pyridoxal phosphate has been researched along with kynurenine in 78 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 51 (65.38) | 18.7374 |
| 1990's | 2 (2.56) | 18.2507 |
| 2000's | 5 (6.41) | 29.6817 |
| 2010's | 19 (24.36) | 24.3611 |
| 2020's | 1 (1.28) | 2.80 |
| Authors | Studies |
|---|---|
| Allegri, G; Costa, C; de Antoni, A | 2 |
| Guseĭnova, RS | 1 |
| Brown, RR; Wolf, H | 1 |
| Kilgallon, B; Shepherd, DM | 1 |
| Abdel-Tawab, GA; Ebied, SM; El-Sewedy, SM; El-Zoghby, SM; Mostafa, MH; Saad, AA | 1 |
| Barlow, GB; Wilkinson, AW | 1 |
| Brown, RR; Leklem, JE; Linkswiler, HM; Rose, DP | 1 |
| Abdel-Tawab, GA; El-Zoghby, SM; Saad, AA | 1 |
| Moriguchi, M; Soda, K; Tanizawa, K | 1 |
| Jurika, E; Rudzite, V | 1 |
| Fujimoto, H; Haneda, M; Nakatsuka, M; Nisimoto, Y; Nomura, S; Ohta, T; Shibata, Y; Takeuchi, F; Tamai, T; Tsubouchi, R | 1 |
| Lapin, IP; Ryzhov, IV | 1 |
| Jirgensone, S; Jirgensons, J; Jurika, E; Rudzite, V; Sileniece, G; Zirne, R | 1 |
| Stevens, JL | 1 |
| Curzon, G; Green, AR | 1 |
| Abdel-Daim, MH; Abdel-Tawab, GA; Amer, MS | 3 |
| Manning, B; Mason, M | 1 |
| Cole, KW; Gaertner, FH; Welch, GR | 1 |
| Ford, J; Mason, M; Wu, HL | 1 |
| Berg, CP; Loh, HH | 1 |
| Makino, K; Murakami, K; Murakami, Y | 1 |
| Abdel-Tawab, GA; el-Zoghby, SM; Mostafa, MH; Moursi, GE; Saad, AA | 1 |
| Machill, G | 1 |
| Casciano, DA; Gaertner, FH; McDermott, CE | 1 |
| Moriguchi, M; Soda, K; Yamamoto, T | 3 |
| Moriguchi, M; Soda, K | 1 |
| Abe, M; Kotake, Y; Murakami, E | 1 |
| Abdel-Daim, MH; Abdel-Tawab, GA; el-Sawy, MF; el-Sewedy, SM | 1 |
| Knapp, A; Machill, G; Teichmann, W | 1 |
| Bruckner, FE; Chamberlain, MA; Lakatos, C; Smith, HG | 1 |
| Chabner, BA; DeVita, VT; Livingston, DM; Oliverio, VT | 2 |
| Miliani, M; Petris, A; Pinamonti, S | 1 |
| Abdel-Tawab, GA; el-Shafei, AK; el-Zoghby, SM; Kelada, FS | 1 |
| Anke, A; Schmidt, E; Wolfram, G | 1 |
| Brown, RR; Madsen, PO; Wolf, H | 1 |
| Dietrich, LS; Smith, MA | 1 |
| Brown, RR; Rose, DP | 1 |
| Heeley, AF; Roberts, GE | 1 |
| Linkswiler, H | 1 |
| Abdel-Daim, MH; Abdel-Tawab, GA; Samir Amer, M | 1 |
| Ueda, T | 1 |
| Davis, RE; Wilson, RG | 1 |
| Arend, RA; Brown, RR; Walter, S; Wolf, H | 1 |
| Rumsby, PC; Shepherd, DM | 1 |
| Avanzi, N; Breton, J; Covini, N; Cozzi, L; Isacchi, A; Magagnin, S; Magistrelli, G | 1 |
| HAGINO, Y; KOTAKE, Y; OGASAWARA, N | 1 |
| CREPALDI, G; PARPAJOLA, A | 1 |
| MASON, M; WU, HL | 1 |
| Erglis, A; Fuchs, D; Jegere, S; Jurika, E; Kalnins, U; Rudzite, V; Silava, A; Trusinskis, K | 1 |
| Gao, YG; Han, Q; Li, J; Rizzi, M; Robinson, H; Vogelaar, N; Wilson, SR | 1 |
| Cai, T; Han, Q; Li, J; Robinson, H; Tagle, DA | 1 |
| Bellocchi, D; Carotti, A; Macchiarulo, A; Pellicciari, R | 1 |
| Bleie, O; Ebbing, M; Midttun, O; Nilsen, RM; Nygård, O; Ringdal Pedersen, E; Schartum-Hansen, H; Ueland, PM; Ulvik, A | 1 |
| Angkawidjaja, C; Kanaya, S; Koga, Y; Okada, K; Takano, K | 1 |
| Chi, YY; Coats, B; da Silva, VR; Garrett, TJ; Gregory, JF; Lamers, Y; Midttun, Ø; Muller, KE; Percival, SS; Quinlivan, EP; Ralat, MA; Rios-Avila, L; Shankar, MN; Stacpoole, PW; Ueland, PM | 1 |
| Ciorba, MA | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Theofylaktopoulou, D; Ueland, PM; Ulvik, A | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A | 1 |
