pyridoxal phosphate has been researched along with cysteine in 250 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 143 (57.20) | 18.7374 |
| 1990's | 32 (12.80) | 18.2507 |
| 2000's | 32 (12.80) | 29.6817 |
| 2010's | 32 (12.80) | 24.3611 |
| 2020's | 11 (4.40) | 2.80 |
| Authors | Studies |
|---|---|
| Ohisalo, JJ | 1 |
| Morris, HP; Reynolds, RD | 1 |
| Chen, SS; Engel, PC | 1 |
| Boettcher, B; Martinez-Carrion, M | 1 |
| Chatagner, F; Portemer, C | 1 |
| Schonbeck, ND; Shafer, JA; Skalski, M | 1 |
| Creveling, RK; Mazelis, M | 1 |
| Chwaliński, S; Krzystyniak, K; Ryzewski, J | 1 |
| Higgins, H; Miles, EW | 1 |
| Snell, EE; Suelter, CH | 1 |
| Blanco, I; Grau, M; Mengod, G; Palacios, JM; Picatoste, F | 1 |
| Goriachenkova, EV; Kazarian, RA | 1 |
| Goriachenkova, EV; Rabinkov, AG; Tolosa, EA | 1 |
| Braunstein, AE; Goryachenkova, EV | 1 |
| Floss, HG; Potts, R; Schleicher, E | 1 |
| Bayón, A; Possani, LD; Tapia, R | 1 |
| Chatagner, F; Pierre, Y | 1 |
| Akopyan, TN; Braunstein, AE; Goryachenkova, EV | 1 |
| Rassin, DK; Sturman, JA | 1 |
| Fukushima, K; Masada, M; Tamura, G | 1 |
| Kalita, CC; Kerman, JD; Strecker, HJ | 1 |
| Choi, SY; Esaki, N; Soda, K; Yoshimura, T | 1 |
| Douce, R; Droux, M; Martin, J; Sajus, P | 1 |
| Gergely, P; Pallagi, E; Vereb, G | 1 |
| Barrett, J; Walker, J | 1 |
| Fujimoto, H; Haneda, M; Nakatsuka, M; Nisimoto, Y; Nomura, S; Ohta, T; Shibata, Y; Takeuchi, F; Tamai, T; Tsubouchi, R | 1 |
| Leoncini, R; Marinello, E; Pagani, R; Terzuoli, L; Vannoni, D | 1 |
| Böck, A; Boesmiller, K; Forchhammer, K | 1 |
| Kayastha, AM; Miles, EW | 1 |
| Engström, A; Neujahr, HY; Sejlitz, T; Wernstedt, C | 1 |
| Brzović, P; Dunn, MF; Greene, RC; Holbrook, EL | 1 |
| Keleti, T; Leoncini, R; Marinello, E; Pagani, R | 1 |
| Ahmed, SA; Kawasaki, H; Miles, EW; Morita, H; Nagata, S | 1 |
| McGowan, C | 1 |
| Lapin, IP; Ryzhov, IV | 1 |
| Hargrove, JL; Wichman, RD | 1 |
| Kiick, DM; Phillips, RS | 2 |
| Dobryszycki, P; Kochman, M | 1 |
| Bhatnagar, D; Puri, RN; Roskoski, R | 1 |
| Higaki, T; Morino, Y; Nagashima, F; Tanase, S; Yamasaki, M | 1 |
| Fukazawa, H; Ichihara, S; Ichimoto, N; Tateishi, M; Tomisawa, H; Yamamoto, I | 1 |
| Angelaccio, S; Hopkins, S; Schirch, V; Villar, E | 1 |
| Carton, D; Kint, JA | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Chatagner, F; de Billy, G; Ipaktchi, M; Lefauconnier, JM; Portemer, C | 1 |
| Chatagner, F; de Billy, G; Lefauconnier, JM; Portemer, C | 1 |
| Reynolds, RD; Thompson, SD | 1 |
| Andrews, MJ; Turner, JM | 1 |
| Bruno, R; Rinaudo, MT | 1 |
| Hultquist, DE; Passon, PG; Reed, DW | 1 |
| Degani, Y; Nyc, JF; Smith, EL; Veronese, FM | 1 |
| Cozzani, I; Gennari, G; Jori, G; Santoni, C; Tamburro, AM | 1 |
| Pestaña, A; Sandoval, IV; Sols, A | 1 |
| Barker, HA; Jeng, IM; Somack, R | 1 |
| Barboni, E; Costa, M; Granata, F; Pensa, B; Scandurra, R | 1 |
| Khomutov, RM; Metzler, DE; Yang, IY | 1 |
| Lipsett, MN | 1 |
| York, SS | 1 |
| Barboza, V; Fernandez, E; Pulgar, J | 1 |
| De Marco, C; Fadda, MB; Rinaldi, A | 1 |
| Bocharov, AL; Demidkina, TV; Karpeiskii, MY; Polyanovskii, OL | 1 |
| Klungsoyr, L | 1 |
| Baldwin, RL; Goldberg, ME | 1 |
| Blethen, SL; Boeker, EA; Snell, EE | 1 |
| Becker, MA; Kredich, NM; Tomkins, GM | 1 |
| Kumagai, H; Matsui, H; Ogata, K; Ohkishi, H; Yamada, H | 1 |
| Dowhan, W; Snell, EE | 1 |
| Conn, EE; Floss, HG; Hadwiger, L | 1 |
| Crews, L; Mazelis, M | 1 |
| Davis, CH; Krebs, EG; Schliselfeld, LH | 1 |
| Kumagai, H; Nagate, T; Yamada, H; Yoshida, H | 1 |
| Ehrlich, J; Helmreich, E; Pfeuffer, T | 2 |
| Posner, BI | 1 |
| Nath, M; Sanwal, GG | 1 |
| Asmar, JA; Daghir, NJ; Sifri, M | 1 |
| Flavin, M; Posner, BI | 1 |
| Costa, MT; Giarnieri, D; Wolf, AM | 1 |
| Braunstein, AE; Goryachenkova, EV; Tolosa, EA; Willhardt, IH; Yefremova, LL | 1 |
| Fukui, T; Kamogawa, A | 1 |
| Parker, VH; Stonard, MD | 1 |
| Flavin, M; Guggenheim, S | 2 |
| Diven, WF; Johnston, MM | 1 |
| Adams, E | 1 |
| Martinez-Carrion, M; Peterson, DL | 1 |
| Dainty, RH | 1 |
| Chatagner, F; Gicquel, Y; Portemer, C; Tixier, M | 1 |
| Barker, HA; Chirpich, TP; Costilow, RN; Zappia, V | 1 |
| Chalmers, FT; Finkelstein, JD | 1 |
| Brown, MS; Edwards, WA; Laster, L; Loeb, PM; Mudd, SH | 1 |
| Greenberg, DM; Kashiwamata, S | 1 |
| De Marco, C; Rinaldi, A | 1 |
| Smith, IK; Thompson, JF | 1 |
| Diller, A; Schirch, LV | 1 |
| Giovanelli, J; Mudd, SH | 1 |
| Brown, FC; Gordon, PH | 1 |
| De Issaly, IS | 1 |
| Chatagner, F; Durieu-Trautmann, O; Rain, MC | 1 |
| Kraus, P | 1 |
| DeMoss, RD; Gopinathan, KP | 1 |
| Mella, K; Ortanderl, F; Pfleiderer, G; Stock, A | 1 |
| Mahadevan, S; Shukla, PS | 1 |
| Meister, A; Tate, SS | 2 |
| Hasenbank, G; Körber, F; Siegmund, P | 1 |
| Brown, FC; Hudgins, WR; Roszell, JA | 1 |
| Fischer, EH; Hedrick, JL; Shaltiel, S | 3 |
| Damjanovich, S; Kleppe, K | 1 |
| Angeletti, E; Haertelt, M | 1 |
| Klein, SM; Sagers, RD | 1 |
| Graves, DJ; Johnson, GF | 1 |
| Marino, G; Scardi, V; Zito, R | 1 |
| Belugina, OP; Paducheva, AL | 1 |
| Linkswiler, H | 1 |
| Falcone, G; Giambanco, V | 1 |
| Beimer, N; Creveling, RK; Mazelis, M | 1 |
| Meister, A; Miles, EW | 1 |
| Chocat, P; Esaki, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Chocat, P; Esaki, N; Karai, N; Nakamura, T; Soda, K; Tanaka, H | 1 |
| Esaki, N; Karai, N; Soda, K; Tanaka, H | 1 |
| Bazaes, S; Beytía, E; Eyzaguirre, J; Gómez, I; Jabalquinto, AM; Solís de Ovando, F | 1 |
| Engel, PC; Gould, KG | 1 |
| King, KM; Stipanuk, MH | 1 |
| Higgins, W; Miles, EW | 1 |
| Federiuk, CS; Shafer, JA | 1 |
| Morzycka, E; Paszewski, A | 1 |
| Beffa, F; Casella, A; Marinello, E; Pagani, R | 1 |
| Chen, HY; Demidkina, TV; Phillips, RS | 1 |
| Gloss, LM; Kirsch, JF | 1 |
| Huang, DY; Ichikawa, Y | 1 |
| Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
| Ahmed, SA; Banik, U; Miles, EW; Parris, KD; Ruvinov, SB; Sackett, DL; Yang, XJ | 1 |
| Cook, PF; McClure, GD | 1 |
| Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Silva, R | 1 |
| Leoncini, R; Marinello, E; Pagani, R; Pizzichini, M; Terzuoli, L | 1 |
| Cash, VL; Dean, DR; White, RH; Zheng, L | 1 |
| Esaki, N; Kagamiyama, H; Kim, DW; Kuramitsu, S; Matsushima, Y; Soda, K; Yoshimura, T | 1 |
| Esaki, N; Kim, DW; Satoh, E; Soda, K; Yoshimura, T | 1 |
| Kahana, C; Tobias, KE | 1 |
| Flint, DH | 1 |
| Katiyar, SS; Sheikh, S | 1 |
| Honma, M; Ito, H; Kiuchi, M; Matsui, H; Murakami, T | 1 |
| Cho, SW; Lee, JE | 1 |
| Bertoldi, M; Castellani, S; Dominici, P; Moore, PS; Voltattorni, CB | 1 |
| Guerranti, R; Leoncini, R; Marinello, E; Pagani, R; Ponticelli, F; Terzuoli, L; Vannoni, D | 1 |
| Han, Q; Hoffman, RM; Lenz, M; Miljkovic, D; Sun, X; Tan, X; Tan, Y; Tang, L; Xu, M | 1 |
| Bates, CJ; Berge, T; Drabløs, PA; Hervig, T; Hetland, O; Kristensen, O; Mansoor, MA; Osland, A; Pentieva, K; Rolfsen, S; Vefring, H | 1 |
| Clausen, T; Huber, R; Laber, B; Messerschmidt, A; Steegborn, C; Streber, W | 1 |
| Harrison, DH; Miziorko, HM; Runquist, JA | 1 |
| Esaki, N; Fujii, T; Hata, Y; Kurihara, T; Maeda, M; Mihara, H | 1 |
| Bartunik, HD; Bourenkow, GP; Clausen, T; Huber, R; Kaiser, JT; Steinbacher, S | 1 |
| Cook, PF; Tai, CH | 1 |
| Finkelstein, JD | 1 |
| Burkhard, P; Cook, PF; Jansonius, JN; Tai, CH | 1 |
| Cook, AM; Laue, H | 1 |
| Banerjee, R; Green, EL; Loehr, TM; Taoka, S | 1 |
| Lehman, TD; Ortwerth, BJ | 1 |
| Goodman, JE; Helzlsouer, KJ; Lavigne, JA; Selhub, J; Strickland, PT; Wu, K; Yager, JD | 1 |
| Spies, HS; Steenkamp, DJ; Vogt, RN | 1 |
| Esaki, N; Fujii, T; Hata, Y; Kato, S; Kurihara, T; Mihara, H | 1 |
| Anders, MW; Bruschi, SA; Cooper, AJ | 1 |
| Banerjee, R; Kabil, O; Lepore, BW; Ojha, S; Ringe, D; Taoka, S | 1 |
| Kimura, H | 1 |
| Beck, GJ; Greene, T; Kusek, JW; Levey, AS; Sarnak, MJ; Selhub, J; Wang, SR | 1 |
| Cook, PF; Karsten, WE | 1 |
| BERGERET, B; CHATAGNER, F; FROMAGEOT, C | 2 |
| CHATAGNER, F; SAURET-IGNAZI, G | 1 |
| BERGEL, F; BRAY, RC; HARRAP, KR | 1 |
| WUST, CJ | 1 |
| MACKAY, D | 1 |
| DELAVIER-KLUTCHKO, C; FLAVIN, M; SLAUGHTER, C | 1 |
| FROMAGEOT, P; POUZAT, J; RODERICK, UR | 1 |
| GONZALEZ, E; HORVATH, A | 1 |
| JACOBSEN, JG; SMITH, LH; THOMAS, LL | 1 |
| DEMARCO, C | 1 |
| NEWTON, WA; SNELL, EE | 1 |
| DURIO, SN; FLANNERY, WL | 1 |
| FLAVIN, M; SLAUGHTER, C | 2 |
| FLAVIN, M; SEGAL, A | 1 |
| FROMAGEOT, P; SENTENAC, A | 1 |
| MEISTER, A; NOVOGRODSKY, A; SODA, K | 1 |
| BOMBARDIERI, G; COLETTA, M; DEMARCO, C | 1 |
| SAARI, JC; SCHULTZE, MO | 1 |
| HOPE, DB | 1 |
| CHATAGNER, F; JOLLES-BERGERET, B; LABOUESSE, J | 1 |
| Bertoldi, M; Borri Voltattorni, C; Cellini, B | 1 |
| Emery, PW; Johnston, K; Obeid, OA | 1 |
| Bollinger, JM; Drennan, CL; Tirupati, B; Vey, JL | 1 |
| Behshad, E; Bollinger, JM; Parkin, SE | 1 |
| Bittner, F; Heidenreich, T; Mendel, RR; Wollers, S | 1 |
| Alber, D; Alberto, JM; Berthelot, A; Demougeot, C; Figard, H; Gaume, V; Gueant, JL; Guilland, JC; Mougin, F | 1 |
| Papenbrock, J; Riemenschneider, A; Schmidt, A; Wegele, R | 1 |
| Bettati, S; Campanini, B; Cook, PF; Huang, B; Mozzarelli, A; Roderick, SL; Salsi, E; Speroni, F | 1 |
| Amrhein, N; Fitzpatrick, TB; Raschle, T | 1 |
| Bonner, ER; Cahoon, RE; Jez, JM; Knapke, SM | 1 |
| Giangregorio, N; Indiveri, C; Palmieri, F; Tonazzi, A | 1 |
| Kessler, D | 1 |
| Field, MJ; Garcia-Viloca, M; Gonzalez-Lafont, A; Lluch, JM; Puig, E | 1 |
| Callery, PS; Cooper, AJ; Krasnikov, BF; Niatsetskaya, ZV; Petros, WP; Pinto, JT; Younis, IR | 1 |
| Chang, CC; Chang, JH; Chien, YW; Huang, SY; Tsen, JH; Yang, HT | 1 |
| Agren, D; Oehlmann, W; Schneider, G; Schnell, R; Singh, M | 1 |
| Chua, JH; Deng, LW; Huang, S; Moore, PK; Sivaraman, J; Tan, CH; Yew, WS | 1 |
| Baxter, GF; Elsey, DJ; Fowkes, RC | 1 |
| Buring, JE; Cook, NR; Lee, IM; Lin, J; Manson, JE; Selhub, J; Song, Y; Zhang, SM | 1 |
