pyridoxal phosphate has been researched along with glycine in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (50.82) | 18.7374 |
| 1990's | 20 (16.39) | 18.2507 |
| 2000's | 24 (19.67) | 29.6817 |
| 2010's | 15 (12.30) | 24.3611 |
| 2020's | 1 (0.82) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Florianowicz, T; Galas, E | 1 |
| Horton, R; Meldrum, B; Sawaya, C | 1 |
| Baron, J; Condie, LW; Tephly, TR | 1 |
| Aprison, MH; Daly, EC; Nadi, NS | 1 |
| Miles, EW | 2 |
| Schachman, HK; Wall, KA | 1 |
| Beart, PM; Bilal, K | 1 |
| Beeler, T; Churchich, JE | 1 |
| Costa, MT; Mondovì, B; Sabatini, S; Turini, P | 1 |
| Dalling, DK; Grant, DM; Horton, WJ; Sagers, RD | 1 |
| Ikeda, M; Maeda, M; Tsuji, A | 1 |
| Gariani, LS; Malthouse, JP; Milne, JJ | 1 |
| Kojiro, CL; Lewis, SD; Marceau, M; Mountjoy, K; Shafer, JA | 1 |
| Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM | 1 |
| Lewis, SD; Marceau, M; Shafer, JA | 1 |
| Davis, L; Eckenrode, F; Fubara, B; Tressel, T | 1 |
| Iyoda, K; Miyake, S; Narusawa, K; Ohtahara, S; Terasaki, T; Yamatogi, Y | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Davies, WE; Fisher, SK | 1 |
| Nieradt-Hiebsch, C; Rapoport, S; Thamm, R | 1 |
| Bottomley, SS; Self, J; Tanaka, M | 1 |
| Bottomley, SS; Smithee, GA | 1 |
| Kikuchi, G; Motokawa, Y | 1 |
| Kikuchi, G; Kochi, H; Sato, N; Sato, T | 1 |
| Goriukhina, TA; Lebedeva, SB | 1 |
| Bruin, WJ; Frantz, BM; Sallach, HJ | 1 |
| Kikuchi, G; Kochi, H | 1 |
| Turner, JM; Willetts, AJ | 1 |
| Aoki, Y; Nakao, K; Takaku, F; Wada, O; Yano, Y | 1 |
| Blanck, TJ; Dunathan, HC; Hindenlang, DM; Kallen, RG; Ulevitch, RJ; Voet, JG | 1 |
| Ellegaard, J; Esmann, V | 1 |
| Kazarinoff, MN; McCormick, DB | 1 |
| Evered, DF; Hargreaves, BM | 1 |
| Banaschak, H; Woelke, D | 1 |
| Koga, T; Ressler, C | 1 |
| Dunathan, HC | 1 |
| Goldberg, A; Morrow, JJ; Urata, G | 1 |
| Mole, KH; Shepherd, DM | 1 |
| Hammaker, LE; Marver, HS; Scholnick, PL | 1 |
| Cheng, CF; Haslam, JL | 1 |
| Asmar, JA; Daghir, NJ; Sifri, M | 1 |
| Avery, MD; Lupien, PJ | 1 |
| Akhtar, M; Jordan, PM | 1 |
| Kumagai, H; Nagate, T; Yamada, H; Yoshida, H | 1 |
| Ekstrom, CG; Felty, WL; Leussing, DL | 1 |
| Hiraga, K; Kikuchi, G; Kochi, H; Motokawa, Y | 1 |
| Thomas, JH; Tudball, N | 1 |
| Diller, A; Schirch, LV | 1 |
| Neuwirt, J; Ponka, P | 1 |
| Bridgers, WF | 1 |
| Gershoff, SN; Runyan, TJ | 1 |
| Klein, SM; Sagers, RD | 2 |
| Finseth, F; Sizer, IW | 1 |
| Kikuchi, G; Kochi, H; Motokawa, Y; Sato, T | 1 |
| Lachmann, G; Schnackerz, KD | 1 |
| Mozzarelli, A; Ottonello, S; Rossi, GL; Schirch, L | 1 |
| Burnett, G; Marcotte, P; Walsh, C | 1 |
| Barber, MJ; Ferreira, GC; Hafez, O; Hunter, GA; Vajapey, U | 1 |
| Fukui, T; Sekimoto, T; Tanizawa, K | 1 |
| Douce, R; Droux, M; Ravanel, S | 1 |
| Ferreira, GC; Gong, J | 1 |
| Dekker, EE; Marcus, JP | 1 |
| Kurosawa, M; Murakoshi, I; Saito, K | 1 |
| Abeles, RH; Xu, Y | 1 |
| Winkler, ME; Zhao, G | 1 |
| Gekko, K; Hayashi, H; Kagamiyama, H; Ohmae, E; Tamura, Y; Ueno, H | 1 |
| Barber, MJ; Ferreira, GC; Gong, J; Kay, CJ | 1 |
| Ikemi, M; Kataoka, M; Miyoshi, T; Morikawa, T; Nishi, K; Shimizu, S; Wada, M; Yamada, H | 1 |
| Bossa, F; Delle Fratte, S; Maras, B; Schirch, V; White, RH | 1 |
| Fitzpatrick, TB; Malthouse, JP | 2 |
| Douce, R; Gakière, B; Job, D; Ravanel, S | 1 |
| Christen, P; Fitzpatrick, TB; Gramatikova, SI; Mahon, MM; Malthouse, JP | 1 |
| Li, C; Peoples, RW | 1 |
| Ro, HS; Wilson Miles, E | 1 |
| Kazanina, G; Radaev, S; Scarsdale, JN; Schirch, V; Wright, HT | 1 |
| Goto, K; Inutsuka, M; Izumi, T; Maeda, T | 1 |
| Berkowitz, DB; McFadden, JM; Sloss, MK | 1 |
| Clausen, T; Holt, SC; Huber, R; Krupka, HI | 1 |
| Callahan, B; Chen, Y; Huai, Q; Ke, H; Li, N; Xia, Y | 1 |
| Akaike, N; Jang, IS; Kubota, H; Rhee, JS | 1 |
| Laube, B | 1 |
| Hilvert, D; Seebeck, FP | 1 |
| GREENBERG, DM; LIN, SC | 1 |
| BLAKLEY, RL | 1 |
| HARRINGTON, H; SAKAMI, W | 1 |
| BONOMI, U; TENCONI, LT | 1 |
| GREENBERG, DM; MALKIN, LI | 1 |
| Choi, HP; Hong, JW; Rhee, KH; Sung, HC | 1 |
| Chang, WH; Chang, Y; Chen, YC; Sung, HW | 1 |
| Berkowitz, DB; Maiti, G | 1 |
| Amyes, TL; Malthouse, JP; NíBeilliú, ME; Richard, JP; Toth, K | 1 |
| Kao, CL; Karthikeyan, S; Liu, HW; Robinson, H; Tao, Z; Zhang, H; Zhao, Z; Zhou, Q | 1 |
| Coats, BS; Davis, SR; Gregory, JF; Quinlivan, EP; Scheer, JB; Stacpoole, PW | 1 |
| Capitani, G; Eliot, AC; Grütter, MG; Kirsch, JF; Tschopp, M | 1 |
| Astner, I; Heinz, DW; Jahn, D; Schubert, WD; Schulze, JO; van den Heuvel, J | 1 |
