenomena; Chemistry; Coenzymes; Cytoplasm; Escherichia; Escherichia coli; Lyases; Mitochondria, Muscle; Myocardium; Phenols; Phosphates; Pseudomonas; Pyridoxal Phosphate; Pyridoxine; Spectrum Analysis; Swine; Tryptophanase; Tyrosine | 1973 |
Occurrence and distribution of aromatic L-amino acid (L-DOPA) decarboxylase in the human brain.
Topics: 5-Hydroxytryptophan; Aged; Aging; Animals; Basal Ganglia; Brain; Carbon Isotopes; Cats; Cattle; Caudate Nucleus; Cerebral Cortex; Chromatography, Paper; Diencephalon; Dopa Decarboxylase; Enzyme Activation; Female; Haplorhini; Humans; Hypothalamus; Male; Mesencephalon; Middle Aged; Pineal Gland; Pyridoxal Phosphate; Rats; Species Specificity; Stereoisomerism; Tyrosine | 1972 |
[Micromethod for determining serum pyridoxal-5-phosphate by decarboxylation of L-tyrosine-1- 14 C].
Topics: Apoproteins; Carbon Dioxide; Carbon Isotopes; Child; Decarboxylation; Humans; Kinetics; Methods; Microchemistry; Pyridoxal Phosphate; Tyramine; Tyrosine; Tyrosine Decarboxylase | 1972 |
Antibodies specific for conformationally distinct coenzyme-substrate transition state analogs. A fluorescence, nuclear magnetic resonance, circular dichroism, and antibody study of N-(5-phosphopyridoxyl)-3'-amino-L-tyrosine.
Topics: Amino Acid Sequence; Antibody Specificity; Binding Sites; Circular Dichroism; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis; Structure-Activity Relationship; Tyrosine | 1973 |
Interaction of tyrosine phenol-lyase with pyridoxal phosphate N-oxide and 2'-hydroxy pyridoxal phosphate.
Topics: Alanine; Apoproteins; Binding Sites; Cyclic N-Oxides; Escherichia; Lyases; Phenols; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tyrosine | 1973 |
Physicochemical and catalytic properties of aspartate aminotransferase selectively modified at the tyrosine and cysteine residues.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Binding Sites; Carbon Radioisotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Electrophoresis, Paper; Enzyme Activation; Ethylmaleimide; Ketoglutarate Dehydrogenase Complex; Methane; Myocardium; Nitro Compounds; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tyrosine | 1974 |
The enzyme-enzyme complex of transaminase and glutamate dehydrogenase.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Cattle; Chromatography, Gel; Cytoplasm; Glutamate Dehydrogenase; Glutamates; Ketoglutaric Acids; Kinetics; Macromolecular Substances; Mitochondria, Liver; Multienzyme Complexes; Myocardium; Organophosphorus Compounds; Phenylalanine; Phenylhydrazines; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxamine; Swine; Tyrosine | 1974 |
Tyrosine phenol lyase. I. Purification, crystallization, and properties.
Topics: Alanine; Amino Acids; Ammonia; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Cysteine; Electrophoresis; Escherichia coli; Feedback; Kinetics; Lyases; Methods; Molecular Weight; Phenols; Protamines; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Tyrosine; Ultracentrifugation | 1970 |
Tyrosine phenol lyase. II. Cofactor requrements.
Topics: Alanine; Amino Acids; Binding Sites; Boron Compounds; Chemical Phenomena; Chemistry; Chromatography, Paper; Dialysis; Electrophoresis; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Lysine; Phenols; Potassium; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Sodium; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1970 |
[Differential action of 2,3,4-trihydroxybenzylhydrazine on amino acid decarboxylases].
Topics: 5-Hydroxytryptophan; Animals; Aspartate Aminotransferases; Brain; Carboxy-Lyases; Dopa Decarboxylase; Escherichia coli; Glutamates; Hydrazines; Kidney; Pyridoxal Phosphate; Rabbits; Tryptophan; Tyrosine | 1967 |
Synthesis of 3,4-dihydroxyphenyl-L-alanine from L-tyrosine and pyrocatechol by crystalline beta-tyrosinase.