| Allen, GF; Clayton, PT; Footitt, EJ; Heales, SJ; Mills, PB; Oppenheim, M | 1 |
| Burstyn, JN; Freeman, KM; Kraus, JP; Majtan, T; Smith, AT; Su, Y | 1 |
| Begley, TP; Ealick, SE; Krishnamoorthy, K; Tran, TH | 1 |
| Helgadóttir, S; Ling, J; Sinapah, S; Söll, D | 1 |
| Chen, F; Deng, Z; He, X; Liang, J; Lin, K; Qian, T; Wang, Z; Wu, G; You, D; Zhang, Y; Zhang, Z | 1 |
| Kezuka, Y; Nonaka, T; Yoshida, Y | 1 |
| Paietta, JV; Reveal, BS | 1 |
| Cho, E; Fuchs, CS; Giovannucci, EL; Nan, H; Paul, L; Rosner, B; Selhub, J; Wu, K | 1 |
| Cai, B; Cui, QH; Fan, X; Geng, B; Gong, Y; Liao, F; Tang, C; Xu, GH; Yang, J; Zeng, Q; Zheng, Y | 1 |
| Chiang, FF; Huang, SC; Huang, YC; Lan, YC; Wang, HM; Yang, MH | 1 |
| Charan, M; Habib, S; Kumar, B; Siddiqi, MI; Singh, N; Srivastava, K | 1 |
| Banerjee, R; Chi, YY; DeRatt, BN; Gregory, JF; Kabil, O; Ralat, MA | 1 |
| Anufrieva, NV; Demidkina, TV; Faleev, NG; Fedorova, OS; Kuznetsov, NA; Kuznetsova, AA; Morozova, EA; Nikulin, AD; Revtovich, SV | 1 |
| Fontecilla-Camps, JC; Nicolet, Y; Pagnier, A | 1 |
| Black, KA; Dos Santos, PC | 1 |
| Schneider, G; Schnell, R; Sriram, D | 1 |
| Ding, H; Lu, J; Tan, G; White, RH; Yang, J; Zhang, T | 1 |
| Borowczyk, K; Głowacki, R; Jakubowski, H; Stachniuk, J | 1 |
| Liu, W; Wang, M; Zhang, Q; Zhao, Q | 1 |
| Altegoer, F; Bange, G; Blauenburg, B; Fage, CD; Linne, U; Marahiel, MA; Mielcarek, A | 1 |
| Allegrini, A; Astegno, A; Dominici, P; La Verde, V | 1 |
| Stone, E; Yan, W; Zhang, YJ | 1 |
| Commichau, FM; Rosenberg, J; Yeak, KC | 1 |
| Berkowitz, DB; Hill, M; Kreinbring, CA; Liu, C; Liu, D; McCune, CD; Petsko, GA; Ringe, D; Tu, Y | 1 |
| Gylling, B; Häggström, J; Hallmans, G; Johansson, I; Midttun, Ø; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Ulvik, A; Van Guelpen, B | 1 |
| Bertoldi, M; Bisello, G; Borri Voltattorni, C; Grottesi, A; Montioli, R; Paiardini, A; Rossignoli, G | 1 |
| Dweik, R; Grove, D; Hine, C; Minkler, P; Wang, R; Willard, B; Yang, J | 1 |
| Mothersole, RG; Wolthers, KR | 1 |
| Barondeau, DP; Patra, S | 1 |
| Chen, C; Chen, S; Deng, Z; Gao, H; Hong, L; Jiang, S; Lai, C; Li, N; Liu, G; Liu, L; Tan, P; Wang, L; Wu, D; Wu, G; Xing, M | 1 |
| Głowacka, IE; Głowacki, R; Piechocka, J; Wrońska, M | 1 |
| Guo, L; Lin, J; Lin, JF; Lin, S; Wang, Y; Yang, X | 1 |
| Haavik, J; Kursula, P; Loris, R; Luan, W; Mahootchi, E; Muruganandam, G; Raasakka, A | 1 |
| Agnoli, C; Amiano, P; Ardanaz, E; Chiodini, P; Clasen, JL; Cross, AJ; Eriksen, AK; Ferrari, P; Gunter, M; Heath, AK; Huybrechts, I; Johansson, M; Kaaks, R; Katzke, V; Midttun, Ø; Muller, DC; Overvad, K; Palli, D; Park, JY; Riboli, E; Rodriguez-Barranco, M; Sacerdote, C; Santiuste, C; Scelo, G; Schmidt, JA; Schulze, MB; Tjønneland, A; Tumino, R; Ueland, PM; Ulvik, A; Van Puyvelde, H; Weiderpass, E; Zamora-Ros, R | 1 |
| Bandyopadhyay, P; Biswas, R; Dutta, S; Laxman, S; Pramanick, I; Ps, S; Rajmani, RS; Singh, A; Singh, S; Sreedharan, S | 1 |
| Makarova, NE; Manta, B; Mariotti, M | 1 |
| Bias, T; Geldenhuys, WJ; Konkle, ME; Kruger, J; Kunk, C; Mann, A; Markitan, J; Mendoza, G; Menze, MA; Nath, A | 1 |
| Chen, C; Krishna, V; Mulay, P | 1 |
| Caubrière, D; Couturier, J; Moseler, A; Rouhier, N | 1 |
| Głowacki, R; Piechocka, J; Wyszczelska-Rokiel, M | 1 |
11 review(s) available for pyridoxal phosphate and cysteine
| Article | Year |
|---|---|
The pyridoxal-phosphate-dependent enzymes exclusively catalyzing reactions of beta-replacement.
Topics: Amino Acids; Animals; Carboxy-Lyases; Chick Embryo; Chloromercuribenzoates; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cystine; Kinetics; Lyases; Nitriles; Pyridoxal Phosphate; Rats; Serine; Sulfhydryl Compounds; Thiocyanates | 1976 |
[Endogenous convulsants (review)].
Topics: Amino Acids; Animals; Carbolines; Cats; Cerebral Cortex; Convulsants; Cysteic Acid; Cysteine; Disease Models, Animal; Dogs; Estrogens; Folic Acid; Homocysteine; Kynurenine; Methionine; Mice; Neurotransmitter Agents; Prostaglandins; Pyridoxal Phosphate; Quinolinic Acid; Quinolinic Acids; Rats; Seizures; Spinal Cord | 1986 |
O-acetylserine sulfhydrylase.
Topics: Amino Acid Sequence; Cysteine; Cysteine Synthase; Enterobacteriaceae; Models, Molecular; Molecular Sequence Data; Plants; Pyridoxal Phosphate | 2000 |
Pathways and regulation of homocysteine metabolism in mammals.
Topics: Animals; Cystathionine; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Homocysteine; Isoenzymes; Kinetics; Mammals; Methionine; Methionine Adenosyltransferase; Organ Specificity; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylhomocysteine; S-Adenosylmethionine; Sulfur; Tetrahydrofolates | 2000 |
Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism.
Topics: Animals; Carbon-Sulfur Lyases; Cysteine; Energy Metabolism; Humans; Hydrocarbons, Fluorinated; Lyases; Mitochondria; Pyridoxal Phosphate | 2002 |
Hydrogen sulfide as a neuromodulator.
Topics: Animals; Brain Chemistry; Calcium; Calmodulin; Cattle; Central Nervous System Diseases; Corticotropin-Releasing Hormone; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Heme; Hippocampus; Humans; Hydrogen Sulfide; Hypothalamus; Long-Term Potentiation; Mice; Muscle Proteins; Muscle Relaxation; Nerve Tissue Proteins; Neurotransmitter Agents; Nitric Oxide; Pyridoxal Phosphate; Rats; Synaptic Transmission | 2002 |
Enzymatic activation of sulfur for incorporation into biomolecules in prokaryotes.
Topics: Bacterial Proteins; Binding Sites; Coenzymes; Cysteine; Enzyme Precursors; Lyases; Models, Molecular; Nitrogen; Nitrogen Fixation; Prokaryotic Cells; Pyridoxal Phosphate; Sulfur; Sulfur Compounds; Thiazoles; Ubiquitin; Vitamins | 2006 |
Shared-intermediates in the biosynthesis of thio-cofactors: Mechanism and functions of cysteine desulfurases and sulfur acceptors.
Topics: Bacterial Proteins; Biosynthetic Pathways; Carbon-Sulfur Lyases; Coenzymes; Cysteine; Iron-Sulfur Proteins; Metalloproteins; Models, Molecular; Molybdenum Cofactors; Protein Structure, Tertiary; Pteridines; Pyridoxal Phosphate; Sulfur | 2015 |
Pyridoxal-phosphate dependent mycobacterial cysteine synthases: Structure, mechanism and potential as drug targets.
Topics: Anti-Bacterial Agents; Cysteine; Cysteine Synthase; Humans; Mycobacterium tuberculosis; Pyridoxal Phosphate | 2015 |
The selenophosphate synthetase family: A review.
Topics: Adenosine Triphosphate; Cysteine; Hormones; Ligases; Phosphates; Phosphotransferases; Pyridoxal Phosphate; Selenium; Selenium Compounds; Selenocysteine; Selenoproteins | 2022 |
Diversity and roles of cysteine desulfurases in photosynthetic organisms.
Topics: Carbon-Sulfur Lyases; Cysteine; Iron; Iron-Sulfur Proteins; Pyridoxal Phosphate; Sulfur | 2023 |
2 trial(s) available for pyridoxal phosphate and cysteine
| Article | Year |
|---|---|
Plasma total homocysteine response to oral doses of folic acid and pyridoxine hydrochloride (vitamin B6) in healthy individuals. Oral doses of vitamin B6 reduce concentrations of serum folate.
Topics: Administration, Oral; Adult; Cholesterol; Cysteine; Dipeptides; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Lipoproteins; Male; Middle Aged; Norway; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Vitamin B 12 | 1999 |
Homocysteine, cysteine, and B vitamins as predictors of kidney disease progression.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Biomarkers; Blood Pressure Monitoring, Ambulatory; Cysteine; Diet, Protein-Restricted; Disease Progression; Female; Folic Acid; Homocysteine; Humans; Kidney Diseases; Male; Middle Aged; Prognosis; Pyridoxal Phosphate; Risk Factors; Vitamin B 12 | 2002 |
237 other study(ies) available for pyridoxal phosphate and cysteine
| Article | Year |
|---|---|
On the inactivation of hepatic tyrosine aminotransferase.
Topics: Animals; Anura; Cycloheximide; Cysteine; Cystine; Enzyme Repression; Epinephrine; Fructose; Glucose; Liver; Pyridoxal Phosphate; Rana temporaria; Rats; Tyrosine Transaminase | 1977 |
Effects of dietary vitamin B6 on the in vitro inactivation of rat tyrosine aminotransferase in host liver and Morris hepatomas.
Topics: Animals; Cysteine; In Vitro Techniques; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred ACI; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1979 |
Reversible modification of pig heart mitochondrial malate dehydrogenase by pyridoxal 5'-phosphate.
Topics: Borohydrides; Cysteine; Kinetics; Malate Dehydrogenase; Malates; Mitochondria, Muscle; Myocardium; NAD; Pyridoxal Phosphate; Temperature; Time Factors | 1975 |
Magnetic resonance relaxation rates in the study of complexes of ligands with spin-labeled aspartate transaminase.
Topics: Aspartate Aminotransferases; Binding Sites; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Ligands; Magnetic Resonance Spectroscopy; Piperidines; Pyridoxal Phosphate; Spin Labels | 1978 |
Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties.
Topics: Animals; Borohydrides; Carboxy-Lyases; Cysteine; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Molecular Weight; Norepinephrine; Penicillamine; Protein Conformation; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Sulfinic Acids; Temperature | 1975 |
Reactions of pyrzdoxal 5'-phosphate, 6-aminocaproic acid, cysteine, and penicilamine. Models for reactions of Schiff base linkages in pyridoxal 5'-phosphate-requiring enymes.
Topics: Aminocaproates; Anaerobiosis; Cysteine; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Penicillamine; Pyridoxal Phosphate; Schiff Bases; Thiazoles | 1975 |
Purification and properties of S-alkyl-L-cysteine lyase from seedlings of Acacia farnesiana Willd.
Topics: Acacia; Amino Acids; Cysteine; Hydrogen-Ion Concentration; Kinetics; Lyases; Molecular Weight; Pyridoxal Phosphate | 1975 |
Studies on the influence of thiols on lymphocytes (T-type lymphocytes) functions.
