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pyridostigmine bromide and soman

pyridostigmine bromide has been researched along with soman in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (29.87)	18.7374
1990's	28 (36.36)	18.2507
2000's	19 (24.68)	29.6817
2010's	7 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dirnhuber, P; Green, DM	1
French, MC; Wetherell, JR; White, PD	1
Dirnhuber, P; French, MC; Green, DM; Leadbeater, L; Stratton, JA	1
Alter, SC; Harris, LW; Heyl, WC; Stitcher, DL	1
Buccafusco, JJ; Li, W	1
Anderson, DR; Harris, LW; Lennox, WJ; Woodard, CL	1
Adler, M; Albuquerque, EX; Deshpande, SS; Foster, RE; Maxwell, DM	1
Adams, NL; Groff, WA; Vick, JA; von Bredow, JD	1
Bajgar, J; Fusek, J; Jakl, A; Patocka, J	1
Dun, NJ; Liu, HQ	1
Broomfield, CA; Clark, OE; Ford, KW; Harris, LW; Knight, KR; Ray, R	1
Blick, DW; Brown, GC; Hartgraves, SL; Kerenyi, SZ; Miller, S; Murphy, MR	1
Hartgraves, SL; Kerenyi, SZ; Murphy, MR	1
Anderson, D; Carchman, RA; Carter, WH; Gennings, C; Harris, LW; Lennox, WJ; Solana, RP	1
Kumamoto, E; Shinnick-Gallagher, P	1
Bataillard, A; Blanchet, G; Sannajust, F; Sassard, J; Sentenac-Roumanou, H; Yoccoz, D	1
Gross, CL; Kagey-Sobotka, A; Kilduff, JE; Meier, HL; Papirmeister, B	1
Ellin, RI; Kaminskis, A	1
Patocka, J	1
Anderson, RJ; Chamberlain, WL	1
Brecht, KM; Lenz, DE; Maxwell, DM; O'Neill, BL	1
Clement, JG; Shiloff, JD	1
Bonds, AB; DeBruyn, EJ; Gajewski, YA	1
French, MC; Wetherell, JR	1
Albuquerque, EX; Boyne, AF; Deshpande, SS; Meshul, CK	1
Anderson, DR; Harris, LW; Lennox, WJ; Talbot, BG	1
Inns, RH; Leadbeater, L; Rylands, JM	1
Carchman, RA; Carter, WH; Jones, DE	1
Inns, RH; Leadbeater, L	1
Adams, N; Broomfield, C; Harris, L; Stitcher, D	1
Anderson, DR; Harris, LW; Lennox, WJ; Swanson, DR; Talbot, BG	1
Harris, LW; Hey, WC; Stitcher, DL	1
Harris, LW; Heyl, WC; Stitcher, DL	2
Dola, T; Lipp, J	1
Blanchet, G; Bodjarian, N; Carpentier, P; Denoyer, M; Foquin-Tarricone, A; Kamenka, JM; Lallement, G; Lerner-Natoli, M; Rondouin, G	1
Blick, DW; Brown, GC; Hartgraves, SL; Murphy, MR	1
Blick, DW; Brown, GC; Murphy, MR; Weathersby, FR	1
Smith, AP	1