| Ferreira, GC; Hunter, GA; Turbeville, TD; Zhang, J | 1 |
| Arimura, Y; Eto, K; Ishibashi, H; Nabekura, J; Noda, M | 1 |
| Gilbert, LR; Gregory, JF; Lamers, Y; Stacpoole, PW; Williamson, J | 1 |
| Chambers, LJ; Michel, AD; Walter, DS | 1 |
| Clay, WC; Condreay, JP; Hall, M; Holbrook, J; Livermore, D; Michel, AD; Ng, SW; Roman, S; Senger, S; Thompson, K | 1 |
| Appaji Rao, N; Bhavani, BS; Bisht, S; Kaul, P; Murthy, MR; Prakash, V; Rajaram, V; Savithri, HS | 1 |
| Fesko, K; Giger, L; Hilvert, D | 1 |
| Crugeiras, J; Richard, JP; Rios, A; Riveiros, E | 1 |
| Baxter, GF; Elsey, DJ; Fowkes, RC | 1 |
| Choudhury, SR; Roy, S; Sengupta, DN; Singh, SK | 1 |
| Demidkina, TV; Faleev, NG; Gogoleva, OI; Komissarov, VV; Koulikova, VV; Morozova, EA; Timofeev, VP; Tkachev, YV; Tsvetikova, MA; Zakomirdina, LN | 1 |
| Amyes, TL; Crugeiras, J; Richard, JP; Rios, A | 1 |
| Andi, B; Cook, PF; Schnackerz, KD | 1 |
| Fujita, T; Kumamoto, E; Liu, T | 1 |
| Toney, MD | 1 |
| Cai, B; Cui, QH; Fan, X; Geng, B; Gong, Y; Liao, F; Tang, C; Xu, GH; Yang, J; Zeng, Q; Zheng, Y | 1 |
| Anufrieva, NV; Demidkina, TV; Faleev, NG; Fedorova, OS; Kuznetsov, NA; Kuznetsova, AA; Morozova, EA; Nikulin, AD; Revtovich, SV | 1 |
| Gruber, K; Mink, D; Oberdorfer, G; Riegler-Berket, L; Schürmann, M; Steinkellner, G; Uhl, MK; van Assema, F | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Ashida, H; Hirato, Y; Nishimura, K; Tanaka, H; Tanigawa, M; Tokuhisa, M | 1 |
| Burgering, B; Gerrits, J; Jans, JJ; Pras-Raves, ML; Prinsen, H; Ramos, RJ; van der Ham, M; Verhoeven-Duif, NM; Willemsen, M | 1 |
| Anufrieva, NV; Bazhulina, NP; Belyi, YF; Demidkina, TV; Hayashi, H; Kotlov, MI; Koval, VS; Kulikova, VV; Morozova, EA; Revtovich, SV | 1 |
| El Baze, A; Knizia, D; Lakhssassi, A; Lakhssassi, N; Meksem, J; Meksem, K | 1 |
5 review(s) available for pyridoxal phosphate and glycine
| Article | Year |
|---|---|
Stereochemical aspects of pyridoxal phosphate catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine Transaminase; Allosteric Regulation; Amino Acids; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Cystathionine; Glycine; Homoserine; Kinetics; Lyases; Models, Biological; Molecular Conformation; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Schiff Bases; Serine; Structure-Activity Relationship; Threonine; Transaminases; Transferases | 1971 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
The PLP cofactor: lessons from studies on model reactions.
Topics: Catalysis; Glycine; Models, Chemical; Pyridoxal Phosphate | 2011 |
(31)P NMR spectroscopy senses the microenvironment of the 5'-phosphate group of enzyme-bound pyridoxal 5'-phosphate.
Topics: Catalysis; Enzymes; Glycine; Magnetic Resonance Spectroscopy; Phosphorus Isotopes; Pyridoxal Phosphate | 2011 |
Controlling reaction specificity in pyridoxal phosphate enzymes.
Topics: Biocatalysis; Enzymes; Glycine; Models, Molecular; Oxidation-Reduction; Protons; Pyridoxal Phosphate; Stereoisomerism | 2011 |
1 trial(s) available for pyridoxal phosphate and glycine
| Article | Year |
|---|---|
Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine.
Topics: Adult; Carbon Isotopes; Decarboxylation; Female; Folic Acid; Glycine; Humans; Isotope Labeling; Leucine; Male; Pyridoxal Phosphate; Tritium; Vitamin B 12 | 2007 |
116 other study(ies) available for pyridoxal phosphate and glycine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
L-Glutamate-glyoxylate aminotransferase in Lactobacillus plantarum.
Topics: Azides; Cell-Free System; Cyanides; Edetic Acid; Glutamates; Glycine; Glyoxylates; Hydrogen-Ion Concentration; Hydroxylamines; Isoniazid; Ketoglutaric Acids; Lactobacillus; Magnesium; Pyridoxal Phosphate; Temperature; Transaminases | 1975 |
Transmitter synthesis and convulsant drugs: effects of pyridoxal phosphate antagonists and allylglycine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; In Vitro Techniques; Mice; Mice, Inbred DBA; Neurotransmitter Agents; Pyridoxal Phosphate | 1978 |
Studies on adrenal delta-aminolevulinic acid synthetase.
Topics: 5-Aminolevulinate Synthetase; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Allylisopropylacetamide; Animals; Cattle; Cytosol; Dicarbethoxydihydrocollidine; Glycine; Liver; Male; Microsomes; Mitochondria; Organ Specificity; Pyridoxal Phosphate; Rats; Species Specificity; Starvation; Succinates | 1976 |
Regional distribution and properties of the glycine cleavage system within the central nervous system of the rat: evidence for an endogenous inhibitor during in vitro assay.
