pyridoxal phosphate has been researched along with suramin in 215 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.47) | 18.7374 |
| 1990's | 68 (31.63) | 18.2507 |
| 2000's | 116 (53.95) | 29.6817 |
| 2010's | 29 (13.49) | 24.3611 |
| 2020's | 1 (0.47) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Buda, E; Pollard, HB; Shulman, NR; Tack-Goldman, K | 1 |
| Bäumert, HG; Breddin, HK; Lambrecht, G; Mutschler, E; Radziwon, P; Windscheif, U | 1 |
| Buell, G; Evans, RJ; Lewis, C; North, RA; Surprenant, A; Valera, S | 1 |
| Galligan, JJ; Harpstead, T; Herring, A | 1 |
| Bennett, MR; Motin, L | 1 |
| Hollingsworth, M; Piper, AS | 2 |
| Andréola, ML; Litvak, S; Tarrago-Litvak, L; Tharaud, D | 1 |
| Boyer, JL; Harden, TK; Jacobson, KA; Zohn, IE | 1 |
| Humphrey, PP; Khakh, BS; Michel, A | 1 |
| Humphrey, PP; Kennedy, I; Trezise, DJ | 1 |
| Bindokas, V; Brorson, JR; Macdonald, RL; Marton, LS; Miller, RJ; Weir, B; Zhang, H | 1 |
| Buell, G; Collo, G; Lewis, C; North, RA; Surprenant, A | 1 |
| Furukawa, T; Katsuragi, T; Usune, S | 1 |
| Hicks, J; Ho, C; Salter, MW | 1 |
| Fredholm, BB; Jiang, S; Kull, B; Orrenius, S | 1 |
| Boarder, MR; Brown, CA; Charlton, SJ; Erb, L; Turner, JT; Weisman, GA | 2 |
| Dale, N; Gilday, D | 1 |
| Nakamura, F; Strittmatter, SM | 1 |
| Burnstock, G; Rubino, A | 1 |
| Burnstock, G; Knight, GE | 1 |
| Macdonald, L; Marton, LS; Sima, B; Weir, B; Zhang, J | 1 |
| Giachetti, A; Maggi, CA; Santicioli, P; Zagorodnyuk, V | 1 |
| Bültmann, R; Dudeck, O; Starke, K | 1 |
| Castro, E; Mateo, J; Miras-Portugal, MT | 1 |
| Grahames, CB; Humphrey, PP; Michel, AD | 1 |
| Cook, AK; Inscho, EW; Navar, LG | 1 |
| Barajas-López, C; Collins, SM; Espinosa-Luna, R; Gerzanich, V; Huizinga, JD; Peres, AL | 1 |
| Chen, BC; Lee, CM; Lin, WW | 1 |
| Burnstock, G; Ren, LM | 1 |
| Cazenave, JP; Gachet, C; Hechler, B; Léon, C; Leray, C; Vial, C | 1 |
| Babenko, AP; Vassort, G | 1 |
| Lambrecht, G | 2 |
| Boarder, MR; Brown, CA; Charlton, SJ | 1 |
| Bowes, J; Kennedy, C; McIntyre, CA; Obeid, S; Sneddon, P; Westfall, TD | 1 |
| Boeynaems, JM; Communi, D; Robaye, B | 1 |
| Comer, AM; Funk, GD; Housley, GD; Kanjhan, R; Lipski, J; Parkis, MA; Walsh, C | 1 |
| Di Virgilio, F; Falzoni, S; Galietta, LJ; Romeo, G; Zegarra-Moran, O | 1 |
| Reid, A; Sawynok, J | 1 |
| Barthó, L; Lénárd, L; Maggi, CA | 1 |
| Cheng, JT; Hung, YC; Kunitomo, M; Shinozuka, K; Tong, YC | 1 |
| Macdonald, RL; Sima, B; Weir, BK; Zhang, H | 1 |
| Illes, P; Nieber, K; Poelchen, W | 1 |
| Candura, SM; D'Agostino, G; Di Nucci, A; Fiori, E; Franceschetti, GP; Ricotti, P; Tagliani, M; Tonini, M | 1 |
| Brodie, MJ; Ross, FM; Stone, TW | 1 |
| Maggi, CA; Zagorodnyuk, V | 1 |
| Buchanan, KJ; Burke, KS; Kennedy, C; McLaren, GJ; Sneddon, P | 1 |
| Kennedy, C; Rae, MG; Rowan, EG | 1 |
| Li, C; Peoples, RW | 1 |
| Kennedy, C; McLaren, GJ; Sneddon, P | 1 |
| Burnstock, G; Pinna, C; Puglisi, L | 1 |
| Boehm, S | 1 |
| Babinski, K; Lê, KT; Séguéla, P | 1 |
| Bardoni, R; Gu, JG; MacDermott, AB; Magherini, PC | 1 |
| Ito, S; Nakazato, Y; Ohta, T; Otsuguro, K | 1 |
| Bo, X; Burnstock, G; Dunn, PM; Xiang, Z; Zhong, Y | 1 |
| Evans, RJ; Grubb, BD | 1 |
| Hofmann, HD; Sugioka, M; Yamashita, M; Zhou, WL | 1 |
| Castro, E; Delicado, EG; García-Lecea, M; Miras-Portugal, MT | 1 |
| Bültmann, R; Starke, K; Trendelenburg, M; Tuluc, F; Wittenburg, H | 1 |
| Bloom, BR; Brosnan, C; Buell, G; Chessel, I; Liu, J; Sikora, A | 1 |
| Anning, PB; Buss, DC; Lewis, MJ; MacCarthy, PA; Prendergast, BD; Shah, AM | 1 |
| Cinkilic, O; Jankowski, J; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W | 1 |
| Barthó, L; Heinemann, A; Holzer, P; Shahbazian, A | 1 |
| Booth, CE; Chessell, IP; Grundy, D; Humphrey, PP; Kirkup, AJ | 1 |
| Matsuyama, H; Takewaki, T; Thapaliya, S | 1 |
| Nishi, H | 1 |
| Fukumitsu, A; Honda, K; Iki, A; Kamiya, H; Katsuragi, T; Saito, R; Takano, Y | 1 |
| Burnstock, G; Dunn, PM; Zhong, Y | 2 |
| Dixon, CJ; Green, AK; Webb, TE; Woods, NM | 1 |
| Dickenson, AH; Kontinen, VK; Stanfa, LC | 1 |
| Barnard, EA; Chessell, IP; Humphrey, PP; Jones, CA; Michel, AD; Miller, KJ; Simon, J | 1 |
| Spyer, KM; Thomas, T | 1 |
| Barnes, AP; Bobbin, RP; Chen, C; Deininger, P; Parker, MS | 1 |
| Kennedy, C; Nickel, P; Sneddon, P; Todorov, LD; Todorova, SM; Westfall, DP; Westfall, TD | 1 |
| Burnstock, G; Rong, W; Spyer, KM | 1 |
| Ebisawa, T; Hayashida, K; Kawamura, M; Kondo, I; Masaki, E; Matsumoto, Y | 1 |
| Burnstock, G; Yegutkin, GG | 1 |
| Liu, T; Tracey, DJ | 1 |
| Bäumert, HG; Braun, K; Ganso, M; Hildebrandt, C; Lambrecht, G; Mutschler, E; Spatz-Kümbel, G | 1 |
| Li, C; Weight, FF; Xiong, K | 1 |
| Ferreira, ZS; Markus, RP; Mortani Barbosa, EJ | 1 |
| Ennion, SJ; Evans, RJ; Lewis, CJ | 1 |
| Carolan, BM; Harden, TK; Keef, KD; Mutafova-Yambolieva, VN | 1 |
| Dohi, T; Fukuhara, N; Imai, Y; Kitayama, S; Morita, K; Sakakibara, A; Tanne, K | 1 |
| Cunha, RA; Hernández, MD; Miras-Portugal, MT; Pereira, MF; Pintor, J; Ribeiro, JA | 1 |
| Bagnol, D; Galligan, JJ; Ishiguchi, T; LePard, K; Mizuta, Y; Owyang, C; Schneider, D; Takahashi, T; Watson, SJ | 1 |
| Bertrand, PP; Bian, X; Bornstein, JC | 1 |
| Boarder, MR; Kumari, R; London, NJ; Ng, LL; Porter, KE; White, PJ | 1 |
| O'Kane, EM; Stone, TW | 1 |
| Keef, KD; Mutafova-Yambolieva, VN | 1 |
| Evans, RJ; Lewis, CJ | 1 |
| Dacey, RG; Dietrich, HH; Horiuchi, T; Tsugane, S | 1 |
| Ralevic, V | 1 |
| Boeynaems, J; Pouillon, V; Robaye, B; Suarez-Huerta, N | 1 |
| Bültmann, R; Starke, K | 1 |
| Akaike, N; Ishibashi, H; Moritoyo, T; Sorimachi, M | 1 |
| Fischer, KG; Jacobshagen, C; Pavenstädt, H; Saueressig, U; Wichelmann, A | 1 |
| Gorodeski, GI | 1 |
| Jiang, LH; North, RA; Spelta, V; Surprenant, A | 1 |
| Bianchi, B; Cartmell, J; Faltynek, C; Honore, P; Jarvis, MF; McDonald, H; Mikusa, J | 1 |
| Gourine, AV; Gourine, VN; Melenchuk, EV; Poputnikov, DM; Spyer, KM | 1 |
| Funk, GD; Lipski, J; Miles, GB; Parkis, MA | 1 |
| Kimura, J; Matsuoka, I; Watano, T | 1 |
| Sorimachi, M; Wakomori, M; Yamagami, K | 1 |
| Bertrand, PP; Bornstein, JC | 1 |
| Badr, A; Kimura, H; Meguro, T; Zhang, JH | 1 |
| Katayama, T; Kawaguchi, N; Minami, M; Nakagawa, T; Nakamura, J; Ohtani, Y; Satoh, M; Yamakuni, H | 1 |
| Boscan, P; De Paula, PM; Machado, BH; Paton, JF; Spyer, KM | 1 |
| Braun, K; Damer, M; Ganso, M; Hildebrandt, C; Kassack, MU; Lambrecht, G; Nickel, P; Ullmann, H | 1 |
| Laube, B | 1 |
| Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
| Denda, M; Denda, S; Fuziwara, S; Inoue, K | 1 |
| Hoyle, CH; Martín, S; Peláez, T; Peral, A; Pintor, J | 1 |
| Borchardt, K; Krause, U; Ruppelt, A; Soto, F | 1 |
| Hashimoto, M; Kawasaki, K; Kubota, Y; Kunitomo, M; Nakamura, K; Shinozuka, K; Tanaka, N | 1 |
| Furuya, K; Kiyohara, T; Okuda, A | 1 |
| Alloisio, S; Cugnoli, C; Ferroni, S; Monaldi, I; Nobile, M | 1 |