Blick, DW; Brown, GC; Fanton, JW; Hartgraves, SL; Murphy, MR; Yochmowitz, MG	1
Koplovitz, I; Stewart, JR	1
Blick, DW; Brown, GC; Miller, SA; Murphy, MR	1
Brecht, KM; Doctor, BP; Maxwell, DM; Wolfe, AD	1
Beers, ET; Brennecke, LH; Sparenborg, S	1
Aas, P; Fonnum, F; Haider, T; Walday, P	1
Bajgar, J; Kassa, J	1
Aubriot, S; Baubichon, D; Burckhart, MF; Lallement, G; Masqueliez, C; Veyret, J	1
Fusek, J; Kassa, J	1
Kassa, J	2
Alkalay, D; Chapman, S; Cohen, G; Gilat, E; Rabinovitz, I; Raveh, L; Weissman, BA	1
McDonough, JH; Shih, TM	1
Carpentier, P; de Groot, DM; Foquin, A; Lallement, G; Lerner-Natoli, M; Rondouin, G	1
Ben Nathan, D; Danenberg, HD; Grauer, E; Kapon, J; Kobiler, D; Lustig, S	1
Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G	1
Bierman, EP; Bruijnzeel, PL; Carpentier, P; de Groot, DM; Kulig, BM; Lallement, G; Melchers, BP; Philippens, IH; van Huygevoort, AH	1
Bollman, SR; Bonjour, GN; Brown, BF; Castelo, CS; Crow, JR; Deng, LY; Fink, CJ; Hall, CA; Jurich, AP; Kaufman, M; Krehbiel, M; Lash, JF; Owens, BL; Reppert, EJ; Schumm, WR; Stever, JC; Webb, FJ	1
Baubichon, D; Clarençon, D; Demoncheaux, JP; Dorandeu, F; Foquin, A; Galonnier, M; Lallement, G	1
Albuquerque, EX; Aracava, Y; Castro, NG; Fawcett, WP; Pereira, EF; Randall, WR; Santos, MD	1
Couzin, J	1
Burton, A	1
Kassa, J; Krejcová, G; Samnaliev, I	1
Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM	1
Newmark, J	1
Aisen, PS; Doctor, BP; Feaster, SR; Garcia, GE; Gordon, RK; Haigh, JR; Lenz, DE; Riel, MA	1
Adler, M; Deshpande, SS; Doctor, BP; Gall, KJ; Gordon, RK; Haigh, JR; Johnston, SR; Peters, BM	1
Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA	1
Kellar, KJ	1
Bumm, R; Eckert, S; Eyer, P; Herkert, NM; Thiermann, H; Weber, G; Worek, F	1
Adler, M; Apland, JP; Barham, CB; Deshpande, SS; Desmond, P; Gordon, RK; Haigh, JR; Koplovitz, I; Lenz, DE	1
Follette, D; Graves, G; Henderson, JD; Maselli, RA; Ng, J; Wilson, BW	1
Herkert, NM; Thiermann, H; Worek, F	1
Doctor, BP; Jensen, N; Nambiar, MP; Oguntayo, S; Wang, Y; Wei, Y	1
Bajgar, J; Kassa, J; Koomlova, M; Musilek, K	1
Kassa, J; Korabecny, J; Sepsova, V; Tumova, M	1
Hamilton, LR; Myers, TM; Schachter, SC	1