Topics: Animals; Cysteine; Oxidation-Reduction; Penicillamine; Pyridoxal Phosphate; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; T-Lymphocytes; Thymus Gland; Uridine | 1978 |
Studies of the function and location of two cysteines in the beta 2 subunit of tryptophan synthase.
Topics: Cysteine; Dithionitrobenzoic Acid; Escherichia coli; Kinetics; Molecular Weight; Pyridoxal Phosphate; Sulfhydryl Reagents; Tryptophan Synthase | 1978 |
Assay of pyridoxal phosphate and pyridoxamine phosphate, employing S-o-nitrophenyl-L-cysteine, a chromogenic substrate of tryptophanase.
Topics: Cysteine; Escherichia coli; Lyases; Nitrobenzenes; Organophosphorus Compounds; Pyridoxal Phosphate; Pyridoxamine; Tryptophanase | 1979 |
Pyridoxal-5'-phosphate as a cofactor for rat brain histidine decarboxylase.
Topics: Animals; Apoenzymes; Borohydrides; Brain; Buffers; Carboxy-Lyases; Cysteine; Dialysis; Edetic Acid; Female; Histidine Decarboxylase; Hydroxylamines; In Vitro Techniques; Isoniazid; Male; Phenylhydrazines; Pyridoxal Phosphate; Rats; Semicarbazides | 1978 |
[Alliinase: purification and chief physico-chemical properties].
Topics: Carbon-Sulfur Lyases; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Electrophoresis, Polyacrylamide Gel; Garlic; Isoelectric Focusing; Lyases; Molecular Weight; Plants; Plants, Medicinal; Pyridoxal Phosphate | 1978 |
[Resolution of beta-cyanoalanine synthase and recombination of its apoenzyme with pyridoxal-5'-phosphate and its analogs].
Topics: Apoenzymes; Apoproteins; Binding Sites; Binding, Competitive; Cysteine; Enzyme Activation; Kinetics; Lyases; Nitriles; Plants; Pyridoxal Phosphate | 1978 |
Stereochemistry of the formation of cysteine by O-acetylserine sulfhydrase.
Topics: Cysteine; Escherichia coli; Lyases; Molecular Conformation; Pyridoxal Phosphate; Stereoisomerism; Structure-Activity Relationship | 1976 |
Kinetics of brain glutamate decarboxylase. Inhibition studies with N-(5'-phosphopyridoxyl) amino acids.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Brain; Carboxy-Lyases; Cysteine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamates; Kinetics; Mice; Pyridoxal Phosphate | 1977 |
Functional arginine in the active center of rat liver cystathionase.
Topics: Animals; Arginine; Binding Sites; Binding, Competitive; Cystathionine gamma-Lyase; Cysteine; Diacetyl; Homoserine; Liver; Lyases; Pyridoxal Phosphate; Rats | 1977 |
Beta-cyanoalanine synthase: purification and characterization.
Topics: Amino Acids; Aminooxyacetic Acid; Carbon-Sulfur Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cycloserine; Cysteine; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Kinetics; Lyases; Molecular Weight; Penicillamine; Plants; Propionates; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1975 |
Cysteine sulfinic acid decarboxylase in rat brain: effect of vitamin B6 deficiency on soluble and particulate components.
Topics: Animals; Aspartic Acid; Brain; Carboxy-Lyases; Cysteine; Pyridoxal Phosphate; Pyridoxine; Rats; Sulfinic Acids; Time Factors; Vitamin B 6 Deficiency | 1975 |
Cysteine synthase from rape leaves.
Topics: Chromatography, Gel; Cysteine; Kinetics; Lyases; Macromolecular Substances; Molecular Weight; Plants; Protein Conformation; Pyridoxal Phosphate; Serine; Subcellular Fractions | 1975 |
Preparation and properties of ornithine-oxo-acid aminotransferase of rat kidney. Comparison with the liver enzyme.
Topics: Amino Acids; Animals; Canavanine; Cysteine; Ketoglutaric Acids; Kidney; Kinetics; Liver; Molecular Weight; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Temperature; Transaminases | 1976 |
Reaction mechanism of glutamate racemase, a pyridoxal phosphate-independent amino acid racemase.
Topics: Amino Acid Isomerases; Bacterial Proteins; Cysteine; Deuterium; Enzyme Activation; Glutamates; Glutamic Acid; Kinetics; Magnetic Resonance Spectroscopy; Pediococcus; Pyridoxal Phosphate; Sulfhydryl Compounds; Tritium | 1992 |
Purification and characterization of O-acetylserine (thiol) lyase from spinach chloroplasts.
Topics: Acetyltransferases; Amino Acids; Blotting, Western; Chloroplasts; Chromatography, Liquid; Cross Reactions; Cysteine; Cysteine Synthase; Electrophoresis, Polyacrylamide Gel; Epitopes; Mitochondria; Plants; Pyridoxal Phosphate; Serine; Serine O-Acetyltransferase; Spectrometry, Fluorescence | 1992 |
Phosphorylation-induced conformational changes in the phosphorylase ab hybrid as revealed by resolution of pyridoxal 5'-phosphate with imidazole citrate and cysteine.
Topics: Adenosine Monophosphate; Allosteric Regulation; Animals; Cysteine; Imidazoles; Kinetics; Ligands; Phosphorylases; Phosphorylation; Protein Conformation; Pyridoxal Phosphate; Rabbits; Temperature | 1992 |
Biochemical characterisation of the enzyme responsible for "activated L-serine sulphydrase" activity in nematodes.
Topics: Animals; Anthelmintics; Cystathionine beta-Synthase; Cysteamine; Cysteine; Haemonchus; Homocysteine; Kinetics; Liver; Nematoda; Nippostrongylus; Phenols; Pyridoxal Phosphate; Rats; Substrate Specificity | 1992 |
On kynureninase activity.
Topics: Animals; Apoenzymes; Benzothiazoles; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrolases; Kynurenine; Liver; Magnesium; Male; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Xanthurenates | 1991 |
High-performance liquid chromatography of thiazolidinic compounds obtained by condensation of pyridoxal 5'-phosphate or pyridoxal with aminothiols (L- or D-cysteine, cysteamine, L-cysteine ethyl ester).
Topics: Chromatography, High Pressure Liquid; Cysteamine; Cysteine; Liver; Pyridoxal; Pyridoxal Phosphate; Thiazoles; Tissue Extracts | 1991 |
The function of selenocysteine synthase and SELB in the synthesis and incorporation of selenocysteine.
Topics: Bacterial Proteins; Binding Sites; Chromatography, Thin Layer; Cysteine; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Organoselenium Compounds; Oxidation-Reduction; Protein Biosynthesis; Pyridoxal Phosphate; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Amino Acyl; Selenocysteine; Transferases | 1991 |
A colorimetric assay for a pyridoxal phosphate-dependent beta-replacement reaction with L-cysteine: application to studies of wild-type and mutant tryptophan synthase alpha 2 beta 2 complexes.
Topics: Colorimetry; Cysteine; Escherichia coli; Methylene Blue; Mutagenesis, Site-Directed; Phenylenediamines; Pyridoxal Phosphate; Salmonella typhimurium; Sulfides; Tryptophan Synthase | 1991 |
Amino acid sequences around the pyridoxal-5'-phosphate-binding sites of phenol hydroxylase.
Topics: Amino Acid Sequence; Binding Sites; Cysteine; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Trichosporon | 1990 |
Reaction mechanism of Escherichia coli cystathionine gamma-synthase: direct evidence for a pyridoxamine derivative of vinylglyoxylate as a key intermediate in pyridoxal phosphate dependent gamma-elimination and gamma-replacement reactions.
Topics: Alanine; Allylglycine; Carbon-Oxygen Lyases; Cysteine; Escherichia coli; Fatty Acids, Monounsaturated; Homoserine; Kinetics; Lyases; Molecular Structure; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Spectrophotometry, Ultraviolet | 1990 |
Double inhibition of L-threonine dehydratase by aminothiols.
Topics: Animals; Binding Sites; Binding, Competitive; Cysteamine; Cysteine; Dithiothreitol; Edetic Acid; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Threonine Dehydratase | 1989 |
The beta subunit of tryptophan synthase. Clarification of the roles of histidine 86, lysine 87, arginine 148, cysteine 170, and cysteine 230.
Topics: Arginine; Binding Sites; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Histidine; Lysine; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase | 1989 |
Influence of vitamin B6 status on aspects of lead poisoning in rats.
Topics: Amino Acids; Animals; Coenzymes; Cysteine; Diet; Glutathione; Glutathione Reductase; Lead Poisoning; Liver; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Statistics as Topic; Vitamin B 6 Deficiency | 1989 |
A cystine-dependent inactivator of tyrosine aminotransferase co-purifies with gamma-cystathionase (cystine desulfurase).
Topics: Animals; Chromatography; Cystathionine gamma-Lyase; Cysteine; Cystine; Female; Isoelectric Focusing; Isoelectric Point; Kinetics; Liver; Lyases; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Tyrosine Transaminase | 1987 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Fluorescence resonance energy transfer studies on the proximity between lysine-107 and cysteine-239 in rabbit muscle aldolase.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Cysteine; Energy Transfer; Fructose-Bisphosphate Aldolase; Lysine; Muscles; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Rabbits; Spectrometry, Fluorescence | 1988 |
Inactivation of yeast hexokinase by o-phthalaldehyde: evidence for the presence of a cysteine and a lysine at or near the active site.
Topics: Aldehydes; Binding Sites; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Hexokinase; Kinetics; Lysine; Nucleosides; Nucleotides; o-Phthalaldehyde; Pyridoxal Phosphate; Saccharomyces cerevisiae; Structure-Activity Relationship | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Identification of coenzyme aldimine proton in 1H NMR spectra of pyridoxal 5'-phosphate dependent enzymes: aspartate aminotransferase isoenzymes.
Topics: Aminooxyacetic Acid; Animals; Aspartate Aminotransferases; Cysteine; Isoenzymes; Magnetic Resonance Spectroscopy; Mitochondria, Heart; Neurotransmitter Agents; Protein Binding; Pyridoxal Phosphate; Swine | 1986 |
Purification and characterization of human hepatic cysteine-conjugate beta-lyase.
Topics: Carbon-Sulfur Lyases; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Lyases; Pyridoxal Phosphate; Substrate Specificity; Temperature | 1986 |
Serine hydroxymethyltransferase from Escherichia coli: purification and properties.
Topics: Amino Acid Sequence; Cysteine; Escherichia coli; Glycine Hydroxymethyltransferase; Kinetics; Molecular Weight; Protein Denaturation; Pyridoxal Phosphate; Spectrum Analysis; Substrate Specificity; Transferases | 1985 |
New evidence for the identity of homoserine deaminase and cystathionase in human liver.
Topics: Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Child; Colorimetry; Cysteine; Humans; Hydro-Lyases; Hydroxybutyrates; Keto Acids; Liver; Pyridoxal Phosphate | 1971 |
Significance of the glycine cleavage system in glycine and serine catabolism in avian liver.
Topics: Ammonium Chloride; Animals; Arylformamidase; Bicarbonates; Carbon Dioxide; Carbon Isotopes; Chickens; Columbidae; Cycloserine; Cysteine; Enzyme Activation; Folic Acid; Glycine; Hydroxylamines; Hypoxanthines; L-Serine Dehydratase; Liver; Male; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Semicarbazides; Serine; Species Specificity; Subcellular Fractions; Transferases; Uric Acid | 1971 |
Redistribution of pyridoxal phosphate in the male rat liver as a result of repeated injections of hydrocortisone.
Topics: Alanine Transaminase; Animals; Aspartic Acid; Carboxy-Lyases; Cystathionine; Cysteine; Dose-Response Relationship, Drug; Homocysteine; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Lyases; Male; Pyridoxal Phosphate; Rats; Seasons; Serine; Time Factors; Tyrosine Transaminase | 1973 |
Effect of cortisol on the level of pyridoxal phosphate-dependent enzymes in the rat liver: new supports for antagonism between female sex hormones and cortisol.
Topics: Alanine Transaminase; Animals; Body Weight; Carboxy-Lyases; Castration; Cysteine; Female; Homoserine; Hydro-Lyases; Hydrocortisone; L-Serine Dehydratase; Liver; Male; Organ Size; Ovary; Pyridoxal Phosphate; Rats; Sex Factors; Sulfuric Acids; Time Factors; Tyrosine Transaminase | 1973 |
Irreversible inactivation of rat liver tyrosine aminotransferase.
Topics: Animals; Apoproteins; Binding Sites; Centrifugation, Density Gradient; Cross Reactions; Cysteine; Dihydroxyphenylalanine; Drug Stability; Electrophoresis, Disc; Half-Life; Hot Temperature; Hydroxylamines; Ketoglutaric Acids; Kinetics; Liver; Protein Binding; Pyridoxal Phosphate; Rats; Semicarbazides; Structure-Activity Relationship; Time Factors; Tyrosine; Tyrosine Transaminase; Ultrafiltration | 1974 |
Pyridoxal and pyridoxamine phosphate breakdown by an acid phosphatase preparation.
Topics: Acid Phosphatase; Acid-Base Equilibrium; Chemical Phenomena; Chemistry; Colorimetry; Cysteine; Edetic Acid; Fluorides; Histidine; Hydrogen-Ion Concentration; Iodoacetates; Magnesium; Mercaptoethanol; Phosphoric Monoester Hydrolases; Pyridoxal Phosphate; Triticum | 1966 |
Alpha-glucan-phosphorylase in the striated muscle of the developing embryo of Gallus domesticus.
Topics: Adenine Nucleotides; Aging; Animals; Benzoates; Chick Embryo; Chickens; Cyclic AMP; Cysteine; Glucose; Glucosyltransferases; Mercury; Muscles; Phlorhizin; Pyridoxal Phosphate | 1968 |
Purification and properties of a pink copper protein from human erythrocytes.
Topics: Carbamates; Chemical Phenomena; Chemistry; Chromatography; Copper; Cysteine; Dihydrolipoamide Dehydrogenase; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Erythrocytes; Fluorometry; Glutathione Reductase; Humans; Indophenol; Ligases; Lyases; Molecular Weight; Oxidation-Reduction; Oxidoreductases; Peroxidases; Phenylhydrazines; Porphyrins; Propionates; Proteins; Pyridoxal Phosphate; Pyrroles; Quinolines; Spectrophotometry; Ultracentrifugation | 1970 |
Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. III. Isolation and sequences of peptides containing selectively labeled lysine and cysteine residues.