| Darby, M; Feighan, D; Kuzmiski, JB; MacVicar, BA; Panenka, W | 1 |
| Laubinger, W; Reiser, G; Wang, H; Welte, T | 1 |
| Gallagher, CJ; Salter, MW | 1 |
| Bringmann, A; Francke, M; Goczalik, I; Pannicke, T; Reichenbach, A; Uckermann, O; Uhlmann, S; Ulbricht, E; Weick, M; Wiedemann, P | 1 |
| Allen, DG; Barden, JA; Huang, W; Jiang, L; Ju, YK | 1 |
| Fujihara, T; Murakami, T; Nakamura, M; Nakata, K | 1 |
| Kawa, K | 1 |
| De Man, JG; De Schepper, HU; De Winter, BY; Herman, AG; Pelckmans, PA; Seerden, TC | 1 |
| Krishtal, O; Lalo, U; Pankratov, Y; Verkhratsky, A | 1 |
| Alvarez-Barrientos, A; Barrachina, MD; Esplugues, JV; Hernández, C; Quintana, E | 1 |
| Hori, S; Kawamura, M; Masaki, E; Yamazaki, K | 1 |
| Antunes, VR; Bonagamba, LG; de Paula, PM; Machado, BH | 1 |
| Li, C; Stewart, RR; Weight, FF; Xiong, K | 1 |
| Arai, AC; Kessler, M; Montgomery, K; Suzuki, E | 1 |
| Fanò, G; Guarnieri, S; Mariggiò, MA; Rathbone, MP | 1 |
| Atterbury-Thomas, AE; Calvert, JA; Evans, RJ; Forsythe, ID; Gachet, C; Leon, C | 1 |
| Boehm, S; Dorostkar, MM; Edelbauer, H; Lechner, SG; Mayer, M; Pankevych, H | 1 |
| Bennett, MR; Lin, YQ | 1 |
| Bennett, MR; Liu, GJ; Werry, EL | 1 |
| Mikhutkina, SV; Olovyannikova, RY; Popova, NN; Salmina, AB; Taksanova, EI; Uspenskaya, YA | 1 |
| Burnstock, G; Grishin, SN; Kamaliev, RR; Zefirov, AL; Ziganshin, AU; Ziganshina, LE | 1 |
| Jacobson, KA; Shainberg, A; Shneyvays, V; Yitzhaki, S | 1 |
| Acuna-Goycolea, C; van den Pol, AN; Wollmann, G | 1 |
| Gerstberger, R; Gourine, AV; Gourine, VN; Melenchuk, EV; Poputnikov, DM; Spyer, KM; Zhernosek, N | 1 |
| Almeida, T; Cunha, RA; Oliveira, CR; Richardson, PJ; Rodrigues, RJ | 1 |
| Boudaka, A; Draid, M; El-Mahmoudy, A; Shiina, T; Shimizu, Y; Takewaki, T | 1 |
| Poletto Chaves, LA; Pontelli, EP; Varanda, WA | 1 |
| Kang, TC; Kim, DS; Kim, JE; Kwak, SE; Oh, YS; Suh, JG; Won, MH | 1 |
| Ding, W; Granstein, RD; Seiffert, K; Wagner, JA | 1 |
| Kinoshita, N; Mizuno, N; Shinozuka, K; Tada, S; Takahashi, K; Takahashi, T | 1 |
| Fujita, Y; Honda, M; Ishikawa, T; Koganezawa, T; Nakayama, K; Tajima, T; Yamashita, T | 1 |
| Joshi, PG; Lakshmi, S | 1 |
| Ellefsen, S; Hafting, T; Haug, TM; Sand, O | 1 |
| Kang, TC; Kim, DS; Kim, JE; Kwak, SE; Won, MH | 1 |
| Draid, M; El-Mahmoudy, A; Khalifa, M; Shiina, T; Shimizu, Y; Takewaki, T | 1 |
| Arnold, A; Brandt, A; Milosevic, J; Roemuss, U; Schwarz, J; Schwarz, SC; Storch, A; Wegner, F; Zimmermann, H | 1 |
| Antal, A; Barthó, L; Benkó, R; Csontos, Z; Horváth, OP; Illényi, L; Undi, S; Vereczkei, A; Wolf, M | 1 |
| Gallacher, G; Kennedy, C; Tasker, PN; Westfall, TD | 1 |
| Alexander, SP; Latif, ML; Ralevic, V; Rayment, SJ | 1 |
| Housley, GD; Soeller, C; Thorne, PR; Vlajkovic, SM; Wang, CJ; Zimmermann, H | 1 |
| Lalo, U; North, RA; Pankratov, Y; Verkhratsky, A | 1 |
| Britto, LR; Gomes, KN; Majumder, P; Resende, RR; Ulrich, H | 1 |
| Bowser, DN; Khakh, BS | 1 |
| Antal, A; Barthó, L; Benkó, R; Cseke, L; Horváth, OP; Illényi, L; Kassai, M; Kelemen, D; Magyar, K; Undi, S; Vereczkei, A; Wolf, M | 1 |
| Li, L; Wingo, CS; Xia, SL | 1 |
| Groulx, N; Grygorczyk, R; Orlov, SN; Tatur, S | 1 |
| Boknik, P; Gergs, U; Neumann, J; Schmitz, W; Silber, RE; Simm, A | 1 |
| Croxatto, JO; Gallo, JE; Kvanta, A; Mancini, J; Sarman, S; van der Ploeg, I | 1 |
| Custer, EE; Knott, TK; Lemos, JR; Marrero, HG | 1 |
| Yu, N; Zhao, HB | 1 |
| Betto, R; Danieli-Betto, D; Esposito, A; Germinario, E; Midrio, M; Palade, PT; Peron, S | 1 |
| Poletto Chaves, LA; Varanda, WA | 1 |
| Davies, DL; Li, K; Xiao, C; Ye, JH; Zhou, C | 1 |
| Kadowaki, M; Leng, Y; Yamamoto, T | 1 |
| Kim, DR; Kong, ID; Lee, DH; Lee, JW; Park, KS | 1 |
| Chow, JY; Dong, H; Dong, X; Insel, PA; Kim, HD; Ko, KH; Lee, J; Smoll, EJ | 1 |
| Hegg, CC; Jia, C; Kanekar, S | 1 |
| Cho, H; Choi, YM; Chung, S; Jang, JY; Jang, M; Kang, YK; Kim, SH; Park, MK | 1 |
| Aschenbach, KL; Crumling, MA; Duncan, RK; Liu, LQ; Pipitone, CM; Tong, M | 1 |
| Hattori, T; Ichinose, M; Kikuchi, T; Kume, H; Moriya, T; Nagaoka, M; Nara, M; Oguma, T; Tamada, T; Tamura, G; Zaini, J | 1 |
| Grace, AA; Gurung, IS; Huang, CL; Kalin, A | 1 |
| Barajas-López, C; Espinosa-Luna, R; Guerrero-Alba, R; Juárez, EH; Miranda-Morales, M; Ramírez-Martínez, JF; Valdez-Morales, E | 1 |
| Durai, L; Ennion, SJ; Ludlow, MJ | 1 |
| Bult, H; Fransen, P; Guns, PJ; Hendrickx, J; Van Assche, T | 1 |
| Hegg, CC; Jia, C; Roman, C | 1 |
| Sato, A; Shitara, A; Tanimura, A; Tojyo, Y | 1 |
| Burnstock, G; Cao, L; Gao, L; He, C; Qiu, Y; Su, Z; Xiang, Z | 1 |
| Andersson, M; Aronsson, P; Ericsson, T; Giglio, D | 1 |
| Aure, MH; Galtung, HK; Røed, A | 1 |
| Ito, S; Lu, J; Matsumura, S; Naritsuka, H; Okuda-Ashitaka, E; Takagi, K; Yamaguchi, M | 1 |
| Huang, T; Jankowski, J; Jankowski, V; Klöckel, L; Schuchardt, M; Tölle, M; van der Giet, M; Wiedon, A; Zidek, W | 1 |
| Kréneisz, O; Mulkey, DK; Nishiyama, A; Wenker, IC | 1 |
| Karaki, S; Kuwahara, A | 1 |
| Barajas-López, C; Carbajal, V; Checa, M; Figueroa, A; Flores-Soto, E; García-Hernández, LM; Montaño, LM; Reyes-García, J | 1 |
| Barbosa, SP; De Andrade, CA; De Paula, PM; Menani, JV; Menezes, MF | 1 |
| Schnermann, J | 1 |
| Angielski, S; Jankowski, M; Karczewska, J; Piwkowska, A; Rogacka, D; Stępiński, J | 1 |
| Han, Z; Taylor, JM | 1 |
| Cronin, C; Edwards, TM; Gibbs, ME | 1 |
| Figueroa, JD; Miranda, JD; Rodríguez-Zayas, AE; Rosas, OR; Santiago, JM; Torrado, AI | 1 |
| Asada, K; Horiguchi, K; Obata, K; Takaki, M | 1 |
| Cuadra, AE; Custer, EE; Knott, TK; Lemos, JR; Ortiz-Miranda, S | 1 |
| Moreira, TS; Mulkey, DK; Sobrinho, CR; Takakura, AC; Wenker, IC | 1 |
| Burnstock, G; Crawford, C; Elliott, J; Fordham, AF; Janska, SE; Knight, GE; Peppiatt-Wildman, CM; Wildman, SS; Zerpa, H | 1 |
| Cao, Q; Dong, XP; Huang, P; Murrell-Lagnado, R; Zhao, K; Zhong, XZ; Zhu, MX; Zou, Y | 1 |
| Harada, H; Ishimaru, M; Kitani, H; Kojima, S; Takenouchi, T; Tsukimoto, M; Yusuke, N | 1 |
| Clavé, P; Gallego, D; Gil, V; Jiménez, M; Mañé, N; Martín, MT; Martínez-Cutillas, M | 1 |
| Abramochkin, DV; Kuzmin, VS; Pustovit, KB | 1 |
| Akcan, U; Erten, G; Giriş, M; Örçen, A; Tüzün, E; Yilmaz, V | 1 |
| Cabral, LDM; Giusti-Paiva, A; Teodoro, LC; Vilela, FC | 1 |
| Caringal, H; Gongwer, M; Heer, C; Jacoby, J; Kaufman, R; Kreitzer, MA; Malchow, RP; Shepherd, L; Swygart, D; Tchernookova, BK; Young, M | 1 |
| Hamaguchi, S; Kariya, M; Namekata, I; Ozaki, AF; Tanaka, H | 1 |
4 review(s) available for pyridoxal phosphate and suramin
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
Design and pharmacology of selective P2-purinoceptor antagonists.
Topics: Animals; Guinea Pigs; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Rats; Suramin; Vas Deferens | 1996 |
Agonists and antagonists acting at P2X receptors: selectivity profiles and functional implications.