Topics: Autoanalysis; Catechol Oxidase; Catechols; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Escherichia; Hydrogen-Ion Concentration; Pyridoxal Phosphate; Time Factors; Tyrosine | 1969 |
Enzymic assay of pyridoxal phosphate using tyrosine apodecarboxylase and tyrosine-1-14C.
Topics: Animals; Brain Chemistry; Carbon Isotopes; Enterococcus faecalis; Liver; Male; Methods; Pyridoxal Phosphate; Rats; Tyrosine; Tyrosine Decarboxylase | 1968 |
Synthesis of L-tyrosine from pyruvate, ammonia and phenol by crystalline tyrosine phenol lyase.
Topics: Ammonia; Catechols; Dihydroxyphenylalanine; Enzyme Activation; Escherichia; Hydrogen Sulfide; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenols; Pyridoxal Phosphate; Pyruvates; Resorcinols; Spectrophotometry; Stereoisomerism; Sulfhydryl Compounds; Tyrosine | 1972 |
Nature of the binding site of pyridoxal 5'-phosphate to bovine serum albumin.
Topics: Alkanes; Amino Acid Sequence; Binding Sites; Carboxypeptidases; Chromatography, Ion Exchange; Fluorometry; Hydrogen-Ion Concentration; Lysine; Protein Binding; Pyridoxal Phosphate; Pyrrolidinones; Serum Albumin, Bovine; Spectrophotometry; Thiocyanates; Trypsin; Tyrosine; Urea | 1971 |
Effect of abnormal amino acid concentrations on blood-brain barrier.
Topics: Absorption; Amino Acids; Animals; Blood-Brain Barrier; Brain; Carbon Isotopes; Injections, Intraperitoneal; Lysine; Mice; Permeability; Pyridoxal Phosphate; Time Factors; Tissue Extracts; Tyrosine | 1971 |
The role of vitamin B6 in the toxicity of hydrazines.
Topics: Amino Acids; Animals; Brain Chemistry; Calcium; Hydrazines; Injections; Injections, Intraperitoneal; Potassium; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Sodium; Tryptophan; Tyrosine | 1969 |
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine | 1966 |
Studies of brain aminotransferase and psychotropic agents. I. Interaction of B-B'-iminodipropionitrile and rat brain aromatic aminotransferases.
Topics: 5-Hydroxytryptophan; Aminopropionitrile; Animals; Brain; Brain Chemistry; Chromatography; Chromatography, Gel; Female; Kinetics; Nitriles; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyrosine | 1969 |
Chlorpromazine-induced accumulation of pyridoxal-5'-phosphate and activation of the decarboxylase of aromatic amino acids in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Catecholamines; Chlorpromazine; Cycloheximide; Dactinomycin; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; In Vitro Techniques; Pyridoxal Phosphate; Rats; Serotonin; Time Factors; Tyrosine | 1969 |
Racemization of D- or L-alanine by crystalline tyrosine phenol-lyase from Escherichia intermedia.
Topics: Alanine; Chemical Phenomena; Chemistry; Escherichia; Hydrogen-Ion Concentration; Kinetics; Lyases; Pyridoxal Phosphate; Spectrophotometry; Tyrosine | 1970 |
Syncatalytic modification of a functional tyrosyl residue in aspartate aminotransferase.
Topics: Animals; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Circular Dichroism; Enzyme Activation; Glutamates; Hydrogen-Ion Concentration; Iodine; Ketoglutaric Acids; Methane; Myocardium; Phosphoric Acids; Picolines; Pyridoxal Phosphate; Spectrophotometry; Sulfhydryl Compounds; Swine; Tyrosine; Ultracentrifugation | 1970 |
A soluble 3,5-dinitrotyrosine aminotransferase from rabbit liver which catalyzes the transamination of thyroid hormone.