Reviews

2 review(s) available for pyridostigmine bromide and soman

Article	Year
Therapy for nerve agent poisoning. Archives of neurology, 2004, Volume: 61, Issue:5 Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman	2004
Therapeutic and neuroprotective efficacy of pharmacological pretreatment and antidotal treatment of acute tabun or soman poisoning with the emphasis on pretreatment drug PANPAL. Arhiv za higijenu rada i toksikologiju, 2006, Volume: 57, Issue:4 Topics: Animals; Antidotes; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Combinations; Neuroprotective Agents; Organophosphates; Pyridostigmine Bromide; Soman; Trihexyphenidyl	2006

Article

Year

Therapy for nerve agent poisoning.

Archives of neurology, 2004, Volume: 61, Issue:5

Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman

2004

Therapeutic and neuroprotective efficacy of pharmacological pretreatment and antidotal treatment of acute tabun or soman poisoning with the emphasis on pretreatment drug PANPAL.

Arhiv za higijenu rada i toksikologiju, 2006, Volume: 57, Issue:4

Topics: Animals; Antidotes; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Combinations; Neuroprotective Agents; Organophosphates; Pyridostigmine Bromide; Soman; Trihexyphenidyl

2006

Other Studies

75 other study(ies) available for pyridostigmine bromide and soman

Article	Year
Effectiveness of pyridostigmine in reversing neuromuscular blockade produced by soman. The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:7 Topics: Animals; Cats; Cholinesterases; Female; Guinea Pigs; Haplorhini; In Vitro Techniques; Macaca mulatta; Male; Muscle Contraction; Neuromuscular Junction; Organophosphorus Compounds; Paralysis; Pyridostigmine Bromide; Rabbits; Rats; Soman; Species Specificity; Time Factors	1978
The reversal by pyridostigmine of neuromuscular block produced by soman. The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:5 Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Junction; Organophosphorus Compounds; Phrenic Nerve; Pyridostigmine Bromide; Rats; Soman; Time Factors	1979
The protection of primates against soman poisoning by pretreatment with pyridostigmine. The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:5 Topics: Animals; Atropine; Callitrichinae; Cholinesterases; Female; Haplorhini; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Pyridostigmine Bromide; Soman; Time Factors	1979
Effects of pyridostigmine and cholinolytics on cholinesterase and acetylcholine in Soman poisoned rats. Drug and chemical toxicology, 1978, Volume: 1, Issue:4 Topics: Acetylcholine; Animals; Atropine; Benactyzine; Brain; Cholinesterases; Male; Organophosphate Poisoning; Parasympatholytics; Pyridostigmine Bromide; Rats; Soman; Time Factors	1978
Effectiveness of alpha 2-adrenergic receptor stimulation in reducing the central toxicity following cholinesterase inhibition. Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:1 Topics: Adrenergic alpha-Agonists; Animals; Behavior, Animal; Cholinesterase Inhibitors; Clonidine; Diazepam; Dose-Response Relationship, Drug; Guanabenz; Guanfacine; Lethal Dose 50; Male; Motor Activity; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1992
The effect of pyridostigmine pretreatment on oxime efficacy against intoxication by soman or VX in rats. Drug and chemical toxicology, 1992, Volume: 15, Issue:4 Topics: Animals; Antidotes; Cholinesterase Inhibitors; Male; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Soman	1992
Effects of subacute pyridostigmine administration on mammalian skeletal muscle function. Journal of applied toxicology : JAT, 1992, Volume: 12, Issue:1 Topics: Acetylcholinesterase; Adaptation, Physiological; Animals; Cholinesterase Inhibitors; Depression, Chemical; Diaphragm; Dose-Response Relationship, Drug; Infusion Pumps; Lethal Dose 50; Male; Muscle Contraction; Muscle, Smooth; Muscles; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1992
Effectiveness of oral pyridostigmine pretreatment and cholinolytic-oxime therapy against soman intoxication in nonhuman primates. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 17, Issue:4 Topics: Administration, Oral; Animals; Antidotes; Atropine; Benactyzine; Drug Combinations; Female; Lethal Dose 50; Macaca mulatta; Male; Parasympatholytics; Pyridostigmine Bromide; Soman; Trimedoxime	1991
Efficacy of various pretreatment and therapy regimens against soman lethality in mice. Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1991, Volume: 34, Issue:3 Topics: Animals; Atropine; Diazepam; Female; Male; Mice; Obidoxime Chloride; Poisoning; Pyridostigmine Bromide; Soman; Trihexyphenidyl; Trimedoxime	1991