Topics: Animals; Humans; Ligands; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 2000 |
Structure-activity relationships of suramin and pyridoxal-5'-phosphate derivatives as P2 receptor antagonists.
Topics: Animals; Humans; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin | 2002 |
211 other study(ies) available for pyridoxal phosphate and suramin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A new class of drugs that inhibit platelet release and aggregation.
Topics: Anions; Biological Transport; Blood Platelets; Exocytosis; Furosemide; Hydrogen-Ion Concentration; Osmolar Concentration; Platelet Aggregation; Probenecid; Pyridoxal Phosphate; Serotonin; Sulfinpyrazone; Suramin; Thrombin | 1978 |
Two different inhibitory effects of pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid on adenosine diphosphate-induced human platelet aggregation.
Topics: Adenosine Diphosphate; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin | 1995 |
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2x purinoceptors).
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenine Nucleotides; Adenosine Triphosphate; Animals; Cell Line; Cloning, Molecular; DNA, Complementary; Humans; Ion Channel Gating; Ion Channels; PC12 Cells; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Suramin | 1995 |
Pharmacological characterization of purinoceptor-mediated constriction of submucosal arterioles in guinea pig ileum.
Topics: Adenosine Triphosphate; Animals; Arterioles; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; Intestinal Mucosa; Nifedipine; Purinergic Agonists; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Vasoconstrictor Agents | 1995 |
Effect of P2-purinoceptor antagonists on glutamatergic transmission in the rat hippocampus.
Topics: Animals; Glutamates; Hippocampus; In Vitro Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Triazines | 1995 |
The purinoceptors of the guinea-pig isolated taenia caeci.
Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Theophylline | 1995 |
The ribonuclease H activity of HIV-1 reverse transcriptase: further biochemical characterization and search of inhibitors.
Topics: Benzodiazepines; Biopolymers; Ethylmaleimide; HIV Reverse Transcriptase; HIV-1; Imidazoles; Nucleic Acid Synthesis Inhibitors; Phosphonoacetic Acid; Pyridoxal Phosphate; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Suramin | 1993 |
Differential effects of P2-purinoceptor antagonists on phospholipase C- and adenylyl cyclase-coupled P2Y-purinoceptors.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Erythrocyte Membrane; Glioma; Protein Synthesis Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Suramin; Triazines; Turkeys; Type C Phospholipases | 1994 |
Estimates of antagonist affinities at P2X purinoceptors in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Congo Red; Glutathione Transferase; Male; Muscle Contraction; Naphthalenesulfonates; Purinergic Antagonists; Pyridoxal Phosphate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin; Triazines; Trypan Blue; Vas Deferens | 1994 |
The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by alpha, beta-methylene adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Animals; Electrophysiology; In Vitro Techniques; Kinetics; Male; Neuromuscular Depolarizing Agents; Protein Synthesis Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Triazines; Vagus Nerve | 1994 |
Mechanisms of hemolysate-induced [Ca2+]i elevation in cerebral smooth muscle cells.
Topics: 2,3-Diphosphoglycerate; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cytosol; Diphosphoglyceric Acids; Female; Hemolysis; Homeostasis; Muscle, Smooth, Vascular; Nucleotides; Osmolar Concentration; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Suramin | 1995 |
An antagonist-insensitive P2X receptor expressed in epithelia and brain.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Brain; Cloning, Molecular; DNA, Complementary; Epithelium; Gene Expression; Lysine; Molecular Sequence Data; Oligonucleotides; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; RNA, Messenger; Salivary Glands; Sequence Alignment; Sequence Homology, Amino Acid; Signal Transduction; Structure-Activity Relationship; Suramin | 1996 |
Effects of PPADS and suramin on contractions and cytoplasmic Ca2+ changes evoked by AP4A, ATP and alpha, beta-methylene ATP in guinea-pig urinary bladder.
Topics: Adenosine Triphosphate; Calcium; Calcium Channel Blockers; Cytoplasm; Dinucleoside Phosphates; In Vitro Techniques; Muscle Contraction; Nifedipine; Pyridoxal Phosphate; Suramin; Urinary Bladder | 1996 |
A novel P2-purinoceptor expressed by a subpopulation of astrocytes from the dorsal spinal cord of the rat.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium; Carbachol; Cells, Cultured; Drug Interactions; Pertussis Toxin; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Spinal Cord; Suramin; Thionucleotides; Uridine Triphosphate; Virulence Factors, Bordetella | 1995 |
P2-purinoceptors mediating spasm of the isolated uterus of the non-pregnant guinea-pig.
Topics: Adenosine Triphosphate; Animals; Female; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spasm; Suramin; Theophylline; Thioinosine; Thionucleotides; Uridine Triphosphate; Uterus | 1996 |
P2x purinoceptor is not important in thymocyte apoptosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Base Sequence; DNA Primers; Molecular Sequence Data; Purinergic Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin; Thymus Gland | 1996 |
PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors.
Topics: Cell Line; Dose-Response Relationship, Drug; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin; Transfection; Uridine Triphosphate | 1996 |
Regulation of rhythmic movements by purinergic neurotransmitters in frog embryos.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Culture Techniques; Embryo, Nonmammalian; Glutamic Acid; Ion Channel Gating; Motor Neurons; Movement; N-Methylaspartate; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P1; Receptors, Purinergic P2; Spinal Cord; Suramin; Swimming; Synapses; Theophylline; Xenopus | 1996 |
P2Y1 purinergic receptors in sensory neurons: contribution to touch-induced impulse generation.
Topics: Adenosine Triphosphate; Animals; Apyrase; Chickens; Female; Ganglia, Spinal; Membrane Potentials; Molecular Sequence Data; Nerve Fibers; Neurons, Afferent; Oocytes; Physical Stimulation; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; RNA, Messenger; Sciatic Nerve; Skin; Suramin; Time Factors; Transcription, Genetic; Xenopus laevis | 1996 |
Evidence for a P2-purinoceptor mediating vasoconstriction by UTP, ATP and related nucleotides in the isolated pulmonary vascular bed of the rat.
Topics: Adenosine Triphosphate; Animals; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Pulmonary Circulation; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Uridine Triphosphate; Vasoconstriction | 1996 |
The effects of purine compounds on the isolated aorta of the frog Rana temporaria.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Pyridoxal Phosphate; Rana temporaria; Receptors, Purinergic; Suramin; Uridine Triphosphate; Vasoconstriction; Vasodilation | 1996 |
Effect of P2-purinoceptor antagonists on hemolysate-induced and adenosine 5'-triphosphate-induced contractions of dog basilar artery in vitro.
Topics: Adenosine Triphosphate; Animals; Basilar Artery; Dogs; Female; Hemolysis; Ischemic Attack, Transient; Male; Muscle, Smooth, Vascular; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Subarachnoid Hemorrhage; Suramin | 1996 |
The possible role of ATP and PACAP as mediators of apaminsensitive NANC inhibitory junction potentials in circular muscle of guinea-pig colon.
Topics: Adenosine Triphosphate; Animals; Apamin; Colon; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyridoxal Phosphate; Receptors, Adrenergic; Receptors, Cholinergic; Suramin; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Evaluation of P2-purinoceptor antagonists at two relaxation-mediating P2-purinoceptors in guinea-pig taenia coli.
Topics: Adrenergic alpha-Agonists; Animals; Carbachol; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male; Muscle Relaxation; Norepinephrine; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 1996 |
Co-existence of P2Y-and PPADS-insensitive P2U-purinoceptors in endothelial cells from adrenal medulla.
Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Arachidonic Acid; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 1996 |
Functional characterisation of P2 purinoceptors in PC12 cells by measurement of radiolabelled calcium influx.
Topics: Adenosine Triphosphate; Animals; Antinematodal Agents; Calcium; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Nicotinic Antagonists; PC12 Cells; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Suramin; Temperature; Time Factors; Triazines; Tubocurarine | 1996 |
Pressure-mediated vasoconstriction of juxtamedullary afferent arterioles involves P2-purinoceptor activation.
Topics: Adenosine Triphosphate; Animals; Arterioles; Homeostasis; Humans; Kidney Medulla; Male; Perfusion; Pressure; Purinergic Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Renal Circulation; Suramin; Time Factors; Vasoconstriction | 1996 |
Cloned and transfected P2Y4 receptors: characterization of a suramin and PPADS-insensitive response to UTP.
Topics: Cell Line; Cloning, Molecular; Humans; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Transfection; Uridine Triphosphate | 1996 |
P2x-purinoceptors of myenteric neurones from the guinea-pig ileum and their unusual pharmacological properties.
Topics: Adenosine Triphosphate; Animals; Cell Membrane; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Membrane Potentials; Myenteric Plexus; Neurons; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 1996 |
Inhibition of ecto-ATPase by PPADS, suramin and reactive blue in endothelial cells, C6 glioma cells and RAW 264.7 macrophages.
Topics: Adenosine Triphosphatases; Animals; Brain Neoplasms; Cell Line; Endothelium, Vascular; Enzyme Inhibitors; Glioma; Macrophages; Mice; Phosphatidylinositols; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Suramin; Triazines; Tumor Cells, Cultured | 1996 |
Prominent sympathetic purinergic vasoconstriction in the rabbit splenic artery: potentiation by 2,2'-pyridylisatogen tosylate.
Topics: Adenosine Triphosphate; Adrenergic Agents; Animals; Electric Stimulation; Guanethidine; In Vitro Techniques; Isatin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Receptors, Purinergic P2; Splenic Artery; Suramin; Sympathetic Nervous System; Tetrodotoxin; Vasoconstriction | 1997 |
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Megakaryocytes; Membrane Proteins; Polymerase Chain Reaction; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Suramin | 1997 |
Purinergic facilitation of ATP-sensitive potassium current in rat ventricular myocytes.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Heart Ventricles; Male; Myocardium; Patch-Clamp Techniques; Potassium Channels; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic; Suramin | 1997 |
Enhancement of the response to purinergic agonists in P2Y1 transfected 1321N1 cells by antagonists suramin and PPADS.
Topics: Adenosine Triphosphate; Humans; Inositol Phosphates; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Suramin; Thionucleotides; Transfection; Tumor Cells, Cultured | 1997 |
The interaction of diadenosine polyphosphates with P2x-receptors in the guinea-pig isolated vas deferens.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Analysis of Variance; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Lethal Dose 50; Male; Muscle Contraction; Norepinephrine; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Second Messenger Systems; Suramin; Vas Deferens; Vasoconstrictor Agents | 1997 |
Slow desensitization of the human P2Y6 receptor.
Topics: Adenosine Diphosphate; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Triazines; Tumor Cells, Cultured; Uridine Diphosphate | 1997 |
P2 receptor excitation of rodent hypoglossal motoneuron activity in vitro and in vivo: a molecular physiological analysis.