Topics: Adsorption; Amination; Animals; Calcium Phosphates; Carbon Isotopes; Catalysis; Centrifugation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Densitometry; Dinitrophenols; Electrophoresis, Disc; Iodides; Iodine Isotopes; Ketoglutaric Acids; Liver; Mercaptoethanol; Methods; Monoiodotyrosine; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rabbits; Sodium; Solubility; Spectrophotometry; Sulfates; Thyroxine; Transaminases; Triiodothyronine; Tyrosine; Ultraviolet Rays | 1971 |
Incorporation of radioactivity from monoiodotyrosine by soluble systems.
Topics: Adenosine Triphosphate; Animals; Chromatography, Paper; Cytoplasm; Diiodotyrosine; Guanine Nucleotides; Hot Temperature; Iodine; Iodine Isotopes; Ketoglutaric Acids; Liver; Magnesium; Mitochondria; Mitochondria, Liver; Peptide Hydrolases; Protein Hydrolysates; Puromycin; Pyridoxal Phosphate; Pyruvates; Rabbits; Ribonucleases; Ribosomes; Sheep; Thyroid Gland; Triiodothyronine; Tritium; Tyrosine | 1968 |
Tryptophan transaminase from Clostridium sporogenes.
Topics: Buffers; Cell-Free System; Centrifugation, Density Gradient; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Ion Exchange; Clostridium; Electrophoresis; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Models, Biological; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Transaminases; Tryptophan; Tyrosine | 1968 |
Role of pyridoxal phosphate in thyroid hormone biosynthesis.
Topics: Animals; Cattle; Copper; Hydrogen Peroxide; In Vitro Techniques; Iodides; Iodine; Iron; Manganese; Microsomes; Mitochondria; Monoiodotyrosine; Peroxidases; Pyridoxal Phosphate; Pyrogallol; Spectrophotometry; Stimulation, Chemical; Thyroid Gland; Thyroid Hormones; Tyrosine; Zinc | 1968 |
Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase.
Topics: Animals; Arsenic; Aspartic Acid; Borates; Brain; Buffers; Chemical Precipitation; Chloromercuribenzoates; Chromatography; Hydrogen-Ion Concentration; Ion Exchange; Keto Acids; Ketoglutaric Acids; Kinetics; Mercaptoethanol; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Succinates; Swine; Transaminases; Tyrosine; Vibration | 1968 |
[Experimental studies in a case of tyrosinosis. New pathogenic hypothesis].
Topics: Adult; Amino Acids; Animals; Blood Glucose; Carbon Dioxide; Chromatography; Depression, Chemical; Dietary Carbohydrates; Electrophoresis; Enzyme Induction; Female; Glycosuria; Humans; Hydrocortisone; Kidney Diseases; Kidney Tubules; Liver; Male; Metabolic Diseases; Phenols; Pregnancy; Pyridoxal Phosphate; Pyridoxine; Pyruvate Oxidase; Rats; Stimulation, Chemical; Time Factors; Transaminases; Tyrosine; Water | 1969 |
Pyridoxal phosphate. II. Benzene analogs. 2-Formylphenoxyacetic acids as potential antimetabolites of pyridoxal phosphate.
Topics: Acetates; Binding Sites; Carboxy-Lyases; Chemical Phenomena; Chemistry; Pyridoxal Phosphate; Spectrum Analysis; Streptococcus; Tyrosine | 1969 |
Thyroidal biosynthesis of iodothyronines. I. General characteristics and distribution of the bovine enzyme system.
Topics: Aldehydes; Animals; Cattle; Diiodotyrosine; In Vitro Techniques; Manganese; Microsomes; Pyridoxal Phosphate; Thyroid Gland; Thyronines; Thyroxine; Tyrosine | 1965 |
Conversion of L-tyrosine to phenol by Clostridium tetanomorphum.
Topics: Chemistry Techniques, Analytical; Clostridium; In Vitro Techniques; Phenols; Pyridoxal Phosphate; Pyruvates; Tyrosine | 1965 |
The activation of chick liver tyrosine transaminase in vitro.
