Page last updated: 2024-08-23

pyrene and 1-hydroxypyrene

pyrene has been researched along with 1-hydroxypyrene in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.00)18.7374
1990's13 (32.50)18.2507
2000's12 (30.00)29.6817
2010's13 (32.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bos, RP; Jongeneelen, FJ1
Anzion, RB; Bos, RP; Groenendijk, A; Jongeneelen, FJ; Scheepers, PT; Van Aerts, LA; Veenstra, SJ1
Hubert, TD; Keimig, SD; Keiser, JE; Kirby, KW; Morgan, DP1
Anke, H; Kremer, S; Lambert, M1
Heikkilä, P; Luotamo, M; Pyy, L; Riihimäki, V1
Viau, C; Vyskocil, A1
Kuljukka, T; Peltonen, K; Sorsa, M; Vaaranrinta, R; Veidebaum, T1
Hakala, E; Kakko, K; Lapinlampi, T; Lisko, A; Mäkelä, M; Pyy, L; Vähäkangas, K; Yrjänheikki, E1
Apostoli, P; Cenni, A; Fonte, A; Maccarini, L; Magnaghi, S; Micoli, G; Minoia, C; Nidasio, GF; Roggi, C; Sciarra, GF1
Cazau, MC; Cerniglia, CE; Deck, J; Fritsche, W; Heinze, TM; Sack, U1
Bentsen, RK; Daae, HL; Halgard, K; Notø, H; Ovrebø, S1
Bouchard, M; Viau, C1
Lipniak-Gawlik, M1
Bouchard, M; Krishnan, K; Viau, C1
Airoldi, L; Alcini, D; Berri, A; Carrer, P; Fanelli, R; Guanci, M; La Vecchia, C; Micoli, G; Minoia, C; Negri, E; Pastorelli, R; Restano, J1
Bouchard, M; Carrier, G; Thuot, R; Viau, C1
Cullen, WR; He, TY; Ikonomou, M; Reimer, KJ; Simpson, CD1
Charbonneau, S; Viau, C; Zaoui, C1
Thuot, R; Tzekova, A; Viau, C1
Isse, T; Kawamoto, T; Kim, H; Kim, YD; Matsumoto, A; Oyama, T; Todoroki, H; Uchiyama, I; Yamaguchi, T1
Bains, OS; Kennedy, CJ1
Ekunwe, SI; Hunter, RD; Hwang, HM1
Andersen, O; Dam, E; Rewitz, KF; Styrishave, B1
Gonzalez, FJ; Ito, Y; Kamijima, M; Kim, H; Lee, CH; Nakajima, T; Yamanoshita, O; Yanagiba, Y; Zhang, SY1
Honkanen, JO; Kukkonen, JV; Wiegand, C1
Beydon, D; Champmartin-Gendre, C; Ferrari, E; Lafontaine, M; Marquet, F; Payan, JP; Simon, P1
Kukkonen, JV; Leppänen, MT; Mäenpää, K1
Beach, DG; Croll, RP; Hellou, J; Quilliam, MA; Rouleau, C1
Brozinski, JM; Carrasco Navarro, V; Honkanen, JO; Kronberg, L; Kukkonen, JV; Leppänen, MT1
Chahin, A; Dziurla, MA; Guiavarc'h, YP; Jondreville, C; Rychen, G; Yen, FT1
Heineman, WR; Seliskar, CJ; Talaska, G; Wilson, RA1
Hanel, R; Kammann, U; Nagel, F; Wagner, C1
Bustamante, P; Cassi, R; Clemens, S; Luna-Acosta, A; Thomas-Guyon, H; Warnau, M1
Hessel, S; Lampen, A; Seidel, A1
Espersen, L; Møhl, M; Møller, EF; Nielsen, TG; Nørregaard, RD; Strand, J1
Brinkmann, M; Buchinger, S; Cofalla, C; Eichbaum, K; Hollert, H; Hudjetz, S; Kammann, U; Preuss, T; Reifferscheid, G; Schüttrumpf, H1
Bortey-Sam, N; Darwish, WS; Ikenaka, Y; Ishizuka, M; Kakehi, M; Mizukawa, H; Nakayama, SM; Poapolathep, A; Saengtienchai, A; Terasaki, M; Tsubota, T1
Bartolomé, M; Calvo, E; Castaño, A; Cutanda, F; Esteban, M; González, O; Huetos, O; Pérez-Gómez, B; Ramos, JJ; Ruiz-Moraga, M1
Foroozesh, MK; Guengerich, FP; Kim, D; Kim, JH; Komori, M; Kramlinger, VM; Liu, J; Murayama, N; Shimada, T; Takenaka, S; Yamazaki, H1
Chen, L; Liu, D; Zhang, J; Zhang, Y; Zhu, Y1

