pyrazole and pyridine

pyrazole has been researched along with pyridine in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.70)	18.7374
1990's	1 (3.70)	18.2507
2000's	6 (22.22)	29.6817
2010's	12 (44.44)	24.3611
2020's	7 (25.93)	2.80

Authors

Authors	Studies
Hayashi, M; Iguchi, Y; Iizuka, K; Kajiwara, I; Kawamura, M; Miyamoto, T; Nakazawa, M; Ohyama, I; Okada, T; Taniguchi, K; Tanouchi, T	1
Fotsch, C; St Jean, DJ	1
Amet, Y; Berthou, F; Goasduff, T; Le Breton, L; Menez, JF; Salaun, JP	1
Abdel-Gawad, SM; El-Gaby, MS; Ghorab, MM	1
Kulys, J; Tetianec, L; Ziemys, A	1
Bouska, J; Bui, MH; Chen, Z; Claiborne, A; Kovar, P; Li, G; Lin, NH; Merta, PJ; Olson, A; Osterling, D; Park, C; Przytulinska, M; Rosenberg, SH; Sham, HL; Sowin, TJ; Stewart, KD; Tao, ZF; Tong, Y; Zhang, H	1
Chen, W; Zhou, Y	1
Ballav, N; Buck, M; Grohmann, A; Haryono, M; Shen, C; Weidner, T; Zharnikov, M	1
El-Sayed Ali, T	1
Doytchinova, I; Geronikaki, A; Kapadia, K; Soković, M; Solankee, A	1
Li, Z; Shan, H; Wan, L; Xing, N; Xing, Y; Zhang, C	1
Starck, M; Ziessel, R	1
deSchoolmeester, J; Gerhardt, S; Hargreaves, D; Kilgour, E; Mayers, RM; Ogg, DJ; Packer, MJ; Rees, A; Scott, JS; Selmi, N; Stocker, A; Swales, JG; Whittamore, PR	1
Li, Y; Li, Z; Liu, Q; Mao, M; Xiong, L; Zhang, X; Zhou, Y	1
Huang, S; Lei, F; Nie, Y; Shen, L	1
Chae, CH; Cho, SY; Ha, JD; Jung, H; Kim, HR; Lee, BH; Lee, JH; Oh, KS; Seo, HW; Yun, CS	1
Duan, GY; Ge, YQ; Jia, J; Sun, HW; Wang, JW; Wang, T	1
Barker, JJ; Bromidge, SM; Brookfield, FA; Burch, JD; Chen, Y; Eigenbrot, C; Heifetz, A; Ismaili, MHA; Johnson, A; Krülle, TM; MacKinnon, CH; Maghames, R; McEwan, PA; Montalbetti, CAGN; Ortwine, DF; Pei, Z; Pérez-Fuertes, Y; Trani, G; Vaidya, DG; Wang, X; Zarrin, AA	1
Benabbes, R; Bouakka, M; Feron, O; Mabkhot, YN; Radi, S; Riant, O; Tighadouini, S	1
Boerth, JA; Ellman, JA; Hummel, JR	1
Dennis Bilavendran, J; Manikandan, A; Sivakumar, K; Thangarasu, P	1
Chung, CY; Lin, CY; Takayama, H; Tsai, SE; Tseng, CC; Uramaru, N; Wong, FF	1
Cherukupalli, S; Du, X; Jia, H; Liu, X; Yu, J; Zhan, P	1
El-Ansary, RA; Milad, YR; Mohareb, RM	1
Elmetwally, AM; Mohamed, AA; Mohareb, RM	1
Adhikary, A; Akhtar, S; Bala, S; Chowdhuri, SP; Das, BB; Das, KS; De, A; Ghosh, A; Huang, GZ; Mondal, R; Saha, S; Tong, ML	1
Cespedes, O; Galadzhun, I; Halcrow, MA; Howard, MJ; Kulmaczewski, R; Shahid, N	1

Reviews

1 review(s) available for pyrazole and pyridine

Article	Year
Mitigating heterocycle metabolism in drug discovery. Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13 Topics: Animals; Biotransformation; Databases, Factual; Drug Discovery; Drug Interactions; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Pharmaceutical Preparations; Rats	2012