Topics: Amino Acid Sequence; Amino Acids; Aminopeptidases; Binding Sites; Borohydrides; Carbon Radioisotopes; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Cysteine; Electrophoresis, Paper; Ethylmaleimide; Glutamate Dehydrogenase; Leucyl Aminopeptidase; Lysine; NAD; Neurospora; Neurospora crassa; Oxidation-Reduction; Papain; Peptide Fragments; Protein Binding; Pyridoxal Phosphate; Thermolysin; Trypsin | 1974 |
Pyridoxal phosphate-sensitized photoinactivation of glutamate decarboxylase from Clostridium perfringens.
Topics: Amino Acids; Carboxy-Lyases; Chromatography, Ion Exchange; Circular Dichroism; Clostridium perfringens; Cysteine; Glutamates; Histidine; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Oxygen; Photochemistry; Pyridoxal Phosphate; Spectrometry, Fluorescence; Time Factors | 1974 |
Inhibition by homocysteine of serine dehydratase and other pyridoxal 5'-phosphate enzymes of the rat through cofactor blockage.
Topics: Alanine Transaminase; Animals; Cysteine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Liver; Male; Norepinephrine; Penicillamine; Pyridoxal Phosphate; Rats; Spectrophotometry; Stereoisomerism; Tyrosine Transaminase | 1971 |
Ornithine degradation in Clostridium sticklandii; pyridoxal phosphate and coenzyme A dependent thiolytic cleavage of 2-amino-4-ketopentanoate to alanine and acetyl coenzyme A.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Apoproteins; Carbon Radioisotopes; Catalysis; Chromatography, Paper; Clostridium; Coenzyme A; Cysteine; Electrophoresis, Paper; Enzyme Activation; Keto Acids; Ornithine; Pyridoxal Phosphate; Species Specificity; Structure-Activity Relationship; Sulfhydryl Reagents; Thiolester Hydrolases; Valerates | 1974 |
Pantothenoylcysteine-4' -phosphate decarboxylase from horse liver.
Topics: Animals; Carboxy-Lyases; Cattle; Cysteine; Horses; Liver; Organophosphorus Compounds; Pantothenic Acid; Pyridoxal Phosphate; Rabbits; Rats; Subcellular Fractions; Sulfhydryl Compounds; Sulfhydryl Reagents | 1974 |
Reaction of pyridoxal 5'-sulfate with apoenzyme of aspartate aminotransferase. Covalent labeling of the protein with elimination of sulfate.
Topics: Animals; Apoenzymes; Aspartate Aminotransferases; Binding Sites; Circular Dichroism; Cysteine; Cytoplasm; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Myocardium; Organophosphorus Compounds; Oxidation-Reduction; Protein Binding; Pyridoxal; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Schiff Bases; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfuric Acids; Swine | 1974 |
Biosynthesis of 4-thiouridylate. Participation of a sulfurtransferase containing pyridoxal 5'-phosphate.
Topics: Alanine; Aldehydes; Borohydrides; Chromatography; Cysteine; Enzyme Activation; Escherichia coli; Hydroxyapatites; Hydroxylamines; Kinetics; Organophosphorus Compounds; Picolines; Pyridoxal Phosphate; Pyruvates; RNA, Transfer; Serine; Sulfhydryl Compounds; Sulfur Isotopes; Sulfurtransferases; Thiouridine; Uridine | 1972 |
Kinetic spectroscopic studies of substrate and subunit interactions of tryptophan synthetase.
Topics: Alcohols; Catalysis; Cysteine; Deamination; Escherichia coli; Hydro-Lyases; Kinetics; Macromolecular Substances; Mercaptoethanol; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Serine; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan Synthase | 1972 |
Kinetic characteristics of cisteine desulphydrase in the liver and pancreas of different biological species.
Topics: Animals; Chickens; Cystathionine; Cysteine; Dogs; Fishes; Homocysteine; In Vitro Techniques; Kinetics; Liver; Lyases; Mice; Pancreas; Pyridoxal Phosphate; Pyruvates; Rats; Species Specificity; Swine | 1973 |
Pyridoxal phosphate catalyzed alpha-beta elimination of S-gamma-aminopropylcysteine.
Topics: Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Paper; Cysteamine; Cysteine; Homocysteine; Phosphates; Propylamines; Pyridoxal Phosphate; Pyruvates; Spectrophotometry; Spectrophotometry, Ultraviolet | 1973 |
Physicochemical and catalytic properties of aspartate aminotransferase selectively modified at the tyrosine and cysteine residues.
Topics: Animals; Apoproteins; Aspartate Aminotransferases; Binding Sites; Carbon Radioisotopes; Cattle; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Cysteine; Electrophoresis, Paper; Enzyme Activation; Ethylmaleimide; Ketoglutarate Dehydrogenase Complex; Methane; Myocardium; Nitro Compounds; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Tyrosine | 1974 |
Interaction of 8-anilino-1-naphthalenesulfonic acid with holo- and apophosphorylase b. Ligand effects, resolution, and reconstitution with pyridoxal 5'-phosphate.
Topics: Adenosine Monophosphate; Anilino Naphthalenesulfonates; Animals; Apoproteins; Binding Sites; Citrates; Cysteine; Glycerophosphates; Imidazoles; Kinetics; Ligands; Muscles; Phosphorylases; Protein Binding; Pyridoxal Phosphate; Rabbits; Sodium Chloride; Spectrometry, Fluorescence; Temperature | 1974 |
Interactions between the subunits of the tryptophan synthetase of Escherichia coli. Optical properties of an intermediate bound to the alpha-2 beta-2 complex.
Topics: Acrylates; Amino Acids; Catalysis; Centrifugation, Density Gradient; Centrifugation, Zonal; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Hydro-Lyases; Mercaptoethanol; Protein Binding; Pyridoxal Phosphate; Serine; Spectrophotometry | 1967 |
Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme.
Topics: Arginine; Binding Sites; Canavanine; Carboxy-Lyases; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Cysteine; Dialysis; Electrophoresis, Disc; Escherichia coli; Guanidines; Hydrogen-Ion Concentration; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis; Temperature; Ultracentrifugation; Ultraviolet Rays | 1968 |
The purification and characterization of O-acetylserine sulfhydrylase-A from Salmonella typhimurium.
Topics: Amino Acids; Autoradiography; Carbon Isotopes; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Electrophoresis, Disc; Hydro-Lyases; Kinetics; Methods; Molecular Weight; Peptides; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Spectrophotometry; Trypsin; Ultracentrifugation | 1969 |
Tyrosine phenol lyase. I. Purification, crystallization, and properties.
Topics: Alanine; Amino Acids; Ammonia; Catechols; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Culture Media; Cysteine; Electrophoresis; Escherichia coli; Feedback; Kinetics; Lyases; Methods; Molecular Weight; Phenols; Protamines; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Stereoisomerism; Sulfates; Tyrosine; Ultracentrifugation | 1970 |
D-serine dehydratase from Escherichia coli. 3. Resolution of pyridoxal 5'-phosphate and coenzyme specificity.
Topics: Alcohols; Aldehydes; Binding Sites; Buffers; Citrates; Cysteine; Enzyme Activation; Escherichia coli; Hydro-Lyases; Imidazoles; Kinetics; L-Serine Dehydratase; Organophosphonates; Oxidation-Reduction; Phosphates; Picolines; Protein Denaturation; Pyridoxal Phosphate; Serum Albumin, Bovine; Stereoisomerism; Sulfur | 1970 |
Enzymatic formation of beta-cyanoalanine from cyanide.
Topics: Adenosine Triphosphate; Alanine; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cyanides; Cysteine; Edetic Acid; Hydroxylamines; Indicators and Reagents; Isoniazid; Magnesium; Mercury; Plants; Pyridoxal Phosphate; Semicarbazides; Serine | 1965 |
Purification of the alliin lyase of garlic, Allium sativum L.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Cobalt; Cold Temperature; Cysteine; Drug Stability; Edetic Acid; Garlic; Glycerol; Hydrogen-Ion Concentration; Hydroxylamines; Iron; Kinetics; Lyases; Magnesium; Manganese; Plants, Medicinal; Pyridoxal Phosphate; Spectrophotometry; Sulfoxides; Time Factors | 1968 |
A comparison of phosphorylase isozymes in the rabbit.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Antibodies; Chickens; Citrates; Crystallization; Cysteine; Drug Stability; Electrophoresis; Enzyme Activation; Glucosyltransferases; Glycogen; Hexosephosphates; Hydrogen-Ion Concentration; Imidazoles; Immunodiffusion; Isoenzymes; Kinetics; Male; Muscles; Myocardium; Precipitin Tests; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Temperature; Time Factors | 1970 |
Threonine aldolase from Candida humicola. II. Purification, crystallization and properties.
Topics: Aldehyde-Lyases; Ammonium Sulfate; Candida; Chromatography; Chromatography, Gel; Crystallization; Cysteine; Dialysis; Electrophoresis, Disc; Enzyme Activation; Hydroxyapatites; Molecular Weight; Potassium; Protein Binding; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrophotometry; Threonine; Ultracentrifugation | 1972 |
Role of pyridoxal 5'-phosphate in glycogen phosphorylase. I. Synthesis of 3'-O-methylpyridoxal 5'-phosphate N-oxide and pyridoxal 5'-phosphate monomethyl ester and the conversion of the N-oxide to pyridoxal 5'-phosphate by apophosphorylase b from rabbit s
Topics: Acetamides; Alkylation; Animals; Apoproteins; Benzoates; Chromatography, Thin Layer; Cyclic N-Oxides; Cysteine; Darkness; Disulfides; Esters; Glucosyltransferases; Iodoacetates; Light; Muscles; Nitro Compounds; Phosphorylases; Protein Binding; Pyridoxal Phosphate; Rabbits; Radiation Effects; Structure-Activity Relationship; Sulfhydryl Compounds; Ultracentrifugation | 1972 |
Role of pyridoxal 5'-phosphate in glycogen phosphorylase. II. Mode of binding of pyridoxal 5'-phosphate and analogs of pyridoxal 5'-phosphate to apophosphorylase b and the aggregation state of the reconstituted phosphorylase proteins.
Topics: Apoproteins; Azo Compounds; Binding Sites; Borohydrides; Cyclic N-Oxides; Cysteine; Dicarboxylic Acids; Drug Stability; Electrophoresis; Enzyme Activation; Esters; Glucosyltransferases; Hydrogen-Ion Concentration; Imides; Kinetics; Macromolecular Substances; Oxidation-Reduction; Phosphorylases; Protein Binding; Pyridoxal Phosphate; Structure-Activity Relationship; Temperature; Tritium | 1972 |
Cystathionine -synthase: studies on the replacement reaction.
Topics: Catalysis; Chemical Phenomena; Chemistry; Cysteine; Homoserine; Kinetics; Mass Spectrometry; Mathematics; Models, Chemical; Propionates; Pyridoxal Phosphate; Salmonella; Succinates; Sulfhydryl Compounds; Transferases | 1972 |
Threonine dehydratase from goat liver.
Topics: Ammonium Sulfate; Animals; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Cysteine; Goats; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Liver; Pyridoxal Phosphate; Serine; Threonine | 1972 |
Serum aminotransferase activities and plasma free amino acid concentration as criteria for pyridoxine nutritional status of chicks.
Topics: Alanine Transaminase; Amino Acids; Aminobutyrates; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Asparagine; Aspartate Aminotransferases; Body Weight; Chickens; Cysteine; Diet; Feeding Behavior; Glutamine; Glycine; Male; Ornithine; Pyridoxal Phosphate; Pyridoxine; Serine; Taurine; Vitamin B 6 Deficiency | 1972 |
Cystathionine -synthase. Studies of hydrogen exchange reactions.
Topics: Alanine; Aminobutyrates; Catalysis; Chemical Phenomena; Chemistry; Cystathionine; Cysteine; Deuterium; Homoserine; Kinetics; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Salmonella; Serine; Succinates; Tritium | 1972 |
Cleavage of cystine by cystathionase.
Topics: Ammonia; Animals; Catalysis; Chromatography, Gel; Cystathionine; Cysteine; Cystine; Enzyme Activation; Homoserine; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Liver; Oxygen; Pyridoxal Phosphate; Pyruvates; Rats; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfhydryl Compounds | 1972 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
Purification and properties of glycogen phosphorylase from bovine spleen.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acids; Ammonium Sulfate; Animals; Benzoates; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Cysteine; Drug Stability; Electrophoresis, Disc; Enzyme Activation; Fluorides; Glucosephosphates; Glucosyltransferases; Hydrogen-Ion Concentration; Kinetics; Liver; Macromolecular Substances; Molecular Weight; Muscles; Organ Specificity; Phosphorylases; Pyridoxal Phosphate; Rabbits; Sodium; Species Specificity; Spectrophotometry; Spleen; Starch; Sulfates; Sulfhydryl Compounds; Sulfides; Swine; Ultracentrifugation | 1971 |
The metabolism of S-(1,2 dichlorovinyl)-L-cysteine by rat liver mitochondria.
Topics: Alkylation; Ammonia; Animals; Centrifugation, Density Gradient; Cysteine; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Proteins; Pyridoxal Phosphate; Pyruvates; Rats; Semicarbazides; Statistics as Topic; Time Factors; Vinyl Compounds | 1971 |
Cystathionine gamma-synthase. A pyridoxal phosphate enzyme catalyzing rapid exchanges of beta and alpha hydrogen atoms in amino acids.
Topics: Amino Acids; Butyrates; Chemical Phenomena; Chemistry; Cysteine; Homocysteine; Hydro-Lyases; Hydrogen; Ketones; Kinetics; Methionine; Pyridoxal Phosphate; Salmonella; Tritium | 1969 |
Studies on amino acid racemases. I. Partial purification and properties of the alanine racemase from Lactobacillus fermenti.