Topics: Amino Acids; Animals; Brain; Dithiothreitol; Edetic Acid; Glycine; Glycine Hydroxymethyltransferase; Medulla Oblongata; Mesencephalon; NAD; Organ Specificity; Pons; Pyridoxal Phosphate; Rats; Spinal Cord; Succinate Dehydrogenase; Telencephalon; Tetrahydrofolates | 1976 |
Effects of modification of the beta 2 subunit and of the alpha2beta2 complex of tryptophan synthase by alpha-cyanoglycine, a substrate analog.
Topics: Catalysis; Dialysis; Enzyme Activation; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mathematics; Nitriles; Pyridoxal Phosphate; Serine; Spectrophotometry; Temperature; Tryptophan Synthase; Urea | 1975 |
Primary structure and properties of an inactive mutant aspartate transcarbamoylase.
Topics: Amino Acid Sequence; Aspartate Carbamoyltransferase; Aspartic Acid; Circular Dichroism; Escherichia coli; Glycine; Kinetics; Macromolecular Substances; Mutation; Peptide Fragments; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet | 1979 |
Allylglycine: intranigral effects and reappraisal of actions on the GABA system.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; Kinetics; Male; Neurotoxins; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Substantia Nigra | 1979 |
Photodynamic properties of pyridoxal phosphate bound to cystathionase-gamma-lyase.
Topics: Allyl Compounds; Apoenzymes; Cystathionine gamma-Lyase; Glycine; Light; Lyases; Protein Binding; Pyridoxal Phosphate; Spectrophotometry | 1978 |
Inhibition of beef plasma amine oxidase activity by glycine.
Topics: Animals; Binding Sites; Cattle; Glycine; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridoxal Phosphate; Spectrum Analysis | 1978 |
Carbon 13 NMR study of nonenzymatic reactions of pyridoxal 5'-phosphate with selected amino acids and of related reactions.
Topics: Alanine; Amino Acids; Ammonia; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Formaldehyde; Glycine; Magnetic Resonance Spectroscopy; Molecular Conformation; Pyridoxal Phosphate; Pyridoxamine; Sarcosine; Structure-Activity Relationship | 1976 |
A fluorophotometric method for the determination of pyridoxal and its phosphate by using glycine and zinc(II) ion.
Topics: Glycine; Methods; Pyridoxal; Pyridoxal Phosphate; Spectrometry, Fluorescence; Zinc | 1976 |
A new type of pyridoxal-P enzyme catalyzed reaction: the conversion of beta, gamma-unsaturated amino acids to saturated alpha-keto acids by tryptophan synthase.
Topics: Amino Acids; Binding Sites; Borohydrides; Gas Chromatography-Mass Spectrometry; Glycine; Hydroxy Acids; Kinetics; L-Lactate Dehydrogenase; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Tryptophan Synthase; Vinyl Compounds | 1975 |
A comparative study of the kinetics and stereochemistry of the serine hydroxymethyltransferase- and tryptophan synthase-catalysed exchange of the pro-2R and pro-2S protons of glycine.
Topics: Animals; Catalysis; Cattle; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Liver; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Salmonella typhimurium; Stereoisomerism; Substrate Specificity; Tryptophan Synthase | 1991 |
Disruption of active site interactions with pyridoxal 5'-phosphate and substrates by conservative replacements in the glycine-rich loop of Escherichia coli D-serine dehydratase.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Dithionitrobenzoic Acid; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; L-Serine Dehydratase; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Trypsin | 1990 |
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases | 1988 |
The glycine-rich region of Escherichia coli D-serine dehydratase. Altered interactions with pyridoxal 5'-phosphate produced by substitution of aspartic acid for glycine.
Topics: Algorithms; Aspartic Acid; Circular Dichroism; Escherichia coli; Glycine; L-Serine Dehydratase; Pyridoxal Phosphate; Structure-Activity Relationship | 1988 |
Purification and properties of aminoacetone synthetase from beef liver mitochondria.
Topics: Acetyl Coenzyme A; Acetyltransferases; Alcohol Oxidoreductases; Amino Acids; Animals; Carbon Dioxide; Cattle; Coenzyme A; Glycine; Isoelectric Point; Macromolecular Substances; Mitochondria, Liver; Molecular Weight; Pyridoxal Phosphate | 1986 |
[A long-term follow-up study on a case with glycine encephalopathy].
Topics: Amino Acid Metabolism, Inborn Errors; Brain Diseases, Metabolic; Child, Preschool; Diazepam; Electroencephalography; Follow-Up Studies; Glycine; Humans; Infant; Infant, Newborn; Male; Myoclonus; Pyridoxal Phosphate; Spasms, Infantile | 1988 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Some properties of guinea pig brain glutamate decarboxylase and its inhibition by the convulsant allylglycine (2-amino-4-pentenoic acid).
Topics: Aging; Allyl Compounds; Amino Acids; Animals; Anions; Brain; Carbon Radioisotopes; Carboxy-Lyases; Cations, Divalent; Cations, Monovalent; Central Nervous System Stimulants; Chromatography, Gel; Cytosol; Dialysis; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Pyridoxal Phosphate; Rats; Semicarbazides; Species Specificity; Ultracentrifugation | 1974 |
[The effect of higher temperatures on the metabolism of rabbits].
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Coenzyme A; Cytochromes; Glutarates; Glycine; Hydrogen-Ion Concentration; Oxidoreductases; Pyridoxal Phosphate; Rabbits; Reticulocytes; Temperature | 1968 |
Delta-aminolevulinic acid synthetase activity in normal human bone marrow and in patients with idiopathic sideroblastic anemia.
Topics: 5-Aminolevulinate Synthetase; Aged; Anemia, Sideroblastic; Bone Marrow; Carbon Radioisotopes; Chromatography, Ion Exchange; Edetic Acid; Glycine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Kinetics; Levulinic Acids; Middle Aged; Pyridoxal Phosphate; Time Factors | 1973 |
Characterization and measurement of delta-aminolaevulinate synthetase in bone marrow cell mitochondria.
Topics: Acyltransferases; Amino Acids; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Coenzyme A; Edetic Acid; Glycine; Heme; Hemoglobins; Hot Temperature; Iron Isotopes; Ketoglutaric Acids; Levulinic Acids; Lyases; Magnesium; Methods; Microchemistry; Microscopy, Electron; Mitochondria; NAD; Porphyrins; Pyridoxal Phosphate; Rabbits; Succinate Dehydrogenase; Succinates | 1968 |
Glycine metabolism by rat liver mitochondria. II. Methylene tetrahydrofolate as the direct on carbon donor in the reaction of glycine synthesis.
