pyridoxal phosphate and gamma-aminobutyric acid

pyridoxal phosphate has been researched along with gamma-aminobutyric acid in 116 studies

Research

Studies (116)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (46.55)	18.7374
1990's	15 (12.93)	18.2507
2000's	20 (17.24)	29.6817
2010's	22 (18.97)	24.3611
2020's	5 (4.31)	2.80

Authors

Authors	Studies
Martin, DL; Mazumder, A; Miller, LP; Walters, JR	1
Horton, R; Meldrum, B; Sawaya, C	1
Hsiao, WL; Krooth, RS; Lam, GF	1
Barker, HA; Bozler, G; Hensley, C; Ohsugi, M; Robertson, JM	1
Horton, RW; Meldrum, BS; Sawaya, MC	1
Sarhan, S; Seiler, N	1
Beart, PM; Bilal, K	1
Ebadi, M; Govitrapong, P	1
Ebadi, M; Klangkalya, B	1
Tunnicliff, G	2
Charington, CB; Tsui, D; Wood, JD	1
White, HL	1
Chapman, AG; Horton, RW; Meldrum, BS	1
Jung, MJ; Metcalf, BW	1
Martin, DL; Martin, SB	1
Coulombe, T; Di Paolo, RV; Levy, HL; Lott, IT; Richardson, EP	1
Brockman, DE; Martin, DL; Miller, LP; Seligmann, B	1
Korhonen, K; Lähdesmäki, P	1
Eto, K; Hoshino, M; Matsuda, M; Sakurai, T; Takahashi, Y	1
Pearce, MJ; Taberner, PV; Watkins, JC	1
Bayón, A; Possani, LD; Tapia, R	1
Contreras, P; Sandoval, ME; Tapia, R	1
Sandoval, ME; Tapia, R	1
Ghoneim, MT; Mahfouz, M; Makar, AB; Mikhail, MM	1
Arce, C; Cañadas, S; De Vicente, M; González, MP; Oset-Gasque, MJ	1
Erlander, MG; Greif, KF; Tillakaratne, NJ; Tobin, AJ	1
Cassel, G; Karlsson, L; Sellström, A	1
Houser, CR; Kaufman, DL; Tobin, AJ	1
DeFeudis, FV	1
Ebadi, M; Murrin, LC; Pfeiffer, RF	1
Foulks, JG; Godolphin, WJ; Ito, M; Kish, SJ; Perry, TL; Sweeney, VP; Yong, VW	1
Tunnicliff, G; Youngs, TL	1
Martin, DL; Porter, TG	2
Turský, T	1
Martin, DL	1
Dakshinamurti, K; Packer, S; Paulose, CS; Stephens, NL	1
Green, AR; Vincent, ND	1
David, S; Kalyankar, GD	1
Davies, WE; Fisher, SK	1
Hansen, S; Kennedy, J; Perry, TL; Urquhart, N	1
Simmonds, MA; Sutton, I	1
Casti, A; Clo, C; Fussi, F	1
Tyce, GM; Wong, KL	1
Dakshinamurti, K	1
Geddes, JW; Wood, JD	1
Regunathan, S; Sundaresan, R	1
Erdö, SL; Kiss, B; Szporny, L	1
Kryzhanovskiĭ, GN; Nikushkin, EV; Shandra, AA	1
Deupree, JD; Ebadi, M; Klangkalya, B	1
Ebadi, M; Mebus, C; Ramaley, R; Swanson, S; Wilt, S	1
Kryzhanovskiĭ, GN; Shandra, AA	1
Baxter, CF; Grossfeld, RM; Yancey, SW	1
Christenson, WR; Ebadi, M; Metzler, DE	1
Dakshinamurti, K; Paulose, CS	1
Ebadi, M; Kouyoumdjian, JC	1
Coburn, SP; Guilarte, TR; Jaje, JM; MacGregor, GR; Mahuren, JD; Waymire, KG	1
Hopkins, MH; Lightcap, ES; Olson, GT; Silverman, RB	1
Luby, V; Miller, T; Omar, SJ; Robinson, D; Tinklenberg, J	1
Baumeister, FA; Egger, J; Gsell, W; Shin, YS	1
Massieu, L; Rivera, A; Tapia, R	1
Erecińska, M; Michalik, M; Nelson, J	1
De Biase, D; Pascarella, S; Toney, MD	1
Cunningham, JR; Dent, Z; Neal, MJ	1
Crites, GJ; Tunnicliff, G	1
Boesiger, P; Mueller, SG; Weber, OM; Wieser, HG	1
Salazar, P; Tapia, R	1
Chin, J; Fayad, K; Law, RH; Mackay, IR; Rowley, MJ; Tong, JC	1
Baxter, P	1
WALLACH, DP	1
CARTER, CE; DANN, OT	1
O'BRIEN, RD; UCHIDA, T	1
Bossa, F; Bruno, S; De Biase, D; Mozzarelli, A; Peneff, C; Schirmer, T; Silverman, RB; Storici, P	1
Gibson, KM; Pearl, PL	1
Kamiyama, N; Miyamoto, Y; Murakami, H; Sasamoto, Y; Yamamoto, H	1
Belitsky, BR	1
Papp, L; Sperlágh, B; Vizi, ES	1
Cho, JH; Choi, SY; Hwang, IK; Jung, JY; Kang, TC; Kim, DW; Kim, YS; Kwon, OS; Won, MH; Yoo, KY	1
Reis, HJ; Romano-Silva, MA; Smith, TK; Vanden Berghe, P	1
Barajas-López, C; Espinosa-Luna, R; García-Hernández, LM; Karanjia, R; Miranda-Morales, M; Montaño, LM; Somani, N	1
Lalo, U; North, RA; Pankratov, Y; Verkhratsky, A	1
Bie, XM; Jiao, Y; Lü, FX; Lu, ZX; Sun, LJ; Yang, SY; Yu, B	1
Hwang, IK; Kim, DH; Kwon, YG; Lee, BH; Won, MH; Yoo, KY	1
Choi, SY; Choi, UK; Kang, JH; Kang, TC; Kim, DW; Kim, HT; Kim, JE; Kwak, SE; Kwon, OS; Lee, SJ	1
Cunha, RA; Donato, R; Edwards, FA; Miyagi, K; Rodrigues, RJ; Soto, D; Takahashi, M; Tsai, MC; Villafuertes, RG	1
Begley, TP; Hilmey, DG; Mukherjee, T	1
Davies, DL; Li, K; Xiao, C; Ye, JH; Zhou, C	1
Hosoya, T; Ishii, T; Kaneda, M	1
Lv, YG; Wang, L; Xu, DX; Zhang, H	1
Deniz, S; Erdelyi, F; Mura, C; Picaud, S; Rendon, A; Roux, MJ; Sahel, JA; Schwab, Y; Szabó, G; Wersinger, E	1
Fujita, T; Kumamoto, E; Liu, T	1
Rubí, B	1
Gökcan, H; Konuklar, FA	1
Chang, WN; Du, HC; Fu, TF; Hsiao, TH; Kao, TT; Lee, GH; Safo, MK; Sung, SY	1
Hatada, K; Kondo, A; Nakayama, H; Ogino, C; Okai, N; Shirakawa, J; Takahashi, C; Tateno, T; Tsuchidate, T	1
Li, B; Sun, H; Wang, C; Zhu, R	1
Bach, A; Belitsky, BR; Edayathumangalam, R; Garcia, R; Hoang, QQ; Kreinbring, CA; Liao, J; Liu, D; Petsko, GA; Ringe, D; Stone, TA; Terwilliger, TC; Wang, W; Wang, Y; Wu, R	1
Jeong, SJ; Kim, JH; Park, JY	1
Fukada, H; Goto, M; Hemmi, H; Ito, T; Kato, S; Kawase, Y; Kawashima, S; Okuda, K; Shiraki, S; Yoshimura, T	1
Deng, Y; Guo, Y; Han, X; Jiang, YJ; Li, L; Li, T; Man, CX; Shan, Y; Zhang, LW	1
Goto, M; Hemmi, H; Ito, T; Okuda, K; Takenaka, T; Yoshimura, T	1
Ishikawa, M; Johno, A; Kobayashi, D; Sasaki, K; Wada, K; Yoshimura, T	1
Gökcan, H; Monard, G; Sungur Konuklar, FA	1
Amidani, D; Bettati, S; Campanini, B; Canosa, AV; Contestabile, R; di Salvo, ML; Maggi, S; Milano, T; Pascarella, S; Rivetti, C; Tramonti, A	1
Averina, OV; Danilenko, VN; Dyachkova, MS; Klimina, KM; Kovtun, AS; Orlova, VS; Poluektova, EU; Yunes, RA	1
Fonta, C; Salles, JP	1
Albersen, M; Gohla, A; Hommers, L; Jeanclos, E; Lesch, KP; Raab, A; Ramos, RJJ; Verhoeven-Duif, NM; Wilhelm, C	1
Hong, J; Kim, KJ	1
Chen, F; Jannoey, P; Jiamyangyuen, S; Pramai, P; Thanasukarn, P; Thongsook, T	1
Frezzini, M; Guidoni, L; Pascarella, S	1
Butrin, A; Catlin, DS; Doubleday, PF; Kelleher, NL; Liu, D; Shen, S; Silverman, RB; Wawrzak, Z; Weerawarna, PM; Zhu, W	1
Dong, ZX; Jia, YY; Jiao, ZJ; Kan, YC; Li, X; Shi, HL; Tang, CD; Wang, LF; Xu, JH; Yao, LG	1
Chen, Q; Ma, J; Yu, P; Zhang, Q; Zhu, P	1
Ahn, J; Bhatia, SK; Choi, KY; Choi, YK; Gurav, R; Ham, S; Jeon, JM; Kim, HT; Yang, YH; Yoon, JJ	1
Beaupre, BA; Butrin, A; Doubleday, PF; Ferreira, GM; Habeeb Mohammad, TS; Kelleher, NL; Liu, D; Melani, RD; Moran, GR; Silverman, RB; Tavares, MT; Zhu, W	1

Reviews

7 review(s) available for pyridoxal phosphate and gamma-aminobutyric acid

Article	Year
Overview--GABAA receptors. Annals of the New York Academy of Sciences, 1990, Volume: 585 Topics: Animals; Barbiturates; Bicuculline; gamma-Aminobutyric Acid; Insecticides; Pyridoxal Phosphate; Receptors, GABA-A; Steroids	1990