| Eussen, SJ; Hustad, S; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Eussen, SJ; Meyer, K; Midttun, Ø; Nygård, O; Tell, GS; Ueland, PM; Ulvik, A; Vollset, SE; Zuo, H | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Gregory, JF; Midttun, Ø; Rios-Avila, L; Ueland, PM; Ulvik, A | 1 |
| Oxenkrug, GF | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B | 1 |
| Church, WB; Jayawickrama, GS; Nematollahi, A; Sun, G | 1 |
| Butler, LM; Gao, YT; Huang, JY; Jin, A; Koh, WP; Midttun, Ø; Ueland, PM; Ulvik, A; Wang, R; Yuan, JM | 1 |
| Apalset, EM; Gjesdal, CG; Hammer, HB; Midttun, Ø; Sande, JS; Ueland, PM; Ulvik, A; Valen, M | 1 |
| Fujigaki, H; Fujigaki, S; Kato, K; Kunisawa, K; Mouri, A; Nabeshima, T; Oda, A; Saito, K; Yamamoto, Y; Yamazaki, K; Yoshida, Y | 1 |
| McCann, A; Meyer, K; Midttun, Ø; Nygård, O; Tell, G; Ueland, PM; Ulvik, A | 1 |
4 review(s) available for pyridoxal phosphate and kynurenine
| Article | Year |
|---|---|
[Endogenous convulsants (review)].
Topics: Amino Acids; Animals; Carbolines; Cats; Cerebral Cortex; Convulsants; Cysteic Acid; Cysteine; Disease Models, Animal; Dogs; Estrogens; Folic Acid; Homocysteine; Kynurenine; Methionine; Mice; Neurotransmitter Agents; Prostaglandins; Pyridoxal Phosphate; Quinolinic Acid; Quinolinic Acids; Rats; Seizures; Spinal Cord | 1986 |
Xanthurenic acid and xanthurenic acid-8-methyl ether.
Topics: Animals; Blood Glucose; Ethers; Insulin; Kynurenine; Pyridoxal Phosphate; Time Factors; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1968 |
Clinical chemistry of vitamin B6.
Topics: Animals; Biological Assay; Biological Availability; Biological Transport; Chemical Phenomena; Chemistry; Contraceptives, Oral; Female; Humans; Infections; Intestinal Absorption; Kynurenine; Lactation; Liver; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Phosphorylation; Pregnancy; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Radioimmunoassay; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1983 |
Direct and Functional Biomarkers of Vitamin B6 Status.
Topics: Amino Acids; Biomarkers; Body Mass Index; Female; Health Status; Humans; Infant; Infant, Newborn; Inflammation; Kynurenine; Life Style; Male; Metabolome; Metabolomics; Nutritional Status; Pregnancy; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Transaminases; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
3 trial(s) available for pyridoxal phosphate and kynurenine
| Article | Year |
|---|---|
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 status.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Cross-Sectional Studies; Female; Humans; Hydrolases; Kynurenine; Longitudinal Studies; Male; Middle Aged; Norway; Pyridoxal Phosphate; Pyridoxine; ROC Curve; Transaminases; Vitamin B 6 Deficiency; Xanthurenates | 2013 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Metabolome; Pyridoxal Phosphate; Tryptophan; United States; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Female; Humans; Kynurenine; Male; Middle Aged; Pyridoxal Phosphate; Tryptophan; Vitamin B 6 | 2020 |
71 other study(ies) available for pyridoxal phosphate and kynurenine
| Article | Year |
|---|---|
Effect of antibiotics on rat kidney kynurenine aminotransferase activity.