Topics: Acetates; Alanine; Aminobutyrates; Aspartic Acid; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Computers; Cysteine; Drug Stability; Glutamates; Glutathione; Hydrogen-Ion Concentration; Isomerases; Kinetics; Lactobacillus; Mercaptoethanol; Methods; Models, Biological; Models, Chemical; Pyridoxal Phosphate; Serine; Stereoisomerism; Temperature | 1969 |
Reaction of dithionite and bisulfite with pyridoxal and pyridoxal enzymes.
Topics: Alanine; Alanine Transaminase; Aspartate Aminotransferases; Chemical Phenomena; Chemistry; Cysteine; Enzymes; Isomerases; Pyridoxal Phosphate; Spectrophotometry; Sulfites | 1969 |
The mechanism of transamination. Function of the histidyl residue at the active site of supernatant aspartate transaminase.
Topics: Aspartate Aminotransferases; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Coenzymes; Cysteine; Dicarboxylic Acids; Glutarates; Histidine; Ketoglutaric Acids; Kinetics; Light; Models, Biological; Models, Chemical; Oxidation-Reduction; Pyridoxal Phosphate; Pyridoxine; Radiation Effects; Spectrophotometry; Spectrum Analysis; Sulfinic Acids; Tritium; Ultraviolet Rays | 1970 |
Purification and properties of threonine aldolase from Clostridium pasteurianum.
Topics: Aldehyde-Lyases; Chromatography, Gas; Clostridium; Cysteine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Mercaptoethanol; Pyridoxal Phosphate; Semicarbazides; Threonine | 1970 |
Inactivation of cystathionase and of cysteine sulfinic acid decarboxylase by proteolytic enzymes: effect of pyridoxal phosphate.
Topics: Animals; Carboxy-Lyases; Chymotrypsin; Cysteine; Hydro-Lyases; Liver; Male; Peptide Hydrolases; Pyridoxal Phosphate; Rats; Sulfinic Acids; Trypsin | 1970 |
Lysine 2,3-aminomutase. Purification and properties of a pyridoxal phosphate and S-adenosylmethionine-activated enzyme.
Topics: Acetone; Amino Acids; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Clostridium; Cysteine; Deuterium; Dialysis; Drug Stability; Electrophoresis; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxylamines; Intramolecular Transferases; Iron; Isomerases; Isoniazid; Kinetics; Lysine; Methionine; Methods; Molecular Weight; Nucleosides; Pyridoxal Phosphate; Pyridoxine; Streptomycin; Sulfhydryl Compounds; Temperature; Tritium | 1970 |
Pyridoxine effects on cystathionine synthase in rat liver.
Topics: Amino Acids; Animals; Betaine; Cysteine; Homocysteine; Homocystine; Hydro-Lyases; Liver; Male; Pyridoxal Phosphate; Stimulation, Chemical; Succinates; Transferases; Vitamin B 6 Deficiency | 1970 |
Homocystinuria due to cystathionine synthase deficiency: the effect of pyridoxine.
Topics: Adult; Aldehydes; Autoanalysis; Carbon Isotopes; Chromatography; Cysteine; Diet; Diet Therapy; Enzyme Activation; Female; Fibroblasts; Homocystine; Homocystinuria; Humans; Hydro-Lyases; Keto Acids; L-Serine Dehydratase; Liver; Male; Methionine; Pyridoxal Phosphate; Pyridoxine; Serine; Sulfates; Trypsin | 1970 |
Studies on cystathionine synthase of rat liver. Properties of the highly purified enzyme.
Topics: Amino Acids; Animals; Boron Compounds; Chloromercuribenzoates; Chromatography, Ion Exchange; Cysteine; Dialysis; Drug Stability; Electrophoresis, Disc; Freeze Drying; Glutathione; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Liver; Mercury; Pyridoxal Phosphate; Rats; Spectrophotometry | 1970 |
Pyridoxal phosphate-catalyzed alpha-beta elimination of lanthionine and cystathionine.
Topics: Amino Acids; Ammonia; Chemical Phenomena; Chemistry; Cysteine; Homocysteine; Pyridoxal Phosphate; Pyruvates; Spectrophotometry | 1970 |
Purification and characterization of L-serine transacetylase and O-acetyl-L-serine sulfhydrylase from kidney bean seedlings (Phaseolus vulgaris).
Topics: Acetates; Acyltransferases; Carbon Isotopes; Chemical Precipitation; Chloromercuribenzoates; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cysteine; Ethylmaleimide; Hydrogen-Ion Concentration; Lyases; Plants; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Serine; Sulfates; Sulfhydryl Reagents | 1971 |
Serine transhydroxymethylase. Affinity of the active site for substrates, substrate analogues, and anions.
Topics: Alanine; Aldehydes; Aminoisobutyric Acids; Animals; Benzoates; Binding Sites; Chlorides; Cysteamine; Cysteine; Electrophoresis; Folic Acid; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Models, Biological; Organophosphonates; Phosphates; Potassium; Propionates; Pyridoxal Phosphate; Rabbits; Serine; Spectrophotometry; Stereoisomerism; Sulfates; Sulfhydryl Compounds; Sulfonic Acids; Thermodynamics; Threonine; Transferases; Ultracentrifugation | 1971 |
Transsulfuration in higher plants. Partial purification and properties of beta-cystathionase of spinach.
Topics: Alanine; Amino Acids; Benzoates; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Drug Stability; Edible Grain; Ethylmaleimide; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Models, Structural; Plants; Pyridoxal Phosphate; Pyruvates; Quaternary Ammonium Compounds; Serine; Species Specificity; Spectrophotometry; Stereoisomerism; Sulfates; Sulfides; Sulfur; Triticum | 1971 |
Cystathionine synthase from rat liver: partial purification and properties.
Topics: Amino Acids; Animals; Benzoates; Boron Compounds; Calcium Phosphates; Carbon Isotopes; Chromatography, Gel; Cysteine; Drug Stability; Electrophoresis; Enzyme Activation; Homocysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; L-Serine Dehydratase; Liver; Mercury; Oxidation-Reduction; Protamines; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rats; Serine; Spectrophotometry; Sulfates; Sulfides; Temperature | 1971 |
Cysteine biosynthesis in Pasteurella multocida. Cysteine synthase, purification and properties.
Topics: Adsorption; Aspartate Aminotransferases; Calcium Phosphates; Cell-Free System; Cellulose; Centrifugation, Zonal; Chemical Precipitation; Chromatography, Ion Exchange; Colorimetry; Cysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Ions; Kinetics; Oxidoreductases; Pasteurella; Pyridoxal Phosphate; Serine; Sulfides; Sulfur Isotopes | 1968 |
[Influence of pyridoxal phosphate and some other pyridoxine derivatives on stability, in vitro, of cystathionase and cysteine sulfinic acid decarboxylase].
Topics: Aldehydes; Amines; Amino Acids; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Hot Temperature; Hydro-Lyases; Phosphates; Protein Denaturation; Pyridines; Pyridoxal Phosphate; Pyridoxine; Sulfinic Acids; Urea | 1968 |
The microdetermination of L-glutamic acid decarboxylase with use of 14C-labelled substrate.
Topics: Animals; Biochemistry; Brain; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cysteine; Glutamates; Hydrogen-Ion Concentration; In Vitro Techniques; Mercaptoethanol; Methods; Mice; Microchemistry; Polyethylenes; Pyridoxal Phosphate | 1968 |
Proton retention in the gamma-elimination reaction catalysed by cystathionine gamma-synthase.
Topics: Cysteine; Deuterium; Dinitrophenols; Hydrazines; Hydro-Lyases; Hydrogen; Keto Acids; Magnetic Resonance Spectroscopy; Protons; Pyridoxal Phosphate; Serine; Succinates; Tritium; Water | 1968 |
The role of tris(hydroxymethyl)aminomethane and cysteine in the dissociation of tryptophanase.
Topics: Acrylic Resins; Bacillus; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Cysteine; Hydrogen-Ion Concentration; Lyases; Penicillamine; Pyridoxal Phosphate; Tromethamine; Tryptophan | 1968 |
[On the binding of coenzyme to glutamic-pyruvic transaminase of pig heart].
Topics: Alanine Transaminase; Amino Acids; Animals; Charcoal; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Coenzymes; Cysteine; Dialysis; Electrophoresis; Myocardium; Peptides; Phosphorus Isotopes; Pyridoxal Phosphate; Spectrophotometry; Swine | 1968 |
Indoleacetaldoxime hydro-lyase. II. Purification and properties.
Topics: Ascomycota; Ascorbic Acid; Benzoates; Chelating Agents; Cyanides; Cysteine; Dimercaprol; Ethylmaleimide; Glutathione; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Mercury; Oxidation-Reduction; Pyridoxal Phosphate; Thermodynamics | 1968 |
Studies on the sulfhydryl groups of L-aspartate beta-decarboxylase.
Topics: Amines; Amino Acids; Aspartic Acid; Benzoates; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Electrophoresis; Mercury; Nitrogen; Pyridoxal Phosphate; Spectrum Analysis; Sulfhydryl Compounds; Transaminases | 1968 |
[On the reactions of D- and L-penicillamine with some aldimines of pyridoxal phosphate].
Topics: Alanine Transaminase; Chemical Phenomena; Chemistry; Cysteine; Imines; Ketoglutaric Acids; Penicillamine; Pyridoxal Phosphate; Pyridoxine; Spectrophotometry; Stereoisomerism | 1968 |
Reactions of cyclic amino acid derivatives with the pyridoxal phosphate of cystathionase.
Topics: Aminobutyrates; Chemical Phenomena; Chemistry; Chloromercuribenzoates; Cycloserine; Cysteine; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxybutyrates; Imines; Lactones; Pyridoxal Phosphate; Radiation-Protective Agents | 1969 |
The effects of various vitamin B6 5'-phosphate derivatives on the structure and activities of L-aspartate beta-decarboxylase.
Topics: Alanine; Alcaligenes; Amines; Aspartic Acid; Binding Sites; Carbon Isotopes; Carboxy-Lyases; Chemical Phenomena; Chemistry; Cysteine; Dialysis; Electrophoresis; Fluorometry; Hydrolases; Kinetics; Models, Chemical; Molecular Weight; Pyridoxal Phosphate; Pyridoxine; Pyruvates; Spectrum Analysis; Sulfur; Transaminases | 1969 |
Conformation changes and the mechanism of resolution of glycogen phosphorylase b.
Topics: Adenine Nucleotides; Amines; Animals; Benzoates; Chemical Phenomena; Chemistry; Citrates; Crystallization; Cysteine; Fluorometry; Glucosyltransferases; Glycogen; Guanidines; Imidazoles; Kinetics; Mercury; Models, Chemical; Muscles; Protein Denaturation; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Temperature; Ultracentrifugation; Ultraviolet Rays; Urea | 1969 |
Stereospecific requirements for carbonyl reagents in the resolution and reconstitution of phosphorylase b.
Topics: Aldehydes; Animals; Binding Sites; Boron Compounds; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Dialysis; Glucosyltransferases; Kinetics; Muscles; Protein Denaturation; Pyridoxal Phosphate; Rabbits; Stereoisomerism; Sulfhydryl Compounds; Sulfur Isotopes; Ultracentrifugation; Urea | 1969 |
Studies on the SH groups of phosphorylase b. Reaction with 5,5'-dithiobis-(2-nitrobenzoic acid).
Topics: Adenine Nucleotides; Animals; Benzoates; Chemical Phenomena; Chemistry; Chromatography, Gel; Cysteine; Detergents; Glucosyltransferases; Hexosephosphates; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Mercury; Muscles; Protein Denaturation; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Sulfates; Sulfhydryl Compounds; Sulfides; Ultracentrifugation | 1969 |
[Coenzyme activity of 2-(2-methyl-3-hydroxy-4-pyridyl-5-methylphosphoric)-4-thiazolidinecarboxylic acid].
Topics: Animals; Coenzymes; Cysteine; In Vitro Techniques; Mice; Pyridoxal Phosphate; Thiazoles; Transaminases | 1965 |
Glycine metabolism. II. Kinetic and optical studies on the glycine decarboxylase system from Peptococcus glycinophilus.
Topics: Carboxy-Lyases; Cysteine; Fluorometry; Glycine; In Vitro Techniques; Kinetics; Peptococcus; Pyridoxal Phosphate; Spectrophotometry; Ultraviolet Rays | 1966 |
Circular dichroism and optical rotatory dispersion of glycogen phosphorylase.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Cysteine; Glucosyltransferases; Glycogen; In Vitro Techniques; Muscles; Pyridoxal Phosphate; Rabbits | 1966 |
On the role of pyridoxal 5'-phosphate in phosphorylase. II. Resolution of rabbit muscle phosphorylase b.
Topics: Animals; Chemical Phenomena; Chemistry; Cysteine; Glucosyltransferases; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Kinetics; Muscles; Pyridoxal Phosphate; Rabbits; Ultracentrifugation | 1966 |
Amino acid composition and terminal residues of aspartate aminotransferase from ox heart.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Autoanalysis; Cattle; Cysteine; Myocardium; Nitrogen; Phosphorus; Pyridoxal Phosphate; Tryptophan | 1966 |
[Synthesis of cysteine in skin homogenates].
Topics: Animals; Autoradiography; Culture Techniques; Cysteine; Liver; Pyridoxal Phosphate; Rabbits; Serine; Sheep; Skin; Sulfur Isotopes | 1966 |
Biochemical and physiological changes in vitamin B6 deficiency.
Topics: Alanine Transaminase; Anemia, Hypochromic; Central Nervous System Diseases; Cysteine; Erythrocytes; Humans; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; Pyridoxal Phosphate; Pyridoxine; Serotonin; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1967 |
Synthesis of seleno-amino-acids in cell free extracts of Candida albicans.
Topics: Candida; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Cystine; Glutamates; Pyridoxal Phosphate; Pyruvates; Selenium; Sulfites | 1967 |
Cleavage of L-cystine by soluble enzyme preparations from Brassica species.