Topics: Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Antineoplastic Agents; Electrophysiology; Gene Expression; Hypoglossal Nerve; Immunohistochemistry; In Vitro Techniques; Medulla Oblongata; Mice; Motor Neurons; Platelet Aggregation Inhibitors; Polymerase Chain Reaction; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Respiration; Suramin; Vasodilator Agents | 1997 |
Characterization of volume-sensitive taurine- and Cl(-)-permeable channels.
Topics: Adenosine Triphosphate; Antigens, Viral, Tumor; Calcium; Cell Line, Transformed; Chelating Agents; Chloride Channels; Egtazic Acid; Enzyme Inhibitors; Epithelium; Humans; Hypotonic Solutions; Ionomycin; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Pyridoxal Phosphate; Simian virus 40; Suramin; Taurine; Trachea; Triazines | 1997 |
Peripheral adenosine 5'-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Drug Interactions; Male; Nociceptors; Pain Measurement; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Thionucleotides | 1997 |
Evidence for the involvement of P2-purinoceptors in the cholinergic contraction of the guinea-pig ileum.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 1997 |
Evidence of adenosine 5'-triphosphate release from nerve and P2x-purinoceptor mediated contraction during electrical stimulation of rat urinary bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Tetrodotoxin; Urinary Bladder | 1997 |
Extracellular nucleotide-induced [Ca2+]i elevation in rat basilar smooth muscle cells.
Topics: Animals; Basilar Artery; Calcium; Extracellular Space; Female; Fluorometry; Intracellular Membranes; Muscle, Smooth, Vascular; Nucleotides; Osmolar Concentration; Purinergic Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Signal Transduction; Suramin | 1997 |
Role of ATP in fast excitatory synaptic potentials in locus coeruleus neurones of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Locus Coeruleus; Male; Picrotoxin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin | 1997 |
A re-appraisal of the nature of the atropine-resistant contraction to electrical field stimulation in the human isolated detrusor muscle.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Atropine; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Urinary Bladder | 1997 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
Pharmacological evidence for the existence of multiple P2 receptors in the circular muscle of guinea-pig colon.
Topics: Adenosine Diphosphate; Animals; Apamin; Autonomic Nervous System; Colon; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Thionucleotides; Vasodilator Agents | 1998 |
Evidence that ATP acts at two sites to evoke contraction in the rat isolated tail artery.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arteries; Enzyme Inhibitors; Male; Muscle Contraction; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Suramin; Tail | 1998 |
Pharmacological properties of P2X3-receptors present in neurones of the rat dorsal root ganglia.
Topics: Adenosine; Animals; Ganglia, Spinal; Neurons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2X3; Suramin | 1998 |
Inhibition of NMDA-gated ion channels by the P2 purinoceptor antagonists suramin and reactive blue 2 in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Ion Channels; Mice; N-Methylaspartate; Neurons, Afferent; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin; Triazines | 1998 |
Comparison of the actions of ATP and UTP and P(2X1) receptors in smooth muscle of the rat tail artery.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Kinetics; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X; Suramin; Tail; Uridine Triphosphate | 1998 |
ATP and vasoactive intestinal polypeptide relaxant responses in hamster isolated proximal urethra.
Topics: Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Cricetinae; Dinoprostone; Male; Mesocricetus; Muscle Relaxation; Nitric Oxide; Nitroprusside; Pyridoxal Phosphate; Suramin; Triazines; Urethra; Vasoactive Intestinal Peptide | 1998 |
Selective inhibition of M-type potassium channels in rat sympathetic neurons by uridine nucleotide preferring receptors.
Topics: Adenine Nucleotides; Animals; Calcium Channels; Guanine Nucleotides; Hydrolysis; Ion Channel Gating; Neurons; Potassium Channel Blockers; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Suramin; Sympathetic Nervous System; Triazines; Uridine Diphosphate; Uridine Triphosphate | 1998 |
Central P2X4 and P2X6 channel subunits coassemble into a novel heteromeric ATP receptor.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cations; Cells, Cultured; Electrophysiology; Enzyme Inhibitors; Humans; Ion Channel Gating; Kidney; Neuropeptides; Oocytes; Platelet Aggregation Inhibitors; Protons; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Suramin; Triazines; Xenopus laevis; Zinc | 1998 |
Effects of the P2-purinoceptor antagonists suramin and pyridoxal-phosphate-6-azophenyl-2',4'-disulfonic acid on glutamatergic synaptic transmission in rat dorsal horn neurons of the spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Evoked Potentials; Excitatory Postsynaptic Potentials; Glutamates; In Vitro Techniques; Neurons; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Spinal Cord; Suramin; Synaptic Transmission; Time Factors | 1998 |
Two types of relaxation-mediating P2 receptors in rat gastric circular muscle.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Apamin; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Stomach; Suramin; Thionucleotides | 1998 |
Pharmacological and molecular characterization of P2X receptors in rat pelvic ganglion neurons.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Ganglia, Autonomic; Hydrogen-Ion Concentration; Immunohistochemistry; In Situ Hybridization; Male; Membrane Potentials; Neurons; Pelvis; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Time Factors; Triazines; Zinc | 1998 |
Characterization of cultured dorsal root ganglion neuron P2X receptors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Fluorescent Dyes; Ganglia, Spinal; Gene Expression; Ion Channel Gating; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenotype; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; Receptors, Purinergic P2X5; Receptors, Purinergic P2X7; Suramin; Thionucleotides; Uridine Triphosphate | 1999 |
Involvement of P2 purinoceptors in the regulation of DNA synthesis in the neural retina of chick embryo.
Topics: Adenosine Triphosphate; Amniotic Fluid; Animals; Calcium Signaling; Cell Division; Cell Survival; Cells, Cultured; Chick Embryo; DNA Replication; Eye Proteins; Ion Channels; Mitosis; Neurons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Retina; Suramin | 1999 |
P2X2 characteristics of the ATP receptor coupled to [Ca2+]i increases in cultured Purkinje neurons from neonatal rat cerebellum.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Antineoplastic Agents; Calcium Signaling; Cells, Cultured; Cerebellum; Dinucleoside Phosphates; Neuropeptides; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Purkinje Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin | 1999 |
Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anthraquinones; Evans Blue; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Naphthalenes; Naphthalenesulfonates; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2X; Sensitivity and Specificity; Sulfonic Acids; Suramin; Triazines; Trypan Blue; Vas Deferens | 1999 |
Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism.
Topics: Adenosine Triphosphate; Animals; Cell Line; Free Radicals; Macrophage Activation; Macrophages; Mice; Mycobacterium bovis; Mycobacterium tuberculosis; Nitric Oxide; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reactive Oxygen Species; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; Signal Transduction; Suramin | 1999 |
ATP is involved in myocardial and vascular effects of exogenous bradykinin in ejecting guinea pig heart.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Coronary Vessels; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Myocardium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin; Systole; Ventricular Function, Left | 1999 |
Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney.
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney; Male; Perfusion; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic P2; Renal Artery; Renal Circulation; Suramin; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Different receptors mediating the inhibitory action of exogenous ATP and endogenously released purines on guinea-pig intestinal peristalsis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apamin; Female; Guinea Pigs; Ileum; In Vitro Techniques; Intestines; Male; Peristalsis; Purines; Pyridoxal Phosphate; Receptors, Purinergic; Receptors, Purinergic P2; Suramin; Thionucleotides | 1999 |
Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Pressure; Carbolines; Electrophysiology; Heart Rate; Jejunum; Male; Mesentery; Neurons, Afferent; omega-Conotoxins; Peptides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Serotonin; Suramin | 1999 |
ATP released from perivascular nerves hyperpolarizes smooth muscle cells by releasing an endothelium-derived factor in hamster mesenteric arteries.
Topics: Adenosine Triphosphate; Animals; Cricetinae; Electric Stimulation; Endothelium, Vascular; Excitatory Postsynaptic Potentials; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mesocricetus; Microelectrodes; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Prazosin; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Triazines | 1999 |
Two different P2Y receptors linked to steroidogenesis in bovine adrenocortical cells.
Topics: Adenosine Triphosphate; Adrenal Cortex; Animals; Calcium; Cattle; Cells, Cultured; GTP-Binding Proteins; Inositol Phosphates; Pertussis Toxin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; Suramin; Uridine Triphosphate; Virulence Factors, Bordetella | 1999 |
Endogenous ATP released by electrical field stimulation causes contraction via P2x- and P2y-purinoceptors in the isolated tail artery of rats.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Regional Blood Flow; Suramin; Tail; Triazines; Vasoconstriction | 1999 |
Pharmacological comparison of P2X receptors on rat coeliac, mouse coeliac and mouse pelvic ganglion neurons.
Topics: Adenosine Triphosphate; Animals; Celiac Plexus; Ganglia, Sensory; Hydrogen-Ion Concentration; Hypogastric Plexus; Male; Mice; Mice, Knockout; Neurons; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Species Specificity; Suramin; Triazines; Zinc | 2000 |
Evidence that rat hepatocytes co-express functional P2Y1 and P2Y2 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; DNA, Complementary; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2000 |
Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats.
Topics: Adenosine Triphosphate; Animals; Carrageenan; Electrophysiology; Inflammation; Injections, Spinal; Male; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Peripheral Nervous System Diseases; Platelet Aggregation Inhibitors; Posterior Horn Cells; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Spinal Nerves; Suramin | 2000 |
Functional characterization of the P2X(4) receptor orthologues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Axons; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Humans; Membrane Potentials; Mice; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Recombinant Proteins; Suramin | 2000 |
ATP as a mediator of mammalian central CO2 chemoreception.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Chemoreceptor Cells; Dose-Response Relationship, Drug; Iontophoresis; Male; Medulla Oblongata; Microelectrodes; Neurons; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Suramin; Theophylline | 2000 |
Functional expression of three P2X(2) receptor splice variants from guinea pig cochlea.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cochlea; Electrophysiology; Guinea Pigs; Humans; Ion Channel Gating; Kidney; Membrane Potentials; Neuropeptides; Patch-Clamp Techniques; Plasmids; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Transfection | 2000 |
The effect of P2 receptor antagonists and ATPase inhibition on sympathetic purinergic neurotransmission in the guinea-pig isolated vas deferens.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Electrophysiology; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Motor Endplate; Muscle Contraction; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Spectrometry, Fluorescence; Suramin; Sympathetic Nervous System; Synaptic Transmission; Vas Deferens | 2000 |
P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation.
Topics: Adenosine Triphosphate; Age Factors; Animals; Antineoplastic Agents; Capsaicin; Dose-Response Relationship, Drug; Injections, Intra-Arterial; Lingual Nerve; Neurons, Afferent; Physical Stimulation; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Stimulation, Chemical; Suramin; Taste; Tongue | 2000 |
P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics.