Other Studies

26 other study(ies) available for pyrazole and pyridine

Article	Year
Highly selective inhibitors of thromboxane synthetase. 2. Pyridine derivatives. Journal of medicinal chemistry, 1981, Volume: 24, Issue:10 Topics: Animals; Oxidoreductases; Pyridines; Sheep; Structure-Activity Relationship; Thromboxane-A Synthase	1981
Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. Biochemical and biophysical research communications, 1994, Sep-15, Volume: 203, Issue:2 Topics: Acetone; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Hydroxylation; Isoenzymes; Lauric Acids; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley	1994
Synthesis and antifungal activity of novel pyrano[2',3':4,5]thiazolo[2,3-b]quinazolines, pyrido[2',3':4,5]thiazolo[2,3-b]quinazolines and pyrazolo[2',3':4,5]thiazolo[2,3-b]quinazolines. Farmaco (Societa chimica italiana : 1989), 2000, Volume: 55, Issue:4 Topics: Antifungal Agents; Aspergillus flavus; Aspergillus ochraceus; Candida albicans; Microbial Sensitivity Tests; Molecular Structure; Penicillium chrysogenum; Pyrans; Pyrazoles; Pyridines; Quinazolines; Thiazoles	2000
Probing Aspergillus niger glucose oxidase with pentacyanoferrate(III) aza- and thia-complexes. Journal of inorganic biochemistry, 2006, Volume: 100, Issue:10 Topics: Aspergillus niger; Benzimidazoles; Ferric Compounds; Glucose Oxidase; Histidine; Imidazoles; Models, Chemical; Models, Molecular; Oxidation-Reduction; Pyrazoles; Pyridines; Structure-Activity Relationship; Thiadiazoles; Triazoles	2006
Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability. Bioorganic & medicinal chemistry letters, 2007, Oct-15, Volume: 17, Issue:20 Topics: Administration, Oral; Animals; Checkpoint Kinase 1; Cyanides; Hydrogen; Indenes; Inhibitory Concentration 50; Mice; Molecular Structure; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Pyridines; Rats; Structure-Activity Relationship	2007
Novel neutral octanuclear copper(I) complexes stabilized by pyridine linked bis(pyrazolate) ligands. Dalton transactions (Cambridge, England : 2003), 2007, Nov-28, Issue:44 Topics: Copper; Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Pyrazoles; Pyridines	2007
Self-assembled monolayers of a bis(pyrazol-1-yl)pyridine-substituted thiol on Au(111). Langmuir : the ACS journal of surfaces and colloids, 2008, Nov-18, Volume: 24, Issue:22 Topics: Carbon; Carboxylic Acids; Gold Radioisotopes; Imines; Microscopy, Scanning Tunneling; Molecular Conformation; Nitrogen; Perylene; Photons; Pyrazoles; Pyridines; Sulfhydryl Compounds; Surface Properties; Temperature	2008
Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Animals; Anti-Infective Agents; Artemia; Biological Assay; Escherichia coli; Fungi; Microbial Sensitivity Tests; Molecular Structure; Pyrazoles; Pyridines; Pyrimidines; Staphylococcus aureus; Staphylococcus epidermidis; Triazines	2009
Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:2 Topics: Anti-Infective Agents; Bacteria; Chalcone; Microbial Sensitivity Tests; Pyrazoles; Pyridines; Pyrimidines; Quantitative Structure-Activity Relationship; Thermodynamics; Triazines	2010
Neutral mononuclear, dinuclear, tetranuclear d7/d10 metal complexes containing bis-pyrazole/pyridine ligands supported by 2,6-bis(3-pyrazolyl)pyridine: synthesis, structure, spectra, and catalytic activity. Inorganic chemistry, 2012, Jun-18, Volume: 51, Issue:12 Topics: Catalysis; Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Pyrazoles; Pyridines; Quantum Theory; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Transition Elements	2012
Multifunctionalized luminescent lanthanide complexes from nonadentate phosphonylated bis-pyrazolyl-pyridine ligands. Dalton transactions (Cambridge, England : 2003), 2012, Nov-21, Volume: 41, Issue:43 Topics: Coordination Complexes; Europium; Lanthanoid Series Elements; Ligands; Organophosphonates; Pyrazoles; Pyridines; Spectrophotometry, Ultraviolet; Terbium	2012
Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). Journal of medicinal chemistry, 2012, Nov-26, Volume: 55, Issue:22 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adipose Tissue; Animals; Benzoates; Dogs; Enzyme Inhibitors; Glucuronides; Guinea Pigs; Humans; Liver; Macaca fascicularis; Mice; Models, Molecular; Molecular Structure; Protein Conformation; Pyrazoles; Pyridines; Rats; Rats, Wistar; Structure-Activity Relationship; Substrate Specificity	2012
Synthesis and insecticidal evaluation of novel N-pyridylpyrazolecarboxamides containing cyano substituent in the ortho-position. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Amides; Animals; Calcium; Insecticides; Larva; Moths; Pyrazoles; Pyridines; Ryanodine Receptor Calcium Release Channel	2013
An efficient microwave-assisted Suzuki reaction using a new pyridine-pyrazole/Pd(II) species as catalyst in aqueous media. Molecules (Basel, Switzerland), 2013, Jan-25, Volume: 18, Issue:2 Topics: Boronic Acids; Catalysis; Chemistry, Organic; Crystallography, X-Ray; Ligands; Microwaves; Molecular Conformation; Palladium; Pyrazoles; Pyridines; Recycling; Solvents; Spectrophotometry, Ultraviolet; Water	2013
