pyridoxal phosphate has been researched along with arginine in 95 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (47.37) | 18.7374 |
| 1990's | 20 (21.05) | 18.2507 |
| 2000's | 14 (14.74) | 29.6817 |
| 2010's | 12 (12.63) | 24.3611 |
| 2020's | 4 (4.21) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Roberts, J; Rosenfeld, HJ | 1 |
| Hemmilä, IA; Mäntsälä, PI | 1 |
| Christie, EA; Farley, JR; Segel, IH; Seubert, PA | 1 |
| Kazarinoff, MN; Snell, EE | 2 |
| Chirikjian, JG; Lee, YH | 1 |
| Bellini, T; Dallocchio, F; Rippa, M; Signorini, M | 1 |
| McCurry, SD; Paech, C; Pierce, J; Tolbert, NE | 1 |
| Chatagner, F; Pierre, Y | 1 |
| Nakagawa, H; Ogura, N; Sato, T; Sato, Y; Shiraishi, N | 1 |
| Cooperman, BS; Mitchell, LL | 1 |
| Dekker, EE; Mukherjee, JJ | 1 |
| Esaki, N; Futaki, S; Manning, JM; Nishimura, K; Soda, K; Tanizawa, K; Yoshimura, T | 1 |
| Cuchillo, CM; Parés, X; Richardson, RM | 1 |
| Boyen, A; Crabeel, M; Glansdorff, N; Heimberg, H | 1 |
| Ahmed, SA; Kawasaki, H; Miles, EW; Morita, H; Nagata, S | 1 |
| Kojiro, CL; Lewis, SD; Marceau, M; Shafer, JA | 1 |
| Balasundaram, D; Tyagi, AK | 1 |
| Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM | 1 |
| Müller, RE; Traish, AM | 1 |
| Inoue, Y; Kagamiyama, H; Kuramitsu, S; Morino, Y; Tanase, S | 1 |
| Modak, MJ; Pandey, VN | 1 |
| Kaminski, M; McDonagh, J | 1 |
| Fischer, EH; Sabo, DL | 1 |
| Kremzner, LT; Sturman, JA | 1 |
| Archard, LC; Williamson, JD | 1 |
| Groman, E; Huang, YZ; Snell, EE; Watanabe, T | 1 |
| Morris, DR; Wu, WH | 2 |
| Soda, K | 1 |
| Blethen, SL; Boeker, EA; Snell, EE | 1 |
| Boeker, EA; Snell, EE | 1 |
| Forsyth, GW; Jones, EE; Theil, EC; Vogel, HJ | 1 |
| Boeker, EA; Fischer, EH; Snell, EE | 1 |
| Snell, EE | 1 |
| Angelino, N; Korytnyk, W; Lachmann, B | 1 |
| Ames, BN; FerroLuzzi-Ames, G; Shifrin, S | 1 |
| Morino, Y; Snell, EE | 1 |
| Ogata, K; Yorifuji, T | 1 |
| Misono, H; Soda, K; Yorifuji, T | 1 |
| Ogata, K; Soda, K; Yorifuji, T | 1 |
| Osumi, T; Soda, K | 1 |
| Ikawa, M | 1 |
| Buc, H; Vandenbunder, B | 1 |
| Fong, WF; Ng, SF; Yao, KM | 1 |
| Kolattukudy, PE; Poulose, AJ; Rogers, L | 1 |
| Gracy, RW; Lu, HS; Talent, JM | 1 |
| Misono, H; Soda, K; Tanizawa, K; Toyama, S; Yasuda, M | 1 |
| Tunnicliff, G | 1 |
| Hori, K; Kanda, M; Kurotsu, T; Saito, Y; Takechi, M | 1 |
| Grishin, NV; Kinch, LN; Osterman, AL; Phillips, MA | 1 |
| Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Silva, R | 1 |
| Christen, P; Hohenester, E; Jansonius, JN; Karpeisky, MY; Khomutov, AR; Khomutov, RM; Marković-Housley, Z; Sandmeier, E; Schirmer, T | 1 |
| Brooks, HB; Osterman, AL; Phillips, MA; Rizo, J | 1 |
| Contestabile, R; Grimm, B; Hennig, M; Jansonius, JN; John, RA | 1 |
| Cardemil, E; Chávez, R; Krautwurst, H | 1 |
| Brünger, AT; Shah, SA; Shen, BW | 1 |
| Preiss, J; Sheng, J | 1 |
| Hao, S; Lu, J; Zhang, H; Zhang, J | 1 |
| Morollo, AA; Petsko, GA; Ringe, D | 1 |
| Sun, S; Toney, MD | 1 |
| Ostrovtsova, SA | 1 |
| Picone, R; Stoughton, DM; Vann, WF; Zapata, G | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Miyahara, I; Mizuguchi, H; Okada, K | 1 |
| di Salvo, ML; Ko, TP; Musayev, FN; Raboni, S; Safo, MK; Schirch, V | 1 |
| BONAVITA, V; SCARDI, V | 1 |
| ALBRECHT, AM; VOGEL, HJ | 1 |
| Connolly, SA; Francklyn, CS; Musier-Forsyth, K; Rosen, AE | 1 |
| Nishio, I; Tsuda, K | 1 |
| Griessler, R; Nidetzky, B; Psik, B; Schwarz, A | 1 |
| Chen, HY; Lima, S; Phillips, RS; Shim, D; Sundararaju, B; Tavakoli, K | 1 |
| Creuzenet, C; Obhi, RK | 1 |
| Fujitani, Y; Ishihara, K; Ito, K; Nakajima, N; Oikawa, T; Sugimoto, M | 1 |
| Antson, AA; Demidkina, TV; Kulikova, VV; Matković-Calogović, D; Milić, D; Sinitzina, NI | 1 |
| Capitani, G; Christen, P; Giannattasio, S; Marra, E; Vacca, RA | 1 |
| Ko, TP; Lee, CY; Wang, NC | 1 |
| Arakawa, N; Eggeling, L; Freudl, R; Lausberg, F; Matsui, D; Oikawa, T; Osumi, S; Stäbler, N | 1 |
