pyrazole and warfarin

pyrazole has been researched along with warfarin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.56)18.7374
1990's3 (16.67)18.2507
2000's1 (5.56)29.6817
2010's10 (55.56)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Honkakoski, P; Lang, MA; Mäenpää, J; Pelkonen, O; Syngelmä, T1
Cederbaum, AI; Feierman, DE; Krikun, G1
Bartsch, H; Kirby, GM; Lang, MA; Pelkonen, P; Wild, CP1
Ding, X; Gu, J; He, W; Lipinskas, TW; Su, T1
Brittebo, EB; Carlsson, C; Franzén, A; Hermansson, V; Lang, M1
Bai, LS; Chen, J; Liu, HF; Liu, JX; Liu, XH; Qi, XB; Song, BA; Yang, Y; Zhu, HL1
Al-Ayed, AS1
Cho, JH; Cuny, GD; Gollapalli, DR; Hedstrom, L; Joachimiak, A; Khan, J; Kim, Y; Makowska-Grzyska, M; Suebsuwong, C; Sun, Z; Vo, P; Zhang, M1
Ganesabaskaran, S; Kandasamy, K; Pachamuthu, MP; Ramanathan, A1
Kesharwani, RK; Kotamraju, S; Santosh, K; Toopurani, MK; Vaarla, K; Vedula, RR1
Jadhav, KM; Kauthale, SS; Pawar, RP; Tekale, SU1
Ben Jannet, H; Chekir, S; Dargère, D; Debbabi, M; Gharbi, R; Laprévote, O; Regazzetti, A1
Chu, MJ; Gong, JX; Liu, H; Lv, XH; Ma, QW; Ren, ZL; Wang, JC; Wang, W1
Dai, H; Ge, S; Huang, M; Li, Y; Ling, Y; Liu, J; Meng, C; Ming, G; Qian, J; Shi, Y; Wang, S; Yao, Y; Zhang, T; Zhang, Y1
Ghasemnejad-Bosra, H; Habibzadeh, S; Haghdadi, M; Heydari-Parastar, S1
Jachak, SM; Kumar, G; Siva Krishna, V; Sriram, D1
Alam, MA; Alnufaie, R; Alsup, N; Andrew Chambers, S; Gilmore, D; Raj Kc, H; Whitt, J1
Coşkun, KA; Gümüş, M; Koca, İ; Tutar, Y1

Other Studies

18 other study(ies) available for pyrazole and warfarin

ArticleYear
Comparative studies on coumarin and testosterone metabolism in mouse and human livers. Differential inhibitions by the anti-P450Coh antibody and metyrapone.
    Biochemical pharmacology, 1991, Aug-22, Volume: 42, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Humans; Metyrapone; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Pyrazoles; Steroid Hydroxylases; Testosterone

1991
Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Butanols; Coumarins; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethanol; Fomepizole; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Pharmaceutical Preparations; Pyrazoles; Rats; Rats, Inbred Strains; Sodium Dodecyl Sulfate; Stereoisomerism

1986
Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.
    Chemico-biological interactions, 1994, Volume: 93, Issue:1

    Topics: Aflatoxin B1; Animals; Blotting, Western; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Pyrazoles; Steroid Hydroxylases

1994
Differential xenobiotic induction of CYP2A5 in mouse liver, kidney, lung, and olfactory mucosa.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:8

    Topics: Amitrole; Animals; Aryl Hydrocarbon Hydroxylases; Cobalt; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; DNA Probes; Enzyme Induction; Griseofulvin; Immunoblotting; Isoenzymes; Kidney; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Olfactory Mucosa; Pyrazoles; RNA, Messenger; Substrate Specificity; Thioacetamide; Tin Compounds; Xenobiotics

1998
CYP2A5-mediated activation and early ultrastructural changes in the olfactory mucosa: studies on 2,6-dichlorophenyl methylsulfone.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzene Derivatives; Chlorzoxazone; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Injections, Intraperitoneal; Liver; Metyrapone; Mice; Microscopy, Electron, Transmission; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Olfactory Mucosa; Pyrazoles; Sulfhydryl Compounds; Sulfones

2006
Synthesis and molecular docking study of novel coumarin derivatives containing 4,5-dihydropyrazole moiety as potential antitumor agents.
    Bioorganic & medicinal chemistry letters, 2010, Oct-01, Volume: 20, Issue:19