Design and synthesis of novel 3-(benzo[d]oxazol-2-yl)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine derivatives as selective G-protein-coupled receptor kinase-2 and -5 inhibitors. Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24 Topics: Amines; Benzoxazoles; Binding Sites; Catalytic Domain; Drug Design; Enzyme Activation; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 5; Molecular Docking Simulation; Protein Binding; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Structure-Activity Relationship	2013
The synthesis, characterization and optical properties of novel 5-(3-aryl-1H-pyrazol-5-yl)-2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-1,3,4-oxadiazole. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Apr-05, Volume: 123 Topics: Crystallography, X-Ray; Halogenation; Magnetic Resonance Spectroscopy; Models, Molecular; Oxadiazoles; Pyrazoles; Pyridines; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet	2014
Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK). Bioorganic & medicinal chemistry letters, 2014, Dec-15, Volume: 24, Issue:24 Topics: Binding Sites; Crystallography, X-Ray; Drug Design; Kinetics; Molecular Dynamics Simulation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Structure-Activity Relationship; Sulfones	2014
Synthesis of Novel β-Keto-Enol Derivatives Tethered Pyrazole, Pyridine and Furan as New Potential Antifungal and Anti-Breast Cancer Agents. Molecules (Basel, Switzerland), 2015, Nov-10, Volume: 20, Issue:11 Topics: Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Female; Fungi; Furans; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrazoles; Pyridines	2015
Highly Stereoselective Cobalt(III)-Catalyzed Three-Component C-H Bond Addition Cascade. Angewandte Chemie (International ed. in English), 2016, 10-04, Volume: 55, Issue:41 Topics: Aldehydes; Amines; Catalysis; Cobalt; Imines; Molecular Structure; Pyrazoles; Pyridines; Stereoisomerism	2016
Synthesis and discovery of pyrazolo-pyridine analogs as inflammation medications through pro- and anti-inflammatory cytokine and COX-2 inhibition assessments. Bioorganic chemistry, 2020, Volume: 94 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Dose-Response Relationship, Drug; Drug Discovery; Humans; Lipopolysaccharides; Macrophages; Mice; Molecular Docking Simulation; Molecular Structure; Pyrazoles; Pyridines; Structure-Activity Relationship	2020
Selective Synthesis and Photoluminescence Study of Pyrazolopyridopyridazine Diones and Molecules (Basel, Switzerland), 2020, May-21, Volume: 25, Issue:10 Topics: Fluorescence; Hydrazines; Luminol; Pyrazoles; Pyridines; Pyridones	2020
Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. European journal of medicinal chemistry, 2020, Sep-15, Volume: 202 Topics: Antiviral Agents; Capsid Proteins; Dose-Response Relationship, Drug; Drug Design; Hepatitis B e Antigens; Hepatitis B virus; Microbial Sensitivity Tests; Molecular Structure; Pyrazines; Pyrazoles; Pyridines; Pyrimidines; Structure-Activity Relationship; Thiazoles; Virus Replication	2020
New Approaches for the Synthesis of Fused Thiophene, Pyrazole, Pyran and Pyridine Derivatives with Anti-Proliferative Together with c-Met Kinase and Prostate Cancer Cell Inhibitions. Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:13 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrans; Pyrazoles; Pyridines; Structure-Activity Relationship; Thiophenes	2021
Multi-Component Reactions of Cyclohexan-1,3-dione: Synthesis of Fused Pyran, Pyridine, Thiophene and Pyrazole Derivatives with c-Met, Anti-Proliferative Activities. Anti-cancer agents in medicinal chemistry, 2021, Volume: 21, Issue:17 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclohexanones; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Protein Kinase Inhibitors; Pyrans; Pyrazoles; Pyridines; Receptor Protein-Tyrosine Kinases; Structure-Activity Relationship; Thiophenes	2021
Lanthanide clusters of phenanthroline containing a pyridine-pyrazole based ligand: magnetism and cell imaging. Dalton transactions (Cambridge, England : 2003), 2021, Mar-16, Volume: 50, Issue:10 Topics: Coordination Complexes; Humans; Lanthanoid Series Elements; Ligands; Magnetic Phenomena; MCF-7 Cells; Molecular Structure; Optical Imaging; Phenanthrolines; Pyrazoles; Pyridines	2021
The flexibility of long chain substituents influences spin-crossover in isomorphous lipid bilayer crystals. Chemical communications (Cambridge, England), 2021, Apr-22, Volume: 57, Issue:33 Topics: Alkanes; Coordination Complexes; Crystallography, X-Ray; Ferrous Compounds; Ligands; Lipid Bilayers; Models, Molecular; Phase Transition; Pyrazoles; Pyridines; Structure-Activity Relationship; Transition Temperature	2021