| Kuzuyama, T; Miyagawa, T; Nishiyama, M; Ouchi, T; Tomita, T | 1 |
| Hegg, CC; Jia, C | 1 |
| Ambili, M; Jala, VR; Prakash, V; Rao, NA; Savithri, HS | 1 |
| Bröcker, MJ; Hammond, G; Itoh, Y; Sekine, S; Söll, D; Suetsugu, S; Yokoyama, S | 1 |
| Busnardo, C; Correa, FM; Cruz, JC; Ferreira-Junior, NC; Machado, BH; Resstel, LB | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Blankenfeldt, W; Nowicki, C; Wen, J | 1 |
| Han, L; Moran, GR; Schwabacher, AW; Silvaggi, NR | 1 |
| Alkhalaf, LM; Du, YL; Eltis, LD; He, HY; Kuatsjah, E; Ryan, KS; Singh, R | 1 |
| Stone, E; Yan, W; Zhang, YJ | 1 |
| Bharath, SR; Deka, G; Murthy, MRN; Savithri, HS | 1 |
| Du, YL; Eltis, LD; Hedges, JB; Kuatsjah, E; Ryan, KS | 1 |
| Boussery, K; De Spiegeleer, B; Peeters, E; Remon, JP; Van Tongelen, I; Vanhoorne, V; Vervaet, C; Wynendaele, E | 1 |
| Bouchereau, J; Schiff, M | 1 |
| Bellezza, I; Borri Voltattorni, C; Cellini, B; Desbats, MA; Montioli, R; Salviati, L | 1 |
| Aarsand, AK; Aguilera, P; Brunet, M; Deulofeu, R; García-Villoria, J; Gómez-Gómez, À; Pozo, OJ; Sandberg, S; To-Figueras, J; Wijngaard, R | 1 |
| Melkonian, TR; Silvaggi, NR; Vuksanovic, N | 1 |
5 review(s) available for pyridoxal phosphate and arginine
| Article | Year |
|---|---|
The role of lysyl, arginyl, and sulfhydryl residues in estrogen receptor activation, 4S to 5S dimerization, and conversion of receptor from a state with low affinity into a state with higher affinity for estrogen.
Topics: Alkylation; Animals; Arginine; Cell Nucleus; Cyclohexanones; Dose-Response Relationship, Drug; Hydroxymercuribenzoates; Kinetics; Lysine; Mersalyl; Molecular Weight; Polymers; Protein Conformation; Pyridoxal Phosphate; Receptors, Estrogen; Structure-Activity Relationship; Sulfhydryl Compounds | 1986 |
[Amino acid racemases (author's transl)].
Topics: Adenosine Triphosphate; Alanine; Amino Acid Isomerases; Arginine; Chemical Phenomena; Chemistry; Coenzymes; Flavin-Adenine Dinucleotide; Glutamine; Hydrogen-Ion Concentration; Hydroxyproline; Magnetic Resonance Spectroscopy; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry | 1974 |
Analogs of pyridoxal or pyridoxal phosphate: relation of structure to binding with apoenzymes and to catalytic activity.
Topics: Apoproteins; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Hydrolases; L-Serine Dehydratase; Models, Biological; Organophosphorus Compounds; Phosphorylases; Picolines; Protein Binding; Protein Conformation; Pyridines; Pyridoxal; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Pyruvates; Structure-Activity Relationship; Transaminases; Tryptophan | 1970 |
Inherited Disorders of Lysine Metabolism: A Review.
Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Amino Acid Metabolism, Inborn Errors; Arginine; Brain; Brain Diseases, Metabolic; Brain Diseases, Metabolic, Inborn; Carnitine; Epilepsy; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Metabolic Diseases; Pyridoxal Phosphate; Pyridoxine | 2020 |
Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects.
Topics: Arginine; Choroid; Chromosomes, Human, Pair 10; Coenzymes; Diet; Gene Expression; Gyrate Atrophy; Humans; Models, Molecular; Mutation; Ornithine; Ornithine-Oxo-Acid Transaminase; Protein Multimerization; Protein Structure, Secondary; Pyridoxal Phosphate; Retina; Vitamin B 6 | 2021 |
90 other study(ies) available for pyridoxal phosphate and arginine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Arginine decarboxylase from a Pseudomonas species.
Topics: Aminooxyacetic Acid; Ammonium Sulfate; Arginine; Carboxy-Lyases; Cell-Free System; Chemical Fractionation; Chloromercuribenzoates; Chromatography, Gel; Edetic Acid; Hydrogen-Ion Concentration; Magnesium; Polyamines; Pseudomonas; Pyridoxal Phosphate; Stereoisomerism | 1976 |
Inactivation of glutamate dehydrogenase and glutamate synthase from Bacillus megaterium by phenylglyoxal, butane-2,3-dione and pyridoxal 5'-phosphate.