Topics: Animals; Anti-Bacterial Agents; In Vitro Techniques; Kidney; Kinetics; Kynurenine; Male; Pyridoxal Phosphate; Rats; Transaminases | 1979 |
[Tryptophan metabolic indices in allergic dermatoses].
Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prurigo; Pyridoxal Phosphate; Tryptophan; Urticaria; Xanthurenates | 1979 |
Tryptophan metabolism in bladder cancer patients from Copenhagen.
Topics: Denmark; Humans; Kynurenine; Male; Pyridoxal Phosphate; Pyridoxic Acid; Tryptophan; Urinary Bladder Neoplasms | 1979 |
The relative sensitivity of pyridoxal phosphate-dependent enzymes to inhibition in vitro.
Topics: Aspartate Aminotransferases; Glutamate Decarboxylase; In Vitro Techniques; Kynurenine; Pyridoxal Phosphate; Time Factors; Transaminases | 1977 |
In vitro trials to counteract the inhibitory effect of beta-oestradiol and ethynyloestradiol on the B6-dependent kynurenine aminotransferase enzyme.
Topics: Animals; Estrogen Antagonists; Ethinyl Estradiol; Kynurenine; Liver; Male; Manganese; Mice; Progesterone; Pyridoxal Phosphate; Transaminases; Zinc | 1976 |
Studies on the kynurenine adminotransferase activity in rat liver and kidney.
Topics: Animals; In Vitro Techniques; Kidney; Kinetics; Kynurenic Acid; Kynurenine; Liver; Male; Mitochondria; Mitochondria, Liver; Pyridoxal Phosphate; Rats; Transaminases; Xanthurenates | 1976 |
Plasma pyridoxal phosphate levels and tryptophan metabolism in children with burns and scalds.
Topics: Burns; Child; Child, Preschool; Humans; Kynurenic Acid; Kynurenine; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1975 |
Effects of oral contraceptives on tryptophan metabolism and vitamin B6 requirements in women.
Topics: Adult; Contraceptives, Oral; Cystathionine; Female; Humans; Kynurenine; Methionine; Pyridoxal Phosphate; Pyridoxine; Sex Factors; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Relationship between pyridoxal phosphate and some synthetic oestrogens, gonadotropin and thyroxine in their effects on kynurenine hydrolase and kynurenine aminotransferase enzymes of normal mouse liver.
Topics: Animals; Estradiol Congeners; Follicle Stimulating Hormone; Hydrolases; Kynurenine; Liver; Luteinizing Hormone; Male; Mice; Pyridoxal Phosphate; Thyroxine; Transaminases | 1975 |
Regulation of the activity of microbial kynureninase by transamination of the enzyme-bound coenzyme.
Topics: Alanine; Hydrolases; Kynurenine; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Spectrophotometry; Transaminases | 1975 |
Kynurenine and lipid metabolism.
Topics: Animals; Cholesterol; Fatty Acids; Kidney; Kynurenine; Lipid Metabolism; Liver; Male; Myocardium; Phospholipids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains | 1991 |
On kynureninase activity.
Topics: Animals; Apoenzymes; Benzothiazoles; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrolases; Kynurenine; Liver; Magnesium; Male; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Xanthurenates | 1991 |
[Peculiarities of nicotinic acid formation in coronary heart disease with special reference to heart arrhythmias].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Kynurenine; Lipid Metabolism; Male; Microscopy, Electron; Middle Aged; Myocardial Infarction; Myocardium; Niacin; Pyridoxal Phosphate; Ranidae; Rats; Rats, Inbred Strains; Tryptophan | 1988 |
Isolation and characterization of a rat liver enzyme with both cysteine conjugate beta-lyase and kynureninase activity.
Topics: Animals; Antibodies; Carbon-Sulfur Lyases; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrolases; Kynurenine; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1985 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Studies with tryptophan metabolites in vitro. 3. The effect of schistosomicidal drugs on kynureninase and kynurenine transaminase of normal mouse liver.