Hippocampal zinc thionein and pyridoxal phosphate modulate synaptic functions. Annals of the New York Academy of Sciences, 1990, Volume: 585 Topics: Animals; Brain; Enzyme Activation; gamma-Aminobutyric Acid; Hippocampus; Metallothionein; Pyridoxal Kinase; Pyridoxal Phosphate; Seizures; Synapses; Zinc	1990
Regulatory properties of brain glutamate decarboxylase. Cellular and molecular neurobiology, 1987, Volume: 7, Issue:3 Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Neurons; Protein Conformation; Pyridoxal Phosphate	1987
Neurobiology of Pyridoxine. Advances in nutritional research, 1982, Volume: 4 Topics: Animals; Brain; Carboxy-Lyases; Cats; Crustacea; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Mice; Myelin Sheath; Nervous System; Neurotransmitter Agents; Ornithine Decarboxylase; Pituitary Hormones; Polyamines; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Rats; Retina; Taurine; Vitamin B 6 Deficiency	1982
Evidence for feedback regulation of glutamate decarboxylase by gamma-aminobutyric acid. Journal of neurochemistry, 1984, Volume: 43, Issue:5 Topics: Adenosine Triphosphate; Animals; Apoenzymes; Binding, Competitive; Brain; Enzyme Activation; Feedback; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Kinetics; Pyridoxal Phosphate; Synapses	1984
Pyridoxine-dependent seizures: a clinical and biochemical conundrum. Biochimica et biophysica acta, 2003, Apr-11, Volume: 1647, Issue:1-2 Topics: Drug Overdose; gamma-Aminobutyric Acid; Humans; Pyridoxal Phosphate; Pyridoxine; Seizures	2003
Clinical aspects of the disorders of GABA metabolism in children. Current opinion in neurology, 2004, Volume: 17, Issue:2 Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Brain; Carnosine; Child; Developmental Disabilities; Diagnosis, Differential; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Magnetic Resonance Imaging; Phenotype; Pyridoxal Phosphate; Pyridoxine; Succinate-Semialdehyde Dehydrogenase	2004

Trials

1 trial(s) available for pyridoxal phosphate and gamma-aminobutyric acid

Article	Year
Influence of pyridoxal 5'-phosphate alone and in combination with vigabatrin on brain GABA measured by 1H-NMR-spectroscopy. Brain research bulletin, 2001, Jul-01, Volume: 55, Issue:4 Topics: Adult; Anticonvulsants; Brain Chemistry; Creatine; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Pyridoxal Phosphate; Vigabatrin	2001

Other Studies

108 other study(ies) available for pyridoxal phosphate and gamma-aminobutyric acid

Article	Year
Studies on the regulation of GABA synthesis: substrate-promoted dissociation of pyridoxal-5'-phosphate from GAD. Journal of neurochemistry, 1978, Volume: 30, Issue:2 Topics: Aminobutyrates; Animals; Brain; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Models, Biological; Pyridoxal Phosphate; Rats	1978
Transmitter synthesis and convulsant drugs: effects of pyridoxal phosphate antagonists and allylglycine. Biochemical pharmacology, 1978, Feb-15, Volume: 27, Issue:4 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; In Vitro Techniques; Mice; Mice, Inbred DBA; Neurotransmitter Agents; Pyridoxal Phosphate	1978
Effect of 6-azauracil, and of certain structurally similar compounds, on three pyridoxal-phosphate requiring enzymes involved in neurotransmitter metabolism. Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7 Topics: 4-Aminobutyrate Transaminase; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Pyridoxal Phosphate; Rats; Uracil	1979
Metabolism of L-beta-lysine in a Pseudomonas: conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by different transaminases. Archives of biochemistry and biophysics, 1979, Oct-01, Volume: 197, Issue:1 Topics: Aminocaproates; Aminocaproic Acid; Enzyme Induction; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Substrate Specificity; Transaminases	1979
The convulsant action of methyldithiocarbazinate: a comparison with other sulphur-containing hydrazides. Journal of neurochemistry, 1975, Volume: 24, Issue:5 Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Convulsants; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hydrazines; Kinetics; Male; Mice; Phosphotransferases; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Sulfides; Thiocarbamates; Thiosemicarbazones; Transaminases	1975
Metabolic inhibitors and subcellular distribution of GABA. Journal of neuroscience research, 1979, Volume: 4, Issue:5-6 Topics: 3-Mercaptopropionic Acid; Aminocaproates; Animals; Anticonvulsants; Aromatic-L-Amino-Acid Decarboxylases; Aspartic Acid; Centrifugation, Density Gradient; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Male; Mice; Pyridoxal Phosphate; Synaptosomes; Valproic Acid	1979
Allylglycine: intranigral effects and reappraisal of actions on the GABA system. Biochemical pharmacology, 1979, Volume: 28, Issue:4 Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Brain; Convulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine; Kinetics; Male; Neurotoxins; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Substantia Nigra	1979
Biogenic amine-mediated alteration of pyridoxal phosphate formation in rat brain. Journal of neurochemistry, 1979, Volume: 32, Issue:3 Topics: Animals; Biogenic Amines; Brain; Dopamine; gamma-Aminobutyric Acid; Histamine; Male; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Serotonin; Tyramine	1979
On the mechanism of pyridoxal phosphate-related convulsions as implicated in enhanced transport of GABA. Neuropharmacology, 1979, Volume: 18, Issue:3 Topics: Animals; Antimetabolites; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Synaptosomes	1979
Inhibition by pyridoxal-5'-phosphate of gamma-aminobutyric acid receptor binding to synaptic membranes of cat cerebellum. Biochemical and biophysical research communications, 1979, Apr-13, Volume: 87, Issue:3 Topics: Animals; Cats; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Male; Pyridoxal Phosphate; Receptors, Drug; Structure-Activity Relationship; Synaptic Membranes	1979
Alteration of GABA metabolism in mammalian brain by l-alpha-amino-beta-chloropropionic acid hydroxamide and related compounds. European journal of pharmacology, 1979, May-01, Volume: 55, Issue:3 Topics: 4-Aminobutyrate Transaminase; Alanine; Animals; Anticonvulsants; Brain; gamma-Aminobutyric Acid; Male; Mice; Pyridoxal Phosphate; Time Factors	1979