Topics: Animals; Arsenic; Carbon; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Time Factors; Transferases | 1969 |
Glycine metabolism by rat liver mitochondria. 3. The glycine cleavage and the exchange of carboxyl carbon of glycine with bicarbonate.
Topics: Ammonia; Animals; Arsenic; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Folic Acid; Glycine; In Vitro Techniques; Kinetics; Mitochondria, Liver; NAD; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Transferases | 1969 |
[Isoenzyme spectrum of serine transoxymethylase in the liver and in hepatomas].
Topics: Agar; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Electrophoresis; Gels; Glycine; Isoenzymes; Liver; Liver Neoplasms; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Proteins; Pyridoxal Phosphate; Rats; Serine; Spectrophotometry; Tetrahydrofolates; Transferases | 1973 |
The occurrence of a glycine cleavage system in mammalian brain.
Topics: Animals; Brain; Carbon Dioxide; Carbon Isotopes; Cats; Cattle; Digitonin; Dithiothreitol; Dogs; Enzyme Activation; Glycine; Male; Mitochondria; Multienzyme Complexes; NAD; Pyridoxal Phosphate; Rabbits; Rats; Serine; Subcellular Fractions; Swine; Tetrahydrofolates | 1973 |
Reactions of glycine synthesis and glycine cleavage catalyzed by extracts of Arthrobacter globiformis grown on glycine.
Topics: Ammonium Chloride; Arthrobacter; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Cell-Free System; Folic Acid; Formaldehyde; Glutathione; Glycine; Ion Exchange Resins; Kinetics; Mitochondria, Liver; NAD; NADP; Pyridoxal Phosphate; Serine; Sulfhydryl Compounds | 1969 |
L-Threonine acetaldehyde-lyase in a strain of Bacillus subtilis.
Topics: Acetates; Aldehyde-Lyases; Bacillus subtilis; Carboxy-Lyases; Chromatography, Gel; Folic Acid; Glycine; Hydrazines; Hydrogen-Ion Concentration; Isoniazid; Kinetics; L-Serine Dehydratase; NAD; NADP; Phosphoric Acids; Pyridoxal Phosphate; Serine; Stereoisomerism; Threonine; Transferases | 1971 |
-Aminolevulinic acid synthetase activity of human bone marrow erythroid cells in various hematological disorders.
Topics: 5-Aminolevulinate Synthetase; Anemia, Hypochromic; Anemia, Sideroblastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Coenzyme A; Edetic Acid; Erythrocytes; Glycine; Hematologic Diseases; Hematopoietic Stem Cells; Heme; Humans; Hydrogen-Ion Concentration; Ketoglutaric Acids; Levulinic Acids; Magnesium; Porphyrias; Pyridoxal Phosphate; Thalassemia | 1972 |
The stereochemistry of pyridoxal phosphate enzymes. The absolute stereochemistry of cofactor C' 4 protonation in the transamination of holoserine hydroxymethylase by D-alanine.
Topics: Alanine; Aldehydes; Amination; Amino Acids; Animals; Chemical Phenomena; Chemistry; Glycine; Isomerism; Liver; Phosphoric Acids; Protons; Pyridoxal Phosphate; Pyridoxamine; Pyruvates; Serine; Sheep; Tetrahydrofolates; Transaminases; Transferases; Tritium | 1973 |
Folate activity of human lymphocytes determined by measurement of serine synthesis.
Topics: Carbon Dioxide; Carbon Isotopes; Chromatography, Thin Layer; Citric Acid Cycle; Folic Acid; Folic Acid Deficiency; Formates; Glucose; Glycine; Humans; In Vitro Techniques; Lymphocytes; Methionine; Methods; Protein Binding; Pyridoxal Phosphate; RNA; Serine; Tetrahydrofolates | 1973 |
N-(5'-phospho-4'-pyridoxyl)amines as substrates for pyridoxine (pyridoxamine) 5'-phosphate oxidase.
Topics: Amino Acid Oxidoreductases; Amino Acids; Ammonium Sulfate; Animals; Calcium Phosphates; Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Ethanol; Glycine; Kinetics; Liver; Models, Chemical; Organophosphorus Compounds; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Rabbits; Structure-Activity Relationship | 1973 |
Metabolism of omega-amino acids by rat tissues in vitro.
Topics: Alanine; Amino Acids; Aminobutyrates; Aminocaproates; Aminoisobutyric Acids; Animals; Brain; Caprylates; Cyclohexanecarboxylic Acids; Glycine; Intestinal Mucosa; Kidney; Kinetics; Liver; Male; Methionine; Pyridoxal Phosphate; Rats; Schiff Bases; Spectrophotometry, Ultraviolet; Valerates; Valine | 1973 |
[Effect of hydrazinoacetic acid on the incorporation of glycine in E. coli].
Topics: Acetates; Carbon Isotopes; Depression, Chemical; Escherichia coli; Glycine; Hydrazines; Pyridoxal Phosphate | 1968 |
-cyanoamino acids and related nitriles as inhibitors of glutamate decarboxylase.
Topics: Acetates; Amino Acids; Aminobutyrates; Animals; Carbon Isotopes; Carboxy-Lyases; Chickens; Cyanides; Depression; Escherichia coli; Glutamate Dehydrogenase; Glutarates; Glycine; Humans; Hypnotics and Sedatives; Infrared Rays; Kinetics; Nitriles; Propionates; Pyridoxal Phosphate; Seizures; Spectrophotometry; Structure-Activity Relationship; Succinates; Valerates | 1971 |
The effect of lead and ferrous and ferric iron on delta-aminolaevulic acid synthetase.
Topics: Amino Acids; Animals; Chickens; Coenzyme A; Edetic Acid; Erythrocytes; Glycine; In Vitro Techniques; Iron; Ketoglutaric Acids; Lead; Levulinic Acids; Ligases; Magnesium; Pyridoxal Phosphate | 1969 |
Inhibition of histidine decarboxylases in vitro.
Topics: Amino Acids; Animals; Carboxy-Lyases; Dialysis; Female; Glycine; Guinea Pigs; Histidine; Hydrazines; Hydroxylamines; Imidazoles; In Vitro Techniques; Isoquinolines; Kidney; Phenethylamines; Phenylalanine; Propionates; Protein Binding; Pyridoxal Phosphate; Rats; Spectrum Analysis; Stomach; Ultraviolet Rays | 1972 |
Soluble -aminolevulinic acid synthetase of rat liver. II. Studies related to the mechanism of enzyme action and hemin inhibition.