Effects of verapamil on synaptic transmission in mammalian sympathetic ganglia. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:5 Topics: Action Potentials; Aminopyridines; Animals; Barium; Barium Compounds; Chlorides; Ganglia, Sympathetic; Guinea Pigs; Male; Neurons; Pyridostigmine Bromide; Rabbits; Soman; Synapses; Synaptic Transmission; Verapamil	1990
A novel tertiary pyridostigmine derivative [3-(N,N-dimethylcarbamyloxy)-1-methyl-delta 3-tetrahydropyridine]: anticholinesterase properties and efficacy against soman. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:2 Topics: Acetylcholinesterase; Animals; Antidotes; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Guinea Pigs; Male; Molecular Structure; Pyridostigmine Bromide; Rabbits; Rats; Rats, Inbred Strains; Soman	1991
Behavioral toxicity of anticholinesterases in primates: chronic pyridostigmine and soman interactions. Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:3 Topics: Animals; Behavior, Animal; Cholinesterases; Infusion Pumps, Implantable; Macaca mulatta; Male; Pyridostigmine Bromide; Soman	1991
Toxic interactions between repeated soman and chronic pyridostigmine in rodents. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:2 Topics: Animals; Cholinesterases; Drug Administration Schedule; Drug Implants; Drug Synergism; Male; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1990
Evaluation of the efficacy of two carbamates, physostigmine and pyridostigmine, when used in conjunction for protection against organophosphate exposure. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 15, Issue:4 Topics: Acetylcholinesterase; Animals; Cholinesterase Inhibitors; Female; Guinea Pigs; Lethal Dose 50; Male; Models, Biological; Organophosphorus Compounds; Physostigmine; Pyridostigmine Bromide; Regression Analysis; Soman	1990
Action of an irreversible acetylcholine esterase inhibitor, soman, on muscarinic hyperpolarization in cat bladder parasympathetic ganglia. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Acetylcholine; Animals; Atropine; Cats; Cholinesterase Inhibitors; Electric Stimulation; Female; Ganglia, Parasympathetic; In Vitro Techniques; Male; Muscle Contraction; Pyridostigmine Bromide; Receptors, Muscarinic; Receptors, Nicotinic; Soman	1990
Cardiovascular consequences of organophosphorus poisoning and of antidotes in conscious unrestrained rats. Pharmacology & toxicology, 1990, Volume: 67, Issue:1 Topics: Animals; Anti-Anxiety Agents; Antidotes; Atropine; Benzodiazepines; Benzodiazepinones; Blood Pressure; Diazepam; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1990
Histamine release by esterase inhibitors. The regulation of histamine release from human leukocytes of allergic and non-allergic individuals by the serine esterase inhibitors diisopropyl fluorophosphate and pinacolyl methylphosphorofluoridate. International archives of allergy and applied immunology, 1985, Volume: 77, Issue:1-2 Topics: Enzyme Inhibitors; Esterases; Histamine Release; Humans; Hypersensitivity; Isoflurophate; Kinetics; Organophosphorus Compounds; Physostigmine; Pyridostigmine Bromide; Soman; Temperature	1985
Carbamoylated enzyme reversal as a means of predicting pyridostigmine protection against soman. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:9 Topics: Acetylcholinesterase; Animals; Erythrocytes; Guinea Pigs; Half-Life; Haplorhini; Humans; Indicators and Reagents; Kinetics; Pyridostigmine Bromide; Rabbits; Rats; Soman	1989
Effect of pyridostigmine and syntostigmine pretreatment on the inhibition of acetylcholinesterases by o-pinacolyl-methylphosphonofluoridate. In vitro experiments with rat tissues. Biomedica biochimica acta, 1989, Volume: 48, Issue:9 Topics: Animals; Brain; Cholinesterase Inhibitors; Diaphragm; Erythrocytes; Female; In Vitro Techniques; Kinetics; Male; Neostigmine; Pyridostigmine Bromide; Rats; Respiratory Muscles; Soman	1989
Pyridostigmine-induced decrement in skeletal muscle contracture is not augmented by soman. Neurotoxicology, 1988,Spring, Volume: 9, Issue:1 Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Male; Muscle Contraction; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1988
Effect of carboxylesterase inhibition on carbamate protection against soman toxicity. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3 Topics: Acetylcholinesterase; Animals; Carboxylesterase; Carboxylic Ester Hydrolases; Guinea Pigs; Lethal Dose 50; Male; Organophosphorus Compounds; Physostigmine; Pyridostigmine Bromide; Rabbits; Rats; Rats, Inbred Strains; Soman	1988