Topics: Adenosine Triphosphate; Anesthesia; Anesthetics, Inhalation; Animals; Antineoplastic Agents; Brain; Drug Delivery Systems; Drug Interactions; Gases; Isoflurane; Male; Methyl Ethers; Pain; Platelet Aggregation Inhibitors; Pulmonary Alveoli; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Sevoflurane; Signal Transduction; Suramin; Synaptic Transmission; Wakefulness | 2000 |
Inhibitory effects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding, Competitive; Catalysis; Cell Membrane; Dinucleoside Phosphates; Enzyme Inhibitors; Hydrolysis; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Substrate Specificity; Suramin; Triazines | 2000 |
ATP P2X receptors play little role in the maintenance of neuropathic hyperalgesia.
Topics: Aggression; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Injections, Spinal; Ligation; Male; Motor Activity; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Sciatic Nerve; Spinal Cord; Suramin; Wounds and Injuries | 2000 |
The novel heteromeric bivalent ligand SB9 potently antagonizes P2Y(1) receptor-mediated responses.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Female; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Ligands; Male; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Suramin; Vas Deferens; Xenopus laevis | 2000 |
Inhibition by ethanol of rat P2X(4) receptors expressed in Xenopus oocytes.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Gene Expression Regulation; Membrane Potentials; Oocytes; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; RNA, Complementary; Suramin; Triazines; Xenopus laevis | 2000 |
Purinergic and noradrenergic cotransmission in the rat pineal gland.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male; Melatonin; Norepinephrine; Pineal Gland; Propranolol; Pyridoxal Phosphate; Rats; Rats, Wistar; Serotonin; Suramin; Synaptic Transmission; Time Factors | 2000 |
P2 purinoceptor-mediated control of rat cerebral (pial) microvasculature; contribution of P2X and P2Y receptors.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cerebral Veins; Electrophysiology; Male; Microcirculation; Patch-Clamp Techniques; Pyridoxal Phosphate; Pyrimidine Nucleotides; Rats; Rats, Wistar; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Vasoconstriction; Vasodilation | 2000 |
Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Mesenteric Artery, Inferior; Mesenteric Veins; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Chloride; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrimidine Nucleotides; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate | 2000 |
Regulation of the development of allodynia by intrathecally administered P2 purinoceptor agonists and antagonists in mice.
Topics: Adenosine Triphosphate; Animals; Dinoprostone; Dizocilpine Maleate; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Oxytocics; Pain; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin | 2000 |
Diadenosine polyphosphates facilitate the evoked release of acetylcholine from rat hippocampal nerve terminals.
Topics: Acetylcholine; Animals; Dinucleoside Phosphates; Hippocampus; Male; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P1; Suramin; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines | 2000 |
Orphanin FQ causes contractions via inhibiting purinergic pathway in the rat colon.
Topics: Animals; Apamin; Colon; In Situ Hybridization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nociceptin; Nociceptin Receptor; Opioid Peptides; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Purinergic P2; Suramin; Tetrodotoxin; Transcription, Genetic; Triazines | 2000 |
Descending inhibitory reflexes involve P2X receptor-mediated transmission from interneurons to motor neurons in guinea-pig ileum.
Topics: Animals; Efferent Pathways; Electrophysiology; Female; Gap Junctions; Guinea Pigs; Ileum; In Vitro Techniques; Interneurons; Male; Motor Neurons; Nerve Block; Neural Inhibition; Physical Stimulation; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Reflex; Suramin; Synapses; Synaptic Transmission | 2000 |
Antiproliferative effect of UTP on human arterial and venous smooth muscle cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Cell Division; Cells, Cultured; Humans; Inositol 1,4,5-Trisphosphate; Mammary Arteries; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Platelet Aggregation Inhibitors; Platelet-Derived Growth Factor; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Saphenous Vein; Suramin; Thymidine; Tritium; Type C Phospholipases; Uridine Triphosphate | 2000 |
Characterisation of ATP-induced facilitation of transmission in rat hippocampus.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Caffeine; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Synaptic Transmission; Theophylline | 2000 |
Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Electric Stimulation; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Neuromuscular Junction; Oxymetazoline; Phentolamine; Pyridoxal Phosphate; Receptors, Adrenergic, alpha-2; Reserpine; Suramin; Yohimbine | 2001 |
Lack of run-down of smooth muscle P2X receptor currents recorded with the amphotericin permeabilized patch technique, physiological and pharmacological characterization of the properties of mesenteric artery P2X receptor ion channels.
Topics: Adenosine Triphosphate; Amphotericin B; Animals; Calcium; Cell Membrane Permeability; Dose-Response Relationship, Drug; Guanosine Triphosphate; Immunohistochemistry; Ion Channels; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; Receptors, Purinergic P2X5; Receptors, Purinergic P2X7; Suramin; Thionucleotides; Time Factors | 2000 |
Multiple P2X receptors on guinea-pig pelvic ganglion neurons exhibit novel pharmacological properties.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Electrophysiology; Ganglia, Autonomic; Guinea Pigs; Hydrogen-Ion Concentration; Male; Mice; Neurons; Nodose Ganglion; Patch-Clamp Techniques; Pelvis; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Suramin; Zinc | 2001 |
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Arterioles; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y2; Suramin; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasodilation | 2001 |
Mechanism of prolonged vasorelaxation to ATP in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Animals; Capsaicin; Cardiotonic Agents; Cardiovascular Agents; Charybdotoxin; Drug Interactions; Electric Stimulation; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Mesenteric Arteries; Neurons, Afferent; Ouabain; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Tetraethylammonium; Theophylline; Vasodilation | 2001 |
Molecular cloning and characterization of the mouse P2Y4 nucleotide receptor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Cloning, Molecular; Dose-Response Relationship, Drug; Humans; Inositol 1,4,5-Trisphosphate; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Suramin; Transfection; Triazines; Tumor Cells, Cultured; Uridine Triphosphate | 2001 |
Nucleotide-evoked relaxation of rat vas deferens--a possible role for endogenous ATP released upon alpha(1)-adrenoceptor stimulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Norepinephrine; Nucleotides; Potassium; Purinergic P1 Receptor Antagonists; Pyridoxal Phosphate; Pyrophosphatases; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Suramin; Theophylline; Thionucleotides; Triazines; Vas Deferens; Vasoconstrictor Agents | 2001 |
Excitatory effect of ATP on acutely dissociated ventromedial hypothalamic neurons of the rat.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Magnesium; Membrane Potentials; Neurons; Platelet Aggregation Inhibitors; Potassium Chloride; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Sodium; Sodium Channels; Suramin; Ventromedial Hypothalamic Nucleus; Zinc | 2001 |
Extracellular nucleotides regulate cellular functions of podocytes in culture.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line, Transformed; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Extracellular Space; Ion Transport; Kidney Glomerulus; Mice; Nucleotides; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Leukotriene B4; Receptors, Purinergic P2; RNA, Messenger; Suramin | 2001 |
Regulation of transcervical permeability by two distinct P2 purinergic receptor mechanisms.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Calcium; Calcium Signaling; Cell Membrane Permeability; Cells, Cultured; Cervix Uteri; Chelating Agents; Egtazic Acid; Epithelial Cells; Female; Guanosine Triphosphate; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2Y2; Suramin; Uridine Triphosphate | 2002 |
Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Suramin; Transfection | 2002 |
TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics.
Topics: Abdomen; Acetic Acid; Adenosine Triphosphate; Analgesics; Animals; Antineoplastic Agents; Behavior, Animal; Calcium; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2X3; Suramin | 2002 |
Involvement of purinergic signalling in central mechanisms of body temperature regulation in rats.
Topics: Adenosine Triphosphate; Animals; Body Temperature Regulation; Brain; Fever; Hypothalamus; Injections, Intraventricular; Lipopolysaccharides; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Suramin | 2002 |
Modulation of phrenic motoneuron excitability by ATP: consequences for respiratory-related output in vitro.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain Stem; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neck; Neural Inhibition; Periodicity; Phrenic Nerve; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Respiration; Spinal Cord; Spinal Nerve Roots; Suramin | 2002 |
Characteristics of ATP-induced current through P2X7 receptor in NG108-15 cells: unique antagonist sensitivity and lack of pore formation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Benzoxazoles; Cations; Cell Membrane Permeability; Fluorescent Dyes; Mice; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinolinium Compounds; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Suramin; Triazines; Tumor Cells, Cultured | 2002 |
Activation of ATP receptor increases the cytosolic Ca(2+) concentration in ventral tegmental area neurons of rat brain.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cytosol; Dopamine; Glutamic Acid; Neurons; Nicotine; Organ Culture Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sodium; Suramin; Ventral Tegmental Area | 2002 |
ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Culture Techniques; Electric Stimulation; Female; Granisetron; Guinea Pigs; Intestinal Mucosa; Male; Myenteric Plexus; Neurons, Afferent; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Signal Transduction; Suramin | 2002 |
Suramin-induced reversal of chronic cerebral vasospasm in experimental subarachnoid hemorrhage.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Chronic Disease; Dogs; Female; Male; Oxyhemoglobins; Phosphorylation; Platelet Aggregation Inhibitors; Protein-Tyrosine Kinases; Pyridoxal Phosphate; Receptors, Purinergic P2; Subarachnoid Hemorrhage; Suramin; Tyrosine; Vasospasm, Intracranial | 2002 |
ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Fetus; Growth Inhibitors; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Microglia; Neurons; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; Suramin; Uridine Triphosphate | 2002 |
Sensory afferent selective role of P2 receptors in the nucleus tractus solitarii for mediating the cardiac component of the peripheral chemoreceptor reflex in rats.
Topics: Action Potentials; Animals; Antineoplastic Agents; Bradycardia; Chemoreceptor Cells; Heart; Microinjections; Neurons, Afferent; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reflex; Solitary Nucleus; Suramin; Synapses | 2002 |
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; Glycine; Humans; Immunohistochemistry; Neural Inhibition; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Spinal Cord; Suramin; Synaptic Membranes; Synaptic Transmission; Zinc | 2002 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
P2X purinergic receptor antagonist accelerates skin barrier repair and prevents epidermal hyperplasia induced by skin barrier disruption.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Calcium; Cells, Cultured; Epidermis; Fluorescent Dyes; Hyperplasia; Immunohistochemistry; Keratinocytes; Male; Mice; Mice, Hairless; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Water; Wound Healing | 2002 |
Presence of diadenosine polyphosphates in the aqueous humor: their effect on intraocular pressure.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Intraocular Pressure; Kinetics; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Structure-Activity Relationship; Suramin; Triazines | 2003 |
Cloning, tissue distribution and functional characterization of the chicken P2X1 receptor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Chick Embryo; Chickens; Cloning, Molecular; DNA, Complementary; Humans; Molecular Sequence Data; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Recombinant Proteins; Sequence Homology, Amino Acid; Suramin; Tissue Distribution | 2003 |
P2Y-receptor regulates size of endothelial cells in an intracellular Ca2+ dependent manner.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Size; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Male; Osmotic Pressure; Phosphodiesterase Inhibitors; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thapsigargin; Thionucleotides | 2003 |
ATP-induced calcium oscillations and change of P2Y subtypes with culture conditions in HeLa cells.
