pyridoxal phosphate and glutaminase

pyridoxal phosphate has been researched along with glutaminase in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's0 (0.00)18.2507
2000's11 (55.00)29.6817
2010's4 (20.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Chung, SH; Gabrielsson, B; Norris, DK1
Berezov, TT1
Göllnitz, G; Wiechert, P1
Bauer, JA; Begley, TP; Bennett, EM; Ealick, SE1
Begley, TP; Burns, KE; Kinsland, CL; McLafferty, FW; Xiang, Y1
Belitsky, BR; Burgner, JW; Harms, E; Smith, JL; Zhu, J1
Amrhein, N; Fitzpatrick, TB; Raschle, T1
Fitzpatrick, TB; Mazurkiewicz, J; Raschle, T; Rippe, K; Sinning, I; Strohmeier, M; Tews, I1
Amrhein, N; Fitzpatrick, TB; Tambasco-Studart, M; Tews, I1
Begley, TP; Burns, KE; Chatterjee, A; Dorrestein, PC; Hanes, JW; Hilmey, DG1
Begley, TP; Hanes, JW; Keresztes, I1
Townsend, C1
Amrhein, N; Fitzpatrick, TB; Gehrig, P; Kress, W; Moccand, C; Raschle, T; Speziga, D; Weber-Ban, E1
Flicker, K; Macheroux, P; Neuwirth, M; Tews, I; Wallner, S1
Derrer, B; Gengenbacher, M; Guédez Rodríguez, G; Kappes, B; Lehmann, WD; Rippe, K; Seidler, J; Sinning, I; Tews, I; Windeisen, V1
Fitzpatrick, TB; Kaufmann, M; Moccand, C1
Böttcher, B; Derrer, B; Gengenbacher, M; Guédez, G; Hipp, K; Kappes, B; Sinning, I; Tews, I; Windeisen, V1
Brown, WC; Harms, E; Smith, AM; Smith, JL1
Andaleeb, H; Betzel, C; Falke, S; Mudogo, CN; Ullah, N; Wrenger, C1
Cerqueira, NMFSA; Pina, AF; Sousa, SF1

Reviews

2 review(s) available for pyridoxal phosphate and glutaminase

ArticleYear
Transition metal ions in epilepsy: an overview.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Amino Acids; Animals; Biological Transport; Cations, Divalent; Enzymes; Epilepsy; Extracellular Space; Glutamate Decarboxylase; Glutamate Dehydrogenase; Glutaminase; Humans; Metals; Neurotransmitter Agents; Pyridoxal Phosphate; Receptors, Neurotransmitter; Synaptic Transmission

1986
[Enzyme therapy of neoplasms].
    Vestnik Akademii meditsinskikh nauk SSSR, 1971, Volume: 26, Issue:11

    Topics: Animals; Arginase; Asparaginase; Carcinoma 256, Walker; Carcinoma, Brown-Pearce; Carcinoma, Ehrlich Tumor; Carcinoma, Krebs 2; Chymotrypsin; Deoxyribonucleases; Enzyme Therapy; Glutaminase; Hyaluronoglucosaminidase; Leukemia, Experimental; Leukemia, Radiation-Induced; Lyases; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Pyridoxal Phosphate; Rats; Ribonucleases; Salts; Sarcoma, Avian; Sarcoma, Experimental; Trypsin; Vanadium

1971

Other Studies

18 other study(ies) available for pyridoxal phosphate and glutaminase

ArticleYear
[Metabolic studies on epileptic seizures. The activity of glutaminase and glutamine synthetase and ammonia metabolism before and during cerebral convulsions].
    Journal of neurochemistry, 1969, Volume: 16, Issue:3

    Topics: Ammonia; Animals; Brain; Glutaminase; Ligases; Pyridoxal Phosphate; Rats; Seizures

1969
Three-dimensional structure of YaaE from Bacillus subtilis, a glutaminase implicated in pyridoxal-5'-phosphate biosynthesis.
    The Journal of biological chemistry, 2004, Jan-23, Volume: 279, Issue:4

    Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Binding Sites; Glutaminase; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship

2004
Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway.
    Journal of the American Chemical Society, 2005, Mar-23, Volume: 127, Issue:11

    Topics: Anthranilate Synthase; Bacillus subtilis; Bacterial Proteins; Fourier Analysis; Glutaminase; Nitrogenous Group Transferases; Pyridoxal Phosphate; Spectrometry, Mass, Electrospray Ionization

2005
A new arrangement of (beta/alpha)8 barrels in the synthase subunit of PLP synthase.
    The Journal of biological chemistry, 2005, Jul-29, Volume: 280, Issue:30

    Topics: Ammonia; Bacillus subtilis; Base Sequence; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Glutaminase; Glutamine; Glycols; Models, Chemical; Models, Molecular; Models, Statistical; Molecular Sequence Data; Nitrogenous Group Transferases; Phosphorylation; Plasmids; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Ribulosephosphates; Substrate Specificity

2005
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.
    The Journal of biological chemistry, 2005, Sep-16, Volume: 280, Issue:37

    Topics: Antioxidants; Bacillus subtilis; Binding Sites; Carbon-Nitrogen Lyases; Chromatography; Chromatography, Gel; Chromatography, High Pressure Liquid; Cloning, Molecular; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glutaminase; Glutamine; Immunochemistry; Isoxazoles; Kinetics; Mass Spectrometry; Models, Chemical; Organophosphates; Oxidoreductases; Pentosephosphates; Protein Structure, Tertiary; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Threonine; Time Factors; Ultraviolet Rays; Vitamin B 6

