Compounds > pyridostigmine bromide
Page last updated: 2024-08-18

pyridostigmine bromide and huperzine a

pyridostigmine bromide has been researched along with huperzine a in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubriot, S; Baubichon, D; Burckhart, MF; Lallement, G; Masqueliez, C; Veyret, J1
Ariel, N; Barak, D; Bino, T; Ordentlich, A; Shafferman, A; Velan, B1
Aubriot, S; Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G1
Baubichon, D; Carpentier, P; Dorandeu, F; Foquin, A; Lallement, G1
Baubichon, D; Clarençon, D; Demoncheaux, JP; Dorandeu, F; Foquin, A; Galonnier, M; Lallement, G1
Aisen, PS; Doctor, BP; Feaster, SR; Garcia, GE; Gordon, RK; Haigh, JR; Lenz, DE; Riel, MA1
Eckert, S; Eyer, P; Mückter, H; Worek, F1
Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA1
Doctor, BP; Jensen, N; Nambiar, MP; Oguntayo, S; Wang, Y; Wei, Y1
Hamilton, LR; Myers, TM; Schachter, SC1

Other Studies

10 other study(ies) available for pyridostigmine bromide and huperzine a

ArticleYear
Efficacy of huperzine in preventing soman-induced seizures, neuropathological changes and lethality.
    Fundamental & clinical pharmacology, 1997, Volume: 11, Issue:5

    Topics: Alkaloids; Animals; Brain; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Hippocampus; Male; Neuroprotective Agents; Pyridostigmine Bromide; Receptors, N-Methyl-D-Aspartate; Seizures; Sesquiterpenes; Soman

1997
The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.
    The Biochemical journal, 1998, Oct-01, Volume: 335 ( Pt 1)

    Topics: Acetylcholinesterase; Alkaloids; Binding Sites; Cholinesterase Inhibitors; Crystallography, X-Ray; Humans; Hydrogen Bonding; Kinetics; Ligands; Models, Chemical; Models, Molecular; Physostigmine; Protein Conformation; Pyridostigmine Bromide; Sesquiterpenes; Structure-Activity Relationship; Tacrine

1998
Subchronic administration of various pretreatments of nerve agent poisoning. I. Protection of blood and central cholinesterases, innocuousness towards blood-brain barrier permeability.
    Drug and chemical toxicology, 2001, Volume: 24, Issue:2

    Topics: Alkaloids; Animals; Blood-Brain Barrier; Brain; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Evans Blue; Guinea Pigs; Male; Microscopy, Fluorescence; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Serum Albumin; Sesquiterpenes

2001
Subchronic administration of various pretreatments of nerve agent poisoning. II. Compared efficacy against soman toxicity.
    Drug and chemical toxicology, 2001, Volume: 24, Issue:2

    Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Electroencephalography; Guinea Pigs; Male; Neuroprotective Agents; Physostigmine; Pyridostigmine Bromide; Scopolamine; Seizures; Sesquiterpenes; Soman; Time Factors

2001
Subchronic administration of pyridostigmine or huperzine to primates: compared efficacy against soman toxicity.
    Drug and chemical toxicology, 2002, Volume: 25, Issue:3

    Topics: Alkaloids; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Macaca fascicularis; Male; Pyridostigmine Bromide; Seizures; Sesquiterpenes; Soman

2002
Oral administration of pyridostigmine bromide and huperzine A protects human whole blood cholinesterases from ex vivo exposure to soman.
    Chemico-biological interactions, 2005, Dec-15, Volume: 157-158

    Topics: Administration, Oral; Alkaloids; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Humans; Neuroprotective Agents; Pyridostigmine Bromide; Sesquiterpenes; Soman

2005
Kinetic analysis of the protection afforded by reversible inhibitors against irreversible inhibition of acetylcholinesterase by highly toxic organophosphorus compounds.
    Biochemical pharmacology, 2006, Jul-28, Volume: 72, Issue:3

    Topics: Acetylcholinesterase; Algorithms; Alkaloids; Carbamates; Cholinesterase Inhibitors; Cholinesterase Reactivators; Dose-Response Relationship, Drug; Erythrocytes; Humans; Kinetics; Organophosphorus Compounds; Paraoxon; Physostigmine; Pyridostigmine Bromide; Sesquiterpenes; Time Factors

2006
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-29, Volume: 103, Issue:35

    Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors

2006
[+]-Huperzine A protects against soman toxicity in guinea pigs.
    Neurochemical research, 2011, Volume: 36, Issue:12

    Topics: Acetylcholinesterase; Alkaloids; Animals; Blood-Brain Barrier; Body Temperature; Chemical Warfare Agents; Cholinesterase Inhibitors; Guinea Pigs; Male; Neuroprotective Agents; Pyridostigmine Bromide; Seizures; Sesquiterpenes; Soman; Stereoisomerism

2011
Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques.
    Neurochemical research, 2017, Volume: 42, Issue:7

    Topics: Alkaloids; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Convulsants; Macaca fascicularis; Male; Pyridostigmine Bromide; Reaction Time; Seizures; Sesquiterpenes; Soman; Time Factors; Treatment Outcome

2017