Compounds > pyrazole

pyrazole and s-adenosylmethionine

pyrazole has been researched along with s-adenosylmethionine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cederbaum, AI; Wu, D1
Cederbaum, AI; Wang, X1
Caro, AA; Cederbaum, AI; Dey, A1
Cederbaum, AI; Zhuge, J1
Zhuge, J1

Other Studies

5 other study(ies) available for pyrazole and s-adenosylmethionine

ArticleYear
Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:4

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Hepatocytes; Male; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine

2006
S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Apoptosis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Enzyme Induction; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Protective Agents; Pyrazoles; S-Adenosylmethionine; Transaminases; Tumor Necrosis Factor-alpha

2006
S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Fragmentation; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria, Liver; Nitric Oxide Synthase Type II; Oxidative Stress; Pyrazoles; S-Adenosylmethionine

2007
Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes.
    Archives of biochemistry and biophysics, 2007, Oct-15, Volume: 466, Issue:2

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Chlormethiazole; Cycloleucine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Glutathione; Hepatocytes; Methionine Adenosyltransferase; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Adenosylmethionine

2007
A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.
    Molecular and cellular biochemistry, 2008, Volume: 314, Issue:1-2

    Topics: Animals; Apoptosis; Arachidonic Acid; Cell Survival; Cycloleucine; Cytochrome P-450 CYP2E1; Cytotoxins; Drug Synergism; Hepatocytes; Lipid Peroxidation; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Adenosylmethionine

2008