Topics: Aldehydes; Arginine; Bacillus megaterium; Binding Sites; Butanones; Diacetyl; Glutamate Dehydrogenase; Glutamate Synthase; Glyoxal; Kinetics; NADP; Pyridoxal Phosphate; Transaminases | 1978 |
Adenosine triphosphate sulfurylase from Penicillium chrysogenum. Evidence for essential arginine, histidine, and tyrosine residues.
Topics: Arginine; Binding Sites; Dithionitrobenzoic Acid; Histidine; Kinetics; Nucleotidyltransferases; Penicillium; Penicillium chrysogenum; Pyridoxal; Pyridoxal Phosphate; Sulfate Adenylyltransferase; Tyrosine | 1979 |
Essential arginine residues in tryptophanase from Escherichia coli.
Topics: Arginine; Binding Sites; Escherichia coli; Kinetics; Lyases; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Substrate Specificity; Tryptophanase | 1977 |
Sequence-specific endonuclease Bgl I. Modification of lysine and arginine residues of the homogeneous enzyme.
Topics: Arginine; Bacillus; Deoxyribonucleases; Diacetyl; Endonucleases; Kinetics; Lysine; Magnesium; Molecular Weight; Pyridoxal Phosphate | 1979 |
The active site of 6-phosphogluconate dehydrogenase. A phosphate binding site and its surroundings.
Topics: Arginine; Arsenates; Binding Sites; Candida; Diacetyl; Dithionitrobenzoic Acid; Histidine; Lysine; Phosphates; Phosphogluconate Dehydrogenase; Pyridoxal Phosphate; Sulfhydryl Compounds | 1978 |
Active site of ribulose 1,5-bisphosphate carboxylase/oxygenase.
Topics: Arginine; Bicarbonates; Binding Sites; Carboxy-Lyases; Kinetics; Lysine; Magnesium; Pyridoxal Phosphate; Ribulose-Bisphosphate Carboxylase | 1978 |
D-Serine dehydratase from Escherichia coli. Essential arginine residue at the pyridoxal 5'-phosphate binding site.
Topics: Apoenzymes; Arginine; Binding Sites; Diacetyl; Escherichia coli; Kinetics; L-Serine Dehydratase; Protein Binding; Pyridoxal Phosphate | 1976 |
Functional arginine in the active center of rat liver cystathionase.
Topics: Animals; Arginine; Binding Sites; Binding, Competitive; Cystathionine gamma-Lyase; Cysteine; Diacetyl; Homoserine; Liver; Lyases; Pyridoxal Phosphate; Rats | 1977 |
Arginine and lysine residues as NADH-binding sites in NADH-nitrate reductase from spinach.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Diacetyl; Humans; Lysine; Molecular Sequence Data; NAD; NADH, NADPH Oxidoreductases; Nitrate Reductase (NADH); Nitrate Reductases; Phenylglyoxal; Plants; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid | 1992 |
Active site studies of human immunodeficiency virus reverse transcriptase.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Chromatography, High Pressure Liquid; Ethylmaleimide; HIV; HIV Reverse Transcriptase; HIV-1; Kinetics; Molecular Sequence Data; Peptide Fragments; Phenylglyoxal; Pyridoxal Phosphate; Recombinant Proteins; Reverse Transcriptase Inhibitors; Ribonuclease H; RNA-Directed DNA Polymerase; Sequence Homology, Nucleic Acid; Trypsin | 1992 |
Inactivation of Escherichia coli 2-amino-3-ketobutyrate CoA ligase by phenylglyoxal and identification of an active-site arginine peptide.
Topics: Acetyltransferases; Amino Acids; Apoenzymes; Arginine; Binding Sites; Escherichia coli; Kinetics; Peptide Mapping; Phenylglyoxal; Pyridoxal Phosphate | 1992 |
Effect of substitution of a lysyl residue that binds pyridoxal phosphate in thermostable D-amino acid aminotransferase by arginine and alanine.
Topics: Alanine; Alanine Transaminase; Arginine; Base Sequence; Cloning, Molecular; D-Alanine Transaminase; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Plasmids; Pyridoxal Phosphate; Recombinant Proteins; Restriction Mapping; Spectrophotometry; Thermodynamics | 1991 |
Chemical modification by pyridoxal 5'-phosphate and cyclohexane-1,2-dione indicates that Lys-7 and Arg-10 are involved in the p2 phosphate-binding subsite of bovine pancreatic ribonuclease A.
Topics: Animals; Arginine; Binding Sites; Cattle; Cyclohexanes; Cyclohexanones; Lysine; Phosphates; Pyridoxal Phosphate; Ribonuclease, Pancreatic | 1990 |
Escherichia coli and Saccharomyces cerevisiae acetylornithine aminotransferase: evolutionary relationship with ornithine aminotransferase.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Biological Evolution; Escherichia coli; Genes, Bacterial; Genes, Fungal; Molecular Sequence Data; Pyridoxal Phosphate; Saccharomyces cerevisiae; Substrate Specificity; Transaminases | 1990 |
The beta subunit of tryptophan synthase. Clarification of the roles of histidine 86, lysine 87, arginine 148, cysteine 170, and cysteine 230.