Topics: Adenosine Triphosphate; Calcium; Calcium Signaling; Cell Culture Techniques; HeLa Cells; Humans; Protein Isoforms; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Uridine Diphosphate | 2003 |
ATP-induced, sustained calcium signalling in cultured rat cortical astrocytes: evidence for a non-capacitative, P2X7-like-mediated calcium entry.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Suramin | 2003 |
ATP released from astrocytes during swelling activates chloride channels.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apyrase; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chloride Channels; Chlorides; Hypotonic Solutions; Membrane Potentials; Platelet Aggregation Inhibitors; Probenecid; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Uricosuric Agents; Water-Electrolyte Balance | 2003 |
P2Y receptor specific for diadenosine tetraphosphate in lung: selective inhibition by suramin, PPADS, Ip5I, and not by MRS-2197.
Topics: Adenosine Diphosphate; Animals; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Dinucleoside Phosphates; Epithelial Cells; Humans; Lung; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Suramin | 2003 |
Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors.
Topics: Adenosine Triphosphate; Animals; Apyrase; Astrocytes; Astrocytoma; Calcium; Calcium Signaling; Cells, Cultured; Enzyme Inhibitors; Humans; Physical Stimulation; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Suramin; Transfection; Uridine Triphosphate | 2003 |
Early glial cell reactivity in experimental retinal detachment: effect of suramin.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Female; Hyaluronic Acid; Male; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Potassium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rabbits; Receptors, Purinergic P2; Retinal Detachment; Suramin; Up-Regulation | 2003 |
ATP modulates intracellular Ca2+ and firing rate through a P2Y1 purinoceptor in cane toad pacemaker cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Clocks; Blotting, Western; Bufo marinus; Calcium; Electrophysiology; Heart; Immunohistochemistry; Intracellular Membranes; Myocardium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Sarcoplasmic Reticulum; Suramin; Thionucleotides; Type C Phospholipases | 2003 |
P2Y(2) receptor elicits PAS-positive glycoprotein secretion from rabbit conjunctival goblet cells in vivo.
Topics: Adenosine Triphosphate; Animals; Conjunctiva; Glycoproteins; Goblet Cells; Male; Mucins; Periodic Acid-Schiff Reaction; Photomicrography; Pyridoxal Phosphate; Rabbits; Receptors, Purinergic P2; Suramin; Time Factors; Uridine Triphosphate | 2003 |
Discrete but simultaneous release of adenine nucleotides and serotonin from mouse megakaryocytes as detected with patch- and carbon-fiber electrodes.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Carbon; Carbon Fiber; Electrodes; Electrophysiology; Megakaryocytes; Mice; Mice, Inbred BALB C; Patch-Clamp Techniques; Platelet Activation; Pyridoxal Phosphate; Serotonin; Suramin; Time Factors | 2004 |
Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved.
Topics: Adenosine Triphosphate; Animals; Apamin; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Jejunum; Mice; Muscle Relaxation; Muscle, Smooth; Neurotransmitter Agents; Nitric Oxide Synthase; Nitroarginine; Protein Isoforms; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Synaptic Transmission; Thionucleotides | 2003 |
P2X receptor-mediated excitatory synaptic currents in somatosensory cortex.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Nicotinic Antagonists; Organ Culture Techniques; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Serotonin Antagonists; Somatosensory Cortex; Suramin; Synapses; Synaptic Transmission | 2003 |
Synthesis of nitric oxide in postganglionic myenteric neurons during endotoxemia: implications for gastric motor function in rats.
Topics: Animals; Apamin; Autonomic Fibers, Postganglionic; Carbachol; Dexamethasone; Endotoxemia; Gastric Fundus; Gastrointestinal Motility; Guanylate Cyclase; Microscopy, Confocal; Nerve Tissue Proteins; Nicotine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Nitroso Compounds; Peptide Fragments; Potassium Channels, Calcium-Activated; Pyrazoles; Pyridines; Pyridoxal Phosphate; Rats; Suramin; Tetrodotoxin; Vasoactive Intestinal Peptide | 2004 |
[3H]alpha,beta-methylene ATP binding to P2X purinoceptor is unaffected by volatile anaesthetics.
Topics: Adenosine Triphosphate; Analysis of Variance; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Isoflurane; Male; Methyl Ethers; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Sevoflurane; Suramin; Synaptic Membranes; Synaptic Transmission; Tritium | 2004 |
Cardiovascular responses to microinjection of ATP into the nucleus tractus solitarii of awake rats.
Topics: Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Atropine Derivatives; Autonomic Nervous System; Blood Pressure; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heart Rate; Hemodynamics; Kynurenic Acid; Male; Microinjections; Prazosin; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Solitary Nucleus; Suramin; Xanthines | 2004 |
Role of extracellular histidines in antagonist sensitivity of the rat P2X4 receptor.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Histidine; Humans; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Suramin; Transfection; Xenopus | 2004 |
Divergent effects of the purinoceptor antagonists suramin and pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) (PPNDS) on alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Topics: Animals; Brain; Cell Line; Cell Membrane; Humans; Kidney; Membrane Potentials; Patch-Clamp Techniques; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, AMPA; Sulfonic Acids; Suramin | 2004 |
Cooperation in signal transduction of extracellular guanosine 5' triphosphate and nerve growth factor in neuronal differentiation of PC12 cells.
Topics: Animals; Barbiturates; Blotting, Western; Calcium; Calcium Channel Blockers; Cell Count; Cell Differentiation; Chelating Agents; Clotrimazole; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fluorescent Antibody Technique; Fluorescent Dyes; Gallic Acid; Growth Inhibitors; Guanosine Triphosphate; Ionomycin; Ionophores; Isoxazoles; Membrane Potentials; Microscopy, Confocal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nerve Growth Factor; Neurites; Nifedipine; PC12 Cells; Pertussis Toxin; Pyridoxal Phosphate; Rats; Signal Transduction; Suramin; Time Factors; Triazines | 2004 |
Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia.
Topics: Animals; Calcium; Cells, Cultured; Female; Fluorescent Dyes; Male; Mice; Mice, Inbred C57BL; Neuroglia; Neurons; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Superior Cervical Ganglion; Suramin; Uridine Diphosphate; Uridine Triphosphate | 2004 |
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Monophosphate; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Sympathetic; Membrane Potentials; Membrane Proteins; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Phenethylamines; Potassium; Purine Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Thionucleosides; Tritium | 2004 |
Varicosity-Schwann cell interactions mediated by ATP in the mouse vas deferens.
Topics: Adenosine Triphosphate; Adrenergic Fibers; Aniline Compounds; Animals; Caffeine; Calcium; Cell Count; Drug Interactions; Electric Stimulation; Estrenes; Evoked Potentials; Fluorescent Dyes; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Organic Chemicals; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Pyrrolidinones; Quinazolines; S100 Proteins; Schwann Cells; Suramin; Time Factors; Triazoles; Uridine Triphosphate; Vas Deferens; Xanthenes | 2005 |
Secretion of ATP from Schwann cells in response to uridine triphosphate.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Botulinum Toxins; Botulinum Toxins, Type A; Brefeldin A; Calcium; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Estrenes; Furosemide; Glyburide; Glycyrrhetinic Acid; Guanosine Triphosphate; Immunohistochemistry; Isoquinolines; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Synthesis Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Schwann Cells; Sciatic Nerve; Sulfonamides; Suramin; Thapsigargin; Time Factors; Type C Phospholipases; Uridine Triphosphate | 2005 |
Induction of apoptosis in bone marrow cells is mediated via purinergic receptors.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Bone Marrow Cells; Doxorubicin; Male; Mice; Necrosis; Pyridoxal Phosphate; Receptors, Purinergic; Suramin | 2004 |
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Potassium Chloride; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Temperature; Theophylline | 2005 |
Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress.
Topics: Adenosine Triphosphate; Animals; Blotting, Western; Calcium; Calcium Signaling; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Enzyme Activation; Immunohistochemistry; L-Lactate Dehydrogenase; Myocytes, Cardiac; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Stress, Physiological; Suramin; Time Factors; Triazines; Type C Phospholipases; Uracil Nucleotides; Uridine; Uridine Diphosphate; Uridine Triphosphate | 2005 |
Direct excitation of hypocretin/orexin cells by extracellular ATP at P2X receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Analysis of Variance; Animals; Bicuculline; Choline; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; GABA Antagonists; Green Fluorescent Proteins; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexin Receptors; Orexins; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Suramin; Tetrodotoxin | 2005 |
P2 receptor blockade attenuates fever and cytokine responses induced by lipopolysaccharide in rats.
Topics: Animals; Body Temperature; Fever; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2X7; Rosaniline Dyes; Suramin; Tumor Necrosis Factor-alpha | 2005 |
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Astrocytoma; Calcium; Cell Line; Cell Line, Tumor; Glutamic Acid; Hippocampus; Kidney; Male; Potassium; Pyramidal Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Recombinant Fusion Proteins; RNA, Messenger; Subcellular Fractions; Suramin; Synaptosomes; Transfection; Triazines; Triazoles; Xanthines | 2005 |
Neurally released ATP mediates endothelium-dependent hyperpolarization in the circular smooth muscle cells of chicken anterior mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Chickens; Electric Stimulation; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins I; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 2005 |
P2X receptors in mouse Leydig cells.
Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Leydig Cells; Male; Mice; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin | 2006 |
The effect of P2X receptor activity on GABAA receptor-mediated inhibition in the gerbil hippocampus.
Topics: Adenosine Triphosphate; Animals; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Agonists; Gerbillinae; Hippocampus; In Vitro Techniques; Muscimol; Pyridoxal Phosphate; Receptors, GABA-A; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Synaptic Transmission | 2005 |
ATPgammaS enhances the production of inflammatory mediators by a human dermal endothelial cell line via purinergic receptor signaling.
Topics: Adenosine Triphosphate; Apoptosis; Cell Line; Chemokine CCL2; Chemokine CXCL1; Chemokines, CXC; Endothelial Cells; Humans; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Interleukin-6; Interleukin-8; Pyridoxal Phosphate; Receptors, Purinergic; Receptors, Purinergic P2; Receptors, Purinergic P2X; Signal Transduction; Skin; Suramin | 2006 |
Activation of P2Y receptor enhances high-molecular compound absorption from rat ileum.
Topics: Adenosine Triphosphate; Animals; Dextrans; Fluorescein-5-isothiocyanate; Ileum; Intestinal Absorption; Male; Nucleotides; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thionucleotides | 2006 |
Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats.