Topics: Cysteine; Cystine; Enzymes; In Vitro Techniques; Kinetics; Lyases; Mercaptoethanol; Plants, Edible; Pyridoxal Phosphate | 1967 |
The mechanism of the reaction of beta-hydroxyaspartate with L-aspartate beta-decarboxylase. A new type of pyridoxal 5'-phosphate-enzyme inhibition.
Topics: Alcaligenes; Aldehydes; Amino Acids; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, Gel; Cysteine; Enzymes; Hydrazones; Phenylhydrazines; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfinic Acids | 1967 |
Microbial distribution of selenocysteine lyase.
Topics: Alcaligenes; Bacteria; Cysteine; Cytoplasm; Fungi; Kinetics; Lyases; Pseudomonas; Pyridoxal Phosphate; Selenium; Selenocysteine; Yeasts | 1983 |
Selenocysteine beta-lyase: a novel pyridoxal enzyme.
Topics: Animals; Bacteria; Cysteine; Hydrogen-Ion Concentration; Liver; Lyases; Pyridoxal Phosphate; Selenium; Selenocysteine; Substrate Specificity; Swine; Tissue Distribution | 1984 |
Reaction and regulation mechanisms of selenocysteine beta-lyase.
Topics: Aluminum; Animals; Cysteine; Dithiothreitol; Keto Acids; Liver; Lyases; Magnetic Resonance Spectroscopy; Pyridoxal Phosphate; Pyridoxamine; Selenium; Selenocysteine; Swine | 1984 |
Pig liver phosphomevalonate kinase. 2. Participation of cysteinyl and lysyl groups in catalysis.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Kinetics; Liver; Lysine; Mevalonic Acid; Phosphotransferases; Phosphotransferases (Phosphate Group Acceptor); Pyridoxal Phosphate; Swine | 1980 |
Modification of mouse testicular lactate dehydrogenase by pyridoxal 5'-phosphate.
Topics: Animals; Binding Sites; Coenzymes; Cysteine; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactates; Lysine; Male; Mice; Nucleotides; Pyridoxal Phosphate; Testis | 1980 |
Characteristics of the enzymatic capacity for cysteine desulfhydration in cat tissues.
Topics: Animals; Brain; Cats; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Hydrogen Sulfide; Ketoglutaric Acids; Kidney; Liver; Male; Myocardium; Pyridoxal Phosphate; Rats; Sulfurtransferases; Transaminases | 1982 |
Location of the reactive sulfhydryl residues in the primary sequence of the beta 2 subunit of tryptophan synthase of Escherichia coli.
Topics: Affinity Labels; Amino Acid Sequence; Binding Sites; Cysteine; Escherichia coli; Ethylmaleimide; Macromolecular Substances; Peptide Fragments; Pyridoxal Phosphate; Tryptophan Synthase | 1980 |
Inactivation of D-serine dehydratase by alkylamines via a transimination of enzyme-linked cofactor.
Topics: Amines; Cysteine; Escherichia coli; Kinetics; L-Serine Dehydratase; Potassium; Pyridoxal Phosphate; Structure-Activity Relationship | 1981 |
Cysteine and homocysteine synthesis in Saccharomycopsis lipolytica; identification and characterization of two cysteine synthases.
Topics: Ascomycota; Carbon-Oxygen Lyases; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Homocysteine; Lyases; Multienzyme Complexes; Mutation; Pyridoxal Phosphate; Saccharomyces cerevisiae Proteins; Saccharomycopsis; Substrate Specificity | 1982 |
Specificity of the reaction of rat liver L-serine dehydratase with aminothiols.
Topics: Animals; Cysteine; Kinetics; L-Serine Dehydratase; Liver; Male; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Spectrophotometry; Stereoisomerism; Substrate Specificity; Sulfhydryl Compounds | 1981 |
Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding.
Topics: Base Sequence; Catalysis; Circular Dichroism; Citrobacter freundii; Cysteine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 1995 |
Examining the structural and chemical flexibility of the active site base, Lys-258, of Escherichia coli aspartate aminotransferase by replacement with unnatural amino acids.
Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Escherichia coli; Imines; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Structure-Activity Relationship; Titrimetry | 1995 |
Identification of essential lysyl and cysteinyl residues, and the amino acid sequence at the substrate-binding site of retinal oxidase.
Topics: Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Borohydrides; Chloromercuribenzoates; Cyanogen Bromide; Cysteine; Cytosol; Liver; Lysine; Male; Molecular Sequence Data; p-Chloromercuribenzoic Acid; Pyridoxal Phosphate; Rabbits; Retinal Dehydrogenase; Sequence Analysis; Trypsin | 1995 |
Tryptophanase from Escherichia coli: catalytic and spectral properties in water-organic solvents.
Topics: Alanine; Catalysis; Cysteine; Dimethylformamide; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methanol; Pyridoxal Phosphate; Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophanase; Water | 1994 |
Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Codon; Computer Graphics; Computer Simulation; Cysteine; Escherichia coli; Fluorescent Dyes; Indoles; Iodides; Kinetics; Ligands; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxazines; Phenylalanine; Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Tryptophan; Tryptophan Synthase | 1995 |
Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
Topics: Acetates; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Protein Conformation; Pyridoxal Phosphate; Regression Analysis; Salmonella typhimurium; Schiff Bases; Serine; Spectrometry, Fluorescence; Tryptophan | 1994 |
Reactivity of cysteinyl, arginyl, and lysyl residues of Escherichia coli phosphoenolpyruvate carboxykinase against group-specific chemical reagents.
Topics: Arginine; Binding Sites; Cysteine; Diacetyl; Escherichia coli; Glyoxal; Kinetics; Lysine; Phosphoenolpyruvate Carboxykinase (GTP); Pyrenes; Pyridoxal Phosphate; Sulfhydryl Reagents | 1993 |
The regulation of alanine and aspartate aminotransferase by different aminothiols and by vitamin B-6 derivatives.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Cyanates; Cysteine; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Stereoisomerism; Temperature | 1994 |
Mechanism for the desulfurization of L-cysteine catalyzed by the nifS gene product.
Topics: Allylglycine; Azotobacter vinelandii; Bacterial Proteins; Base Sequence; Catalysis; Cysteine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenesulfonates; Nitrogenase; Pyridoxal Phosphate; Sulfur | 1994 |
Replacement of active-site lysine-239 of thermostable aspartate aminotransferase by S-(2-aminoethyl)cysteine: properties of the mutant enzyme.
Topics: Aspartate Aminotransferases; Binding Sites; Cysteine; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Pyridoxal Phosphate; Temperature; Thermodynamics | 1994 |
Studies of the active-site lysyl residue of thermostable aspartate aminotransferase: combination of site-directed mutagenesis and chemical modification.
Topics: Aspartate Aminotransferases; Bacillus; Binding Sites; Circular Dichroism; Cysteine; Enzyme Stability; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Structure-Activity Relationship; Temperature | 1994 |
Intersubunit location of the active site of mammalian ornithine decarboxylase as determined by hybridization of site-directed mutants.
Topics: Alanine; Animals; Base Sequence; Binding Sites; Cysteine; Eflornithine; Lysine; Macromolecular Substances; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Hybridization; Ornithine Decarboxylase; Pyridoxal Phosphate; Structure-Activity Relationship | 1993 |
Escherichia coli contains a protein that is homologous in function and N-terminal sequence to the protein encoded by the nifS gene of Azotobacter vinelandii and that can participate in the synthesis of the Fe-S cluster of dihydroxy-acid dehydratase.
Topics: Alanine; Amino Acid Sequence; Azotobacter vinelandii; Bacterial Proteins; Chromatography, Gel; Chromatography, Ion Exchange; Cysteine; Disulfides; Escherichia coli; Genes, Bacterial; Haemophilus influenzae; Hydro-Lyases; Iron-Sulfur Proteins; Kinetics; Macromolecular Substances; Molecular Sequence Data; Naphthalenesulfonates; Pantetheine; Peptide Fragments; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Sulfhydryl Reagents | 1996 |
Reactivity of essential cysteine and lysine residues present at the catalytic domain of pig heart mitochondrial malate dehydrogenase.
Topics: Animals; Binding Sites; Cysteine; Dithionitrobenzoic Acid; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Mitochondria, Heart; NAD; o-Phthalaldehyde; Pyridoxal Phosphate; Swine | 1995 |
Substitutions of alanine for cysteine at a reactive thiol site and for lysine at a pyridoxal phosphate binding site of 1-aminocyclopropane-1-carboxylate deaminase.
Topics: Absorption; Alanine; Base Sequence; Binding Sites; Carbon-Carbon Lyases; Catalysis; Cysteine; Escherichia coli; Gene Expression Regulation, Enzymologic; Lyases; Lysine; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfhydryl Compounds; Valine | 1997 |
Modification of brain glutamate dehydrogenase isoproteins with pyridoxal 5'-phosphate.
Topics: Animals; Borohydrides; Brain; Cattle; Cysteine; Enzyme Inhibitors; Enzyme Reactivators; Glutamate Dehydrogenase; Isoenzymes; Lysine; Pyridoxal Phosphate | 1996 |
Mutation of cysteine 111 in Dopa decarboxylase leads to active site perturbation.
Topics: 5-Hydroxytryptophan; Alanine; Animals; Base Sequence; Binding Sites; Circular Dichroism; Cysteine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kidney; Kinetics; Levodopa; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Serine; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Swine | 1997 |
Some chemical properties and biological role of thiazolidine compounds.
Topics: Animals; Bacteria; Cysteamine; Cysteine; Female; Magnetic Resonance Spectroscopy; Male; Pregnancy; Pyridoxal Phosphate; Rats; Rats, Wistar; Stereoisomerism | 1998 |
High expression, purification, and properties of recombinant homocysteine alpha, gamma-lyase.
Topics: Animals; Carbon-Sulfur Lyases; Cardiovascular Diseases; Chromatography; Cloning, Molecular; Cysteine; Enzyme Stability; Escherichia coli; Homocysteine; Hydrogen-Ion Concentration; Hyperhomocysteinemia; Kinetics; Methionine; Protein Conformation; Protozoan Proteins; Pseudomonas putida; Pyridoxal Phosphate; Recombinant Proteins; Substrate Specificity; Temperature; Trichomonas vaginalis | 1998 |
The crystal structure of cystathionine gamma-synthase from Nicotiana tabacum reveals its substrate and reaction specificity.
Topics: Amino Acid Sequence; Binding Sites; Carbon-Oxygen Lyases; Catalysis; Crystallization; Crystallography, X-Ray; Cysteine; Escherichia coli; Homoserine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lyases; Models, Molecular; Molecular Sequence Data; Nicotiana; Plants, Toxic; Protein Structure, Secondary; Pyridoxal Phosphate; Substrate Specificity | 1999 |
Rhodobacter sphaeroides phosphoribulokinase: identification of lysine-165 as a catalytic residue and evaluation of the contributions of invariant basic amino acids to ribulose 5-phosphate binding.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Cysteine; Gluconates; Kinetics; Lysine; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphotransferases (Alcohol Group Acceptor); Pyridoxal Phosphate; Rhodobacter sphaeroides; Ribulosephosphates | 1999 |
Structure of a NifS homologue: X-ray structure analysis of CsdB, an Escherichia coli counterpart of mammalian selenocysteine lyase.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Lyases; Mice; Molecular Sequence Data; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Substrate Specificity | 2000 |
Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
Topics: Allylglycine; Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Dimerization; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Lyases; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Selenomethionine; Spectrophotometry; Sulfur; Thermotoga maritima; Transaminases | 2000 |
Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound.
Topics: Allosteric Regulation; Allosteric Site; Anions; Chlorides; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Dimerization; Hydrogen Bonding; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Salmonella typhimurium; Structure-Activity Relationship; Sulfates; Sulfides | 2000 |
Biochemical and molecular characterization of taurine:pyruvate aminotransferase from the anaerobe Bilophila wadsworthia.
Topics: beta-Alanine; Butyrates; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Deltaproteobacteria; Electrophoresis, Polyacrylamide Gel; Kinetics; Models, Chemical; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Oxaloacetic Acid; Pyridoxal Phosphate; Taurine; Time Factors; Transaminases; Ultraviolet Rays | 2000 |
Resonance Raman characterization of the heme cofactor in cystathionine beta-synthase. Identification of the Fe-S(Cys) vibration in the six-coordinate low-spin heme.
Topics: Binding, Competitive; Carbon Monoxide; Cystathionine beta-Synthase; Cysteine; Ferric Compounds; Ferrous Compounds; Heme; Homocysteine; Humans; Iron-Sulfur Proteins; Ligands; Mercuric Chloride; Molybdenum; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis, Raman | 2001 |
Inhibitors of advanced glycation end product-associated protein cross-linking.
Topics: Animals; Carbon Radioisotopes; Cattle; Cross-Linking Reagents; Crystallins; Cysteine; Electrophoresis, Polyacrylamide Gel; Fluorescence; Glucose; Glycation End Products, Advanced; Glycosylation; Lysine; Pyridoxal Phosphate; Sulfites; Tetroses; Thiamine Pyrophosphate | 2001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk.
Topics: Breast Neoplasms; Case-Control Studies; Catechol O-Methyltransferase; Cysteine; Estrogens, Catechol; Female; Folic Acid; Genotype; Homocysteine; Humans; Methylation; Micronutrients; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pyridoxal Phosphate; Risk Factors; S-Adenosylmethionine; Vitamin B 12 | 2001 |
The biosynthesis of ovothiol A (N-methyl-4-mercaptohistidine). Identification of S-(4'-L-histidyl)-L-cysteine sulfoxide as an intermediate and the products of the sulfoxide lyase reaction.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Crithidia fasciculata; Cysteine; Dipeptides; Dithiothreitol; Lyases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylhistidines; Methyltransferases; Pyridoxal Phosphate; Sulfoxides; Time Factors | 2001 |
Structure of external aldimine of Escherichia coli CsdB, an IscS/NifS homolog: implications for its specificity toward selenocysteine.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding Sites; Carbon-Sulfur Lyases; Crystallography, X-Ray; Cysteine; Escherichia coli; Lyases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Selenocysteine; Sequence Homology, Amino Acid; Substrate Specificity | 2002 |
Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme.