Effects of subchronic pyridostigmine pretreatment on the toxicity of soman. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7 Topics: Acetylcholinesterase; Animals; Anticonvulsants; Antidotes; Brain; Ileum; Male; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Soman	1986
Anticholinesterase agents affect contrast gain of the cat cortical visual evoked potential. Neuroscience letters, 1986, Nov-21, Volume: 71, Issue:3 Topics: Acetylcholine; Animals; Atropine; Cats; Cholinesterase Inhibitors; Evoked Potentials, Visual; Isoflurophate; Physostigmine; Pyridostigmine Bromide; Soman; Visual Cortex; Visual Perception	1986
The hydrolysis of succinyldithiocholine and related thiocholine esters by human plasma and purified cholinesterase. Biochemical pharmacology, 1986, Mar-15, Volume: 35, Issue:6 Topics: Adult; Choline; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationship, Drug; Female; Humans; Hydrolysis; Kinetics; Male; Pyridostigmine Bromide; Serum Albumin; Soman; Succinylcholine; Thiocholine	1986
Comparison of the ultrastructural myopathy induced by anticholinesterase agents at the end plates of rat soleus and extensor muscles. Experimental neurology, 1985, Volume: 89, Issue:1 Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Electrophysiology; Female; Microscopy, Electron; Motor Endplate; Muscular Diseases; Nerve Endings; Neuromuscular Junction; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Sarin; Soman; Time Factors	1985
Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality. Life sciences, 1985, Sep-02, Volume: 37, Issue:9 Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mecamylamine; Organophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Soman	1985
Treatment of poisoning by soman. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2 Topics: Animals; Antidotes; Atropine; Carbamates; Diazepam; Guinea Pigs; Male; Motor Activity; Organophosphate Poisoning; Parasympatholytics; Phenylpropionates; Physostigmine; Pyridostigmine Bromide; Sarin; Soman; Time Factors	1985
Assessing pyridostigmine efficacy by response surface modeling. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2 Topics: Animals; Atropine; Cholinesterase Inhibitors; Female; Guinea Pigs; Male; Models, Biological; Pralidoxime Compounds; Pyridostigmine Bromide; Soman	1985
The efficacy of bispyridinium derivatives in the treatment of organophosphonate poisoning in the guinea-pig. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:7 Topics: Animals; Atropine; Diazepam; Female; Guinea Pigs; Obidoxime Chloride; Organophosphate Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Soman	1983
Detoxification of soman and o-cyclopentyl-s-diethylaminoethyl methylphosphonothioate in vivo. Proceedings of the Western Pharmacology Society, 1984, Volume: 27 Topics: Animals; Atropine; Carboxylesterase; Carboxylic Ester Hydrolases; Esterases; Female; Humans; In Vitro Techniques; Inactivation, Metabolic; Macaca fascicularis; Male; Mecamylamine; Organophosphorus Compounds; Organothiophosphates; Organothiophosphorus Compounds; Pyridostigmine Bromide; Rabbits; Rats; Soman; Time Factors	1984
Toxicity of anticholinesterases: interactions of pyridostigmine and physostigmine with soman. Drug and chemical toxicology, 1984, Volume: 7, Issue:5 Topics: Acetylcholinesterase; Animals; Drug Interactions; Lethal Dose 50; Male; Motor Activity; Organophosphorus Compounds; Physostigmine; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Soman	1984
Effects of inhibitors of acetylcholine synthesis on brain acetylcholine and survival in soman-intoxicated animals. Life sciences, 1982, May-31, Volume: 30, Issue:22 Topics: Acetylcholine; Animals; Atropine; Brain; Hemicholinium 3; Injections, Intraventricular; Male; Naphthylvinylpyridine; Organophosphorus Compounds; Pyridines; Pyridostigmine Bromide; Rabbits; Rats; Rats, Inbred Strains; Soman	1982
Protection and induced reactivation of cholinesterase by HS-6 in rabbits exposed to soman. Life sciences, 1981, Oct-26, Volume: 29, Issue:17 Topics: Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Lethal Dose 50; Male; Organophosphate Poisoning; Pralidoxime Compounds; Pyridostigmine Bromide; Rabbits; Soman; Time Factors	1981
comparison of the efficacy of HS-6 versus HI-6 when combined with atropine, pyridostigmine and clonazepam for soman poisoning in the monkey. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 246, Issue:1 Topics: Animals; Atropine; Cholinesterases; Clonazepam; Electroencephalography; Female; Heart Rate; Macaca mulatta; Male; Organophosphate Poisoning; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Respiration; Soman	1980
Effects of carbamates on whole blood cholinesterase activity: chemical protection against soman. Drug and chemical toxicology, 1980, Volume: 3, Issue:3 Topics: Animals; Carbamates; Cholinesterases; Lethal Dose 50; Male; Organophosphorus Compounds; Pyridostigmine Bromide; Rabbits; Soman	1980