Topics: Animals; Glutamates; Hydrocortisone; In Vitro Techniques; Injections, Intraperitoneal; Ketoglutaric Acids; Liver; Poultry; Pyridoxal Phosphate; Transaminases; Tryptophan; Tyrosine | 1967 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cattle; Diiodotyrosine; Histidine; In Vitro Techniques; Phenylalanine; Pyridoxal Phosphate; Thyroid Gland; Thyroxine; Tryptophan; Tyrosine | 1967 |
Pyridoxal kinase activity in blood cells.
Topics: Adenosine Triphosphate; Adult; Aged; Carbon Isotopes; Child; Child, Preschool; Erythrocytes; Humans; Hydrogen-Ion Concentration; Infant; Leukocytes; Middle Aged; Phosphotransferases; Pyridoxal Phosphate; Thyroid Diseases; Tyrosine | 1967 |
Enzymatic determination of pyridoxal phosphate in plasma by decarboxylation of L-tyrosine-14 C (U) and a comparison with the tryptophan load test.
Topics: Adult; Aged; Carbon Isotopes; Child; Chromatography, Paper; Clinical Enzyme Tests; Heparin; Humans; Methods; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Tyramine; Tyrosine; Tyrosine Decarboxylase; Vitamin B Complex; Xanthurenates | 1967 |
Pyridoxal phosphate, tryptophan, and tyrosine in blood and cerebrospinal fluid in elderly patients.
Topics: Adult; Age Factors; Aged; Humans; Hydrocephalus; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1984 |
Starch phosphorylase from tapioca leaves: absence of pyridoxal phosphate.
Topics: Chromatography, DEAE-Cellulose; Chromatography, Gel; Molecular Weight; Phosphorylases; Plants; Pyridoxal Phosphate; Sulfhydryl Compounds; Tyrosine | 1982 |
Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding.
Topics: Base Sequence; Catalysis; Circular Dichroism; Citrobacter freundii; Cysteine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 1995 |
Evidences for physically different catalytic and regulatory nucleotide binding sites on the chloroplast H(+)-ATPase.
Topics: Adenosine Diphosphate; Binding Sites; Catalysis; Chloroplasts; Hydrolysis; Light; Lysine; Molecular Weight; Nucleotides; Proton-Translocating ATPases; Pyridoxal Phosphate; Tyrosine | 1994 |
Structure of the complex between pyridoxal 5'-phosphate and the tyrosine 225 to phenylalanine mutant of Escherichia coli aspartate aminotransferase determined by isotope-edited classical Raman difference spectroscopy.
Topics: Aspartate Aminotransferases; Chemical Phenomena; Chemistry, Physical; Escherichia coli; Hydrogen Bonding; Molecular Structure; Mutation; Phenylalanine; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 1993 |
Conformational changes at the active site of bovine pancreatic RNase A at low concentrations of guanidine hydrochloride probed by pyridoxal 5'-phosphate.
Topics: Animals; Binding Sites; Cattle; Fluorescence Polarization; Guanidine; Guanidines; Kinetics; Molecular Probes; Protein Conformation; Protein Denaturation; Pyridoxal Phosphate; Ribonuclease, Pancreatic; Spectrometry, Fluorescence; Tyrosine | 1996 |
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase.
Topics: Amino Acids; Dopa Decarboxylase; Esters; Hydrogen-Ion Concentration; Methylation; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Tyrosine | 1997 |
Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition.
Topics: Aminobutyrates; Arginine; Binding Sites; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gyrate Atrophy; Humans; Models, Molecular; Molecular Sequence Data; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Transaminases; Tyrosine | 1997 |
Vitamin B-6 deficiency and level of dietary protein affect hepatic tyrosine aminotransferase activity in cats.