4-aminobutyrate:2-oxoglutarate aminotransferase in blood platelets. Science (New York, N.Y.), 1979, Aug-17, Volume: 205, Issue:4407 Topics: 4-Aminobutyrate Transaminase; Animals; Blood Platelets; Brain; Dogs; Enzyme Activation; gamma-Aminobutyric Acid; Humans; Kinetics; Pyridoxal Phosphate; Rats; Substrate Specificity; Transaminases	1979
The convulsant action of hydrazides and regional changes in cerebral gamma-aminobutyric acid and pyridoxal phosphate concentrations. Journal of neurochemistry, 1979, Volume: 33, Issue:3 Topics: Animals; Brain; Convulsants; Female; gamma-Aminobutyric Acid; Hydrazines; Isoniazid; Pyridoxal Phosphate; Rats; Tissue Distribution	1979
Molecular basis for the irreversible inhibition of 4-aminobutyric acid:2-oxoglutarate and L-ornithine:2-oxoacid aminotransferases by 3-amino-1,5-cyclohexadienyl carboxylic acid (isogabaculline). Molecular pharmacology, 1979, Volume: 16, Issue:2 Topics: 4-Aminobutyrate Transaminase; Animals; Cyclohexanecarboxylic Acids; Cyclohexylamines; Enzyme Activation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Mice; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Temperature; Time Factors; Transaminases	1979
Stimulation by phosphate on the activation of glutamate apodecarboxylase by pyridoxyl-5'-phosphate and its implications for the control of GABA synthesis. Journal of neurochemistry, 1979, Volume: 33, Issue:6 Topics: Animals; Apoenzymes; Apoproteins; Brain; Carboxy-Lyases; Enzyme Activation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Phosphates; Pyridoxal Phosphate; Rats; Structure-Activity Relationship; Vitamin B 6 Deficiency	1979
Vitamin B6-dependent seizures: pathology and chemical findings in brain. Neurology, 1978, Volume: 28, Issue:1 Topics: Adolescent; Adult; Amino Acids; Brain; Cerebellar Cortex; Cerebral Cortex; Child; Child, Preschool; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Humans; Male; Pyridoxal Phosphate; Pyridoxine	1978
Studies on the regulation of GABA synthesis: the interaction of adenine nucleotides and glutamate with brain glutamate decarboxylase. Journal of neurochemistry, 1978, Volume: 30, Issue:2 Topics: Adenine Nucleotides; Aminobutyrates; Animals; Brain; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; In Vitro Techniques; Kinetics; Male; Pyridoxal Phosphate; Rats	1978
Comparative studies on the degradation of GABA and taurine in the brain. Journal of neurochemistry, 1978, Volume: 30, Issue:4 Topics: Aminobutyrates; Animals; Brain; Cattle; gamma-Aminobutyric Acid; In Vitro Techniques; Isethionic Acid; Mice; Mitochondria; Pyridoxal Phosphate; Rats; Succinates; Synaptosomes; Taurine; Tissue Distribution	1978
Effect of pyridoxal administration on the contents of pyridoxal phosphate and gamma-aminobutyric acid in mouse brain. Journal of nutritional science and vitaminology, 1978, Volume: 24, Issue:3 Topics: Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Pyridoxal; Pyridoxal Phosphate; Subcellular Fractions	1978
The inhibition of mouse brain glutamate decarboxylase by some structural analogues of L-glutamic acid. Biochemical pharmacology, 1977, Feb-15, Volume: 26, Issue:4 Topics: Animals; Brain; Carboxy-Lyases; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; In Vitro Techniques; Kinetics; Male; Mice; Pyridoxal Phosphate; Spectrophotometry; Transaminases	1977
Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids. Journal of neurochemistry, 1977, Volume: 29, Issue:3 Topics: Amino Acids; Aminooxyacetic Acid; Animals; Brain; Carboxy-Lyases; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Mice; Pyridoxal Phosphate	1977
Evidence for a role of glutamate decarboxylase activity as a regulatory mechanism of cerebral excitability. Journal of neurochemistry, 1975, Volume: 24, Issue:6 Topics: Aminobutyrates; Animals; Azides; Brain; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Mice; Pyridoxal Phosphate; Seizures; Time Factors	1975
GABA metabolism and cerebral protein synthesis. Brain research, 1975, Oct-17, Volume: 96, Issue:2 Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hydrazines; In Vitro Techniques; Leucine; Mice; Nerve Tissue Proteins; Oximes; Pyridoxal Phosphate	1975
Effect of hashish on brain gamma aminobutyric acid system, blood fibrinolytic activity and glucose and some serum enzymes in the rat. Die Pharmazie, 1975, Volume: 30, Issue:12 Topics: 4-Aminobutyrate Transaminase; Alanine Transaminase; Amino Acids; Animals; Aspartate Aminotransferases; Blood Glucose; Brain; Cannabis; Fibrinolysis; gamma-Aminobutyric Acid; Glutamate Decarboxylase; L-Lactate Dehydrogenase; Male; Pyridoxal Phosphate; Rats	1975
Comparative study between 4-aminobutyrate-2-oxoglutarate aminotransferase (GABA-T) from rat forebrain and cerebellum. Neurochemical research, 1992, Volume: 17, Issue:7 Topics: 4-Aminobutyrate Transaminase; Aminooxyacetic Acid; Animals; Aspartic Acid; Brain Chemistry; Cerebellum; gamma-Aminobutyric Acid; Prosencephalon; Pyridoxal Phosphate; Rats; Rats, Wistar	1992
Postnatal expression of glutamate decarboxylases in developing rat cerebellum. Neurochemical research, 1991, Volume: 16, Issue:3 Topics: Aging; Animals; Blotting, Northern; Blotting, Western; Cerebellar Cortex; Cerebellum; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Neurons; Nucleic Acid Hybridization; Purkinje Cells; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; RNA, Messenger	1991
On the inhibition of glutamic acid decarboxylase and gamma-aminobutyric acid transaminase by sodium cyanide. Pharmacology & toxicology, 1991, Volume: 69, Issue:4 Topics: 4-Aminobutyrate Transaminase; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Sodium Cyanide	1991
Two forms of the gamma-aminobutyric acid synthetic enzyme glutamate decarboxylase have distinct intraneuronal distributions and cofactor interactions. Journal of neurochemistry, 1991, Volume: 56, Issue:2 Topics: Animals; Antibody Specificity; Axons; Brain; Cats; DNA; Escherichia coli; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immune Sera; Immunoblotting; Mice; Neurons; Pyridoxal Phosphate; Synapses	1991
