pyrazole has been researched along with piperidines in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Krishnamurthy, M; Li, W; Moore, BM | 1 |
| Min, J; Plemper, RK; Prussia, A; Snyder, JP; Sun, A; Yang, Y; Yin, Y; Yoon, JJ | 1 |
| Kruse, CG; Lange, JH | 1 |
| Chang, CP; Chao, YS; Chiu, HH; Chu, CM; Chung, WL; Hsieh, WP; Hung, MS; Kuo, CW; Lin, Y; Shia, KS; Song, JS; Tai, CL; Tseng, SL; Tung, YS; Wu, CH | 1 |
| Chao, YS; Chiu, HH; Chu, CM; Hsieh, MT; Hung, MS; Kuo, CW; Shia, KS; Song, JS; Suja, TD | 1 |
| Fong, O; Fong, TM; Muise, ES; Qian, S; Thompson, JR; Weingarth, D; Zhao, W | 1 |
| Bader, SJ; Bagley, SW; Bernhardson, DJ; Cabral, S; Edmonds, DJ; Griffith, DA; Kung, DW; Polivkova, J; Rose, CR; Southers, JA; Yang, X | 1 |
| Bonin, PD; Cai, C; Chen, Y; Cornelius, P; DeNinno, MP; Futatsugi, K; Gao, H; Guimarães, CR; Hamilton, MD; Hank, R; Harris, AR; Kalgutkar, AS; Kung, DW; Lavergne, SY; Lefker, BA; Lopaze, MG; Mascitti, V; McClure, KF; Morishita, N; Munchhof, MJ; Preville, C; Robinson, RP; Wright, SW | 1 |
| Andrés, M; Buil, MA; Calbet, M; Casado, O; Castro, J; Eastwood, PR; Eichhorn, P; Ferrer, M; Forns, P; Moreno, I; Petit, S; Roberts, RS | 1 |
| Baset, MA; El-Eraky, WI; Fahmy, HH; Khalifa, NM; Nossier, ES | 1 |
| Alexander, R; Espiritu, C; Flores, OA; Hartman, GD; Klumpp, K; Kuduk, SD; Lam, AM; Lau, V; Stoops, B; Vogel, R | 1 |
11 other study(ies) available for pyrazole and piperidines
| Article | Year |
|---|---|
Synthesis, biological evaluation, and structural studies on N1 and C5 substituted cycloalkyl analogues of the pyrazole class of CB1 and CB2 ligands.
Topics: Animals; Biochemistry; CHO Cells; Cricetinae; Drug Evaluation, Preclinical; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship | 2004 |
Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex.
Topics: Drug Evaluation, Preclinical; Enzyme Inhibitors; Imidazoles; Ligands; Measles virus; Models, Molecular; Molecular Structure; Nucleosides; Piperidines; Protein Binding; Pyrazoles; Quantitative Structure-Activity Relationship; RNA-Dependent RNA Polymerase; Virus Internalization | 2008 |
Cannabinoid CB1 receptor antagonists in therapeutic and structural perspectives.
Topics: Animals; Anti-Obesity Agents; CHO Cells; Cricetinae; Cricetulus; Humans; Imidazoles; Isomerism; Models, Chemical; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Solubility; Structure-Activity Relationship; Thiazoles; Triazoles; Water | 2008 |
Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antag
Topics: Animals; Binding Sites; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Obese; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Structure-Activity Relationship; Thiophenes; Weight Loss | 2008 |
Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists.
Topics: Amides; Cell Line; Humans; Isomerism; Molecular Structure; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Structure-Activity Relationship | 2008 |
Genome-wide expression profiling revealed peripheral effects of cannabinoid receptor 1 inverse agonists in improving insulin sensitivity and metabolic parameters.
Topics: Adipose Tissue; Animals; Cannabinoid Receptor Agonists; Down-Regulation; Homozygote; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Knockout; Mice, Obese; Piperidines; PPAR alpha; PPAR gamma; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Transcriptional Activation | 2010 |
Synthesis of 7-oxo-dihydrospiro[indazole-5,4'-piperidine] acetyl-CoA carboxylase inhibitors.
Topics: Acetyl-CoA Carboxylase; Alkenes; Alkylation; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Indazoles; Ketones; Piperidines; Pyrazoles; Stereoisomerism; Substrate Specificity | 2012 |
From partial to full agonism: identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor.
Topics: Carbamates; Humans; Piperidines; Protein Binding; Pyrazoles; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2013 |
Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of pyrrolopiperidinone acetic acids as CRTh2 antagonists.
Topics: Acetates; Administration, Oral; Animals; Caco-2 Cells; Cell Membrane Permeability; Half-Life; Humans; Piperidines; Pyrazoles; Rats; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship | 2014 |
Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Celecoxib; Cyclooxygenase Inhibitors; Drug Design; Edema; Heterocyclic Compounds; Injections; Male; Molecular Docking Simulation; Piperidines; Pyrazoles; Rats; Rimonabant | 2017 |
Identification of a new class of HBV capsid assembly modulator.
Topics: Antiviral Agents; Capsid Proteins; Dose-Response Relationship, Drug; Hepatitis B virus; Microbial Sensitivity Tests; Molecular Structure; Piperidines; Pyrazoles; Structure-Activity Relationship | 2021 |