Anticonvulsant and antilethal effects of the phencyclidine derivative TCP in soman poisoning. Neurotoxicology, 1994,Winter, Volume: 15, Issue:4 Topics: Animals; Anticonvulsants; Atropine; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Phencyclidine; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Soman	1994
Treatment of nerve gas poisoning. The Medical letter on drugs and therapeutics, 1995, May-12, Volume: 37, Issue:948 Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman	1995
Primate performance decrements following acute soman exposure: failure of chemical countermeasures. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3 Topics: Animals; Atropine; Cholinesterase Reactivators; Cholinesterases; Dose-Response Relationship, Drug; Macaca mulatta; Male; Pralidoxime Compounds; Psychomotor Performance; Pyridostigmine Bromide; Soman	1994
Behavioral toxicity of anticholinesterases in primates: effects of daily repeated soman exposure. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:3 Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Cholinesterases; Macaca mulatta; Male; Physostigmine; Postural Balance; Psychomotor Performance; Pyridostigmine Bromide; Soman	1994
Long-term effects of the anticholinesterases sarin and soman on latencies of muscle action potentials in mouse diaphragm muscle. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:3 Topics: Action Potentials; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Erythrocytes; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Muscles; Sarin; Soman	1993
Acute behavioral toxicity of pyridostigmine or soman in primates. Toxicology and applied pharmacology, 1994, Volume: 126, Issue:2 Topics: Animals; Behavior, Animal; Cholinesterases; Dose-Response Relationship, Drug; Macaca mulatta; Male; Pyridostigmine Bromide; Soman	1994
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit. Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms	1994
Behavioral toxicity of anticholinesterases in primates: chronic physostigmine and soman interactions. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Cholinesterases; Drug Interactions; Injections, Subcutaneous; Macaca mulatta; Male; Physostigmine; Psychomotor Performance; Pyridostigmine Bromide; Soman	1993
Comparison of antidote protection against soman by pyridostigmine, HI-6 and acetylcholinesterase. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3 Topics: Acetylcholinesterase; Animals; Antidotes; Cholinesterase Reactivators; Male; Mice; Mice, Inbred ICR; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Soman	1993
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman. Epilepsy research, 1993, Volume: 14, Issue:2 Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus	1993
Effect of pyridostigmine pretreatment, HI-6 and Toxogonin treatment on rat tracheal smooth muscle response to cholinergic stimulation after organophosphorus inhalation exposure. Archives of toxicology, 1993, Volume: 67, Issue:3 Topics: Administration, Inhalation; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Electric Stimulation; Male; Muscle Contraction; Muscle, Smooth; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trachea	1993
The influence of pharmacological pretreatment on efficacy of HI-6 oxime in combination with benactyzine in soman poisoning in rats. Human & experimental toxicology, 1996, Volume: 15, Issue:5 Topics: Animals; Antidotes; Benactyzine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Corticosterone; Diaphragm; Drug Therapy, Combination; Liver; Male; Muscarinic Antagonists; Obidoxime Chloride; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl; Tyrosine Transaminase	1996
Efficacy of huperzine in preventing soman-induced seizures, neuropathological changes and lethality. Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:5 Topics: Alkaloids; Animals; Brain; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Hippocampus; Male; Neuroprotective Agents; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Seizures; Sesquiterpenes; Soman	1997
Effect of Panpal pretreatment and antidotal treatment (HI-6 plus benactyzine) on respiratory and circulatory function in soman-poisoned rats. Human & experimental toxicology, 1997, Volume: 16, Issue:10 Topics: Acetylcholinesterase; Animals; Antidotes; Benactyzine; Blood Pressure; Brain; Central Nervous System Diseases; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Drug Therapy, Combination; Electrocardiography; Heart Rate; Male; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Respiration; Soman; Trihexyphenidyl	1997