Topics: Animals; Cats; Circadian Rhythm; Cystathionine; Dietary Proteins; Food Deprivation; Liver; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1998 |
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine | 1999 |
The role of Glu74 and Tyr82 in the reaction catalyzed by sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Alanine; Amino Acid Substitution; Animals; Apoenzymes; Binding Sites; Calorimetry, Differential Scanning; Catalysis; Cytosol; Formaldehyde; Glutamic Acid; Glycine Hydroxymethyltransferase; Humans; Kinetics; Liver; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Rabbits; Recombinant Fusion Proteins; Serine; Sheep; Structure-Activity Relationship; Tetrahydrofolates; Tyrosine | 2000 |
Testing the tyrosine/catecholamine hypothesis of oral contraceptive-induced psychological side-effects: a controlled study on triphasil.
Topics: Adult; Amino Acids; Biomarkers; Case-Control Studies; Catecholamines; Contraceptives, Oral; Ethinyl Estradiol-Norgestrel Combination; Female; Humans; Hydrocortisone; Intestinal Absorption; Mental Disorders; Nutritional Status; Psychological Tests; Pyridoxal Phosphate; Tyrosine | 2001 |
Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase.
Topics: Arginine; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Escherichia coli; Flavin Mononucleotide; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Structure, Secondary; Pyridoxal Phosphate; Pyridoxamine; Pyridoxaminephosphate Oxidase; Stereoisomerism; Substrate Specificity; Tyrosine; Water | 2002 |
Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine.
Topics: Amino Acid Sequence; Binding Sites; Citrobacter freundii; Escherichia coli; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Sequence Alignment; Structure-Activity Relationship; Threonine; Tyrosine; Tyrosine Phenol-Lyase | 2002 |
Suramin-induced reversal of chronic cerebral vasospasm in experimental subarachnoid hemorrhage.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Chronic Disease; Dogs; Female; Male; Oxyhemoglobins; Phosphorylation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Pyridoxal Phosphate; Receptors, Purinergic P2; Subarachnoid Hemorrhage; Suramin; Tyrosine; Vasospasm, Intracranial | 2002 |
Pyridoxal phosphate requirement for intestinal absorption of L-tyrosine.
Topics: Coenzymes; Intestinal Absorption; Intestines; Pyridoxal Phosphate; Tyrosine | 1960 |
A function for ascorbic acid in the metabolism of an insect.
Topics: Ascorbic Acid; Folic Acid; Glutathione; Insecta; Pyridoxal Phosphate; Tyrosine; Vitamins | 1960 |
A method of determining pyridoxal phosphate in blood by decarboxylation of L-tyrosine-14C (U).
Topics: Blood Chemical Analysis; Decarboxylation; Humans; Pyridoxal Phosphate; Tyrosine; Tyrosine Decarboxylase | 1962 |
[ON TYROSINE METABOLISM IN INSECTS. XII. PURIFICATION, PROPERTIES AND SUBSTRATE SPECIFICITY OF DOPA-DECARBOXYLASE].
Topics: Animals; Biochemical Phenomena; Chromatography; Dihydroxyphenylalanine; Dopa Decarboxylase; Insecta; Iron; Proteins; Pyridoxal Phosphate; Research; Substrate Specificity; Tyrosine | 1963 |
KINETIC STUDIES ON TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE. ORDER OF ADDITION OF SUBSTRATES AND MODE OF INTERACTION OF THYROXINE AND 3,5,3'-TRIIODOTHYRONINE.
Topics: Chemistry Techniques, Analytical; Enzyme Inhibitors; Ketoglutaric Acids; Kinetics; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Research; Thyroxine; Transaminases; Triiodothyronine; Tyrosine; Tyrosine Transaminase | 1963 |
THE COFACTOR-MEDIATED REGULATION OF APOENZYME LEVELS IN ANIMAL TISSUES. I. THE PYRIDOXINE-INDUCED RISE OF RAT LIVER TYROSINE TRANSAMINASE LEVEL IN VIVO.