Topics: Arginine; Binding Sites; Cloning, Molecular; Cysteine; DNA Mutational Analysis; Histidine; Lysine; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Spectrum Analysis; Tryptophan Synthase | 1989 |
Contribution of a conserved arginine near the active site of Escherichia coli D-serine dehydratase to cofactor affinity and catalytic activity.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; DNA, Recombinant; Escherichia coli; Kinetics; L-Serine Dehydratase; Molecular Sequence Data; Mutation; Plasmids; Protein Binding; Pyridoxal Phosphate | 1989 |
Modulation of arginine decarboxylase activity from Mycobacterium smegmatis. Evidence for pyridoxal-5'-phosphate-mediated conformational changes in the enzyme.
Topics: Apoenzymes; Arginine; Carboxy-Lyases; Chromatography, Gel; Dialysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Mycobacterium; Protein Conformation; Protein Denaturation; Pyridoxal Phosphate; Spectrophotometry | 1989 |
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases | 1988 |
Substitution of an arginyl residue for the active site lysyl residue (Lys258) of aspartate aminotransferase.
Topics: Amino Acid Sequence; Arginine; Aspartate Aminotransferases; Binding Sites; Circular Dichroism; Escherichia coli; Lysine; Mutation; Pyridoxal Phosphate; Spectrophotometry; Structure-Activity Relationship | 1987 |
Affinity labeling of Escherichia coli DNA polymerase I by 5'-fluorosulfonylbenzoyladenosine. Identification of the domain essential for polymerization and Arg-682 as the site of reactivity.
Topics: Adenosine; Affinity Labels; Arginine; Binding Sites; DNA Polymerase I; Escherichia coli; Nucleotides; Pyridoxal Phosphate | 1988 |
Inhibited thrombins. Interactions with fibrinogen and fibrin.
Topics: Amino Acid Chloromethyl Ketones; Arginine; Binding Sites; Chromatography, Affinity; Dansyl Compounds; Dipeptides; Fibrin; Fibrinogen; Fluorescent Dyes; Hirudins; Phenylmethylsulfonyl Fluoride; Protein Binding; Pyridoxal Phosphate; Thrombin | 1987 |
Chemical properties of Escherichia coli lysine decarboxylase including a segment of its pyridoxal 5'-phosphate binding site.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Binding Sites; Carboxy-Lyases; Chymotrypsin; Cross Reactions; Enzyme Activation; Enzyme Induction; Escherichia coli; Freeze Drying; Glutamates; Immunodiffusion; Lysine; Peptide Fragments; Protein Binding; Protein Denaturation; Pyridoxal Phosphate; Sulfhydryl Compounds; Thermolysin | 1974 |
Polyamine biosynthesis and vitamin B6 deficiency. Evidence for pyridoxal phosphate as coenzyme for S-adenosylmethionine decarboxylase.
Topics: Animals; Arginine; Brain; Carbon Radioisotopes; Carboxy-Lyases; Chromatography, Ion Exchange; Enzyme Activation; Liver; Male; Organ Specificity; Ornithine; Polyamines; Putrescine; Pyridoxal Phosphate; Rats; S-Adenosylmethionine; Spermidine; Spermine; Ultracentrifugation; Vitamin B 6 Deficiency | 1974 |
Inhibition of vaccinia virus replication by canavanine and canaline.
Topics: Amino Acids; Arginine; Canavanine; Carbon Radioisotopes; Depression, Chemical; DNA, Neoplasm; HeLa Cells; Humans; Neoplasm Proteins; Ornithine; Pyridoxal Phosphate; RNA, Neoplasm; Stereoisomerism; Thymidine; Tritium; Uridine; Vaccinia virus; Virus Replication | 1974 |
Coenzymatic activity of pyridoxal 5'-sulfate and related analogues of pyridoxal 5'-phosphate.
Topics: Apoproteins; Arginine; Carboxy-Lyases; Coenzymes; Kinetics; L-Serine Dehydratase; Picolines; Pyridoxal; Pyridoxal Phosphate; Pyridoxine; Spectrum Analysis; Sulfates; Tryptophanase | 1972 |
Biosynthetic arginine decarboxylase from Escherichia coli. Purification and properties.
Topics: Amino Acids; Ammonium Sulfate; Arginine; Carboxy-Lyases; Chemical Precipitation; Chromatography; Chromatography, Ion Exchange; Electrophoresis, Disc; Enzyme Activation; Escherichia coli; Feedback; Hydrogen-Ion Concentration; Hydroxyapatites; Kinetics; Macromolecular Substances; Magnesium; Molecular Weight; Protein Binding; Putrescine; Pyridoxal Phosphate; Sodium Dodecyl Sulfate; Spermidine; Ultracentrifugation | 1973 |
Biosynthetic arginine decarboxylase from Escherichia coli. Subunit interactions and the role of magnesium ion.
Topics: Arginine; Carboxy-Lyases; Chromatography, Gel; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Macromolecular Substances; Magnesium; Molecular Weight; Protein Binding; Putrescine; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry; Ultracentrifugation | 1973 |
Argenine decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme.
Topics: Arginine; Binding Sites; Canavanine; Carboxy-Lyases; Chemical Precipitation; Chromatography, Ion Exchange; Crystallization; Cysteine; Dialysis; Electrophoresis, Disc; Escherichia coli; Guanidines; Hydrogen-Ion Concentration; Kinetics; Lysine; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis; Temperature; Ultracentrifugation; Ultraviolet Rays | 1968 |
Arginine decarboxylase from Escherichia coli. II. Dissociation and reassociation of subunits.