Topics: Adrenergic Fibers; Animals; Body Temperature; Body Temperature Regulation; Cold Temperature; Foot; Male; Microcirculation; Presynaptic Terminals; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Purinergic P2; Regional Blood Flow; Skin; Skin Temperature; Suramin | 2006 |
Activation of Src/kinase/phospholipase C/mitogen-activated protein kinase and induction of neurite expression by ATP, independent of nerve growth factor.
Topics: Adenosine; Adenosine Triphosphate; Animals; Butadienes; Cell Line, Tumor; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Mice; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Neurites; Neuroblastoma; Nitriles; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; src-Family Kinases; Suramin; Type C Phospholipases | 2006 |
Hypotonic stress activates BK channels in clonal kidney cells via purinergic receptors, presumably of the P2Y subtype.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Calcium; Cell Size; Chlorocebus aethiops; Fluorometry; Fura-2; Humans; Hypotonic Solutions; Kidney; Molecular Sequence Data; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology; Suramin; Vero Cells | 2006 |
The co-treatments of vigabatrin and P2X receptor antagonists protect ischemic neuronal cell death in the gerbil hippocampus.
Topics: Adenosine Triphosphatases; Animals; Cell Death; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Gerbillinae; Hippocampus; Immunohistochemistry; Ischemia; Male; Neurons; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Time Factors; Vigabatrin | 2006 |
Purinergic control of the quail rectum: modulation of adenosine 5'-triphosphate-mediated contraction with acetylcholine.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Cholinesterase Inhibitors; Coturnix; Electric Stimulation; Female; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Physostigmine; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Rectum; Suramin | 2007 |
Uracil nucleotides stimulate human neural precursor cell proliferation and dopaminergic differentiation: involvement of MEK/ERK signalling.
Topics: Adenine Nucleotides; Blotting, Western; Cell Count; Cell Death; Cell Differentiation; Cell Proliferation; Dopamine; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Humans; Mesencephalon; Nerve Tissue Proteins; Neurons; Oligonucleotide Array Sequence Analysis; Patch-Clamp Techniques; Pyridoxal Phosphate; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stem Cells; Suramin; Uracil Nucleotides; Uridine Triphosphate | 2006 |
Purinergic nerves mediate the non-nitrergic relaxation of the human ileum in response to electrical field stimulation.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Electric Stimulation; Enteric Nervous System; Enzyme Inhibitors; Humans; Ileum; Isoproterenol; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Purinergic P2 Receptor Antagonists; Purines; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 2006 |
Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladder.
Topics: Animals; Atropine; Drug Resistance; Guinea Pigs; Male; Muscle Contraction; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Urinary Bladder; Urinary Bladder, Neurogenic; Vas Deferens | 2007 |
Evidence for the expression of multiple uracil nucleotide-stimulated P2 receptors coupled to smooth muscle contraction in porcine isolated arteries.
Topics: Animals; Blotting, Western; Coronary Vessels; Dose-Response Relationship, Drug; Ear; Gene Expression; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Suramin; Swine; Uracil Nucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction | 2007 |
Activation-dependent trafficking of NTPDase2 in Chinese hamster ovary cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Green Fluorescent Proteins; Hydrolysis; Intracellular Fluid; Microscopy, Confocal; Protein Transport; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Recombinant Fusion Proteins; Suramin; Time Factors; Transfection; Uridine Diphosphate; Uridine Triphosphate | 2007 |
Quantal release of ATP in mouse cortex.
Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Glutamate; Suramin | 2007 |
P19 embryonal carcinoma cells as in vitro model for studying purinergic receptor expression and modulation of N-methyl-D-aspartate-glutamate and acetylcholine receptors during neuronal differentiation.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Line; Embryonal Carcinoma Stem Cells; Fluorescent Antibody Technique; Immunohistochemistry; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Neoplastic Stem Cells; Neurons; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Purinergic; Receptors, Purinergic P1; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin; Triazines | 2007 |
Vesicular ATP is the predominant cause of intercellular calcium waves in astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aniline Compounds; Animals; Apyrase; Astrocytes; Brefeldin A; Calcium; Calcium Signaling; Cells, Cultured; Cytoplasmic Vesicles; Diffusion; Enzyme Inhibitors; Fluorescent Dyes; Hippocampus; Macrolides; Neurons; Paracrine Communication; Proton-Translocating ATPases; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Suramin; Time Factors; Xanthenes | 2007 |
P2 purinoceptor antagonists inhibit the non-adrenergic, non-cholinergic relaxation of the human colon in vitro.
Topics: Adenosine Triphosphate; Colon, Sigmoid; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Neurotransmitter Agents; Nitrergic Neurons; Nitric Acid; Nitric Oxide; Nitroarginine; Oxadiazoles; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinoxalines; Receptors, Purinergic P2; Statistics, Nonparametric; Suramin | 2007 |
Downregulation of SGK1 by nucleotides in renal tubular epithelial cells.
Topics: Adenosine Triphosphate; Aldosterone; Animals; Cell Line; Cytosol; Down-Regulation; Epithelial Cells; Immediate-Early Proteins; Kidney Medulla; Kidney Tubules, Collecting; Mice; Nucleotides; Protein Serine-Threonine Kinases; Purinergic Antagonists; Pyridoxal Phosphate; Sulfonic Acids; Suramin | 2007 |
Ca2+-dependent ATP release from A549 cells involves synergistic autocrine stimulation by coreleased uridine nucleotides.
Topics: Adenosine Triphosphate; Apyrase; Autocrine Communication; Caffeine; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Cell Line, Tumor; Endoplasmic Reticulum; Enzyme Inhibitors; Epithelial Cells; Humans; Hydrolysis; Hypotonic Solutions; Inositol 1,4,5-Trisphosphate Receptors; Lung Neoplasms; Osmotic Pressure; Paracrine Communication; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Thapsigargin; Time Factors; Uracil Nucleotides | 2007 |
A positive inotropic effect of ATP in the human cardiac atrium.
Topics: Adenosine A1 Receptor Antagonists; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Aged; Aged, 80 and over; Cardiotonic Agents; Coronary Artery Bypass; Coronary Disease; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Estrenes; Heart Atria; Humans; Middle Aged; Myocardial Contraction; Myocardium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Receptor, Adenosine A1; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Severity of Illness Index; Signal Transduction; Suramin; Thionucleotides; Triazines; Type C Phospholipases; Xanthines | 2008 |
Involvement of purinergic P2 receptors in experimental retinal neovascularization.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Oxygen; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2Y2; Retina; Retinal Neovascularization; Suramin | 2008 |
Endogenous ATP potentiates only vasopressin secretion from neurohypophysial terminals.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Antineoplastic Agents; Arginine Vasopressin; Male; Nerve Endings; Oxytocin; Patch-Clamp Techniques; Pituitary Gland, Posterior; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Suramin; Vasopressins | 2008 |
ATP activates P2x receptors and requires extracellular Ca(++) participation to modify outer hair cell nonlinear capacitance.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Calcium; Chelating Agents; Egtazic Acid; Electric Capacitance; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Patch-Clamp Techniques; Potassium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Signal Transduction; Sodium; Suramin; Time Factors; Uridine Triphosphate | 2008 |
High-frequency fatigue of skeletal muscle: role of extracellular Ca(2+).
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cell Membrane; Elapid Venoms; Electric Stimulation; Extracellular Fluid; Gadolinium; In Vitro Techniques; Ionophores; Mice; Muscle Contraction; Muscle Fatigue; Muscle Strength; Muscle, Skeletal; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Sodium-Calcium Exchanger; Suramin; Thiourea; Time Factors; Triazines | 2008 |
Volume-activated chloride channels in mice Leydig cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adenosine Triphosphate; Animals; Cell Membrane Permeability; Cell Size; Chloride Channels; Chlorides; Cyclic AMP; In Vitro Techniques; Ion Channel Gating; Kinetics; Leydig Cells; Male; Membrane Potentials; Mice; Nitrobenzoates; Osmotic Pressure; Protein Kinase Inhibitors; Protein Kinases; Pyridoxal Phosphate; Staurosporine; Suramin | 2008 |
Purinergic type 2 receptors at GABAergic synapses on ventral tegmental area dopamine neurons are targets for ethanol action.
Topics: Adenosine Triphosphate; Animals; Ethanol; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Sodium Channels; Suramin; Synapses; Tetrodotoxin; Ventral Tegmental Area | 2008 |
Alteration of cholinergic, purinergic and sensory neurotransmission in the mouse colon of food allergy model.
Topics: Acetylcholine; Animals; Atropine; Capsaicin; Chemokine CCL2; Colon; Disease Models, Animal; Electric Stimulation; Food Hypersensitivity; Gastrointestinal Motility; Hexamethonium; Male; Mast Cells; Mice; Mice, Inbred BALB C; Nicotinic Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Synaptic Transmission | 2008 |
Dual effect of ATP on glucose-induced insulin secretion in HIT-T15 cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Feedback, Physiological; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Kinase C; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Suramin; Tetradecanoylphorbol Acetate; Thionucleotides | 2008 |
P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal bicarbonate secretion.
Topics: Adenosine Diphosphate; Aminoquinolines; Animals; Bicarbonates; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cell Line; Dogs; Duodenum; Epithelial Cells; Estrenes; Female; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestinal Secretions; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Pyrrolidinones; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Suramin; Time Factors; Uridine Triphosphate | 2009 |
Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Collodion; Immunoassay; Immunohistochemistry; In Vitro Techniques; Mice; Neuropeptide Y; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Uridine Triphosphate | 2009 |
Modulation of firing activity by ATP in dopamine neurons of the rat substantia nigra pars compacta.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Calcium; Central Nervous System Agents; Cytoplasm; Dopamine; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substantia Nigra; Suramin; Thionucleotides | 2009 |
P2X antagonists inhibit styryl dye entry into hair cells.
Topics: Adenosine Triphosphate; Animals; Chelating Agents; Chickens; Connexins; Egtazic Acid; Epithelium; Fluorescence; Fluorescent Dyes; Hair Cells, Auditory; In Vitro Techniques; Mechanotransduction, Cellular; Purinergic P2 Receptor Antagonists; Pyridinium Compounds; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Receptors, Purinergic P2; Suramin; Tubocurarine | 2009 |
Regulation of adenosine 5'-triphosphate (ATP)-gated P2X(4) receptors on tracheal smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression Regulation; Imidazoles; Ivermectin; Membrane Potentials; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X4; RNA, Messenger; Suramin; Swine; Trachea; Verapamil | 2009 |
Activation of purinergic receptors by ATP induces ventricular tachycardia by membrane depolarization and modifications of Ca2+ homeostasis.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium; In Vitro Techniques; Membrane Potentials; Mice; Microscopy, Confocal; Myocytes, Cardiac; Patch-Clamp Techniques; Purinergic Agonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Tachycardia, Ventricular | 2009 |
Two suramin binding sites are present in guinea pig but only one in murine native P2X myenteric receptors.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Biomechanical Phenomena; Electric Conductivity; Female; Guinea Pigs; Male; Mice; Myenteric Plexus; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin | 2010 |
Functional characterization of intracellular Dictyostelium discoideum P2X receptors.