Topics: 5-Aminolevulinate Synthetase; Acyltransferases; Animals; Binding Sites; Carbon Isotopes; Coenzyme A; Cytoplasm; Ethers; Feedback; Glycine; Heme; Kinetics; Liver; Male; Models, Chemical; Porphyrins; Pyridoxal Phosphate; Rats; Schiff Bases; Solubility; Structure-Activity Relationship; Succinates; Sulfhydryl Compounds; Sulfhydryl Reagents | 1972 |
A kinetic investigation of the interaction of serine transhydroxymethylase with glycine.
Topics: Animals; Glycine; Kinetics; Liver; Models, Chemical; Oscillometry; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Temperature; Tetrahydrofolates; Transferases; Ultraviolet Rays | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
Cholesterol metabolism and vitamin B 6 . IV. Synthesis of cholic acid conjugates in vitamin B 6 -deficient rats.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cholesterol; Chromatography, Thin Layer; Diet; Glycine; In Vitro Techniques; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Taurine; Time Factors; Vitamin B 6 Deficiency | 1971 |
The mechanism of action of serine transhydroxymethylase.
Topics: Folic Acid; Formaldehyde; Glycine; Models, Chemical; Pyridoxal Phosphate; Serine; Transferases; Tritium | 1970 |
Crystalline threonine aldolase from Candida humicola.
Topics: Acetaldehyde; Aldehyde-Lyases; Candida; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Electrophoresis, Disc; Glycine; Hydrogen-Ion Concentration; Methods; Molecular Weight; Pyridoxal Phosphate; Serine; Spectrum Analysis; Threonine; Ultracentrifugation; Ultraviolet Rays | 1970 |
Equilibrium studies involving Schiff base complexes. The zinc(II)--pyridoxal phosphate-glycine and -alpha-alanine systems.
Topics: Alanine; Glycine; Imines; Pyridoxal Phosphate; Zinc | 1970 |
Evidence for the presence of a protein-bound intermediate in the cleavage and the synthesis of glycine.
Topics: Acetone; Animals; Carbon Isotopes; Chromatography, Gel; Dihydrolipoamide Dehydrogenase; Electron Transport; Ethylmaleimide; Folic Acid; Glycine; Hydrogen; Mitochondria, Liver; Models, Biological; Models, Chemical; Protein Binding; Proteins; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Sulfides; Transferases | 1970 |
The alpha beta-elimination of L-serylglycine O-sulphate and related dipeptides.
Topics: Catalysis; Copper; Dipeptides; Glycine; Pyridoxal Phosphate; Serine; Sulfates | 1970 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
Regulation of iron entry into reticulocytes. II. Relationship between hemoglobin synthesis and entry of iron into reticulocytes.
Topics: Animals; Biological Transport; Carbon Isotopes; Cell Membrane; Chloramphenicol; Cycloheximide; Emetine; Fluorides; Globins; Glycine; Heme; Hemoglobins; In Vitro Techniques; Iron; Iron Isotopes; Isoniazid; Penicillamine; Puromycin; Pyridoxal Phosphate; Rabbits; Reticulocytes; Tryptamines | 1971 |
Serine transhydroxymethylase in developing mouse brain.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Carbon Isotopes; Folic Acid; Formaldehyde; Glycine; Mice; Pyridoxal Phosphate; Serine; Tissue Extracts; Transferases | 1968 |
Glycine metabolism in vitamin B6-deficient and deoxypyridoxine-treated rats.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Glycine; Glycolates; Glyoxylates; In Vitro Techniques; Kidney; Liver; Male; Methanol; Muscle Proteins; Muscles; Pyridines; Pyridoxal Phosphate; Rats; Vitamin B 6 Deficiency | 1969 |
Glycine metabolism. II. Kinetic and optical studies on the glycine decarboxylase system from Peptococcus glycinophilus.
Topics: Carboxy-Lyases; Cysteine; Fluorometry; Glycine; In Vitro Techniques; Kinetics; Peptococcus; Pyridoxal Phosphate; Spectrophotometry; Ultraviolet Rays | 1966 |
Glycine metabolism. IV. Effect of borohydride reduction on the pyridoxal phosphate-containing glycine decarboxylase from Peptococcus glycinophilus.
Topics: Boron; Carboxy-Lyases; Fluorescence; Glycine; Peptococcus; Pyridoxal Phosphate; Spectrophotometry | 1967 |
Complexes of pyridoxal phosphate with amino acids, peptides, polylysine, and apotransaminase.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry; Dipeptides; Glutamates; Glycine; Hydrogen-Ion Concentration; Lysine; Peptides; Pyridoxal Phosphate; Spectrophotometry; Transaminases | 1967 |
Glycine synthesis by extracts of acetone powder of rat-liver mitochondria.
Topics: Acetone; Animals; Carbon Isotopes; Dialysis; Folic Acid; Glycine; Liver; Mitochondria; Pyridoxal Phosphate; Rats; Serine; Transferases | 1967 |
Multiwavelength analysis of the aldehyde hydration of pyridoxal phosphate: a stopped flow study.
Topics: Aldehydes; Chemical Phenomena; Chemistry; Glycine; Kinetics; Pyridoxal Phosphate; Schiff Bases | 1982 |
Microspectrophotometric measurements on single crystals of mitochondrial serine hydroxymethyltransferase.
Topics: Animals; Crystallization; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Mitochondria, Liver; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Transferases | 1981 |
Mechanism-based inactivation of pig heart L-alanine transaminase by L-propargylglycine. Half-site reactivity.
Topics: Alanine Transaminase; Alkynes; Animals; Binding Sites; Glycine; Kinetics; Macromolecular Substances; Molecular Weight; Myocardium; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Swine | 1980 |
Aminolevulinate synthase: lysine 313 is not essential for binding the pyridoxal phosphate cofactor but is essential for catalysis.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Base Sequence; Catalysis; Circular Dichroism; Glycine; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry | 1995 |
Role of the conserved glycyl residues located at the active site of leucine dehydrogenase from Bacillus stearothermophilus.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; Binding Sites; Caproates; Catalysis; Enzyme Stability; Geobacillus stearothermophilus; Glycine; Hydrolysis; Kinetics; Leucine Dehydrogenase; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Spectrometry, Fluorescence | 1994 |
Methionine biosynthesis in higher plants. I. Purification and characterization of cystathionine gamma-synthase from spinach chloroplasts.