Topics: Adrenalectomy; Animals; Anti-Bacterial Agents; Antimetabolites; Apoenzymes; Cortisone; Dactinomycin; Dermatologic Agents; Liver; Liver Extracts; Pharmacology; Proteins; Puromycin; Pyridoxal Phosphate; Pyridoxine; Rats; Research; Transaminases; Tyrosine; Tyrosine Transaminase | 1963 |
COMPARATIVE INVESTIGATION ON TYROSINE METABOLISM IN ANIMALS.
Topics: Acetoacetates; Amino Acids; Animals; Anura; Birds; Fishes; Fumarates; Gentisates; Manometry; Oxidoreductases; Physiology, Comparative; Pyridoxal Phosphate; Rats; Reptiles; Research; Snails; Transaminases; Tyrosine; Tyrosine Transaminase | 1965 |
[Synthesis of tyrosine-codecarboxylase by phosphokinase of yeast].
Topics: Pyridoxal Phosphate; Saccharomyces cerevisiae; Thiamine Pyrophosphate; Tyrosine; Yeast, Dried; Yeasts | 1951 |
[Enzymatic synthesis of cocarboxylase and of tyrosine codecarboxylase by yeast phosphokinases].
Topics: Lyases; Pyridoxal Phosphate; Saccharomyces cerevisiae; Thiamine Pyrophosphate; Tyrosine; Yeast, Dried; Yeasts | 1951 |
Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction.
Topics: beta-Alanine; Binding Sites; Butyrates; Carbon-Carbon Lyases; Catalysis; Crystallization; Crystallography, X-Ray; Cyclopropanes; Diamines; Enzyme Inhibitors; Glycine; Mutagenesis, Site-Directed; Pichia; Pseudomonas; Pyridoxal Phosphate; Structural Homology, Protein; Substrate Specificity; Tyrosine | 2004 |
Determinants of substrate specificity in omega-aminotransferases.
Topics: Amino Acids; Aminobutyrates; Binding Sites; Biochemistry; Crystallography, X-Ray; Deuterium; DNA; Glutamic Acid; Humans; Isoleucine; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate; Recombinant Fusion Proteins; Spectrophotometry; Substrate Specificity; Time Factors; Transaminases; Tyrosine | 2005 |
Probing the role of Tyr 64 of Treponema denticola cystalysin by site-directed mutagenesis and kinetic studies.
Topics: Animals; Base Sequence; Cystathionine gamma-Lyase; DNA Primers; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Treponema denticola; Tyrosine | 2005 |
A multifactorial design for studying factors influencing growth and tyramine production of the lactic acid bacteria Lactobacillus brevis CECT 4669 and Enterococcus faecium BIFI-58.
Topics: Culture Media; Enterococcus faecium; Hydrogen-Ion Concentration; Levilactobacillus brevis; Linear Models; Pyridoxal Phosphate; Temperature; Time Factors; Tyramine; Tyrosine | 2006 |
The use of the tyrosine apodecarboxylase of Streptococcus faecalis R for the estimation of codecarboxylase.
Topics: Enterococcus faecalis; Enzymes; Pyridoxal Phosphate; Tyrosine | 1949 |
Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions.
Topics: Apoenzymes; Arginine; Binding Sites; Catalysis; Citrobacter freundii; Crystallography, X-Ray; Enzyme Activation; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Phenylalanine; Potassium; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Novel inhibitors of glycation and AGE formation.
Topics: Animals; Ascorbic Acid; Body Weight; Butyrates; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dyslipidemias; Glycation End Products, Advanced; Glycosylation; Hydroxyl Radical; Hypoglycemic Agents; Kidney; Lipid Metabolism; Lipoproteins, LDL; Male; Molecular Structure; Oxidation-Reduction; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Triglycerides; Tyrosine | 2007 |
Effect of PPADS on achondroplasic chondrocytes: inhibition of FGF receptor type 3 over-activity.
Topics: Achondroplasia; Animals; Cell Line; Cell Survival; Chondrocytes; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix; Fibroblast Growth Factor 9; Humans; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Protein Kinase Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Purinergic P2; Signal Transduction; Time Factors; Transfection; Tyrosine | 2008 |
An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme.
