Page last updated: 2024-08-21

pyridazine and benzimidazole

pyridazine has been researched along with benzimidazole in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PS; Boezio, AA; Boezio, CM; Bush, TL; Cai, T; Cheng, AC; Choquette, D; Coats, JR; Colletti, AE; Copeland, KW; DuPont, M; Graceffa, R; Grubinska, B; Kim, JL; La, DS; Lewis, RT; Liu, J; Mullady, EL; Peterson, EA; Potashman, MH; Romero, K; Shaffer, PL; Stanton, MK; Stellwagen, JC; Teffera, Y; Yi, S	1
Filipek, S; Stepniewski, TM	1
Fansa, EK; Martín-Gago, P; Waldmann, H; Wittinghofer, A	1

Reviews

1 review(s) available for pyridazine and benzimidazole

Article	Year
Structure-based development of PDEδ inhibitors. Biological chemistry, 2017, 05-01, Volume: 398, Issue:5-6 Topics: Animals; Benzimidazoles; Cyclic Nucleotide Phosphodiesterases, Type 6; Drug Discovery; Enzyme Inhibitors; Pyridazines	2017

Other Studies

2 other study(ies) available for pyridazine and benzimidazole

Article	Year
Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors. Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15 Topics: Animals; Benzimidazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Imidazoles; Male; Mice; Microsomes, Liver; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridazines; Pyridines; Rats, Sprague-Dawley; Signal Transduction; Structure-Activity Relationship; TOR Serine-Threonine Kinases	2012
Non-peptide ligand binding to the formyl peptide receptor FPR2--A comparison to peptide ligand binding modes. Bioorganic & medicinal chemistry, 2015, Jul-15, Volume: 23, Issue:14 Topics: Benzimidazoles; Binding Sites; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Docking Simulation; Phenylurea Compounds; Protein Conformation; Pyrazolones; Pyridazines; Quinazolinones; Receptors, Formyl Peptide; Receptors, Lipoxin; Structure-Activity Relationship	2015

Article

Year

Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.

Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

Topics: Animals; Benzimidazoles; Binding Sites; Binding, Competitive; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Half-Life; Humans; Imidazoles; Male; Mice; Microsomes, Liver; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridazines; Pyridines; Rats, Sprague-Dawley; Signal Transduction; Structure-Activity Relationship; TOR Serine-Threonine Kinases

2012

Non-peptide ligand binding to the formyl peptide receptor FPR2--A comparison to peptide ligand binding modes.

Bioorganic & medicinal chemistry, 2015, Jul-15, Volume: 23, Issue:14

Topics: Benzimidazoles; Binding Sites; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Docking Simulation; Phenylurea Compounds; Protein Conformation; Pyrazolones; Pyridazines; Quinazolinones; Receptors, Formyl Peptide; Receptors, Lipoxin; Structure-Activity Relationship

2015