Topics: Arginine; Aspartic Acid; Binding Sites; Carboxy-Lyases; Chemical Phenomena; Chemistry, Physical; Dialysis; Escherichia coli; Glutamates; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Molecular Weight; Pyridoxal Phosphate; Ultracentrifugation | 1968 |
Isolation and characterization of arginine-inducible acetylornithine delta-transaminase from Escherichia coli.
Topics: Animals; Arginine; Copper; Cystine; Electrophoresis, Disc; Enzyme Induction; Enzyme Repression; Escherichia coli; Glutamates; Hydrogen-Ion Concentration; Immunoelectrophoresis; Ketoglutaric Acids; Mercury; Molecular Weight; Ornithine; Pyridoxal Phosphate; Rabbits; Transaminases; Ultracentrifugation | 1970 |
Arginine decarboxylase from Escherichia coli. IV. Structure of the pyridoxal phosphate binding site.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acids; Arginine; Autoanalysis; Binding Sites; Borohydrides; Carbon Isotopes; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Dansyl Compounds; Escherichia coli; Fluorescence; Glutamates; Histidine; Lysine; Methods; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Schiff Bases; Thiocyanates; Trypsin | 1971 |
Phosphorylated analogs of vitamin B 6 modified in the 5' position and on the phosphate group: synthesis and interaction with pyridoxine phosphate oxidase and certain apoenzymes.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Aspartate Aminotransferases; Binding Sites; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glutamates; Hydro-Lyases; L-Serine Dehydratase; Liver; Magnetic Resonance Spectroscopy; Phosphoric Acids; Phosphorylases; Pyridoxal Phosphate; Pyridoxine; Rabbits; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Ultraviolet Rays | 1972 |
Effect of the alpha-hydrazino analogue of histidine on histidine transport and arginine biosynthesis.
Topics: Arginine; Biological Transport; Escherichia coli; Histidine; Hydrazines; Molecular Biology; Mutation; Pyridoxal Phosphate; Salmonella typhimurium; Spectrophotometry; Transaminases | 1966 |
Coenzymatic activity of homologues of pyridoxal phosphate.
Topics: Arginine; Aspartate Aminotransferases; Carboxy-Lyases; Chemical Phenomena; Chemistry; Coenzymes; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; L-Serine Dehydratase; Lyases; Pyridoxal Phosphate; Spectrum Analysis | 1967 |
Arginine racemase of Pseudomonas graveolens. I. Purification, crystallization, and properties.
Topics: Alcohols; Amides; Aminobutyrates; Arginine; Boron Compounds; Catalysis; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Citrulline; Crystallization; Drug Stability; Ethionine; Glutamates; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Isomerases; Kinetics; Light; Lysine; Molecular Weight; Ornithine; Oxidation-Reduction; Penicillamine; Phenylhydrazines; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Quaternary Ammonium Compounds; Rotation; Spectrophotometry; Sulfates; Ultracentrifugation | 1971 |
Arginine racemase of Pseudomonas graveolens. II. Racemization and transamination of ornithine catalyzed by arginine racemase.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Arginine; Catalysis; Dialysis; Electrophoresis; Enzyme Activation; Hydrogen-Ion Concentration; Isomerases; Keto Acids; Ketoglutaric Acids; Kinetics; Light; Models, Biological; Organophosphorus Compounds; Ornithine; Oxaloacetates; Paper; Phenylpyruvic Acids; Picolines; Propionates; Protein Binding; Pseudomonas; Pyridoxal Phosphate; Pyruvates; Rotation; Spectrophotometry; Stereoisomerism; Transaminases; Ultraviolet Rays | 1971 |
Crystalline arginine racemase.
Topics: Arginine; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Isomerases; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Spectrum Analysis; Ultracentrifugation | 1969 |
Crystalline amino acid racemase with low substrate specificity.
Topics: Alanine; Amino Acids; Arginine; Butyrates; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Dialysis; Electrophoresis, Disc; Ethionine; Isomerases; Leucine; Lysine; Methionine; Methods; Molecular Weight; Pseudomonas; Pyridoxal Phosphate; Spectrophotometry; Ultracentrifugation | 1969 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
The reactivity of arginine residues interacting with glucose 1-phosphate in glycogen phosphorylase. A comparison between pyridoxal-reconstituted phosphorylase and the native enzyme.
Topics: Animals; Arginine; Autoradiography; Chemical Phenomena; Chemistry; Enzyme Activation; Glucosephosphates; Phosphorylase a; Phosphorylase b; Phosphorylases; Pyridoxal Phosphate; Rabbits; Substrate Specificity | 1983 |
Putrescine biosynthesis in Tetrahymena thermophila.
Topics: Agmatine; Arginine; Carbon Dioxide; Kinetics; Ornithine; Ornithine Decarboxylase; Putrescine; Pyridoxal Phosphate; Tetrahymena | 1984 |
Selective chemical modification of the active sites of the ketoacyl reductase and enoyl reductase of fatty acid synthetase from lactating rat mammary glands.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Acyl Carrier Protein; Alcohol Oxidoreductases; Animals; Arginine; Binding Sites; Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific); Fatty Acid Synthases; Female; Lactation; Lysine; Mammary Glands, Animal; NADP; Oxidoreductases; Phenylglyoxal; Pregnancy; Pyridoxal Phosphate; Rats | 1980 |
Chemical modification of critical catalytic residues of lysine, arginine, and tryptophan in human glucose phosphate isomerase.