Topics: Alkynes; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Cell Compartmentation; Chloroplasts; Cystathionine; Glycine; Homocysteine; Homoserine; Kinetics; Lyases; Methionine; Molecular Weight; Pargyline; Plant Leaves; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spinacia oleracea | 1995 |
Aminolevulinate synthase: functionally important residues at a glycine loop, a putative pyridoxal phosphate cofactor-binding site.
Topics: 5-Aminolevulinate Synthetase; Animals; Base Sequence; Binding Sites; Crystallography; DNA, Complementary; Erythrocytes; Escherichia coli; Glycine; Mice; Molecular Sequence Data; Mutagenesis; Pyridoxal Phosphate | 1995 |
Identity and some properties of the L-threonine aldolase activity manifested by pure 2-amino-3-ketobutyrate ligase of Escherichia coli.
Topics: Acetyltransferases; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Hot Temperature; Hydrogen-Ion Concentration; Iodoacetamide; Kinetics; Pyridoxal Phosphate; Substrate Specificity; Threonine | 1993 |
Determination of a functional lysine residue of a plant cysteine synthase by site-directed mutagenesis, and the molecular evolutionary implications.
Topics: Amino Acid Sequence; Base Sequence; Biological Evolution; Cysteine Synthase; Escherichia coli; Gene Expression Regulation, Enzymologic; Glycine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Plasmids; Pyridoxal Phosphate; Structure-Activity Relationship | 1993 |
Inhibition of tryptophan synthase by (1-fluorovinyl)glycine.
Topics: Acetone; Fluorides; Glycine; Kinetics; Models, Chemical; Pyridoxal Phosphate; Salmonella typhimurium; Spectrophotometry; Tryptophan Synthase | 1993 |
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria.
Topics: Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Carbohydrate Dehydrogenases; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glutarates; Glyceric Acids; Glycine; Humans; Ketoglutaric Acids; Kinetics; Models, Chemical; Oxidation-Reduction; Phosphoglycerate Dehydrogenase; Pyridoxal Phosphate; Pyruvates; Serine | 1996 |
A large compressibility change of protein induced by a single amino acid substitution.
Topics: Aspartate Aminotransferases; Aspartic Acid; Escherichia coli; Glutamic Acid; Glycine; Linear Models; NADP; Phenylalanine; Point Mutation; Proteins; Pyridoxal Phosphate; Tetrahydrofolate Dehydrogenase; Valine | 1996 |
Mutations at a glycine loop in aminolevulinate synthase affect pyridoxal phosphate cofactor binding and catalysis.
Topics: 5-Aminolevulinate Synthetase; Amino Acid Sequence; Animals; Catalysis; Circular Dichroism; Computer Simulation; Glycine; Hot Temperature; Kinetics; Mice; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Denaturation; Protein Structure, Secondary; Pyridoxal Phosphate; Structure-Activity Relationship; Ultraviolet Rays | 1996 |
Isolation and characterization of D-threonine aldolase, a pyridoxal-5'-phosphate-dependent enzyme from Arthrobacter sp. DK-38.
Topics: Acetaldehyde; Aldehyde-Lyases; Amino Acid Sequence; Amino Acids; Arthrobacter; Cations; Enzyme Stability; Glycine; Molecular Sequence Data; Molecular Weight; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity; Threonine | 1997 |
Purification and properties of serine hydroxymethyltransferase from Sulfolobus solfataricus.
Topics: Archaeal Proteins; Glycine; Glycine Hydroxymethyltransferase; Peptide Fragments; Pyridoxal Phosphate; Sequence Analysis; Sequence Homology, Amino Acid; Species Specificity; Stereoisomerism; Substrate Specificity; Sulfolobus; Threonine | 1997 |
A substrate-induced change in the stereospecificity of the serine-hydroxymethyltransferase-catalysed exchange of the alpha-protons of amino acids--evidence for a second catalytic site.
Topics: Amino Acids; Bacterial Proteins; Binding Sites; Borohydrides; Butyrates; Caproates; Carbon Isotopes; Catalysis; Deuterium; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Molecular Conformation; Pentanoic Acids; Protons; Pyridoxal Phosphate; Schiff Bases; Substrate Specificity; Tetrahydrofolates | 1998 |
Cystathionine gamma-synthase from Arabidopsis thaliana: purification and biochemical characterization of the recombinant enzyme overexpressed in Escherichia coli.
Topics: Alkynes; Amino Acid Sequence; Arabidopsis; Binding Sites; Carbon-Oxygen Lyases; Cloning, Molecular; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Homoserine; Kinetics; Lysine; Macromolecular Substances; Methionine; Molecular Sequence Data; Pyridoxal Phosphate; Recombinant Proteins | 1998 |
The pyridoxal-5'-phosphate-dependent catalytic antibody 15A9: its efficiency and stereospecificity in catalysing the exchange of the alpha-protons of glycine.
Topics: Antibodies, Catalytic; Antibody Specificity; Glycine; Protons; Pyridoxal Phosphate; Substrate Specificity | 1998 |
Inhibition of NMDA-gated ion channels by the P2 purinoceptor antagonists suramin and reactive blue 2 in mouse hippocampal neurones.
Topics: Animals; Cells, Cultured; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Ion Channels; Mice; N-Methylaspartate; Neurons, Afferent; Patch-Clamp Techniques; Protein Synthesis Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Suramin; Triazines | 1998 |
The effect of histidine-228 on the catalytic efficiency and stereospecificity of the serine hydroxymethyltransferase catalysed exchange of the alpha-protons of amino acids.
Topics: Asparagine; Coenzymes; Glycine; Glycine Hydroxymethyltransferase; Histidine; Models, Chemical; Mutation; Protons; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity | 1998 |
Catalytic mechanism of the tryptophan synthase alpha(2)beta(2) complex. Effects of pH, isotopic substitution, and allosteric ligands.
Topics: Alanine; Allosteric Regulation; Catalytic Domain; Deuterium; Glycine; Hydrogen-Ion Concentration; Indoles; Ligands; Models, Chemical; Oxindoles; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Tryptophan Synthase | 1999 |
Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.
Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Binding Sites; Crystallization; Crystallography, X-Ray; Dimerization; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Humans; Leucovorin; Models, Molecular; Molecular Sequence Data; Osmolar Concentration; Protein Structure, Quaternary; Pteroylpolyglutamic Acids; Pyridoxal Phosphate; Rabbits; Sequence Alignment; Solvents; Structure-Activity Relationship; Tetrahydrofolates | 2000 |
Transient nonketotic hyperglycinemia in an asphyxiated patient with pyridoxine-dependent seizures.