Topics: Animals; Apoenzymes; Bacterial Proteins; Catalytic Domain; Cystathionine gamma-Lyase; Escherichia coli; Holoenzymes; Kinetics; Leucine; Lyases; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Quaternary; Pyridoxal Phosphate; Structure-Activity Relationship; Treponema denticola; Tyrosine | 2009 |
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Tyrosine | 2008 |
Pyridoxal phosphate-responsive seizures in a patient with cerebral folate deficiency (CFD) and congenital deafness with labyrinthine aplasia, microtia and microdontia (LAMM).
Topics: Base Sequence; Child; Codon, Nonsense; Congenital Abnormalities; Congenital Microtia; Dihydroxyphenylalanine; DNA Primers; Ear; Ear, Inner; Electroencephalography; Epilepsy; Fibroblast Growth Factor 3; Folate Receptor 1; Folic Acid Deficiency; Humans; Levodopa; Male; Molecular Sequence Data; Pyridoxal Phosphate; Radiography; Sequence Analysis, DNA; Skull; Syndrome; Tooth Abnormalities; Tyrosine | 2011 |
Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Folic Acid; Hyperalgesia; Male; Nerve Fibers; Neural Conduction; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyridoxal Phosphate; Rats; Rats, Zucker; Sciatic Nerve; Tibial Nerve; Tyrosine; Vitamin B 12 | 2012 |
Quantum chemistry studies of the catalysis mechanism differences between the two isoforms of glutamic acid decarboxylase.
Topics: Biocatalysis; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Isoenzymes; Kinetics; Lysine; Protein Structure, Secondary; Protons; Pyridoxal Phosphate; Quantum Theory; Thermodynamics; Tyrosine | 2013 |
Three different classes of aminotransferases evolved prephenate aminotransferase functionality in arogenate-competent microorganisms.
Topics: Amino Acids, Dicarboxylic; Bacteria; Bacterial Proteins; Cyclohexenes; Evolution, Molecular; Humans; Pyridoxal Phosphate; Transaminases; Tyrosine | 2014 |
Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate.
Topics: Binding Sites; Biocatalysis; Catalytic Domain; Hydro-Lyases; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Mutation, Missense; Nitrogen; Protein Binding; Proteins; Pyridines; Pyridoxal Phosphate; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Spectrophotometry; Tyrosine; Zinc | 2014 |
The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures.
Topics: Amino Acid Sequence; Apoenzymes; Archaeal Proteins; Asparagine; Catalytic Domain; Dimerization; Glycine Hydroxymethyltransferase; Holoenzymes; Hot Temperature; Ligands; Methanocaldococcus; Models, Molecular; Mutant Proteins; Protein Conformation; Protein Interaction Domains and Motifs; Protein Stability; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Tyrosine | 2014 |
Role of active-site residues Tyr55 and Tyr114 in catalysis and substrate specificity of Corynebacterium diphtheriae C-S lyase.
Topics: Biocatalysis; Catalytic Domain; Circular Dichroism; Corynebacterium diphtheriae; Hydrogen-Ion Concentration; Kinetics; Lyases; Molecular Dynamics Simulation; Mutant Proteins; Pyridoxal Phosphate; Spectrometry, Fluorescence; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2015 |
Pyridoxal in the Cerebrospinal Fluid May Be a Better Indicator of Vitamin B6-dependent Epilepsy Than Pyridoxal 5'-Phosphate.
Topics: 5-Hydroxytryptophan; Adolescent; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Pipecolic Acids; Pyridoxal; Pyridoxal Phosphate; Retrospective Studies; Tyrosine; Vitamin B 6; Young Adult | 2020 |
O-Acetylhomoserine Sulfhydrylase from Clostridioides difficile: Role of Tyrosine Residues in the Active Site.
Topics: Catalytic Domain; Clostridioides; Clostridioides difficile; Cysteine Synthase; Kinetics; Methionine; Pyridoxal Phosphate; Tyrosine | 2023 |