Topics: Animals; Anti-Infective Agents; Antimony; Benzenesulfonates; Calcium; Imidazoles; In Vitro Techniques; Kynurenic Acid; Kynurenine; Liver; Magnesium; Mice; ortho-Aminobenzoates; Pyridoxal Phosphate; Tartrates; Transaminases; Tryptophan | 1969 |
Effects of steroid conjugates on availability of pyridoxal phosphate for kynureninase and kynurenine aminotransferase activity.
Topics: Animals; Binding Sites; Body Weight; Castration; Depression, Chemical; Diet; Diethylstilbestrol; Estrogens, Conjugated (USP); Female; Hydrolases; Kidney; Kynurenine; Liver; Male; Mitochondria; Mitochondria, Liver; Organ Size; Ovary; Protein Binding; Pyridoxal Phosphate; Rats; Sex Factors; Transaminases; Tryptophan | 1971 |
Evidence for distinct kynureninase and hydroxykynureninase activities in Neurospora crassa.
Topics: Cell-Free System; Chromatography, DEAE-Cellulose; Culture Media; Enzyme Induction; Fluorometry; Hydrolases; Kynurenine; Magnesium Sulfate; Models, Chemical; NAD; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Tryptophan | 1971 |
Effects of steroid and nonsteroid metabolites on enzyme conformation and pyridoxal phosphate binding.
Topics: Animals; Buffers; Castration; Diethylstilbestrol; Estrogens; Female; In Vitro Techniques; Kidney; Kynurenine; Liver; Male; Mitochondria, Liver; Ovary; Protein Binding; Pyridoxal Phosphate; Rats; Steroids; Transaminases; Transferases; Tryptophan; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1969 |
Inversion in the metabolism of D-tryptophan in the rabbit and the rat.
Topics: Aerobiosis; Amination; Anaerobiosis; Animals; Chromatography, Paper; D-Amino-Acid Oxidase; Deamination; Diet; Indoles; Kidney; Kynurenic Acid; Kynurenine; Liver; Male; Organ Specificity; ortho-Aminobenzoates; Oryza; Oxidation-Reduction; Oxygen Consumption; Pyridoxal Phosphate; Pyruvates; Rabbits; Rats; Species Specificity; Stereoisomerism; Tryptophan | 1971 |
On the convulsive action of castrix.
Topics: Animals; Aspartate Aminotransferases; Carboxy-Lyases; Central Nervous System Stimulants; Cholinesterase Inhibitors; Dimethylamines; Glutamates; Hydrolases; Kynurenine; Male; Mice; Oxidoreductases; Phosphotransferases; Pyridoxal Phosphate; Pyridoxine; Pyrimidines; Seizures | 1972 |
Relationship between pyridoxal phosphate and some synthetic oestrogens in their effect on kynurenine hydrolase and kynurenine aminotransferase enzymes of normal mouse liver.
Topics: Animals; Estradiol; Estradiol Congeners; Ethinyl Estradiol; Hydrolases; Kinetics; Kynurenic Acid; Kynurenine; Liver; Male; Mestranol; Mice; Progesterone; Pyridoxal Phosphate; Transaminases | 1974 |
[Comparison of kynureninase activity in various organs of mammals].
Topics: Adult; Aged; Animals; Brain; Cattle; Enzyme Activation; Female; Guinea Pigs; Humans; Hydrolases; Kidney; Kynurenine; Leukocytes; Liver; Lung; Mice; Muscles; Pyridoxal Phosphate; Rats; Skin; Spleen; Swine | 1972 |
Isolation and characterization of an hydroxykynureninase from homogenates of adult mouse liver.
Topics: Animals; Chromatography, DEAE-Cellulose; Hydrolases; In Vitro Techniques; Kinetics; Kynurenine; Liver; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Molecular Weight; ortho-Aminobenzoates; Pyridoxal Phosphate | 1973 |
Properties of crystalline kynureninase from Pseudomonas marginalis.
Topics: Amino Acids; Apoproteins; Autoanalysis; Bacteria; Chromatography, Ion Exchange; Crystallization; Drug Stability; Hydrogen-Ion Concentration; Hydrolases; Hydroxylamines; Kinetics; Kynurenine; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Species Specificity; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Ultracentrifugation | 1973 |
Transamination reaction catalyzed by kynureninase and control of the enzyme activity.
Topics: Amines; Amino Acids; Apoproteins; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Electrophoresis, Paper; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Kynurenine; Ornithine; Pseudomonas; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1973 |
Studies with tryptophan metabolites in vitro. V. Effect of the methanesulphonate derivative of hycanthone (etrenol) and lead acetate on kynureninase and kynurenine transaminase of normal mouse liver.