Topics: Affinity Labels; Arginine; Bromosuccinimide; Circular Dichroism; Cyclohexanones; Diacetyl; Female; Glucose-6-Phosphate Isomerase; Humans; Kinetics; Lysine; Molecular Weight; Placenta; Pregnancy; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Tryptophan | 1981 |
Properties of crystalline L-ornithine: alpha-ketoglutarate delta-aminotransferase from Bacillus sphaericus.
Topics: Amino Acids; Arginine; Bacillus; Crystallization; Enzyme Induction; Molecular Weight; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Spectrum Analysis; Substrate Specificity; Transaminases | 1981 |
Essential arginine residues at the pyridoxal phosphate binding site of brain gamma-aminobutyrate aminotransferase.
Topics: 4-Aminobutyrate Transaminase; Animals; Arginine; Binding Sites; Brain; Kinetics; Male; Mice; Phenylglyoxal; Protein Binding; Pyridoxal Phosphate; Transaminases | 1980 |
Purification and properties of L-ornithine delta-aminotransferase from gramicidin S-producing Bacillus brevis.
Topics: Amino Acid Sequence; Arginine; Bacillus; Cyclohexanecarboxylic Acids; Gramicidin; Hydrogen-Ion Concentration; Isoelectric Point; Molecular Sequence Data; Ornithine; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Substrate Specificity | 1994 |
Acidic residues important for substrate binding and cofactor reactivity in eukaryotic ornithine decarboxylase identified by alanine scanning mutagenesis.
Topics: Animals; Arginine; Base Sequence; Binding Sites; Eukaryotic Cells; Kinetics; Leishmania donovani; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Ornithine; Ornithine Decarboxylase; Protozoan Proteins; Pyridoxal Phosphate; Recombinant Fusion Proteins; Species Specificity; Substrate Specificity; Trypanosoma brucei brucei | 1995 |
Reactivity of cysteinyl, arginyl, and lysyl residues of Escherichia coli phosphoenolpyruvate carboxykinase against group-specific chemical reagents.
Topics: Arginine; Binding Sites; Cysteine; Diacetyl; Escherichia coli; Glyoxal; Kinetics; Lysine; Phosphoenolpyruvate Carboxykinase (GTP); Pyrenes; Pyridoxal Phosphate; Sulfhydryl Reagents | 1993 |
Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartate Aminotransferases; Binding Sites; Chickens; Crystallography, X-Ray; Hydrogen Bonding; Hydroxylamine; Hydroxylamines; Kinetics; Mitochondria, Heart; Models, Molecular; Oximes; Peptide Fragments; Protein Conformation; Pyridoxal Phosphate; Solutions | 1996 |
Role of Arg-277 in the binding of pyridoxal 5'-phosphate to Trypanosoma brucei ornithine decarboxylase.
Topics: Animals; Arginine; Binding Sites; Circular Dichroism; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry, Ultraviolet; Trypanosoma brucei brucei; Ultrafiltration | 1997 |
Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Borohydrides; Crystallography, X-Ray; Cyanobacteria; Cyclohexanecarboxylic Acids; Dimerization; Escherichia coli; Glutamic Acid; Intramolecular Transferases; Isomerases; Macromolecular Substances; Models, Molecular; Models, Structural; Protein Structure, Secondary; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Substrate Specificity | 1997 |
Site-directed mutagenesis in basic amino acid residues of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.
Topics: Arginine; Binding Sites; Cloning, Molecular; Glutamine; Kinetics; Lysine; Mutagenesis, Site-Directed; Phosphoenolpyruvate Carboxykinase (GTP); Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Saccharomyces cerevisiae; Trypsin | 1997 |
Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition.
Topics: Aminobutyrates; Arginine; Binding Sites; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Enzyme Inhibitors; Gyrate Atrophy; Humans; Models, Molecular; Molecular Sequence Data; Ornithine-Oxo-Acid Transaminase; Pyridoxal Phosphate; Transaminases; Tyrosine | 1997 |
Arginine294 is essential for the inhibition of Anabaena PCC 7120 ADP-glucose pyrophosphorylase by phosphate.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Anabaena; Arginine; Binding Sites; Fructosediphosphates; Glucose-1-Phosphate Adenylyltransferase; Glyceric Acids; Kinetics; Mutagenesis, Site-Directed; Nucleotidyltransferases; Phenylglyoxal; Phosphates; Pyridoxal Phosphate; Recombinant Proteins | 1997 |
Studies on the amino acid residues of the active site of alpha-aspartyl dipeptidase.
Topics: Arginine; Binding Sites; Catalytic Domain; Diethyl Pyrocarbonate; Dipeptidases; Escherichia coli; Kinetics; Lysine; Phenylglyoxal; Pyridoxal Phosphate; Salmonella typhimurium | 1998 |
Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase.
Topics: Alanine Racemase; Arginine; Binding Sites; Carboxylic Acids; Computer Simulation; Crystallography, X-Ray; Geobacillus stearothermophilus; Hydrogen Bonding; Kinetics; Lysine; Models, Molecular; Propionates; Pyridoxal Phosphate; Schiff Bases; Substrate Specificity | 1999 |
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine | 1999 |
Chemical modification of lysine and arginine residues of bovine heart 2-oxoglutarate dehydrogenase: effect on the enzyme activity and regulation.