Neurochemical abnormalities in brains of renal failure patients treated by repeated hemodialysis. Journal of neurochemistry, 1985, Volume: 45, Issue:4 Topics: Adult; Aluminum; Amino Acids; Brain; Brain Chemistry; Choline O-Acetyltransferase; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kidney Failure, Chronic; Methoxyhydroxyphenylglycol; Pyridoxal Phosphate; Renal Dialysis; Tissue Distribution	1985
Competitive inhibition of mouse brain gamma-aminobutyrate aminotransferase by ATP. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 192, Issue:1 Topics: 4-Aminobutyrate Transaminase; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Guanosine Triphosphate; Ketoglutaric Acids; Kinetics; Male; Mice; Mice, Inbred ICR; Pyridoxal Phosphate	1989
Rapid inactivation of brain glutamate decarboxylase by aspartate. Journal of neurochemistry, 1987, Volume: 48, Issue:1 Topics: Animals; Apoenzymes; Aspartic Acid; Brain; Enzyme Reactivators; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Kinetics; Pyridoxal Phosphate; Pyridoxamine; Swine	1987
Pyritinol and the enzymes of gamma-aminobutyric acid (GABA) synthesis and degradation. Physiologia Bohemoslovaca, 1988, Volume: 37, Issue:2 Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Mitochondria; Pyridines; Pyridoxal Phosphate; Pyrithioxin; Rats; Succinate-Semialdehyde Dehydrogenase	1988
Sympathetic stimulation and hypertension in the pyridoxine-deficient adult rat. Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:4 Topics: Animals; Blood Pressure; Dopamine; gamma-Aminobutyric Acid; Hypertension; Hypothalamus; Male; Norepinephrine; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Serotonin; Sympathetic Nervous System; Thyroid Hormones; Vitamin B 6 Deficiency	1988
The effect of repeated electroconvulsive shock on GABA synthesis and release in regions of rat brain. British journal of pharmacology, 1987, Volume: 92, Issue:1 Topics: Animals; Brain; Electroshock; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Seizures; Time Factors	1987
Effect of adrenalectomy on gamma-aminobutyric acid concentrations in the central nervous system. Journal of neurochemistry, 1986, Volume: 46, Issue:1 Topics: Adrenalectomy; Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamine; Liver; Male; Pyridoxal Phosphate; Rats	1986
Some properties of guinea pig brain glutamate decarboxylase and its inhibition by the convulsant allylglycine (2-amino-4-pentenoic acid). Journal of neurochemistry, 1974, Volume: 23, Issue:2 Topics: Aging; Allyl Compounds; Amino Acids; Animals; Anions; Brain; Carbon Radioisotopes; Carboxy-Lyases; Cations, Divalent; Cations, Monovalent; Central Nervous System Stimulants; Chromatography, Gel; Cytosol; Dialysis; Enzyme Activation; Female; gamma-Aminobutyric Acid; Glutamates; Glycine; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Pyridoxal Phosphate; Rats; Semicarbazides; Species Specificity; Ultracentrifugation	1974
Gamma-aminobutyric acid: drug-induced elevation in monkey brain. Journal of neurochemistry, 1974, Volume: 23, Issue:2 Topics: Acetates; Aminobutyrates; Animals; Brain; Carbon Radioisotopes; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Haplorhini; Humans; Huntington Disease; Hydroxylamines; Isoniazid; Ketoglutaric Acids; Male; Pyridoxal Phosphate; Species Specificity; Time Factors; Transaminases	1974
Effects of acute and chronic pentobarbitone on the gamma-aminobutyric acid system in rat brain. Biochemical pharmacology, 1974, Jul-01, Volume: 23, Issue:13 Topics: Aminobutyrates; Animals; Brain; Carboxy-Lyases; gamma-Aminobutyric Acid; Glutamates; Pentobarbital; Pyridoxal Phosphate; Rats; Time Factors; Transaminases	1974
[Changes in nucleoprotein metabolism in the rat brain. II. Effect of the administration of a combination of oxalacetic acid, alpha-ketoglutaric acid and pyridoxal-5-phosphate in normal and fatigued animalsA1]. Bollettino della Societa italiana di biologia sperimentale, 1974, Dec-30, Volume: 50, Issue:23-24 Topics: Animals; Brain; Drug Combinations; Fatigue; gamma-Aminobutyric Acid; Ketoglutaric Acids; Male; Nucleoproteins; Nucleotides; Oxaloacetates; Pyridoxal Phosphate; Rats; RNA	1974
Conversion of glucose to neurotransmitter amino acids in the brains of young and aging rats. Experimental gerontology, 1980, Volume: 15, Issue:6 Topics: Age Factors; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Female; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamine; Neurotransmitter Agents; Pyridoxal Phosphate; Rats	1980
Changes in the amino acid content of nerve endings (synaptosomes) induced by drugs that alter the metabolism of glutamate and gamma-aminobutyric acid. Journal of neurochemistry, 1984, Volume: 42, Issue:1 Topics: Amino Acids; Aminooxyacetic Acid; Animals; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrazines; Isoniazid; Male; Mice; Pyridoxal Phosphate; Pyridoxine; Synaptosomes; Valproic Acid	1984
Incorporation of 14C from glucose into amino acids in brain in vitro in the presence of organo- and inorganic lead and pyridoxal phosphate. Life sciences, 1983, Dec-05, Volume: 33, Issue:23 Topics: Amino Acids; Animals; Brain; Brain Stem; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lead; Male; Organometallic Compounds; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tetraethyl Lead	1983
Comparative characterization of glutamate decarboxylase in crude homogenates of oviduct, ovary, and hypothalamus. Journal of neurochemistry, 1984, Volume: 43, Issue:6 Topics: Animals; Carbon Dioxide; Fallopian Tubes; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hypothalamus; Kinetics; Ovary; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Temperature	1984
[Antiepileptic effects of complex therapy with vitamins and anticonvulsant preparations (experimental findings)]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:6 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Drug Therapy, Combination; gamma-Aminobutyric Acid; Mice; Niacinamide; Pantothenic Acid; Pentylenetetrazole; Phenobarbital; Pyridoxal Phosphate; Seizures; Vitamin E; Vitamins	1982
Inhibition of GABA binding by pyridoxal and pyridoxal phosphate. The International journal of biochemistry, 1980, Volume: 11, Issue:3-4 Topics: Animals; gamma-Aminobutyric Acid; Male; Pyridoxal; Pyridoxal Phosphate; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes	1980