Other Studies

40 other study(ies) available for pyrene and 1-hydroxypyrene

ArticleYear
Excretion of pyrene and hydroxypyrene in urine.
    Cancer letters, 1990, May-30, Volume: 51, Issue:2

    Topics: Administration, Oral; Animals; Humans; Pyrenes; Rats; Rats, Inbred Strains

1990
Airborne concentrations, skin contamination, and urinary metabolite excretion of polycyclic aromatic hydrocarbons among paving workers exposed to coal tar derived road tars.
    American Industrial Hygiene Association journal, 1988, Volume: 49, Issue:12

    Topics: Air Pollution; Coal Tar; Environmental Exposure; Humans; Hydrocarbons; Polycyclic Compounds; Pyrenes; Skin

1988
Identification of 1-hydroxypyrene as a major metabolite of pyrene in pig urine.
    Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Mutagens; Pyrenes; Spectrophotometry; Swine

1983
Antimicrobial, phytotoxic, nematicidal, cytotoxic, and mutagenic activities of 1-hydroxypyrene, the initial metabolite in pyrene metabolism by the basidiomycete Crinipellis stipitaria.
    Bulletin of environmental contamination and toxicology, 1995, Volume: 55, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antineoplastic; Antinematodal Agents; Bacteria; Basidiomycota; Benzo(a)pyrene; Biodegradation, Environmental; Caenorhabditis elegans; Daunorubicin; Ethyl Methanesulfonate; Mutagenicity Tests; Mutagens; Plant Development; Plants; Pyrenes; Reference Standards

1995
Urinary 1-naphthol and 1-pyrenol as indicators of exposure to coal tar products.
    International archives of occupational and environmental health, 1995, Volume: 67, Issue:3

    Topics: Air Pollutants, Occupational; Coal Tar; Humans; Mutagens; Naphthalenes; Naphthols; Occupational Exposure; Polycyclic Compounds; Pyrenes

1995
Patterns of 1-hydroxypyrene excretion in volunteers exposed to pyrene by the dermal route.
    The Science of the total environment, 1995, Feb-24, Volume: 163, Issue:1-3

    Topics: Administration, Cutaneous; Coal Tar; Creosote; Half-Life; Humans; Male; Pyrenes; Time Factors; Urine

1995
Exposure to PAH compounds among cokery workers in the oil shale industry.
    Environmental health perspectives, 1996, Volume: 104 Suppl 3

    Topics: Benzo(a)pyrene; Biomarkers; Environmental Monitoring; Estonia; Humans; Industry; Occupational Exposure; Occupations; Pyrenes; Skin

1996
Ambient and biological monitoring of exposure to polycyclic aromatic hydrocarbons at a coking plant.
    The Science of the total environment, 1997, Jun-20, Volume: 199, Issue:1-2

    Topics: Air Pollutants, Occupational; Benzo(a)pyrene; Biomarkers; Chromatography, High Pressure Liquid; Coke; Dust; Environmental Monitoring; Finland; Humans; Longitudinal Studies; Mutagens; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Pyrenes; Reference Standards; Regression Analysis

1997
Urinary 1-hydroxypyrene as a marker of exposure to pyrene: an epidemiological survey on a general population group.
    The Science of the total environment, 1997, Jul-01, Volume: 199, Issue:3

    Topics: Adult; Aged; Alcohol Drinking; Biomarkers; Body Mass Index; Cohort Studies; Creatinine; Diet; Environmental Exposure; Female; Humans; Male; Middle Aged; Mutagens; Pyrenes; Reference Values; Regression Analysis; Smoking; Urine

