Page last updated: 2024-08-18

pyridostigmine bromide and pralidoxime

pyridostigmine bromide has been researched along with pralidoxime in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's11 (42.31)18.2507
2000's8 (30.77)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, DR; Harris, LW; Lennox, WJ; Woodard, CL1
Bamforth, JP; Das, SK; Ferry, CB; Kelly, SS1
Dochterman, LW; Gresham, VC; Kaminskis, A; Koplovitz, I; Stewart, JR1
McCart, GM; Poikonen, J; Veatch, RM1
Bonner, GD; Gildengorin, VL; Trail, DS; Wade, CE; Waring, PP; Williams, BF1
Anderson, DR; Green, MD; Harris, LW; Lennox, WJ; Talbot, BG1
Anderson, DR; Harris, LW; Lennox, WJ; Talbot, BG1
Koplovitz, I; Young, GD1
Blick, DW; Brown, GC; Hartgraves, SL; Murphy, MR1
Smith, AP1
Koplovitz, I; Stewart, JR1
Beers, ET; Brennecke, LH; Sparenborg, S1
McDonough, JH; Shih, TM1
Barahona, V; Sánchez-Fortún, S1
Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L1
Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM1
Newmark, J1
Arafat, K; Hasan, MY; Nurulain, SM; Petroianu, GA; Rajan, S1
Kellar, KJ1
Barahona, MV; Sánchez-Fortún, S1
McDonough, JH; O'Donnell, JC; Shih, TM; Skovira, JW1
David, V; Medvedovici, A; Radulescu, M; Voicu, V1
Bealer, SL; Dudek, FE; Pouliot, W; Roach, B1
Al-Saud, AA; Alaska, YA; Almas, A; Malabaey, MAT; Malik, A1

Reviews

1 review(s) available for pyridostigmine bromide and pralidoxime

ArticleYear
Therapy for nerve agent poisoning.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman

2004

Other Studies

25 other study(ies) available for pyridostigmine bromide and pralidoxime

ArticleYear
The effect of pyridostigmine pretreatment on oxime efficacy against intoxication by soman or VX in rats.
    Drug and chemical toxicology, 1992, Volume: 15, Issue:4

    Topics: Animals; Antidotes; Cholinesterase Inhibitors; Male; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Soman

1992
Protection against the effects of anticholinesterases on the latencies of action potentials in mouse skeletal muscles.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Acetylcholinesterase; Acetylcysteine; Action Potentials; Animals; Antioxidants; Cholinesterase Inhibitors; Cholinesterase Reactivators; Electrophysiology; Male; Mice; Microelectrodes; Muscles; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Vitamin E

1992
Evaluation of the toxicity, pathology, and treatment of cyclohexylmethylphosphonofluoridate (CMPF) poisoning in rhesus monkeys.
    Archives of toxicology, 1992, Volume: 66, Issue:9

    Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Lethal Dose 50; Macaca mulatta; Male; Organophosphate Poisoning; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide

1992
Waivers for military use of investigational agents.
    American journal of hospital pharmacy, 1991, Volume: 48, Issue:7

    Topics: Antidotes; Atropine; Botulinum Antitoxin; Drugs, Investigational; Ethics, Pharmacy; Federal Government; Government Regulation; Gulf War; Human Experimentation; Humans; Informed Consent; Military Personnel; Pralidoxime Compounds; Pyridostigmine Bromide; Risk Assessment; Saudi Arabia; United States; Warfare

1991
Prevention and treatment of nerve gas poisoning.
    The Medical letter on drugs and therapeutics, 1990, Nov-16, Volume: 32, Issue:831

    Topics: Animals; Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gas Poisoning; Humans; Pralidoxime Compounds; Protective Clothing; Pyridostigmine Bromide; Respiratory Protective Devices

1990
Effects of atropine, 2-PAM, or pyridostigmine in euvolemic or hemorrhagic conscious swine.
    Military medicine, 1988, Volume: 153, Issue:9

    Topics: Acetylcholinesterase; Animals; Atropine; Blood Pressure; Erythrocytes; Heart Rate; Injections, Intra-Arterial; Pralidoxime Compounds; Pyridostigmine Bromide; Shock, Hemorrhagic; Swine

1988
Oxime-induced decarbamylation and atropine/oxime therapy of guinea pigs intoxicated with pyridostigmine.
    Life sciences, 1987, Feb-09, Volume: 40, Issue:6

    Topics: Acetylcholinesterase; Animals; Atropine; Erythrocytes; Guinea Pigs; Male; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide

1987
Relationship between reversible acetylcholinesterase inhibition and efficacy against soman lethality.
    Life sciences, 1985, Sep-02, Volume: 37, Issue:9

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mecamylamine; Organophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Soman

1985
Acute toxicity of cyclohexylmethylphosphonofluoridate (CMPF) in rhesus monkeys: serum biochemical and hematologic changes.
    Archives of toxicology, 1995, Volume: 69, Issue:6

    Topics: Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Atropine; Biomarkers; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Creatine Kinase; Injections, Intramuscular; L-Lactate Dehydrogenase; Lethal Dose 50; Macaca mulatta; Male; Organophosphorus Compounds; Oximes; Potassium; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Seizures

1995
Treatment of nerve gas poisoning.
    The Medical letter on drugs and therapeutics, 1995, May-12, Volume: 37, Issue:948

    Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman

1995
Primate performance decrements following acute soman exposure: failure of chemical countermeasures.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: Animals; Atropine; Cholinesterase Reactivators; Cholinesterases; Dose-Response Relationship, Drug; Macaca mulatta; Male; Pralidoxime Compounds; Psychomotor Performance; Pyridostigmine Bromide; Soman

1994
Long-term effects of the anticholinesterases sarin and soman on latencies of muscle action potentials in mouse diaphragm muscle.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:3

    Topics: Action Potentials; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Erythrocytes; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Muscles; Sarin; Soman

1993
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
    Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms

1994
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus

1993
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman

2000
The use of carbamates, atropine, and 2-pyridine aldoxime methoiodide in the protection of Artemia salina against poisoning by carbophenothion.
    Environmental toxicology and chemistry, 2001, Volume: 20, Issue:9

    Topics: Animals; Artemia; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Drug Interactions; Insecticides; Lethal Dose 50; Muscarinic Antagonists; Organothiophosphorus Compounds; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Water Pollutants, Chemical

2001
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
    Toxicology, 2003, Jun-30, Volume: 188, Issue:2-3

    Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures

2003
Effects of fosphenytoin on nerve agent-induced status epilepticus.
    Drug and chemical toxicology, 2004, Volume: 27, Issue:1

    Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus

2004
Effect of pyridostigmine, pralidoxime and their combination on survival and cholinesterase activity in rats exposed to the organophosphate paraoxon.
    Archives of toxicology, 2006, Volume: 80, Issue:11

    Topics: Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cholinesterases; Drug Administration Schedule; Erythrocytes; Female; Male; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Wistar

2006
Overcoming inhibitions.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors

2006
Toxicity and characterization of cholinesterase-inhibition induced by diisopropyl fluorophosphate in Artemia salina larvae.
    Ecotoxicology and environmental safety, 2009, Volume: 72, Issue:3

    Topics: Animals; Artemia; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Drug Therapy, Combination; Isoflurophate; Larva; Longevity; Muscarinic Antagonists; Physostigmine; Pralidoxime Compounds; Pyridostigmine Bromide; Toxicity Tests, Acute; Water Pollutants, Chemical

2009
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
    Journal of molecular neuroscience : MN, 2010, Volume: 40, Issue:1-2

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diacetyl; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Guinea Pigs; Injections, Intramuscular; Male; Muscarinic Antagonists; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Sarin; Seizures; Treatment Outcome; Up-Regulation

2010
Retention study of some cation-type compounds using bile acid sodium salts as ion pairing agents in liquid chromatography.
    Biomedical chromatography : BMC, 2011, Volume: 25, Issue:8

    Topics: Bile Acids and Salts; Cations; Cholinesterase Inhibitors; Cholinesterase Reactivators; Chromatography, Reverse-Phase; Methanol; Oximes; Pralidoxime Compounds; Pyridostigmine Bromide; Regression Analysis

2011
A rodent model of human organophosphate exposure producing status epilepticus and neuropathology.
    Neurotoxicology, 2016, Volume: 56

    Topics: Animals; Antidotes; Atropine; Central Nervous System Diseases; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Male; Organophosphates; Phosphoric Triester Hydrolases; Pralidoxime Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Status Epilepticus

2016
Pyridostigmine Suicidal Attempt in a Myasthenia Gravis Patient.
    The American journal of case reports, 2019, Sep-26, Volume: 20

    Topics: Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Humans; Middle Aged; Muscarinic Antagonists; Myasthenia Gravis; Pralidoxime Compounds; Pyridostigmine Bromide; Suicide, Attempted

2019