Inhibition of mouse brain synaptosomal gamma-aminobutyric acid transport by pyridoxal 5'-phosphate. Biochemical and biophysical research communications, 1980, Dec-16, Volume: 97, Issue:3 Topics: Animals; Biological Transport; Brain; gamma-Aminobutyric Acid; Kinetics; Mice; Pyridoxal Phosphate; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes	1980
The role of zinc and zinc-binding proteins in regulation of glutamic acid decarboxylase in brain. Progress in clinical and biological research, 1984, Volume: 144A Topics: Adenosine Triphosphate; Animals; Brain; Carrier Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Models, Biological; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Receptors, Cell Surface; Receptors, GABA-A; Zinc	1984
[Use of nicotinamide and pyridoxal-5-phosphate to treat experimental epilepsy]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:6 Topics: Animals; Cats; Drug Therapy, Combination; gamma-Aminobutyric Acid; Niacinamide; Penicillins; Pyridoxal Phosphate; Seizures; Strychnine	1981
Inhibitors of crayfish glutamic acid decarboxylase. Neurochemical research, 1984, Volume: 9, Issue:7 Topics: Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Astacoidea; Drug Interactions; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Ions; Nervous System; Pyridoxal Phosphate; Semicarbazides; Sulfhydryl Compounds	1984
Convulsant activity of pyridoxal sulphate and phosphonoethyl pyridoxal: antagonism by GABA and its synthetic analogues. Neuropharmacology, 1983, Volume: 22, Issue:7 Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain Chemistry; Convulsants; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraventricular; Male; Pyridoxal; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1983
Consequences of brain monoamine changes in the pyridoxine-deficient young rat. Progress in clinical and biological research, 1984, Volume: 144A Topics: Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Kinetics; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Tissue Distribution; Vitamin B 6 Deficiency	1984
Anticonvulsant activity of muscimol and gamma-aminobutyric acid against pyridoxal phosphate-induced epileptic seizures. Journal of neurochemistry, 1981, Volume: 36, Issue:1 Topics: Animals; Brain; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Injections, Intraventricular; Male; Muscimol; Pyridoxal Kinase; Pyridoxal Phosphate; Rats; Time Factors	1981
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. Nature genetics, 1995, Volume: 11, Issue:1 Topics: Alkaline Phosphatase; Animals; Brain Chemistry; Calcification, Physiologic; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; Genes, Lethal; Humans; Hypophosphatasia; Mice; Mice, Neurologic Mutants; Paralysis; Phenotype; Pyridoxal Phosphate; Species Specificity; Tooth Abnormalities; Vitamin B 6 Deficiency	1995
Time-dependent inhibition of gamma-aminobutyric acid aminotransferase, by 3-hydroxybenzylhydrazine. Bioorganic & medicinal chemistry, 1995, Volume: 3, Issue:5 Topics: 4-Aminobutyrate Transaminase; Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Hydrazines; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Swine; Time Factors	1995
Anxiety disorder and pyridoxal phosphate--a possible association. The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12 Topics: Anxiety Disorders; Benzodiazepines; gamma-Aminobutyric Acid; Humans; Pyridoxal Phosphate	1994
Glutamate in pyridoxine-dependent epilepsy: neurotoxic glutamate concentration in the cerebrospinal fluid and its normalization by pyridoxine. Pediatrics, 1994, Volume: 94, Issue:3 Topics: Adrenocorticotropic Hormone; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Genes, Recessive; Glutamates; Glutamic Acid; Head; Humans; Infant; Intellectual Disability; Male; Neurotransmitter Agents; Pyridoxal Phosphate; Pyridoxine	1994
Convulsions and inhibition of glutamate decarboxylase by pyridoxal phosphate-gamma-glutamyl hydrazone in the developing rat. Neurochemical research, 1994, Volume: 19, Issue:2 Topics: Animals; Behavior, Animal; Brain; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Pyridoxal Phosphate; Rats; Rats, Wistar	1994
GABA production in rat islets of Langerhans. Diabetes, 1993, Volume: 42, Issue:10 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aminooxyacetic Acid; Animals; Aspartic Acid; Citrates; Cyclohexanecarboxylic Acids; Cytoplasmic Granules; Cytosol; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Hydrogen-Ion Concentration; Insulin; Islets of Langerhans; Malates; Male; Microsomes; Mitochondria; Pyridoxal Phosphate; Rats; Rats, Wistar	1993
Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities. Protein science : a publication of the Protein Society, 1995, Volume: 4, Issue:11 Topics: 4-Aminobutyrate Transaminase; Amino Acid Sequence; Animals; Binding Sites; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hydrogen Bonding; Isoenzymes; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology; Structure-Activity Relationship; Substrate Specificity; Swine; Vigabatrin	1995
Modulation of extracellular GABA levels in the retina by activation of glial P2X-purinoceptors. British journal of pharmacology, 1998, Volume: 124, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Female; gamma-Aminobutyric Acid; Male; Neuroglia; Neuropeptides; Platelet Aggregation Inhibitors; Potassium Chloride; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana temporaria; Rats; Rats, Wistar; Receptors, Purinergic P2X2; Retina; Thionucleotides	1998
Chemical inactivation of bacterial GABA aminotransferase. Biochemistry and molecular biology international, 1998, Volume: 46, Issue:1 Topics: 4-Aminobutyrate Transaminase; Binding Sites; Enzyme Inhibitors; gamma-Aminobutyric Acid; Ketoglutaric Acids; Kinetics; Mercuric Chloride; p-Chloromercuribenzoic Acid; Pyridoxal Phosphate	1998
Seizures induced by intracerebral administration of pyridoxal-5'-phosphate: effect of GABAergic drugs and glutamate receptor antagonists. Neuropharmacology, 2001, Volume: 41, Issue:5 Topics: Animals; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Motor Activity; Pyridoxal Phosphate; Rats; Rats, Wistar; Seizures	2001