1997
Novel metabolites in phenanthrene and pyrene transformation by Aspergillus niger.
    Applied and environmental microbiology, 1997, Volume: 63, Issue:7

    Topics: Alkaloids; Aspergillus niger; Carbon Dioxide; Lactams; Mass Spectrometry; Phenanthrenes; Pyrenes; Soil Microbiology

1997
Correlation between urinary 1-hydroxypyrene and ambient air pyrene measured with an inhalable aerosol sampler and a total dust sampler in an electrode paste plant.
    The Science of the total environment, 1998, Mar-05, Volume: 212, Issue:1

    Topics: Adult; Aerosols; Air Pollutants, Occupational; Air Pollution, Indoor; Chromatography, High Pressure Liquid; Dust; Electrodes; Environmental Monitoring; Humans; Middle Aged; Mutagens; Norway; Polycyclic Aromatic Hydrocarbons; Pyrenes; Smoking

1998
Urinary and biliary excretion kinetics of 1-hydroxypyrene following intravenous and oral administration of pyrene in rats.
    Toxicology, 1998, May-15, Volume: 127, Issue:1-3

    Topics: Administration, Oral; Animals; Bile; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mutagens; Pyrenes; Rats; Rats, Sprague-Dawley; Urine

1998
Effect of polycyclic aromatic hydrocarbons on the elimination kinetics of pyrene and the urinary excretion profile of 1-hydroxypyrene in the rat.
    Journal of toxicology and environmental health. Part A, 1998, Dec-11, Volume: 55, Issue:7

    Topics: Administration, Oral; Animals; Body Burden; Hydrocarbons, Aromatic; Hydrocarbons, Cyclic; Injections, Intravenous; Kinetics; Male; Mutagens; Pyrenes; Rats; Rats, Wistar

1998
Kinetics of tissue distribution and elimination of pyrene and 1-hydroxypyrene following intravenous administration of [14C]pyrene in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 46, Issue:1

    Topics: Animals; Carcinogens; Feces; Half-Life; Injections, Intravenous; Male; Pyrenes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Urine

1998
Seasonal effect on airborne pyrene, urinary 1-hydroxypyrene, and benzo(a)pyrene diol epoxide-hemoglobin adducts in the general population.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Air Pollutants; Benzo(a)pyrene; Biomarkers; DNA Adducts; Environmental Monitoring; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Italy; Male; Middle Aged; Mutagens; Pyrenes; Seasons; Smoking; Urban Health

1999
Urinary excretion kinetics of 1-hydroxypyrene in rats subchronically exposed to pyrene or polycyclic aromatic hydrocarbon mixtures.
    Journal of toxicology and environmental health. Part A, 2002, Aug-23, Volume: 65, Issue:16

    Topics: Animals; Fluorescent Dyes; Kinetics; Male; Mutagens; Polycyclic Aromatic Hydrocarbons; Pyrenes; Rats; Rats, Sprague-Dawley

2002
Metabolism of pyrene by two clam species, Mya arenaria and Protothaca staminea.
    Chemosphere, 2002, Volume: 49, Issue:3

    Topics: Animals; Biodegradation, Environmental; Bivalvia; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Pyrenes; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Sulfuric Acid Esters

2002
Dietary fibers reduce the urinary excretion of 1-hydroxypyrene following intravenous administration of pyrene.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 78, Issue:1

    Topics: Adsorption; Algorithms; Animals; Biotransformation; Chromatography, High Pressure Liquid; Dietary Fiber; Feces; Injections, Intravenous; Male; Pyrenes; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

2004
Correlation between biomarkers of polycyclic aromatic hydrocarbon exposure and electrophilic tissue burden in a rat model.
    Archives of toxicology, 2004, Volume: 78, Issue:6

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Algorithms; Animals; Benzopyrenes; Biomarkers; Carcinogens; Chromatography, High Pressure Liquid; Feces; Hemoglobins; Linear Models; Liver; Lung; Male; Myocardium; Protein Binding; Pyrenes; Rats; Rats, Sprague-Dawley; Tissue Distribution

2004
Identification of cytochrome P450 isoforms involved in 1-hydroxylation of pyrene.
    Environmental research, 2004, Volume: 94, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Hydroxylation; Isoenzymes; Kinetics; Mixed Function Oxygenases; Pyrenes