Topics: Acetates; Anthelmintics; Ethylamines; Hydrolases; Ketones; Kynurenic Acid; Kynurenine; Lead; Liver; ortho-Aminobenzoates; Osmolar Concentration; Pyridoxal Phosphate; Spectrum Analysis; Sulfonic Acids; Sulfur; Transaminases; Tryptophan; Ultraviolet Rays; Xanthenes | 1972 |
[Determination of microliter quantities of kynureninase in human liver].
Topics: Adult; Aged; Biopsy; Enzyme Activation; Female; Humans; Hydrolases; Kynurenine; Liver; Male; Mathematics; Methods; Middle Aged; ortho-Aminobenzoates; Pyridoxal Phosphate; Spectrometry, Fluorescence | 1972 |
Tryptophan metabolism in rheumatoid neuropathies.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Child; Child, Preschool; Electrophysiology; Female; Humans; Kynurenine; Male; Middle Aged; Neurologic Manifestations; Nicotinic Acids; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1972 |
Anergy and tryptophan metabolism in Hodgkin's disease.
Topics: Adolescent; Adult; Age Factors; Amino Acids; Anemia; Antigens; Candida; Coccidioides; Deficiency Diseases; Female; Histoplasmin; Hodgkin Disease; Humans; Kynurenine; Lymphopenia; Male; Middle Aged; Phenylbutyrates; Pyridoxal Phosphate; Sex Factors; Skin Tests; Tryptophan; Tuberculin; Xanthurenates | 1971 |
Crystalline kynureninase from Pseudomonas marginalis.
Topics: Alanine; Ammonium Sulfate; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Crystallization; Electrophoresis, Disc; Hydrolases; Hydroxyapatites; Hydroxylamines; Kynurenine; Molecular Weight; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation | 1971 |
Inactivation of kynureninase by L-alanine.
Topics: Alanine; Borohydrides; Enzyme Activation; Hydrolases; Kinetics; Kynurenine; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Sodium; Spectrophotometry | 1971 |
Abnormalities of tryptophan metabolism and plasma pyridoxal phosphate in Hodgkin's disease.
Topics: Adolescent; Adult; Anemia; Carbon Isotopes; Female; Hodgkin Disease; Humans; Kynurenine; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxine; Skin Tests; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1970 |
Studies on the kynurenine transaminase of Schistocerca gregaria forsk. (Orthoptera, Acrididae).
Topics: Adipose Tissue; Amino Acids; Animals; Female; Horses; Hydrogen-Ion Concentration; Insecta; Ketoglutaric Acids; Kinetics; Kynurenine; Male; Oxaloacetates; Phenylbutyrates; Pyridoxal Phosphate; Pyruvates; Temperature; Transaminases | 1970 |
Studies on the effect of reserpine therapy on the functional capacity of the tryptophan-niacin pathway in smoker and non-smoker males.
Topics: Adult; Aminohippuric Acids; Carboxy-Lyases; Catecholamines; Glucuronates; Humans; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Nicotine; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Reserpine; Smoking; Tryptophan; Xanthurenates | 1970 |
[Vitamin B6 deficiency in patients with leg ulcers and in their family members].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Paper; Female; Humans; Kynurenine; Leg Ulcer; Male; Middle Aged; Pedigree; Pyridoxal Phosphate; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1970 |
The effect of estrogens on pyridoxal phosphate dependent enzymes in patients with cancer of the prostate.
Topics: Alanine Transaminase; Aminohippuric Acids; Aspartate Aminotransferases; Carboxy-Lyases; Chlorotrianisene; Coenzymes; Diethylstilbestrol; Erythrocytes; Glucuronates; Humans; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Neoplasms; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1971 |
Kynurenine metabolism in the developing chick embryo.
Topics: Animals; Chick Embryo; Fluorescence; Hydrolases; Kynurenine; Liver; ortho-Aminobenzoates; Pyridoxal Phosphate; Rats; Transaminases | 1971 |
Studies with tryptophan metabolites in vitro. Kynurenine metabolism in kidneys of mice infested with Schistosoma mansoni.