Topics: Animals; Calcium; Calcium Signaling; Copper; Dictyostelium; Oocytes; Patch-Clamp Techniques; Protein Isoforms; Purines; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Recombinant Fusion Proteins; Suramin; Water-Electrolyte Balance; Xenopus laevis | 2009 |
P2Y receptors and atherosclerosis in apolipoprotein E-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Line; Interleukin-6; Macrophages; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; RNA, Messenger; Suramin; Uridine Diphosphate | 2010 |
Nickel sulfate induces location-dependent atrophy of mouse olfactory epithelium: protective and proliferative role of purinergic receptor activation.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Atrophy; Cell Proliferation; Cell Survival; Drug Therapy, Combination; Male; Mice; Nickel; Olfactory Bulb; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Turbinates | 2010 |
Spontaneous Ca2+ oscillations via purinergic receptors elicit transient cell swelling in rat parotid ducts.
Topics: Adenosine Triphosphate; Animals; Calcium; Electrolytes; Hypertrophy; Parotid Gland; Purinergic Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic; Suramin | 2009 |
Blocking P2X receptors can inhibit the injury-induced proliferation of olfactory epithelium progenitor cells in adult mouse.
Topics: Animals; Apoptosis; Caspase 3; Cell Proliferation; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Olfactory Bulb; Olfactory Mucosa; Olfactory Receptor Neurons; Polymerase Chain Reaction; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2X; RNA, Messenger; Stem Cells; Suramin | 2010 |
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Suramin; Theophylline; Uracil Nucleotides; Urinary Bladder; Xanthines | 2010 |
Intracellular Ca2+ responses and cell volume regulation upon cholinergic and purinergic stimulation in an immortalized salivary cell line.
Topics: Adenosine Triphosphate; Animals; Aquaporin 5; Atropine; Calcium Signaling; Carbachol; Cell Culture Techniques; Cell Line, Transformed; Cell Size; Cholinergic Agents; Cholinergic Agonists; Fluorescent Dyes; Fura-2; Muscarinic Antagonists; Osmotic Pressure; Purinergic P2 Receptor Antagonists; Purines; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2X; Ruthenium Red; Submandibular Gland; Suramin; TRPV Cation Channels | 2010 |
Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Proliferation; Green Fluorescent Proteins; Intermediate Filament Proteins; Lumbar Vertebrae; Mice; Mice, Transgenic; Nerve Tissue Proteins; Nestin; Neuroglia; Pyridoxal Phosphate; Spinal Cord; Spinal Cord Injuries; Spinal Nerves; Stem Cells; Suramin | 2010 |
Differential effects of uridine adenosine tetraphosphate on purinoceptors in the rat isolated perfused kidney.
Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Kidney; Male; Nitric Oxide Synthase; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Inbred WKY; Receptors, Purinergic; Suramin; Triazines; Vasoconstriction; Vasodilation | 2010 |
Astrocytes in the retrotrapezoid nucleus sense H+ by inhibition of a Kir4.1-Kir5.1-like current and may contribute to chemoreception by a purinergic mechanism.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Barium; Carbon Dioxide; Chemoreceptor Cells; Citrates; Desipramine; Hydrogen-Ion Concentration; Kir5.1 Channel; Neurons; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Respiratory Center; Sodium-Bicarbonate Symporters; Suramin | 2010 |
Propionate-induced epithelial K(+) and Cl(-)/HCO3(-) secretion and free fatty acid receptor 2 (FFA2, GPR43) expression in the guinea pig distal colon.
Topics: Animals; Atropine; Bicarbonates; Bumetanide; Capsaicin; Chlorides; Colon; Dioxanes; Enteroendocrine Cells; Fatty Acids, Nonesterified; Granisetron; Guinea Pigs; Hexamethonium; Intestinal Mucosa; Male; omega-Conotoxin GVIA; Piperidines; Potassium; Propionates; Pyridoxal Phosphate; Receptors, G-Protein-Coupled; Serous Membrane; Suramin; Tetrodotoxin | 2011 |
In airways ATP refills sarcoplasmic reticulum via P2X smooth muscle receptors and induces contraction through P2Y epithelial receptors.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Patch-Clamp Techniques; Prostaglandins; Pyridoxal Phosphate; Receptors, Purinergic P2X; Receptors, Purinergic P2Y; Sarcoplasmic Reticulum; Suramin; Trachea; Triazines | 2011 |
Purinergic mechanisms of lateral parabrachial nucleus facilitate sodium depletion-induced NaCl intake.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Administration Routes; Food Deprivation; Male; Pons; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2X; Sodium Chloride; Sodium Chloride, Dietary; Sucrose; Suramin; Time Factors; Water Deprivation | 2011 |
Maintained tubuloglomerular feedback responses during acute inhibition of P2 purinergic receptors in mice.
Topics: Adenosine Triphosphate; Animals; Arterioles; Blood Pressure; Feedback, Physiological; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Male; Mice; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin; Vasoconstriction | 2011 |
Purinergic modulation of glucose uptake into cultured rat podocytes: effect of diabetic milieu.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus; Female; Glucose; Podocytes; Purinergic P2 Receptor Agonists; Purinergic P2Y Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Suramin; Thionucleotides; Triazines | 2011 |
Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.
Topics: Animals; Cell Line; Hepatitis B virus; Hepatitis Delta Virus; Hepatocytes; Humans; Inflammation; Pyridoxal Phosphate; Rats; Receptors, Purinergic; Receptors, Purinergic P2X7; RNA, Viral; Rosaniline Dyes; Suramin | 2010 |
Role for purinergic receptors in memory processing in young chicks.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Chickens; Color; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Functional Laterality; Injections; Memory; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Suramin | 2011 |
Blockade of P2 nucleotide receptors after spinal cord injury reduced the gliotic response and spared tissue.
Topics: Animals; Antineoplastic Agents; Astrocytes; Behavior, Animal; Female; Glial Fibrillary Acidic Protein; Gliosis; Motor Activity; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Recovery of Function; RNA, Messenger; Spinal Cord; Spinal Cord Injuries; Suramin | 2012 |
Age-related changes in afferent responses in sensory neurons to mechanical stimulation of osteoblasts in coculture system.
Topics: Adenosine Triphosphate; Age Factors; Aniline Compounds; Animals; Animals, Newborn; Apyrase; Calcium; Calcium Channels; Coculture Techniques; Gadolinium; Ganglia, Spinal; Mechanotransduction, Cellular; Mice; Mice, Inbred BALB C; Neurites; Osteoblasts; Osteogenesis; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Satellite Cells, Perineuronal; Sensory Receptor Cells; Suramin; Xanthenes | 2012 |
P2X purinergic receptor knockout mice reveal endogenous ATP modulation of both vasopressin and oxytocin release from the intact neurohypophysis.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arginine Vasopressin; Electric Stimulation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Oxytocin; Pituitary Gland, Posterior; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Suramin | 2012 |
Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Pressure; Brain Stem; Calcium; Carbenoxolone; Carbon Dioxide; Chemoreceptor Cells; Cobalt; Connexins; Denervation; Disease Models, Animal; Gap Junctions; Hydrogen-Ion Concentration; Hypercapnia; Male; Patch-Clamp Techniques; Phrenic Nerve; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic; Receptors, Purinergic P2Y1; Respiratory Center; Respiratory Mechanics; Signal Transduction; Suramin; Temperature; Time Factors | 2012 |
Extracellular ATP signaling in equine digital blood vessels.
Topics: Adenosine Triphosphate; Animals; Arteries; Electric Stimulation; Female; Horses; In Vitro Techniques; Male; Methoxamine; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X; Suramin; Uridine Triphosphate; Vasoconstriction; Vasoconstrictor Agents; Veins | 2013 |
P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH.
Topics: Adenosine Triphosphate; Animals; Antinematodal Agents; Biological Transport, Active; Chlorocebus aethiops; COS Cells; Glutamates; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Lysosomes; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2X4; Suramin | 2014 |
Purinergic signaling via P2Y receptors up-mediates IL-6 production by liver macrophages/Kupffer cells.
Topics: Adenosine Triphosphatases; Animals; Azo Compounds; Cells, Cultured; Drug Discovery; Hepatitis; Inflammation Mediators; Interleukin-6; Kupffer Cells; Lipopolysaccharides; Liver; Macrophages; Mice, Inbred C57BL; Molecular Targeted Therapy; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2Y; Signal Transduction; Suramin; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
α,β-meATP mimics the effects of the purinergic neurotransmitter in the human and rat colon.
Topics: Adenosine Triphosphate; Aged; Animals; Apamin; Colon; Deoxyadenine Nucleotides; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats, Sprague-Dawley; Receptors, Purinergic P2Y1; Suramin | 2014 |
Diadenosine tetra- and pentaphosphates affect contractility and bioelectrical activity in the rat heart via P2 purinergic receptors.
Topics: Action Potentials; Animals; Dinucleoside Phosphates; Heart; In Vitro Techniques; Male; Myocardial Contraction; Pulmonary Veins; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats, Wistar; Receptors, Purinergic P2; Suramin | 2016 |
Viability of SH-SY5Y cells is associated with purinergic P2 receptor expression alterations.
Topics: Age Factors; Animals; Brain; Cell Line, Tumor; Cell Survival; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Male; Mice, Inbred C57BL; Protein Isoforms; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Reverse Transcriptase Polymerase Chain Reaction; Suramin | 2017 |
P2 purinergic receptor antagonists disrupt maternal behavior in lactating rats.
Topics: Animals; Behavior, Animal; Female; Lactation; Prosencephalon; Proto-Oncogene Proteins c-fos; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin | 2017 |
Activation of retinal glial (Müller) cells by extracellular ATP induces pronounced increases in extracellular H+ flux.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Diphosphate; Adenosine Triphosphate; Ambystoma; Animals; Ependymoglial Cells; Extracellular Fluid; Humans; Hydrogen-Ion Concentration; Ictaluridae; In Vitro Techniques; Ion Transport; Lampreys; Macaca fascicularis; Macaca mulatta; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2Y; Retina; Signal Transduction; Skates, Fish; Suramin | 2018 |
Contribution of ATP-Mediated Positive Feedback to Sympathetic Nerve-Induced Positive Inotropy in Guinea Pig Ventricular Myocardium.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Feedback, Physiological; Guinea Pigs; Heart Ventricles; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Prazosin; Propranolol; Pyridoxal Phosphate; Suramin; Sympathetic Nervous System; Ventricular Function | 2021 |