[The effect of pharmacologic prophylaxis with Panpal on acetylcholinesterase activity in the diaphragm and various parts of the brain in rats during treated and untreated Soman poisoning]. Casopis lekaru ceskych, 1998, May-18, Volume: 137, Issue:10 Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Benactyzine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Drug Combinations; Male; Oximes; Poisoning; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl	1998
The involvement of the NMDA receptor complex in the protective effect of anticholinergic drugs against soman poisoning. Neurotoxicology, 1999, Volume: 20, Issue:4 Topics: Animals; Brain; Cholinesterase Inhibitors; Cyclopentanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Flunitrazepam; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Parasympatholytics; Protein Binding; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Scopolamine; Seizures; Soman; Time Factors	1999
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication. Archives of toxicology, 2000, Volume: 74, Issue:3 Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman	2000
Effects of atropine sulphate on seizure activity and brain damage produced by soman in guinea-pigs: ECoG correlates of neuropathology. Neurotoxicology, 2000, Volume: 21, Issue:4 Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Convulsants; Electroencephalography; Guinea Pigs; Male; Muscarinic Antagonists; Neurotoxicity Syndromes; Pyridostigmine Bromide; Seizures; Soman	2000
Viral neuroinvasion as a marker for BBB integrity following exposure to cholinesterase inhibitors. Life sciences, 2001, Jan-19, Volume: 68, Issue:9 Topics: Alphavirus Infections; Animals; Blood-Brain Barrier; Brain; Central Nervous System Diseases; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Lethal Dose 50; Mice; Mice, Inbred ICR; Permeability; Physostigmine; Pyridostigmine Bromide; Sindbis Virus; Soman; Viremia	2001
Subchronic administration of various pretreatments of nerve agent poisoning. II. Compared efficacy against soman toxicity. Drug and chemical toxicology, 2001, Volume: 24, Issue:2 Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Male; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Scopolamine; Seizures; Sesquiterpenes; Soman; Time Factors	2001
Beneficial effects of TCP on soman intoxication in guinea pigs: seizures, brain damage and learning behaviour. Journal of applied toxicology : JAT, 2001, Volume: 21 Suppl 1 Topics: Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Discrimination Learning; Electroencephalography; Guinea Pigs; Male; Muscarinic Antagonists; Neuroprotective Agents; Phencyclidine; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Seizures; Soman	2001
Pyridostigmine bromide and the long-term subjective health status of a sample of over 700 male Reserve Component Gulf War era veterans. Psychological reports, 2002, Volume: 90, Issue:3 Pt 1 Topics: Adult; Chemical Warfare; Chemical Warfare Agents; Cholinesterase Inhibitors; Health Status; Humans; Male; Patient Compliance; Persian Gulf Syndrome; Pyridostigmine Bromide; Soman; Time; Veterans	2002
Subchronic administration of pyridostigmine or huperzine to primates: compared efficacy against soman toxicity. Drug and chemical toxicology, 2002, Volume: 25, Issue:3 Topics: Alkaloids; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Macaca fascicularis; Male; Pyridostigmine Bromide; Seizures; Sesquiterpenes; Soman	2002
Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 304, Issue:1 Topics: Animals; Atropine; Central Nervous System; Cholinesterase Inhibitors; Cholinesterases; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Piperidines; Pirenzepine; Pyramidal Cells; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Receptors, Nicotinic; Soman; Synaptic Transmission	2003
Clinical trials. New rule triggers debate over best way to test drugs. Science (New York, N.Y.), 2003, Mar-14, Volume: 299, Issue:5613 Topics: Advisory Committees; Animals; Biological Warfare; Chemical Warfare Agents; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Humans; Military Personnel; Persian Gulf Syndrome; Poisoning; Pyridostigmine Bromide; Soman; United States; United States Food and Drug Administration; Vaccines	2003
Take your pyridostigmine: that's an (ethical?) order! The Lancet. Neurology, 2003, Volume: 2, Issue:5 Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Clinical Trials as Topic; Drug Approval; Human Experimentation; Humans; Pyridostigmine Bromide; Soman; United States; United States Food and Drug Administration	2003
