Compounds > pyridazine
Page last updated: 2024-08-21

pyridazine and pyridine

pyridazine has been researched along with pyridine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T1
Fotsch, C; St Jean, DJ1
Eisman, MS; Gu, C; Harrison, RA; Hu, H; Johannes, JW; Kazmirski, S; Lamb, ML; Lyne, PD; Mikule, K; Peng, B; Scott, DA; Su, N; Sylvester, MA; Wang, W; Ye, Q; Zheng, X1
Kwong, P; Sasseville, D; Yu, K1
Cai, ZL; Reimers, JR1
Andrews, PS; Boezio, AA; Boezio, CM; Bush, TL; Cai, T; Cheng, AC; Choquette, D; Coats, JR; Colletti, AE; Copeland, KW; DuPont, M; Graceffa, R; Grubinska, B; Kim, JL; La, DS; Lewis, RT; Liu, J; Mullady, EL; Peterson, EA; Potashman, MH; Romero, K; Shaffer, PL; Stanton, MK; Stellwagen, JC; Teffera, Y; Yi, S1
Alves, WA; da Silva, EF1
Kaur, J; Pal, B1
Davis, SR; Veals, JD1
Batista, ER; Birnbaum, ER; John, KD; Martin, RL; Wilson, JJ1
Beigelman, L; Blatt, L; Chanda, S; Deval, J; Dyatkina, N; Hu, Y; Jekle, A; Jin, Z; Kinkade, A; Prhavc, M; Rajwanshi, VK; Smith, DB; Symons, JA; Tam, Y; Wan, J; Wang, G; Wu, X; Zhang, Q1

Reviews

1 review(s) available for pyridazine and pyridine

ArticleYear
Mitigating heterocycle metabolism in drug discovery.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats

2012

Other Studies

10 other study(ies) available for pyridazine and pyridine

ArticleYear
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:10

    Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase

1981
Modulating the strength of hydrogen bond acceptors to achieve low Caco2 efflux for oral bioavailability of PARP inhibitors blocking centrosome clustering.
    Bioorganic & medicinal chemistry letters, 2016, 10-01, Volume: 26, Issue:19

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Centrosome; Dogs; Humans; Hydrogen Bonding; Madin Darby Canine Kidney Cells; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Rats

2016
Narrow spectrum of cross-sensitization with pyridine derivatives.
    Contact dermatitis, 1998, Volume: 38, Issue:4

    Topics: Dermatitis, Allergic Contact; Dermatitis, Occupational; Humans; Irritants; Occupational Exposure; Patch Tests; Pyridazines; Pyridines; Pyrimidines

1998
Hydrogen bonding and reactivity of water to azines in their S1 (n,π*) electronic excited states in the gas phase and in solution.
    Physical chemistry chemical physics : PCCP, 2012, Jul-07, Volume: 14, Issue:25

    Topics: Computer Simulation; Dimerization; Hydrogen Bonding; Models, Chemical; Photochemical Processes; Protons; Pyrazines; Pyridazines; Pyridines; Pyrimidines; Quantum Theory; Water

2012
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Animals; Benzimidazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Imidazoles; Male; Mice; Microsomes, Liver; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridazines; Pyridines; Rats, Sprague-Dawley; Signal Transduction; Structure-Activity Relationship; TOR Serine-Threonine Kinases

2012
A Raman study on preferential interactions in the formamide/pyridine/pyridazine system and complementary thermodynamic information on the formamide/pyridazine mixture.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 102

    Topics: Binding Sites; Formamides; Protons; Pyridazines; Pyridines; Spectrum Analysis, Raman; Thermodynamics

2013
Photocatalytic degradation of N-heterocyclic aromatics-effects of number and position of nitrogen atoms in the ring.
    Environmental science and pollution research international, 2013, Volume: 20, Issue:6

    Topics: Catalysis; Heterocyclic Compounds; Kinetics; Molecular Structure; Nitrogen; Photolysis; Pyrazines; Pyridazines; Pyridines; Volatile Organic Compounds

2013
Isomerization barriers for the disrotatory and conrotatory isomerizations of 3-aza-benzvalene and 3,4-diaza-benzvalene to pyridine and pyridazine.
    Physical chemistry chemical physics : PCCP, 2013, Aug-28, Volume: 15, Issue:32

    Topics: Aza Compounds; Pyridazines; Pyridines; Quantum Theory; Stereoisomerism

2013
Synthesis and characterization of nitrogen-rich macrocyclic ligands and an investigation of their coordination chemistry with lanthanum(III).
    Inorganic chemistry, 2015, Jan-05, Volume: 54, Issue:1

    Topics: Coordination Complexes; Crystallography, X-Ray; Cyclams; Heterocyclic Compounds; Kinetics; Lanthanoid Series Elements; Macrocyclic Compounds; Mesylates; Molecular Conformation; Nitrogen; Pyrazines; Pyridazines; Pyridines; Pyrimidines; Quantum Theory; Stereoisomerism; Thermodynamics

2015
Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C-Nucleosides as Favipiravir (T-705) Analogues.
    Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; Dose-Response Relationship, Drug; Female; Humans; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Nucleosides; Orthomyxoviridae; Pyridazines; Pyridines; Pyrimidines; Structure-Activity Relationship

2016