2004
Energetic costs of pyrene metabolism in isolated hepatocytes of rainbow trout, Oncorhynchus mykiss.
    Aquatic toxicology (Amsterdam, Netherlands), 2004, Apr-28, Volume: 67, Issue:3

    Topics: Animals; Biotransformation; Energy Metabolism; Hepatocytes; L-Lactate Dehydrogenase; Mitochondria; Oncorhynchus mykiss; Oxygen Consumption; Pyrenes; Spectrophotometry; Temperature; Xenobiotics

2004
Ultraviolet radiation increases the toxicity of pyrene, 1-aminopyrene and 1-hydroxypyrene to human keratinocytes.
    International journal of environmental research and public health, 2005, Volume: 2, Issue:1

    Topics: Cell Line; Cell Proliferation; Humans; Keratinocytes; Pyrenes; Thymidine; Ultraviolet Rays

2005
Intermoult duration affects the susceptibility of shore crabs Carcinus maenas (L.) to pyrene and their ability to metabolise it.
    Aquatic toxicology (Amsterdam, Netherlands), 2006, Dec-01, Volume: 80, Issue:3

    Topics: Animals; Brachyura; Cytochrome P-450 Enzyme System; DNA Primers; Gene Expression Regulation, Enzymologic; Male; Mixed Function Oxygenases; Molting; Pyrenes; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Time Factors; Water Pollutants, Chemical

2006
Pyrene-induced CYP1A2 and SULT1A1 may be regulated by CAR and not by AhR.
    Toxicology, 2007, Sep-05, Volume: 238, Issue:2-3

    Topics: Animals; Arylsulfotransferase; Blotting, Western; Constitutive Androstane Receptor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Fluorescent Dyes; Genotype; Glucuronates; Glucuronosyltransferase; Hydroxylation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthols; Pyrenes; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Substrate Specificity; Transcription Factors

2007
Humic substances modify accumulation but not biotransformation of pyrene in salmon yolk-sac fry.
    Aquatic toxicology (Amsterdam, Netherlands), 2008, Jan-31, Volume: 86, Issue:2

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Catalase; Cytochrome P-450 CYP1A1; Female; Fresh Water; Glucuronides; Glutathione Transferase; Humic Substances; Pyrenes; Salmo salar; Time Factors; Water Pollutants, Chemical

2008
In vivo and in vitro percutaneous absorption of [14C]pyrene in Sprague Dawley male rats: skin reservoir effect and consequence on urinary 1-OH pyrene excretion.
    Archives of toxicology, 2008, Volume: 82, Issue:10

    Topics: Administration, Cutaneous; Animals; Biomarkers; Carbon Radioisotopes; Carcinogens; In Vitro Techniques; Injections, Intravenous; Male; Pyrenes; Rats; Rats, Sprague-Dawley; Risk Assessment; Skin; Skin Absorption; Urine

2008
Sublethal toxicity and biotransformation of pyrene in Lumbriculus variegatus (Oligochaeta).
    The Science of the total environment, 2009, Apr-01, Volume: 407, Issue:8

    Topics: Animals; Biotransformation; Glucuronates; Heart Rate; Oligochaeta; Pyrenes

2009
Bioaccumulation and biotransformation of pyrene and 1-hydroxypyrene by the marine whelk Buccinum undatum.
    Environmental toxicology and chemistry, 2010, Volume: 29, Issue:4

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Fluorescence; Gastropoda; Mass Spectrometry; Pyrenes; Tissue Distribution; Water Pollutants, Chemical

2010
Inhibition of pyrene biotransformation by piperonyl butoxide and identification of two pyrene derivatives in Lumbriculus variegatus (Oligochaeta).
    Environmental toxicology and chemistry, 2011, Volume: 30, Issue:5

    Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Oligochaeta; Piperonyl Butoxide; Pyrenes; Water Pollutants, Chemical

2011
EROD activity in peripheral blood lymphocytes and 1-hydroxypyrene in urine and milk as biomarkers of PAH exposure in dairy ruminants.
    Environmental toxicology and chemistry, 2011, Volume: 30, Issue:6