Enzymatic characterization of a recombinant isoform hybrid of glutamic acid decarboxylase (rGAD67/65) expressed in yeast. Journal of biotechnology, 2002, Aug-07, Volume: 97, Issue:2 Topics: Catalysis; Enzyme Stability; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Isoenzymes; Pyridoxal Phosphate; Reproducibility of Results; Saccharomyces cerevisiae; Sensitivity and Specificity; Substrate Specificity; Temperature; Time Factors	2002
Studies on the GABA pathway. II. The lack of effect of pyridoxal phosphate on GABA-KGA transaminase inhibition induced by amino-oxyacetic acid. Biochemical pharmacology, 1961, Volume: 8 Topics: 4-Aminobutyrate Transaminase; Amino Acids; Biochemical Phenomena; Coenzymes; gamma-Aminobutyric Acid; Pyridoxal Phosphate	1961
CYCLOSERINE INHIBITION OF GAMMA-AMINOBUTYRIC-ALPHA-KETOGLUTARIC TRANSAMINASE. Biochemical pharmacology, 1964, Volume: 13 Topics: Aldehydes; Aminobutyrates; Animals; Brain; Cats; Cycloserine; Enzyme Inhibitors; Escherichia coli; gamma-Aminobutyric Acid; Guinea Pigs; Haplorhini; Ketoglutaric Acids; Pharmacology; Pyridoxal Phosphate; Rats; Research; Succinates; Transaminases	1964
THE EFFECTS OF HYDRAZINES ON RAT BRAIN 5-HYDROXYTRYPTAMINE, NOREPINEPHRINE, AND GAMMA-AMINOBUTYRIC ACID. Biochemical pharmacology, 1964, Volume: 13 Topics: Aminobutyrates; Cerebellum; Cerebral Cortex; Chromatography; Diencephalon; Fluorescence; gamma-Aminobutyric Acid; Hydrazines; Medulla Oblongata; Mesencephalon; Norepinephrine; Pharmacology; Pyridoxal Phosphate; Rats; Research; Seizures; Serotonin; Toxicology	1964
Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1 Topics: 4-Aminobutyrate Transaminase; Anticonvulsants; Crystallography, X-Ray; gamma-Aminobutyric Acid; Image Processing, Computer-Assisted; Iron-Sulfur Proteins; Models, Molecular; Molecular Conformation; Protein Conformation; Pyridoxal Phosphate; Vigabatrin	2004
A successful treatment with pyridoxal phosphate for West syndrome in hypophosphatasia. Pediatric neurology, 2004, Volume: 30, Issue:3 Topics: Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electroencephalography; Fatal Outcome; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Hypophosphatasia; Infant; Infant, Newborn; Male; Pyridoxal Phosphate; Spasms, Infantile; Treatment Outcome	2004
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator. Journal of molecular biology, 2004, Jul-16, Volume: 340, Issue:4 Topics: 4-Aminobutyrate Transaminase; Bacillus subtilis; Base Sequence; DNA Footprinting; DNA-Binding Proteins; Enzyme Activation; gamma-Aminobutyric Acid; Gene Deletion; Gene Expression Regulation, Bacterial; Models, Biological; Molecular Sequence Data; Promoter Regions, Genetic; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Fusion Proteins; Repressor Proteins; Sequence Analysis, DNA; Trans-Activators; Transcriptional Activation	2004
Lack of ATP-evoked GABA and glutamate release in the hippocampus of P2X7 receptor-/- mice. Neuroreport, 2004, Oct-25, Volume: 15, Issue:15 Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Benzenesulfonates; Electric Stimulation; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Mice; Mice, Knockout; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tritium	2004
Age-dependent changes of pyridoxal phosphate synthesizing enzymes immunoreactivities and activities in the gerbil hippocampal CA1 region. Mechanisms of ageing and development, 2005, Volume: 126, Issue:12 Topics: Age Factors; Animals; Antibodies; Blotting, Western; Brain; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Humans; Immunohistochemistry; Mice; Microscopy, Fluorescence; Phosphorylation; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxaminephosphate Oxidase; Rats; Time Factors	2005
GABA-induced calcium signaling in cultured enteric neurons is reinforced by activation of cholinergic pathways. Neuroscience, 2006, May-12, Volume: 139, Issue:2 Topics: Acetylcholine; Animals; Baclofen; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Isonicotinic Acids; Myenteric Plexus; Neurons; Nicotinic Antagonists; Ondansetron; Pyridoxal Phosphate; Serotonin Antagonists; Signal Transduction	2006
Cross-inhibitory interactions between GABAA and P2X channels in myenteric neurones. The European journal of neuroscience, 2006, Volume: 23, Issue:12 Topics: Adenosine Triphosphate; Animals; Calcium; Female; GABA Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guinea Pigs; Male; Myenteric Plexus; Neurons; Patch-Clamp Techniques; Picrotoxin; Pyridoxal Phosphate; Receptors, GABA-A; Receptors, Purinergic P2; Receptors, Purinergic P2X	2006
Quantal release of ATP in mouse cortex. The Journal of general physiology, 2007, Volume: 129, Issue:3 Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Neurons; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Glutamate; Suramin	2007
Production of gamma-aminobutyric acid by Streptococcus salivarius subsp. thermophilus Y2 under submerged fermentation. Amino acids, 2008, Volume: 34, Issue:3 Topics: Chromatography, High Pressure Liquid; Culture Media; Fermentation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydrogen-Ion Concentration; Pyridoxal Phosphate; Sodium Glutamate; Streptococcus; Temperature; Time Factors	2008
Time course of changes in pyridoxal 5'-phosphate (vitamin B6 active form) and its neuroprotection in experimental ischemic damage. Experimental neurology, 2007, Volume: 206, Issue:1 Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Astrocytes; Brain Infarction; Brain Ischemia; Cytoprotection; Disease Models, Animal; Down-Regulation; Enzyme Activation; gamma-Aminobutyric Acid; Gerbillinae; Glutamate Decarboxylase; Hippocampus; Immunohistochemistry; Isoenzymes; Neural Inhibition; Neurons; Neuroprotective Agents; Phosphoric Monoester Hydrolases; Pyramidal Cells; Pyridoxal Phosphate; Time Factors; Up-Regulation	2007
Anticonvulsant characteristics of pyridoxyl-gamma-aminobutyrate, PL-GABA. Neuropharmacology, 2008, Volume: 54, Issue:6 Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Drug Tolerance; Electrophysiology; Electroshock; Enzyme Inhibitors; Epilepsy; gamma-Aminobutyric Acid; Gerbillinae; Magnesium; Male; Mice; Mice, Inbred BALB C; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Seizures; Tissue Distribution	2008
GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled by presynaptic purinergic receptors, modulating Ca2+ influx. Cell calcium, 2008, Volume: 44, Issue:6 Topics: Adenosine Triphosphate; Animals; Calcium Signaling; Cerebellar Cortex; Cerebellum; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Models, Biological; Presynaptic Terminals; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Purkinje Cells; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Presynaptic; Receptors, Purinergic P2	2008
PLP catabolism: identification of the 2-(Acetamidomethylene)succinate hydrolase gene in Mesorhizobium loti MAFF303099. Biochemistry, 2008, Jun-10, Volume: 47, Issue:23 Topics: Alphaproteobacteria; Bacterial Proteins; Cloning, Molecular; DNA Primers; Escherichia coli; gamma-Aminobutyric Acid; Hydrolases; Kinetics; Pseudomonas; Pyridoxal Phosphate; Recombinant Proteins; Succinate-Semialdehyde Dehydrogenase	2008
Purinergic type 2 receptors at GABAergic synapses on ventral tegmental area dopamine neurons are targets for ethanol action. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1 Topics: Adenosine Triphosphate; Animals; Ethanol; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Sodium Channels; Suramin; Synapses; Tetrodotoxin; Ventral Tegmental Area	2008
Pathway-dependent modulation by P2-purinoceptors in the mouse retina. The European journal of neuroscience, 2008, Volume: 28, Issue:1 Topics: Action Potentials; Adenosine Triphosphate; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Inhibitory Postsynaptic Potentials; Mice; Mice, Transgenic; Pyridazines; Pyridoxal Phosphate; Receptors, Purinergic P2; Retina; Signal Transduction; Strychnine	2008
Purification and biochemical characterisation of a novel glutamate decarboxylase from rice bran. Journal of the science of food and agriculture, 2010, Apr-30, Volume: 90, Issue:6 Topics: Calcium; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Hydrogen-Ion Concentration; Molecular Structure; Oryza; Pyridoxal Phosphate; Seeds; Substrate Specificity; Temperature	2010
Mammalian retinal horizontal cells are unconventional GABAergic neurons. Journal of neurochemistry, 2011, Volume: 116, Issue:3 Topics: Animals; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Neural Inhibition; Neural Pathways; Pyridoxal Phosphate; Retina; Retinal Horizontal Cells; RNA, Messenger; Synaptic Transmission; Vision, Ocular	2011
Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons. Journal of neurophysiology, 2011, Volume: 106, Issue:1 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Atropine; Carbachol; Dioxanes; gamma-Aminobutyric Acid; Glycine; Indoles; Inhibitory Postsynaptic Potentials; Male; Mecamylamine; Melitten; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Antagonists; Norepinephrine; Purinergic P2X Receptor Antagonists; Pyridoxal Phosphate; Rats; Serotonin Antagonists; Substantia Gelatinosa; Synaptic Transmission; Tropisetron	2011
Pyridoxal 5'-phosphate (PLP) deficiency might contribute to the onset of type I diabetes. Medical hypotheses, 2012, Volume: 78, Issue:1 Topics: Autoimmunity; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Islets of Langerhans; Models, Biological; Pyridoxal Phosphate	2012
Theoretical study on HF elimination and aromatization mechanisms: a case of pyridoxal 5' phosphate-dependent enzyme. The Journal of organic chemistry, 2012, Jul-06, Volume: 77, Issue:13 Topics: 4-Aminobutyrate Transaminase; gamma-Aminobutyric Acid; Hydrofluoric Acid; Models, Molecular; Molecular Structure; Pyridoxal Phosphate; Quantum Theory	2012
Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5'-phosphate, GABA and anti-epileptic drugs. Disease models & mechanisms, 2012, Volume: 5, Issue:6 Topics: Animals; Anticonvulsants; Behavior, Animal; Carbon; Folic Acid; gamma-Aminobutyric Acid; Larva; Models, Neurological; Neurons; Neurotoxins; Pentylenetetrazole; Primidone; Pyridoxal Phosphate; Pyridoxine; Seizures; Swimming; Zebrafish	2012
Robust production of gamma-amino butyric acid using recombinant Corynebacterium glutamicum expressing glutamate decarboxylase from Escherichia coli. Enzyme and microbial technology, 2012, Aug-10, Volume: 51, Issue:3 Topics: Biotechnology; Corynebacterium glutamicum; Culture Media; Escherichia coli; Fermentation; gamma-Aminobutyric Acid; Genetic Engineering; Glutamate Decarboxylase; Pyridoxal Phosphate; Recombinant Proteins	2012
Quantum chemistry studies of the catalysis mechanism differences between the two isoforms of glutamic acid decarboxylase. Journal of molecular modeling, 2013, Volume: 19, Issue:2 Topics: Biocatalysis; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Isoenzymes; Kinetics; Lysine; Protein Structure, Secondary; Protons; Pyridoxal Phosphate; Quantum Theory; Thermodynamics; Tyrosine	2013
Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-29, Volume: 110, Issue:44 Topics: Bacillus subtilis; Dimerization; Evolution, Molecular; gamma-Aminobutyric Acid; Gene Expression Regulation, Bacterial; Models, Molecular; Protein Conformation; Pyridoxal Phosphate; Transcription Factors	2013
Characterization of a glutamate decarboxylase (GAD) gene from Lactobacillus zymae. Biotechnology letters, 2014, Volume: 36, Issue:9 Topics: Amino Acid Sequence; Base Sequence; Chromatography, Thin Layer; Coenzymes; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; Food Microbiology; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lactobacillus; Molecular Sequence Data; Molecular Weight; Pyridoxal Phosphate; Recombinant Proteins; Temperature	2014
Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator. Molecular microbiology, 2015, Volume: 95, Issue:2 Topics: Amino Acids; Bacillus subtilis; Bacterial Proteins; Crystallography, X-Ray; DNA-Binding Proteins; DNA, Bacterial; gamma-Aminobutyric Acid; Gene Expression Regulation, Bacterial; Promoter Regions, Genetic; Protein Binding; Protein Biosynthesis; Protein Stability; Protein Structure, Tertiary; Pyridoxal Phosphate; Transaminases; Transcription Factors; Transcription, Genetic	2015
Evaluation of improved γ-aminobutyric acid production in yogurt using Lactobacillus plantarum NDC75017. Journal of dairy science, 2015, Volume: 98, Issue:4 Topics: China; Culture Media; Fermentation; gamma-Aminobutyric Acid; Humans; Lactobacillus plantarum; Odorants; Pyridoxal Phosphate; Sodium Glutamate; Taste; Temperature; Yogurt	2015
Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator. Journal of biochemistry, 2015, Volume: 158, Issue:3 Topics: 4-Aminobutyrate Transaminase; Bacillus subtilis; Bacterial Proteins; Escherichia coli; gamma-Aminobutyric Acid; Gene Expression Regulation, Bacterial; Helix-Turn-Helix Motifs; Protein Folding; Protein Structure, Tertiary; Pyridoxal Phosphate; Structural Homology, Protein; Succinate-Semialdehyde Dehydrogenase; Trans-Activators	2015
Decrease in pyridoxal-5'-phosphate concentration and increase in pyridoxal concentration in rat plasma by 4'-O-methylpyridoxine administration. Nutrition research (New York, N.Y.), 2015, Volume: 35, Issue:7 Topics: Animals; Brain; Disease Models, Animal; Foodborne Diseases; gamma-Aminobutyric Acid; Ginkgo biloba; Humans; Male; Pyridoxal; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Rats, Wistar; Seeds; Vitamin B 6 Deficiency; Vitamin B Complex	2015
Molecular dynamics simulations of apo, holo, and inactivator bound GABA-at reveal the role of active site residues in PLP dependent enzymes. Proteins, 2016, Volume: 84, Issue:7 Topics: 4-Aminobutyrate Transaminase; Animals; Catalytic Domain; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Molecular Docking Simulation; Molecular Dynamics Simulation; Pyridoxal Phosphate; Pyridoxamine; Swine; Vigabatrin	2016
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor. Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:1 Pt A Topics: Bacillus subtilis; Bacterial Proteins; Base Sequence; Circular Dichroism; DNA, Bacterial; gamma-Aminobutyric Acid; Microscopy, Atomic Force; Models, Molecular; Mutant Proteins; Nucleic Acid Conformation; Promoter Regions, Genetic; Protein Binding; Protein Domains; Pyridoxal Phosphate; Repetitive Sequences, Nucleic Acid; Sequence Alignment; Spectrophotometry, Ultraviolet; Static Electricity; Transcription Factors	2017
GABA production and structure of gadB/gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota. Anaerobe, 2016, Volume: 42 Topics: Bacterial Proteins; Bacteroidetes; Bifidobacterium; DNA, Bacterial; Firmicutes; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Gene Expression; Glutamate Decarboxylase; Humans; Lactobacillus; Membrane Proteins; Metagenome; Proteobacteria; Pyridoxal Phosphate; Sodium Glutamate	2016
Neuromuscular features of hypophosphatasia. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:5S2 Topics: Adult; Alkaline Phosphatase; Animals; Biomarkers; Brain Diseases; Chronic Pain; Disease Models, Animal; Ethanolamines; gamma-Aminobutyric Acid; Humans; Hypophosphatasia; Muscle Hypotonia; Muscular Diseases; Pyridoxal Phosphate; Seizures; Vitamin B Complex	2017
Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice. Biochimica et biophysica acta. Molecular basis of disease, 2019, Volume: 1865, Issue:1 Topics: Animals; Anxiety; Behavior, Animal; Brain; Cognition; Dopamine; Epinephrine; Erythrocytes; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Mice; Mice, Knockout; Models, Animal; Muscle, Skeletal; Neurotransmitter Agents; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Psychomotor Performance; Pyridoxal Phosphate; Serotonin; Spatial Learning; Vitamin B 6	2019
Crystal structure of γ-aminobutyrate aminotransferase in complex with a PLP-GABA adduct from Corynebacterium glutamicum. Biochemical and biophysical research communications, 2019, 06-30, Volume: 514, Issue:3 Topics: 4-Aminobutyrate Transaminase; Amino Acid Sequence; Catalytic Domain; Corynebacterium glutamicum; Crystallography, X-Ray; gamma-Aminobutyric Acid; Models, Molecular; Pyridoxal Phosphate; Structural Homology, Protein	2019
Glutamate Decarboxylase (GAD) Extracted from Germinated Rice: Enzymatic Properties and Its Application in Soymilk. Journal of nutritional science and vitaminology, 2019, Volume: 65, Issue:Supplement Topics: Carbon Dioxide; Carboxy-Lyases; Decarboxylation; Dietary Supplements; gamma-Aminobutyric Acid; Germination; Glutamate Decarboxylase; Glutamic Acid; Oryza; Pyridoxal Phosphate; Soy Milk	2019
Conformational transitions induced by γ-amino butyrate binding in GabR, a bacterial transcriptional regulator. Scientific reports, 2019, 12-17, Volume: 9, Issue:1 Topics: Aspartate Aminotransferases; Bacillus subtilis; Binding Sites; gamma-Aminobutyric Acid; Gene Expression Regulation, Bacterial; Helix-Turn-Helix Motifs; Molecular Conformation; Molecular Dynamics Simulation; Protein Binding; Protein Domains; Pyridoxal Phosphate; Transcription Factors; Transcription, Genetic; Transcriptional Activation	2019
A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid. Journal of the American Chemical Society, 2020, 03-11, Volume: 142, Issue:10 Topics: Cyclohexanecarboxylic Acids; Cyclohexylamines; Enzyme Inhibitors; gamma-Aminobutyric Acid; Humans; Hydrocarbons, Fluorinated; Models, Chemical; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Ornithine-Oxo-Acid Transaminase; Protein Binding; Pyridoxal Phosphate	2020
Efficient expression of novel glutamate decarboxylases and high level production of γ-aminobutyric acid catalyzed by engineered Escherichia coli. International journal of biological macromolecules, 2020, Oct-01, Volume: 160 Topics: Escherichia coli; Fermentation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Kinetics; Lactobacillus; Pyridoxal Phosphate; Temperature	2020
Enhancing the production of γ-aminobutyric acid in Escherichia coli BL21 by engineering the enzymes of the regeneration pathway of the coenzyme factor pyridoxal 5'-phosphate. World journal of microbiology & biotechnology, 2021, Jul-08, Volume: 37, Issue:8 Topics: Biosynthetic Pathways; Coenzymes; Escherichia coli; gamma-Aminobutyric Acid; Metabolic Engineering; Pyridoxal Phosphate; Sodium Glutamate	2021
Gamma aminobutyric acid (GABA) production in Escherichia coli with pyridoxal kinase (pdxY) based regeneration system. Enzyme and microbial technology, 2022, Volume: 155 Topics: Escherichia coli; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Pyridoxal Kinase; Pyridoxal Phosphate	2022
Rational Design, Synthesis, and Mechanism of (3 Journal of the American Chemical Society, 2022, 03-30, Volume: 144, Issue:12 Topics: 4-Aminobutyrate Transaminase; Carboxylic Acids; Enzyme Inhibitors; gamma-Aminobutyric Acid; Humans; Kinetics; Liver Neoplasms; Molecular Docking Simulation; Ornithine-Oxo-Acid Transaminase; Phenylacetates; Pyridoxal Phosphate	2022