Topics: Amino Acid Motifs; Binding Sites; Catalysis; Catalytic Domain; Crystallization; Crystallography, X-Ray; Cystathionine beta-Synthase; Cysteine; Heme; Humans; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Pyridoxal Phosphate; Sequence Deletion | 2002 |
Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase.
Topics: Bacterial Proteins; Binding Sites; Cysteine; Cysteine Synthase; Genes, Bacterial; Isoenzymes; Molecular Structure; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrum Analysis; Transaminases | 2002 |
[Some relations between pyridoxal phosphate and the decarboxylation of cysteinesulfinic acid by various organs of the normal rat or of the vitamin B6-deficient rat].
Topics: Animals; Brain; Coenzymes; Cysteine; Decarboxylation; Liver; Pyridoxal Phosphate; Rats; Vitamin B 6; Vitamin B 6 Deficiency | 1955 |
[Role of transamination and pyridoxal phosphate in the enzymatic formation of hydrogen sulfide from cysteine by the rat liver under anaerobiosis].
Topics: Anaerobiosis; Animals; Biochemical Phenomena; Coenzymes; Cysteine; Hydrogen Sulfide; Liver; Pyridoxal Phosphate; Rats; Sulfides; Transaminases | 1956 |
[Study on the decarboxylation of L-cysteinesulfinic acid, L-cysteic acid, and L-glutamic acid by various organs of rabbits; influence of pyridoxal phosphate and thiol groups].
Topics: Animals; Aspartic Acid; Biochemical Phenomena; Coenzymes; Cysteic Acid; Cysteine; Decarboxylation; Glutamates; Glutamic Acid; Pyridoxal Phosphate; Rabbits; Sulfhydryl Compounds | 1956 |
A model system for cysteine desulphydrase action: pyridoxal phosphate-vanadium.
Topics: Coenzymes; Cystathionine gamma-Lyase; Cysteine; Hydro-Lyases; Models, Biological; Pyridoxal Phosphate; Vanadium | 1958 |
Interference with antibody neutralization by coenzyme and reducing agents.
Topics: Antibodies, Neutralizing; Antigen-Antibody Reactions; Coenzymes; Cysteine; Ligases; Mercaptoethylamines; Oxidoreductases; Pyridoxal Phosphate; Reducing Agents | 1963 |
THE REACTION OF THIOL AMINO ACIDS WITH PYRIDOXAL 5'-PHOSPHATE IN THE ABSENCE AND IN THE PRESENCE OF L-GLUTAMIC ACID.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Glutamic Acid; Penicillamine; Phosphates; Pyridoxal Phosphate; Research; Sulfhydryl Compounds | 1963 |
SUCCINIC ESTER AND AMIDE OF HOMOSERINE: SOME SPONTANEOUS AND ENZYMATIC REACTIONS.
Topics: Amides; Amino Acids; Cysteine; Escherichia coli; Homoserine; Methionine; Pyridoxal Phosphate; Research; Salmonella; Serine; Succinates | 1964 |
[NON-ENZYMIC SYNTHESIS OF CYSTEIC ACID FROM SOME BETA-SUBSTITUTED AMINO ACIDS, PYRUVATE, SULPHITE, AND COPPER IONS].
Topics: Amino Acid Substitution; Amino Acids; Catalysis; Chelating Agents; Chemical Phenomena; Chemistry; Copper; Cysteic Acid; Cysteine; Pyridoxal Phosphate; Pyruvates; Pyruvic Acid; Research; Serine; Sulfites; Sulfur | 1963 |
THE ROLE OF THYROID HORMONES IN TRANS-SULPHURATION. II. STUDIES ON THE MECHANISM OF INHIBITION OF CYSTATHIONASE BY IODOTHYRONINES.
Topics: Amino Acid Oxidoreductases; Amino Acids; Benzoates; Cyanides; Cystathionine gamma-Lyase; Cysteine; Dogs; Enzyme Inhibitors; Glutathione; Hydrazines; Liver; Pyridoxal Phosphate; Research; Thyroid Hormones; Thyroxine; Transferases; Triiodothyronine | 1964 |
PROPERTIES AND DISTRIBUTION OF MAMMALIAN L-CYSTEINE SULFINATE CARBOXY-LYASES.
Topics: Animals; Anura; Biochemistry; Brain; Carbon Isotopes; Carboxy-Lyases; Cats; Chromatography; Cysteine; Cystine; Dogs; Electrophoresis; Glutamates; Glutathione; Liver; Physiology, Comparative; Poultry; Pyridoxal Phosphate; Rats; Research; Species Specificity; Sulfonic Acids; Taurine | 1964 |
BREAKDOWN OF S-AMINOETHYLCYSTEINE BY PYRIDOXAL PHOSPHATE.
Topics: Aminohydrolases; Ammonia; Cysteine; Mercaptoethylamines; Pyridoxal Phosphate; Pyruvates; Research; Spectrophotometry; Sulfhydryl Compounds | 1964 |
CATALYTIC PROPERTIES OF TRYPTOPHANASE, A MULTIFUNCTIONAL PYRIDOXAL PHOSPHATE ENZYME.
Topics: Aminohydrolases; Ammonia; Animals; Catalysis; Cattle; Cysteine; Electrophoresis; Escherichia coli; Indoles; Leuconostoc; Manometry; Multifunctional Enzymes; Mutation; Potassium; Pyridoxal Phosphate; Pyruvates; Research; Serine; Serum Albumin; Serum Albumin, Bovine; Tryptophan | 1964 |
THE NUTRITION OF VIBRIO COSTICOLUS. II. CYST(E)INE UTILIZATION.
Topics: Ammonia; Citric Acid Cycle; Cysteine; Cysts; Fluoroacetates; Hydrogen; Proteins; Pyridoxal Phosphate; Pyruvates; Research; Sodium Chloride; Sulfides; Vibrio | 1964 |
CYSTATHIONINE CLEAVAGE ENZYMES OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Homocysteine; Iodoacetates; L-Lactate Dehydrogenase; Maleates; Neurospora; Pyridoxal Phosphate; Pyruvates; Research; Serine; Sulfhydryl Compounds | 1964 |
PURIFICATION AND PROPERTIES OF THE CYSTATHIONINE GAMMA-CLEAVAGE ENZYME OF NEUROSPORA.
Topics: Amino Acid Oxidoreductases; Amino Acids; Butyrates; Cystathionine; Cysteine; Cystine; Enzyme Inhibitors; Ethers; Gamma Rays; Neurospora; Pyridoxal Phosphate; Research; Serine; Sulfides | 1964 |
AN INTERMEDIATE TRAPPED BY MALEIMIDES IN A PYRIDOXAL-PHOSPHATE POTENTIATED ENZYMATIC ELIMINATION REACTION.
Topics: Amino Acids; Butyrates; Carbon Isotopes; Chromatography; Cysteine; Ethylmaleimide; Homocysteine; Keto Acids; Ligases; Lyases; Maleimides; Neurospora; Phosphates; Pyridoxal Phosphate; Pyrroles; Pyruvates; Research; Threonine | 1964 |
[ENZYMATIC BETA SUBSTITUTION OF PHOSPHOSERINE AND CYSTEINE BY SULFITE. SOME REMARKS ON THE MECHANISM OF BETA SUBSTITUTION IN THE PRESENCE OF PYRIDOXAL PHOSPHATE ENZYMES].
Topics: Cysteine; Extraembryonic Membranes; Hydro-Lyases; Lyases; Phosphates; Phosphoserine; Pyridoxal Phosphate; Serine; Sulfites; Sulfonic Acids; Sulfur Isotopes; Vitelline Membrane | 1964 |
ENZYMATIC DESULFINATION OF CYSTEINE SULFINIC ACID.
Topics: Alanine; Alcaligenes; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carboxy-Lyases; Cysteine; Keto Acids; Ketoglutaric Acids; Pyridoxal Phosphate; Research; Sulfites | 1964 |
INHIBITION OF PLASMA MONOAMINE OXIDASE BY CYSTEAMINE.
Topics: Amines; Animals; Cattle; Chemical Phenomena; Chemistry; Cysteamine; Cysteine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridoxal Phosphate; Research; Spermine | 1965 |
CLEAVAGE OF S-(1,2-DICHLOROVINYL)-L-CYSTEINE BY ESCHERICHIA COLI B.
Topics: Ammonia; Carbon Isotopes; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chlorides; Cysteine; Escherichia coli; Hydroxylamines; Metabolism; Pyridoxal Phosphate; Pyruvates; Research; Sulfur Isotopes | 1965 |
Pyridoxal phosphate as the coenzyme of the mammalian decarboxylase for L-cysteine sulphinic and L-cysteic acids.
Topics: Animals; Carboxy-Lyases; Coenzymes; Cysteic Acid; Cysteine; Lyases; Mammals; Pyridoxal Phosphate | 1955 |
[Influence of thyroid hormones on the desulfuration of cysteine by rat liver. Comparison of the behavior of the desulfuration with that of other enzymatic reactions requiring pyridoxal phosphate].
Topics: Cell Physiological Phenomena; Coenzymes; Cysteine; Hormones; Liver; Pyridoxal Phosphate; Thyroid Gland; Thyroid Hormones | 1960 |
Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate.
Topics: Animals; Aspartic Acid; Carboxy-Lyases; Catalysis; Cattle; Cystathionine gamma-Lyase; Cysteine; Decarboxylation; Kinetics; Neurotransmitter Agents; Oxaloacetates; Pyridoxal Phosphate; Pyruvic Acid; Rabbits; Spectrophotometry; Treponema | 2003 |
Plasma taurine and cysteine levels following an oral methionine load: relationship with coronary heart disease.
Topics: Adult; Case-Control Studies; Coronary Disease; Cysteine; Europe; Fasting; Humans; India; Male; Methionine; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Taurine | 2004 |
Kinetic and structural characterization of Slr0077/SufS, the essential cysteine desulfurase from Synechocystis sp. PCC 6803.
Topics: Amino Acid Substitution; Binding Sites; Carbon-Sulfur Lyases; Crystallography, X-Ray; Cyanobacteria; Cysteine; Disulfides; Gene Expression; Kinetics; Models, Molecular; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Spectrum Analysis; Time Factors | 2004 |
Mechanism of cysteine desulfurase Slr0387 from Synechocystis sp. PCC 6803: kinetic analysis of cleavage of the persulfide intermediate by chemical reductants.
Topics: Carbon-Sulfur Lyases; Catalysis; Cyanobacteria; Cysteine; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Phosphines; Pyridoxal Phosphate; Reducing Agents; Spectrum Analysis; Sulfhydryl Compounds; Sulfides; Temperature | 2004 |
Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration.
Topics: Aldehyde Oxidase; Arabidopsis; Arabidopsis Proteins; Bacterial Proteins; Binding Sites; Catalysis; Coenzymes; Cysteine; Cytosol; Fluorescent Dyes; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lyases; Lysine; Metalloproteins; Molybdenum; Molybdenum Cofactors; Mutagenesis, Site-Directed; Naphthalenesulfonates; Pichia; Plant Proteins; Protein Binding; Protein Structure, Tertiary; Pteridines; Pyridoxal Phosphate; Selenocysteine; Spectrophotometry; Substrate Specificity; Sulfides; Sulfurtransferases; Xanthine Dehydrogenase | 2005 |
Effect of a swim training on homocysteine and cysteine levels in rats.
Topics: Animals; Cystathionine beta-Synthase; Cysteine; Glutathione; Homocysteine; Liver; Male; Physical Conditioning, Animal; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Swimming; Taurine | 2005 |
Isolation and characterization of a D-cysteine desulfhydrase protein from Arabidopsis thaliana.
Topics: Amino Acids, Cyclic; Arabidopsis; Binding Sites; Cell Nucleus; Cystathionine gamma-Lyase; Cysteine; Escherichia coli; Green Fluorescent Proteins; Mitochondria; Phylogeny; Pyridoxal Phosphate; Pyruvic Acid; Recombinant Proteins; RNA, Plant; Subcellular Fractions | 2005 |
Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy.
Topics: Acetyltransferases; Amino Acid Sequence; Bacteria; Binding Sites; Cysteine; Cysteine Synthase; Molecular Sequence Data; Pyridoxal Phosphate; Serine O-Acetyltransferase; Spectrometry, Fluorescence | 2005 |
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.
Topics: Antioxidants; Bacillus subtilis; Binding Sites; Carbon-Nitrogen Lyases; Chromatography; Chromatography, Gel; Chromatography, High Pressure Liquid; Cloning, Molecular; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Glutaminase; Glutamine; Immunochemistry; Isoxazoles; Kinetics; Mass Spectrometry; Models, Chemical; Organophosphates; Oxidoreductases; Pentosephosphates; Protein Structure, Tertiary; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Threonine; Time Factors; Ultraviolet Rays; Vitamin B 6 | 2005 |
Molecular basis of cysteine biosynthesis in plants: structural and functional analysis of O-acetylserine sulfhydrylase from Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Asparagine; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Cytosol; Databases, Protein; Glutamine; Kinetics; Ligands; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Threonine | 2005 |
Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: an inhibition kinetic approach combined with the analysis of the homology structural model.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acid Transport Systems, Basic; Animals; Binding Sites; Biological Transport; Citrulline; Cysteine; Lysine; Mutation; Ornithine; Protein Conformation; Pyridoxal Phosphate; Rats; Structural Homology, Protein; Sulfhydryl Reagents | 2005 |
New insights into the reaction mechanism catalyzed by the glutamate racemase enzyme: pH titration curves and classical molecular dynamics simulations.
Topics: Amino Acid Isomerases; Amino Acids; Bacteria; Biophysics; Catalysis; Chemistry, Physical; Computer Simulation; Cysteine; Hydrogen; Hydrogen-Ion Concentration; Models, Chemical; Models, Statistical; Protein Conformation; Pyridoxal Phosphate | 2007 |
Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain; Busulfan; Cysteine; Kidney; Liver; Lyases; Pyridoxal Phosphate; Rats | 2008 |
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol.
Topics: Alcohol Drinking; Animals; Cysteine; Ethanol; Methionine; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; S-Adenosylhomocysteine; S-Adenosylmethionine; Taurine | 2009 |
Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria.
