pyridine has been researched along with ml253 in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Blobaum, AL; Bridges, TM; Conn, PJ; Daniels, JS; Hopkins, CR; Jones, CK; Lamsal, A; Le, U; Lindsley, CW; Melancon, BJ; Niswender, CM; Rodriguez, AL; Sheffler, DJ; Utley, TJ; Venable, D; Vinson, PN; Wood, MR | 1 |
1 other study(ies) available for pyridine and ml253
Article | Year |
---|---|
Discovery of a selective M₄ positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia.
Topics: Allosteric Regulation; Amides; Animals; Brain; Cholinergic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Half-Life; Humans; Protein Binding; Pyridines; Rats; Receptor, Muscarinic M4; Schizophrenia; Structure-Activity Relationship; Thiophenes | 2013 |