Topics: Animals; Hydrolases; In Vitro Techniques; Kidney; Kynurenic Acid; Kynurenine; Mice; ortho-Aminobenzoates; Pyridoxal Phosphate; Schistosomiasis; Tryptophan; Urinary Bladder Neoplasms | 1968 |
The influence of sex and estrogens on liver kynureninase and kynurenine aminotransferase in the rat.
Topics: Animals; Benzoates; Depression, Chemical; Estradiol; Estrogens; Female; Hydrolases; Kynurenine; Liver; Male; Mestranol; Norethynodrel; Progesterone; Progestins; Pyridoxal Phosphate; Rats; Sex Factors; Stimulation, Chemical; Transaminases | 1969 |
A study of tryptophan metabolism in psychotic children.
Topics: Autoradiography; Carbon Isotopes; Child; Child, Preschool; Female; Humans; Kynurenine; Male; Metabolic Diseases; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Schizophrenia, Childhood; Tryptophan; Xanthurenates | 1966 |
Biochemical and physiological changes in vitamin B6 deficiency.
Topics: Alanine Transaminase; Anemia, Hypochromic; Central Nervous System Diseases; Cysteine; Erythrocytes; Humans; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; Pyridoxal Phosphate; Pyridoxine; Serotonin; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1967 |
Studies with tryptophan metabolites in vitro. Kynurenine metabolism in liver homogenates of normal and Schistosoma mansoni-infested mice.
Topics: Animals; Kinetics; Kynurenine; Liver; Mice; ortho-Aminobenzoates; Perfusion; Pyridoxal Phosphate; Pyridoxine; Schistosomiasis; Tryptophan | 1967 |
Studies with tryptophan metabolites in vitro. II. Effect of tartar emetic on kynurenine metabolism by normal mouse liver.
Topics: Animals; In Vitro Techniques; Kynurenine; Liver; Mice; ortho-Aminobenzoates; Pyridoxal Phosphate; Spectrophotometry; Tartrates; Transaminases | 1967 |
Studies on the intracellular change of vitamin B6 content and kynurenine aminotransferase activity in the vitamin B6 deficient rat.
Topics: Animals; Kidney; Kynurenine; Liver; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Vitamin B 6 Deficiency | 1967 |
Effect of natural oestrogens on tryptophan metabolism: evidence for interference of oestrogens with kynureninase.
Topics: Aged; Estradiol; Estriol; Estrogens; Female; Humans; Hydrolases; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan | 1980 |
The effect of drugs on vitamin B6 function in the rat.
Topics: Animals; In Vitro Techniques; Isoniazid; Kynurenine; Lyases; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1980 |
Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase.
Topics: Animals; Chlorides; COS Cells; Flavin-Adenine Dinucleotide; Humans; Hydrogen-Ion Concentration; Ions; Kinetics; Kynurenine; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Molecular Weight; NAD; NADP; NADPH Oxidases; Oxidation-Reduction; Peroxides; Pyridoxal Phosphate; Recombinant Fusion Proteins; Substrate Specificity; Thermodynamics; Transfection | 2000 |
Kynurenine-transaminase, kynureninase and the increase of xanthurenic acid excretion.
Topics: Humans; Hydrolases; Kynurenine; Oxidoreductases; Pyridoxal Phosphate; Transaminases; Vitamin B 6 Deficiency; Xanthurenates | 1962 |
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Kynurenine; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Multiple Myeloma; ortho-Aminobenzoates; Phenylbutazone; Polycythemia Vera; Proteins; Pyridoxal Phosphate; Pyridoxine; Sarcoma; Severe Combined Immunodeficiency; Tryptophan; Urine; Xanthurenates | 1964 |
PYRIDOXAMINE-OXALOACETIC TRANSAMINASE OF RAT KIDNEY.
Topics: Acetates; Arsenicals; Aspartate Aminotransferases; Buffers; Chromatography; Diethylstilbestrol; Diphosphates; Glycerophosphates; Keto Acids; Kidney; Kynurenine; Phosphates; Potassium; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Rats; Research; Transaminases | 1964 |
Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts.
Topics: Biomarkers; Case-Control Studies; Coronary Disease; Homocysteine; Humans; Kynurenine; Neopterin; Prognosis; Pyridoxal Phosphate; Tryptophan | 2003 |
Crystal structures of Aedes aegypti alanine glyoxylate aminotransferase.
Topics: Aedes; Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Kynurenine; Models, Molecular; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity; Transaminases; Xanthurenates | 2006 |
Biochemical and structural properties of mouse kynurenine aminotransferase III.