Topics: Adenosine Diphosphate; Animals; Arginine; Cattle; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ketoglutarate Dehydrogenase Complex; Kinetics; Lysine; Myocardium; Phenylglyoxal; Pyridoxal Phosphate; Thiamine Pyrophosphate; Time Factors | 1998 |
Identification of Arg-12 in the active site of Escherichia coli K1 CMP-sialic acid synthetase.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Conserved Sequence; Cytidine Triphosphate; Enzyme Stability; Escherichia coli; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Acylneuraminate Cytidylyltransferase; Oxidation-Reduction; Protein Denaturation; Pyridoxal Phosphate; Recombinant Fusion Proteins; Sequence Alignment; Thermodynamics | 1999 |
Strain is more important than electrostatic interaction in controlling the pKa of the catalytic group in aspartate aminotransferase.
Topics: Arginine; Asparagine; Aspartate Aminotransferases; Catalytic Domain; Crystallography, X-Ray; Dicarboxylic Acids; DNA Mutational Analysis; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Lysine; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Schiff Bases; Static Electricity; Structure-Activity Relationship | 2001 |
Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase.
Topics: Arginine; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Escherichia coli; Flavin Mononucleotide; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Structure, Secondary; Pyridoxal Phosphate; Pyridoxamine; Pyridoxaminephosphate Oxidase; Stereoisomerism; Substrate Specificity; Tyrosine; Water | 2002 |
The interaction between pyridoxal-5-phosphate and arginine apodocarboxylase.
Topics: Arginine; Coenzymes; Lyases; Phosphates; Pyridoxal Phosphate | 1958 |
ACETYLORNITHINE DELTA-TRANSAMINASE. PARTIAL PURIFICATION AND REPRESSION BEHAVIOR.
Topics: Arginine; Benzoates; Chloromercuribenzoates; Copper; Edetic Acid; Enzyme Inhibitors; Enzyme Repression; Escherichia coli; Keto Acids; Ketoglutaric Acids; Mutation; Ornithine; Pharmacology; Pyridoxal Phosphate; Pyruvates; Research; Spectrophotometry; Transaminases | 1964 |
G-1:C73 recognition by an arginine cluster in the active site of Escherichia coli histidyl-tRNA synthetase.
Topics: Acylation; Alanine; Arginine; Base Pairing; Binding Sites; Computer Simulation; Cytosine; Escherichia coli Proteins; Guanine; Histidine; Histidine-tRNA Ligase; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pyridoxal Phosphate; RNA, Transfer, His; Substrate Specificity | 2004 |
Homocysteine, vitamin B6, and endothelial dysfunction in circulatory disorders.
Topics: Arginine; C-Reactive Protein; Endothelium, Vascular; Homocysteine; Humans; Nitric Oxide; Pyridoxal Phosphate; Stroke; Vitamin B 6; Vitamin B 6 Deficiency | 2004 |
Relationships between structure, function and stability for pyridoxal 5'-phosphate-dependent starch phosphorylase from Corynebacterium callunae as revealed by reversible cofactor dissociation studies.
Topics: Apoproteins; Arginine; Chromatography, Affinity; Circular Dichroism; Corynebacterium; Dimerization; Enzyme Stability; Half-Life; Holoenzymes; Hydrogen-Ion Concentration; Kinetics; Mutation; Polysaccharides; Pyridoxal Phosphate; Spectrometry, Fluorescence; Starch Phosphorylase; Structure-Activity Relationship | 2004 |
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase | 2004 |
Biochemical characterization of the Campylobacter jejuni Cj1294, a novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates UDP-4-amino-4,6-dideoxy-GalNAc.
Topics: Acetylglucosamine; Arginine; Bacterial Proteins; Campylobacter jejuni; Cloning, Molecular; Dimerization; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Transaminases; Uridine Diphosphate N-Acetylgalactosamine | 2005 |
Molecular and biochemical characterization of a serine racemase from Arabidopsis thaliana.
Topics: Alanine; Arabidopsis; Arginine; Catalysis; Cations, Divalent; Dimerization; Escherichia coli; Glutamine; Hydro-Lyases; Hydrogen-Ion Concentration; In Situ Hybridization, Fluorescence; Metals; Molecular Sequence Data; Pyridoxal Phosphate; Racemases and Epimerases; Sequence Homology, Amino Acid; Serine; Stereoisomerism; Substrate Specificity | 2006 |
Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions.
Topics: Apoenzymes; Arginine; Binding Sites; Catalysis; Citrobacter freundii; Crystallography, X-Ray; Enzyme Activation; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Phenylalanine; Potassium; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Molecular evolution of B6 enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B6 protoenzyme.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Evolution, Molecular; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Recombinant Proteins; Ribonuclease, Pancreatic; Vitamin B 6 | 2008 |
Inactive S298R disassembles the dodecameric L-aspartate 4-decarboxylase into dimers.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Computer Simulation; Dimerization; Escherichia coli; Models, Chemical; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Pseudomonas; Pyridoxal Phosphate; Serine | 2008 |
A periplasmic, pyridoxal-5'-phosphate-dependent amino acid racemase in Pseudomonas taetrolens.
