pyrazole and transforming growth factor beta

pyrazole has been researched along with transforming growth factor beta in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Beight, D; Brooks, HB; Herron, DK; Jones, ML; Lampe, JW; McMillen, WT; Mort, N; Peng, SB; Sawyer, JS; Watkins, SA; Xia, X; Yan, L; Yingling, JM1
Choi, MK; Han, JM; Kim, HG; Lee, JS; Park, HJ; Son, CG; Son, SW; Wang, JH1
Chen, M; Hong, W; Paterson, IC; Sang, X; Wang, H; Wang, Y; Yang, X; You, X1
Guo, FY; Jiang, YJ; Jin, CH; Lan, XQ; Lian, LH; Lin, YC; Liu, J; Nan, JX; Ren, J; Wu, YL; Zhang, ZH; Zheng, GH1

Reviews

1 review(s) available for pyrazole and transforming growth factor beta

ArticleYear
Development of small molecule inhibitors targeting TGF-β ligand and receptor: Structures, mechanism, preclinical studies and clinical usage.
    European journal of medicinal chemistry, 2020, Apr-01, Volume: 191

    Topics: Animals; Drug Development; Humans; Ligands; Molecular Structure; Pyrazoles; Receptors, Transforming Growth Factor beta; Small Molecule Libraries; Transforming Growth Factor beta

2020

Other Studies

3 other study(ies) available for pyrazole and transforming growth factor beta

ArticleYear
Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
    Biochemistry, 2005, Feb-22, Volume: 44, Issue:7

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Chromatography, High Pressure Liquid; DNA-Binding Proteins; Epithelial Cells; Growth Inhibitors; HeLa Cells; Humans; Kinetics; MAP Kinase Kinase Kinases; Mass Spectrometry; Mesoderm; Mice; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Serine; Smad2 Protein; Smad3 Protein; Substrate Specificity; Trans-Activators; Transforming Growth Factor beta

2005
Aqueous extract of Artemisia capillaris exerts hepatoprotective action in alcohol-pyrazole-fed rat model.
    Journal of ethnopharmacology, 2013, Jun-03, Volume: 147, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Artemisia; Aspartate Aminotransferases; Blood Glucose; Catalase; Chemical and Drug Induced Liver Injury; Ethanol; Glutathione; Glutathione Peroxidase; Glutathione Reductase; L-Lactate Dehydrogenase; Male; Phytotherapy; Plant Extracts; Protective Agents; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin; Superoxide Dismutase; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha

2013
The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis.
    Bioorganic chemistry, 2022, Volume: 122

    Topics: Animals; Fibrosis; Liver Cirrhosis; Mice; Pyrazoles; Smad Proteins; Transforming Growth Factor beta

2022