Topics: Asphyxia Neonatorum; Brain; Electroencephalography; Glycine; Humans; Hyperglycinemia, Nonketotic; Infant, Newborn; Male; Pyridoxal Phosphate; Seizures; Treatment Outcome; Vitamin B 6 Deficiency | 2000 |
Engineering acyclic stereocontrol in the alkylation of vinylglycine-derived dianions: asymmetric synthesis of higher alpha-vinyl amino acids.
Topics: Alkylation; Amino Acids; Enzyme Inhibitors; Glycine; Hydrolysis; Indicators and Reagents; Pyridoxal Phosphate; Temperature; Vinyl Compounds | 2000 |
Crystal structure of cystalysin from Treponema denticola: a pyridoxal 5'-phosphate-dependent protein acting as a haemolytic enzyme.
Topics: Binding Sites; Catalysis; Crystallography, X-Ray; Cystathionine gamma-Lyase; Glycine; Hemolysin Proteins; Hemolysis; Hydrogen Sulfide; Models, Molecular; Protein Folding; Pyridoxal Phosphate; Sulfur; Treponema | 2000 |
Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms.
Topics: Amino Acid Sequence; Catalysis; Crystallography, X-Ray; Glycine; Lyases; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate | 2001 |
Developmental changes in P2X purinoceptors on glycinergic presynaptic nerve terminals projecting to rat substantia gelatinosa neurones.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Animals; Bicuculline; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; Glycine; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Platelet Aggregation Inhibitors; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Substantia Gelatinosa | 2001 |
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; Glycine; Humans; Immunohistochemistry; Neural Inhibition; Presynaptic Terminals; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Glycine; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X4; Spinal Cord; Suramin; Synaptic Membranes; Synaptic Transmission; Zinc | 2002 |
Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation.
Topics: Alanine Racemase; Amino Acid Substitution; Benzaldehydes; Binding Sites; Fructose-Bisphosphate Aldolase; Glycine; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine | 2003 |
Enzymatic breakdown of threonine by threonine aldolase.
Topics: Acetaldehyde; Animals; Glycine; Glycine Hydroxymethyltransferase; Kinetics; Lyases; Pyridoxal Phosphate; Rats; Threonine | 1954 |
The interconversion of serine and glycine: participation of pyridoxal phosphate.
Topics: Coenzymes; Fabaceae; Glycine; Pyridoxal Phosphate; Serine | 1955 |
[ACTIVITY OF AMINOXY- AND HYDROXYLAMINO-ANALOGUES OF PHENYLALANINE AND OF GLYCINE ON SOME PYRIDOXAL PHOSPHATE-DEPENDENT ENZYMATIC REACTIONS].
Topics: Aspartate Aminotransferases; Dopa Decarboxylase; Glycine; Kidney; Liver; Metabolism; Pharmacology; Phenylalanine; Pyridoxal Phosphate; Rats; Research; Tryptophan | 1964 |
PURIFICATION AND PROPERTIES OF THREONINE OR ALLOTHREONINE ALDOLASE FROM RAT LIVER.
Topics: Acetaldehyde; Aldehyde-Lyases; Charcoal; Chromatography; Dialysis; Enterococcus faecalis; Glycine; Glycine Hydroxymethyltransferase; Hydroxylamines; Liver; Pyridoxal Phosphate; Rats; Renal Dialysis; Research; Threonine; Transferases | 1964 |
Cloning, expression, and characterization of 5-aminolevulinic acid synthase from Rhodopseudomonas palustris KUGB306.
Topics: 5-Aminolevulinate Synthetase; Acyl Coenzyme A; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Coenzymes; DNA, Bacterial; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Gene Expression; Glycine; Hydrogen-Ion Concentration; Metals; Molecular Sequence Data; Pyridoxal Phosphate; Recombinant Fusion Proteins; Rhodopseudomonas; Sequence Analysis, DNA; Spectrum Analysis; Substrate Specificity; Temperature | 2004 |
Hemoglobin polymerized with a naturally occurring crosslinking agent as a blood substitute: in vitro and in vivo studies.
Topics: Animals; Biopolymers; Blood Substitutes; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Exchange Transfusion, Whole Blood; Glycine; Hemoglobins; Iridoid Glycosides; Iridoids; Male; Methemoglobin; Molecular Structure; Pyrans; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Swine | 2004 |
Following an ISES lead: the first examples of asymmetric Ni(0)-mediated allylic amination.
Topics: Amination; Catalysis; Enzyme Inhibitors; Glycine; Nickel; Phosphines; Pyridoxal Phosphate | 2004 |
Claisen-type addition of glycine to pyridoxal in water.
Topics: Alanine; Glycine; Pyridoxal Phosphate; Water | 2004 |
Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction.
Topics: beta-Alanine; Binding Sites; Butyrates; Carbon-Carbon Lyases; Catalysis; Crystallization; Crystallography, X-Ray; Cyclopropanes; Diamines; Enzyme Inhibitors; Glycine; Mutagenesis, Site-Directed; Pichia; Pseudomonas; Pyridoxal Phosphate; Structural Homology, Protein; Substrate Specificity; Tyrosine | 2004 |
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men.
Topics: Adult; Carbon Isotopes; Deuterium; Female; Glycine; Homocysteine; Humans; Male; Methionine; Methylation; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Pyridoxal Phosphate; Serine; Vitamin B 6 | 2005 |
Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine.
Topics: Crystallography, X-Ray; Enzyme Inhibitors; Glycine; Lyases; Malus; Models, Molecular; Molecular Structure; Protein Structure, Tertiary; Pyridoxal Phosphate; Substrate Specificity | 2005 |
Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans.
Topics: 5-Aminolevulinate Synthetase; Acyl Coenzyme A; Amino Acid Sequence; Anemia, Sideroblastic; Binding Sites; Crystallography, X-Ray; Dimerization; Genetic Diseases, X-Linked; Glycine; Heme; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Protein Structure, Quaternary; Pyridoxal Phosphate; Rhodobacter capsulatus; Sequence Alignment; Substrate Specificity | 2005 |
Histidine 282 in 5-aminolevulinate synthase affects substrate binding and catalysis.
Topics: 5-Aminolevulinate Synthetase; Alanine; Animals; Catalysis; Crystallography, X-Ray; Glycine; Histidine; Kinetics; Mice; Mutagenesis, Site-Directed; Protein Binding; Pyridoxal Phosphate; Rhodobacter capsulatus; Spectrophotometry; Substrate Specificity | 2007 |
The effect of zinc on glycinergic inhibitory postsynaptic currents in rat spinal dorsal horn neurons.