    Topics: Animals; Benzo(a)pyrene; Biomarkers; Cytochrome P-450 CYP1A1; Dairying; Environmental Exposure; Environmental Pollutants; Goats; Leukocytes, Mononuclear; Milk; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Pyrenes; Ruminants

2011
Spectroelectrochemical sensing of pyrene metabolites 1-hydroxypyrene and 1-hydroxypyrene-glucuronide.
    Analytical chemistry, 2011, May-15, Volume: 83, Issue:10

    Topics: Air Pollutants, Occupational; Biomarkers; Electrochemical Techniques; Electrodes; Glucuronates; Humans; Oxidation-Reduction; Polycyclic Aromatic Hydrocarbons; Pyrenes; Spectrometry, Fluorescence

2011
Metabolites of polycyclic aromatic hydrocarbons (PAHs) in bile as biomarkers of pollution in European eel (Anguilla anguilla) from German rivers.
    Archives of environmental contamination and toxicology, 2012, Volume: 62, Issue:2

    Topics: Anguilla; Animals; Bile; Biomarkers; Chromatography, High Pressure Liquid; Ecosystem; Environmental Monitoring; Female; Germany; Phenanthrenes; Pyrenes; Rivers; Water Pollutants, Chemical

2012
Bioaccumulation and metabolisation of (14)C-pyrene by the Pacific oyster Crassostrea gigas exposed via seawater.
    Chemosphere, 2012, Volume: 87, Issue:8

    Topics: Animals; Carbon Radioisotopes; Crassostrea; Environmental Monitoring; Kinetics; Pyrenes; Seawater

2012
Polycyclic aromatic hydrocarbons in food--efflux of the conjugated biomarker 1-hydroxypyrene is mediated by Breast Cancer Resistance Protein (ABCG2) in human intestinal Caco-2 cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Arylsulfotransferase; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Biomarkers; Caco-2 Cells; Cytochrome P-450 Enzyme System; Food Contamination; Humans; Neoplasm Proteins; Polycyclic Aromatic Hydrocarbons; Pyrenes; Sulfotransferases

2013
Evaluating pyrene toxicity on Arctic key copepod species Calanus hyperboreus.
    Ecotoxicology (London, England), 2014, Volume: 23, Issue:2

    Topics: Animals; Arctic Regions; Copepoda; Ecosystem; Environmental Monitoring; Female; Food Chain; Greenland; Ovum; Pyrenes; Reproduction; Water Pollutants, Chemical

2014
Physiologically-based toxicokinetic models help identifying the key factors affecting contaminant uptake during flood events.
    Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 152

    Topics: Animals; Bile; Cardiac Output; Floods; Geologic Sediments; Models, Biological; Motor Activity; Oncorhynchus mykiss; Pyrenes; Risk Assessment; Water Pollutants, Chemical

2014
Identification of interspecific differences in phase II reactions: determination of metabolites in the urine of 16 mammalian species exposed to environmental pyrene.
    Environmental toxicology and chemistry, 2014, Volume: 33, Issue:9

    Topics: Animals; Carcinogens; Cats; Cattle; Endocrine Disruptors; Environmental Monitoring; Horses; Humans; Mammals; Polycyclic Aromatic Hydrocarbons; Pyrenes; Swine

2014
Urinary polycyclic aromatic hydrocarbon metabolites levels in a representative sample of the Spanish adult population: The BIOAMBIENT.ES project.
    Chemosphere, 2015, Volume: 135

    Topics: Adult; Biomarkers; Creatinine; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Female; Humans; Male; Middle Aged; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Pyrenes; Spain; Tobacco Smoke Pollution

2015
Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene and 1-acetylpyrene by human cytochrome P450 2A13.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2A6; Humans; Lepidoptera; Models, Biological; Molecular Docking Simulation; Oxidation-Reduction; Polycyclic Compounds; Pyrenes

2016
Interactions of pyrene and/or 1-hydroxypyrene with bovine serum albumin based on EEM-PARAFAC combined with molecular docking.
    Talanta, 2018, Aug-15, Volume: 186

    Topics: Animals; Cattle; Molecular Docking Simulation; Pyrenes; Serum Albumin, Bovine; Software; Spectrometry, Fluorescence

2018