pyridazine has been researched along with pyrazines in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T | 1 |
| Fotsch, C; St Jean, DJ | 1 |
| Walker, MA | 1 |
| Cho, MK; Kim, SG | 1 |
| Gallego, E; Peral, F | 1 |
| Deepak, HS; Joy, A; Suryaprakash, N | 1 |
| Chevallier, F; Mongin, F; Seggio, A; Vaultier, M | 1 |
| Foote, DB; Scarborough, TD; Uiterwaal, CJ | 1 |
| Cai, ZL; Reimers, JR | 1 |
| Gorfinkiel, JD; Mašín, Z | 1 |
| Kaur, J; Pal, B | 1 |
| Batista, ER; Birnbaum, ER; John, KD; Martin, RL; Wilson, JJ | 1 |
2 review(s) available for pyridazine and pyrazines
| Article | Year |
|---|---|
Mitigating heterocycle metabolism in drug discovery.
Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats | 2012 |
Improvement in aqueous solubility achieved via small molecular changes.
Topics: Carbon; Drug Discovery; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Water | 2017 |
10 other study(ies) available for pyridazine and pyrazines
| Article | Year |
|---|---|
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives.
Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase | 1981 |
Differential induction of rat hepatic microsomal epoxide hydrolase and rGSTA2 by diazines: the role of cytochrome P450 2E1-mediated metabolic activation.
Topics: Acetone; Animals; beta-Naphthoflavone; Biotransformation; Blotting, Northern; Cytochrome P-450 CYP2E1; Enzyme Induction; Enzyme Inhibitors; Epoxide Hydrolases; Glutathione Transferase; Isoenzymes; Male; Microsomes, Liver; Pyrazines; Pyridazines; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Starvation | 1998 |
A study by ultraviolet spectroscopy on the self-association of diazines in aqueous solution.
Topics: Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Models, Chemical; Pyrazines; Pyridazines; Spectrophotometry; Temperature; Ultraviolet Rays | 2003 |
Determination of natural abundance 15N-1H and 13C-1H dipolar couplings of molecules in a strongly orienting media using two-dimensional inverse experiments.
Topics: Carbon Isotopes; Deuterium; Liquid Crystals; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Pyrazines; Pyridazines; Pyrimidines | 2006 |
Lithium-mediated zincation of pyrazine, pyridazine, pyrimidine, and quinoxaline.
Topics: Lithium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pyrazines; Pyridazines; Pyrimidines; Quinoxalines; Zinc | 2007 |
Ultrafast resonance-enhanced multiphoton ionization in the azabenzenes: pyridine, pyridazine, pyrimidine, and pyrazine.
Topics: Ions; Light; Models, Molecular; Pyrazines; Pyridazines; Pyridines; Pyrimidines | 2012 |
Hydrogen bonding and reactivity of water to azines in their S1 (n,π*) electronic excited states in the gas phase and in solution.
Topics: Computer Simulation; Dimerization; Hydrogen Bonding; Models, Chemical; Photochemical Processes; Protons; Pyrazines; Pyridazines; Pyridines; Pyrimidines; Quantum Theory; Water | 2012 |
Shape and core excited resonances in electron collisions with diazines.
Topics: Electrons; Models, Molecular; Pyrazines; Pyridazines; Pyrimidines; Quantum Theory | 2012 |
Photocatalytic degradation of N-heterocyclic aromatics-effects of number and position of nitrogen atoms in the ring.
Topics: Catalysis; Heterocyclic Compounds; Kinetics; Molecular Structure; Nitrogen; Photolysis; Pyrazines; Pyridazines; Pyridines; Volatile Organic Compounds | 2013 |
Synthesis and characterization of nitrogen-rich macrocyclic ligands and an investigation of their coordination chemistry with lanthanum(III).
Topics: Coordination Complexes; Crystallography, X-Ray; Cyclams; Heterocyclic Compounds; Kinetics; Lanthanoid Series Elements; Macrocyclic Compounds; Mesylates; Molecular Conformation; Nitrogen; Pyrazines; Pyridazines; Pyridines; Pyrimidines; Quantum Theory; Stereoisomerism; Thermodynamics | 2015 |