Topics: Binding Sites; Biocatalysis; Carbon-Oxygen Lyases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Cysteine Synthase; Kinetics; Models, Molecular; Mutation; Mycobacterium tuberculosis; Protein Structure, Tertiary; Pyridoxal Phosphate; Spectrophotometry; Substrate Specificity | 2008 |
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production.
Topics: Amino Acid Substitution; Ammonia; Butyrates; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Humans; Hydrogen Sulfide; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Pyridoxal Phosphate; Pyruvic Acid | 2010 |
L-cysteine stimulates hydrogen sulfide synthesis in myocardium associated with attenuation of ischemia-reperfusion injury.
Topics: Alkynes; Analysis of Variance; Animals; Cysteine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Glycine; Hydrogen Sulfide; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Vitamin B Complex | 2010 |
Plasma homocysteine and cysteine and risk of breast cancer in women.
Topics: Breast Neoplasms; Case-Control Studies; Cysteine; Female; Folic Acid; Homocysteine; Humans; Middle Aged; Prospective Studies; Pyridoxal Phosphate; Vitamin B 12 | 2010 |
Pyridoxal 5'-phosphate in cerebrospinal fluid; factors affecting concentration.
Topics: Adolescent; Adult; Biopterins; Child; Child, Preschool; Cysteine; Epilepsy; False Positive Reactions; Female; Free Radicals; Humans; Infant; Infant, Newborn; Levodopa; Male; Metabolism, Inborn Errors; Middle Aged; Nervous System Diseases; Oxygen; Pyridoxal Phosphate; Reference Values; Reproducibility of Results; Sulfites; Tetrahydrofolates | 2011 |
Cobalt cystathionine β-synthase: a cobalt-substituted heme protein with a unique thiolate ligation motif.
Topics: Circular Dichroism; Cloning, Molecular; Cobalt; Coordination Complexes; Cystathionine beta-Synthase; Cysteine; Escherichia coli; Heme; Hemeproteins; Histidine; Humans; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry, Atomic | 2011 |
A novel mechanism of sulfur transfer catalyzed by O-acetylhomoserine sulfhydrylase in the methionine-biosynthetic pathway of Wolinella succinogenes.
Topics: Biosynthetic Pathways; Carbon-Oxygen Lyases; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cystathionine gamma-Lyase; Cysteine; Methionine; Protein Conformation; Protein Folding; Pyridoxal Phosphate; Structural Homology, Protein; Sulfur; Wolinella | 2011 |
Mutational analysis of Sep-tRNA:Cys-tRNA synthase reveals critical residues for tRNA-dependent cysteine formation.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Binding Sites; Catalytic Domain; Conserved Sequence; Cysteine; DNA Mutational Analysis; Methanococcaceae; Models, Molecular; Protein Conformation; Pyridoxal Phosphate; RNA, Transfer, Amino Acyl | 2012 |
Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation.
Topics: Amino Acid Sequence; Binding Sites; Carbon-Sulfur Lyases; Catalysis; Crystallography, X-Ray; Cysteine; DNA; Enzyme Activation; Epigenesis, Genetic; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Sequence Alignment; Streptomyces lividans | 2012 |
Structural insights into catalysis by βC-S lyase from Streptococcus anginosus.
Topics: Absorption; Amino Acid Sequence; Bacterial Proteins; Catalysis; Cystathionine gamma-Lyase; Cysteine; Hydrogen Sulfide; Lyases; Models, Molecular; Molecular Sequence Data; Protein Conformation; Pyridoxal Phosphate; Sequence Alignment; Streptococcus anginosus | 2012 |
Analysis of the sulfur-regulated control of the cystathionine γ-lyase gene of Neurospora crassa.
Topics: Base Sequence; Binding Sites; Cloning, Molecular; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Electrophoretic Mobility Shift Assay; Escherichia coli; Fungal Proteins; Gene Expression Regulation, Fungal; Gene Regulatory Networks; Molecular Sequence Data; Mutation; Neurospora crassa; Promoter Regions, Genetic; Protein Binding; Pyridoxal Phosphate; Recombinant Proteins; RNA, Messenger; Sulfur; Vesicular Transport Proteins | 2012 |
Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.
Topics: Adenocarcinoma; Adult; Case-Control Studies; Colorectal Neoplasms; Cysteine; DNA Methylation; DNA, Neoplasm; Female; Health Surveys; Homocysteine; Humans; Leukocytes, Mononuclear; Logistic Models; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Pyridoxal Phosphate; Risk Factors | 2013 |
Increase or decrease hydrogen sulfide exert opposite lipolysis, but reduce global insulin resistance in high fatty diet induced obese mice.
Topics: Adipocytes; Alkynes; Animals; Blood Glucose; Carrier Proteins; Cystathionine gamma-Lyase; Cysteine; Diet, High-Fat; Enzyme Inhibitors; Glycerol; Glycine; Hydrogen Sulfide; Insulin; Insulin Resistance; Isoproterenol; Lipolysis; Mice; Morpholines; Obesity; Organothiophosphorus Compounds; Perilipin-1; Phosphoproteins; Primary Cell Culture; Pyridoxal Phosphate; Rats; Sterol Esterase | 2013 |
High homocysteine is associated with increased risk of colorectal cancer independently of oxidative stress and antioxidant capacities.
Topics: Adult; Aged; Antioxidants; Blood Pressure; Body Mass Index; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Glutathione Peroxidase; Glutathione Transferase; Healthy Volunteers; Homocysteine; Humans; Linear Models; Male; Middle Aged; Oxidative Stress; Pyridoxal Phosphate; Risk Factors; Serum Albumin; Superoxide Dismutase | 2014 |
Sulfur mobilization for Fe-S cluster assembly by the essential SUF pathway in the Plasmodium falciparum apicoplast and its inhibition.
Topics: Antimetabolites; Apicoplasts; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cycloserine; Cysteine; Inhibitory Concentration 50; Iron-Sulfur Proteins; Models, Molecular; Models, Structural; Mutagenesis; Plasmodium falciparum; Protein Interaction Mapping; Protozoan Proteins; Pyridoxal Phosphate; Sulfides; Sulfur | 2014 |
Vitamin B-6 restriction reduces the production of hydrogen sulfide and its biomarkers by the transsulfuration pathway in cultured human hepatoma cells.
Topics: Alanine; Biomarkers; Carcinoma, Hepatocellular; Cysteine; Hep G2 Cells; Homocysteine; Humans; Hydrogen Sulfide; Linear Models; Liver Neoplasms; Pyridoxal Phosphate; Sulfides; Vitamin B 6; Vitamin B 6 Deficiency | 2014 |
Pre-steady-state kinetic and structural analysis of interaction of methionine γ-lyase from Citrobacter freundii with inhibitors.
Topics: Alanine; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Citrobacter freundii; Crystallography, X-Ray; Cycloserine; Cysteine; Enzyme Inhibitors; Escherichia coli; Gene Expression; Glycine; Imines; Kinetics; Models, Chemical; Pyridoxal Phosphate; Recombinant Proteins; Thermodynamics; Valine | 2015 |
IscS from Archaeoglobus fulgidus has no desulfurase activity but may provide a cysteine ligand for [Fe2S2] cluster assembly.
Topics: Amino Acid Sequence; Archaeal Proteins; Archaeoglobus fulgidus; Carbon-Sulfur Lyases; Crystallography, X-Ray; Cysteine; Iron; Iron-Sulfur Proteins; Ligands; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Mutation, Missense; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Sequence Homology, Amino Acid; Sulfides | 2015 |
Deletion of the Proposed Iron Chaperones IscA/SufA Results in Accumulation of a Red Intermediate Cysteine Desulfurase IscS in Escherichia coli.
Topics: Alanine; Carbon-Sulfur Lyases; Carrier Proteins; Cysteine; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Iron; Iron-Sulfur Proteins; Molecular Chaperones; Mutagenesis, Site-Directed; Oxidation-Reduction; Pyridoxal Phosphate; Recombinant Proteins; Sulfides | 2015 |
Quantification of homocysteine and cysteine by derivatization with pyridoxal 5'-phosphate and hydrophilic interaction liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Cysteine; Homocysteine; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Pyridoxal Phosphate; Reproducibility of Results | 2016 |
Differences in PLP-Dependent Cysteinyl Processing Lead to Diverse S-Functionalization of Lincosamide Antibiotics.
Topics: Anti-Bacterial Agents; Catalysis; Cysteine; Lincosamides; Pyridoxal Phosphate | 2016 |
Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU.
Topics: Alanine; Bacillus subtilis; Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Deuterium Exchange Measurement; Frataxin; Iron-Binding Proteins; Iron-Sulfur Proteins; Models, Molecular; Multigene Family; Protein Binding; Protein Conformation; Protein Multimerization; Pyridoxal Phosphate; Sulfides | 2016 |
Characterization of C-S lyase from Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 and its potential role in food flavour applications.
Topics: Algorithms; Amino Acid Sequence; Bacterial Proteins; Carbon-Sulfur Lyases; Cystathionine; Cysteine; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Flavoring Agents; Hydrogen-Ion Concentration; Kinetics; Lactobacillus delbrueckii; Lyases; Models, Molecular; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Sulfur Compounds | 2017 |
Structural Snapshots of an Engineered Cystathionine-γ-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Topics: Amino Acid Substitution; Arginine; Biocatalysis; Carbon-Sulfur Lyases; Catalytic Domain; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Enzyme Stability; Humans; Hydrogen Bonding; Hydrolysis; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Engineering; Pyridoxal Phosphate; Recombinant Proteins; Selenomethionine; Substrate Specificity | 2017 |
A two-step evolutionary process establishes a non-native vitamin B6 pathway in Bacillus subtilis.
Topics: Bacillus subtilis; Cysteine; Escherichia coli; Glucosamine; Pentosephosphates; Proteins; Pyridoxal Phosphate; Vitamin B 6 | 2018 |
Crystal Structures of Cystathionine β-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.
Topics: Catalysis; Cystathionine beta-Synthase; Cysteine; Heme; Humans; Kinetics; Models, Molecular; Oxidation-Reduction; Pyridoxal Phosphate; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2018 |
One-carbon metabolite ratios as functional B-vitamin markers and in relation to colorectal cancer risk.
Topics: Betaine; Biomarkers, Tumor; Carbon; Case-Control Studies; Colorectal Neoplasms; Creatinine; Cysteine; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Vitamin B 12; Vitamin B Complex | 2019 |
Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase.
Topics: Amino Acid Sequence; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Histidine Decarboxylase; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Conformation; Pyridoxal Phosphate; Sequence Homology | 2018 |
Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B
Topics: Animals; Catalysis; Cysteine; Erythrocytes; Hemolysis; Hydrogen Sulfide; Hydrolysis; Iron; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridoxal Phosphate; Spectrophotometry, Ultraviolet; Vitamin B 6 | 2019 |
Structural and Kinetic Insight into the Biosynthesis of H
Topics: Alanine; Bacterial Proteins; Cystathionine beta-Synthase; Cysteine; Cysteine Synthase; Fusobacterium nucleatum; Humans; Hydro-Lyases; Hydrogen Sulfide; Kinetics; Multienzyme Complexes; Protein Conformation; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfides; Yeasts | 2019 |
Mechanism of activation of the human cysteine desulfurase complex by frataxin.
Topics: Allosteric Regulation; Carbon-Sulfur Lyases; Catalytic Domain; Cysteine; Frataxin; Humans; Iron-Binding Proteins; Iron-Sulfur Proteins; Kinetics; Multiprotein Complexes; Mutation; Protein Binding; Pyridoxal Phosphate; Sulfides; Sulfur | 2019 |
Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System.
Topics: Bacterial Proteins; Carbon-Sulfur Lyases; Catalytic Domain; Crystallography, X-Ray; Cysteine; DNA; Iron-Sulfur Proteins; Molecular Dynamics Simulation; Phosphorothioate Oligonucleotides; Pyridoxal Phosphate; Sulfur; Vibrio | 2020 |
2-(3-Hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic Acid, Novel Metabolite of Pyridoxal 5'-Phosphate and Cysteine Is Present in Human Plasma-Chromatographic Investigations.
Topics: Cysteine; Gas Chromatography-Mass Spectrometry; Humans; Plasma; Pyridoxal Phosphate; Thiazolidines | 2020 |
The Biosynthetic Pathway of Ergothioneine in Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes).
Topics: Agaricales; Antioxidants; Biosynthetic Pathways; Cysteine; Ergothioneine; Escherichia coli; Flammulina; Gene Expression; Histidine; Pyridoxal Phosphate | 2020 |
Structure and substrate specificity determinants of the taurine biosynthetic enzyme cysteine sulphinic acid decarboxylase.
Topics: Amino Acid Sequence; Animals; Carboxy-Lyases; Catalytic Domain; Cysteine; Mice; Protein Binding; Pyridoxal Phosphate; Substrate Specificity; Taurine | 2021 |
Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Topics: Bayes Theorem; Biomarkers; Carcinoma, Renal Cell; Case-Control Studies; Cysteine; Homocysteine; Humans; Kidney Neoplasms; Prospective Studies; Pyridoxal Phosphate; Vitamin B 6 | 2022 |
Topics: Animals; Cryoelectron Microscopy; Cystathionine beta-Synthase; Cysteine; Methionine; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Pyridoxal Phosphate; S-Adenosylmethionine; Sulfur | 2022 |
MitoNEET's Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme.
Topics: Cysteine; Glutamates; Histidine; Hydrogen; Iron; Iron-Sulfur Proteins; Ketoglutaric Acids; Lysine; Mitochondrial Proteins; Pyridoxal Phosphate; Sulfur; Transaminases | 2022 |
Enzyme-independent catabolism of cysteine with pyridoxal-5'-phosphate.
Topics: Cysteine; Hydrogen Sulfide; Phosphates; Pyridoxal Phosphate; Thiazolidines | 2023 |
Simultaneous determination of 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid and main plasma aminothiols by HPLC-UV based method.
Topics: Chromatography, High Pressure Liquid; Cysteine; Glutathione; Pyridoxal Phosphate; Reproducibility of Results; Sulfhydryl Compounds; Thiazolidines | 2023 |