Topics: Amino Acid Isomerases; Arginine; Bacterial Proteins; DNA, Bacterial; Escherichia coli; Lysine; Molecular Sequence Data; Ornithine; Periplasm; Protein Processing, Post-Translational; Protein Transport; Pseudomonas; Pyridoxal Phosphate; Recombinant Proteins; Sequence Analysis, DNA; Sequence Analysis, Protein | 2009 |
Dual roles of a conserved pair, Arg23 and Ser20, in recognition of multiple substrates in alpha-aminoadipate aminotransferase from Thermus thermophilus.
Topics: 2-Aminoadipate Transaminase; 2-Aminoadipic Acid; Arginine; Conserved Sequence; Crystallography, X-Ray; Glutamates; Protein Structure, Secondary; Pyridines; Pyridoxal Phosphate; Serine; Substrate Specificity; Thermus thermophilus | 2009 |
NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium.
Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Cell Proliferation; Dose-Response Relationship, Drug; Male; Mice; Models, Neurological; Neurogenesis; Neuropeptide Y; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Neuropeptide Y; Receptors, Purinergic; Sensory Receptor Cells | 2010 |
Disruption of distal interactions of Arg 262 and of substrate binding to Ser 52 affect catalysis of sheep liver cytosolic serine hydroxymethyltransferase.
Topics: Animals; Arginine; Biocatalysis; Cytosol; Enzyme Stability; Glycine Hydroxymethyltransferase; Liver; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Pyridoxal Phosphate; Serine; Sheep; Temperature | 2003 |
Decameric SelA•tRNA(Sec) ring structure reveals mechanism of bacterial selenocysteine formation.
Topics: Arginine; Bacteria; Bacterial Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; RNA, Transfer, Amino Acyl; Selenocysteine; Transferases | 2013 |
Cardiovascular responses to ATP microinjected into the paraventricular nucleus are mediated by nitric oxide and NMDA glutamate receptors in awake rats.
Topics: Adenosine Triphosphate; Animals; Arginine; Blood Pressure; Ganglionic Blockers; Heart Rate; Male; Microinjections; Nitric Oxide; Nitroprusside; Paraventricular Hypothalamic Nucleus; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Quinazolinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Wakefulness | 2013 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Structural basis for the relaxed substrate selectivity of Leishmania mexicana broad specificity aminotransferase.
Topics: Arginine; Aspartic Acid; Crystallization; Crystallography, X-Ray; Dimerization; Glutamic Acid; Leishmania mexicana; Leishmaniasis, Cutaneous; Protein Structure, Tertiary; Protozoan Proteins; Pyridoxal Phosphate; Substrate Specificity; Transaminases | 2015 |
Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent L-Arginine α-Deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway.
Topics: Amidohydrolases; Arginine; Biosynthetic Pathways; Catalytic Domain; Crystallography, X-Ray; Guanidines; Mixed Function Oxygenases; Models, Molecular; Protein Conformation; Pyridoxal Phosphate; Pyrrolidines; Streptomyces; Substrate Specificity; Transaminases | 2015 |
A pyridoxal phosphate-dependent enzyme that oxidizes an unactivated carbon-carbon bond.
Topics: Arginine; Carbon; Catalysis; Deamination; Kinetics; Molecular Conformation; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Pyridoxal Phosphate; Stereoisomerism; Streptomyces griseus | 2016 |
Structural Snapshots of an Engineered Cystathionine-γ-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site.
Topics: Amino Acid Substitution; Arginine; Biocatalysis; Carbon-Sulfur Lyases; Catalytic Domain; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Enzyme Stability; Humans; Hydrogen Bonding; Hydrolysis; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Engineering; Pyridoxal Phosphate; Recombinant Proteins; Selenomethionine; Substrate Specificity | 2017 |
Structural studies on the decameric S. typhimurium arginine decarboxylase (ADC): Pyridoxal 5'-phosphate binding induces conformational changes.
Topics: Amino Acid Motifs; Arginine; Bacterial Proteins; Binding Sites; Carboxy-Lyases; Catalytic Domain; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Substrate Specificity | 2017 |
Snapshots of the Catalytic Cycle of an O
Topics: Amino Acid Oxidoreductases; Arginine; Catalysis; Crystallography, X-Ray; Hydrogen Peroxide; Hydroxylation; Mixed Function Oxygenases; Oxidation-Reduction; Oxygen; Pyridoxal Phosphate | 2018 |
Pharmaceutical compounding of orphan active ingredients in Belgium: how community and hospital pharmacists can address the needs of patients with rare diseases.
Topics: Arginine; Belgium; Carnitine; Drug Compounding; Excipients; Humans; Pharmacists; Phenylbutyrates; Primaquine; Pyridoxal Phosphate; Rare Diseases; Sodium Benzoate | 2019 |
Dysregulation of homocysteine homeostasis in acute intermittent porphyria patients receiving heme arginate or givosiran.
Topics: Acetylgalactosamine; Adult; Arginine; Cystathionine beta-Synthase; Female; Folic Acid; Heme; Homeostasis; Homocysteine; Homocystinuria; Humans; Hydroxymethylbilane Synthase; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Porphyria, Acute Intermittent; Pyridoxal Phosphate; Pyrrolidines; Young Adult | 2021 |
Probing mechanistic questions in the PLP- and O
Topics: Arginine; Humans; Oxidoreductases; Oxygen; Oxygenases; Pyridoxal Phosphate | 2023 |