Topics: Amination; Animals; Catalysis; Catalytic Domain; Crystallography, X-Ray; Glutamine; Humans; Hydrogen-Ion Concentration; Kinetics; Kynurenine; Mice; Protein Structure, Secondary; Protein Subunits; Pyridoxal Phosphate; Structure-Activity Relationship; Substrate Specificity; Temperature; Transaminases | 2009 |
Quantum mechanics/molecular mechanics (QM/MM) modeling of the irreversible transamination of L-kynurenine to kynurenic acid: the round dance of kynurenine aminotransferase II.
Topics: Humans; In Vitro Techniques; Isoenzymes; Kynurenic Acid; Kynurenine; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Structure; Pyridoxal Phosphate; Quantum Theory; Thermodynamics; Transaminases | 2009 |
Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation.
Topics: Adult; Aged; C-Reactive Protein; Coronary Disease; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Pyridoxal Phosphate; Vitamin B 6 | 2011 |
Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine.
Topics: Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Calorimetry; Catalytic Domain; Crystallography, X-Ray; Humans; Ketoglutaric Acids; Kinetics; Kynurenine; Models, Molecular; Protein Binding; Protein Structure, Secondary; Pyridoxal Phosphate; Pyrococcus horikoshii; Structural Homology, Protein; Surface Properties; Thermodynamics; Transaminases | 2012 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Multivariate Analysis; Postprandial Period; Pyridoxal Phosphate; Serine; Tryptophan; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2013 |
Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond.
Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Kynurenine; Male; Pyridoxal Phosphate; Vitamin B 6 Deficiency; Xanthurenates | 2013 |
Evidence for increased catabolism of vitamin B-6 during systemic inflammation.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Inflammation; Kynurenine; Linear Models; Longitudinal Studies; Male; Middle Aged; Neopterin; Norway; Oxidative Stress; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; ROC Curve; Tryptophan; Vitamin B 6 | 2014 |
Vitamins B2 and B6 as determinants of kynurenines and related markers of interferon-γ-mediated immune activation in the community-based Hordaland Health Study.
Topics: Aged; Biomarkers; Cohort Studies; Diet; Female; Humans; Immunity; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Surveys and Questionnaires; Tryptophan; Vitamin B 6 | 2014 |
Markers of vitamin B6 status and metabolism as predictors of incident cancer: the Hordaland Health Study.
Topics: Aged; Biomarkers; Female; Follow-Up Studies; Health Surveys; Humans; Incidence; Kynurenine; Male; Middle Aged; Multivariate Analysis; Neoplasms; Norway; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Pyridoxal Phosphate; Pyridoxic Acid; Risk Assessment; Risk Factors; Vitamin B 6; Xanthurenates | 2015 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Male; Metformin; Middle Aged; Prediabetic State; Pyridoxal Phosphate; Stress, Physiological; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Inflammation; Interleukin-10; Kynurenine; Linear Models; Male; Neopterin; ortho-Aminobenzoates; Pyridoxal Phosphate; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Young Adult | 2016 |
Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Nutritional Status; Odds Ratio; Oxidative Stress; Prospective Studies; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Sweden; Vitamin B 6; Vitamin B 6 Deficiency; Xanthurenates | 2017 |
Fragment Screening of Human Kynurenine Aminotransferase-II.
Topics: Drug Design; Enzyme Inhibitors; Humans; Kynurenic Acid; Kynurenine; Pyridoxal Phosphate; Small Molecule Libraries; Surface Plasmon Resonance; Transaminases | 2018 |
A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer.
Topics: 3-Hydroxyanthranilic Acid; Biomarkers; Case-Control Studies; China; Female; Humans; Kynurenine; Male; Middle Aged; Odds Ratio; Pancreatic Neoplasms; Prospective Studies; Pyridoxal Phosphate; Risk Factors; Vitamin B 6 | 2018 |
Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα Inhibitors.
Topics: Adult; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Female; Humans; Kynurenine; Longitudinal Studies; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Vitamin B 6; Vitamin B 6 Deficiency; Xanthurenates | 2019 |
Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues.
Topics: Animals; Brain; Computational Biology; Glycyrrhizic Acid; Humans; Isoenzymes; Kynurenic Acid; Kynurenine; Mice; Molecular Docking Simulation; Pyridoxal Phosphate; Receptors, Nicotinic; Transaminases | 2019 |