A comparison of the neuroprotective efficacy of pharmacological pretreatment and antidotal treatment in soman-poisoned rats. Acta medica (Hradec Kralove), 2003, Volume: 46, Issue:3 Topics: Animals; Antidotes; Atropine; Benactyzine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Combinations; Drug Therapy, Combination; Male; Neuroprotective Agents; Oximes; Premedication; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar; Soman; Trihexyphenidyl	2003
Effects of fosphenytoin on nerve agent-induced status epilepticus. Drug and chemical toxicology, 2004, Volume: 27, Issue:1 Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus	2004
Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman. Chemico-biological interactions, 2005, Dec-15, Volume: 157-158 Topics: Administration, Oral; Alkaloids; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Humans; Neuroprotective Agents; Pyridostigmine Bromide; Sesquiterpenes; Soman	2005
Inhibition of guinea pig hemi-diaphragm acetylcholinesterase activity by pyridostigmine bromide and protection against soman toxicity. Chemico-biological interactions, 2005, Dec-15, Volume: 157-158 Topics: Animals; Cholinesterase Inhibitors; Cholinesterases; Diaphragm; Guinea Pigs; Pyridostigmine Bromide; Soman	2005
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents. Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-29, Volume: 103, Issue:35 Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors	2006
Overcoming inhibitions. Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36 Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors	2006
Identical kinetics of human erythrocyte and muscle acetylcholinesterase with respect to carbamate pre-treatment, residual activity upon soman challenge and spontaneous reactivation after withdrawal of the inhibitors. Toxicology, 2008, Apr-18, Volume: 246, Issue:2-3 Topics: Acetylcholinesterase; Carbamates; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Erythrocytes; Humans; Kinetics; Muscle, Skeletal; Physostigmine; Pyridostigmine Bromide; Soman	2008
Protection by pyridostigmine bromide of marmoset hemi-diaphragm acetylcholinesterase activity after soman exposure. Chemico-biological interactions, 2010, Sep-06, Volume: 187, Issue:1-3 Topics: Acetylcholinesterase; Animals; Callithrix; Diaphragm; Dose-Response Relationship, Drug; Erythrocytes; Female; Humans; Male; Pyridostigmine Bromide; Reproducibility of Results; Soman	2010
Protection of human muscle acetylcholinesterase from soman by pyridostigmine bromide. Muscle & nerve, 2011, Volume: 43, Issue:4 Topics: Acetylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Intercostal Muscles; Organ Culture Techniques; Protective Agents; Pyridostigmine Bromide; Soman	2011
In vitro kinetic interactions of pyridostigmine, physostigmine and soman with erythrocyte and muscle acetylcholinesterase from different species. Toxicology letters, 2011, Sep-25, Volume: 206, Issue:1 Topics: Acetylcholinesterase; Animals; Carbamates; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Erythrocytes; Female; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Macaca mulatta; Male; Muscle, Skeletal; Physostigmine; Pyridostigmine Bromide; Soman; Species Specificity; Swine	2011
[+]-Huperzine A protects against soman toxicity in guinea pigs. Neurochemical research, 2011, Volume: 36, Issue:12 Topics: Acetylcholinesterase; Alkaloids; Animals; Blood-Brain Barrier; Body Temperature; Chemical Warfare Agents; Cholinesterase Inhibitors; Guinea Pigs; Male; Neuroprotective Agents; Pyridostigmine Bromide; Seizures; Sesquiterpenes; Soman; Stereoisomerism	2011
A comparison of the efficacy of newly developed reversible inhibitors of acetylcholinesterase with commonly used pyridostigmine as pharmacological pre-treatment of soman-poisoned mice. Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:4 Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Isoquinolines; Lethal Dose 50; Male; Mice; Oximes; Pyridinium Compounds; Pyridostigmine Bromide; Soman	2012
The evaluation of prophylactic efficacy of newly developed reversible inhibitors of acetylcholinesterase in soman-poisoned mice - a comparison with commonly used pyridostigmine. Basic & clinical pharmacology & toxicology, 2014, Volume: 115, Issue:6 Topics: Animals; Antidotes; Cholinesterase Inhibitors; Lethal Dose 50; Male; Mice; Piperazines; Pyridostigmine Bromide; Soman; Tacrine	2014
Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques. Neurochemical research, 2017, Volume: 42, Issue:7 Topics: Alkaloids; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Macaca fascicularis; Male; Pyridostigmine Bromide; Reaction Time; Seizures; Sesquiterpenes; Soman; Time Factors; Treatment Outcome	2017