Topics: 4-Aminopyridine; Action Potentials; Adenosine Triphosphate; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Drug Interactions; Glycine; Glycine Agents; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Platelet Aggregation Inhibitors; Posterior Horn Cells; Potassium Channel Blockers; Pyridoxal Phosphate; Rats; Rats, Wistar; Spinal Cord; Strychnine; Tetrodotoxin; Trace Elements; Zinc | 2007 |
Negative and positive allosteric modulators of the P2X(7) receptor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Allosteric Regulation; Animals; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Ethidium; Glycine; Humans; Molecular Structure; Piperazines; Protein Conformation; Pyridoxal Phosphate; Quinolines; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Recombinant Proteins; Species Specificity; Time Factors; Transfection; Vanadates | 2008 |
Identification of regions of the P2X(7) receptor that contribute to human and rat species differences in antagonist effects.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Glycine; Humans; Imidazoles; Molecular Sequence Data; Mutagenesis, Site-Directed; Piperazines; Plasmids; Polymorphism, Single Nucleotide; Protein Binding; Protein Structure, Tertiary; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridines; Pyridoxal Phosphate; Radioligand Assay; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Sequence Alignment; Species Specificity; Transfection | 2008 |
Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Geobacillus stearothermophilus; Glycine; Glycine Hydroxymethyltransferase; Models, Molecular; Protein Binding; Pyridoxal Phosphate; Serine; Stereoisomerism; Tetrahydrofolates; Threonine; Tyrosine | 2008 |
Synthesis of beta-hydroxy-alpha-amino acids with a reengineered alanine racemase.
Topics: Alanine; Alanine Racemase; Aldehydes; Amino Acids; Bacteria; Catalysis; Combinatorial Chemistry Techniques; Glycine; Glycine Hydroxymethyltransferase; Molecular Structure; Protein Engineering; Pyridoxal Phosphate; Stereoisomerism | 2008 |
Substituent effects on the thermodynamic stability of imines formed from glycine and aromatic aldehydes: implications for the catalytic activity of pyridoxal-5'-phosphate.
Topics: Benzaldehydes; Catalysis; Glycine; Hydrogen Bonding; Imines; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Static Electricity; Thermodynamics | 2009 |
L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Topics: Alkynes; Analysis of Variance; Animals; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Glycine; Hydrogen Sulfide; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2010 |
An insight into the sequential, structural and phylogenetic properties of banana 1-aminocyclopropane-1-carboxylate synthase 1 and study of its interaction with pyridoxal-5'-phosphate and aminoethoxyvinylglycine.
Topics: Amino Acid Sequence; Animals; Ethylenes; Glycine; Lyases; Molecular Sequence Data; Musa; Phylogeny; Plant Proteins; Protein Conformation; Pyridoxal Phosphate; Tissue Distribution | 2010 |
Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase.
Topics: Bacterial Proteins; Biocatalysis; Carbon Isotopes; Carbon-Sulfur Lyases; Citrobacter freundii; Glycine; Kinetics; Proteus vulgaris; Protons; Pyridoxal Phosphate; Stereoisomerism; Tryptophanase; Tyrosine Phenol-Lyase | 2011 |
Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Dioxanes; gamma-Aminobutyric Acid; Glycine; Indoles; Inhibitory Postsynaptic Potentials; Male; Mecamylamine; Melitten; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Antagonists; Norepinephrine; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Serotonin Antagonists; Substantia Gelatinosa; Synaptic Transmission; Tropisetron | 2011 |
Increase or decrease hydrogen sulfide exert opposite lipolysis, but reduce global insulin resistance in high fatty diet induced obese mice.
Topics: Adipocytes; Alkynes; Animals; Blood Glucose; Carrier Proteins; Cystathionine gamma-Lyase; Cysteine; Diet, High-Fat; Enzyme Inhibitors; Glycerol; Glycine; Hydrogen Sulfide; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Mice; Morpholines; Obesity; Organothiophosphorus Compounds; Perilipin-1; Phosphoproteins; Primary Cell Culture; Pyridoxal Phosphate; Rats; Sterol Esterase | 2013 |
Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors.
Topics: Alanine; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Citrobacter freundii; Crystallography, X-Ray; Cycloserine; Cysteine; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Imines; Kinetics; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins; Thermodynamics; Valine | 2015 |
The crystal structure of D-threonine aldolase from Alcaligenes xylosoxidans provides insight into a metal ion assisted PLP-dependent mechanism.
Topics: Acetaldehyde; Alanine Racemase; Alcaligenes; Aldehyde-Lyases; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Escherichia coli; Glycine; Manganese; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Multigene Family; Protein Conformation; Protein Structure, Tertiary; Protons; Pyridoxal Phosphate; Recombinant Proteins; Serine; Structure-Activity Relationship; Threonine | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Cloning and characterization of d-threonine aldolase from the green alga Chlamydomonas reinhardtii.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Chlamydomonas reinhardtii; Cloning, Molecular; Escherichia coli; Glycine; Glycine Hydroxymethyltransferase; Pyridoxal Phosphate; Stereoisomerism; Substrate Specificity; Threonine | 2017 |
Vitamin B6 is essential for serine de novo biosynthesis.
Topics: Brain; Cells, Cultured; Glycine; Humans; Pyridoxal Phosphate; Pyridoxine; Serine; Vitamin B 6; Vitamin B 6 Deficiency | 2017 |
Identification of O-acetylhomoserine sulfhydrylase, a putative enzyme responsible for methionine biosynthesis in Clostridioides difficile: Gene cloning and biochemical characterizations.
Topics: Alkynes; Amino Acid Sequence; Carbon-Oxygen Lyases; Cloning, Molecular; Clostridioides difficile; Genome, Bacterial; Glycine; Methionine; Pyridoxal Phosphate; Sequence Homology; Substrate Specificity; Sulfhydryl Compounds | 2019 |
Proteomic, Transcriptomic, Mutational, and Functional Assays Reveal the Involvement of Both THF and PLP Sites at the GmSHMT08 in Resistance to Soybean Cyst Nematode.
Topics: Animals; Carbon; Cysts; Glycine; Glycine Hydroxymethyltransferase; Glycine max; Glyoxylates; Heme; Methionine; Nematoda; Plant Diseases; Proteomics; Purines; Pyridoxal Phosphate; Serine; Tetrahydrofolates; Transcriptome | 2022 |