    Topics: Antineoplastic Agents; Binding Sites; Catalytic Domain; Cell Line, Tumor; Computer Simulation; Coumarins; Humans; Protein Structure, Tertiary; Pyrazoles; Stomach Neoplasms; Telomerase

2010
Synthesis of new substituted chromen[4,3-c]pyrazol-4-ones and their antioxidant activities.
    Molecules (Basel, Switzerland), 2011, Dec-12, Volume: 16, Issue:12

    Topics: Antioxidants; Benzopyrans; Coumarins; Pyrazoles; Stereoisomerism

2011
Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase (CpIMPDH) inhibitors.
    Journal of medicinal chemistry, 2014, Dec-26, Volume: 57, Issue:24

    Topics: Acetanilides; Coumarins; Cryptosporidium parvum; Crystallography, X-Ray; Enzyme Inhibitors; IMP Dehydrogenase; In Vitro Techniques; Models, Molecular; Molecular Structure; Pyrazoles; Structure-Activity Relationship

2014
A novel pyrazole biscoumarin based chemosensors for the selective detection of Cu(2+) and Zn(2+) ions.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Sep-05, Volume: 148

    Topics: Cations; Copper; Coumarins; Fluorescent Dyes; Pyrazoles; Spectrometry, Fluorescence; Zinc

2015
Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes.
    Bioorganic & medicinal chemistry letters, 2015, Dec-15, Volume: 25, Issue:24

    Topics: Aldehydes; Anti-Bacterial Agents; Antineoplastic Agents; Binding Sites; Cell Line; Coumarins; Cytochrome P-450 CYP2A6; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Microsomes; Molecular Docking Simulation; Protein Structure, Tertiary; Pyrazoles

2015
Ethylene glycol promoted catalyst-free pseudo three-component green synthesis of bis(coumarin)s and bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s.
    Molecular diversity, 2016, Volume: 20, Issue:3

    Topics: Catalysis; Coumarins; Ethylene Glycol; Green Chemistry Technology; Molecular Structure; Pyrazoles; Stereoisomerism

2016
Design, synthesis and biological evaluation of novel 1,2,3-triazole linked coumarinopyrazole conjugates as potent anticholinesterase, anti-5-lipoxygenase, anti-tyrosinase and anti-cancer agents.
    Bioorganic chemistry, 2018, Volume: 80

    Topics: Alkynes; Antineoplastic Agents; Azides; Catalysis; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Copper; Coumarins; Cycloaddition Reaction; Drug Design; Humans; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Monophenol Monooxygenase; Pyrazoles; Structure-Activity Relationship; Triazoles

2018
Novel coumarin-pyrazole carboxamide derivatives as potential topoisomerase II inhibitors: Design, synthesis and antibacterial activity.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Anti-Bacterial Agents; Coumarins; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Design; Escherichia coli; Humans; Listeria monocytogenes; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Salmonella; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors

2018
Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids.
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Coumarins; Epithelial-Mesenchymal Transition; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Oximes; Pyrazoles; Structure-Activity Relationship; Transforming Growth Factor beta1

2019
Chlorosulfonic Acid Supported Piperidine-4-carboxylic Acid (PPCA) Functionalized Fe3O4 Nanoparticles (Fe3O4-PPCA): The Efficient, Green and Reusable Nanocatalyst for the Synthesis of Pyrazolyl Coumarin Derivatives under Solvent-Free Conditions.
    Combinatorial chemistry & high throughput screening, 2019, Volume: 22, Issue:2

    Topics: Catalysis; Coumarins; Green Chemistry Technology; Magnetite Nanoparticles; Pipecolic Acids; Pyrazoles; Solvents; Sulfonic Acids

2019
Pyrazole-coumarin and pyrazole-quinoline chalcones as potential antitubercular agents.
    Archiv der Pharmazie, 2020, Volume: 353, Issue:8

    Topics: Antitubercular Agents; Chalcones; Coumarins; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles; Quinolines; Software

2020
Synthesis and Antimicrobial Studies of Coumarin-Substituted Pyrazole Derivatives as Potent Anti-
    Molecules (Basel, Switzerland), 2020, Jun-15, Volume: 25, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Coumarins; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrazoles; Staphylococcal Infections; Staphylococcus aureus

2020
Designing Specific HSP70 Substrate Binding Domain Inhibitor for Perturbing Protein Folding Pathways to Inhibit Cancer Mechanism.
    Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:11

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Coumarins; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HSP70 Heat-Shock Proteins; Humans; MCF-7 Cells; Molecular Structure; Protein Folding; Pyrazoles; Structure-Activity Relationship

2021