2005
Structure of a bacterial pyridoxal 5'-phosphate synthase complex.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-19, Volume: 103, Issue:51

    Topics: Bacillus subtilis; Glutaminase; Glutamine; Models, Molecular; Multiprotein Complexes; Mutagenesis; Pyridoxal Phosphate

2006
Functional analysis of PDX2 from Arabidopsis, a glutaminase involved in vitamin B6 biosynthesis.
    Plant physiology, 2007, Volume: 144, Issue:2

    Topics: Arabidopsis; Arabidopsis Proteins; Carbon-Nitrogen Lyases; Glutaminase; Nitrogenous Group Transferases; Protein Structure, Quaternary; Pyridoxal Phosphate

2007
Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate.
    Journal of the American Chemical Society, 2008, Mar-12, Volume: 130, Issue:10

    Topics: Escherichia coli; Glutaminase; Glutamine; Pyridoxal Phosphate; Ribosemonophosphates

2008
13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase.
    Nature chemical biology, 2008, Volume: 4, Issue:7

    Topics: Bacillus subtilis; Carbon Isotopes; Catalysis; Glutaminase; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Pyridoxal Phosphate; Ribosemonophosphates; Substrate Specificity; Vitamin B 6

2008
Peering inside the black box to find enzyme-bound intermediates.
    Nature chemical biology, 2008, Volume: 4, Issue:7

    Topics: Catalysis; Glutaminase; Nuclear Magnetic Resonance, Biomolecular; Pyridoxal Phosphate; Ribosemonophosphates; Vitamin B 6

2008
Intersubunit cross-talk in pyridoxal 5'-phosphate synthase, coordinated by the C terminus of the synthase subunit.
    The Journal of biological chemistry, 2009, Mar-20, Volume: 284, Issue:12

    Topics: Bacillus subtilis; Bacterial Proteins; Catalytic Domain; Glutaminase; Glyceraldehyde 3-Phosphate; Ligases; Multienzyme Complexes; Protein Binding; Pyridoxal Phosphate; Ribosemonophosphates; Spectrometry, Fluorescence; Thermotoga maritima; Transaminases; Xylose

2009
Dissection of contributions from invariant amino acids to complex formation and catalysis in the heteromeric pyridoxal 5-phosphate synthase complex from Bacillus subtilis.
    Biochemistry, 2009, Mar-10, Volume: 48, Issue:9

    Topics: Bacillus subtilis; Bacterial Proteins; Catalysis; Glutaminase; Kinetics; Models, Chemical; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Mutant Proteins; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Pyridoxal Phosphate; Substrate Specificity

2009
Defining the structural requirements for ribose 5-phosphate-binding and intersubunit cross-talk of the malarial pyridoxal 5-phosphate synthase.
    FEBS letters, 2010, Oct-08, Volume: 584, Issue:19

    Topics: Amino Acid Sequence; Animals; Base Sequence; DNA, Protozoan; Glutaminase; Kinetics; Models, Molecular; Molecular Sequence Data; Multiprotein Complexes; Plasmodium falciparum; Protein Subunits; Protozoan Proteins; Pyridoxal Phosphate; Recombinant Proteins; Ribosemonophosphates; Sequence Deletion

2010
It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase.
    PloS one, 2011, Jan-21, Volume: 6, Issue:1

    Topics: Animals; Catalytic Domain; Glutaminase; Glyceraldehyde 3-Phosphate; Humans; Metabolic Networks and Pathways; Multienzyme Complexes; Protein Binding; Pyridoxal Phosphate; Ribosemonophosphates; Transaminases; Vitamin B 6

2011
Assembly of the eukaryotic PLP-synthase complex from Plasmodium and activation of the Pdx1 enzyme.
    Structure (London, England : 1993), 2012, Jan-11, Volume: 20, Issue:1

    Topics: Ammonia; Catalytic Domain; Crystallography; Enzyme Activation; Glutaminase; Methionine; Models, Molecular; Multiprotein Complexes; Plasmodium falciparum; Protein Conformation; Pyridoxal Phosphate

2012
Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.
    The Journal of biological chemistry, 2015, Feb-27, Volume: 290, Issue:9

    Topics: Ammonia; Aspartic Acid; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Catalytic Domain; Crystallography, X-Ray; Geobacillus stearothermophilus; Glutaminase; Glutamine; Glyceraldehyde 3-Phosphate; Kinetics; Lysine; Models, Molecular; Molecular Structure; Mutation; Protein Conformation; Pyridoxal Phosphate; Ribosemonophosphates; Spectrometry, Mass, Electrospray Ionization

2015
Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1-Pdx2 Complex.
    International journal of molecular sciences, 2020, Aug-19, Volume: 21, Issue:17

    Topics: Binding Sites; Glutaminase; Molecular Dynamics Simulation; Plasmodium vivax; Protein Binding; Protein Multimerization; Protozoan Proteins; Pyridoxal Phosphate; Vitamin B 6

2020
The Catalytic Mechanism of Pdx2 Glutaminase Driven by a Cys-His-Glu Triad: A Computational Study.
    Chembiochem : a European journal of chemical biology, 2022, 05-04, Volume: 23, Issue:9

    Topics: Catalysis; Glutamic Acid; Glutaminase; Glutamine; Humans; Malaria; Pyridoxal Phosphate

2022